bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0146_orf1
Length=151
Score E
Sequences producing significant alignments: (Bits) Value
dre:570956 sgk2a, fm82b06, sgk2, wu:fm82b06, zgc:172111, zgc:1... 79.3 4e-15
dre:559050 sgk2b, MGC154065, zgc:154065; serum/glucocorticoid ... 78.6 7e-15
dre:324140 sgk1, cb1083, sgk, wu:fc20a09; serum/glucocorticoid... 77.0 2e-14
ath:AT5G62310 IRE; IRE (INCOMPLETE ROOT HAIR ELONGATION); kina... 76.3 4e-14
ath:AT3G17850 protein kinase, putative 75.5 6e-14
sce:YCR091W KIN82, FPK2; Kin82p (EC:2.7.11.1); K08286 protein-... 75.1 7e-14
ath:AT2G25090 CIPK16; CIPK16 (CBL-INTERACTING PROTEIN KINASE 1... 75.1 8e-14
sce:YNR047W FPK1; Fpk1p (EC:2.7.11.1); K08286 protein-serine/t... 75.1 8e-14
bbo:BBOV_III005470 17.m07489; protein kinase domain containing... 75.1 8e-14
cel:W10G6.2 sgk-1; Serum- and Glucocorticoid- inducible kinase... 73.2 3e-13
mmu:27219 Sgk2, AI098171, AW146006, Sgkl; serum/glucocorticoid... 73.2 3e-13
hsa:10110 SGK2, H-SGK2, dJ138B7.2; serum/glucocorticoid regula... 73.2 3e-13
sce:YOL100W PKH2; Pkh2p (EC:2.7.11.1); K08286 protein-serine/t... 72.8 4e-13
hsa:100533105 C8orf44-SGK3, DKFZp779G0825; C8orf44-SGK3 readth... 72.4 5e-13
hsa:23678 SGK3, CISK, DKFZp781N0293, SGK2, SGKL; serum/glucoco... 72.4 5e-13
mmu:170755 Sgk3, 2510015P22Rik, A330005P07Rik, Cisk, fy, fz; s... 72.4 5e-13
dre:403000 pdpk1b, MGC77318, zgc:77318; 3-phosphoinositide dep... 72.0 6e-13
ath:AT1G48490 kinase 71.6 8e-13
hsa:100509979 putative 3-phosphoinositide-dependent protein ki... 71.2 1e-12
xla:399130 sgk1-a, Sgk, sgk-A, sgk1; serum/glucocorticoid regu... 71.2 1e-12
mmu:20393 Sgk1, Sgk; serum/glucocorticoid regulated kinase 1 (... 71.2 1e-12
hsa:6446 SGK1, SGK; serum/glucocorticoid regulated kinase 1 (E... 71.2 1e-12
mmu:18607 Pdpk1, Pdk1; 3-phosphoinositide dependent protein ki... 71.2 1e-12
hsa:5170 PDPK1, MGC20087, MGC35290, PDK1, PRO0461; 3-phosphoin... 71.2 1e-12
dre:768202 pdpk1a, zgc:153787; 3-phosphoinositide dependent pr... 70.9 1e-12
ath:AT1G45160 kinase 70.9 2e-12
cel:W04B5.5 hypothetical protein 70.1 2e-12
xla:444529 pdpk1, MGC82080; 3-phosphoinositide dependent prote... 70.1 3e-12
tgo:TGME49_118770 protein kinase, putative (EC:2.7.11.17) 69.7 3e-12
dre:768159 wu:fk56c04, zgc:154030; si:ch211-195b13.1 69.7 4e-12
xla:444618 sgk1-b, MGC84110, Sgk, sgk-B, sgk2; serum/glucocort... 69.3 4e-12
dre:338219 rps6ka3a, id:ibd1103, rps6ka3, si:ch211-114c12.12, ... 69.3 4e-12
sce:YDR490C PKH1; Pkh1p (EC:2.7.11.1) 69.3 5e-12
tpv:TP02_0399 calcium-dependent protein kinase; K13412 calcium... 69.3 5e-12
ath:AT2G45490 AtAUR3; AtAUR3 (ATAURORA3); ATP binding / histon... 68.9 6e-12
ath:AT1G29230 CIPK18; CIPK18 (CBL-INTERACTING PROTEIN KINASE 1... 68.9 6e-12
dre:100009657 rps6ka3b, zgc:158386; ribosomal protein S6 kinas... 68.6 7e-12
mmu:22241 Ulk1, AU041434, Unc51.1, mKIAA0722; Unc-51 like kina... 68.6 8e-12
mmu:20112 Rps6ka2, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk... 68.6 8e-12
hsa:27330 RPS6KA6, PP90RSK4, RSK4; ribosomal protein S6 kinase... 68.2 9e-12
ath:AT2G30360 SIP4; SIP4 (SOS3-INTERACTING PROTEIN 4); kinase/... 67.8 1e-11
mmu:110651 Rps6ka3, MPK-9, Rsk2, S6K-alpha3, pp90RSK2; ribosom... 67.8 1e-11
hsa:6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RS... 67.8 1e-11
ath:AT4G32830 AtAUR1; AtAUR1 (ATAURORA1); histone kinase(H3-S1... 67.4 2e-11
hsa:8408 ULK1, ATG1, ATG1A, FLJ38455, FLJ46475, UNC51, Unc51.1... 67.4 2e-11
mmu:67071 Rps6ka6, 2610524K04Rik, RSK4; ribosomal protein S6 k... 67.0 2e-11
dre:564523 sgk3, zgc:162253; serum/glucocorticoid regulated ki... 67.0 2e-11
dre:337670 rps6kal, fj94b02, rps6ka6, wu:fj94b02, zgc:66139; r... 67.0 2e-11
cel:Y50D7A.3 hypothetical protein 67.0 2e-11
mmu:20111 Rps6ka1, Rsk1, p90rsk, rsk; ribosomal protein S6 kin... 66.6 3e-11
> dre:570956 sgk2a, fm82b06, sgk2, wu:fm82b06, zgc:172111, zgc:198213;
serum/glucocorticoid regulated kinase 2a (EC:2.7.11.1);
K13303 serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
Length=361
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 82/150 (54%), Gaps = 18/150 (12%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD +A++G+G G+V ++ G AVKV+ K+ + + ++ ++ E+
Sbjct 29 DFDF------LAVIGKGTFGKVLLAKLKADGKFYAVKVLQKKVILKKKE-QKNIMAERNV 81
Query 63 LVALSAGGRSV-HPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAA 121
L+ +S+ HP +V L ++QT+E LYFVL Y L L+R C S A
Sbjct 82 LL------KSLKHPFLVGLHYSFQTSEKLYFVLDYVNGGELFYHLQRERC----FSEPRA 131
Query 122 RLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
R + AE+A+A+ + +++RD++PENI+
Sbjct 132 RFYTAEVASAIGYLHSLNIVYRDLKPENIL 161
> dre:559050 sgk2b, MGC154065, zgc:154065; serum/glucocorticoid
regulated kinase 2b; K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=404
Score = 78.6 bits (192), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 52/149 (34%), Positives = 77/149 (51%), Gaps = 16/149 (10%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD + ++G G+ G+VF T R +G AVKV+ K + +R R V+ E
