bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0394_orf3
Length=172
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_112100 Ca2+-ATPase (EC:3.6.3.8); K05850 Ca2+ transp... 252 4e-67
tgo:TGME49_033770 Ca2+-ATPase, putative (EC:3.6.3.8); K05850 C... 174 1e-43
hsa:493 ATP2B4, ATP2B2, DKFZp686G08106, DKFZp686M088, MXRA1, P... 112 5e-25
xla:446855 atp2b4, MGC80772, atp2b2, atp2b3, mxra1, pmca4, pmc... 112 8e-25
hsa:492 ATP2B3, PMCA3, PMCA3a; ATPase, Ca++ transporting, plas... 111 1e-24
mmu:381290 Atp2b4, MGC129362, MGC129363, PMCA4; ATPase, Ca++ t... 110 2e-24
mmu:320707 Atp2b3, 6430519O13Rik, Pmca3; ATPase, Ca++ transpor... 110 3e-24
dre:436745 atp2b3a, atp2b3, pmca3a, zgc:92885; ATPase, Ca++ tr... 110 3e-24
mmu:11941 Atp2b2, D6Abb2e, PMCA2, Tmy, dfw, jog, wms, wri; ATP... 108 1e-23
hsa:491 ATP2B2, PMCA2, PMCA2a, PMCA2i; ATPase, Ca++ transporti... 108 1e-23
dre:557430 atp2b2; ATPase, Ca++ transporting, plasma membrane ... 106 3e-23
dre:378746 atp2b1a, pmca1, pmca1a, sb:cb801, si:dkey-18o7.1, w... 105 7e-23
cel:Y67D8C.10 mca-3; Membrane Calcium ATPase family member (mc... 104 2e-22
dre:558525 atp2b3b; ATPase, Ca++ transporting, plasma membrane... 104 2e-22
hsa:490 ATP2B1, PMCA1, PMCA1kb; ATPase, Ca++ transporting, pla... 103 3e-22
mmu:67972 Atp2b1, 2810442I22Rik, E130111D10Rik, Pmca1; ATPase,... 103 4e-22
dre:561190 atp2b1b; ATPase, Ca++ transporting, plasma membrane 1b 102 8e-22
cel:R05C11.3 ATPase; hypothetical protein; K01537 Ca2+-transpo... 100 3e-21
cel:W09C2.3 mca-1; Membrane Calcium ATPase family member (mca-1) 100 3e-21
sce:YGL006W PMC1; Pmc1p (EC:3.6.3.8); K01537 Ca2+-transporting... 87.0 3e-17
ath:AT4G37640 ACA2; ACA2 (CALCIUM ATPASE 2); calcium ion trans... 82.8 6e-16
ath:AT2G22950 calcium-transporting ATPase, plasma membrane-typ... 82.0 1e-15
ath:AT4G29900 ACA10; ACA10 (AUTOINHIBITED CA(2+)-ATPASE 10); c... 81.6 1e-15
ath:AT2G41560 ACA4; ACA4 (AUTO-INHIBITED CA(2+)-ATPASE, ISOFOR... 81.3 2e-15
ath:AT5G57110 ACA8; ACA8 (AUTOINHIBITED CA2+ -ATPASE, ISOFORM ... 78.6 9e-15
ath:AT3G22910 calcium-transporting ATPase, plasma membrane-typ... 73.9 2e-13
ath:AT3G21180 ACA9; ACA9 (AUTOINHIBITED CA(2+)-ATPASE 9); calc... 73.9 2e-13
ath:AT3G57330 ACA11; ACA11 (autoinhibited Ca2+-ATPase 11); cal... 73.6 3e-13
pfa:PFA_0310c calcium-transporting ATPase, putative (EC:3.6.3.... 72.8 5e-13
hsa:487 ATP2A1, ATP2A, SERCA1; ATPase, Ca++ transporting, card... 71.2 1e-12
sce:YDR039C ENA2; Ena2p (EC:3.6.3.7 3.6.3.12); K01536 Na+-expo... 71.2 2e-12
sce:YDR038C ENA5; Ena5p (EC:3.6.3.7) 71.2 2e-12
sce:YDR040C ENA1, HOR6, PMR2; Ena1p (EC:3.6.3.7) 71.2 2e-12
mmu:11937 Atp2a1, SERCA1; ATPase, Ca++ transporting, cardiac m... 70.1 3e-12
ath:AT3G63380 calcium-transporting ATPase, plasma membrane-typ... 69.3 6e-12
tgo:TGME49_030420 calcium-transporting ATPase, putative (EC:3.... 69.3 6e-12
xla:495440 atp2a3, serca3; ATPase, Ca++ transporting, ubiquito... 66.6 4e-11
hsa:489 ATP2A3, SERCA3; ATPase, Ca++ transporting, ubiquitous ... 66.6 4e-11
ath:AT4G00900 ECA2; ECA2 (ER-TYPE CA2+-ATPASE 2); calcium-tran... 66.2 6e-11
cel:K11D9.2 sca-1; SERCA (Sarco-Endoplasmic Reticulum Calcium ... 64.3 2e-10
xla:380096 atp2a2, MGC52615, atp2b, ca-p60a, dar, serca2; ATPa... 64.3 2e-10
mmu:53313 Atp2a3, SERCA3b, Serca3; ATPase, Ca++ transporting, ... 63.5 3e-10
xla:446229 atp2a1, atp2a, atp2a2, serca1; ATPase, Ca++ transpo... 62.0 9e-10
tpv:TP02_0524 calcium-transporting ATPase; K01537 Ca2+-transpo... 62.0 9e-10
dre:568265 atp2a2b, SERCA2, fb51e04, fb80c02, si:dkey-83d9.6, ... 61.6 1e-09
ath:AT1G59820 ALA3; ALA3 (Aminophospholipid ATPase3); ATPase, ... 61.6 1e-09
ath:AT5G44240 haloacid dehalogenase-like hydrolase family prot... 60.8 2e-09
cpv:cgd7_4190 cation-transporting P-type ATpase with 11 or mor... 60.5 3e-09
dre:494489 atp2a1l, zgc:154094; ATPase, Ca++ transporting, car... 60.5 3e-09
dre:64613 atp1a1a.2, atp1a1l2, atp[a]1A2b, cb703, zgc:110523; ... 60.5 3e-09
> tgo:TGME49_112100 Ca2+-ATPase (EC:3.6.3.8); K05850 Ca2+ transporting
ATPase, plasma membrane [EC:3.6.3.8]
Length=1822
Score = 252 bits (644), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 116/172 (67%), Positives = 141/172 (81%), Gaps = 0/172 (0%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTIC+AYR+ D P+W+E+ AP Q F+ E L CLGI GI+DPVR+EVPGAV +C
Sbjct 1202 RTICLAYRDIDPEREPDWRERCAAPHQMFMKGETQLTCLGIAGIEDPVRDEVPGAVAQCQ 1261
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ITAKAIAK+C IF+EE G LAMLGP+FT+ +GGVVCQ C+T +C C
Sbjct 1262 RAGIKVRMVTGDNIITAKAIAKRCEIFHEESGGLAMLGPDFTRAIGGVVCQTCQTEVCAC 1321
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALKQ 172
ATDAKTAE + K LRVDV+ ++DAF++IW RL+VLARSQPSDKY LVTALKQ
Sbjct 1322 ATDAKTAEEQNKPLRVDVVRDLDAFDKIWTRLEVLARSQPSDKYALVTALKQ 1373
> tgo:TGME49_033770 Ca2+-ATPase, putative (EC:3.6.3.8); K05850
Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Length=1404
Score = 174 bits (441), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 92/173 (53%), Positives = 108/173 (62%), Gaps = 3/173 (1%)
