bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0527_orf2
Length=378
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_065330 protein kinase 3 (EC:2.7.11.26); K03083 glyc... 508 2e-143
bbo:BBOV_III003600 17.m07339; protein kinase domain containing... 391 3e-108
pfa:PFC0525c PfGSK-3, PfGSK3; glycogen synthase kinase 3; K030... 389 1e-107
cpv:cgd4_240 hypothetical protein 382 1e-105
tpv:TP03_0047 glycogen synthase kinase (EC:2.7.1.37); K08286 p... 365 2e-100
ath:AT4G00720 ATSK32; ATSK32 (SHAGGY-LIKE PROTEIN KINASE 32); ... 362 1e-99
hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.26)... 359 1e-98
mmu:56637 Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, ... 359 1e-98
dre:560194 MGC158379, zgc:158379; si:ch211-39e15.2 (EC:2.7.11.... 358 1e-98
dre:30664 gsk3a, GSK-3[a], GSK-3[b], GSK3; glycogen synthase k... 358 2e-98
dre:557882 novel protein similar to glycogen synthase kinase 3... 358 2e-98
mmu:606496 Gsk3a, 2700086H06Rik; glycogen synthase kinase 3 al... 357 3e-98
xla:399097 gsk3b, MGC131076, gsk-3, gsk3, gsk3-beta, gsk3beta,... 357 6e-98
hsa:2931 GSK3A, DKFZp686D0638; glycogen synthase kinase 3 alph... 356 1e-97
dre:30654 gsk3b, GSK-3[b], GSK3, fk80d11, wu:fb68h05, wu:fk80d... 355 1e-97
ath:AT5G14640 SK13; SK13 (SHAGGY-LIKE KINASE 13); ATP binding ... 355 1e-97
ath:AT3G61160 shaggy-related protein kinase beta / ASK-beta (A... 354 3e-97
ath:AT1G09840 ATSK41; ATSK41 (SHAGGY-LIKE PROTEIN KINASE 41); ... 350 7e-96
ath:AT3G05840 ATSK12; ATSK12; protein kinase/ protein serine/t... 348 2e-95
ath:AT2G30980 ASKdZeta (Arabidopsis SHAGGY-related protein kin... 348 2e-95
ath:AT1G06390 GSK1; GSK1 (GSK3/SHAGGY-LIKE PROTEIN KINASE 1); ... 348 2e-95
ath:AT1G57870 ATSK42; ATSK42 (ARABIDOPSIS SHAGGY-LIKE KINASE 4... 346 7e-95
ath:AT5G26751 ATSK11; ATSK11; protein kinase/ protein serine/t... 346 8e-95
cel:Y18D10A.5 gsk-3; Glycogen Synthase Kinase family member (g... 343 6e-94
ath:AT4G18710 BIN2; BIN2 (BRASSINOSTEROID-INSENSITIVE 2); glyc... 343 8e-94
sce:YMR139W RIM11, GSK3, MDS1; Protein kinase required for sig... 303 9e-82
sce:YDL079C MRK1; Glycogen synthase kinase 3 (GSK-3) homolog; ... 302 1e-81
cel:C44H4.6 hypothetical protein; K03083 glycogen synthase kin... 232 2e-60
sce:YNL307C MCK1, CMS1, YPK1; Mck1p (EC:2.7.12.1); K00924 [EC... 231 4e-60
sce:YOL128C YGK3; Protein kinase related to mammalian glycogen... 196 2e-49
hsa:1017 CDK2, p33(CDK2); cyclin-dependent kinase 2 (EC:2.7.11... 184 4e-46
ath:AT3G48750 CDC2; CDC2 (CELL DIVISION CONTROL 2); cyclin-dep... 184 6e-46
mmu:12566 Cdk2, A630093N05Rik; cyclin-dependent kinase 2 (EC:2... 183 1e-45
hsa:1018 CDK3; cyclin-dependent kinase 3 (EC:2.7.11.22); K0208... 182 1e-45
pfa:PF14_0294 PfMAP1; mitogen-activated protein kinase 1; K043... 182 2e-45
xla:399314 cdk2, eg1; cyclin-dependent kinase 2 (EC:2.7.11.22)... 182 2e-45
dre:406715 cdk2, wu:fa10c02, zgc:56598, zgc:77684; cyclin-depe... 181 4e-45
mmu:23939 Mapk7, BMK1, ERK5, Erk5-T, PRKM7; mitogen-activated ... 179 1e-44
hsa:5598 MAPK7, BMK1, ERK4, ERK5, PRKM7; mitogen-activated pro... 179 2e-44
xla:432036 hypothetical protein MGC81499; K02206 cyclin-depend... 179 2e-44
ath:AT1G66750 CAK4; CAK4 (CDK-ACTIVATING KINASE 4); kinase/ pr... 176 2e-43
tgo:TGME49_085160 cyclin-dependent kinase-like 5, putative (EC... 174 5e-43
mmu:53886 Cdkl2, 5330436L21Rik, AI505225, KKIAMRE, Kkm, MGC144... 171 3e-42
ath:AT1G76540 CDKB2;1 (cyclin-dependent kinase B2;1); cyclin-d... 171 4e-42
ath:AT1G73690 CDKD1;1 (CYCLIN-DEPENDENT KINASE D1;1); ATP bind... 170 9e-42
tpv:TP01_0678 serine/threonine protein kinase 170 1e-41
cpv:cgd5_2510 Cdc2-like CDK2/CDC28 like protein kinase ; K0456... 169 1e-41
hsa:5595 MAPK3, ERK1, HS44KDAP, HUMKER1A, MGC20180, P44ERK1, P... 169 1e-41
dre:360144 mapk1, zERK2; mitogen-activated protein kinase 1 (E... 169 1e-41
hsa:8999 CDKL2, KKIAMRE, P56; cyclin-dependent kinase-like 2 (... 169 2e-41
> tgo:TGME49_065330 protein kinase 3 (EC:2.7.11.26); K03083 glycogen
synthase kinase 3 beta [EC:2.7.11.26]
Length=394
Score = 508 bits (1308), Expect = 2e-143, Method: Compositional matrix adjust.
Identities = 242/318 (76%), Positives = 283/318 (88%), Gaps = 6/318 (1%)
Query 5 SSSSKGNRRS--ASGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRY 62
+++ KG R+S +G P +YD+G+VLGNGSFGVVTEARC++TGE VAIKKVLQDPRY
Sbjct 25 TTAVKGERQSRVHTGNPHPTLTYDIGRVLGNGSFGVVTEARCVDTGEVVAIKKVLQDPRY 84
Query 63 KNRELEIMKALEHPNIVRLLDYFYTEVEERGSI--SRFLNVVMEFVPETVYRVMKSFIKS 120
KNREL+IMK L+HPN+V+L+DYFYTE+ ER S +RFLNVVME +PETVYRVMKSF+++
Sbjct 85 KNRELDIMKELKHPNVVKLIDYFYTEMGERDSNDHNRFLNVVMEHIPETVYRVMKSFLRA 144
Query 121 STHALPFILIKLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLV 180
+ +PFILIKLYTYQMCR+LGYLHALGICHRD+KPQNLLVD RTHVLKLCDFGSAKRLV
Sbjct 145 N-QQVPFILIKLYTYQMCRALGYLHALGICHRDIKPQNLLVDSRTHVLKLCDFGSAKRLV 203
Query 181 PGEQSVAYICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVK 240
PGEQSV+YICSRFYRAPELMLGA+EYTTAID+WS+GCVLGELLLGRPLFAGETSVDQLVK
Sbjct 204 PGEQSVSYICSRFYRAPELMLGASEYTTAIDVWSIGCVLGELLLGRPLFAGETSVDQLVK 263
Query 241 IIQILGTPTRCQMSAMNPNYLEFRFPDVKPKDWKAVFASHDCAL-GGDKSFEQAVDLMSK 299
IIQILGTP+R QMS MNPNY EFRFPDVKP++WK++FASH + D S++QA+DL++K
Sbjct 264 IIQILGTPSRRQMSTMNPNYTEFRFPDVKPREWKSIFASHIASTETNDPSWDQALDLLTK 323
Query 300 LLRYEPEQRLQPLEALAH 317
LRYEP +RL PLEALAH
Sbjct 324 FLRYEPGERLLPLEALAH 341
> bbo:BBOV_III003600 17.m07339; protein kinase domain containing
protein
Length=473
Score = 391 bits (1004), Expect = 3e-108, Method: Compositional matrix adjust.
Identities = 181/303 (59%), Positives = 233/303 (76%), Gaps = 9/303 (2%)
Query 15 ASGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALE 74
A + + + Y + +++GNGSFGVV EA +E+G +VAIKKVLQDPRYKNREL IM L
Sbjct 136 ADTLPEAESKYQVQRMIGNGSFGVVHEAIHVESGNKVAIKKVLQDPRYKNRELSIMLELS 195
Query 75 HPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYT 134
HPNIV + D+FYTEV +LN+VMEFVP TV+R+M+S+ K +P LIK+Y
Sbjct 196 HPNIVYMFDHFYTEVVREQETQIYLNIVMEFVPGTVHRMMRSYFKRYNQ-MPIALIKVYA 254
Query 135 YQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFY 194
+Q+C++LGYLHA+G+CHRD+KP NLLVD T+VLKLCDFGSAK+L GE SVAYICSRFY
Sbjct 255 FQLCKALGYLHAVGVCHRDLKPHNLLVDLETNVLKLCDFGSAKKLRAGEMSVAYICSRFY 314
Query 195 RAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMS 254
RAPELMLGA EYTTAIDIWS+GCV+GELL+G+P+FAG+TS+DQLVKIIQ+LGTPT QM
Sbjct 315 RAPELMLGATEYTTAIDIWSIGCVIGELLMGKPMFAGDTSIDQLVKIIQVLGTPTIEQMY 374
Query 255 AMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEA 314
AM+PNY FP+++ D +F ++ + A+D +S+ LRY+P++RL+PLEA
Sbjct 375 AMHPNYQNVTFPNIRAADLTRLFPTNTPPV--------AIDFVSQFLRYDPKERLRPLEA 426
Query 315 LAH 317
L H
Sbjct 427 LGH 429
> pfa:PFC0525c PfGSK-3, PfGSK3; glycogen synthase kinase 3; K03083
glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=440
Score = 389 bits (998), Expect = 1e-107, Method: Compositional matrix adjust.
Identities = 175/298 (58%), Positives = 236/298 (79%), Gaps = 9/298 (3%)
Query 19 QQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNI 78
+ P KSY +G ++GNGSFGVV EA C++T E+VAIKKVLQDP+YKNREL IMK L H NI
Sbjct 61 RSPNKSYKLGNIIGNGSFGVVYEAICIDTSEQVAIKKVLQDPQYKNRELMIMKNLNHINI 120
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
+ L DY+YTE ++ + FLNVVME++P+TV++ MK + +++ ALP L+KLY+YQ+C
Sbjct 121 IYLKDYYYTESFKKNEKNIFLNVVMEYIPQTVHKYMKYYSRNN-QALPMFLVKLYSYQLC 179
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPE 198
R+L Y+H+ ICHRD+KPQNLL+D RTH LKLCDFGSAK L+ G++SV+YICSRFYRAPE
Sbjct 180 RALSYIHSKFICHRDLKPQNLLIDPRTHTLKLCDFGSAKNLLAGQRSVSYICSRFYRAPE 239
Query 199 LMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNP 258
LMLG+ YTT ID+WSLGC++ E++LG P+F+G++SVDQLV+IIQ+LGTPT Q+ MNP
Sbjct 240 LMLGSTNYTTHIDLWSLGCIIAEMILGYPIFSGQSSVDQLVRIIQVLGTPTEDQLKEMNP 299
Query 259 NYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
NY + +FPDVK KD + VF + ++A++L+++ L+YEP +RL P+EALA
Sbjct 300 NYADIKFPDVKSKDLRKVFPK--------GTPDEAINLITQFLKYEPLKRLNPIEALA 349
> cpv:cgd4_240 hypothetical protein
Length=433
Score = 382 bits (981), Expect = 1e-105, Method: Compositional matrix adjust.