Sbjct 76 DFDY------LKVIGTGSFGKVFLATHRENGKYYAVKVLQKHIILTRKE-ERNVMCEHRV 128
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L+ HP +V L ++QT E LY VL YA L L+R G + AR
Sbjct 129 LLKTLN-----HPFLVKLHFSFQTKERLYLVLDYACGGELFYHLQREGVFGEA----RAR 179
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+AAE+A AL + +++RD++PENI+
Sbjct 180 FYAAEMACALGYLHSLKIVYRDLKPENIL 208
> dre:324140 sgk1, cb1083, sgk, wu:fc20a09; serum/glucocorticoid
regulated kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=433
Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/149 (31%), Positives = 76/149 (51%), Gaps = 16/149 (10%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD + ++G+G+ G+V RS AVKV+ K+ + + + ++ E+
Sbjct 99 DFDF------LKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKE-EKHIMSERNV 151
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L+ HP +V L ++QT + LYFVL Y L L+R C AR
Sbjct 152 LLK-----NVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERC----FLEPRAR 202
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+AAEIA+AL + +++RD++PENI+
Sbjct 203 FYAAEIASALGYLHSLNIVYRDLKPENIL 231
> ath:AT5G62310 IRE; IRE (INCOMPLETE ROOT HAIR ELONGATION); kinase/
protein serine/threonine kinase
Length=1168
Score = 76.3 bits (186), Expect = 4e-14, Method: Composition-based stats.
Identities = 46/149 (30%), Positives = 76/149 (51%), Gaps = 17/149 (11%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DF+ P + RGA GRVF +R++GD A+KV+ K + R +L E+
Sbjct 753 DFEIIKP------ISRGAFGRVFLAKKRATGDLFAIKVLKKADM-IRKNAVESILAERNI 805
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L+++ +P VV ++ E+LY V+ Y L +LR L C L AR
Sbjct 806 LISVR------NPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGC----LDEDMAR 855
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
++ AE+ AL + ++HRD++P+N++
Sbjct 856 IYIAEVVLALEYLHSVNIIHRDLKPDNLL 884
> ath:AT3G17850 protein kinase, putative
Length=1296
Score = 75.5 bits (184), Expect = 6e-14, Method: Composition-based stats.
Identities = 45/150 (30%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query 2 RDFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKE 61
RD + + + + RGA GRVF +R++GD A+KV+ K + R +L E++
Sbjct 874 RDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADM-IRKNAVESILAERD 932
Query 62 ALVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAA 121
L+ + +P VV ++ ++LY V+ Y L +LR L C L
Sbjct 933 ILINVR------NPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGC----LEEDIV 982
Query 122 RLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
R++ AE+ AL + GV+HRD++P+N++
Sbjct 983 RVYIAEVVLALEYLHSEGVVHRDLKPDNLL 1012
> sce:YCR091W KIN82, FPK2; Kin82p (EC:2.7.11.1); K08286 protein-serine/threonine
kinase [EC:2.7.11.-]
Length=720
Score = 75.1 bits (183), Expect = 7e-14, Method: Composition-based stats.
Identities = 46/141 (32%), Positives = 76/141 (53%), Gaps = 13/141 (9%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ LLG+G VG+V+ ER + A+KV+ K + R +++R VL E+E L S
Sbjct 327 IRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKR-VLTEQEILAT------S 379
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVL--RRLSCAGLSLSVGAARLWAAEIAA 130
HP +V L ++QT + LY + Y L R+ C ++ A+ +A+E+ A
Sbjct 380 DHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKC----IAEEDAKFYASEVVA 435
Query 131 ALAAMRGRGVLHRDIRPENIV 151
AL + G ++RD++PENI+
Sbjct 436 ALEYLHLLGFIYRDLKPENIL 456
> ath:AT2G25090 CIPK16; CIPK16 (CBL-INTERACTING PROTEIN KINASE
16); ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=469
Score = 75.1 bits (183), Expect = 8e-14, Method: Composition-based stats.
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 10/137 (7%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
LLG G +V+ TE S+GD VA+KV+ K + R + Q+ E + L H
Sbjct 20 LLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLR------H 73
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P+VV LR T + ++FV+ Y L +++ R L AR + ++ +A+
Sbjct 74 PNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDG----KLPEDLARKYFQQLISAVDF 129
Query 135 MRGRGVLHRDIRPENIV 151
RGV HRDI+PEN++
Sbjct 130 CHSRGVFHRDIKPENLL 146
> sce:YNR047W FPK1; Fpk1p (EC:2.7.11.1); K08286 protein-serine/threonine
kinase [EC:2.7.11.-]
Length=893
Score = 75.1 bits (183), Expect = 8e-14, Method: Composition-based stats.
Identities = 46/141 (32%), Positives = 76/141 (53%), Gaps = 13/141 (9%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ LLG+G VG+VF E+ + A+KV+ K + R++++R VL E+E L S
Sbjct 499 IRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKR-VLTEQEILAT------S 551
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVL--RRLSCAGLSLSVGAARLWAAEIAA 130
HP +V L ++Q+ + LY + Y L R+ C + AR +A+E+ A
Sbjct 552 NHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKC----ICEDDARFYASEVTA 607
Query 131 ALAAMRGRGVLHRDIRPENIV 151
AL + G ++RD++PENI+
Sbjct 608 ALEYLHLLGFIYRDLKPENIL 628
> bbo:BBOV_III005470 17.m07489; protein kinase domain containing
protein; K13412 calcium-dependent protein kinase [EC:2.7.11.1]
Length=755
Score = 75.1 bits (183), Expect = 8e-14, Method: Composition-based stats.