Query 1 RTICIAYREFDVSEV-PNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERC 59
RTIC+AY++ E W E + F E L CL I GI+DPVR EVP AV C
Sbjct 854 RTICLAYKDIAADEGDTTWAEA--SELHPFKKMELGLTCLAIVGIRDPVRPEVPAAVLAC 911
Query 60 HQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICG 119
AGI VRMVTGDN+ TAK IA KC+I++ E+ LAM GPEF L+GGVVC CR A+C
Sbjct 912 QNAGIKVRMVTGDNIETAKQIAVKCNIYHPEKNGLAMTGPEFNALIGGVVCSGCRLAMCD 971
Query 120 CATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALKQ 172
C A GK +RVDVI N +AF I L+VLARSQP DKY LV LK+
Sbjct 972 CPRHPAEERATGKKMRVDVIANPEAFNEIADNLEVLARSQPMDKYALVVGLKE 1024
> hsa:493 ATP2B4, ATP2B2, DKFZp686G08106, DKFZp686M088, MXRA1,
PMCA4, PMCA4b, PMCA4x; ATPase, Ca++ transporting, plasma membrane
4 (EC:3.6.3.8); K05850 Ca2+ transporting ATPase, plasma
membrane [EC:3.6.3.8]
Length=1170
Score = 112 bits (281), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 67/170 (39%), Positives = 91/170 (53%), Gaps = 37/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTICIAYR+FD +E P+W + +L C+ + GI+DPVR EVP A+ +C
Sbjct 636 RTICIAYRDFDDTE-PSWDNENEI--------LTELTCIAVVGIEDPVRPEVPDAIAKCK 686
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
QAGI VRMVTGDN+ TA+AIA KC I L + G EF +L+
Sbjct 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRN------------- 733
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ E E + L ++IW +L+VLARS P+DK+ LV +
Sbjct 734 ----EKGEVEQEKL-----------DKIWPKLRVLARSSPTDKHTLVKGI 768
> xla:446855 atp2b4, MGC80772, atp2b2, atp2b3, mxra1, pmca4, pmca4b,
pmca4x; ATPase, Ca++ transporting, plasma membrane 4
(EC:3.6.3.8); K05850 Ca2+ transporting ATPase, plasma membrane
[EC:3.6.3.8]
Length=1208
Score = 112 bits (279), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 66/170 (38%), Positives = 89/170 (52%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTICIAYR+F +S P W + DL CL + GI+DPVR EVP A+ +C
Sbjct 673 RTICIAYRDFPMSPEPEWDNENDI--------VTDLTCLAVVGIEDPVRPEVPEAIRKCQ 724
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF + +
Sbjct 725 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCIDGKEFNRRI--------------- 769
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 770 ----HNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 806
> hsa:492 ATP2B3, PMCA3, PMCA3a; ATPase, Ca++ transporting, plasma
membrane 3 (EC:3.6.3.8); K05850 Ca2+ transporting ATPase,
plasma membrane [EC:3.6.3.8]
Length=1220
Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 63/170 (37%), Positives = 89/170 (52%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTICIAYR+F + P+W + DL C+ + GI+DPVR EVP A+ +C
Sbjct 644 RTICIAYRDFSAGQEPDWDNENEVVG--------DLTCIAVVGIEDPVRPEVPEAIRKCQ 695
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I L + G EF + +
Sbjct 696 RAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRI--------------- 740
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D ++W +L+VLARS P+DK+ LV +
Sbjct 741 ----RNEKGEIEQERLD---------KVWPKLRVLARSSPTDKHTLVKGI 777
> mmu:381290 Atp2b4, MGC129362, MGC129363, PMCA4; ATPase, Ca++
transporting, plasma membrane 4 (EC:3.6.3.8); K05850 Ca2+ transporting
ATPase, plasma membrane [EC:3.6.3.8]
Length=1205
Score = 110 bits (276), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 67/170 (39%), Positives = 93/170 (54%), Gaps = 37/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTIC+AYR+FD +E P+W + L + LIC+ + GI+DPVR EVP A+ +C
Sbjct 637 RTICLAYRDFDGTE-PSWD-----IEGEILTS---LICIAVVGIEDPVRPEVPDAIAKCK 687
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF L+
Sbjct 688 RAGITVRMVTGDNVNTARAIATKCGILTPKDDFLCLEGKEFNSLIRN------------- 734
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ E E + L ++IW +L+VLARS P+DK+ LV +
Sbjct 735 ----EKGEVEQEKL-----------DKIWPKLRVLARSSPTDKHTLVKGI 769
> mmu:320707 Atp2b3, 6430519O13Rik, Pmca3; ATPase, Ca++ transporting,
plasma membrane 3 (EC:3.6.3.8); K05850 Ca2+ transporting
ATPase, plasma membrane [EC:3.6.3.8]
Length=1220
Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 63/170 (37%), Positives = 89/170 (52%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTICIAYR+F + P+W + DL C+ + GI+DPVR EVP A+ +C
Sbjct 644 RTICIAYRDFSAIQEPDWDNENEVVG--------DLTCIAVVGIEDPVRPEVPEAIRKCQ 695
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I L + G EF + +
Sbjct 696 RAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRI--------------- 740
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D ++W +L+VLARS P+DK+ LV +
Sbjct 741 ----RNEKGEIEQERLD---------KVWPKLRVLARSSPTDKHTLVKGI 777
> dre:436745 atp2b3a, atp2b3, pmca3a, zgc:92885; ATPase, Ca++
transporting, plasma membrane 3a
Length=1176
Score = 110 bits (274), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 64/170 (37%), Positives = 93/170 (54%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTICIAYRE +P+W ++ +V+ +L C+ + GI+DPVR EVP A+ +C
Sbjct 644 RTICIAYRELPADPLPDWD------NETDIVS--NLTCITVVGIEDPVRPEVPDAIRKCQ 695
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L M G +F + +
Sbjct 696 RAGITVRMVTGDNINTARAIAAKCGIIHPGDDFLCMEGKDFNRRI--------------- 740