Identities = 181/347 (52%), Positives = 247/347 (71%), Gaps = 41/347 (11%)
Query 1 TFSSSSSSKGNRRSASGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDP 60
T SS S+ S++ ++ K Y +G+ LG GSFG+V E +E+G+R A+KKVLQDP
Sbjct 37 TLSSGLSTTAT--SSTNLETSSKKYSLGKTLGTGSFGIVCEVFDIESGKRFALKKVLQDP 94
Query 61 RYKNRELEIMKALEHPNIVRLLDYFYTEVEE----------------------------- 91
RYKNREL+IMK L+H NI++L+DYFYT +E
Sbjct 95 RYKNRELDIMKVLDHVNIIKLVDYFYTTGDEEPKPPQPPDDHNKLGGKNNGVNNHHKSVI 154
Query 92 -RGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYLHALGIC 150
S +++LNV+ME+VP+T+++V+KSFI+S ++P LI +Y YQ+ R++G++H+LGIC
Sbjct 155 VNPSQNKYLNVIMEYVPDTLHKVLKSFIRSG-RSIPMNLISIYIYQLFRAVGFIHSLGIC 213
Query 151 HRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLGANEYTTAI 210
HRD+KPQNLLV+ + + LKLCDFGSAK+L+P E SVAYICSRFYRAPELMLGA EYT +I
Sbjct 214 HRDIKPQNLLVNSKDNTLKLCDFGSAKKLIPSEPSVAYICSRFYRAPELMLGATEYTPSI 273
Query 211 DIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLEFRFPDVKP 270
D+WS+GCV GEL+LG+PLF+GETS+DQLV+IIQI+GTPT+ QM MNP+Y E RFP +K
Sbjct 274 DLWSIGCVFGELILGKPLFSGETSIDQLVRIIQIMGTPTKEQMIRMNPHYTEVRFPTLKA 333
Query 271 KDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
KDW+ + +L A+DL+ ++LRYEP+ R+ P EA+AH
Sbjct 334 KDWRKILPEGTPSL--------AIDLLEQILRYEPDLRINPYEAMAH 372
> tpv:TP03_0047 glycogen synthase kinase (EC:2.7.1.37); K08286
protein-serine/threonine kinase [EC:2.7.11.-]
Length=408
Score = 365 bits (936), Expect = 2e-100, Method: Compositional matrix adjust.
Identities = 174/312 (55%), Positives = 231/312 (74%), Gaps = 28/312 (8%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLDY 84
Y + +V+GNGSFG+V EA L+T E+VAIKKVLQDPRYKNREL IMK L HPNI++L DY
Sbjct 15 YRLNKVIGNGSFGIVHEAYLLKTNEQVAIKKVLQDPRYKNRELTIMKDLRHPNIIKLRDY 74
Query 85 FYTEVEERGSIS------------------RFLNVVMEFVPETVYRVMKSFIKSSTHALP 126
++T V+ S S ++LN+VME++P+TV++VM+++ KS +P
Sbjct 75 YFT-VQYNNSTSTTTPSNNQAKPTKPNGEEKYLNLVMEYMPDTVHKVMRTYFKS-LGFVP 132
Query 127 FILIKLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSV 186
LI+ Y +Q+CR+ GYLH++ ICHRD+KP NLLVD T+VLKLCDFGSAK+L+ G+ SV
Sbjct 133 LNLIRTYAFQICRAFGYLHSMNICHRDLKPHNLLVDPFTNVLKLCDFGSAKKLIKGDWSV 192
Query 187 AYICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILG 246
+YICSRFYRAPELMLG+NEYTTAID WS+GCVL ELLLGRP+F G+TS+DQLVKIIQILG
Sbjct 193 SYICSRFYRAPELMLGSNEYTTAIDAWSIGCVLSELLLGRPIFCGDTSIDQLVKIIQILG 252
Query 247 TPTRCQMSAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPE 306
TP+ +M AMNP+Y FP++K + +F + + ++L+S LLRY+P
Sbjct 253 TPSVIEMKAMNPDYNNINFPNLKRVELSTIFPKN--------TDPDLINLISNLLRYDPT 304
Query 307 QRLQPLEALAHL 318
+RL+PL+AL H+
Sbjct 305 ERLKPLDALTHV 316
> ath:AT4G00720 ATSK32; ATSK32 (SHAGGY-LIKE PROTEIN KINASE 32);
ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase/ protein tyrosine kinase; K00924 [EC:2.7.1.-]
Length=472
Score = 362 bits (929), Expect = 1e-99, Method: Compositional matrix adjust.
Identities = 171/295 (57%), Positives = 223/295 (75%), Gaps = 13/295 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY +V+G GSFGVV +A+CLETGE+VAIKKVLQD RYKNREL+IM+ +HPN+VRL
Sbjct 137 SYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQIMRLQDHPNVVRLRH 196
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
F++ ++ +LN+V+E+VPETVYR K + K + H +P I ++LYTYQ+CR+L Y
Sbjct 197 SFFSTTDKD---ELYLNLVLEYVPETVYRASKHYTKMNQH-MPIIFVQLYTYQICRALNY 252
Query 144 LH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
LH +G+CHRD+KPQNLLV+ +TH LK+CDFGSAK LVPGE +++YICSR+YRAPEL+ G
Sbjct 253 LHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEPNISYICSRYYRAPELIFG 312
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A EYT AID+WS GCV+ ELLLG+PLF GE+ +DQLV+II+ILGTPTR ++ MNPNY E
Sbjct 313 ATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEIRCMNPNYTE 372
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
F+FP +K W +F + +AVDL+S+LL+Y P R LEA AH
Sbjct 373 FKFPQIKAHPWHKIFHK--------RMPPEAVDLVSRLLQYSPNLRCTALEACAH 419
> hsa:2932 GSK3B; glycogen synthase kinase 3 beta (EC:2.7.11.26);
K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=420
Score = 359 bits (922), Expect = 1e-98, Method: Compositional matrix adjust.
Identities = 185/364 (50%), Positives = 247/364 (67%), Gaps = 29/364 (7%)
Query 17 GMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEH 75
G +PQ+ SY +V+GNGSFGVV +A+ ++GE VAIKKVLQD R+KNREL+IM+ L+H
Sbjct 47 GPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDH 106
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
NIVRL +FY+ E++ + +LN+V+++VPETVYRV + + ++ LP I +KLY Y
Sbjct 107 CNIVRLRYFFYSSGEKKDEV--YLNLVLDYVPETVYRVARHYSRAK-QTLPVIYVKLYMY 163
Query 136 QMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYR 195
Q+ RSL Y+H+ GICHRD+KPQNLL+D T VLKLCDFGSAK+LV GE +V+YICSR+YR
Sbjct 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYR 223
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSA 255
APEL+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query 256 MNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PLEA
Sbjct 284 MNPNYTEFKFPQIKAHPWTKVFRP--------RTPPEAIALCSRLLEYTPTARLTPLEAC 335
Query 316 AH-----LEESEEKFRGDRRAIAFFAALIMVGVFLMFYFTTTRLEQSIKEASKLLGPTPR 370
AH L + K R A +F FTT L + A+ L+ P R
Sbjct 336 AHSFFDELRDPNVKLPNGRDTPA------------LFNFTTQELSSNPPLATILIPPHAR 383
Query 371 PEAV 374
+A
Sbjct 384 IQAA 387
> mmu:56637 Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3,
GSK-3beta, GSK3; glycogen synthase kinase 3 beta (EC:2.7.11.26);
K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=420
Score = 359 bits (921), Expect = 1e-98, Method: Compositional matrix adjust.
Identities = 185/364 (50%), Positives = 247/364 (67%), Gaps = 29/364 (7%)
Query 17 GMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEH 75
G +PQ+ SY +V+GNGSFGVV +A+ ++GE VAIKKVLQD R+KNREL+IM+ L+H
Sbjct 47 GPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDH 106
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
NIVRL +FY+ E++ + +LN+V+++VPETVYRV + + ++ LP I +KLY Y
Sbjct 107 CNIVRLRYFFYSSGEKKDEV--YLNLVLDYVPETVYRVARHYSRAK-QTLPVIYVKLYMY 163
Query 136 QMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYR 195
Q+ RSL Y+H+ GICHRD+KPQNLL+D T VLKLCDFGSAK+LV GE +V+YICSR+YR
Sbjct 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYR 223
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSA 255
APEL+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query 256 MNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PLEA
Sbjct 284 MNPNYTEFKFPQIKAHPWTKVFRP--------RTPPEAIALCSRLLEYTPTARLTPLEAC 335
Query 316 AH-----LEESEEKFRGDRRAIAFFAALIMVGVFLMFYFTTTRLEQSIKEASKLLGPTPR 370
AH L + K R A +F FTT L + A+ L+ P R
Sbjct 336 AHSFFDELRDPNVKLPNGRDTPA------------LFNFTTQELSSNPPLATILIPPHAR 383
Query 371 PEAV 374
+A
Sbjct 384 IQAA 387
> dre:560194 MGC158379, zgc:158379; si:ch211-39e15.2 (EC:2.7.11.26);
K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=462
Score = 358 bits (920), Expect = 1e-98, Method: Compositional matrix adjust.