Identities = 40/136 (29%), Positives = 70/136 (51%), Gaps = 14/136 (10%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
LG+G+ G+V + + +G+ AVKV+ K + + R++R++ I K HP
Sbjct 306 LGKGSYGQVLKACHKETGEVKAVKVIRKAAIENAMRMKREITIMKNL----------DHP 355
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
++V L Y+ E LY V+ L + + R C + R ++ +A+A
Sbjct 356 NIVKLLEIYEDEECLYLVMEMCSGGELFEEIVRRGCFSEQYAATMMR----QLFSAIAYC 411
Query 136 RGRGVLHRDIRPENIV 151
G+G+LHRD++PENI+
Sbjct 412 HGKGILHRDLKPENIL 427
> cel:W10G6.2 sgk-1; Serum- and Glucocorticoid- inducible kinase
homolog family member (sgk-1); K08792 serum/glucocorticoid-regulated
kinase, invertebrate [EC:2.7.11.1]
Length=463
Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats.
Identities = 40/136 (29%), Positives = 74/136 (54%), Gaps = 10/136 (7%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G+G+ GRV++ + + A+K++ K +R ++ ++ V+ E+ L+ HP
Sbjct 141 IGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVK-HVMAERNVLI-----NNFKHP 194
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+V L ++Q E LYFVL + L L+R S +R +AAEIA AL +
Sbjct 195 FLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREK----HFSESRSRFYAAEIACALGYL 250
Query 136 RGRGVLHRDIRPENIV 151
+ +++RD++PEN++
Sbjct 251 HEKNIIYRDLKPENLL 266
> mmu:27219 Sgk2, AI098171, AW146006, Sgkl; serum/glucocorticoid
regulated kinase 2 (EC:2.7.11.1); K13303 serum/glucocorticoid-regulated
kinase 2 [EC:2.7.11.1]
Length=367
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 46/150 (30%), Positives = 80/150 (53%), Gaps = 18/150 (12%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD + ++G+G G+V +S G AVKV+ K+ + +++ + ++ E+
Sbjct 34 DFDF------LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSIL-KNKEQNHIMAERNV 86
Query 63 LVALSAGGRSV-HPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAA 121
L+ ++V HP +V LR ++QT E LYFVL Y L L+R A
Sbjct 87 LL------KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRER----RFLEPRA 136
Query 122 RLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
R + AE+A+A+ + +++RD++PENI+
Sbjct 137 RFYTAEVASAIGYLHSLNIIYRDLKPENIL 166
> hsa:10110 SGK2, H-SGK2, dJ138B7.2; serum/glucocorticoid regulated
kinase 2 (EC:2.7.11.1); K13303 serum/glucocorticoid-regulated
kinase 2 [EC:2.7.11.1]
Length=367
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 47/150 (31%), Positives = 79/150 (52%), Gaps = 18/150 (12%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD + ++G+G G+V +S G AVKV+ K+ + + + ++ E+
Sbjct 34 DFDF------LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKE-QSHIMAERSV 86
Query 63 LVALSAGGRSV-HPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAA 121
L+ ++V HP +V LR ++QT E LYFVL Y L L+R A
Sbjct 87 LL------KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRER----RFLEPRA 136
Query 122 RLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
R +AAE+A+A+ + +++RD++PENI+
Sbjct 137 RFYAAEVASAIGYLHSLNIIYRDLKPENIL 166
> sce:YOL100W PKH2; Pkh2p (EC:2.7.11.1); K08286 protein-serine/threonine
kinase [EC:2.7.11.-]
Length=1081
Score = 72.8 bits (177), Expect = 4e-13, Method: Composition-based stats.
Identities = 49/138 (35%), Positives = 71/138 (51%), Gaps = 10/138 (7%)
Query 14 ALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSV 73
+++G GA V T + A KV+ K L R + + V IEK AL L+
Sbjct 183 SVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYL-IRQKKVKYVSIEKTALQKLNNS---- 237
Query 74 HPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALA 133
PSVV L T+Q SLYF+L YA ++++ SL AR +AA+I A+
Sbjct 238 -PSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYG----SLDETCARYYAAQIIDAID 292
Query 134 AMRGRGVLHRDIRPENIV 151
+ G++HRDI+PENI+
Sbjct 293 YLHSNGIIHRDIKPENIL 310
> hsa:100533105 C8orf44-SGK3, DKFZp779G0825; C8orf44-SGK3 readthrough
(EC:2.7.11.1)
Length=496
Score = 72.4 bits (176), Expect = 5e-13, Method: Composition-based stats.
Identities = 44/139 (31%), Positives = 75/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V + G AVKV+ K+ + +R ++ ++ E+ L+
Sbjct 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKE-QKHIMAERNVLLK-----NV 218
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QT E LYFVL + L L+R S AR +AAEIA+AL
Sbjct 219 KHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRER----SFPEHRARFYAAEIASAL 274
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 275 GYLHSIKIVYRDLKPENIL 293
> hsa:23678 SGK3, CISK, DKFZp781N0293, SGK2, SGKL; serum/glucocorticoid
regulated kinase family, member 3 (EC:2.7.11.1); K13304
serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
Length=496
Score = 72.4 bits (176), Expect = 5e-13, Method: Composition-based stats.
Identities = 44/139 (31%), Positives = 75/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V + G AVKV+ K+ + +R ++ ++ E+ L+
Sbjct 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKE-QKHIMAERNVLLK-----NV 218
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QT E LYFVL + L L+R S AR +AAEIA+AL
Sbjct 219 KHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRER----SFPEHRARFYAAEIASAL 274
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 275 GYLHSIKIVYRDLKPENIL 293
> mmu:170755 Sgk3, 2510015P22Rik, A330005P07Rik, Cisk, fy, fz;
serum/glucocorticoid regulated kinase 3 (EC:2.7.11.1); K13304
serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
Length=496
Score = 72.4 bits (176), Expect = 5e-13, Method: Composition-based stats.
Identities = 44/139 (31%), Positives = 75/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V + G AVKV+ K+ + +R ++ ++ E+ L+
Sbjct 165 LKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKE-QKHIMAERNVLLK-----NV 218
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QT E LYFVL + L L+R S AR +AAEIA+AL
Sbjct 219 KHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRER----SFPEPRARFYAAEIASAL 274
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 275 GYLHSIKIVYRDLKPENIL 293
> dre:403000 pdpk1b, MGC77318, zgc:77318; 3-phosphoinositide dependent
protein kinase-1b (EC:2.7.11.1); K06276 3-phosphoinositide
dependent protein kinase-1 [EC:2.7.11.1]
Length=537
Score = 72.0 bits (175), Expect = 6e-13, Method: Composition-based stats.