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 741 ----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 777
> mmu:11941 Atp2b2, D6Abb2e, PMCA2, Tmy, dfw, jog, wms, wri; ATPase,
Ca++ transporting, plasma membrane 2 (EC:3.6.3.8); K05850
Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Length=1198
Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 63/170 (37%), Positives = 90/170 (52%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTIC+AYR+F S P+W + +L C+ + GI+DPVR EVP A+ +C
Sbjct 625 RTICVAYRDFPSSPEPDWDNENDI--------LNELTCICVVGIEDPVRPEVPEAIRKCQ 676
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF + +
Sbjct 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRI--------------- 721
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 722 ----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 758
> hsa:491 ATP2B2, PMCA2, PMCA2a, PMCA2i; ATPase, Ca++ transporting,
plasma membrane 2 (EC:3.6.3.8); K05850 Ca2+ transporting
ATPase, plasma membrane [EC:3.6.3.8]
Length=1243
Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 63/170 (37%), Positives = 90/170 (52%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTIC+AYR+F S P+W + +L C+ + GI+DPVR EVP A+ +C
Sbjct 670 RTICVAYRDFPSSPEPDWDNENDI--------LNELTCICVVGIEDPVRPEVPEAIRKCQ 721
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF + +
Sbjct 722 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRI--------------- 766
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 767 ----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 803
> dre:557430 atp2b2; ATPase, Ca++ transporting, plasma membrane
2 (EC:3.6.3.8); K05850 Ca2+ transporting ATPase, plasma membrane
[EC:3.6.3.8]
Length=1253
Score = 106 bits (265), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 62/170 (36%), Positives = 92/170 (54%), Gaps = 36/170 (21%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RTIC+ YR+F PNW+++ + L DL + + GI+DPVR EVP A+++C
Sbjct 681 RTICVGYRDFPKDPEPNWEDEN-----NILT---DLTAICVVGIEDPVRPEVPDAIQKCQ 732
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF + +
Sbjct 733 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCIDGKEFNRRI--------------- 777
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D ++W +L+VLARS P+DK+ LV +
Sbjct 778 ----RNEKGEVEQERID---------KVWPKLRVLARSSPTDKHTLVKGI 814
> dre:378746 atp2b1a, pmca1, pmca1a, sb:cb801, si:dkey-18o7.1,
wu:fe47b06, wu:fi41d01; ATPase, Ca++ transporting, plasma membrane
1a (EC:3.6.3.8); K05850 Ca2+ transporting ATPase, plasma
membrane [EC:3.6.3.8]
Length=1228
Score = 105 bits (262), Expect = 7e-23, Method: Compositional matrix adjust.
Identities = 65/171 (38%), Positives = 90/171 (52%), Gaps = 37/171 (21%)
Query 1 RTICIAYREFDVSE-VPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERC 59
RTIC+AYR+F SE P+W + + L C+ + GI+DPVR EVP A+ +C
Sbjct 646 RTICLAYRDFPASEGEPDWDNEADILTR--------LTCVCVVGIEDPVRPEVPDAIRKC 697
Query 60 HQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICG 119
+AGI VRMVTGDNL TA+AIA KC I L + G EF + +
Sbjct 698 QRAGITVRMVTGDNLNTARAIATKCGILQVGDDFLCLEGKEFNRRI-------------- 743
Query 120 CATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 744 -----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 780
> cel:Y67D8C.10 mca-3; Membrane Calcium ATPase family member (mca-3);
K05850 Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Length=1137
Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 63/182 (34%), Positives = 93/182 (51%), Gaps = 48/182 (26%)
Query 1 RTICIAYREF------------DVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPV 48
RTIC+AY+++ S P+W+ ++ +V D+ + + GIQDPV
Sbjct 603 RTICVAYKDYVPSSKKTADNQIAYSSEPDWENEE------MIVG--DMTAIAVLGIQDPV 654
Query 49 REEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGV 108
R EVP A+ RC +AGI VRMVTGDN+ TA++IA C I +A+ G EF
Sbjct 655 RPEVPAAITRCQEAGITVRMVTGDNINTARSIATACGILKPGEDFIALEGKEF------- 707
Query 109 VCQNCRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVT 168
+A+ + G+ + + + IW +L+VLAR+QPSDKYVLV
Sbjct 708 --------------NARIRDENGEV-------SQEKLDLIWPKLRVLARAQPSDKYVLVK 746
Query 169 AL 170
+
Sbjct 747 GI 748
> dre:558525 atp2b3b; ATPase, Ca++ transporting, plasma membrane
3b (EC:3.6.3.8); K05850 Ca2+ transporting ATPase, plasma
membrane [EC:3.6.3.8]
Length=1174
Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 63/172 (36%), Positives = 88/172 (51%), Gaps = 40/172 (23%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAE--QDLICLGIFGIQDPVREEVPGAVER 58
RTICI YR+ P W+ + AE DL C+ + GI+DPVR EVP A+ +
Sbjct 645 RTICIGYRDLPGDPEPEWENE----------AEIVTDLTCIAVVGIEDPVRPEVPDAIRK 694
Query 59 CHQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
C +AGI VRMVTGDN+ TA+AIA KC I L + G +F + +
Sbjct 695 CQRAGITVRMVTGDNINTARAIASKCGIIQPGDDFLCLEGKDFNRRI------------- 741
Query 119 GCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 742 ------RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 778
> hsa:490 ATP2B1, PMCA1, PMCA1kb; ATPase, Ca++ transporting, plasma
membrane 1 (EC:3.6.3.8); K05850 Ca2+ transporting ATPase,
