bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0839_orf2
Length=185
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7)... 209 6e-54
bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9); ... 206 4e-53
cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin red... 201 1e-51
tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thior... 196 3e-50
pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thiore... 195 7e-50
cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-... 164 1e-40
hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thior... 164 2e-40
xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1... 163 3e-40
mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:... 162 5e-40
xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1... 159 5e-39
mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase 3... 157 2e-38
mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd... 155 6e-38
hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin r... 155 8e-38
dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredo... 153 3e-37
xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1... 153 4e-37
cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr... 150 2e-36
pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 gluta... 118 1e-26
tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7) 117 3e-26
xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7); ... 114 2e-25
mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione re... 113 3e-25
hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7); K0... 112 7e-25
sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathio... 110 3e-24
eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreducta... 108 1e-23
tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7)... 95.5 9e-20
ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding / gl... 94.7 2e-19
hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3 (E... 92.4 7e-19
cel:C46F11.2 hypothetical protein 90.9 2e-18
dre:100332932 glutathione reductase-like 84.0 2e-16
ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase); ... 77.8 2e-14
dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathi... 73.6 4e-13
hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehy... 50.4 4e-06
mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogen... 50.1 4e-06
xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1... 45.8 9e-05
cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehyd... 45.4 1e-04
sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the li... 45.4 1e-04
dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase (E... 45.1 2e-04
ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoa... 43.1 6e-04
ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrol... 41.6 0.001
ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrog... 41.2 0.002
ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP ... 40.8 0.003
tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.... 40.8 0.003
sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogena... 40.4 0.003
tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putativ... 39.7 0.005
eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydroge... 38.5 0.012
eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotid... 36.2 0.066
tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00... 35.8 0.097
pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4); ... 33.1 0.50
cel:F52G3.4 hypothetical protein 31.2 2.1
dre:100151626 tatdn1, MGC191238, MGC92362, zgc:92362; TatD DNa... 30.0 4.4
pfa:PF08_0048 ATP-dependent helicase, putative; K01509 adenosi... 30.0 4.6
> tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=662
Score = 209 bits (531), Expect = 6e-54, Method: Compositional matrix adjust.
Identities = 103/176 (58%), Positives = 127/176 (72%), Gaps = 7/176 (3%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AGE+LARRLF N TE ++PTTVFTP+EY G SEE A A++G ++LE
Sbjct 485 ELTPVAIKAGEILARRLFANSTEHMDFTNIPTTVFTPIEYAHTGYSEEAAEAEFGRDDLE 544
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VYL +FSPL S HR+K Q A ED ++P CLAKLIC++ + ++VVGIH
Sbjct 545 VYLFQFSPLFFSCVHREKAPQ-------ARKSPEDVDITPPCLAKLICVKSEDEKVVGIH 597
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAA 176
FVGP AGE++QG ALA+RLGA K DFD VGIHPTNAE FM L +TK SGE +VA+
Sbjct 598 FVGPNAGELMQGFALAVRLGAKKRDFDKCVGIHPTNAEAFMALTVTKASGEPFVAS 653
> bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=559
Score = 206 bits (524), Expect = 4e-53, Method: Compositional matrix adjust.
Identities = 95/184 (51%), Positives = 131/184 (71%), Gaps = 11/184 (5%)
Query 2 LTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLEV 61
L A++ GE+LARRLF N ++ L +VP VFTP+EYG GLSEE+A+ KYG+ +++
Sbjct 387 LATVAVKDGEMLARRLFGNSNKLMDLNYVPMCVFTPIEYGKCGLSEEEAVKKYGD--VDI 444
Query 62 YLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHF 121
YL+EF+ LE SA HR K++ + ++ D + P CL+K+IC K +VGIHF
Sbjct 445 YLKEFTSLEFSAVHRHKVEW-------MQTDEMDVDMPPTCLSKMIC--KKDGTIVGIHF 495
Query 122 VGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCGG 181
VGP AGE++QG+ +A+RLGA K DFD T+G+HPT+AE FM L +TK SGE+WV + GCGG
Sbjct 496 VGPNAGEIIQGLCVAVRLGAKKSDFDDTIGVHPTDAESFMNLTVTKASGESWVQSAGCGG 555
Query 182 GKCG 185
G+CG
Sbjct 556 GRCG 559
> cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=526
Score = 201 bits (511), Expect = 1e-51, Method: Compositional matrix adjust.