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++G A+K++ KR + ++ + V E++ + L H
Sbjct 65 ILGEGSFSTVVLAKEHTTGKEYAIKILEKRHIMKENK-AQYVKRERDIMSHLD------H 117
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P V L T+Q E LYF L YA L +R++ S R ++AEI AL
Sbjct 118 PFFVKLYFTFQDEEKLYFGLSYAKNGELLKYIRKIG----SFDETCTRFYSAEIVCALEY 173
Query 135 MRGRGVLHRDIRPENIV 151
+ +G++HRD++PENI+
Sbjct 174 LHQKGIIHRDLKPENIL 190
> ath:AT1G48490 kinase
Length=1235
Score = 71.6 bits (174), Expect = 8e-13, Method: Composition-based stats.
Identities = 40/136 (29%), Positives = 71/136 (52%), Gaps = 11/136 (8%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+ RGA G V + ++GD A+KV+ K + R +L E++ L+ + +P
Sbjct 834 ISRGAFGHVILARKNTTGDLFAIKVLRKADM-IRKNAVESILAERDILI------NARNP 886
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
VV ++ +E+LY V+ Y +LR++ C L AR++ AE+ AL +
Sbjct 887 FVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGC----LDEANARVYIAEVVLALEYL 942
Query 136 RGRGVLHRDIRPENIV 151
GV+HRD++P+N++
Sbjct 943 HSEGVVHRDLKPDNLL 958
> hsa:100509979 putative 3-phosphoinositide-dependent protein
kinase 2-like
Length=442
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++ A+K++ KR + +++ V E++ + L H
Sbjct 106 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVP-YVTRERDVMSRLD------H 158
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P V L T+QT LYF L YA L +R++ S R + AEI +AL
Sbjct 159 PFFVKLYFTFQTTRRLYFGLSYAKNGELLKYIRKIG----SFDETCTRFYTAEIVSALEY 214
Query 135 MRGRGVLHRDIRPENIV 151
+ G+G++HRD++PENI+
Sbjct 215 LHGKGIIHRDLKPENIL 231
> xla:399130 sgk1-a, Sgk, sgk-A, sgk1; serum/glucocorticoid regulated
kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=434
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 72/139 (51%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V ++ AVKV+ K+ + + + ++ E+ L+
Sbjct 104 LKIIGKGSFGKVLLARHQADEKFYAVKVLQKKAILKKKE-EKHIMSERNVLLK-----NV 157
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QT LYF+L Y L L+R C AR +AAEIA+AL
Sbjct 158 KHPFLVGLHFSFQTTSRLYFILDYINGGELFYHLQRERC----FLEPRARFYAAEIASAL 213
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 214 GYLHSLNIVYRDLKPENIL 232
> mmu:20393 Sgk1, Sgk; serum/glucocorticoid regulated kinase 1
(EC:2.7.11.1); K13302 serum/glucocorticoid-regulated kinase
1 [EC:2.7.11.1]
Length=524
Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats.
Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V ++ AVKV+ K+ + + + ++ E+ L+
Sbjct 194 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKE-EKHIMSERNVLLK-----NV 247
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QTA+ LYFVL Y L L+R C AR +AAEIA+AL
Sbjct 248 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC----FLEPRARFYAAEIASAL 303
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 304 GYLHSLNIVYRDLKPENIL 322
> hsa:6446 SGK1, SGK; serum/glucocorticoid regulated kinase 1
(EC:2.7.11.1); K13302 serum/glucocorticoid-regulated kinase
1 [EC:2.7.11.1]
Length=526
Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats.
Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V ++ AVKV+ K+ + + + ++ E+ L+
Sbjct 196 LKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKE-EKHIMSERNVLLK-----NV 249
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QTA+ LYFVL Y L L+R C AR +AAEIA+AL
Sbjct 250 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC----FLEPRARFYAAEIASAL 305
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 306 GYLHSLNIVYRDLKPENIL 324
> mmu:18607 Pdpk1, Pdk1; 3-phosphoinositide dependent protein
kinase 1 (EC:2.7.11.1); K06276 3-phosphoinositide dependent
protein kinase-1 [EC:2.7.11.1]
Length=522
Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats.
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++ A+K++ KR + +++ V E++ + L H
Sbjct 90 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVP-YVTRERDVMSRLD------H 142
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P V L T+Q E LYF L YA L +R++ S R + AEI +AL
Sbjct 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIG----SFDETCTRFYTAEIVSALEY 198
Query 135 MRGRGVLHRDIRPENIV 151
+ G+G++HRD++PENI+
Sbjct 199 LHGKGIIHRDLKPENIL 215
> hsa:5170 PDPK1, MGC20087, MGC35290, PDK1, PRO0461; 3-phosphoinositide
dependent protein kinase-1 (EC:2.7.11.1); K06276 3-phosphoinositide
dependent protein kinase-1 [EC:2.7.11.1]
Length=556
Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats.
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++ A+K++ KR + +++ V E++ + L H
Sbjct 87 ILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVP-YVTRERDVMSRLD------H 139
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P V L T+Q E LYF L YA L +R++ S R + AEI +AL
Sbjct 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIG----SFDETCTRFYTAEIVSALEY 195
Query 135 MRGRGVLHRDIRPENIV 151
+ G+G++HRD++PENI+
Sbjct 196 LHGKGIIHRDLKPENIL 212
> dre:768202 pdpk1a, zgc:153787; 3-phosphoinositide dependent
protein kinase-1a (EC:2.7.11.1)
Length=536
Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats.
Identities = 43/137 (31%), Positives = 69/137 (50%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++G A+K++ K +R ++ V+ EK+ L + H
Sbjct 82 ILGEGSFSTVVLAKELATGKEYAMKILEKNHIRKENK-AHYVIREKDILSCID------H 134
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P V L T+Q ++ LYF L YA L +R++ S R + AEI AL
Sbjct 135 PFFVKLFFTFQDSQKLYFALSYAKNGELLRYIRKIG----SFDETCTRFYTAEIVCALEY 190
Query 135 MRGRGVLHRDIRPENIV 151
+ G++HRD++PENI+
Sbjct 191 LHTVGIIHRDLKPENIL 207
> ath:AT1G45160 kinase
Length=1067
Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats.