plasma membrane [EC:3.6.3.8]
Length=1176
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 61/171 (35%), Positives = 89/171 (52%), Gaps = 37/171 (21%)
Query 1 RTICIAYREFDVSEV-PNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERC 59
RTIC+A+R+F E P W + L C+ + GI+DPVR EVP A+++C
Sbjct 646 RTICLAFRDFPAGEPEPEWDNENDI--------VTGLTCIAVVGIEDPVRPEVPDAIKKC 697
Query 60 HQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICG 119
+AGI VRMVTGDN+ TA+AIA KC I + L + G +F + +
Sbjct 698 QRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI-------------- 743
Query 120 CATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 744 -----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 780
> mmu:67972 Atp2b1, 2810442I22Rik, E130111D10Rik, Pmca1; ATPase,
Ca++ transporting, plasma membrane 1 (EC:3.6.3.8); K05850
Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
Length=1220
Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 61/171 (35%), Positives = 89/171 (52%), Gaps = 37/171 (21%)
Query 1 RTICIAYREFDVSEV-PNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERC 59
RTIC+A+R+F E P W + L C+ + GI+DPVR EVP A+++C
Sbjct 646 RTICLAFRDFPAGEPEPEWDNENDV--------VTGLTCIAVVGIEDPVRPEVPEAIKKC 697
Query 60 HQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICG 119
+AGI VRMVTGDN+ TA+AIA KC I + L + G +F + +
Sbjct 698 QRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI-------------- 743
Query 120 CATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ + E + R+D +IW +L+VLARS P+DK+ LV +
Sbjct 744 -----RNEKGEIEQERID---------KIWPKLRVLARSSPTDKHTLVKGI 780
> dre:561190 atp2b1b; ATPase, Ca++ transporting, plasma membrane
1b
Length=1240
Score = 102 bits (253), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 64/171 (37%), Positives = 92/171 (53%), Gaps = 37/171 (21%)
Query 1 RTICIAYREFDVSE-VPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERC 59
RTIC+AYR+F VS+ P+W + L L C+ + GI+DPVR EVP A+++C
Sbjct 655 RTICLAYRDFLVSDGEPDWNNEG-----DILTG---LTCICVVGIEDPVRPEVPDAIKKC 706
Query 60 HQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICG 119
+AGI VRMVTGDN+ TA+AIA KC I + L + G EF + +
Sbjct 707 QRAGITVRMVTGDNINTARAIATKCGILHIGDDFLCLEGKEFNRRI-------------- 752
Query 120 CATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ E + R+D ++W +L+VLARS P+DK+ LV +
Sbjct 753 -----RNELGEIEQERLD---------KVWPKLRVLARSSPTDKHTLVKGI 789
> cel:R05C11.3 ATPase; hypothetical protein; K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1158
Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 56/133 (42%), Positives = 75/133 (56%), Gaps = 28/133 (21%)
Query 38 CLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAML 97
+ + GIQDPVR EVP A+ +C +AGI VRMVTGDN+ TA++IA +C I LA+
Sbjct 637 VIAVMGIQDPVRPEVPAAIAKCQKAGITVRMVTGDNINTARSIATQCGIMQPGGDFLALE 696
Query 98 GPEFTQLVGGVVCQNCRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLAR 157
G EF +A+ +A+GK N F+ IW +L+VLAR
Sbjct 697 GKEF---------------------NARIRDADGKV-------NQQKFDAIWPKLRVLAR 728
Query 158 SQPSDKYVLVTAL 170
+QPSDKYVLV +
Sbjct 729 AQPSDKYVLVKGI 741
> cel:W09C2.3 mca-1; Membrane Calcium ATPase family member (mca-1)
Length=1252
Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 63/178 (35%), Positives = 89/178 (50%), Gaps = 37/178 (20%)
Query 1 RTICIAY--------REFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEV 52
RTIC+AY R+ + +E+ + E Q+ + I GIQDPVR EV
Sbjct 657 RTICVAYKTIIKKGTRDVEKTEI-EFAEDSDIDWDDEDAMYQNFTGIAICGIQDPVRPEV 715
Query 53 PGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQN 112
P A+ +C +AGI VRMVTGDN++TA+AIA C I LA+ G EF + +
Sbjct 716 PVAISKCKKAGITVRMVTGDNIMTARAIAMSCKILEPGEDFLALEGKEFNERIRD----- 770
Query 113 CRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTAL 170
+ K ++A+ + IW RL+VLAR+QP+DKY LV +
Sbjct 771 ---------ENGKVSQAK--------------LDEIWPRLRVLARAQPADKYTLVKGI 805
> sce:YGL006W PMC1; Pmc1p (EC:3.6.3.8); K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1173
Score = 87.0 bits (214), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 65/182 (35%), Positives = 88/182 (48%), Gaps = 49/182 (26%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDL--------ICLGIFGIQDPVREEV 52
R I +A+++F E +W +Q K S +A DL I G+ GIQDP+R V
Sbjct 687 RAISVAHKDF--CECDSWPPEQLRDKDSPNIAALDLLFNSQKGLILDGLLGIQDPLRAGV 744
Query 53 PGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEE---RGDLAMLGPEFTQLVGGVV 109
+V++C +AG+ VRMVTGDN++TAKAIA+ C I + + AM G EF +L
Sbjct 745 RESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRKLT---- 800
Query 110 CQNCRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTA 169
KN R+ RI L+VLARS P DK +LV
Sbjct 801 ----------------------KNERI----------RILPNLRVLARSSPEDKRLLVET 828
Query 170 LK 171
LK
Sbjct 829 LK 830
> ath:AT4G37640 ACA2; ACA2 (CALCIUM ATPASE 2); calcium ion transmembrane
transporter/ calcium-transporting ATPase/ calmodulin
binding; K01537 Ca2+-transporting ATPase [EC:3.6.3.8]
Length=1014
Score = 82.8 bits (203), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 56/171 (32%), Positives = 80/171 (46%), Gaps = 49/171 (28%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RT+C+AY + + P+ P F C+GI GI+DPVR V +VE C
