bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0188_orf1
Length=169
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subu... 271 8e-73
hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1); K... 188 8e-48
mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.... 186 4e-47
tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subu... 181 1e-45
dre:561941 protein kinase, X-linked-like; K04345 protein kinas... 174 1e-43
mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP d... 170 2e-42
hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase, c... 169 3e-42
xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba; ... 169 3e-42
cel:ZK909.2 kin-1; protein KINase family member (kin-1); K0434... 169 4e-42
cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain ... 167 2e-41
dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,... 166 3e-41
dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;... 166 4e-41
xla:100101276 prkaca; protein kinase, cAMP-dependent, catalyti... 165 8e-41
xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent, ... 165 8e-41
hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; prot... 164 1e-40
dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent... 164 1e-40
mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catal... 163 3e-40
dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinas... 160 1e-39
hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent, ... 155 7e-38
bbo:BBOV_III005740 17.m07511; protein kinase domain containing... 154 1e-37
tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subu... 153 2e-37
cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:... 151 1e-36
pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase... 146 4e-35
dre:566430 cGMP dependent protein kinase I 138 1e-32
mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b; p... 137 2e-32
cel:Y47D3A.16 rsks-1; RSK-pSeventy (RSK-p70 kinase) homolog fa... 137 2e-32
sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 pro... 137 2e-32
hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK, P... 137 2e-32
dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,... 135 5e-32
tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein ki... 135 6e-32
dre:100125912 prkg2; protein kinase, cGMP-dependent, type II (... 135 8e-32
dre:571965 protein kinase N2-like; K06071 protein kinase N [EC... 133 3e-31
sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K043... 133 3e-31
hsa:5586 PKN2, MGC150606, MGC71074, PAK2, PRK2, PRKCL2, PRO204... 132 8e-31
sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase ... 131 8e-31
xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent, ty... 130 2e-30
mmu:109333 Pkn2, 6030436C20Rik, AI507382, PRK2, Prkcl2, Stk7; ... 129 4e-30
dre:100332055 prkce; protein kinase C, epsilon 129 5e-30
tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11... 128 7e-30
hsa:5581 PRKCE, MGC125656, MGC125657, PKCE, nPKC-epsilon; prot... 128 9e-30
mmu:18754 Prkce, 5830406C15Rik, PKC[e], PKCepsilon, Pkce, R751... 128 1e-29
dre:560549 akt3a, akt3, si:ch211-221n23.2; v-akt murine thymom... 128 1e-29
hsa:6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1; ribosomal protei... 127 2e-29
dre:556339 protein kinase, cGMP-dependent, type II-like; K0737... 126 3e-29
mmu:20111 Rps6ka1, Rsk1, p90rsk, rsk; ribosomal protein S6 kin... 126 4e-29
xla:399376 rps6ka3, MGC82193, S6KII, p90, rsk, rsk2; ribosomal... 126 4e-29
dre:571285 ribosomal protein S6 kinase, polypeptide 2-like; K0... 126 4e-29
cel:E01H11.1 pkc-2; Protein Kinase C family member (pkc-2); K0... 125 5e-29
dre:560840 hypothetical LOC560840; K06071 protein kinase N [EC... 125 5e-29
mmu:23797 Akt3, AI851531, D930002M15Rik, Nmf350; thymoma viral... 125 5e-29
> tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subunit
(EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=514
Score = 271 bits (693), Expect = 8e-73, Method: Compositional matrix adjust.
Identities = 125/157 (79%), Positives = 136/157 (86%), Gaps = 0/157 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RTWTLCGTHEYLAPESITRRGHGL VDWWALGILLFEMLAG PPFVD+ PLGIY+KIIAG
Sbjct 355 RTWTLCGTHEYLAPESITRRGHGLPVDWWALGILLFEMLAGHPPFVDENPLGIYRKIIAG 414
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
KIEFP FD +AKSL+KRLL H+P KRYGCLKDGAEDVKNHKFF+GIDW CY + IR P
Sbjct 415 KIEFPRSFDYAAKSLVKRLLTHDPLKRYGCLKDGAEDVKNHKFFKGIDWVKCYNKNIRAP 474
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPVIDSVTQQALF 169
Y PN +GP+DSSMFD YAESTESS+P I + QQA F
Sbjct 475 YLPNTRGPQDSSMFDKYAESTESSSPPIGAAEQQAFF 511
> hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=358
Score = 188 bits (477), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 88/151 (58%), Positives = 112/151 (74%), Gaps = 1/151 (0%)
Query 10 CVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKI 69
V RTWTLCGT EYLAPE I +GHG VDWWALGIL+FEML+G PPF DD P GIY+KI
Sbjct 197 LVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKI 256
Query 70 IAGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKI 129
+AGKI+FP D K LIK+LL+ + +R G +K+GA DVK+H++FR +DWE QRK+
Sbjct 257 LAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKL 316
Query 130 RPPYKPNIQGPRDSSMFDTYAEST-ESSAPV 159
+PP P I G D+S F+TY E+ +++APV
Sbjct 317 KPPIVPKIAGDGDTSNFETYPENDWDTAAPV 347
> mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=355
Score = 186 bits (472), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 85/150 (56%), Positives = 109/150 (72%), Gaps = 0/150 (0%)