Identities = 41/149 (27%), Positives = 79/149 (53%), Gaps = 17/149 (11%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DF+ P + RGA G+VF +R++GD A+KV+ K + ++ + R +L E+
Sbjct 669 DFEIIKP------ISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIER-ILQERNI 721
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L+ + +P +V ++ ++LY V+ Y L +L+++ C L AR
Sbjct 722 LITVR------YPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGC----LDEEIAR 771
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
++ AE+ AL + ++HRD++P+N++
Sbjct 772 IYIAELVLALEYLHSLKIVHRDLKPDNLL 800
> cel:W04B5.5 hypothetical protein
Length=320
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 43/140 (30%), Positives = 78/140 (55%), Gaps = 8/140 (5%)
Query 16 LGRGAVGRVF----RCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGR 71
+G G+ V+ + + VA+K+ KR L ++++ + EKEAL AL +
Sbjct 32 VGEGSFSTVYLARRKEPKNDENPEVALKICLKR-LILKNKMVPYIHREKEAL-ALISREE 89
Query 72 SVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAA 131
+ HP +V L T+Q +ESLYFVL YA L ++++ + +V +R +AA + +A
Sbjct 90 NAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDS--KFNVADSRYYAANLLSA 147
Query 132 LAAMRGRGVLHRDIRPENIV 151
L + G++HRD++ +N++
Sbjct 148 LEHIHKLGIIHRDVKADNLL 167
> xla:444529 pdpk1, MGC82080; 3-phosphoinositide dependent protein
kinase-1 (EC:2.7.11.1); K06276 3-phosphoinositide dependent
protein kinase-1 [EC:2.7.11.1]
Length=506
Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats.
Identities = 44/137 (32%), Positives = 68/137 (49%), Gaps = 11/137 (8%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
+LG G+ V E ++G A+K++ KR + +++ V EKE + L H
Sbjct 38 ILGEGSFSTVVLAKELTTGREFAIKILQKRHILKENKVL-YVTREKEVMSCLD------H 90
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
V L T+Q E LYF L YA L +R++ S R + AEI AL
Sbjct 91 SFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIG----SFDETCTRFYTAEIVCALEY 146
Query 135 MRGRGVLHRDIRPENIV 151
+ +G++HRD++PENI+
Sbjct 147 LHEKGIIHRDLKPENIL 163
> tgo:TGME49_118770 protein kinase, putative (EC:2.7.11.17)
Length=2326
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/122 (34%), Positives = 73/122 (59%), Gaps = 12/122 (9%)
Query 31 SSGDSVA-VKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHPSVVHLRRTYQTAES 89
S D+VA VKV+ K + ++ R+R QV E++ + L HP++V +++ +
Sbjct 2105 SENDTVAAVKVLSKANI-AQMRIREQVKKERDIHLGLE------HPNIVRFFSSFEDDQQ 2157
Query 90 LYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAMRGRGVLHRDIRPEN 149
LYFVL YA +LRD L+R C + + A ++ ++A AL + G+G++HRD++PEN
Sbjct 2158 LYFVLEYANGGTLRDRLKR--CHHIQETEAAHLIF--QLADALCYLHGKGIIHRDLKPEN 2213
Query 150 IV 151
++
Sbjct 2214 LL 2215
> dre:768159 wu:fk56c04, zgc:154030; si:ch211-195b13.1
Length=423
Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 16/149 (10%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DFD + ++G+G+ G+V + + AVKV+ K+ + + ++ ++ E+
Sbjct 90 DFDY------LKIIGKGSFGKVLLARHKENELYYAVKVLQKKIIMKKKE-QKHIMAERSV 142
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L+ HP +V L ++QT + LYFVL Y L L+R AR
Sbjct 143 LMK-----NIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERV----FLEPRAR 193
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+AAEIA+AL + +++RD++PENI+
Sbjct 194 FYAAEIASALGYLHSLHIVYRDLKPENIL 222
> xla:444618 sgk1-b, MGC84110, Sgk, sgk-B, sgk2; serum/glucocorticoid
regulated kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=434
Score = 69.3 bits (168), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 71/139 (51%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V ++ AVKV+ K+ + + + ++ E+ L+
Sbjct 104 LKIIGKGSFGKVLLARHKADEKFYAVKVLQKKAILKKKE-EKHIMSERNVLLK-----NV 157
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L + QT LYF+L Y L L+R C AR +AAEIA+AL
Sbjct 158 KHPFLVGLHFSIQTTSRLYFILDYINGGELFYHLQRERC----FLEPRARFYAAEIASAL 213
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 214 GYLHSLNIVYRDLKPENIL 232
> dre:338219 rps6ka3a, id:ibd1103, rps6ka3, si:ch211-114c12.12,
wu:fk86e02, zgc:56006; ribosomal protein S6 kinase, polypeptide
3a (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=732
Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats.
Identities = 45/140 (32%), Positives = 78/140 (55%), Gaps = 15/140 (10%)
Query 15 LLGRGAVGRVFRCTERSSGDS---VAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGR 71
+LG+G+ G+VF + S D+ A+KV+ K L+ R R+R + +E++ LV ++
Sbjct 64 VLGQGSFGKVFLVKKISGPDAGQLYAMKVLKKATLKVRDRVRTK--MERDILVEVN---- 117
Query 72 SVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAA 131
HP +V L +QT LY +L + D+ RLS + + + + AE+A A
Sbjct 118 --HPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTEEDVKFYLAELALA 171
Query 132 LAAMRGRGVLHRDIRPENIV 151
L + G G+++RD++PENI+
Sbjct 172 LDHLHGLGIIYRDLKPENIL 191
Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats.
Identities = 36/136 (26%), Positives = 60/136 (44%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC ++S+G AVK++ K RR E E L+ HP
Sbjct 420 IGVGSYSVCKRCVQKSTGMDYAVKIIKKE--------RRDPTEEVEILLRYGQ-----HP 466
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ + S+Y V L D + R S +A L+ I + +
Sbjct 467 NIITLKDVFDDGRSVYLVTELMKGGELLDKILRQKF--FSEREASAVLYT--ITKTVEYL 522
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 523 HAQGVVHRDLKPSNIL 538
> sce:YDR490C PKH1; Pkh1p (EC:2.7.11.1)
Length=766
Score = 69.3 bits (168), Expect = 5e-12, Method: Composition-based stats.