Sbjct 622 RTLCLAYMDIEGGFSPD----DAIPASGF-------TCVGIVGIKDPVRPGVKESVELCR 670
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TAKAIA++C I ++ +A+ GP F +
Sbjct 671 RAGITVRMVTGDNINTAKAIARECGILTDD--GIAIEGPVFRE----------------- 711
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALK 171
N + + ++QV+ARS P DK+ LV L+
Sbjct 712 -------------------KNQEELLELIPKIQVMARSSPMDKHTLVKQLR 743
> ath:AT2G22950 calcium-transporting ATPase, plasma membrane-type,
putative / Ca2+-ATPase, putative (ACA7); K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1015
Score = 82.0 bits (201), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 55/171 (32%), Positives = 82/171 (47%), Gaps = 49/171 (28%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RT+C+AY + + + + P++ F C+GI GI+DPVR V +VE C
Sbjct 623 RTLCLAYMDIE----SGFSADEGIPEKGF-------TCIGIVGIKDPVRPGVRESVELCR 671
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
+AGI VRMVTGDN+ TAKAIA++C I ++ +A+ GP F +
Sbjct 672 RAGIMVRMVTGDNINTAKAIARECGILTDD--GIAIEGPVFRE----------------- 712
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALK 171
N + + ++QV+ARS P DK+ LV L+
Sbjct 713 -------------------KNQEEMLELIPKIQVMARSSPMDKHTLVKQLR 744
> ath:AT4G29900 ACA10; ACA10 (AUTOINHIBITED CA(2+)-ATPASE 10);
calcium-transporting ATPase/ calmodulin binding; K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1069
Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 59/175 (33%), Positives = 86/175 (49%), Gaps = 43/175 (24%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + IA+R F+ ++P +E+ + + E DLI L I GI+DP R V +V C
Sbjct 645 RCVAIAFRTFEADKIPTDEEQL----SRWELPEDDLILLAIVGIKDPCRPGVKNSVLLCQ 700
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
QAG+ VRMVTGDN+ TAKAIA +C I
Sbjct 701 QAGVKVRMVTGDNIQTAKAIALECGIL--------------------------------- 727
Query 121 ATDAKTAEA---EGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALKQ 172
A+D+ +E EGK R + + +RI + + V+ RS P+DK +LV +LK+
Sbjct 728 ASDSDASEPNLIEGKVFRSY---SEEERDRICEEISVMGRSSPNDKLLLVQSLKR 779
> ath:AT2G41560 ACA4; ACA4 (AUTO-INHIBITED CA(2+)-ATPASE, ISOFORM
4); calcium-transporting ATPase/ calmodulin binding; K01537
Ca2+-transporting ATPase [EC:3.6.3.8]
Length=1030
Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 57/172 (33%), Positives = 81/172 (47%), Gaps = 51/172 (29%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RT+C+ Y++ D E P+ + + + + + GI+DPVR V AV+ C
Sbjct 619 RTLCLVYKDLD--EAPSGE-----------LPDGGYTMVAVVGIKDPVRPGVREAVQTCQ 665
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
AGI VRMVTGDN+ TAKAIAK+C I+ E G LA+ G EF L
Sbjct 666 AAGITVRMVTGDNISTAKAIAKECGIYTE--GGLAIEGSEFRDL---------------- 707
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQVLARSQPSDKYVLVTALKQ 172
+ I ++QV+ARS P DK+ LV+ L++
Sbjct 708 --------------------SPHEMRAIIPKIQVMARSLPLDKHTLVSNLRK 739
> ath:AT5G57110 ACA8; ACA8 (AUTOINHIBITED CA2+ -ATPASE, ISOFORM
8); calcium-transporting ATPase/ calmodulin binding / protein
self-association
Length=1074
Score = 78.6 bits (192), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 57/177 (32%), Positives = 85/177 (48%), Gaps = 48/177 (27%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + +A+R ++ +VP +E +++ E DLI L I GI+DP R V +V C
Sbjct 642 RCVALAFRTYEAEKVPTGEELS-----KWVLPEDDLILLAIVGIKDPCRPGVKDSVVLCQ 696
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
AG+ VRMVTGDN+ TA+AIA +C I
Sbjct 697 NAGVKVRMVTGDNVQTARAIALECGIL--------------------------------- 723
Query 121 ATDAKTAEA---EGKNLRVDVIGNMDAFER--IWKRLQVLARSQPSDKYVLVTALKQ 172
++DA +E EGK+ R M ER I ++ V+ RS P+DK +LV +L++
Sbjct 724 SSDADLSEPTLIEGKSFR-----EMTDAERDKISDKISVMGRSSPNDKLLLVQSLRR 775
> ath:AT3G22910 calcium-transporting ATPase, plasma membrane-type,
putative / Ca(2+)-ATPase, putative (ACA13); K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1017
Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 54/146 (36%), Positives = 73/146 (50%), Gaps = 41/146 (28%)
Query 31 VAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEE 90
+ E+ L LGI GI+DP R V AVE C AG+N++M+TGDN+ TA+AIA +C I
Sbjct 629 LKEEKLSLLGIIGIKDPCRPGVKKAVEDCQFAGVNIKMITGDNIFTARAIAVECGI---- 684
Query 91 RGDLAMLGPEFTQLVGGVVCQNCRTAICGCATDAKTAEA--EGKNLRVDVIGNMDAFERI 148
L PE D +EA EG+ R N ER+
Sbjct 685 ------LTPE----------------------DEMNSEAVLEGEKFR-----NYTQEERL 711
Query 149 WK--RLQVLARSQPSDKYVLVTALKQ 172
K R++V+ARS P DK ++V LK+
Sbjct 712 EKVERIKVMARSSPFDKLLMVKCLKE 737
> ath:AT3G21180 ACA9; ACA9 (AUTOINHIBITED CA(2+)-ATPASE 9); calcium-transporting
ATPase/ calmodulin binding; K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1086
Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 41/174 (23%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + IA R ++++VP KE++ K + + E +LI L I GI+DP R V AV C
Sbjct 658 RCVAIACRTQELNQVP--KEQEDLDK--WALPEDELILLAIVGIKDPCRPGVREAVRICT 713
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
AG+ VRMVTGDNL TAKAIA +C I + + T+ V +