Identities = 97/176 (55%), Positives = 128/176 (72%), Gaps = 7/176 (3%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP A++AG LLARRLF E + VPTTVFTP+EYG VGLS E AIAKYGE+++E
Sbjct 349 ELTPVAVKAGILLARRLFAGSNEFIDYDFVPTTVFTPIEYGHVGLSSEAAIAKYGEDDIE 408
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
YL EFS LE++A HR+K + E + D +L CLAKL+ ++ ++VVG H
Sbjct 409 EYLSEFSTLEIAAAHREKPEHLRENEM-------DFALPLNCLAKLVVVKSQGEKVVGFH 461
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAA 176
FVGP AGE+ QG +LA++LGATK+DFD +GIHPT+AE F L++TKRSGE++V++
Sbjct 462 FVGPNAGEITQGFSLAVKLGATKKDFDDMIGIHPTDAEVFGILEVTKRSGESFVSS 517
> tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=567
Score = 196 bits (499), Expect = 3e-50, Method: Composition-based stats.
Identities = 93/185 (50%), Positives = 122/185 (65%), Gaps = 13/185 (7%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
+L P AI++ ELL +RL+ N E+VP V+TP EY GL+EE+AI ++GEENLE
Sbjct 396 KLAPVAIKSSELLIQRLYSNTNTKMNYENVPKCVYTPFEYSSCGLTEEEAIERFGEENLE 455
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
+YL+E++ LE+S HR K DE D CL+K+ICLR K +VG+H
Sbjct 456 IYLKEYNNLEISPVHRINKKTNDEFD-----------YPMTCLSKVICLRDGK--IVGMH 502
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
FVGP AGE++QG ++ L A K D D TVGIHPT+AE F+ L +TK SG++WVA GGC
Sbjct 503 FVGPNAGEIMQGFSVLFTLNAKKSDLDKTVGIHPTDAESFVNLTVTKASGDSWVATGGCA 562
Query 181 GGKCG 185
GGKCG
Sbjct 563 GGKCG 567
> pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=617
Score = 195 bits (496), Expect = 7e-50, Method: Composition-based stats.
Identities = 90/170 (52%), Positives = 122/170 (71%), Gaps = 7/170 (4%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
EL P AI+AGE+LARRLFK+ E+ ++PT+++TP+EYG G SEE A YG+ N+E
Sbjct 440 ELAPVAIKAGEILARRLFKDSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVE 499
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
V+L+EF+ LE+SA HRQK + A+ ++ D +S CLAKL+CL+ + RV+G H
Sbjct 500 VFLQEFNNLEISAVHRQKHIR-------AQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFH 552
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSG 170
+VGP AGEV QGMALA+RL K+DFD+ +GIHPT+AE FM L +T SG
Sbjct 553 YVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESFMNLFVTISSG 602
> cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-1);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=667
Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 82/181 (45%), Positives = 111/181 (61%), Gaps = 20/181 (11%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG +L RR+F E+ + +PTTVFTP+EYGC GLSEEDA+ KYG++N+
Sbjct 507 ELTPVAIQAGRVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNII 566
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
+Y F+PLE + R D+D C K+ICLR ++++VVG H
Sbjct 567 IYHNVFNPLEYTISERM-------------DKDH-------CYLKMICLRNEEEKVVGFH 606
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
+ P AGEV QG +A++L A K DFD +GIHPT AE F L + K+ G+ + A GC
Sbjct 607 ILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAENFTTLTLEKKEGDEELQASGCU 666
Query 181 G 181
G
Sbjct 667 G 667
> hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=649
Score = 164 bits (415), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 92/181 (50%), Positives = 111/181 (61%), Gaps = 22/181 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG LLA+RL+ T E+VPTTVFTP+EYG GLSEE A+ K+GEEN+E
Sbjct 491 ELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIE 550
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + I RD C AK+IC KD +RVVG H
Sbjct 551 VYHSYFWPLEWT------IPSRDNNK---------------CYAKIICNTKDNERVVGFH 589
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
+GP AGEV QG A A++ G TK+ DST+GIHP AE F L +TKRSG + + A GC
Sbjct 590 VLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQA-GCU 648
Query 181 G 181
G
Sbjct 649 G 649
> xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=531
Score = 163 bits (412), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 87/177 (49%), Positives = 109/177 (61%), Gaps = 21/177 (11%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG LLA+RL+ + T +VPTTVFTP+EYG GLSEE+AI +YGEEN+E
Sbjct 375 ELTPVAIQAGRLLAKRLYGDSTLKSDYVNVPTTVFTPLEYGACGLSEENAIRQYGEENVE 434
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + R K C AK+IC KD +RVVG H
Sbjct 435 VYHSYFWPLEWTVPARDNNK---------------------CYAKIICNLKDNERVVGFH 473
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAG 177
+ P AGE+ QG A+AI+ G TK+ D+T+GIHP AE F L +TKRSG N + +G
Sbjct 474 VLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEIFTTLTVTKRSGGNILQSG 530
> mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=499