Query 11 VGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKII 70
V RTWTLCGT EYLAPE I +GHG VDWWALGIL+FEML+G PPF DD P GIY+KI+
Sbjct 195 VDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKIL 254
Query 71 AGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIR 130
A KI+FP D ++K LIK+LL+ + +R G +K+GAED+K H++FRG++WE QRK++
Sbjct 255 ACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLK 314
Query 131 PPYKPNIQGPRDSSMFDTYAESTESSAPVI 160
PP P + G D S F+TY ES P +
Sbjct 315 PPIVPKLSGDGDISNFETYPESELDKTPSV 344
> tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=343
Score = 181 bits (458), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 79/151 (52%), Positives = 109/151 (72%), Gaps = 0/151 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT+TLCGT EY+APE + +GHG VDWW LGIL++EM+ G PPF DD P+G+Y+KI+ G
Sbjct 187 RTYTLCGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMILGYPPFFDDEPMGVYQKILGG 246
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
+I FP FD +AK L+KRLL + +RYG LK+G DVK+H++F G DW C ++ + P
Sbjct 247 RIAFPKFFDKNAKLLVKRLLTPDLAQRYGNLKNGVADVKDHRWFAGFDWNACLKKSLPSP 306
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPVIDSV 163
YKP ++G D+S F+ Y ESTE + PV ++
Sbjct 307 YKPPVKGMDDTSNFEAYPESTEQAPPVTGTM 337
> dre:561941 protein kinase, X-linked-like; K04345 protein kinase
A [EC:2.7.11.11]
Length=357
Score = 174 bits (442), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 77/139 (55%), Positives = 101/139 (72%), Gaps = 0/139 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RTWTLCGT EYLAPE I +GHG VDWWALG+L+FEMLAG PPF DD P GIY+KI+AG
Sbjct 199 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGVLIFEMLAGYPPFFDDNPFGIYQKILAG 258
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K+EFP D K LIK+ L+ + +R G +K+GA+DVK H++F+ ++WE RK++PP
Sbjct 259 KLEFPRHLDLYVKDLIKKFLVTDRERRLGNMKNGADDVKKHRWFKSVNWESVPCRKLKPP 318
Query 133 YKPNIQGPRDSSMFDTYAE 151
P + D+S FD+Y +
Sbjct 319 IVPKVSHEGDTSNFDSYPD 337
> mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP
dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 170 bits (430), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 75/140 (53%), Positives = 97/140 (69%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+KNHK+F DW YQRK+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKFKGPGDTSNFDDYEE 333
> hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase,
cAMP-dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 169 bits (429), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 75/140 (53%), Positives = 97/140 (69%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+KNHK+F DW YQRK+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKFKGPGDTSNFDDYEE 333
> xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba;
protein kinase, cAMP-dependent, catalytic, beta; K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 169 bits (429), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 76/140 (54%), Positives = 97/140 (69%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KRYG LK+G D+KNHK+F DW YQRK+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKCRGPGDTSNFDDYEE 333
> cel:ZK909.2 kin-1; protein KINase family member (kin-1); K04345
protein kinase A [EC:2.7.11.11]
Length=381
Score = 169 bits (428), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 77/140 (55%), Positives = 98/140 (70%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 224 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 283
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK++FP+ F K L+K LL + KRYG LK+G D+KNHK+F DW YQ+KI
Sbjct 284 GKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEA 343
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 344 PFLPKCRGPGDASNFDDYEE 363
> cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain
; K04345 protein kinase A [EC:2.7.11.11]
Length=392
Score = 167 bits (422), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 79/147 (53%), Positives = 99/147 (67%), Gaps = 0/147 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT+TLCGT EY+APE + +GHG VDWW LGIL++EM+ G PPF DD P+GIY+KI+AG
Sbjct 236 RTFTLCGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMVVGFPPFYDDEPMGIYQKILAG 295
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
KI FP FD + KSL+KRLL + KRYG LK G D+K HK+F D+ RK+ PP
Sbjct 296 KIFFPKYFDKNCKSLVKRLLTPDLTKRYGNLKGGVSDIKLHKWFYNYDFNSLISRKVDPP 355
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPV 159
Y P + DSS F+ Y +S E V
Sbjct 356 YIPKVNSYDDSSNFEEYPDSHEQPTTV 382
> dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate b (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 74/140 (52%), Positives = 96/140 (68%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KRYG LK+G D+K HK+F DW YQR++
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFVPKCRGPGDTSNFDDYEE 333
> dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;
protein kinase, cAMP-dependent, catalytic, beta b; K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 166 bits (419), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 73/140 (52%), Positives = 97/140 (69%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G L++G D+KNHK+F DW Y+RK+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKCRGPGDTSNFDDYEE 333
> xla:100101276 prkaca; protein kinase, cAMP-dependent, catalytic,
alpha (EC:2.7.11.1); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 165 bits (417), Expect = 8e-41, Method: Compositional matrix adjust.