Sbjct 714 SAGVKVRMVTGDNLQTAKAIALECGILSSD-----------TEAVEPTII---------- 752
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFER--IWKRLQVLARSQPSDKYVLVTALKQ 172
EGK R + ER + K++ V+ RS P+DK +LV AL++
Sbjct 753 ---------EGKVFR-----ELSEKEREQVAKKITVMGRSSPNDKLLLVQALRK 792
> ath:AT3G57330 ACA11; ACA11 (autoinhibited Ca2+-ATPase 11); calcium-transporting
ATPase/ calmodulin binding; K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1025
Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 58/174 (33%), Positives = 78/174 (44%), Gaps = 55/174 (31%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RT+C+ Y + D E P + P + + + + GI+DPVR V AV+ C
Sbjct 616 RTLCLVYTDLD--EAP----RGDLPNGGYTL-------VAVVGIKDPVRPGVREAVQTCQ 662
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGDLAMLGPEFTQLVGGVVCQNCRTAICGC 120
AGI VRMVTGDN+ TAKAIAK+C I GGV
Sbjct 663 AAGITVRMVTGDNISTAKAIAKECGILT----------------AGGVAI---------- 696
Query 121 ATDAKTAEAEGKNLRVDVIGNMDAFER--IWKRLQVLARSQPSDKYVLVTALKQ 172
EG + R N+ E I ++QV+ARS P DK+ LV L++
Sbjct 697 ---------EGSDFR-----NLPPHEMRAILPKIQVMARSLPLDKHTLVNNLRK 736
> pfa:PFA_0310c calcium-transporting ATPase, putative (EC:3.6.3.8);
K01537 Ca2+-transporting ATPase [EC:3.6.3.8]
Length=1228
Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats.
Identities = 41/93 (44%), Positives = 55/93 (59%), Gaps = 6/93 (6%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
RT+ AY++ ++ N K + EQDLI LG GI DP R+ V A+ CH
Sbjct 759 RTLSFAYKKLSSKDL-NIKNTD-----DYYKLEQDLIYLGGLGIIDPPRKYVGRAIRLCH 812
Query 61 QAGINVRMVTGDNLITAKAIAKKCHIFNEERGD 93
AGI V M+TGDN+ TA+AIAK+ +I N+ GD
Sbjct 813 MAGIRVFMITGDNINTARAIAKEINILNKNEGD 845
> hsa:487 ATP2A1, ATP2A, SERCA1; ATPase, Ca++ transporting, cardiac
muscle, fast twitch 1 (EC:3.6.3.8); K05853 Ca2+ transporting
ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=994
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 42/92 (45%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
FL E DL +G+ G+ DP R+EV G+++ C AGI V M+TGDN TA AI ++ IF
Sbjct 584 FLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFG 643
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
NEE D A G EF L + CR A C
Sbjct 644 ENEEVADRAYTGREFDDLPLAEQREACRRACC 675
> sce:YDR039C ENA2; Ena2p (EC:3.6.3.7 3.6.3.12); K01536 Na+-exporting
ATPase [EC:3.6.3.7]
Length=1091
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 60/112 (53%), Gaps = 10/112 (8%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + A + F +V + + K ++ AE DL+ LG+ GI DP R E GAV++ H
Sbjct 606 RVLGFASKSFTKDQVNDDQLKNITSNRA--TAESDLVFLGLIGIYDPPRNETAGAVKKFH 663
Query 61 QAGINVRMVTGDNLITAKAIAKKC--------HIFNEERGDLAMLGPEFTQL 104
QAGINV M+TGD + TAKAIA++ H E + M G +F L
Sbjct 664 QAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGL 715
> sce:YDR038C ENA5; Ena5p (EC:3.6.3.7)
Length=1091
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 60/112 (53%), Gaps = 10/112 (8%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + A + F +V + + K ++ AE DL+ LG+ GI DP R E GAV++ H
Sbjct 606 RVLGFASKSFTKDQVNDDQLKNITSNRA--TAESDLVFLGLIGIYDPPRNETAGAVKKFH 663
Query 61 QAGINVRMVTGDNLITAKAIAKKC--------HIFNEERGDLAMLGPEFTQL 104
QAGINV M+TGD + TAKAIA++ H E + M G +F L
Sbjct 664 QAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGL 715
> sce:YDR040C ENA1, HOR6, PMR2; Ena1p (EC:3.6.3.7)
Length=1091
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 60/112 (53%), Gaps = 10/112 (8%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCH 60
R + A + F +V + + K ++ AE DL+ LG+ GI DP R E GAV++ H
Sbjct 606 RVLGFASKSFTKDQVNDDQLKNITSNRA--TAESDLVFLGLIGIYDPPRNETAGAVKKFH 663
Query 61 QAGINVRMVTGDNLITAKAIAKKC--------HIFNEERGDLAMLGPEFTQL 104
QAGINV M+TGD + TAKAIA++ H E + M G +F L
Sbjct 664 QAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGL 715
> mmu:11937 Atp2a1, SERCA1; ATPase, Ca++ transporting, cardiac
muscle, fast twitch 1 (EC:3.6.3.8); K05853 Ca2+ transporting
ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=994
Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 41/92 (44%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
F+ E DL +G+ G+ DP R+EV G+++ C AGI V M+TGDN TA AI ++ IF
Sbjct 584 FMEYEMDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFS 643
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
NEE D A G EF L + CR A C
Sbjct 644 ENEEVTDRAYTGREFDDLPLAEQREACRRACC 675
> ath:AT3G63380 calcium-transporting ATPase, plasma membrane-type,
putative / Ca(2+)-ATPase, putative (ACA12); K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1033
Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 51/142 (35%), Positives = 73/142 (51%), Gaps = 34/142 (23%)
Query 31 VAEQD-LICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNE 89
V E+D L +GI G++DP R V AVE C AG+ ++M+TGDN+ TAKAIA +C I +
Sbjct 632 VLEEDGLTLMGIVGLKDPCRPGVSKAVETCKLAGVTIKMITGDNVFTAKAIAFECGILDH 691
Query 90 ERGDLAMLGPEFTQLVGGVVCQNCRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIW 149
D E +V GV +N TD E + +VD
Sbjct 692 NDKD------EEDAVVEGVQFRNY--------TD------EERMQKVD------------ 719