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 10/136 (7%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
LG G+ V T R SG AVKV+ K L R + + V +EK AL L+
Sbjct 131 LGDGSYSSVVLATARDSGKKYAVKVLSKEYL-IRQKKVKYVTVEKLALQKLNGT-----K 184
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+ L T+Q SLYF+L YA ++++ SL+ AR +A++I A+ ++
Sbjct 185 GIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYG----SLNETCARYYASQIIDAVDSL 240
Query 136 RGRGVLHRDIRPENIV 151
G++HRDI+PENI+
Sbjct 241 HNIGIIHRDIKPENIL 256
> tpv:TP02_0399 calcium-dependent protein kinase; K13412 calcium-dependent
protein kinase [EC:2.7.11.1]
Length=844
Score = 69.3 bits (168), Expect = 5e-12, Method: Composition-based stats.
Identities = 41/136 (30%), Positives = 70/136 (51%), Gaps = 14/136 (10%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
LG G+ G V + + SG A+K++ K + + R++R++ I K HP
Sbjct 406 LGNGSYGNVLKGVHKESGAVRAIKIILKSKIENAMRMKREIQIMKTL----------DHP 455
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L Y+ A+ LY V+ L D R +S G S + A+ + ++ +A+A
Sbjct 456 NIIKLFEVYEDADCLYLVMEMCVGGELFD--RIVSTNGFSEAYAASIM--RQVFSAIAYC 511
Query 136 RGRGVLHRDIRPENIV 151
R VLHRD++PENI+
Sbjct 512 HNRNVLHRDLKPENIL 527
> ath:AT2G45490 AtAUR3; AtAUR3 (ATAURORA3); ATP binding / histone
kinase(H3-S10 specific) / protein kinase; K08850 aurora
kinase, other [EC:2.7.11.1]
Length=288
Score = 68.9 bits (167), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 17/149 (11%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEA 62
DF+ P LG+G GRV+ E S VA+KV++K + + ++ Q+ E E
Sbjct 21 DFEIGRP------LGKGKFGRVYLAREAKSKYIVALKVIFKEQIE-KYKIHHQLRREMEI 73
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
+L HP+++ L + E ++ +L YA L VL++ L+ A
Sbjct 74 QTSLR------HPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNG----HLTEQQAA 123
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+ A ++ ALA G+ V+HRDI+PEN++
Sbjct 124 TYIASLSQALAYCHGKCVIHRDIKPENLL 152
> ath:AT1G29230 CIPK18; CIPK18 (CBL-INTERACTING PROTEIN KINASE
18); ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=520
Score = 68.9 bits (167), Expect = 6e-12, Method: Composition-based stats.
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 18/140 (12%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSR---SRLRRQVLIEKEALVALSAGGR 71
LLG G +V+ SGD VA+KV+ K + + ++R++ I + R
Sbjct 79 LLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILR----------R 128
Query 72 SVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAA 131
HP +VHL T +YFV+ Y G L + + A L AR + ++ ++
Sbjct 129 VRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTV-----AKGRLPEETARRYFQQLISS 183
Query 132 LAAMRGRGVLHRDIRPENIV 151
++ GRGV HRD++PEN++
Sbjct 184 VSFCHGRGVYHRDLKPENLL 203
> dre:100009657 rps6ka3b, zgc:158386; ribosomal protein S6 kinase,
polypeptide 3b (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase
[EC:2.7.11.1]
Length=720
Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats.
Identities = 44/140 (31%), Positives = 78/140 (55%), Gaps = 15/140 (10%)
Query 15 LLGRGAVGRVF---RCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGR 71
+LG+G+ G+VF + T +G A+KV+ K L+ R ++R + +E++ LV ++
Sbjct 72 VLGQGSFGKVFLVKKTTGPDAGQLYAMKVLKKATLKVRDQVRTK--MERDILVEVN---- 125
Query 72 SVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAA 131
HP +V L +QT LY +L + D+ RLS + + + + AE+A A
Sbjct 126 --HPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTEEDVKFYLAELALA 179
Query 132 LAAMRGRGVLHRDIRPENIV 151
L + G G+++RD++PENI+
Sbjct 180 LDHLHGLGIIYRDLKPENIL 199
> mmu:22241 Ulk1, AU041434, Unc51.1, mKIAA0722; Unc-51 like kinase
1 (C. elegans) (EC:2.7.11.1); K08269 unc51-like kinase
[EC:2.7.11.1]
Length=1051
Score = 68.6 bits (166), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 16/139 (11%)
Query 15 LLGRGAVGRVFRCTERSSGD-SVAVKVVYKRPL-RSRSRLRRQVLIEKEALVALSAGGRS 72
L+G GA VF+ R D VAVK + K+ L +S++ L +++ I KE
Sbjct 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL---------- 70
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
H ++V L + A S+Y V+ Y L D L + +LS RL+ +IA A+
Sbjct 71 KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMR----TLSEDTVRLFLQQIAGAM 126
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +G++HRD++P+NI+
Sbjct 127 RLLHSKGIIHRDLKPQNIL 145
> mmu:20112 Rps6ka2, 90kDa, D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk,
pp90rsk; ribosomal protein S6 kinase, polypeptide 2 (EC:2.7.11.1);
K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=733
Score = 68.6 bits (166), Expect = 8e-12, Method: Composition-based stats.
Identities = 46/153 (30%), Positives = 83/153 (54%), Gaps = 17/153 (11%)
Query 4 FDASSP--YVPVALLGRGAVGRVF---RCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLI 58
F+ + P + + +LG+G+ G+VF + T +G A+KV+ K L+ R R+R + +
Sbjct 51 FEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSK--M 108
Query 59 EKEALVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSV 118
E++ L ++ HP +V L +QT LY +L + D+ RLS + +
Sbjct 109 ERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTE 158
Query 119 GAARLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+ + AE+A AL + G G+++RD++PENI+
Sbjct 159 EDVKFYLAELALALDHLHGLGIIYRDLKPENIL 191
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC +++ AVK++ K +R E E L+ HP
Sbjct 421 IGVGSYSVCKRCVHKATDAEYAVKIIDKS--------KRDPSEEIEILLRYGQ-----HP 467
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ Y + +Y V+ L D + R C S A IA + +
Sbjct 468 NIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRC----FSEREASDVLYTIARTMDYL 523
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 524 HSQGVVHRDLKPSNIL 539
> hsa:27330 RPS6KA6, PP90RSK4, RSK4; ribosomal protein S6 kinase,
90kDa, polypeptide 6 (EC:2.7.11.1); K04373 p90 ribosomal
S6 kinase [EC:2.7.11.1]
Length=745
Score = 68.2 bits (165), Expect = 9e-12, Method: Composition-based stats.