Identities = 73/140 (52%), Positives = 96/140 (68%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+K HK+F DW YQ+K+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKCKGPGDTSNFDDYEE 333
> xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent,
catalytic, beta b; K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 165 bits (417), Expect = 8e-41, Method: Compositional matrix adjust.
Identities = 73/140 (52%), Positives = 96/140 (68%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+K HK+F DW YQ+K+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 314 PFIPKCKGPGDTSNFDDYEE 333
> hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; protein
kinase, cAMP-dependent, catalytic, beta (EC:2.7.11.11);
K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 73/140 (52%), Positives = 95/140 (67%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+K HK+F DW YQRK+
Sbjct 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +G D+S FD Y E
Sbjct 314 PFIPKFRGSGDTSNFDDYEE 333
> dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate a (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=352
Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 73/140 (52%), Positives = 96/140 (68%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 195 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 254
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+K HK+F DW YQ+K+
Sbjct 255 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEA 314
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P +GP D+S FD Y E
Sbjct 315 PFIPKCKGPGDTSNFDDYDE 334
> mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catalytic,
beta (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=338
Score = 163 bits (413), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 73/141 (51%), Positives = 95/141 (67%), Gaps = 0/141 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 181 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 240
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ FP+ F K L++ LL + KR+G LK+G D+K HK+F DW YQRK+
Sbjct 241 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 300
Query 132 PYKPNIQGPRDSSMFDTYAES 152
P+ P +G D+S FD Y E
Sbjct 301 PFIPKFRGSGDTSNFDDYEEE 321
> dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinase,
cAMP-dependent, catalytic, beta a; K04345 protein kinase
A [EC:2.7.11.11]
Length=395
Score = 160 bits (406), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 71/142 (50%), Positives = 96/142 (67%), Gaps = 0/142 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM AG PPF D P+ IY+KI++
Sbjct 238 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 297
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
GK+ +P+ F K L++ LL + KR+G LK+G D+KNH++F DW Y++K+
Sbjct 298 GKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDA 357
Query 132 PYKPNIQGPRDSSMFDTYAEST 153
P P +GP D+S FD Y E
Sbjct 358 PIIPKCRGPGDTSNFDEYDEEV 379
> hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent,
catalytic, gamma (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 155 bits (391), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 68/140 (48%), Positives = 93/140 (66%), Gaps = 0/140 (0%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIA 71
GRTWTLCGT EYLAPE I +G+ VDWWALG+L++EM G PPF D P+ IY+KI++
Sbjct 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVS 253
Query 72 GKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRP 131
G++ FP+ K L++ LL + KR+G L++G D+KNHK+F W Y++K+
Sbjct 254 GRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEA 313
Query 132 PYKPNIQGPRDSSMFDTYAE 151
P+ P GP D+S FD Y E
Sbjct 314 PFIPKYTGPGDASNFDDYEE 333
> bbo:BBOV_III005740 17.m07511; protein kinase domain containing
protein; K04345 protein kinase A [EC:2.7.11.11]
Length=359
Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 70/142 (49%), Positives = 100/142 (70%), Gaps = 0/142 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT+TLCGT EYLAPE + +GHG VDWW LGIL++EML G PPF ++ P+GIYKKI+
Sbjct 203 RTYTLCGTPEYLAPEILLNKGHGKAVDWWTLGILIYEMLVGYPPFYNEDPMGIYKKILDC 262
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
++ FP +D AK+L K+LL +P+KR G L GA+D+ ++F +D++ Q+K+ PP
Sbjct 263 RLVFPRNYDPDAKALTKQLLTFDPSKRIGNLHKGAKDIIASQWFAKMDFDKLLQKKLTPP 322
Query 133 YKPNIQGPRDSSMFDTYAESTE 154
Y P ++G D++ F TY +S E
Sbjct 323 YVPELKGKNDTTKFGTYPDSVE 344
> tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=333
Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 72/147 (48%), Positives = 100/147 (68%), Gaps = 0/147 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT TLCGT EY+APE + +GHG VDWW LGIL++EM+ G PPF+DD PLGIY+KI+AG
Sbjct 177 RTDTLCGTPEYIAPEVLLNKGHGKPVDWWTLGILIYEMMVGYPPFLDDDPLGIYQKILAG 236
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K FP FD AK L+K+LL + +KR+G LK+G D+K ++F + +E +K+
Sbjct 237 KFVFPKFFDKDAKVLVKKLLQADLSKRWGNLKNGVRDIKECRWFCTVVFEDLRAKKVVAR 296
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPV 159
YKP ++G D S F+ Y + + + PV
Sbjct 297 YKPTVKGMDDLSNFEAYPDEKDDAVPV 323
> cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:2.7.11.11]
Length=398
Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 67/141 (47%), Positives = 95/141 (67%), Gaps = 0/141 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT+T+CGT +YLAPES+ R GH VDWWALGIL++EM+ G+PPF T IY II
Sbjct 241 RTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEH 300
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K++FP F+ +AK L+K+LL + +R GC+K+G +DVK+HK+F ++W+ ++ PP
Sbjct 301 KLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPP 360
Query 133 YKPNIQGPRDSSMFDTYAEST 153
P + P D+ FD Y E T
Sbjct 361 IVPTLYHPGDTGNFDDYEEDT 381
> pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase
catalytic subunit; K04345 protein kinase A [EC:2.7.11.11]
Length=342