Score = 162 bits (410), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 89/181 (49%), Positives = 109/181 (60%), Gaps = 22/181 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG LLA+RL+ ++VPTTVFTP+EYGC GLSEE A+ K+GEEN+E
Sbjct 341 ELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIE 400
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + R K C AK+IC KD +RVVG H
Sbjct 401 VYHSFFWPLEWTVPSRDNNK---------------------CYAKIICNLKDDERVVGFH 439
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
+GP AGEV QG A A++ G TK+ DST+GIHP AE F L +TKRSG + + GC
Sbjct 440 VLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGD-ILQSGCU 498
Query 181 G 181
G
Sbjct 499 G 499
> xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=504
Score = 159 bits (402), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 84/170 (49%), Positives = 106/170 (62%), Gaps = 21/170 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI AG+LLA RLF E+ + VPTTVFTP+EYGCVG+SEE+A +YG++N+E
Sbjct 346 ELTPTAIAAGKLLAIRLFSGSAELMDYDSVPTTVFTPLEYGCVGISEEEAKERYGDDNIE 405
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
V+ + PLE + + +RD C K+ICLRK QR++G+H
Sbjct 406 VFHAFYKPLEFT------VAERDASQ---------------CYIKIICLRKHDQRILGLH 444
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSG 170
GP AGEV+QG AL I+ GAT TVGIHPT AE +L ITKRSG
Sbjct 445 LTGPNAGEVIQGFALGIKCGATYPQLMCTVGIHPTCAEEVTKLHITKRSG 494
> mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase
3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=652
Score = 157 bits (396), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 89/181 (49%), Positives = 109/181 (60%), Gaps = 22/181 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG+LLARRLF E ++PTTVFTP+EYGC GLSEE AI Y +ENLE
Sbjct 494 ELTPVAIQAGKLLARRLFGVSLEKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLE 553
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + R D +T C AK+IC + D +RVVG H
Sbjct 554 VYHTLFWPLEWTVAGR----------------DNNT-----CYAKIICNKFDNERVVGFH 592
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
+GP AGE+ QG A A++ G TK+ D T+GIHPT E F L+ITK SG + + GC
Sbjct 593 LLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD-ITQKGCU 651
Query 181 G 181
G
Sbjct 652 G 652
> mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2;
thioredoxin reductase 2 (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=527
Score = 155 bits (393), Expect = 6e-38, Method: Compositional matrix adjust.
Identities = 81/170 (47%), Positives = 109/170 (64%), Gaps = 21/170 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG+LLA+RLF + + +VPTTVFTP+EYGCVGLSEE+A+A +G+E++E
Sbjct 369 ELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVE 428
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY + PLE + D D S C K++C+R+ Q V+G+H
Sbjct 429 VYHAYYKPLEFTVA------------------DRDASQ---CYIKMVCMREPPQLVLGLH 467
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSG 170
F+GP AGEV QG AL I+ GA+ TVGIHPT +E ++L I+KRSG
Sbjct 468 FLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSG 517
> hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin
reductase 2 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH)
[EC:1.8.1.9]
Length=524
Score = 155 bits (392), Expect = 8e-38, Method: Compositional matrix adjust.
Identities = 82/181 (45%), Positives = 113/181 (62%), Gaps = 22/181 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI AG LL +RLF +++ ++VPTTVFTP+EYGCVGLSEE+A+A++G+E++E
Sbjct 366 ELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVE 425
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY + PLE + R + C K++CLR+ Q V+G+H
Sbjct 426 VYHAHYKPLEFTVAGRDASQ---------------------CYVKMVCLREPPQLVLGLH 464
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
F+GP AGEV QG AL I+ GA+ TVGIHPT +E ++L+I+KRSG + GC
Sbjct 465 FLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLD-PTVTGCU 523
Query 181 G 181
G
Sbjct 524 G 524
> dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=602
Score = 153 bits (387), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 84/181 (46%), Positives = 106/181 (58%), Gaps = 22/181 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG+LLARRL+ T +VPTTVFTP+EYG G EE AI YG+ENLE
Sbjct 444 ELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLE 503
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + R K C AK+IC + D RV+G H
Sbjct 504 VYHSLFWPLEFTVPGRDNNK---------------------CYAKIICNKLDNLRVIGFH 542
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
++GP AGEV QG A++ G TK+ D+T+GIHPT AE F +++TK SG + + GC
Sbjct 543 YLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGD-ITQSGCU 601
Query 181 G 181
G
Sbjct 602 G 602
> xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=596
Score = 153 bits (386), Expect = 4e-37, Method: Compositional matrix adjust.
