bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_0950_orf1
Length=166
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subu... 307 1e-83
cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain ... 254 9e-68
pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase... 240 2e-63
bbo:BBOV_III005740 17.m07511; protein kinase domain containing... 238 9e-63
tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subu... 231 1e-60
tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein ki... 225 5e-59
tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subu... 200 2e-51
xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent, ... 192 4e-49
cel:ZK909.2 kin-1; protein KINase family member (kin-1); K0434... 192 5e-49
xla:100101276 prkaca; protein kinase, cAMP-dependent, catalyti... 191 6e-49
mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP d... 190 2e-48
dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent... 190 2e-48
dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,... 189 3e-48
hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase, c... 189 5e-48
mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catal... 188 8e-48
dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;... 188 8e-48
sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K043... 187 9e-48
hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent, ... 187 1e-47
hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; prot... 187 1e-47
xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba; ... 186 3e-47
dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinas... 185 8e-47
sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase ... 183 3e-46
dre:561941 protein kinase, X-linked-like; K04345 protein kinas... 182 4e-46
sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 pro... 180 2e-45
mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.... 174 2e-43
hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1); K... 174 2e-43
cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:... 171 1e-42
hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,... 169 5e-42
dre:100125912 prkg2; protein kinase, cGMP-dependent, type II (... 167 1e-41
mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II; p... 167 1e-41
dre:556339 protein kinase, cGMP-dependent, type II-like; K0737... 166 3e-41
cel:C09G4.2 hypothetical protein 165 5e-41
mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b; p... 164 1e-40
hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK, P... 164 1e-40
dre:566430 cGMP dependent protein kinase I 163 2e-40
dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,... 162 7e-40
xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent, ty... 161 7e-40
tpv:TP02_0727 cAMP-dependent protein kinase catalytic subunit;... 160 2e-39
bbo:BBOV_I004190 19.m02221; cAMP-dependent protein kinase (EC:... 158 6e-39
dre:326020 fd58b04, wu:fd58b04; si:dkey-121j17.5 158 6e-39
cel:F55A8.2 egl-4; EGg Laying defective family member (egl-4);... 153 2e-37
tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11... 151 1e-36
hsa:10110 SGK2, H-SGK2, dJ138B7.2; serum/glucocorticoid regula... 150 3e-36
mmu:27219 Sgk2, AI098171, AW146006, Sgkl; serum/glucocorticoid... 149 5e-36
dre:324140 sgk1, cb1083, sgk, wu:fc20a09; serum/glucocorticoid... 147 1e-35
hsa:6446 SGK1, SGK; serum/glucocorticoid regulated kinase 1 (E... 147 1e-35
pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase, Pf... 147 2e-35
xla:399130 sgk1-a, Sgk, sgk-A, sgk1; serum/glucocorticoid regu... 146 3e-35
tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:... 146 4e-35
ath:AT5G62310 IRE; IRE (INCOMPLETE ROOT HAIR ELONGATION); kina... 146 4e-35
> tgo:TGME49_026030 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=343
Score = 307 bits (787), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 148/166 (89%), Positives = 156/166 (93%), Gaps = 0/166 (0%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RVF+A+R+DD APPVAIKRLKK+AVIRQKQVDHILSEKRILQ I HPFTVNMLGTF+DD
Sbjct 47 RVFMAKRKDDPHAPPVAIKRLKKAAVIRQKQVDHILSEKRILQMINHPFTVNMLGTFKDD 106
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLYIVM YVIGGEFF++LRK RRFENDAARFYAAQVT IFEYLH RNIIYRDLKPENLL
Sbjct 107 RYLYIVMEYVIGGEFFTLLRKTRRFENDAARFYAAQVTLIFEYLHDRNIIYRDLKPENLL 166
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
VD+EGYLKLTDFGFAKVIE RTYTLCGTPEYIAPEVLLNKGHGKPV
Sbjct 167 VDAEGYLKLTDFGFAKVIEYRTYTLCGTPEYIAPEVLLNKGHGKPV 212
> cpv:cgd3_3040 protein kinase, cAMP-dependent, catalytic chain
; K04345 protein kinase A [EC:2.7.11.11]
Length=392
Score = 254 bits (649), Expect = 9e-68, Method: Compositional matrix adjust.