Identities = 189/369 (51%), Positives = 246/369 (66%), Gaps = 35/369 (9%)
Query 15 ASGMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKAL 73
G +PQ+ SY +V+GNGSFGVV +AR ++T E VAIKKVLQD R+KNREL+IM+ L
Sbjct 99 GQGPDRPQEVSYTDIKVIGNGSFGVVYQARLIDTHEWVAIKKVLQDKRFKNRELQIMRKL 158
Query 74 EHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLY 133
+H NIVRL +FY E++ + +LN+V+++VPETVYRV + F K+ T +P +K+Y
Sbjct 159 DHCNIVRLRYFFYCSGEKKDEV--YLNLVLDYVPETVYRVARHFSKAKT-IIPIFYVKVY 215
Query 134 TYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRF 193
YQ+ RSL Y+H+ G+CHRD+KPQNLLVD T VLKLCDFGSAK+LV GE +V+YICSR+
Sbjct 216 MYQLFRSLAYIHSQGVCHRDIKPQNLLVDPETAVLKLCDFGSAKQLVRGEPNVSYICSRY 275
Query 194 YRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQM 253
YRAPEL+ GA +YT+ IDIWS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 276 YRAPELIFGATDYTSNIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQI 335
Query 254 SAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLE 313
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PL+
Sbjct 336 REMNPNYTEFKFPQIKAHPWTKVFKP--------RTPPEAIALCSRLLEYTPVTRLSPLQ 387
Query 314 ALAHLEESEEKFRGDRRAIAFFAALIMVGVFL--------MFYFTTTRLEQSIKEASKLL 365
A AH AFF L G L +F FTTT L + S L+
Sbjct 388 ACAH---------------AFFDELRQPGTRLPSGRELPPLFNFTTTELMIQPQLNSTLI 432
Query 366 GPTPRPEAV 374
P R + V
Sbjct 433 PPHARAQTV 441
> dre:30664 gsk3a, GSK-3[a], GSK-3[b], GSK3; glycogen synthase
kinase 3 alpha (EC:2.7.11.26); K08822 glycogen synthase kinase
3 alpha [EC:2.7.11.26]
Length=440
Score = 358 bits (920), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 175/304 (57%), Positives = 227/304 (74%), Gaps = 12/304 (3%)
Query 15 ASGMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKAL 73
G +PQ+ SY +V+GNGSFGVV +AR +++ E VAIKKVLQD R+KNREL+IM+ L
Sbjct 72 GQGPDRPQEVSYTDIKVIGNGSFGVVYQARLIDSQEMVAIKKVLQDKRFKNRELQIMRKL 131
Query 74 EHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLY 133
+H NIVRL +FY+ E++ + +LN+V++FVPETVYRV + F KS T +P I +K+Y
Sbjct 132 DHCNIVRLRYFFYSSGEKKDEV--YLNLVLDFVPETVYRVARHFNKSKT-TIPIIYVKVY 188
Query 134 TYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRF 193
YQ+ RSL Y+H+ G+CHRD+KPQNLLVD T VLKLCDFGSAK+LV GE +V+YICSR+
Sbjct 189 MYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 248
Query 194 YRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQM 253
YRAPEL+ GA +YT+ IDIWS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 249 YRAPELIFGATDYTSNIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQI 308
Query 254 SAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLE 313
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PLE
Sbjct 309 REMNPNYTEFKFPQIKAHPWTKVFKP--------RTPPEAISLCSRLLEYTPVTRLSPLE 360
Query 314 ALAH 317
A AH
Sbjct 361 ACAH 364
> dre:557882 novel protein similar to glycogen synthase kinase
3 beta (gsk3b); K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=419
Score = 358 bits (919), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 184/355 (51%), Positives = 243/355 (68%), Gaps = 29/355 (8%)
Query 17 GMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEH 75
G +PQ+ SY +V+GNGSFGVV +A+ +TGE VAIKKVLQD R+KNREL+IM+ L+H
Sbjct 47 GPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDTGELVAIKKVLQDKRFKNRELQIMRKLDH 106
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
NIVRL +FY+ +++ + +LN+VM++VPE VYRV + + K+ + LP + +KLY Y
Sbjct 107 CNIVRLRYFFYSSGDKKDEV--YLNLVMDYVPENVYRVARHYSKAKQN-LPMVYVKLYMY 163
Query 136 QMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYR 195
Q+ RSL Y+H+ GICHRD+KPQNLL+D T VLKLCDFGSAK+LV GE +V+YICSR+YR
Sbjct 164 QLFRSLAYIHSYGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLVRGEPNVSYICSRYYR 223
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSA 255
APEL+ GA +YT++IDIWS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 224 APELIFGATDYTSSIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query 256 MNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PLEA
Sbjct 284 MNPNYTEFKFPQIKAHPWTKVFRP--------RTPPEAIALCSRLLEYTPTARLTPLEAC 335
Query 316 AH-----LEESEEKFRGDRRAIAFFAALIMVGVFLMFYFTTTRLEQSIKEASKLL 365
AH L E K R ++F FTT L + AS L+
Sbjct 336 AHTFFDELREPNLKLPNGRERP------------VLFNFTTQELSNNPSLASVLI 378
> mmu:606496 Gsk3a, 2700086H06Rik; glycogen synthase kinase 3
alpha (EC:2.7.11.26); K08822 glycogen synthase kinase 3 alpha
[EC:2.7.11.26]
Length=490
Score = 357 bits (917), Expect = 3e-98, Method: Compositional matrix adjust.
Identities = 176/307 (57%), Positives = 227/307 (73%), Gaps = 14/307 (4%)
Query 15 ASGMQQPQKSYDMG----QVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIM 70
A+ Q P++S ++ +V+GNGSFGVV +AR ET E VAIKKVLQD R+KNREL+IM
Sbjct 105 ATVGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIM 164
Query 71 KALEHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILI 130
+ L+H NIVRL +FY+ E++ + +LN+V+E+VPETVYRV + F K+ P I I
Sbjct 165 RKLDHCNIVRLRYFFYSSGEKKDEL--YLNLVLEYVPETVYRVARHFTKAKL-ITPIIYI 221
Query 131 KLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYIC 190
K+Y YQ+ RSL Y+H+ G+CHRD+KPQNLLVD T VLKLCDFGSAK+LV GE +V+YIC
Sbjct 222 KVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYIC 281
Query 191 SRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTR 250
SR+YRAPEL+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR
Sbjct 282 SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTR 341
Query 251 CQMSAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQ 310
Q+ MNPNY EF+FP +K W VF S K+ +A+ L S LL Y P RL
Sbjct 342 EQIREMNPNYTEFKFPQIKAHPWTKVFKS-------SKTPPEAIALCSSLLEYTPSSRLS 394
Query 311 PLEALAH 317
PLEA AH
Sbjct 395 PLEACAH 401
> xla:399097 gsk3b, MGC131076, gsk-3, gsk3, gsk3-beta, gsk3beta,
xgsk-3; glycogen synthase kinase 3 beta (EC:2.7.11.26); K03083
glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=420
Score = 357 bits (915), Expect = 6e-98, Method: Compositional matrix adjust.
Identities = 169/299 (56%), Positives = 227/299 (75%), Gaps = 11/299 (3%)
Query 19 QQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNI 78
+Q + +Y +V+GNGSFGVV +A+ +TGE VAIKKVLQD R+KNREL+IM+ L+H NI
Sbjct 50 RQQEVTYTDTKVIGNGSFGVVYQAKLCDTGELVAIKKVLQDKRFKNRELQIMRKLDHCNI 109
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
VRL +FY+ E++ + +LN+V+++VPETVYRV + + ++ ALP I +KLY YQ+
Sbjct 110 VRLRYFFYSSGEKKDEV--YLNLVLDYVPETVYRVARHYSRAK-QALPIIYVKLYMYQLF 166
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPE 198
RSL Y+H+ GICHRD+KPQNLL+D T VLKLCDFGSAK+LV GE +V+YICSR+YRAPE
Sbjct 167 RSLAYIHSFGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPE 226
Query 199 LMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNP 258
L+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+ MNP
Sbjct 227 LIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNP 286
Query 259 NYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
NY EF+FP +K W VF + ++ +A+ L S+LL Y P RL PL+A AH
Sbjct 287 NYTEFKFPQIKAHPWTKVFRA--------RTPPEAIALCSRLLEYTPTSRLTPLDACAH 337
> hsa:2931 GSK3A, DKFZp686D0638; glycogen synthase kinase 3 alpha
(EC:2.7.11.26); K08822 glycogen synthase kinase 3 alpha
[EC:2.7.11.26]
Length=483
Score = 356 bits (913), Expect = 1e-97, Method: Compositional matrix adjust.
Identities = 172/303 (56%), Positives = 226/303 (74%), Gaps = 15/303 (4%)
Query 19 QQPQKSYDMG----QVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALE 74
Q P++S ++ +V+GNGSFGVV +AR ET E VAIKKVLQD R+KNREL+IM+ L+
Sbjct 109 QGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLD 168
Query 75 HPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYT 134
H NIVRL +FY+ E++ + +LN+V+E+VPETVYRV + F K+ +P + +K+Y
Sbjct 169 HCNIVRLRYFFYSSGEKKDEL--YLNLVLEYVPETVYRVARHFTKAKL-TIPILYVKVYM 225
Query 135 YQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFY 194
YQ+ RSL Y+H+ G+CHRD+KPQNLLVD T VLKLCDFGSAK+LV GE +V+YICSR+Y
Sbjct 226 YQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYY 285
Query 195 RAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMS 254
RAPEL+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 286 RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIR 345
Query 255 AMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEA 314
MNPNY EF+FP +K W VF S ++ +A+ L S LL Y P RL PLEA
Sbjct 346 EMNPNYTEFKFPQIKAHPWTKVFKS--------RTPPEAIALCSSLLEYTPSSRLSPLEA 397
Query 315 LAH 317
AH
Sbjct 398 CAH 400
> dre:30654 gsk3b, GSK-3[b], GSK3, fk80d11, wu:fb68h05, wu:fk80d11;
glycogen synthase kinase 3 beta (EC:2.7.11.26); K03083
glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=421
Score = 355 bits (912), Expect = 1e-97, Method: Compositional matrix adjust.
Identities = 183/363 (50%), Positives = 246/363 (67%), Gaps = 29/363 (7%)
Query 17 GMQQPQK-SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEH 75
G +PQ+ SY +V+GNGSFGVV +A+ ++GE VAIKKVLQD R+KNREL+IM+ L+H
Sbjct 47 GPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDH 106
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
NIVRL +FY+ +++ + +LN+V+++VPETVYRV + + ++ LP + +KLY Y
Sbjct 107 CNIVRLRYFFYSSGDKKDEV--YLNLVLDYVPETVYRVARHYSRAK-QTLPMVYVKLYMY 163
Query 136 QMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYR 195
Q+ RSL Y+H+ GICHRD+KPQNLL+D T VLKLCDFGSAK+LV GE +V+YICSR+YR
Sbjct 164 QLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYR 223
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSA 255
APEL+ GA +YT++ID+WS GCVL ELLLG+P+F G++ VDQLV+II++LGTPTR Q+
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query 256 MNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
MNPNY EF+FP +K W VF ++ +A+ L S+LL Y P RL PLEA
Sbjct 284 MNPNYTEFKFPQIKAHPWTKVFRP--------RTPPEAIALCSRLLEYTPTARLTPLEAC 335
Query 316 AH-----LEESEEKFRGDRRAIAFFAALIMVGVFLMFYFTTTRLEQSIKEASKLLGPTPR 370
AH L E K R + +F FTT L + AS L+ R
Sbjct 336 AHSFFDELREPNVKLPNGREKPS------------LFNFTTQELSSNPTLASILIPAHAR 383
Query 371 PEA 373
+A
Sbjct 384 NQA 386
> ath:AT5G14640 SK13; SK13 (SHAGGY-LIKE KINASE 13); ATP binding
/ protein kinase/ protein serine/threonine kinase; K03083
glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=410
Score = 355 bits (911), Expect = 1e-97, Method: Compositional matrix adjust.