Identities = 84/179 (46%), Positives = 106/179 (59%), Gaps = 22/179 (12%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI+AG LLARRL++ +VPTTVFTP+EYGC G +EE AI YGEENLE
Sbjct 440 ELTPVAIQAGRLLARRLYRGSKVKCDYINVPTTVFTPLEYGCCGYAEEKAIEIYGEENLE 499
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PLE + R D +T C AK+IC ++D RV+G H
Sbjct 500 VYHTLFWPLEWTVPSR----------------DNNT-----CFAKIICNKQDNDRVIGFH 538
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGC 179
+GP AGE+ QG A++ G TKE D T+GIHPT AE F + +K SG + ++ GC
Sbjct 539 VLGPNAGEITQGFGAAMKCGLTKEKLDETIGIHPTCAEIFTTMDTSKSSGGD-ISQKGC 596
> cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr-2);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=503
Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 75/180 (41%), Positives = 112/180 (62%), Gaps = 20/180 (11%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI++G+LLA RLF N ++ + V TTVFTP+E VGL+EE+AI K+GE+++E
Sbjct 344 ELTPLAIQSGKLLADRLFSNSKQIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIE 403
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
V+ F+P E +++D+ C K +C R + Q+++G+H
Sbjct 404 VFHSHFTPFEYVV-----------------PQNKDSGF---CYVKAVCTRDESQKILGLH 443
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
FVGP A EV+QG A+A R+G + D +T+ IHP ++E F++L ITKRSG++ G CG
Sbjct 444 FVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHPCSSEEFVKLHITKRSGQDPRTQGCCG 503
> pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=500
Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 65/164 (39%), Positives = 94/164 (57%), Gaps = 19/164 (11%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
+LTP AI AG LLA RLF +T + +PT +F+ G +GLSEE AI YG+EN++
Sbjct 352 QLTPVAINAGRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVK 411
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
+Y +F+ L S D + L KL+C+ KD + + G+H
Sbjct 412 IYESKFTNLFFSVY------------------DIEPELKEKTYLKLVCVGKD-ELIKGLH 452
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
+G A E++QG A+A+++ ATK+DFD T+ IHPT AE F+ LQ
Sbjct 453 IIGLNADEIVQGFAVALKMNATKKDFDETIPIHPTAAEEFLTLQ 496
> tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7)
Length=505
Score = 117 bits (292), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 69/173 (39%), Positives = 93/173 (53%), Gaps = 23/173 (13%)
Query 2 LTPAAIRAGELLARRLFKNQTEV-FCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
L P A+ AG LLA RLF ++E L VPT VF+ G VG++EEDA + YGEEN+
Sbjct 333 LAPVAVAAGRLLADRLFGGRSEARLDLSVVPTVVFSHPALGAVGMTEEDAKSLYGEENIN 392
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F +A S P K++CL+ +V+G+H
Sbjct 393 VYTSTFIDSFYAAWSMPP------------------SAKPKSFVKMVCLKTANDKVLGLH 434
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQL----QITKRS 169
VG E+LQG A+AI+LGATK DF+ST+ IHPT AE + L +T+R+
Sbjct 435 LVGRNVDEMLQGFAVAIKLGATKADFNSTLAIHPTAAEEVVTLPHPKPVTRRA 487
> xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=476
Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 66/164 (40%), Positives = 96/164 (58%), Gaps = 24/164 (14%)
Query 2 LTPAAIRAGELLARRLFKNQTEV-FCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP AI AG L+ RLF+ Q + ++PT VF+ G VGL+EE+A+ G EN++
Sbjct 336 LTPVAIAAGRKLSHRLFEGQEDSKLDYNNIPTVVFSHPPIGTVGLTEEEAVTAKGRENVK 395
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY FSP+ R+K K C+ KL+C+ K+ ++VVG+H
Sbjct 396 VYTTSFSPM-YHVVTRRKTK---------------------CVMKLVCVGKE-EKVVGLH 432
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
G E+LQG A+AI++GATK+DFD+TV IHPT++E + L+
Sbjct 433 MQGLGCDEMLQGFAVAIKMGATKKDFDNTVAIHPTSSEELVTLR 476
> mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione
reductase (EC:1.8.1.7); K00383 glutathione reductase (NADPH)
[EC:1.8.1.7]
Length=500
Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 64/164 (39%), Positives = 97/164 (59%), Gaps = 24/164 (14%)
Query 2 LTPAAIRAGELLARRLFK-NQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP AI AG LA RLF+ Q +++PT VF+ G VGL+E++A+ KYG++N++
Sbjct 360 LTPVAIAAGRKLAHRLFECKQDSKLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVK 419
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
+Y F+P+ A +K K C+ K++C K+ ++VVGIH
Sbjct 420 IYSTAFTPM-YHAVTTRKTK---------------------CVMKMVCANKE-EKVVGIH 456
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
G E+LQG A+A+++GATK DFD+TV IHPT++E + L+
Sbjct 457 MQGIGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 500
> hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=522
Score = 112 bits (280), Expect = 7e-25, Method: Compositional matrix adjust.