Identities = 121/166 (72%), Positives = 141/166 (84%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RVFL++ ++D S AIKRLKKS VIRQKQVDHI +EK IL I+HPF V M GTF+DD
Sbjct 98 RVFLSKHKEDNSI--YAIKRLKKSVVIRQKQVDHITNEKAILSRIKHPFLVRMFGTFKDD 155
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLYI+M +VIGGEFF+ LR+ R F+N+ +RFYAAQV +FEYLHG+NIIYRDLKPEN+L
Sbjct 156 RYLYIMMEFVIGGEFFTYLRRCRHFDNETSRFYAAQVVLMFEYLHGKNIIYRDLKPENIL 215
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GYLKLTDFGFAK IE RT+TLCGTPEYIAPEVLLNKGHGKPV
Sbjct 216 IDKDGYLKLTDFGFAKAIEYRTFTLCGTPEYIAPEVLLNKGHGKPV 261
> pfa:PFI1685w PfPKAc, PfPKA, PKA; cAMP-dependent protein kinase
catalytic subunit; K04345 protein kinase A [EC:2.7.11.11]
Length=342
Score = 240 bits (612), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 108/164 (65%), Positives = 135/164 (82%), Gaps = 1/164 (0%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV LA ++ + PPVAIKR +K +IRQKQVDH+ SE++IL I HPF VN+ G+F+DD
Sbjct 47 RVILATYKN-GNYPPVAIKRFEKCKIIRQKQVDHVFSERKILNYINHPFCVNLHGSFKDD 105
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLY+V+ +VIGGEFF+ LR+N+RF ND FYAAQ+ IFEYL NI+YRDLKPENLL
Sbjct 106 SYLYLVLEFVIGGEFFTFLRRNKRFPNDVGCFYAAQIVLIFEYLQSLNIVYRDLKPENLL 165
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGK 164
+D +G++K+TDFGFAK++ETRTYTLCGTPEYIAPE+LLN GHGK
Sbjct 166 LDKDGFIKMTDFGFAKIVETRTYTLCGTPEYIAPEILLNVGHGK 209
> bbo:BBOV_III005740 17.m07511; protein kinase domain containing
protein; K04345 protein kinase A [EC:2.7.11.11]
Length=359
Score = 238 bits (606), Expect = 9e-63, Method: Compositional matrix adjust.
Identities = 113/167 (67%), Positives = 135/167 (80%), Gaps = 1/167 (0%)
Query 1 RVFLARRRD-DASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRD 59
RV LA + D P AIKRLKK ++I QKQVDH++SEK++L S+ HPF VNMLGTF+D
Sbjct 62 RVILAIPKGIDGITEPCAIKRLKKHSLIVQKQVDHVVSEKKLLSSVNHPFIVNMLGTFKD 121
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
+YLYIVM V GG+FF LR + E+++A FYAAQ+T IF+Y+H NIIYRDLKPENL
Sbjct 122 PHYLYIVMECVFGGDFFGYLRSVDKLESESAMFYAAQITCIFDYMHSHNIIYRDLKPENL 181
Query 120 LVDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
LV S+GYLKLTDFGFAKV+E RTYTLCGTPEY+APE+LLNKGHGK V
Sbjct 182 LVGSDGYLKLTDFGFAKVVELRTYTLCGTPEYLAPEILLNKGHGKAV 228
> tgo:TGME49_028420 cAMP-dependent protein kinase catalytic subunit,
putative (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=333
Score = 231 bits (588), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 108/159 (67%), Positives = 131/159 (82%), Gaps = 1/159 (0%)
Query 9 DDASAPP-VAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVM 67
D PP VA+K LKK+A+I+ K VDHI++EK+IL ++ HP TV G+F+D YLY+VM
Sbjct 44 DPTQVPPRVAVKLLKKAAIIKLKHVDHIINEKKILLALDHPLTVRCFGSFQDSRYLYLVM 103
Query 68 GYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYL 127
V GGEFF+ LRK +RF+ND ARFYAAQ+ IF+YLH +NIIYRDLKPEN+L+D +GY+
Sbjct 104 ELVPGGEFFTHLRKAKRFDNDTARFYAAQIVDIFDYLHSQNIIYRDLKPENMLLDKDGYV 163
Query 128 KLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
KLTDFGFAKV+E RT TLCGTPEYIAPEVLLNKGHGKPV
Sbjct 164 KLTDFGFAKVVEFRTDTLCGTPEYIAPEVLLNKGHGKPV 202
> tpv:TP02_0378 cAMP-dependent protein kinase; K04345 protein
kinase A [EC:2.7.11.11]
Length=352
Score = 225 bits (573), Expect = 5e-59, Method: Compositional matrix adjust.