Identities = 169/301 (56%), Positives = 225/301 (74%), Gaps = 15/301 (4%)
Query 20 QPQK--SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPN 77
QP++ SY +++G GSFG+V +A+CLETGE VAIKKVLQD RYKNREL+ M+ L+HPN
Sbjct 67 QPKQTISYMAERIVGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKNRELQTMRLLDHPN 126
Query 78 IVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQM 137
+V L F++ E+ +LN+V+E+VPETVYRV K + +++ +P I +KLYTYQ+
Sbjct 127 VVSLKHCFFSTTEKD---ELYLNLVLEYVPETVYRVSKHYSRAN-QRMPIIYVKLYTYQI 182
Query 138 CRSLGYLHA-LGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRA 196
CR+L Y+H +G+CHRD+KPQNLLV+ TH +KLCDFGSAK LV GE +++YICSR+YRA
Sbjct 183 CRALAYIHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRA 242
Query 197 PELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAM 256
PEL+ GA EYTT IDIWS GCVL ELLLG+PLF GE+ VDQLV+II++LGTPTR ++ M
Sbjct 243 PELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM 302
Query 257 NPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
NPNY EF+FP +K W +F ++ +AVDL+S+LL+Y P R +EA+
Sbjct 303 NPNYTEFKFPQIKAHPWHKIFHK--------RTPPEAVDLVSRLLQYSPNLRSTAMEAIV 354
Query 317 H 317
H
Sbjct 355 H 355
> ath:AT3G61160 shaggy-related protein kinase beta / ASK-beta
(ASK2)
Length=431
Score = 354 bits (908), Expect = 3e-97, Method: Compositional matrix adjust.
Identities = 166/295 (56%), Positives = 220/295 (74%), Gaps = 13/295 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY V+G GSFGVV +A+CLET E+VAIKKVLQD RYKNREL+IM+ L+HPN+V L
Sbjct 101 SYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKNRELQIMRMLDHPNVVELKH 160
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
F++ E+ +LN+V+E+VPET+YR +S+ K + H +P I I+LYTYQ+CR++ Y
Sbjct 161 SFFSTTEKD---ELYLNLVLEYVPETIYRASRSYTKMNQH-MPLIYIQLYTYQICRAMNY 216
Query 144 LH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
LH +G+CHRD+KPQNLLV+ TH +K+CDFGSAK L+PGE +++YICSR+YRAPEL+ G
Sbjct 217 LHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIPGEPNISYICSRYYRAPELIFG 276
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A EYT+AID+WS+GCV+ EL LG PLF GETSVDQLV+II+ILGTP R ++ MNP Y +
Sbjct 277 ATEYTSAIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMNPRYND 336
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
F+FP +K + W +F + +A+DL S+LL+Y P R LEA AH
Sbjct 337 FKFPQIKAQPWHKIFRR--------QVSPEAMDLASRLLQYSPNLRCTALEACAH 383
> ath:AT1G09840 ATSK41; ATSK41 (SHAGGY-LIKE PROTEIN KINASE 41);
ATP binding / protein kinase/ protein serine/threonine kinase
Length=421
Score = 350 bits (897), Expect = 7e-96, Method: Compositional matrix adjust.
Identities = 170/306 (55%), Positives = 220/306 (71%), Gaps = 13/306 (4%)
Query 13 RSASGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKA 72
R +G + SY V+G GSFG+V +A+C ETGE VAIKKVLQD RYKNREL+IM+
Sbjct 71 RGRNGQSRQTVSYISEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQM 130
Query 73 LEHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKL 132
L+HPN V L F++ + +LN+V+EFVPETV RV +S+ +++ +P I +KL
Sbjct 131 LDHPNAVALKHSFFSRTDNE---EVYLNLVLEFVPETVNRVARSYSRTN-QLMPLIYVKL 186
Query 133 YTYQMCRSLGYLH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICS 191
YTYQ+CR+L Y+H + G+CHRD+KPQNLLV+ TH LK+CDFGSAK LV GE +V+YICS
Sbjct 187 YTYQICRALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVSYICS 246
Query 192 RFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRC 251
R+YRAPEL+ GA+EYTTAIDIWS GCV+ ELLLG+PLF GE+ VDQLV+II++LGTPTR
Sbjct 247 RYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTRE 306
Query 252 QMSAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQP 311
++ MNPNY EF+FP +KP W VF + +AVDL+ + +Y P R
Sbjct 307 EIKCMNPNYTEFKFPQIKPHPWHKVFQK--------RLPPEAVDLLCRFFQYSPNLRCTA 358
Query 312 LEALAH 317
LEA H
Sbjct 359 LEACIH 364
> ath:AT3G05840 ATSK12; ATSK12; protein kinase/ protein serine/threonine
kinase
Length=409
Score = 348 bits (893), Expect = 2e-95, Method: Compositional matrix adjust.
Identities = 170/301 (56%), Positives = 225/301 (74%), Gaps = 15/301 (4%)
Query 20 QPQK--SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPN 77
QP++ SY +V+G+GSFGVV +A+CLETGE VAIKKVLQD RYKNREL+ M+ L+HPN
Sbjct 66 QPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPN 125
Query 78 IVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQM 137
+V L F++ E+ +LN+V+E+VPETV+RV+K + K + +P + +KLYTYQ+
Sbjct 126 VVSLKHCFFSTTEKD---ELYLNLVLEYVPETVHRVIKHYNKLN-QRMPLVYVKLYTYQI 181
Query 138 CRSLGYLH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRA 196
RSL Y+H +G+CHRD+KPQNLLV+ TH +KLCDFGSAK LV GE +++YICSR+YRA
Sbjct 182 FRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRA 241
Query 197 PELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAM 256
PEL+ GA EYTTAID+WS GCVL ELLLG+PLF GE+ VDQLV+II++LGTPTR ++ M
Sbjct 242 PELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM 301
Query 257 NPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
NPNY EF+FP +K W +F + +AVDL+S+LL+Y P R L++L
Sbjct 302 NPNYTEFKFPQIKAHPWHKIFHK--------RMPPEAVDLVSRLLQYSPNLRCAALDSLV 353
Query 317 H 317
H
Sbjct 354 H 354
> ath:AT2G30980 ASKdZeta (Arabidopsis SHAGGY-related protein kinase
dZeta); ATP binding / kinase/ protein kinase/ protein
serine/threonine kinase; K00924 [EC:2.7.1.-]
Length=412
Score = 348 bits (893), Expect = 2e-95, Method: Compositional matrix adjust.
Identities = 172/295 (58%), Positives = 215/295 (72%), Gaps = 13/295 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY +V+G GSFG+V +A+CLETGE VAIKKVLQD RYKNREL++M+ ++HPN+V L
Sbjct 71 SYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRLMDHPNVVSLKH 130
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
F++ FLN+VME+VPET+YRV+K + SS +P +KLYTYQ+ R L Y
Sbjct 131 CFFSTTTRD---ELFLNLVMEYVPETLYRVLKHYT-SSNQRMPIFYVKLYTYQIFRGLAY 186
Query 144 LH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
+H A G+CHRDVKPQNLLVD TH KLCDFGSAK LV GE +++YICSR+YRAPEL+ G
Sbjct 187 IHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFG 246
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A EYT++IDIWS GCVL ELLLG+PLF GE SVDQLV+II++LGTPTR ++ MNPNY +
Sbjct 247 ATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTD 306
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
FRFP +K W VF + +A+DL S+LL+Y P R LEA AH
Sbjct 307 FRFPQIKAHPWHKVFHK--------RMPPEAIDLASRLLQYSPSLRCTALEACAH 353
> ath:AT1G06390 GSK1; GSK1 (GSK3/SHAGGY-LIKE PROTEIN KINASE 1);
glycogen synthase kinase 3/ kinase
Length=407
Score = 348 bits (893), Expect = 2e-95, Method: Compositional matrix adjust.
Identities = 169/295 (57%), Positives = 215/295 (72%), Gaps = 13/295 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY +V+G GSFG+V +A+CLETGE VAIKKVLQD RYKNREL++M+ ++HPN++ L
Sbjct 69 SYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMRPMDHPNVISLKH 128
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
F++ FLN+VME+VPET+YRV++ + SS +P +KLYTYQ+ R L Y
Sbjct 129 CFFSTTSRD---ELFLNLVMEYVPETLYRVLRHYT-SSNQRMPIFYVKLYTYQIFRGLAY 184
Query 144 LHAL-GICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
+H + G+CHRDVKPQNLLVD TH +KLCDFGSAK LV GE +++YICSR+YRAPEL+ G
Sbjct 185 IHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFG 244
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A EYT +IDIWS GCVL ELLLG+PLF GE SVDQLV+II++LGTPTR ++ MNPNY +
Sbjct 245 ATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTD 304
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
FRFP +K W VF + +A+DL S+LL+Y P R LEA AH
Sbjct 305 FRFPQIKAHPWHKVFHK--------RMPPEAIDLASRLLQYSPSLRCTALEACAH 351
> ath:AT1G57870 ATSK42; ATSK42 (ARABIDOPSIS SHAGGY-LIKE KINASE
42); ATP binding / protein kinase/ protein serine/threonine
kinase; K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=420
Score = 346 bits (888), Expect = 7e-95, Method: Compositional matrix adjust.
Identities = 169/303 (55%), Positives = 215/303 (70%), Gaps = 13/303 (4%)
Query 16 SGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEH 75
+G + SY V+G GSFG+V +A+C ETGE VAIKKVLQD RYKNREL+IM+ L+H
Sbjct 73 NGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQMLDH 132
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
PN+V L FY+ E +LN+V+EFVPETV R +S+ + + +P I +KLYTY
Sbjct 133 PNVVCLKHSFYSRTENE---EVYLNLVLEFVPETVNRTARSYSRMN-QLMPLIYVKLYTY 188
Query 136 QMCRSLGYLH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFY 194
Q+CR L YLH G+CHRD+KPQNLLV+ TH LK+CDFGSAK LV GE +++YICSR+Y
Sbjct 189 QICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYY 248
Query 195 RAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMS 254
RAPEL+ GA EYTTAIDIWS GCV+ ELLLG+PLF GE+ VDQLV+II++LGTPTR ++
Sbjct 249 RAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIK 308
Query 255 AMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEA 314
MNPNY EF+FP +KP W VF + +AVDL+ + +Y P R +EA
Sbjct 309 CMNPNYTEFKFPQIKPHPWHKVFQK--------RLPPEAVDLLCRFFQYSPNLRCTAVEA 360
Query 315 LAH 317
H
Sbjct 361 CIH 363
> ath:AT5G26751 ATSK11; ATSK11; protein kinase/ protein serine/threonine
kinase; K00924 [EC:2.7.1.-]
Length=405
Score = 346 bits (888), Expect = 8e-95, Method: Compositional matrix adjust.
Identities = 170/301 (56%), Positives = 224/301 (74%), Gaps = 15/301 (4%)
Query 20 QPQK--SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPN 77
QP++ SY +V+G+GSFGVV +A+CLETGE VAIKKVLQD RYKNREL+ M+ L+HPN
Sbjct 62 QPKQTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPN 121
Query 78 IVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQM 137
+V L F++ E+ +LN+V+E+VPETV+RV+K + K + +P I +KLYTYQ+
Sbjct 122 VVSLKHCFFSTTEKD---ELYLNLVLEYVPETVHRVIKHYNKLN-QRMPLIYVKLYTYQI 177
Query 138 CRSLGYLH-ALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRA 196
R+L Y+H +G+CHRD+KPQNLLV+ TH +KLCDFGSAK LV GE +++YICSR+YRA
Sbjct 178 FRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRA 237
Query 197 PELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAM 256
PEL+ GA EYTTAID+WS GCVL ELLLG+PLF GE+ VDQLV+II++LGTPTR ++ M
Sbjct 238 PELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCM 297
Query 257 NPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
NPNY EF+FP +K W +F + +AVDL+S+LL+Y P R L+ L
Sbjct 298 NPNYTEFKFPQIKAHPWHKIFHK--------RMPPEAVDLVSRLLQYSPNLRSAALDTLV 349
Query 317 H 317
H
Sbjct 350 H 350
> cel:Y18D10A.5 gsk-3; Glycogen Synthase Kinase family member
(gsk-3); K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26]
Length=362
Score = 343 bits (880), Expect = 6e-94, Method: Compositional matrix adjust.