Score = 146 bits (368), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 70/154 (45%), Positives = 93/154 (60%), Gaps = 4/154 (2%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT+TLCGT EY+APE + GHG DWW LGI ++E+L G PPF + PL IY+KI+ G
Sbjct 186 RTYTLCGTPEYIAPEILLNVGHGKAADWWTLGIFIYEILVGCPPFYANEPLLIYQKILEG 245
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
I FP D + K L+K+LL H+ KRYG LK GA++VK H +F IDW + + P
Sbjct 246 IIYFPKFLDNNCKHLMKKLLSHDLTKRYGNLKKGAQNVKEHPWFSNIDWVNLLNKNVEVP 305
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPVIDSVTQQ 166
YKP + DSS F E + + D +T +
Sbjct 306 YKPKYKNIFDSSNF----ERVQEDLTIADKITNE 335
> dre:566430 cGMP dependent protein kinase I
Length=528
Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 65/160 (40%), Positives = 96/160 (60%), Gaps = 2/160 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + G +TWT CGT EY+APE I +GH + D+W+LGIL++E+L G PPF
Sbjct 359 DFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGP 418
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
P+ Y I+ G IEFP +A +LIK+L P++R G LK+G +D++ HK+F G
Sbjct 419 DPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEG 478
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTYAESTESSAP 158
+WE + + PP P++ P D+S FD++ E E P
Sbjct 479 FNWEGLRKGTLIPPIIPDVASPTDTSNFDSFPEDNEDPPP 518
> mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b;
protein kinase, cGMP-dependent, type I (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 64/160 (40%), Positives = 97/160 (60%), Gaps = 2/160 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + G +TWT CGT EY+APE I +GH + D+W+LGIL++E+L G PPF
Sbjct 502 DFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGP 561
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
P+ Y I+ G IEFP +A +LIK+L P++R G LK+G +D++ HK+F G
Sbjct 562 DPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEG 621
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTYAESTESSAP 158
+WE + + PP P++ P D+S FD++ E ++ P
Sbjct 622 FNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPP 661
> cel:Y47D3A.16 rsks-1; RSK-pSeventy (RSK-p70 kinase) homolog
family member (rsks-1); K04688 p70 ribosomal S6 kinase [EC:2.7.11.1]
Length=580
Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 61/135 (45%), Positives = 84/135 (62%), Gaps = 0/135 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
+T T CGT EY+APE + R GHG VDWW+LG L+F+ML G PPF + KI+ G
Sbjct 241 KTHTFCGTIEYMAPEILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKG 300
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
++ PA A+ LIK+LL + R G AE++K+H FF+ DW L Y R++ P
Sbjct 301 RLTLPAYLSNEARDLIKKLLKRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAP 360
Query 133 YKPNIQGPRDSSMFD 147
+KPNI+ D+S+FD
Sbjct 361 FKPNIENDEDTSLFD 375
> sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=397
Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 61/139 (43%), Positives = 90/139 (64%), Gaps = 1/139 (0%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T+TLCGT +Y+APE ++ + + +DWW+ GIL++EMLAG PF D + Y+KI+ +
Sbjct 239 TYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAE 298
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPPY 133
+ FP F+ K L+ RL+ + ++R G L++G EDVKNH +F+ + WE R I PY
Sbjct 299 LRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPY 358
Query 134 KPNI-QGPRDSSMFDTYAE 151
+P I QG D+S FD Y E
Sbjct 359 EPPIQQGQGDTSQFDKYPE 377
> hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK,
PKG, PRKG1B, PRKGR1B, cGKI-BETA, cGKI-alpha; protein kinase,
cGMP-dependent, type I (EC:2.7.11.12); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 64/160 (40%), Positives = 96/160 (60%), Gaps = 2/160 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + G +TWT CGT EY+APE I +GH + D+W+LGIL++E+L G PPF
Sbjct 502 DFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGP 561
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
P+ Y I+ G IEFP +A +LIK+L P++R G LK+G +D++ HK+F G
Sbjct 562 DPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEG 621
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTYAESTESSAP 158
+WE + + PP P++ P D+S FD++ E + P
Sbjct 622 FNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPP 661
> dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,
cGMP-dependent, type Ia (EC:2.7.11.1); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=667
Score = 135 bits (341), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 64/160 (40%), Positives = 95/160 (59%), Gaps = 2/160 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + G +TWT CGT EY+APE I +GH + D+W+LGIL++E+L G PPF
Sbjct 498 DFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGP 557
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
P+ Y I+ G IEFP +A +LIK+L P++R G LK+G +D++ HK+F G
Sbjct 558 DPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDTPSERLGNLKNGVKDIQKHKWFEG 617
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTYAESTESSAP 158
+W+ + + PP PN+ D+S FD++ E E P
Sbjct 618 FNWDGLRKGTLMPPIIPNVTSSTDTSNFDSFPEDNEDPPP 657
> tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein
kinase A [EC:2.7.11.11]
Length=352
Score = 135 bits (340), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 61/123 (49%), Positives = 85/123 (69%), Gaps = 0/123 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT TLCGT EY++PE I G+G VD+W LGIL++EML G PPF D+TP +Y KI+
Sbjct 199 RTHTLCGTPEYMSPEIILHLGYGKAVDFWTLGILIYEMLVGYPPFYDETPYNLYDKILKC 258
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K++FP+ +D AK L RLL+ +P+KR+G L G ED+K K+F +D+ ++ +RPP
Sbjct 259 KLKFPSFYDEDAKYLTSRLLVTDPSKRFGNLHKGIEDIKKCKWFAAMDFNALLEKDLRPP 318
Query 133 YKP 135
Y P
Sbjct 319 YIP 321
> dre:100125912 prkg2; protein kinase, cGMP-dependent, type II
(EC:2.7.11.1); K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=768
Score = 135 bits (339), Expect = 8e-32, Method: Compositional matrix adjust.