Identities = 105/167 (62%), Positives = 138/167 (82%), Gaps = 1/167 (0%)
Query 1 RVFLA-RRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRD 59
+VFLA + ++D++ A+KRL+K +I QKQVDHI+SE ++L S+ HPF VN+LG+++D
Sbjct 58 KVFLALQEQEDSTTELCAVKRLEKYPLIAQKQVDHIISENKLLGSVSHPFIVNLLGSYKD 117
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
DYYLY+VM YV GG+FF+ LRKN R ++ A FYAAQVT +FEYLH NIIYRDLKPENL
Sbjct 118 DYYLYLVMEYVSGGDFFAYLRKNDRLKSYDAMFYAAQVTAMFEYLHDNNIIYRDLKPENL 177
Query 120 LVDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
L+ S+GYLKL DFGFAKV+E RT+TLCGTPEY++PE++L+ G+GK V
Sbjct 178 LLCSDGYLKLADFGFAKVVEFRTHTLCGTPEYMSPEIILHLGYGKAV 224
> tgo:TGME49_086470 cAMP-dependent protein kinase catalytic subunit
(EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=514
Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 89/153 (58%), Positives = 119/153 (77%), Gaps = 0/153 (0%)
Query 14 PPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGG 73
PP+A+K L K +++ KQV+H+ EKRIL SI+HPF VN+L F+D+ L+I+M YV GG
Sbjct 228 PPMALKILSKHKIVKMKQVEHVKDEKRILSSIEHPFIVNLLAAFQDEKRLFILMEYVNGG 287
Query 74 EFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFG 133
E FS LR+ D AR YAA++T F+YLH R+I+YRDLKPENLL+DS+G++K+TDFG
Sbjct 288 ELFSHLRRRNCIPTDQARLYAAEITLAFQYLHQRHIVYRDLKPENLLIDSQGHIKITDFG 347
Query 134 FAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
FAKV++ RT+TLCGT EY+APE + +GHG PV
Sbjct 348 FAKVVKDRTWTLCGTHEYLAPESITRRGHGLPV 380
> xla:446502 prkacbb, MGC80071; protein kinase, cAMP-dependent,
catalytic, beta b; K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 192 bits (488), Expect = 4e-49, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 125/166 (75%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R++++ S A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 57 RVMLVRQKENGSH--FAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYA+Q+ FEYLH ++IYRDLKPENLL
Sbjct 115 SNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> cel:ZK909.2 kin-1; protein KINase family member (kin-1); K04345
protein kinase A [EC:2.7.11.11]
Length=381
Score = 192 bits (488), Expect = 5e-49, Method: Compositional matrix adjust.