Identities = 164/299 (54%), Positives = 216/299 (72%), Gaps = 11/299 (3%)
Query 19 QQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNI 78
QQ + SY +V+GNGSFGVV A+ T E VAIKKVLQD R+KNREL+IM+ L HPNI
Sbjct 30 QQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPNI 89
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
V+L +FY+ E++ + +LN+++E+VPETVYRV + + K +P I +KLY YQ+
Sbjct 90 VKLKYFFYSSGEKKDEL--YLNLILEYVPETVYRVARHYSKQR-QQIPMIYVKLYMYQLL 146
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPE 198
RSL Y+H++GICHRD+KPQNLL+D + VLKLCDFGSAK LV E +V+YICSR+YRAPE
Sbjct 147 RSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPE 206
Query 199 LMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNP 258
L+ GA YT +ID+WS G V+ ELLLG+P+F G++ VDQLV+II++LGTPTR Q+ +MNP
Sbjct 207 LIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNP 266
Query 259 NYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
NY EF+FP +K W VF H A +A+DL+SK++ Y P R P A H
Sbjct 267 NYKEFKFPQIKAHPWNKVFRVHTPA--------EAIDLISKIIEYTPTSRPTPQAACQH 317
> ath:AT4G18710 BIN2; BIN2 (BRASSINOSTEROID-INSENSITIVE 2); glycogen
synthase kinase 3/ kinase/ protein kinase; K14502 protein
brassinosteroid insensitive 2 [EC:2.7.11.1]
Length=380
Score = 343 bits (879), Expect = 8e-94, Method: Compositional matrix adjust.
Identities = 164/295 (55%), Positives = 217/295 (73%), Gaps = 13/295 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY +V+G GSFG+V +A+CLETGE VAIKKVLQD RYKNREL++M+ ++HPN+V L
Sbjct 39 SYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVVCLKH 98
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
F++ + FLN+VME+VPE++YRV+K + S+ +P + +KLY YQ+ R L Y
Sbjct 99 CFFSTTSKD---ELFLNLVMEYVPESLYRVLKHY-SSANQRMPLVYVKLYMYQIFRGLAY 154
Query 144 LHAL-GICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
+H + G+CHRD+KPQNLLVD TH +K+CDFGSAK+LV GE +++YICSRFYRAPEL+ G
Sbjct 155 IHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICSRFYRAPELIFG 214
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A EYTT+IDIWS GCVL ELLLG+PLF GE +VDQLV+II++LGTPTR ++ MNP+Y +
Sbjct 215 ATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTD 274
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
FRFP +K W +F + +A+D S+LL+Y P R LEA AH
Sbjct 275 FRFPQIKAHPWHKIFHK--------RMPPEAIDFASRLLQYSPSLRCTALEACAH 321
> sce:YMR139W RIM11, GSK3, MDS1; Protein kinase required for signal
transduction during entry into meiosis; promotes the formation
of the Ime1p-Ume6p complex by phosphorylating Ime1p
and Ume6p; shares similarity with mammalian glycogen synthase
kinase 3-beta (EC:2.7.11.1); K12766 serine/threonine-protein
kinase MDS1/RIM11 [EC:2.7.11.1]
Length=370
Score = 303 bits (775), Expect = 9e-82, Method: Compositional matrix adjust.
Identities = 148/296 (50%), Positives = 207/296 (69%), Gaps = 14/296 (4%)
Query 22 QKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRL 81
Q S+ +V+G+GSFGVV ET E+VAIKKVLQD R+KNRELEIMK L H NI+ L
Sbjct 36 QISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDL 95
Query 82 LDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSL 141
YF+ E + + I +LN+++E++P+++Y+ ++ F+ T + + IK Y +Q+ +SL
Sbjct 96 -KYFFYERDSQDEI--YLNLILEYMPQSLYQRLRHFVHQRT-PMSRLEIKYYMFQLFKSL 151
Query 142 GYLHALG-ICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELM 200
YLH +CHRD+KPQNLLVD T LKLCDFGSAK+L P E +V+YICSR+YRAPEL+
Sbjct 152 NYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELI 211
Query 201 LGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNY 260
GA YT IDIWS GCV+ ELLLG+P+F GE+ +DQLV+II+ILGTP++ ++ +MNPNY
Sbjct 212 FGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNY 271
Query 261 LEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
+E +FP +KP VF D +Q V+ ++ +L+Y+P +R L+ L
Sbjct 272 MEHKFPQIKPIPLSRVFKKED---------DQTVEFLADVLKYDPLERFNALQCLC 318
> sce:YDL079C MRK1; Glycogen synthase kinase 3 (GSK-3) homolog;
one of four GSK-3 homologs in S. cerevisiae that function
to activate Msn2p-dependent transcription of stress responsive
genes and that function in protein degradation (EC:2.7.11.1);
K08282 non-specific serine/threonine protein kinase [EC:2.7.11.1]
Length=501
Score = 302 bits (774), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 146/293 (49%), Positives = 203/293 (69%), Gaps = 14/293 (4%)
Query 24 SYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
SY +V+G+GSFGVV +ET ++VAIKKVLQD RYKNRELE MK L HPN V L
Sbjct 163 SYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQY 222
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
YFY + EE +LN+V++++P+++Y+ ++ F+ +P + IK Y YQ+ ++L Y
Sbjct 223 YFYEKDEED---EVYLNLVLDYMPQSLYQRLRHFVNLKMQ-MPRVEIKFYAYQLFKALNY 278
Query 144 LHALG-ICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLG 202
LH + ICHRD+KPQNLLVD T K+CDFGSAK L P + +V+YICSR+YRAPELM G
Sbjct 279 LHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFG 338
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A Y+ +D+WS CV+ ELLLG+PLF+GE+ +DQLV+II+I+G PT+ ++S MNPNY +
Sbjct 339 ATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYED 398
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
FP++KP +F + D +DL++K L+Y P +RL PL+ L
Sbjct 399 HVFPNIKPITLAEIFKAED---------PDTLDLLTKTLKYHPCERLVPLQCL 442
> cel:C44H4.6 hypothetical protein; K03083 glycogen synthase kinase
3 beta [EC:2.7.11.26]
Length=367
Score = 232 bits (591), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 119/288 (41%), Positives = 175/288 (60%), Gaps = 15/288 (5%)
Query 29 QVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLDYFYTE 88
Q++G GSFG V +A E E +AIKK+ D R+K+REL IM ++HPNI+RLL Y+ +
Sbjct 41 QLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDRFKSRELTIMHEMDHPNIIRLLYYYVMQ 100
Query 89 VEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYLHALG 148
E LN VMEF+P+ + V + F + +P IKLY +Q+ R +G+LH
Sbjct 101 QEN------CLNFVMEFMPKDLAYVHRQFAHNDKQ-MPAYSIKLYMFQLLRGIGFLHLHN 153
Query 149 ICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLGANEYTT 208
I HRD+KP+NLLVD +LK+CDFGSAKRL E ++ YICSR+YRAPEL+ G+ Y T
Sbjct 154 IVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNEPNITYICSRYYRAPELIFGSKNYDT 213
Query 209 AIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLEFRFPDV 268
+ID WS+G V+GELL P+F +++VD L I+ GTP++ M+ N Y+ + +
Sbjct 214 SIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAKWNYEYVHIPYDTI 273
Query 269 KPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALA 316
+ G K ++L++ L++ +P+ R++P EAL
Sbjct 274 TGVGIQKFI--------GRKLSLSTLELLNSLMKMDPKLRIKPYEALT 313
> sce:YNL307C MCK1, CMS1, YPK1; Mck1p (EC:2.7.12.1); K00924 [EC:2.7.1.-]
Length=375
Score = 231 bits (589), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 125/299 (41%), Positives = 184/299 (61%), Gaps = 27/299 (9%)
Query 31 LGNGSFGVVTEARCLETGER----VAIKKVLQDPRYKNRELEIMKALEHPNIVRLLDYFY 86
+G G+FG V +A + + AIKKV YK+REL+I++ +HPNIV+L YF+
Sbjct 41 IGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKL-QYFF 99
Query 87 TEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYLHA 146
T + + + + ++ ME +PET+ + ++ + +P I+LYTYQ+ R + YLH
Sbjct 100 THLSPQDN-KVYQHLAMECLPETLQIEINRYVTNKLE-MPLKHIRLYTYQIARGMLYLHG 157
Query 147 LGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELMLGANEY 206
LG+CHRD+KP N+LVD T VLK+CDFGSAK+L + S++YICSRFYRAPEL++G +Y
Sbjct 158 LGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQY 217
Query 207 TTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLEFRFP 266
TT IDIW LGCV+GE+L+G+ +F G+ + QL +I ++LG P + + NP Y
Sbjct 218 TTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAY------ 271
Query 267 DVKPKDWKAVFASHDCALGGDKSFEQ--------AVDLMSKLLRYEPEQRLQPLEALAH 317
P K +F+ + FE+ +DL+ K+L YEP+QRL P LAH
Sbjct 272 -DGPLFSKPLFSG-----SSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAH 324
> sce:YOL128C YGK3; Protein kinase related to mammalian glycogen
synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p,
Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent
transcription of stress responsive genes and in protein
degradation (EC:2.7.11.1); K08286 protein-serine/threonine
kinase [EC:2.7.11.-]
Length=375
Score = 196 bits (497), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 109/296 (36%), Positives = 178/296 (60%), Gaps = 19/296 (6%)
Query 28 GQVLGNGSFGVVTEA----RCLETGERVAIKKVLQDPRYKNRELEIMKALEHPNIVRLLD 83
G+ +G+GSFG VT++ +E AIK+V++ P+ ++ ELEI++ + HPN+V L
Sbjct 44 GKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSPKVQSLELEILQNIRHPNLVTLEF 103
Query 84 YF--YTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSL 141
+F + ++ G + + N VME++P+T+ + + + + +P IKLYT+Q+ R+L
Sbjct 104 FFESHCTTKDGGHLYQ-KNFVMEYIPQTLSSEIHEYFDNGS-KMPTKHIKLYTFQILRAL 161
Query 142 GYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVAYICSRFYRAPELML 201
LH++ ICH D+KP N+L+ + + K+CDFGSA+RL + Y CSRFYRAPEL+L
Sbjct 162 LTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLDDNTELKTYFCSRFYRAPELLL 221
Query 202 GANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYL 261
+ +YTT IDIWSLGC++GE++ G+PLF G+++ QL +I ++LG + S N L
Sbjct 222 NSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEEIAKLLGRFPKS--SIKNSQEL 279
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ D K K + F S + V+ + K+L Y+ +R + +AH
Sbjct 280 QDSLNDQKFKKFMHWFPSIEFF---------DVEFLLKVLTYDATERCDARQLMAH 326
> hsa:1017 CDK2, p33(CDK2); cyclin-dependent kinase 2 (EC:2.7.11.22);
K02206 cyclin-dependent kinase 2 [EC:2.7.11.22]
Length=298
Score = 184 bits (467), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 109/296 (36%), Positives = 166/296 (56%), Gaps = 31/296 (10%)
Query 31 LGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNIVRLLDY 84
+G G++GVV +AR TGE VA+KK+ D P RE+ ++K L HPNIV+LLD
Sbjct 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
Query 85 FYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYL 144
+TE + L +V EF+ + + + M + S+ +P LIK Y +Q+ + L +
Sbjct 70 IHTENK--------LYLVFEFLHQDLKKFMDA---SALTGIPLPLIKSYLFQLLQGLAFC 118
Query 145 HALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLGA 203
H+ + HRD+KPQNLL++ +KL DFG A+ VP + + +YRAPE++LG
Sbjct 119 HSHRVLHRDLKPQNLLINTEG-AIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGC 177
Query 204 NEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN--PNYL 261
Y+TA+DIWSLGC+ E++ R LF G++ +DQL +I + LGTP + P+Y
Sbjct 178 KYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY- 236
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ FP +D+ V D E L+S++L Y+P +R+ ALAH
Sbjct 237 KPSFPKWARQDFSKVVPPLD---------EDGRSLLSQMLHYDPNKRISAKAALAH 283
> ath:AT3G48750 CDC2; CDC2 (CELL DIVISION CONTROL 2); cyclin-dependent
protein kinase/ kinase/ protein binding / protein kinase;
K02087 cyclin-dependent kinase 1 [EC:2.7.11.22]
Length=294
Score = 184 bits (466), Expect = 6e-46, Method: Compositional matrix adjust.