Identities = 65/151 (43%), Positives = 89/151 (58%), Gaps = 2/151 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + C RTWT CGT EY+APE I +GHGL VD+W+LGIL+FE+L G PPF
Sbjct 600 DFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHGLSVDFWSLGILIFELLTGSPPFTGS 659
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
+ IY I+ G K++FP LI++L P++R G LK+G D+K H++F G
Sbjct 660 DQMIIYTFILKGIEKMDFPKKITKRPGDLIRKLCRQNPSERLGNLKNGITDIKKHRWFTG 719
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTY 149
W R + P K ++GP D S FD+Y
Sbjct 720 FSWSGLKARNLISPLKREVKGPTDHSYFDSY 750
> dre:571965 protein kinase N2-like; K06071 protein kinase N [EC:2.7.11.13]
Length=970
Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 64/152 (42%), Positives = 88/152 (57%), Gaps = 3/152 (1%)
Query 9 GCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKK 68
G RT T CGT E+LAPE +T + VDWW LG+L+FEML G PF D ++
Sbjct 795 GYRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDS 854
Query 69 IIAGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRK 128
I+ ++ +P + A S+++RLL P +R G + AEDVK H FFR IDW+ +K
Sbjct 855 IVNDEVRYPRVLSTEAISIMRRLLRRNPERRLGAAERDAEDVKKHLFFRDIDWDGLLAKK 914
Query 129 IRPPYKPNIQGPRDSSMFDTYAESTESSAPVI 160
++PP+ P IQ D S FD + S APV+
Sbjct 915 VKPPFVPTIQCSSDVSNFD---DEFTSEAPVL 943
> sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=380
Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 61/139 (43%), Positives = 88/139 (63%), Gaps = 1/139 (0%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
TWTLCGT +Y+APE IT + + VDWW+LG+L++EMLAG PF D TP+ Y+KI+ GK
Sbjct 222 TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK 281
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPPY 133
+ +P F L+ +L+ + +R G L+ G+ D+K H +F + WE + I PY
Sbjct 282 VVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPY 341
Query 134 KPNI-QGPRDSSMFDTYAE 151
+P I G D+S+FD Y E
Sbjct 342 EPPITSGIGDTSLFDQYPE 360
> hsa:5586 PKN2, MGC150606, MGC71074, PAK2, PRK2, PRKCL2, PRO2042,
Pak-2; protein kinase N2 (EC:2.7.11.13); K06071 protein
kinase N [EC:2.7.11.13]
Length=984
Score = 132 bits (331), Expect = 8e-31, Method: Compositional matrix adjust.
Identities = 62/152 (40%), Positives = 87/152 (57%), Gaps = 3/152 (1%)
Query 9 GCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKK 68
G RT T CGT E+LAPE +T + VDWW LG+L++EML G PF D ++
Sbjct 809 GYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDS 868
Query 69 IIAGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRK 128
I+ ++ +P A S+++RLL P +R G + AEDVK H FFR IDW +K
Sbjct 869 IVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKK 928
Query 129 IRPPYKPNIQGPRDSSMFDTYAESTESSAPVI 160
++PP+ P I+G D S FD + S AP++
Sbjct 929 VKPPFIPTIRGREDVSNFD---DEFTSEAPIL 957
> sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase
A [EC:2.7.11.11]
Length=398
Score = 131 bits (330), Expect = 8e-31, Method: Compositional matrix adjust.