Identities = 45/142 (31%), Positives = 79/142 (55%), Gaps = 15/142 (10%)
Query 13 VALLGRGAVGRVFRCTERSSGDS---VAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAG 69
+ +LG+G+ G+VF +++ D+ A+KV+ K L+ R R+R + +E++ LV ++
Sbjct 76 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTK--MERDILVEVN-- 131
Query 70 GRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIA 129
HP +V L +QT LY +L + DV RLS L + + + AE+A
Sbjct 132 ----HPFIVKLHYAFQTEGKLYLILDFLRGG---DVFTRLSKEVL-FTEEDVKFYLAELA 183
Query 130 AALAAMRGRGVLHRDIRPENIV 151
AL + G+++RD++PENI+
Sbjct 184 LALDHLHQLGIVYRDLKPENIL 205
Score = 36.6 bits (83), Expect = 0.032, Method: Composition-based stats.
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC ++ AVK++ K +R E E L+ HP
Sbjct 432 IGVGSYSVCKRCIHATTNMEFAVKIIDKS--------KRDPSEEIEILMRYGQ-----HP 478
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ + +Y V L D + + C S + L+ I+ + +
Sbjct 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKC--FSEREASDILYV--ISKTVDYL 534
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 535 HCQGVVHRDLKPSNIL 550
> ath:AT2G30360 SIP4; SIP4 (SOS3-INTERACTING PROTEIN 4); kinase/
protein kinase
Length=435
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 10/137 (7%)
Query 15 LLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVH 74
LLG GA +VF +R +G SVAVK++ K+ L + L + E + LS H
Sbjct 26 LLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLS------H 79
Query 75 PSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAA 134
P++V L T ++F + + L ++S G LS +R + ++ +A+
Sbjct 80 PNIVKLHEVMATKSKIFFAMEFVKGGEL---FNKISKHG-RLSEDLSRRYFQQLISAVGY 135
Query 135 MRGRGVLHRDIRPENIV 151
RGV HRD++PEN++
Sbjct 136 CHARGVYHRDLKPENLL 152
> mmu:110651 Rps6ka3, MPK-9, Rsk2, S6K-alpha3, pp90RSK2; ribosomal
protein S6 kinase polypeptide 3 (EC:2.7.11.1); K04373 p90
ribosomal S6 kinase [EC:2.7.11.1]
Length=740
Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats.
Identities = 45/147 (30%), Positives = 80/147 (54%), Gaps = 15/147 (10%)
Query 8 SPYVPVALLGRGAVGRVFRCTERSSGDS---VAVKVVYKRPLRSRSRLRRQVLIEKEALV 64
S + + +LG+G+ G+VF + S D+ A+KV+ K L+ R R+R + +E++ LV
Sbjct 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTK--MERDILV 123
Query 65 ALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLW 124
++ HP +V L +QT LY +L + D+ RLS + + + +
Sbjct 124 EVN------HPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTEEDVKFY 173
Query 125 AAEIAAALAAMRGRGVLHRDIRPENIV 151
AE+A AL + G+++RD++PENI+
Sbjct 174 LAELALALDHLHSLGIIYRDLKPENIL 200
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC +++ AVK++ K +R E E L+ HP
Sbjct 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKS--------KRDPTEEIEILLRYGQ-----HP 474
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ Y + +Y V L D + R S +A L+ I + +
Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF--FSEREASAVLFT--ITKTVEYL 530
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 531 HAQGVVHRDLKPSNIL 546
> hsa:6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK,
RSK2, S6K-alpha3, p90-RSK2, pp90RSK2; ribosomal protein S6 kinase,
90kDa, polypeptide 3 (EC:2.7.11.1); K04373 p90 ribosomal
S6 kinase [EC:2.7.11.1]
Length=740
Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats.
Identities = 45/147 (30%), Positives = 80/147 (54%), Gaps = 15/147 (10%)
Query 8 SPYVPVALLGRGAVGRVFRCTERSSGDS---VAVKVVYKRPLRSRSRLRRQVLIEKEALV 64
S + + +LG+G+ G+VF + S D+ A+KV+ K L+ R R+R + +E++ LV
Sbjct 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTK--MERDILV 123
Query 65 ALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLW 124
++ HP +V L +QT LY +L + D+ RLS + + + +
Sbjct 124 EVN------HPFIVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTEEDVKFY 173
Query 125 AAEIAAALAAMRGRGVLHRDIRPENIV 151
AE+A AL + G+++RD++PENI+
Sbjct 174 LAELALALDHLHSLGIIYRDLKPENIL 200
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC +++ AVK++ K +R E E L+ HP
Sbjct 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKS--------KRDPTEEIEILLRYGQ-----HP 474
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ Y + +Y V L D + R S +A L+ I + +
Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF--FSEREASAVLFT--ITKTVEYL 530
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 531 HAQGVVHRDLKPSNIL 546
> ath:AT4G32830 AtAUR1; AtAUR1 (ATAURORA1); histone kinase(H3-S10
specific) / kinase/ protein serine/threonine kinase; K08850
aurora kinase, other [EC:2.7.11.1]
Length=294
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 48/152 (31%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query 3 DFDASSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRS---RSRLRRQVLIE 59
DFD P LGRG G V+ E+ S VA+KV++K L+ +LRR+V I+
Sbjct 30 DFDIGKP------LGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQ 83
Query 60 KEALVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVG 119
HP+++ L + + +Y +L YA L L++ C S
Sbjct 84 SHLR----------HPNILRLYGYFYDQKRVYLILEYAARGELYKDLQK--CKYFSERRA 131
Query 120 AARLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
A + A +A AL G+ V+HRDI+PEN++
Sbjct 132 AT--YVASLARALIYCHGKHVIHRDIKPENLL 161
> hsa:8408 ULK1, ATG1, ATG1A, FLJ38455, FLJ46475, UNC51, Unc51.1;
unc-51-like kinase 1 (C. elegans) (EC:2.7.11.1); K08269
unc51-like kinase [EC:2.7.11.1]
Length=1050
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 16/139 (11%)
Query 15 LLGRGAVGRVFRCTERSSGD-SVAVKVVYKRPL-RSRSRLRRQVLIEKEALVALSAGGRS 72