Identities = 105/302 (34%), Positives = 170/302 (56%), Gaps = 30/302 (9%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNI 78
Y+ + +G G++GVV +AR T E +A+KK+ + P RE+ ++K ++H NI
Sbjct 4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNI 63
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
V+L D ++E + L +V E++ + + M S + + +IK Y YQ+
Sbjct 64 VKLQDVVHSE--------KRLYLVFEYLDLDLKKHMDS---TPDFSKDLHMIKTYLYQIL 112
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAP 197
R + Y H+ + HRD+KPQNLL+D RT+ LKL DFG A+ +P + + +YRAP
Sbjct 113 RGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAP 172
Query 198 ELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN 257
E++LG++ Y+T +DIWS+GC+ E++ +PLF G++ +DQL KI +I+GTP +
Sbjct 173 EILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVT 232
Query 258 --PNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
P+Y + FP KP D + + D VDL+SK+L +P +R+ AL
Sbjct 233 SLPDY-KSAFPKWKPTDLETFVPNLD---------PDGVDLLSKMLLMDPTKRINARAAL 282
Query 316 AH 317
H
Sbjct 283 EH 284
> mmu:12566 Cdk2, A630093N05Rik; cyclin-dependent kinase 2 (EC:2.7.11.22);
K02206 cyclin-dependent kinase 2 [EC:2.7.11.22]
Length=298
Score = 183 bits (464), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 108/296 (36%), Positives = 166/296 (56%), Gaps = 31/296 (10%)
Query 31 LGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNIVRLLDY 84
+G G++GVV +A+ TGE VA+KK+ D P RE+ ++K L HPNIV+LLD
Sbjct 10 IGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
Query 85 FYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYL 144
+TE + L +V EF+ + + + M + S+ +P LIK Y +Q+ + L +
Sbjct 70 IHTENK--------LYLVFEFLHQDLKKFMDA---SALTGIPLPLIKSYLFQLLQGLAFC 118
Query 145 HALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLGA 203
H+ + HRD+KPQNLL++ + KL DFG A+ VP + + +YRAPE++LG
Sbjct 119 HSHRVLHRDLKPQNLLINAEGSI-KLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGC 177
Query 204 NEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN--PNYL 261
Y+TA+DIWSLGC+ E++ R LF G++ +DQL +I + LGTP + P+Y
Sbjct 178 KYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY- 236
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ FP +D+ V D E L+S++L Y+P +R+ ALAH
Sbjct 237 KPSFPKWARQDFSKVVPPLD---------EDGRSLLSQMLHYDPNKRISAKAALAH 283
> hsa:1018 CDK3; cyclin-dependent kinase 3 (EC:2.7.11.22); K02088
cyclin-dependent kinase 3 [EC:2.7.11.22]
Length=305
Score = 182 bits (463), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 107/296 (36%), Positives = 170/296 (57%), Gaps = 31/296 (10%)
Query 31 LGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNIVRLLDY 84
+G G++GVV +A+ ETG+ VA+KK+ D P RE+ ++K L+HPNIVRLLD
Sbjct 10 IGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDV 69
Query 85 FYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYL 144
+ E R L +V EF+ + + + M S + LP LIK Y +Q+ + + +
Sbjct 70 VHNE--------RKLYLVFEFLSQDLKKYMDS---TPGSELPLHLIKSYLFQLLQGVSFC 118
Query 145 HALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLGA 203
H+ + HRD+KPQNLL++ +KL DFG A+ VP + + +YRAPE++LG+
Sbjct 119 HSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGS 177
Query 204 NEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN--PNYL 261
YTTA+DIWS+GC+ E++ + LF G++ +DQL +I ++LGTP+ + P+Y
Sbjct 178 KFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY- 236
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ FP K + + + + + DL+ +LL+Y+P QR+ ALAH
Sbjct 237 KGSFPKWTRKGLEEIVPNLE---------PEGRDLLMQLLQYDPSQRITAKTALAH 283
> pfa:PF14_0294 PfMAP1; mitogen-activated protein kinase 1; K04371
extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
Length=914
Score = 182 bits (462), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 103/311 (33%), Positives = 174/311 (55%), Gaps = 38/311 (12%)
Query 23 KSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVL------QDPRYKNRELEIMKALE-H 75
K YD+ + +G G++GVV + RC + VA+KK+ D + RE+ + L H
Sbjct 21 KKYDILKKVGKGAYGVVFKGRCKKNKNIVAVKKIFGAFQNCTDAQRTFREIIFLYELNGH 80
Query 76 PNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTY 135
NI++L+D + + ++ +F+ ++ V+K+ + H I Y
Sbjct 81 DNIIKLMDVI------KAKNDNDIYLIFDFMETDLHEVIKADLLEEIHKKYII------Y 128
Query 136 QMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVP--GEQSV----AYI 189
Q+ R+L Y+H+ G+ HRD+KP N+LV+ H+ K+ DFG A+ + E V Y+
Sbjct 129 QLLRALKYIHSGGLLHRDIKPSNILVNSECHI-KVADFGLARSISTHVNENKVPILTDYV 187
Query 190 CSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPT 249
+R+YRAPE++LG+ YT +D+WSLGC++GELL G+PLF G ++++QL KIIQ++G P
Sbjct 188 ATRWYRAPEILLGSTHYTEDVDMWSLGCIMGELLCGKPLFTGNSTMNQLEKIIQVIGKPN 247
Query 250 RCQMSAMNPNYLE---FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPE 306
+ + + + E F D+K K+ K + C K+ +++DL+ KLL++ P
Sbjct 248 KKDIEDIRSPFAEKIISSFVDLKKKNLKDI-----CY----KASNESLDLLEKLLQFNPS 298
Query 307 QRLQPLEALAH 317
+R+ AL H
Sbjct 299 KRISAENALKH 309
> xla:399314 cdk2, eg1; cyclin-dependent kinase 2 (EC:2.7.11.22);
K02206 cyclin-dependent kinase 2 [EC:2.7.11.22]
Length=297
Score = 182 bits (461), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 106/296 (35%), Positives = 166/296 (56%), Gaps = 31/296 (10%)
Query 31 LGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNIVRLLDY 84
+G G++GVV +AR ETGE VA+KK+ D P RE+ ++K L HPNIV+LLD
Sbjct 10 IGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
Query 85 FYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYL 144
+TE + L +V EF+ + + + M +S+ + L+K Y +Q+ + L +
Sbjct 70 IHTENK--------LYLVFEFLNQDLKKFMD---RSNISGISLALVKSYLFQLLQGLAFC 118
Query 145 HALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLGA 203
H+ + HRD+KPQNLL++ +KL DFG A+ VP + + +YRAPE++LG
Sbjct 119 HSHRVLHRDLKPQNLLIN-SDGAIKLADFGLARAFGVPVRTFTHEVVTLWYRAPEILLGC 177
Query 204 NEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN--PNYL 261
Y+TA+DIWSLGC+ E++ R LF G++ +DQL +I + LGTP + P+Y
Sbjct 178 KFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDY- 236
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ FP +D+ V D E DL++++L+Y+ +R+ AL H
Sbjct 237 KSTFPKWIRQDFSKVVPPLD---------EDGRDLLAQMLQYDSNKRISAKVALTH 283
> dre:406715 cdk2, wu:fa10c02, zgc:56598, zgc:77684; cyclin-dependent
kinase 2 (EC:2.7.1.-); K02206 cyclin-dependent kinase
2 [EC:2.7.11.22]
Length=298
Score = 181 bits (459), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 107/302 (35%), Positives = 166/302 (54%), Gaps = 27/302 (8%)
Query 23 KSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHP 76
+S+ + +G G++GVV +A+ TGE VA+KK+ D P RE+ ++K L HP
Sbjct 2 ESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHP 61
Query 77 NIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQ 136
NIV+L D +TE + L +V EF+ + + R M S +S + L+K Y +Q
Sbjct 62 NIVKLRDVIHTENK--------LYLVFEFLHQDLKRFMDS---TSVSGISLPLVKSYLFQ 110
Query 137 MCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYR 195
+ + L + H+ + HRD+KPQNLL++ + + KL DFG A+ VP + + +YR
Sbjct 111 LLQGLAFCHSHRVLHRDLKPQNLLINAQGEI-KLADFGLARAFGVPVRTYTHEVVTLWYR 169
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSA 255
APE++LG Y+TA+DIWSLGC+ E++ R LF G++ +DQL +I + LGTP
Sbjct 170 APEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDESIWPG 229
Query 256 MNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEAL 315
+ PD KP K +A D + E DL+ ++L Y+P +R+ AL
Sbjct 230 VT------SMPDYKPSFPK--WARQDLSKVVPPLDEDGRDLLGQMLTYDPNKRISAKNAL 281
Query 316 AH 317
H
Sbjct 282 VH 283
> mmu:23939 Mapk7, BMK1, ERK5, Erk5-T, PRKM7; mitogen-activated
protein kinase 7 (EC:2.7.11.24); K04464 mitogen-activated
protein kinase 7 [EC:2.7.11.24]
Length=806
Score = 179 bits (455), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 110/308 (35%), Positives = 173/308 (56%), Gaps = 33/308 (10%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKK------VLQDPRYKNRELEIMKALEHPNI 78
Y++ + +GNG++GVV+ AR TG++VAIKK V+ + + REL+I+K +H NI
Sbjct 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 114
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
+ + D V G R + VV++ + +++++ S + L ++ + YQ+
Sbjct 115 IAIKDILKPTVP-YGEF-RSVYVVLDLMESDLHQIIHS-----SQPLTLEHVRYFLYQLL 167
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLV--PGEQS---VAYICSRF 193
R L Y+H+ + HRD+KP NLLV+ LK+ DFG A+ L P E Y+ +R+
Sbjct 168 RGLKYMHSAQVIHRDLKPSNLLVNENCE-LKIGDFGMARGLCTSPAEHQYFMTEYVATRW 226
Query 194 YRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQM 253