Identities = 59/139 (42%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T+TLCGT +Y+APE ++ + + VDWW+ G+L++EMLAG PF + + Y+ I+ +
Sbjct 240 TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAE 299
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPPY 133
++FP F A+ L+K+L+ + ++R G L++G+EDVKNH +F + WE R I PY
Sbjct 300 LKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPY 359
Query 134 KPNI-QGPRDSSMFDTYAE 151
+P I QG D+S FD Y E
Sbjct 360 EPPIQQGQGDTSQFDRYPE 378
> xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent,
type II (EC:2.7.11.1); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=783
Score = 130 bits (327), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 63/139 (45%), Positives = 83/139 (59%), Gaps = 2/139 (1%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
+TWT CGT EY+APE I +GH VD+W+LGILL+E+L G PPF + IY I+ G
Sbjct 627 KTWTFCGTPEYVAPEVILNKGHSFSVDFWSLGILLYELLTGNPPFTGPDQMIIYNLILQG 686
Query 73 --KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIR 130
KIEF + LI RL P +R G +K+G D+K H++F G +WE R +
Sbjct 687 IEKIEFCKNITKRPEDLICRLCRQNPAERLGYMKNGIADIKKHRWFNGFNWEGLNTRSLP 746
Query 131 PPYKPNIQGPRDSSMFDTY 149
P KP ++GP D S FD Y
Sbjct 747 SPLKPKLKGPTDHSHFDIY 765
> mmu:109333 Pkn2, 6030436C20Rik, AI507382, PRK2, Prkcl2, Stk7;
protein kinase N2 (EC:2.7.11.13); K06071 protein kinase N
[EC:2.7.11.13]
Length=983
Score = 129 bits (324), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 61/152 (40%), Positives = 86/152 (56%), Gaps = 3/152 (1%)
Query 9 GCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKK 68
G RT T CGT E+LAPE +T + VDWW LG+L++EML G PF D ++
Sbjct 808 GYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDS 867
Query 69 IIAGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRK 128
I+ ++ +P A S+++RLL P +R G + AEDVK H FFR DW +K
Sbjct 868 IVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKK 927
Query 129 IRPPYKPNIQGPRDSSMFDTYAESTESSAPVI 160
++PP+ P I+G D S FD + S AP++
Sbjct 928 VKPPFVPTIRGREDVSNFD---DEFTSEAPIL 956
> dre:100332055 prkce; protein kinase C, epsilon
Length=795
Score = 129 bits (324), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 63/156 (40%), Positives = 94/156 (60%), Gaps = 3/156 (1%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T T CGT +Y+APE + +G VDWWALG+L++EM+AG+PPF D +++ I+
Sbjct 622 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 681
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGC-LKDGAED-VKNHKFFRGIDWELCYQRKIRP 131
+ +P A S++K + P+KR GC + G ED +K H FF+ IDW L QRK++P
Sbjct 682 VLYPVWLSKEAVSILKAFMTKSPSKRLGCVVSQGLEDAIKVHPFFKDIDWVLLEQRKVKP 741
Query 132 PYKPNIQGPRDSSMFDT-YAESTESSAPVIDSVTQQ 166
P+KP I+ RD + FD + PV D++ +Q
Sbjct 742 PFKPRIKTKRDVNNFDQDFTREEPVLTPVEDAIIKQ 777
> tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11.13)
Length=951
Score = 128 bits (322), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 62/162 (38%), Positives = 97/162 (59%), Gaps = 6/162 (3%)
Query 6 LREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGI 65
+ + C R+ LCGT EYLAPE ++++GHG VDWW+LG L++EML G PPF +
Sbjct 608 VEDNCSARS--LCGTPEYLAPEILSQQGHGKAVDWWSLGALIYEMLTGLPPFYTGDRERL 665
Query 66 YKKIIAGKIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCY 125
++ I + ++++P+ +A L++ L +PN+R G AE++K H FF IDWE
Sbjct 666 FENIRSSELQYPSYMSRAAVHLLRGLFQRDPNRRLGGGPGDAEEIKRHPFFGRIDWEALQ 725
Query 126 QRKIRPPYKPNIQGPRDSSMFDTYAESTESSAPVIDSVTQQA 167
+++RPP++P +Q P D FD PVI+S Q++
Sbjct 726 AKRMRPPFRPRLQSPTDVQYFDNEF----VKLPVINSEVQES 763
> hsa:5581 PRKCE, MGC125656, MGC125657, PKCE, nPKC-epsilon; protein
kinase C, epsilon (EC:2.7.11.13); K06068 novel protein
kinase C [EC:2.7.11.13]
Length=737
Score = 128 bits (322), Expect = 9e-30, Method: Compositional matrix adjust.