L+G GA VF+ R D VAVK + K+ L +S++ L +++ I KE
Sbjct 21 LIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKEL---------- 70
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
H ++V L + A S+Y V+ Y L D L + +LS RL+ +IA A+
Sbjct 71 KHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMR----TLSEDTIRLFLQQIAGAM 126
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +G++HRD++P+NI+
Sbjct 127 RLLHSKGIIHRDLKPQNIL 145
> mmu:67071 Rps6ka6, 2610524K04Rik, RSK4; ribosomal protein S6
kinase polypeptide 6 (EC:2.7.11.1); K04373 p90 ribosomal S6
kinase [EC:2.7.11.1]
Length=860
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 45/142 (31%), Positives = 79/142 (55%), Gaps = 15/142 (10%)
Query 13 VALLGRGAVGRVFRCTERSSGDS---VAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAG 69
+ +LG+G+ G+VF +++ D+ A+KV+ K L+ R R+R + +E++ LV ++
Sbjct 192 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTK--MERDILVEVN-- 247
Query 70 GRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIA 129
HP +V L +QT LY +L + DV RLS L + + + AE+A
Sbjct 248 ----HPFIVKLHYAFQTEGKLYLILDFLRGG---DVFTRLSKEVL-FTEEDVKFYLAELA 299
Query 130 AALAAMRGRGVLHRDIRPENIV 151
AL + G+++RD++PENI+
Sbjct 300 LALDHLHRLGIVYRDLKPENIL 321
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC +S AVK++ K +R E E L+ HP
Sbjct 548 IGIGSYSVCKRCIHSASNVEFAVKIIDKN--------KRDPSEEIEILMRYGQ-----HP 594
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ + + +Y V L D + + C S + L+ I + +
Sbjct 595 NIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKC--FSEQEASNVLYV--ITKTVECL 650
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 651 HSQGVVHRDLKPSNIL 666
> dre:564523 sgk3, zgc:162253; serum/glucocorticoid regulated
kinase family, member 3 (EC:2.7.11.1); K13304 serum/glucocorticoid-regulated
kinase 3 [EC:2.7.11.1]
Length=486
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 10/139 (7%)
Query 13 VALLGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRS 72
+ ++G+G+ G+V + G A+KV+ K+ + +R R ++ ++ E+ L+
Sbjct 155 LKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKKVILNR-REQKHIMAERNVLLK-----NV 208
Query 73 VHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAAL 132
HP +V L ++QT + LYFVL + L L++ + A+ + AE+A+AL
Sbjct 209 KHPFLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKER----TFPEPRAKFYIAEMASAL 264
Query 133 AAMRGRGVLHRDIRPENIV 151
+ +++RD++PENI+
Sbjct 265 GYLHSLNIVYRDLKPENIL 283
> dre:337670 rps6kal, fj94b02, rps6ka6, wu:fj94b02, zgc:66139;
ribosomal protein S6 kinase, like (EC:2.7.11.1); K04373 p90
ribosomal S6 kinase [EC:2.7.11.1]
Length=740
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 47/154 (30%), Positives = 81/154 (52%), Gaps = 16/154 (10%)
Query 1 CRDFDASSPYVPVALLGRGAVGRVF---RCTERSSGDSVAVKVVYKRPLRSRSRLRRQVL 57
C D S + + +LG+G+ G+VF + +G A+KV+ K L+ R R+R +
Sbjct 59 CEKADPSQ-FELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKASLKVRDRVRTK-- 115
Query 58 IEKEALVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLS 117
+E++ LV ++ HP +V L +QT LY +L + DV RLS + +
Sbjct 116 MERDILVEVN------HPFIVKLHYAFQTEGKLYLILDFLRGG---DVFTRLS-KEVMFT 165
Query 118 VGAARLWAAEIAAALAAMRGRGVLHRDIRPENIV 151
+ + AE+A AL + G+++RD++PENI+
Sbjct 166 EEDVKFYLAELALALDHLHNLGIVYRDLKPENIL 199
Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats.
Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 17/136 (12%)
Query 16 LGRGAVGRVFRCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALVALSAGGRSVHP 75
+G G+ RC R + AVK++ K +R E E L+ HP
Sbjct 426 IGVGSYSICKRCIHRVTAMEFAVKIIDKS--------KRDPSEEIEILMRYGQ-----HP 472
Query 76 SVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLWAAEIAAALAAM 135
+++ L+ Y +Y V L D + R S +A L+ I + +
Sbjct 473 NIITLKDVYDEGRFVYLVTELMKGGELLDKILRQKF--FSEREASAVLYT--ITKTVDYL 528
Query 136 RGRGVLHRDIRPENIV 151
+GV+HRD++P NI+
Sbjct 529 HCQGVVHRDLKPSNIL 544
> cel:Y50D7A.3 hypothetical protein
Length=485
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 47/149 (31%), Positives = 71/149 (47%), Gaps = 13/149 (8%)
Query 7 SSPYVPVALLGRGAVGRVFRCTERSSGDSVAVKVV----YKRPLRSRSRLRRQVLIEKEA 62
++ Y +LGRG V RC E+ SG AVK+V K+ RL + + E E
Sbjct 28 NAAYESKEVLGRGLASTVRRCIEKGSGQHFAVKIVDISTEKQSENEAKRLLEETISEVEI 87
Query 63 LVALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAAR 122
L LS HPS++ + YQT L+ V A L DVL + +++S AR
Sbjct 88 LRQLSG-----HPSIIKIHDFYQTPSFLFAVFEMAPRGELFDVLN----STVTVSEKRAR 138
Query 123 LWAAEIAAALAAMRGRGVLHRDIRPENIV 151
++ + M R ++HRD++ ENI+
Sbjct 139 RLMKQLFDGVEYMHARDIVHRDLKLENIL 167
> mmu:20111 Rps6ka1, Rsk1, p90rsk, rsk; ribosomal protein S6 kinase
polypeptide 1 (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase
[EC:2.7.11.1]
Length=735
Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 45/147 (30%), Positives = 78/147 (53%), Gaps = 15/147 (10%)
Query 8 SPYVPVALLGRGAVGRVF---RCTERSSGDSVAVKVVYKRPLRSRSRLRRQVLIEKEALV 64
S + + +LG+G+ G+VF + T SG A+KV+ K L+ R R+R + +E++ L
Sbjct 60 SQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTK--MERDILA 117
Query 65 ALSAGGRSVHPSVVHLRRTYQTAESLYFVLHYAGAASLRDVLRRLSCAGLSLSVGAARLW 124
++ HP VV L +QT LY +L + D+ RLS + + + +
Sbjct 118 DVN------HPFVVKLHYAFQTEGKLYLILDFLRGG---DLFTRLS-KEVMFTEEDVKFY 167
Query 125 AAEIAAALAAMRGRGVLHRDIRPENIV 151
AE+A L + G+++RD++PENI+
Sbjct 168 LAELALGLDHLHSLGIIYRDLKPENIL 194
Lambda K H
0.325 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 3199347004
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40