YRAPELML +EYT AID+WS+GC+ GE+L R LF G+ V QL I+ +LGTP+ +
Sbjct 227 YRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVI 286
Query 254 SAMNPN----YLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRL 309
A+ Y++ P +P W+ V+ D QA+ L+ ++LR+EP R+
Sbjct 287 QAVGAERVRAYIQ-SLPPRQPVPWETVYPGAD---------RQALSLLGRMLRFEPSARI 336
Query 310 QPLEALAH 317
AL H
Sbjct 337 SAAAALRH 344
> hsa:5598 MAPK7, BMK1, ERK4, ERK5, PRKM7; mitogen-activated protein
kinase 7 (EC:2.7.11.24); K04464 mitogen-activated protein
kinase 7 [EC:2.7.11.24]
Length=816
Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 109/308 (35%), Positives = 173/308 (56%), Gaps = 33/308 (10%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKK------VLQDPRYKNRELEIMKALEHPNI 78
Y++ + +GNG++GVV+ AR TG++VAIKK V+ + + REL+I+K +H NI
Sbjct 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNI 114
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
+ + D V G + + VV++ + +++++ S + L ++ + YQ+
Sbjct 115 IAIKDILRPTVP-YGEF-KSVYVVLDLMESDLHQIIHS-----SQPLTLEHVRYFLYQLL 167
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLV--PGEQS---VAYICSRF 193
R L Y+H+ + HRD+KP NLLV+ LK+ DFG A+ L P E Y+ +R+
Sbjct 168 RGLKYMHSAQVIHRDLKPSNLLVNENCE-LKIGDFGMARGLCTSPAEHQYFMTEYVATRW 226
Query 194 YRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQM 253
YRAPELML +EYT AID+WS+GC+ GE+L R LF G+ V QL I+ +LGTP+ +
Sbjct 227 YRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVI 286
Query 254 SAMNPN----YLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRL 309
A+ Y++ P +P W+ V+ D QA+ L+ ++LR+EP R+
Sbjct 287 QAVGAERVRAYIQ-SLPPRQPVPWETVYPGAD---------RQALSLLGRMLRFEPSARI 336
Query 310 QPLEALAH 317
AL H
Sbjct 337 SAAAALRH 344
> xla:432036 hypothetical protein MGC81499; K02206 cyclin-dependent
kinase 2 [EC:2.7.11.22]
Length=297
Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 104/296 (35%), Positives = 165/296 (55%), Gaps = 31/296 (10%)
Query 31 LGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHPNIVRLLDY 84
+G G++GVV +AR +TGE VA+KK+ D P RE+ ++K L HPNIV+LLD
Sbjct 10 IGEGTYGVVYKARNRDTGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDV 69
Query 85 FYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYL 144
+TE + L +V EF+ + + + M + S+ + L+K Y +Q+ + L +
Sbjct 70 IHTENK--------LYLVFEFLNQDLKKFMDA---SNISGISLALVKSYLFQLLQGLAFC 118
Query 145 HALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLGA 203
H+ + HRD+KPQNLL++ +KL DFG A+ VP + + +Y APE++LG
Sbjct 119 HSHRVLHRDLKPQNLLIN-SDGAIKLADFGLARAFGVPVRTYTHEVVTLWYTAPEILLGC 177
Query 204 NEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMN--PNYL 261
Y+TA+DIWSLGC+ E++ R LF G++ +DQL +I + LGTP + P+Y
Sbjct 178 KFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDY- 236
Query 262 EFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+ FP +D+ V D E DL++++L+Y+ +R+ AL H
Sbjct 237 KSTFPKWIRQDFSKVVPPLD---------EDGRDLLAQMLQYDSNKRISAKAALTH 283
> ath:AT1G66750 CAK4; CAK4 (CDK-ACTIVATING KINASE 4); kinase/
protein binding / protein serine/threonine kinase; K02202 cyclin-dependent
kinase 7 [EC:2.7.11.22]
Length=348
Score = 176 bits (445), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 115/320 (35%), Positives = 162/320 (50%), Gaps = 47/320 (14%)
Query 14 SASGMQQPQKSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKN--------- 64
S SG QP Y Q+LG G++GVV +A +TG+ VA+KK+ R N
Sbjct 2 SKSGDNQPVDRYLRRQILGEGTYGVVYKATDTKTGKTVAVKKI----RLGNQKEGVNFTA 57
Query 65 -RELEIMKALEHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVP---ETVYRVMKSFIKS 120
RE++++K L HP+IV L+D F GS L++V E++ E V R F+
Sbjct 58 LREIKLLKELNHPHIVELIDAF----PHDGS----LHLVFEYMQTDLEAVIRDRNIFLSP 109
Query 121 STHALPFILIKLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL- 179
IK Y + L Y H + HRD+KP NLL+ +LKL DFG A+
Sbjct 110 GD-------IKSYMLMTLKGLAYCHKKWVLHRDMKPNNLLIG-ENGLLKLADFGLARLFG 161
Query 180 VPGEQSVAYICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLV 239
P + + + +YRAPEL+ G+ +Y +D+W+ GC+ ELLL RP G T +DQL
Sbjct 162 SPNRRFTHQVFATWYRAPELLFGSRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLG 221
Query 240 KIIQILGTPTRCQMSAMN--PNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLM 297
KI Q GTP Q S M P+Y+EF + P AS D A+DL+
Sbjct 222 KIFQAFGTPVPSQWSDMIYLPDYMEFSYTPAPPLRTIFPMASDD-----------ALDLL 270
Query 298 SKLLRYEPEQRLQPLEALAH 317
+K+ Y+P QR+ +AL H
Sbjct 271 AKMFIYDPRQRITIQQALDH 290
> tgo:TGME49_085160 cyclin-dependent kinase-like 5, putative (EC:2.7.11.22);
K08824 cyclin-dependent kinase-like [EC:2.7.11.22]
Length=351
Score = 174 bits (441), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 110/307 (35%), Positives = 170/307 (55%), Gaps = 37/307 (12%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKN------RELEIMKALEHPNI 78
Y+ +++G G++GVV + R +TGE VAIK + N REL + L H NI
Sbjct 4 YEKLELVGEGAYGVVLKCRRKDTGELVAIKTFKGNEESTNVKKTIARELNALTHLRHENI 63
Query 79 VRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMC 138
V L + F + + L++V E++ +R + +++S L ++L +Q+
Sbjct 64 VALKEAFRWKGK--------LHLVFEYI----HRNLLELLEASPAGLDPETVRLCIWQLV 111
Query 139 RSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVA-----YICSRF 193
++L Y H I HRDVKP+NLLV+ +T LKLCDFG A++L +S A Y+ +R+
Sbjct 112 KALSYCHRNDIVHRDVKPENLLVNLKTRKLKLCDFGFARQL---HESAAVPLTDYVATRW 168
Query 194 YRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGT--PTRC 251
YR+PEL+L EY +D+W++GC++GEL+ GRPLF G+ VDQL KI +LG P
Sbjct 169 YRSPELLLCDPEYGKPVDMWAVGCIMGELIDGRPLFPGDNEVDQLYKIQLVLGPLLPQHM 228
Query 252 QMSAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQ-AVDLMSKLLRYEPEQRLQ 310
+M N + FP++ P++ L F++ A+D +SKLL +P+ RL
Sbjct 229 EMFRQNSRFAGLAFPELPPRE--------TLLLRYRNKFDRTAIDFLSKLLCMDPKARLT 280
Query 311 PLEALAH 317
AL H
Sbjct 281 AKMALQH 287
> mmu:53886 Cdkl2, 5330436L21Rik, AI505225, KKIAMRE, Kkm, MGC144031,
MGC144032; cyclin-dependent kinase-like 2 (CDC2-related
kinase) (EC:2.7.11.22); K08824 cyclin-dependent kinase-like
[EC:2.7.11.22]
Length=568
Score = 171 bits (434), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 101/295 (34%), Positives = 169/295 (57%), Gaps = 28/295 (9%)
Query 23 KSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKN------RELEIMKALEHP 76
+ Y+ ++G GS+G+V + R ++G VAIKK L+ K RE++++K L H
Sbjct 2 EKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61
Query 77 NIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQ 136
N+V LL+ + + +V EFV T+ +K F + L + +++ Y +Q
Sbjct 62 NLVNLLEVCKKK--------KRWYLVFEFVDHTILDDLKLF----PNGLDYQVVQKYLFQ 109
Query 137 MCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLV-PGEQSVAYICSRFYR 195
+ +G+ H+ I HRD+KP+N+LV ++ V+KLCDFG A+ L PGE Y+ +R+YR
Sbjct 110 IINGIGFCHSHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGT--PTRCQM 253
APEL++G +Y A+DIW++GC++ E+L+G+PLF GE+ +DQL I+ LG P ++
Sbjct 169 APELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQEL 228
Query 254 SAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQR 308
NP + R P+VK + + + + + K E + L K L +P++R
Sbjct 229 FYKNPVFAGVRLPEVKDAEAEPLESRY------PKLPEAVISLAKKCLHIDPDKR 277
> ath:AT1G76540 CDKB2;1 (cyclin-dependent kinase B2;1); cyclin-dependent
protein kinase/ kinase/ protein binding; K00924
[EC:2.7.1.-]
Length=313
Score = 171 bits (433), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 100/295 (33%), Positives = 166/295 (56%), Gaps = 21/295 (7%)
Query 31 LGNGSFGVVTEARCLETGERVAIKK--VLQD----PRYKNRELEIMKAL-EHPNIVRLLD 83
+G G++G V AR TG+ VA+KK + +D P RE+ I++ L P++VRL+D
Sbjct 20 VGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDPHVVRLMD 79
Query 84 YFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGY 143
+E ++ L +V E++ V + ++SF +S+ +P IK YQ+C+ + +
Sbjct 80 VKQGLSKEGKTV---LYLVFEYMDTDVKKFIRSF-RSTGKNIPTQTIKSLMYQLCKGMAF 135
Query 144 LHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSRFYRAPELMLG 202
H GI HRD+KP NLL+D +T LK+ D G A+ +P ++ I + +YRAPE++LG
Sbjct 136 CHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYRAPEVLLG 195
Query 203 ANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQMSAMNPNYLE 262
A Y+TA+D+WS+GC+ EL+ + +F G++ + QL+ I ++ GTP ++
Sbjct 196 ATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPGVSTLKNW 255
Query 263 FRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
+P KP + + D E VDL+SK+L+YEP +R+ A+ H
Sbjct 256 HEYPQWKPSTLSSAVPNLD---------EAGVDLLSKMLQYEPAKRISAKMAMEH 301
> ath:AT1G73690 CDKD1;1 (CYCLIN-DEPENDENT KINASE D1;1); ATP binding
/ kinase/ protein kinase/ protein serine/threonine kinase;