Identities = 59/152 (38%), Positives = 91/152 (59%), Gaps = 2/152 (1%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T T CGT +Y+APE + +G VDWWALG+L++EM+AG+PPF D +++ I+
Sbjct 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCL--KDGAEDVKNHKFFRGIDWELCYQRKIRP 131
+ +P A S++K + P+KR GC+ ++G + +K H FF+ IDW L Q+KI+P
Sbjct 624 VLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKP 683
Query 132 PYKPNIQGPRDSSMFDTYAESTESSAPVIDSV 163
P+KP I+ RD + FD E ++D
Sbjct 684 PFKPRIKTKRDVNNFDQDFTREEPVLTLVDEA 715
> mmu:18754 Prkce, 5830406C15Rik, PKC[e], PKCepsilon, Pkce, R75156;
protein kinase C, epsilon (EC:2.7.11.13); K06068 novel
protein kinase C [EC:2.7.11.13]
Length=737
Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 59/152 (38%), Positives = 91/152 (59%), Gaps = 2/152 (1%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T T CGT +Y+APE + +G VDWWALG+L++EM+AG+PPF D +++ I+
Sbjct 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCL--KDGAEDVKNHKFFRGIDWELCYQRKIRP 131
+ +P A S++K + P+KR GC+ ++G + +K H FF+ IDW L Q+KI+P
Sbjct 624 VLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKP 683
Query 132 PYKPNIQGPRDSSMFDTYAESTESSAPVIDSV 163
P+KP I+ RD + FD E ++D
Sbjct 684 PFKPRIKTKRDVNNFDQDFTREEPILTLVDEA 715
> dre:560549 akt3a, akt3, si:ch211-221n23.2; v-akt murine thymoma
viral oncogene homolog 3a (EC:2.7.11.1); K04456 RAC serine/threonine-protein
kinase [EC:2.7.11.1]
Length=479
Score = 128 bits (321), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 57/132 (43%), Positives = 81/132 (61%), Gaps = 0/132 (0%)
Query 16 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIE 75
T CGT EYLAPE + +G VDWW LG++++EM+ GR PF + +++ I+ I+
Sbjct 305 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIK 364
Query 76 FPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPPYKP 135
FP AKSL+ LLI +PNKR G D A+++ H FF GIDW+ Y +K+ PP+KP
Sbjct 365 FPRTLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTGIDWQDVYDKKLIPPFKP 424
Query 136 NIQGPRDSSMFD 147
+ D+ FD
Sbjct 425 QVSSETDTRYFD 436
> hsa:6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1; ribosomal protein
S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1); K04373 p90
ribosomal S6 kinase [EC:2.7.11.1]
Length=744
Score = 127 bits (318), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 58/149 (38%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
+ ++ CGT EY+APE + R+GH DWW+ G+L+FEML G PF I+
Sbjct 227 KAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 286
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K+ P A+SL++ L P R G DGAE++K H F+ IDW Y+R+I+PP
Sbjct 287 KLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPP 346
Query 133 YKPNIQGPRDSSMFDT-YAESTESSAPVI 160
+KP + P D+ FDT + T +P I
Sbjct 347 FKPAVAQPDDTFYFDTEFTSRTPKDSPGI 375
Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVD---DTPLGIYKK 68
G T C T ++APE + R+G+ D W+LGILL+ MLAG PF + DTP I +
Sbjct 578 GLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTR 637
Query 69 IIAGKIEFPA----LFDCSAKSLIKRLLIHEPNKR 99
I +GK +AK L+ ++L +P++R
Sbjct 638 IGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQR 672
> dre:556339 protein kinase, cGMP-dependent, type II-like; K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=730
Score = 126 bits (317), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 2/151 (1%)
Query 1 DYRLRLREGCVGRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDD 60
D+ + G +TWT CGT EY+APE I +GH D W+LGIL+FE+L G PPF
Sbjct 562 DFGFAKKIGLGKKTWTFCGTPEYVAPEVIMNKGHDFGADCWSLGILIFELLIGSPPFTGS 621
Query 61 TPLGIYKKIIAG--KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRG 118
P+ IY ++ G K++ P + LI+RL P +R G K+G D+K HK+F+G
Sbjct 622 DPIRIYTMVLHGIEKVDIPKRISKRPEDLIRRLCKLNPAERLGNKKNGIIDIKKHKWFQG 681
Query 119 IDWELCYQRKIRPPYKPNIQGPRDSSMFDTY 149
+WE +RK+ P + ++GP D S FD +
Sbjct 682 FNWEGLRRRKLMSPLRRELKGPLDHSYFDMF 712
> mmu:20111 Rps6ka1, Rsk1, p90rsk, rsk; ribosomal protein S6 kinase
polypeptide 1 (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase
[EC:2.7.11.1]
Length=735
Score = 126 bits (316), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 58/149 (38%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
+ ++ CGT EY+APE + R+GH DWW+ G+L+FEML G PF I+
Sbjct 218 KAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 277
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K+ P A+SL++ L P R G DGAE++K H F+ IDW Y+R+I+PP
Sbjct 278 KLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPP 337
Query 133 YKPNIQGPRDSSMFDT-YAESTESSAPVI 160
+KP + P D+ FDT + T +P I
Sbjct 338 FKPAVAQPDDTFYFDTEFTSRTPRDSPGI 366
Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVD---DTPLGIYKK 68
G T C T ++APE + R+G+ D W+LGILL+ MLAG PF + DTP I +
Sbjct 569 GLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTR 628