Identities = 93/166 (56%), Positives = 123/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + S A+K L K V++ KQV+H L+EKRILQ+I PF VNM +F+D+
Sbjct 87 RVMLVKHKQ--SGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDN 144
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+V+ ++ GGE FS LR+ RF +RFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 145 SNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLL 204
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+DS GYLK+TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 205 IDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 250
> xla:100101276 prkaca; protein kinase, cAMP-dependent, catalytic,
alpha (EC:2.7.11.1); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 124/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R +++ S A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 57 RVMLVRHKENGSH--FAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYA+Q+ FEYLH ++IYRDLKPENLL
Sbjct 115 TNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> mmu:18747 Prkaca, Cs, PKA, PKCD, Pkaca; protein kinase, cAMP
dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 123/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + ++ S A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 57 RVMLVKHKE--SGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 115 SNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> dre:564064 prkacaa, zgc:158799; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate a (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=352
Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 123/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + ++ S A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 58 RVMLVKHKE--SGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDN 115
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 116 TNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 175
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 176 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 221
> dre:445076 prkacab, zgc:91856; protein kinase, cAMP-dependent,
catalytic, alpha, genome duplicate b (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 189 bits (481), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 123/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R R+ + A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 57 RVMLVRHRE--TGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYA+Q+ FEYLH ++IYRDLKPENLL
Sbjct 115 TNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> hsa:5566 PRKACA, MGC102831, MGC48865, PKACA; protein kinase,
cAMP-dependent, catalytic, alpha (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 189 bits (479), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 89/166 (53%), Positives = 123/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + ++ + A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+
Sbjct 57 RVMLVKHKETGNH--YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 115 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> mmu:18749 Prkacb, Pkacb; protein kinase, cAMP dependent, catalytic,
beta (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=338
Score = 188 bits (477), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 124/166 (74%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + A+ A+K L K V++ KQ++H L+EKRILQ+++ PF V + +F+D+
Sbjct 44 RVMLVKHK--ATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDN 101
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 102 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 161
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 162 IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 207
> dre:563147 prkacbb, MGC110804, prkacb, wu:fz54b03, zgc:110804;
protein kinase, cAMP-dependent, catalytic, beta b; K04345
protein kinase A [EC:2.7.11.11]
Length=351
Score = 188 bits (477), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 92/166 (55%), Positives = 121/166 (72%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + AS A+K L K V++ KQV+H L+EKRILQ++ PF V + F+D+