Identities = 65/164 (39%), Positives = 96/164 (58%), Gaps = 24/164 (14%)
Query 2 LTPAAIRAGELLARRLFKNQTEV-FCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP AI AG LA RLF+ + + ++PT VF+ G VGL+E++AI KYG EN++
Sbjct 382 LTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVK 441
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
Y F+P+ A ++K K C+ K++C K+ ++VVGIH
Sbjct 442 TYSTSFTPM-YHAVTKRKTK---------------------CVMKMVCANKE-EKVVGIH 478
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
G E+LQG A+A+++GATK DFD+TV IHPT++E + L+
Sbjct 479 MQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 522
> sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathione
oxidoreductase, converts oxidized glutathione to reduced
glutathione; mitochondrial but not cytosolic form has a role
in resistance to hyperoxia (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 62/167 (37%), Positives = 97/167 (58%), Gaps = 26/167 (15%)
Query 1 ELTPAAIRAGELLARRLF---KNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEE 57
ELTP AI AG L+ RLF K + + E+VP+ +F+ E G +G+SE++AI KYG+E
Sbjct 340 ELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKE 399
Query 58 NLEVYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVV 117
N++VY +F+ + + + SP K++C + ++VV
Sbjct 400 NIKVYNSKFTAMYYAMLSEK---------------------SPTRY-KIVCAGPN-EKVV 436
Query 118 GIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
G+H VG + E+LQG +AI++GATK DFD+ V IHPT+AE + ++
Sbjct 437 GLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483
> eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreductase
(EC:1.8.1.7); K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=450
Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 63/166 (37%), Positives = 96/166 (57%), Gaps = 26/166 (15%)
Query 1 ELTPAAIRAGELLARRLFKNQT-EVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENL 59
ELTP A+ AG L+ RLF N+ E ++PT VF+ G VGL+E A +YG++ +
Sbjct 309 ELTPVAVAAGRRLSERLFNNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQV 368
Query 60 EVYLREFSPLEVSAC-HRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVG 118
+VY F+ + + HRQ PC + KL+C+ + +++VG
Sbjct 369 KVYKSSFTAMYTAVTTHRQ----------------------PCRM-KLVCVGSE-EKIVG 404
Query 119 IHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
IH +G E+LQG A+A+++GATK+DFD+TV IHPT AE F+ ++
Sbjct 405 IHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR 450
> tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 62/167 (37%), Positives = 89/167 (53%), Gaps = 29/167 (17%)
Query 1 ELTPAAIRAGELLARRLF----KNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGE 56
ELTP AI AG LA RLF + + C VPT VF+ CVGL+E +A A YGE
Sbjct 332 ELTPVAIAAGRRLADRLFGGLCNAKLDSAC---VPTVVFSHPPAACVGLTEAEAKATYGE 388
Query 57 ENLEVYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRV 116
++++V++ + A E+K P K+IC++ +V
Sbjct 389 KDIKVHVNLYYGAWPVA----------PEEK------------PKTFIKMICVKSQMLKV 426
Query 117 VGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQL 163
VG+H VG A E++QG +A+++GATK DFD+ V +HPT AE + L
Sbjct 427 VGLHVVGMGADEMIQGFGVAMKMGATKADFDNCVAVHPTAAEEVVTL 473
> ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding /
glutathione-disulfide reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=565
Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 25/168 (14%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP A+ G LA+ LF+N+ VP VF+ G VGL+EE AI +YG+ ++
Sbjct 402 NLTPVALMEGGALAKTLFQNEPTKPDYRAVPCAVFSQPPIGTVGLTEEQAIEQYGD--VD 459
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY F PL+ + G D + ++C +K V+G+H
Sbjct 460 VYTSNFRPLKATLS-------------GLPDR--------VFMKLIVCANTNK--VLGVH 496
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKR 168
G ++ E++QG +A++ G TK DFD+TVG+HPT AE F+ ++ R
Sbjct 497 MCGEDSPEIIQGFGVAVKAGLTKADFDATVGVHPTAAEEFVTMRAPTR 544
> hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3
(EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=607
Score = 92.4 bits (228), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 63/181 (34%), Positives = 82/181 (45%), Gaps = 58/181 (32%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
ELTP AI++G+LLA+RLF LE + T+F P+E+ G EN
Sbjct 485 ELTPVAIQSGKLLAQRLFGAS-----LEKIYHTLFWPLEWTVA-----------GREN-- 526
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
C AK+IC + D RV+G H
Sbjct 527 ---------------------------------------NTCYAKIICNKFDHDRVIGFH 547
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRSGENWVAAGGCG 180