K02202 cyclin-dependent kinase 7 [EC:2.7.11.22]
Length=398
Score = 170 bits (430), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 109/312 (34%), Positives = 168/312 (53%), Gaps = 36/312 (11%)
Query 18 MQQPQKSYD---MGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKN------RELE 68
M+QP+K D +VLG G++GVV +A + GE VAIKK+ + RE++
Sbjct 1 MEQPKKVADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIK 60
Query 69 IMKALEHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFI 128
++K L+HP+I+ L+D F + L++V EF+ ET +++ I+ L
Sbjct 61 LLKELKHPHIIELIDAFPHKEN--------LHIVFEFM-ETD---LEAVIRDRNLYLSPG 108
Query 129 LIKLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVA 187
+K Y + + L Y H + HRD+KP NLL+ LKL DFG A+ PG +
Sbjct 109 DVKSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGPNGQ-LKLADFGLARIFGSPGRKFTH 167
Query 188 YICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGT 247
+ +R+YRAPEL+ GA +Y A+D+W+ GC+ ELLL RP G + +DQL KI GT
Sbjct 168 QVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGT 227
Query 248 PTRCQMSAMN--PNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEP 305
P Q M P+Y+E++F V +++ + E A+DL+SK+ Y+P
Sbjct 228 PKADQWPDMICLPDYVEYQF--VPAPSLRSLLPT---------VSEDALDLLSKMFTYDP 276
Query 306 EQRLQPLEALAH 317
+ R+ +AL H
Sbjct 277 KSRISIQQALKH 288
> tpv:TP01_0678 serine/threonine protein kinase
Length=677
Score = 170 bits (430), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 94/317 (29%), Positives = 179/317 (56%), Gaps = 46/317 (14%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQ------DPRYKNRELEIMKALEH-PN 77
Y + Q +G G++G+V +A +T E VA+KK+ D + RE+ ++ L+ PN
Sbjct 15 YKIIQKIGKGAYGIVWKAVKRDTNEVVALKKIFDAFRNSTDAQRTYREIMFLQKLKKCPN 74
Query 78 IVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQM 137
IV+L D + + +R + +V E+V ++ V++S I H +IL YQ+
Sbjct 75 IVKLRDVYPADN------NRDVYLVFEYVETDLHAVIRSNILEEVHKR-YIL-----YQL 122
Query 138 CRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVA---------- 187
+++ ++H + HRD+KP N+L++ + ++ KL DFG A+ + P S+
Sbjct 123 LKAIHFIHTGDLLHRDLKPSNILLNNKCNI-KLADFGLARSVAPNNNSLDKCLSKDNTTG 181
Query 188 -----YICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKII 242
Y+ +R+YRAPE+++G+ +YT +D+W++GC+ E+LLGRP+F G ++++QL K+I
Sbjct 182 IVMTDYVATRWYRAPEILVGSTKYTKGVDMWAIGCIFAEMLLGRPMFPGSSTINQLAKVI 241
Query 243 QILGTPTRCQMSAMNPNYLEFRFPD--VKPKDWKAVFASHDCALGGDKSFEQAVDLMSKL 300
G P+ M +++ + + ++ K+ K F + + E+ +DL+++L
Sbjct 242 TFTGMPSEEDMDSLSSPFTKVMISSLTIRKKNIKEYFPN---------TCEEGLDLLNRL 292
Query 301 LRYEPEQRLQPLEALAH 317
L++ P +R+ ++ALAH
Sbjct 293 LQFNPTKRINTVDALAH 309
> cpv:cgd5_2510 Cdc2-like CDK2/CDC28 like protein kinase ; K04563
cyclin-dependent kinase [EC:2.7.11.22]
Length=295
Score = 169 bits (429), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 101/307 (32%), Positives = 170/307 (55%), Gaps = 38/307 (12%)
Query 23 KSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQD------PRYKNRELEIMKALEHP 76
+ Y + +G G++GVV +A+ G VA+K++ D P RE+ ++K L HP
Sbjct 3 EKYQKLEKVGEGTYGVVYKAKD-SQGRIVALKRIRLDAEDEGIPSTAIREISLLKELHHP 61
Query 77 NIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVM---KSFIKSSTHALPFILIKLY 133
NIV L+D ++E R L +V EF+ + + +V+ K+ ++ S IK+Y
Sbjct 62 NIVSLIDVIHSE--------RCLTLVFEFMEKDLKKVLDENKTGLQDSQ-------IKIY 106
Query 134 TYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRL-VPGEQSVAYICSR 192
YQ+ R + + H I HRD+KPQNLL++ LKL DFG A+ +P + +
Sbjct 107 LYQLLRGVAHCHQHRILHRDLKPQNLLIN-SDGALKLADFGLARAFGIPVRSYTHEVVTL 165
Query 193 FYRAPELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTRCQ 252
+YRAP++++G+ +Y+T++DIWS+GC+ E++ G+PLF G T DQL KI ILGTP +
Sbjct 166 WYRAPDVLMGSKKYSTSVDIWSIGCIFAEMITGKPLFPGVTDDDQLPKIFSILGTPNPRE 225
Query 253 MSAMN--PNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQ 310
+ P + + F + K W ++ C ++ +DL+S +L ++P +R+
Sbjct 226 WPQVQELPLWKQRTFQVFEKKPWSSIIPGF-C--------QEGIDLLSNMLCFDPNKRIS 276
Query 311 PLEALAH 317
+A+ H
Sbjct 277 ARDAMNH 283
> hsa:5595 MAPK3, ERK1, HS44KDAP, HUMKER1A, MGC20180, P44ERK1,
P44MAPK, PRKM3; mitogen-activated protein kinase 3 (EC:2.7.11.24);
K04371 extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
Length=357
Score = 169 bits (429), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 105/306 (34%), Positives = 165/306 (53%), Gaps = 33/306 (10%)
Query 25 YDMGQVLGNGSFGVVTEARCLETGERVAIKKV--LQDPRYKNR---ELEIMKALEHPNIV 79
Y Q +G G++G+V+ A RVAIKK+ + Y R E++I+ H N++
Sbjct 42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVI 101
Query 80 RLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQMCR 139
+ D E R + +V + + +Y+++KS S+ H F+ YQ+ R
Sbjct 102 GIRDILRASTLE---AMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFL------YQILR 152
Query 140 SLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLVPGEQSVA----YICSRFYR 195
L Y+H+ + HRD+KP NLL++ T LK+CDFG A+ P Y+ +R+YR
Sbjct 153 GLKYIHSANVLHRDLKPSNLLIN-TTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYR 211
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGTPTR----C 251
APE+ML + YT +IDIWS+GC+L E+L RP+F G+ +DQL I+ ILG+P++ C
Sbjct 212 APEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNC 271
Query 252 QMSAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQP 311
++ NYL+ P W +F KS +A+DL+ ++L + P +R+
Sbjct 272 IINMKARNYLQ-SLPSKTKVAWAKLFP---------KSDSKALDLLDRMLTFNPNKRITV 321
Query 312 LEALAH 317
EALAH
Sbjct 322 EEALAH 327
> dre:360144 mapk1, zERK2; mitogen-activated protein kinase 1
(EC:2.7.11.24); K04371 extracellular signal-regulated kinase
1/2 [EC:2.7.11.24]
Length=369
Score = 169 bits (429), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 109/337 (32%), Positives = 182/337 (54%), Gaps = 40/337 (11%)
Query 1 TFSSSSSSKGNRRSASGMQQPQ-KSYDMG------QVLGNGSFGVVTEARCLETGERVAI 53
T + S+ + G SG + + +++D+G +G G++G+V A + RVAI
Sbjct 3 TAAVSAPAGGGPNPGSGAEMVRGQAFDVGPRYSNLSYIGGGAYGMVCSAYDRDNKVRVAI 62
Query 54 KKV--LQDPRYKNR---ELEIMKALEHPNIVRLLDYFYTEVEERGSISRFLNVVMEFVPE 108
KK+ + Y R E++I+ +H NI+ + D T ++ + + +V + +
Sbjct 63 KKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRTPTIDQ---MKDVYIVQDLMET 119
Query 109 TVYRVMKSFIKSSTHALPFILIKLYTYQMCRSLGYLHALGICHRDVKPQNLLVDYRTHVL 168
+Y+++K+ S+ H F+ YQ+ R L Y+H+ + HRD+KP NLL++ T L
Sbjct 120 DLYKLLKTQHLSNDHICYFL------YQILRGLKYIHSANVLHRDLKPSNLLLN-TTCDL 172
Query 169 KLCDFGSAKRLVPGEQSVA----YICSRFYRAPELMLGANEYTTAIDIWSLGCVLGELLL 224
K+CDFG A+ P Y+ +R+YRAPE+ML + YT +IDIWS+GC+L E+L
Sbjct 173 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS 232
Query 225 GRPLFAGETSVDQLVKIIQILGTPTR----CQMSAMNPNYLEFRFPDVKPKDWKAVFASH 280
RP+F G+ +DQL I+ ILG+P++ C ++ NYL P W +F +
Sbjct 233 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINIKARNYL-LSLPLRSKVPWNRLFPNA 291
Query 281 DCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLEALAH 317
D +A+DL+ K+L + P +R++ EALAH
Sbjct 292 D---------PKALDLLDKMLTFNPHKRIEVEEALAH 319
> hsa:8999 CDKL2, KKIAMRE, P56; cyclin-dependent kinase-like 2
(CDC2-related kinase) (EC:2.7.11.22); K08824 cyclin-dependent
kinase-like [EC:2.7.11.22]
Length=493
Score = 169 bits (428), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 102/304 (33%), Positives = 167/304 (54%), Gaps = 30/304 (9%)
Query 23 KSYDMGQVLGNGSFGVVTEARCLETGERVAIKKVLQDPRYKN------RELEIMKALEHP 76
+ Y+ ++G GS+G+V + R +TG VAIKK L+ K RE++++K L H
Sbjct 2 EKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHE 61
Query 77 NIVRLLDYFYTEVEERGSISRFLNVVMEFVPETVYRVMKSFIKSSTHALPFILIKLYTYQ 136
N+V LL E + +V EFV T+ ++ F + L + +++ Y +Q
Sbjct 62 NLVNLL--------EVCKKKKRWYLVFEFVDHTILDDLELF----PNGLDYQVVQKYLFQ 109
Query 137 MCRSLGYLHALGICHRDVKPQNLLVDYRTHVLKLCDFGSAKRLV-PGEQSVAYICSRFYR 195
+ +G+ H+ I HRD+KP+N+LV ++ V+KLCDFG A+ L PGE Y+ +R+YR
Sbjct 110 IINGIGFCHSHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168
Query 196 APELMLGANEYTTAIDIWSLGCVLGELLLGRPLFAGETSVDQLVKIIQILGT--PTRCQM 253
APEL++G +Y A+D+W++GC++ E+ +G PLF G++ +DQL I+ LG P ++
Sbjct 169 APELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQEL 228
Query 254 SAMNPNYLEFRFPDVKPKDWKAVFASHDCALGGDKSFEQAVDLMSKLLRYEPEQRLQPLE 313
NP + R P++K ++ K E +DL K L +P++R E
Sbjct 229 FNKNPVFAGVRLPEIKERE--------PLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAE 280
Query 314 ALAH 317
L H
Sbjct 281 LLHH 284
Lambda K H
0.323 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 16716174816
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40