Sbjct 57 RVLLVKHK--ASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 115 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> sce:YPL203W TPK2, PKA2, PKA3, YKR1; Tpk2p (EC:2.7.11.11); K04345
protein kinase A [EC:2.7.11.11]
Length=380
Score = 187 bits (476), Expect = 9e-48, Method: Compositional matrix adjust.
Identities = 85/150 (56%), Positives = 115/150 (76%), Gaps = 0/150 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
AIK LKK V++ KQV+H E+R+L+ ++HPF + M GTF+D +++VM Y+ GGE F
Sbjct 97 AIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELF 156
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S+LRK++RF N A+FYAA+V EYLH NIIYRDLKPEN+L+D G++K+TDFGFAK
Sbjct 157 SLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAK 216
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
++T T+TLCGTP+YIAPEV+ K + K V
Sbjct 217 EVQTVTWTLCGTPDYIAPEVITTKPYNKSV 246
> hsa:5568 PRKACG, KAPG, PKACg; protein kinase, cAMP-dependent,
catalytic, gamma (EC:2.7.11.11); K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 91/166 (54%), Positives = 122/166 (73%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R ++ A+K L K V++ KQV+HIL+EKRILQ+I PF V + +F+D+
Sbjct 57 RVMLVRHQETGGH--YAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLY+VM YV GGE FS L++ RF A FYAAQV +YLH ++I+RDLKPENLL
Sbjct 115 SYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GYL++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> hsa:5567 PRKACB, DKFZp781I2452, MGC41879, MGC9320, PKACB; protein
kinase, cAMP-dependent, catalytic, beta (EC:2.7.11.11);
K04345 protein kinase A [EC:2.7.11.11]
Length=351
Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 90/166 (54%), Positives = 122/166 (73%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + A+ A+K L K V++ KQ++H L+EKRILQ++ PF V + F+D+
Sbjct 57 RVMLVKHK--ATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDN 114
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM YV GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 115 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 174
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 175 IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> xla:380388 prkacb, MGC53163, XPKAbeta, kin-1, pkacb, prkacba;
protein kinase, cAMP-dependent, catalytic, beta; K04345 protein
kinase A [EC:2.7.11.11]
Length=351
Score = 186 bits (472), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 85/150 (56%), Positives = 116/150 (77%), Gaps = 0/150 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K L K V++ KQ++H L+EKRILQ++ PF V + +F+D+ LY++M YV GGE F
Sbjct 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMIMEYVPGGEMF 130
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL+D +GY+++TDFGFAK
Sbjct 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
> dre:393998 prkacba, MGC64054, Prkacb, zgc:64054; protein kinase,
cAMP-dependent, catalytic, beta a; K04345 protein kinase
A [EC:2.7.11.11]
Length=395
Score = 185 bits (469), Expect = 8e-47, Method: Compositional matrix adjust.
Identities = 88/166 (53%), Positives = 121/166 (72%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + S A+K L K V++ KQ++H L+EK+ILQ++ PF V + F+D+
Sbjct 101 RVMLVKHKQ--SEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDN 158
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM Y+ GGE FS LR+ RF ARFYAAQ+ FEYLH ++IYRDLKPENLL
Sbjct 159 SNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLL 218
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D +GY+++TDFGFAK ++ RT+TLCGTPEY+APE++L+KG+ K V
Sbjct 219 IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 264
> sce:YKL166C TPK3; Tpk3p (EC:2.7.11.11); K04345 protein kinase
A [EC:2.7.11.11]
Length=398
Score = 183 bits (464), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 82/150 (54%), Positives = 112/150 (74%), Gaps = 0/150 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K LKK +++ KQV+H E+R+L + HPF + M GTF+D +++VM Y+ GGE F
Sbjct 115 ALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELF 174