+GP AGEV QG A A++ G TK+ D T+GIHPT E F L+ITK SG + + GC
Sbjct 548 ILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD-ITQKGCU 606
Query 181 G 181
G
Sbjct 607 G 607
> cel:C46F11.2 hypothetical protein
Length=473
Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 60/165 (36%), Positives = 93/165 (56%), Gaps = 26/165 (15%)
Query 2 LTPAAIRAGELLARRLFKNQTE-VFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP AI AG L+ RLF +T+ E++ T VF+ G VGL+E +A+ KYG++ +
Sbjct 327 LTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVT 386
Query 61 VYLREFSPLEVSAC-HRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGI 119
+Y F+P+ + H++K KL+C+ KD ++VVG+
Sbjct 387 LYKSRFNPMLFAVTKHKEK-----------------------AAMKLVCVGKD-EKVVGV 422
Query 120 HFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
H G + E+LQG A+A+ +GATK+ FD TV IHPT+AE + ++
Sbjct 423 HVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTMR 467
> dre:100332932 glutathione reductase-like
Length=461
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 55/163 (33%), Positives = 81/163 (49%), Gaps = 25/163 (15%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
+LTP AI ++K+ + + T VF+ E G VGLSEE A +Y E +E
Sbjct 311 QLTPVAIHEAMCFIETVYKDNPTKPDHDLIATAVFSQPEIGTVGLSEETAAERYAE--IE 368
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
VY EF P++ + RQ+ L KLI D+ +VVG H
Sbjct 369 VYRAEFRPMKATLSGRQE----------------------KMLMKLIVNAADR-KVVGAH 405
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQL 163
+G +AGE+ Q + + ++ G TKEDFD T+ +HPT AE + +
Sbjct 406 ILGHDAGEMAQLLGITLKAGCTKEDFDRTMAVHPTAAEELVTM 448
> ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase);
FAD binding / NADP or NADPH binding / glutathione-disulfide
reductase/ oxidoreductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=499
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 54/169 (31%), Positives = 84/169 (49%), Gaps = 25/169 (14%)
Query 1 ELTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLE 60
LTP A+ A F + +V VF VGLSEE+A+ + ++
Sbjct 344 NLTPVALMEATCFANTAFGGKPTKAEYSNVACAVFCIPPLAVVGLSEEEAVEQ-ATGDIL 402
Query 61 VYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIH 120
V+ F+P++ + RQ+ L KLI K +V+G
Sbjct 403 VFTSGFNPMKNTISGRQE----------------------KTLMKLIVDEKS-DKVIGAS 439
Query 121 FVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ-ITKR 168
GP+A E++QG+A+A++ GATK FDSTVGIHP++AE F+ ++ +T+R
Sbjct 440 MCGPDAAEIMQGIAIALKCGATKAQFDSTVGIHPSSAEEFVTMRSVTRR 488
> dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=425
Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 38/120 (31%), Positives = 66/120 (55%), Gaps = 23/120 (19%)
Query 45 LSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLA 104
L+ ++A+ YG++ ++VY F+P+ + R+ C+
Sbjct 329 LTPDEAVKTYGKDKVKVYTTSFTPMYYAITSRKS----------------------QCIM 366
Query 105 KLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQ 164
KL+C ++ ++VVG+H G E+LQG A+A+ +GATK DFD T+ IHPT++E + L+
Sbjct 367 KLVCAGEN-EKVVGLHMQGFGCDEMLQGFAVAVNMGATKADFDRTIAIHPTSSEELVTLR 425
> hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=509
Score = 50.4 bits (119), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 42/143 (29%), Positives = 64/143 (44%), Gaps = 25/143 (17%)
Query 30 VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGA 89
VP+ ++T E VG SEE + EE +E + +F +A R K
Sbjct 389 VPSVIYTHPEVAWVGKSEE----QLKEEGIEYKVGKFP---FAANSRAK----------- 430
Query 90 EDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDST 149
+ D D + I +K RV+G H +GP AGE++ ALA+ GA+ ED
Sbjct 431 TNADTDGMVK-------ILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARV 483
Query 150 VGIHPTNAECFMQLQITKRSGEN 172
HPT +E F + + G++
Sbjct 484 CHAHPTLSEAFREANLAASFGKS 506
> mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 42/142 (29%), Positives = 62/142 (43%), Gaps = 25/142 (17%)
Query 30 VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGA 89
VP+ ++T E VG SEE + EE +E + +F +A R K
Sbjct 389 VPSVIYTHPEVAWVGKSEE----QLKEEGIEFKIGKFP---FAANSRAK----------- 430
Query 90 EDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDST 149
+ D D + I K RV+G H +GP AGE++ ALA+ GA+ ED
Sbjct 431 TNADTDGMVK-------ILGHKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARV 483
Query 150 VGIHPTNAECFMQLQITKRSGE 171
HPT +E F + + G+
Sbjct 484 CHAHPTLSEAFREANLAAAFGK 505
> xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 45.8 bits (107), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 25/142 (17%)