Query 150 KRLQVLARSQPSDKYVLVTALK 171
+++V+ARS PSDK ++V L+
Sbjct 720 -KIRVMARSSPSDKLLMVKCLR 740
> tgo:TGME49_030420 calcium-transporting ATPase, putative (EC:3.6.3.8);
K01537 Ca2+-transporting ATPase [EC:3.6.3.8]
Length=1093
Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 41/116 (35%), Positives = 62/116 (53%), Gaps = 13/116 (11%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQ-----------SFLVAEQDLICLGIFGIQDPVR 49
RT+ +A + D E+ ++ P+ + +F E DLI LG+ G+ DP R
Sbjct 611 RTLALAMKR-DCGELADYDSASPSESRHPARKLLEDAANFAKIESDLIFLGLVGLMDPPR 669
Query 50 EEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEE-RGDLAMLGPEFTQL 104
EV A++ C AGI V M+TGDN +TA+A+A HI ++ G+ + G EF L
Sbjct 670 PEVSAAIDACRGAGIKVVMITGDNKLTAEAVASMIHIVDDGCVGNCSFTGKEFEGL 725
> xla:495440 atp2a3, serca3; ATPase, Ca++ transporting, ubiquitous
(EC:3.6.3.8); K05853 Ca2+ transporting ATPase, sarcoplasmic/endoplasmic
reticulum [EC:3.6.3.8]
Length=1033
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 45/117 (38%), Positives = 62/117 (52%), Gaps = 4/117 (3%)
Query 4 CIAYREFDVSEVPNWKEKQPAPKQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAG 63
C+A DV P ++ Q F+ E +L +G G+ DP R+EV ++E C +AG
Sbjct 561 CLALATRDVP--PKLEDLQLEDSTKFINYETNLTFVGCVGMLDPPRKEVSTSIELCKKAG 618
Query 64 INVRMVTGDNLITAKAIAKKCHIFN--EERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
I V M+TGDN TA AI +K IF+ E+ D A G EF L + CR+A C
Sbjct 619 IKVIMITGDNKGTAVAICRKIGIFSEYEDITDKAYTGREFDDLSPEKQREACRSARC 675
> hsa:489 ATP2A3, SERCA3; ATPase, Ca++ transporting, ubiquitous
(EC:3.6.3.8); K05853 Ca2+ transporting ATPase, sarcoplasmic/endoplasmic
reticulum [EC:3.6.3.8]
Length=999
Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 41/92 (44%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
F+ E DL +G G+ DP R EV + RC+QAGI V M+TGDN TA AI ++ IF
Sbjct 584 FVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFG 643
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
E+ A G EF L Q CRTA C
Sbjct 644 DTEDVAGKAYTGREFDDLSPEQQRQACRTARC 675
> ath:AT4G00900 ECA2; ECA2 (ER-TYPE CA2+-ATPASE 2); calcium-transporting
ATPase; K01537 Ca2+-transporting ATPase [EC:3.6.3.8]
Length=1054
Score = 66.2 bits (160), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 9/112 (8%)
Query 1 RTICIAYREFDVSEVPNWK-EKQPAPKQ-----SFLVAEQDLICLGIFGIQDPVREEVPG 54
R + +AY++ ++ E ++ E+ P+ K+ S+ E +LI +G+ G++DP REEV
Sbjct 573 RCLGLAYKD-ELGEFSDYSSEEHPSHKKLLDPSSYSNIETNLIFVGVVGLRDPPREEVGR 631
Query 55 AVERCHQAGINVRMVTGDNLITAKAIAKKCHIF--NEERGDLAMLGPEFTQL 104
A+E C AGI V ++TGDN TA+AI + +F NE+ + G EF L
Sbjct 632 AIEDCRDAGIRVMVITGDNKSTAEAICCEIRLFSENEDLSQSSFTGKEFMSL 683
> cel:K11D9.2 sca-1; SERCA (Sarco-Endoplasmic Reticulum Calcium
ATPase) family member (sca-1); K05853 Ca2+ transporting ATPase,
sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=1004
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 36/90 (40%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
F+ EQD+ +G+ G+ DP R EV +++ C+ AGI V M+TGDN TA+AI ++ +F
Sbjct 585 FVKYEQDITFVGVVGMLDPPRTEVSDSIKACNHAGIRVIMITGDNKNTAEAIGRRIGLFG 644
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTA 116
NE+ A G EF L + CR A
Sbjct 645 ENEDTTGKAYTGREFDDLPPEQQSEACRRA 674
> xla:380096 atp2a2, MGC52615, atp2b, ca-p60a, dar, serca2; ATPase,
Ca++ transporting, cardiac muscle, slow twitch 2; K05853
Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum
[EC:3.6.3.8]
Length=996
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
F+ E DL +G G+ DP R+EV G+++ C +AGI V M+TGDN TA AI ++ IF
Sbjct 584 FVDYETDLTFVGCVGMLDPPRKEVMGSIKLCREAGIRVIMITGDNKGTAIAICRRIGIFG 643
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
N++ LA G EF L + C+ A C
Sbjct 644 ENDDVSRLAFTGREFDDLPPAEQREACKRASC 675
> mmu:53313 Atp2a3, SERCA3b, Serca3; ATPase, Ca++ transporting,
ubiquitous (EC:3.6.3.8); K05853 Ca2+ transporting ATPase,
sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=999
Score = 63.5 bits (153), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 40/92 (43%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFN 88
F+ E DL +G G+ DP R EV + RC +AGI V M+TGDN TA AI ++ IF
Sbjct 584 FVQYETDLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFG 643
Query 89 EERGDL--AMLGPEFTQLVGGVVCQNCRTAIC 118
+ L A G EF L Q CRTA C
Sbjct 644 DTEDVLGKAYTGREFDDLSPEQQRQACRTARC 675
> xla:446229 atp2a1, atp2a, atp2a2, serca1; ATPase, Ca++ transporting,
cardiac muscle, fast twitch 1 (EC:3.6.3.8); K05853
Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum
[EC:3.6.3.8]
Length=1042
Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Query 26 KQSFLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCH 85
+F+ E +L +G G+ DP R EV +V+ C QAGI V M+TGDN TA AI ++
Sbjct 580 SNNFINYETNLTFVGCVGMLDPPRTEVAASVKMCRQAGIRVIMITGDNKGTAVAICRRVG 639
Query 86 IFNEERG--DLAMLGPEFTQLVGGVVCQNCRTAIC 118
IF E+ D A G EF +L C A C
Sbjct 640 IFREDDDVTDKAFTGREFDELSPAAQRDACLNARC 674
> tpv:TP02_0524 calcium-transporting ATPase; K01537 Ca2+-transporting
ATPase [EC:3.6.3.8]
Length=1277
Score = 62.0 bits (149), Expect = 9e-10, Method: Composition-based stats.