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S+LRK++RF N A+FYAA+V EYLH ++IIYRDLKPEN+L+D G++K+TDFGFAK
Sbjct 175 SLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK 234
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+ TYTLCGTP+YIAPEV+ K + K V
Sbjct 235 YVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 264
> dre:561941 protein kinase, X-linked-like; K04345 protein kinase
A [EC:2.7.11.11]
Length=357
Score = 182 bits (463), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 86/166 (51%), Positives = 114/166 (68%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RVFL + D + A+K +K VIR KQ H+ +EK +L + HPF V + T DD
Sbjct 61 RVFLVK--DKKTRGFFALKAMKIPDVIRLKQEQHVHNEKEVLTEVNHPFLVRLFWTHHDD 118
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
+LY++M YV GGE FS LR F N FY+A++ EYLH + I+YRDLKPEN+L
Sbjct 119 RFLYMLMEYVNGGELFSYLRSRGHFSNSTGMFYSAEIVCAIEYLHSKEIVYRDLKPENIL 178
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+DSEG+++LTDFGFAK + RT+TLCGTPEY+APEV+ +KGHG+ V
Sbjct 179 LDSEGHIRLTDFGFAKKLSERTWTLCGTPEYLAPEVIQSKGHGRAV 224
> sce:YJL164C TPK1, PKA1, SRA3; Tpk1p (EC:2.7.11.11); K04345 protein
kinase A [EC:2.7.11.11]
Length=397
Score = 180 bits (457), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 86/166 (51%), Positives = 117/166 (70%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R R + A+K LKK V+R KQV+H E+ +L + HPF + M GTF+D
Sbjct 100 RVHLIRSRHNGRY--YAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDA 157
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
++++M Y+ GGE FS+LRK++RF N A+FYAA+V EYLH ++IIYRDLKPEN+L
Sbjct 158 QQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL 217
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+D G++K+TDFGFAK + TYTLCGTP+YIAPEV+ K + K +
Sbjct 218 LDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSI 263
> mmu:19108 Prkx, PKX1, Pkare; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=355
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 79/151 (52%), Positives = 109/151 (72%), Gaps = 0/151 (0%)
Query 16 VAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEF 75
A+K + VIR KQ H+ +EK +L+ I HPF + +L T D+ +LY++M +V GGE
Sbjct 72 CALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGEL 131
Query 76 FSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFA 135
F+ LR RF + A+ FYA ++ EYLH + I+YRDLKPEN+L+D EG++KLTDFGFA
Sbjct 132 FTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFA 191
Query 136 KVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
K + RT+TLCGTPEY+APEV+ +KGHG+ V
Sbjct 192 KKLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 222
> hsa:5613 PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=358
Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 77/150 (51%), Positives = 108/150 (72%), Gaps = 0/150 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K + VIR KQ H+ +EK +L+ + HPF + + T+ D+ +LY++M YV GGE F
Sbjct 76 ALKVMSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELF 135
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S LR RF + FY+A++ EYLH + I+YRDLKPEN+L+D +G++KLTDFGFAK
Sbjct 136 SYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAK 195
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+ RT+TLCGTPEY+APEV+ +KGHG+ V
Sbjct 196 KLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 225
> cel:F47F2.1 hypothetical protein; K04345 protein kinase A [EC:2.7.11.11]
Length=398
Score = 171 bits (432), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 80/166 (48%), Positives = 110/166 (66%), Gaps = 2/166 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV LAR D + A+K L V+ +Q H+ +EKR+L ++HPF V M + +D
Sbjct 103 RVELAR--DKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDS 160
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
+LY++M +V GGE FS LR +R F N ARFYA+++ EY+H I+YRDLKPENL+
Sbjct 161 NHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLM 220
Query 121 VDSEGYLKLTDFGFAKVIETRTYTLCGTPEYIAPEVLLNKGHGKPV 166
+ EG++K+ DFGFAK + RTYT+CGTP+Y+APE L GH K V
Sbjct 221 LSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLARTGHNKGV 266