Query 30 VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGA 89
VP+ ++T E VG SEE + EE E + +F P +A R K
Sbjct 389 VPSVIYTHPEVAWVGKSEE----QLKEEGTEYKVGKF-PF--AANSRAK----------- 430
Query 90 EDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDST 149
+ D D L K++ K R++G H +G AGE++ ALA+ GA+ ED
Sbjct 431 TNADTDG------LVKILS-HKTTDRMLGAHILGASAGEMINEAALAMEYGASCEDVARV 483
Query 150 VGIHPTNAECFMQLQITKRSGE 171
HPT +E F + + G+
Sbjct 484 CHAHPTVSEAFREANLAASFGK 505
> cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=495
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query 112 DKQ--RVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQITKRS 169
DKQ R++G+H +GP AGE++ LA+ GA+ ED HPT +E F + +
Sbjct 429 DKQTDRMLGVHIIGPNAGEMIAEATLAMEYGASAEDVARVCHPHPTLSEAFREANLAAYC 488
Query 170 GE 171
G+
Sbjct 489 GK 490
> sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the
lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase
and 2-oxoglutarate dehydrogenase multi-enzyme complexes
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 0/59 (0%)
Query 107 ICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQLQI 165
I + +R++G H +GP AGE++ LA+ GA+ ED HPT +E F + +
Sbjct 432 ILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANM 490
> dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 25/142 (17%)
Query 30 VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGA 89
VP+ ++T E VG +EE + EE + + +F +A R K
Sbjct 387 VPSVIYTHPEVAWVGKTEE----QLKEEGVPYKVGKFP---FAANSRAK----------- 428
Query 90 EDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDST 149
+ D D L K++ KD R++G H +G AGE++ ALA+ GA+ ED
Sbjct 429 TNADTDG------LVKILS-HKDTDRMLGAHILGSGAGEMINEAALAMEYGASCEDVARV 481
Query 150 VGIHPTNAECFMQLQITKRSGE 171
HPT +E F + + G+
Sbjct 482 CHAHPTVSEAFREANLAASFGK 503
> ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=630
Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 40/140 (28%), Positives = 58/140 (41%), Gaps = 23/140 (16%)
Query 26 CLEH--VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRD 83
L H +P FT E VGL+E A K +E +V + K +
Sbjct 491 VLNHLSIPAACFTHPEISMVGLTEPQAREKAEKEGFKVSI-------------AKTSFKA 537
Query 84 EEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATK 143
AE+E E LAK+I R D ++G+H G A +++ + AI LG
Sbjct 538 NTKALAENEGEG-------LAKMI-YRPDNGEILGVHIFGLHAADLIHEASNAIALGTRI 589
Query 144 EDFDSTVGIHPTNAECFMQL 163
+D V HPT +E +L
Sbjct 590 QDIKLAVHAHPTLSEVVDEL 609
> ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrolipoyl
dehydrogenase; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=623
Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 23/140 (16%)
Query 26 CLEH--VPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRD 83
L H +P FT E VGL+E A K +E +V + V + K
Sbjct 431 VLNHLSIPAACFTHPEISMVGLTEPQAKEKGEKEGFKVSV-------VKTSFKANTKAL- 482
Query 84 EEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATK 143
AE+E E +AK+I R D ++G+H G A +++ + AI LG
Sbjct 483 -----AENEGE-------GIAKMI-YRPDNGEILGVHIFGLHAADLIHEASNAIALGTRI 529
Query 144 EDFDSTVGIHPTNAECFMQL 163
+D V HPT +E +L
Sbjct 530 QDIKLAVHAHPTLSEVLDEL 549
> ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrogenase
1); ATP binding / dihydrolipoyl dehydrogenase; K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 0/54 (0%)
Query 107 ICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECF 160
I K+ +++G+H + P AGE++ LAI A+ ED HPT +E
Sbjct 440 ILADKETDKILGVHIMAPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAL 493
> ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP
binding / dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=507
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 0/54 (0%)
Query 107 ICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECF 160
I K+ +++G+H + P AGE++ LAI A+ ED HPT +E
Sbjct 440 ILADKETDKILGVHIMSPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAI 493
> tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=519
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 0/53 (0%)
Query 107 ICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAEC 159
+ KD +++G +GPEAGE++ + L + GA ED T HPT +E
Sbjct 451 VLAHKDSDKLLGAWIMGPEAGELIGQLVLGMEYGAAAEDLGRTCVSHPTLSEA 503
> sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=499
Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query 93 DEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGI 152
+E+T++SP K++ +D +++G+H + +A E+L ++A+ LG T D