Identities = 28/54 (51%), Positives = 39/54 (72%), Gaps = 0/54 (0%)
Query 33 EQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHI 86
E+D+ LG+ GI DP R EV ++ +C +AGI V M+TGDN +TA+AIA+K I
Sbjct 740 EKDMTFLGLVGIMDPPRPEVKDSISKCMRAGIRVIMITGDNKLTAEAIARKVGI 793
> dre:568265 atp2a2b, SERCA2, fb51e04, fb80c02, si:dkey-83d9.6,
wu:fb51e04, wu:fb80c02, zK83D9.6; ATPase, Ca++ transporting,
cardiac muscle, slow twitch 2b; K05853 Ca2+ transporting
ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=1035
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF- 87
F+ E DL +G G+ DP R EV +++ C QAGI V M+TGDN TA AI ++ IF
Sbjct 576 FVEYETDLTFVGCVGMLDPPRAEVAASIKLCRQAGIRVIMITGDNKGTAVAICRRIGIFG 635
Query 88 -NEERGDLAMLGPEFTQLVGGVVCQNCRTAIC 118
N++ +A G EF L + TA C
Sbjct 636 ENDDVSRMAYTGREFDDLSAAAQREAVLTARC 667
> ath:AT1G59820 ALA3; ALA3 (Aminophospholipid ATPase3); ATPase,
coupled to transmembrane movement of ions, phosphorylative
mechanism / phospholipid transporter; K14802 phospholipid-transporting
ATPase [EC:3.6.3.1]
Length=1213
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 11/101 (10%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFL-----------VAEQDLICLGIFGIQDPVR 49
RT+C+AY++ + +W EK K + + E+DLI +G I+D ++
Sbjct 628 RTLCLAYKDLNPETYDSWNEKFIQAKSALRDREKKLDEVAELIEKDLILIGSTAIEDKLQ 687
Query 50 EEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEE 90
E VP +E +AGI + ++TGD + TA IA C++ N E
Sbjct 688 EGVPTCIETLSRAGIKIWVLTGDKMETAINIAYACNLINNE 728
> ath:AT5G44240 haloacid dehalogenase-like hydrolase family protein;
K01530 phospholipid-translocating ATPase [EC:3.6.3.1]
Length=1107
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPKQSFLV------------AEQDLICLGIFGIQDPV 48
RT+C+A+RE + +E W K S LV E DL LG+ I+D +
Sbjct 556 RTLCLAWRELEENEYLEWSVKF-KEASSLLVDREWRIAEVCQRLEHDLYILGVTAIEDRL 614
Query 49 REEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFN-EERGDLAML 97
++ VP +E +AGIN M+TGD TA IA C+ + E +G L M+
Sbjct 615 QDGVPETIETLRKAGINFWMLTGDKQNTAIQIALSCNFISPEPKGQLLMI 664
> cpv:cgd7_4190 cation-transporting P-type ATpase with 11 or more
transmembrane domains ; K01537 Ca2+-transporting ATPase
[EC:3.6.3.8]
Length=1129
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/105 (36%), Positives = 58/105 (55%), Gaps = 11/105 (10%)
Query 1 RTICIAYREFDVSEVPNWKEKQPAPK--------QSFLVAEQDLICLGIFGIQDPVREEV 52
RT+ A + ++ E+ + QP K +F+ E+DL +G+ GI DP R V
Sbjct 588 RTLACAVKVDNLGELSTYN-GQPKSKGAALLSDPSNFVNIEKDLCFIGVMGIYDPPRPGV 646
Query 53 PGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIF--NEERGDLA 95
A++RC +AGI V M+TGDN TA+AIA I ++E D++
Sbjct 647 KNAIQRCQKAGIRVFMITGDNRNTAEAIASSIGILRGSKEEWDIS 691
> dre:494489 atp2a1l, zgc:154094; ATPase, Ca++ transporting, cardiac
muscle, fast twitch 1 like; K05853 Ca2+ transporting
ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
Length=991
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 38/92 (41%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query 29 FLVAEQDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFN 88
F E DL +G G+ DP R+EV G++E C AGI V M+TGDN TA AI ++ IF+
Sbjct 581 FADYETDLTFVGCVGMLDPPRKEVTGSIELCRAAGIRVIMITGDNKGTAVAICRRIGIFS 640
Query 89 EERG--DLAMLGPEFTQLVGGVVCQNCRTAIC 118
E+ A G EF L + R A C
Sbjct 641 EDEDVTGKAYTGREFDDLPHSEQSEAVRRACC 672
> dre:64613 atp1a1a.2, atp1a1l2, atp[a]1A2b, cb703, zgc:110523;
ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide
Length=1023
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 47/134 (35%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query 34 QDLICLGIFGIQDPVREEVPGAVERCHQAGINVRMVTGDNLITAKAIAKKCHIFNEERGD 93
++L LG+ + DP R VP AV +C AGI V MVTGD+ ITAKAIAK I +E
Sbjct 581 ENLCFLGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNET 640
Query 94 LAMLGPEFTQLVGGVVCQNCRTAICGCATDAKTAEAEGKNLRVDVIGNMDAFERIWKRLQ 153
+ + VG V N R +AK G L+ ++D R +
Sbjct 641 VEDIAARMNIPVGEV---NPR--------EAKACVVHGGELKNMNDSDLDEILRYHTEI- 688
Query 154 VLARSQPSDKYVLV 167
V AR+ P K ++V
Sbjct 689 VFARTSPQQKLIIV 702
Lambda K H
0.322 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4341553636
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40