Query 69 IIAGKIEFPA----LFDCSAKSLIKRLLIHEPNKR 99
I +GK +AK L+ ++L +P++R
Sbjct 629 IGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQR 663
> xla:399376 rps6ka3, MGC82193, S6KII, p90, rsk, rsk2; ribosomal
protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1); K04373
p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=737
Score = 126 bits (316), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 61/159 (38%), Positives = 84/159 (52%), Gaps = 2/159 (1%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
+ ++ CGT EY+APE + RRGH DWW+ G+L+FEML G PF I+
Sbjct 221 KAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKA 280
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K+ P A+SL++ L P R G DG E++K H FF IDW ++R+I+PP
Sbjct 281 KLGMPQFLTPEAQSLLRMLFKRNPTNRLGAGPDGVEEIKRHPFFVTIDWNKLFRREIQPP 340
Query 133 YKPNIQGPRDSSMFD-TYAESTESSAPVI-DSVTQQALF 169
+KP GP D+ FD + T +P I S LF
Sbjct 341 FKPATGGPEDTFYFDPEFTAKTPKDSPGIPASANAHQLF 379
Score = 58.9 bits (141), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVD---DTPLGIYKK 68
G T C T ++APE + R+G+ D W+LG+LL+ ML G PF + DTP I +
Sbjct 569 GLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPEDTPEEILAR 628
Query 69 IIAGKIEFPALFDCS----AKSLIKRLLIHEPNKR 99
I +GK + S AK L+ ++L +P++R
Sbjct 629 IGSGKFSLSGGYWNSVSDIAKDLVSKMLHVDPHQR 663
> dre:571285 ribosomal protein S6 kinase, polypeptide 2-like;
K04373 p90 ribosomal S6 kinase [EC:2.7.11.1]
Length=733
Score = 126 bits (316), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 61/159 (38%), Positives = 85/159 (53%), Gaps = 2/159 (1%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
R ++ CGT EY+APE + RRGH DWW+ G+L+FEML G PF I+
Sbjct 215 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
K+ P +SL++ L P+ R G DG E++K H FF IDW Y+R+I+PP
Sbjct 275 KLGMPQFLSPEVQSLLRALFKRNPSNRLGAGPDGVEEIKRHIFFATIDWNKLYRREIKPP 334
Query 133 YKPNIQGPRDSSMFD-TYAESTESSAP-VIDSVTQQALF 169
+KP + P D+ FD + T + +P V S LF
Sbjct 335 FKPAVGRPEDTFHFDPEFTSRTPTDSPGVPASANAHQLF 373
Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query 12 GRTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFV---DDTPLGIYKK 68
G T C T ++APE + ++G+ D W+LGILL+ MLAG PF DDTP I +
Sbjct 566 GLLMTPCYTANFVAPEVLKKQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILAR 625
Query 69 IIAGKIEFPA----LFDCSAKSLIKRLLIHEPNKR 99
I +GK +AK ++ ++L +P++R
Sbjct 626 IGSGKFALSGGNWDTVSDAAKDIVTKMLHVDPHQR 660
> cel:E01H11.1 pkc-2; Protein Kinase C family member (pkc-2);
K02677 classical protein kinase C [EC:2.7.11.13]
Length=725
Score = 125 bits (315), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 62/138 (44%), Positives = 83/138 (60%), Gaps = 3/138 (2%)
Query 14 TWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGK 73
T T CGT +Y+APE I + +G VDWWA G+LLFEMLAG+PPF + ++ I
Sbjct 549 TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHN 608
Query 74 IEFPALFDCSAKSLIKRLLIHEPNKRYGCLKD---GAEDVKNHKFFRGIDWELCYQRKIR 130
+ +P A SL K LLI P+KR GC D + D+K H FFR IDW R+I+
Sbjct 609 VSYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQ 668
Query 131 PPYKPNIQGPRDSSMFDT 148
PP+KP ++ D+S FD+
Sbjct 669 PPFKPKLKSADDTSNFDS 686
> dre:560840 hypothetical LOC560840; K06071 protein kinase N [EC:2.7.11.13]
Length=948
Score = 125 bits (315), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 60/148 (40%), Positives = 83/148 (56%), Gaps = 3/148 (2%)
Query 13 RTWTLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAG 72
RT T CGT E+LAPE +T + VDWW LG+L++EML G PF D ++ I+
Sbjct 777 RTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVND 836
Query 73 KIEFPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPP 132
++ +P A +++RLL P +R G + AEDVK FFR +DWE RK+ PP
Sbjct 837 EVRYPRFLSAEAIGIMRRLLRRNPERRLGSSEKDAEDVKKQPFFRNMDWEALLLRKLPPP 896
Query 133 YKPNIQGPRDSSMFDTYAESTESSAPVI 160
+ P+I G D S FD E + AP +
Sbjct 897 FIPSIGGKEDVSNFD---EEFTTEAPTL 921
> mmu:23797 Akt3, AI851531, D930002M15Rik, Nmf350; thymoma viral
proto-oncogene 3 (EC:2.7.11.1); K04456 RAC serine/threonine-protein
kinase [EC:2.7.11.1]
Length=479
Score = 125 bits (315), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 55/132 (41%), Positives = 81/132 (61%), Gaps = 0/132 (0%)
Query 16 TLCGTHEYLAPESITRRGHGLQVDWWALGILLFEMLAGRPPFVDDTPLGIYKKIIAGKIE 75
T CGT EYLAPE + +G VDWW LG++++EM+ GR PF + +++ I+ I+
Sbjct 305 TFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIK 364
Query 76 FPALFDCSAKSLIKRLLIHEPNKRYGCLKDGAEDVKNHKFFRGIDWELCYQRKIRPPYKP 135
FP AKSL+ LLI +PNKR G D A+++ H FF G++W+ Y +K+ PP+KP
Sbjct 365 FPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKP 424
Query 136 NIQGPRDSSMFD 147
+ D+ FD
Sbjct 425 QVTSETDTRYFD 436
Lambda K H
0.323 0.142 0.458
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4222647260
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40