Sbjct 415 EENTTVSP--FIKVLIDSRD-MKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFP 471
Query 153 HPTNAECFMQ 162
HP+ +E F Q
Sbjct 472 HPSLSESFKQ 481
> tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putative
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=636
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 21/133 (15%)
Query 27 LEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEED 86
++H+P FT E +G +EE A+ ++ EV S H R
Sbjct 511 VKHIPAACFTSPEIAFIGDTEEAAMELGAKDGFEV--------GKSVSHF-----RANTK 557
Query 87 KGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDF 146
AE E E + K++ RKD +++G H +G A +++Q A AI + +D
Sbjct 558 AIAEGEGEG-------ILKVL-YRKDTGKILGCHMIGIHASDLIQECATAITNDISVKDL 609
Query 147 DSTVGIHPTNAEC 159
TV HPT +E
Sbjct 610 AFTVHTHPTLSEV 622
> eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydrogenase,
E3 component is part of three enzyme complexes (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=474
Score = 38.5 bits (88), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query 103 LAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPT 155
+ KLI K+ RV+G VG GE+L + LAI +G ED T+ HPT
Sbjct 396 MTKLI-FDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPT 447
> eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotide
transhydrogenase, soluble (EC:1.6.1.1); K00322 NAD(P) transhydrogenase
[EC:1.6.1.1]
Length=466
Score = 36.2 bits (82), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 28/162 (17%)
Query 2 LTPAAIRAGELLARRLFKNQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLEV 61
L AA G + A+ L K + +E +PT ++T E VG +E+ A ++V
Sbjct 318 LASAAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTA------MKV 371
Query 62 YLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHF 121
P EV + + + + ++ L I ++ + ++GIH
Sbjct 372 ------PYEVGRAQFKHLARA-----------QIVGMNVGTLK--ILFHRETKEILGIHC 412
Query 122 VGPEAGEVLQ-GMALAIRLGA--TKEDFDSTVGIHPTNAECF 160
G A E++ G A+ + G T E F +T +PT AE +
Sbjct 413 FGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAY 454
> tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 35.8 bits (81), Expect = 0.097, Method: Compositional matrix adjust.
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 0/52 (0%)
Query 109 LRKDKQRVVGIHFVGPEAGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECF 160
L ++ +++G +GP E++ ALAI GA+ ED HP+ +E
Sbjct 434 LSTEENKLLGAWMIGPHVSEMIHTTALAITYGASSEDVTRMCFAHPSLSEAI 485
> pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=666
Score = 33.1 bits (74), Expect = 0.50, Method: Composition-based stats.
Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 2/139 (1%)
Query 20 NQTEVFCLEHVPTTVFTPVEYGCVGLSEEDAIAKYGEENLEVYLREFSPLEVSACHRQKI 79
N ++ +++P+ +T E +GL+E++A Y +N+ V + + C
Sbjct 515 NLSKPILYKNIPSVCYTNPELAFIGLTEKEAKVLY-PDNVGVEISYYKSNSKILCENNIS 573
Query 80 KQRDEEDKGAEDEDEDTSLSPCCLAKLICLRKDKQRVVGIHFVGPEAGEVLQGMALAIRL 139
++++ + + + + K+I ++D + ++G+ VG A ++ LAI L
Sbjct 574 LNNNKKNNSYNKGQYNINDNTNGMVKII-YKEDTKEILGMFIVGNYASVLIHEAVLAINL 632
Query 140 GATKEDFDSTVGIHPTNAE 158
+ D V HPT +E
Sbjct 633 KLSAFDLAYMVHSHPTVSE 651
> cel:F52G3.4 hypothetical protein
Length=1009
Score = 31.2 bits (69), Expect = 2.1, Method: Composition-based stats.
Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 0/54 (0%)
Query 47 EEDAIAKYGEENLEVYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLSP 100
EE A + +EN E Y + L S ++ +Q++++D E+++ED S P
Sbjct 477 EEVAAIRKRKENPEDYYSNITELLRSQQEKKSAEQQEDQDVDMEEDNEDASAEP 530
> dre:100151626 tatdn1, MGC191238, MGC92362, zgc:92362; TatD DNase
domain containing 1 (EC:3.1.21.-); K03424 TatD DNase family
protein [EC:3.1.21.-]
Length=298
Score = 30.0 bits (66), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 10/65 (15%)
Query 126 AGEVLQGMALAIRLGATKEDFDSTVGIHPTNAECFMQ----------LQITKRSGENWVA 175
G L+ A+ L T+E F STVG HPT F L +T + + VA
Sbjct 50 TGGNLEDSRAALTLTHTREQFFSTVGCHPTRCSEFDDQGSDQYLSSLLDLTVSNTQKVVA 109
Query 176 AGGCG 180
G CG
Sbjct 110 VGECG 114
> pfa:PF08_0048 ATP-dependent helicase, putative; K01509 adenosinetriphosphatase
[EC:3.6.1.3]
Length=2082
Score = 30.0 bits (66), Expect = 4.6, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 0/43 (0%)
Query 57 ENLEVYLREFSPLEVSACHRQKIKQRDEEDKGAEDEDEDTSLS 99
E+ EVY S +E C +K DEE +DED +++LS
Sbjct 1610 EDSEVYRENSSDVEKYNCDVEKDNCDDEEKDNCDDEDMNSNLS 1652
Lambda K H
0.318 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 5106150148
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40