> hsa:5593 PRKG2, PRKGR2, cGKII; protein kinase, cGMP-dependent,
type II (EC:2.7.11.12); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=762
Score = 169 bits (427), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 81/164 (49%), Positives = 116/164 (70%), Gaps = 4/164 (2%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + +++ A A+K ++K ++ KQ +H+ SEKRIL+ + PF V + TF+D+
Sbjct 466 RVELVKVKNENVA--FAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDN 523
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
Y+Y+++ +GGE +S+LR F+ ++F A VT F+YLH IIYRDLKPENL+
Sbjct 524 KYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLI 583
Query 121 VDSEGYLKLTDFGFAKVIET--RTYTLCGTPEYIAPEVLLNKGH 162
+D+EGYLKL DFGFAK I + +T+T CGTPEY+APEV+LNKGH
Sbjct 584 LDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGH 627
> dre:100125912 prkg2; protein kinase, cGMP-dependent, type II
(EC:2.7.11.1); K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=768
Score = 167 bits (423), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 77/152 (50%), Positives = 107/152 (70%), Gaps = 2/152 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K +KK ++ +Q +HI SE+RIL PF V M T++D+ Y+Y+++ +GGE +
Sbjct 486 ALKCIKKRHIVDNRQEEHIYSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIW 545
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S+LR FE A+F VT F+YLH IIYRDLKPENL++D++GY+KL DFGFAK
Sbjct 546 SLLRDRGSFEEYTAKFCVGCVTEAFDYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAK 605
Query 137 VIET--RTYTLCGTPEYIAPEVLLNKGHGKPV 166
++ RT+T CGTPEY+APE++LNKGHG V
Sbjct 606 KLKCGQRTWTFCGTPEYVAPEIILNKGHGLSV 637
> mmu:19092 Prkg2, AW212535, CGKII, MGC130517, Prkgr2, cGK-II;
protein kinase, cGMP-dependent, type II (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=762
Score = 167 bits (423), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 80/164 (48%), Positives = 116/164 (70%), Gaps = 4/164 (2%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + +++ A A+K ++K ++ KQ +H+ SEKRIL+ + PF V + TF+D+
Sbjct 466 RVELVKVKNENVA--FAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDN 523
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
Y+Y+++ +GGE +S+LR F+ ++F A VT F+YLH IIYRDLKPENL+
Sbjct 524 KYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLI 583
Query 121 VDSEGYLKLTDFGFAKVIET--RTYTLCGTPEYIAPEVLLNKGH 162
+D++GYLKL DFGFAK I + +T+T CGTPEY+APEV+LNKGH
Sbjct 584 LDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGH 627
> dre:556339 protein kinase, cGMP-dependent, type II-like; K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=730
Score = 166 bits (420), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 77/155 (49%), Positives = 106/155 (68%), Gaps = 2/155 (1%)
Query 10 DASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGY 69
D+ A+K +KK ++ +Q +HI SEK ILQ F V + TFRDD ++Y+++
Sbjct 441 DSEDTAFALKCIKKKHIVDTRQQEHIYSEKIILQQTNSNFIVRLFRTFRDDKFVYMLLEV 500
Query 70 VIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKL 129
+GGE +S+LR F+ ARF V F+YLHG+ I+YRDLKPENLL+D+EGY+K+
Sbjct 501 CLGGELWSLLRDMSCFDEPTARFCTGCVLEAFDYLHGKGIVYRDLKPENLLLDAEGYVKM 560
Query 130 TDFGFAKVI--ETRTYTLCGTPEYIAPEVLLNKGH 162
DFGFAK I +T+T CGTPEY+APEV++NKGH
Sbjct 561 ADFGFAKKIGLGKKTWTFCGTPEYVAPEVIMNKGH 595
> cel:C09G4.2 hypothetical protein
Length=617
Score = 165 bits (418), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 79/164 (48%), Positives = 110/164 (67%), Gaps = 5/164 (3%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L R AS+ A+K + K+ ++ KQ H++SE+RIL + + V M T+RD
Sbjct 323 RVELVR---SASSRTYALKIMNKAHIVETKQESHVVSERRILMQCDNDYIVRMYKTYRDS 379
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
+Y++M +GGE +++LRK RF+ND RFY A EYLH +NI+YRDLKPEN+L
Sbjct 380 EKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLHRKNIVYRDLKPENML 439
Query 121 VDSEGYLKLTDFGFAKVIET--RTYTLCGTPEYIAPEVLLNKGH 162
+D G+ KL DFGFAK ++ RT+T CGT EY+APE++LNKGH
Sbjct 440 LDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPEIVLNKGH 483
> mmu:19091 Prkg1, AW125416, CGKI, MGC132849, Prkg1b, Prkgr1b;
protein kinase, cGMP-dependent, type I (EC:2.7.11.12); K07376
protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 81/164 (49%), Positives = 108/164 (65%), Gaps = 3/164 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + + S A+K LKK ++ +Q +HI SEK+I+Q F V + TF+D
Sbjct 373 RVELVQLKSEESKT-FAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDS 431
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLY++M +GGE +++LR FE+ RFY A V F YLH + IIYRDLKPENL+
Sbjct 432 KYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLI 491
Query 121 VDSEGYLKLTDFGFAKVI--ETRTYTLCGTPEYIAPEVLLNKGH 162
+D GY KL DFGFAK I +T+T CGTPEY+APE++LNKGH
Sbjct 492 LDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535
> hsa:5592 PRKG1, CGKI, DKFZp686K042, FLJ36117, MGC71944, PGK,
PKG, PRKG1B, PRKGR1B, cGKI-BETA, cGKI-alpha; protein kinase,
cGMP-dependent, type I (EC:2.7.11.12); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=671
Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 81/164 (49%), Positives = 108/164 (65%), Gaps = 3/164 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + + S A+K LKK ++ +Q +HI SEK+I+Q F V + TF+D
Sbjct 373 RVELVQLKSEESKT-FAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDS 431
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLY++M +GGE +++LR FE+ RFY A V F YLH + IIYRDLKPENL+
Sbjct 432 KYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLI 491
Query 121 VDSEGYLKLTDFGFAKVI--ETRTYTLCGTPEYIAPEVLLNKGH 162
+D GY KL DFGFAK I +T+T CGTPEY+APE++LNKGH
Sbjct 492 LDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535
> dre:566430 cGMP dependent protein kinase I
Length=528
Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 77/148 (52%), Positives = 101/148 (68%), Gaps = 2/148 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K LKK ++ +Q +HI SEK+I+Q F V + TF+D YLY++M +GGE +
Sbjct 245 AMKILKKRHIVDTRQQEHIRSEKQIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELW 304
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
++LR FE+ RFY A V F YLH + IIYRDLKPENL++D GY KL DFGFAK
Sbjct 305 TILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAK 364
Query 137 VI--ETRTYTLCGTPEYIAPEVLLNKGH 162
I +T+T CGTPEY+APE++LNKGH
Sbjct 365 KIGFGKKTWTFCGTPEYVAPEIILNKGH 392
> dre:394005 prkg1a, MGC63955, prkg1, zgc:63955; protein kinase,
cGMP-dependent, type Ia (EC:2.7.11.1); K07376 protein kinase,
cGMP-dependent [EC:2.7.11.12]
Length=667
Score = 162 bits (409), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 80/164 (48%), Positives = 106/164 (64%), Gaps = 3/164 (1%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RV L + + D A+K LKK ++ +Q +HI SEK I+Q F V + TF+D
Sbjct 369 RVELVQLKSD-EMKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDS 427
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
YLY++M +GGE +++LR F++ RFY A V F YLH + IIYRDLKPENL+
Sbjct 428 KYLYMLMEACLGGELWTILRDRGNFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLI 487
Query 121 VDSEGYLKLTDFGFAKVI--ETRTYTLCGTPEYIAPEVLLNKGH 162
+D GY KL DFGFAK I +T+T CGTPEY+APE++LNKGH
Sbjct 488 LDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 531
> xla:444025 prkg2, MGC82580; protein kinase, cGMP-dependent,
type II (EC:2.7.11.1); K07376 protein kinase, cGMP-dependent
[EC:2.7.11.12]
Length=783
Score = 161 bits (408), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 75/148 (50%), Positives = 102/148 (68%), Gaps = 2/148 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K +KK ++ Q +HI SEK IL+ PF V + TF+D+ Y+Y+++ +GGE +
Sbjct 501 AMKCIKKRHIVDNMQQEHIHSEKNILKEACSPFIVKLYCTFKDNKYVYMLLEACLGGELW 560
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S+LR F+ A+F VT EYLH ++YRDLKPENLL+DSEGY+KL DFGFAK
Sbjct 561 SILRDRGSFDETTAKFCTGCVTEALEYLHQIGVLYRDLKPENLLLDSEGYVKLVDFGFAK 620
Query 137 VI--ETRTYTLCGTPEYIAPEVLLNKGH 162
+ +T+T CGTPEY+APEV+LNKGH
Sbjct 621 KVFPGQKTWTFCGTPEYVAPEVILNKGH 648
> tpv:TP02_0727 cAMP-dependent protein kinase catalytic subunit;
K04345 protein kinase A [EC:2.7.11.11]
Length=511
Score = 160 bits (405), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 72/148 (48%), Positives = 108/148 (72%), Gaps = 1/148 (0%)
Query 16 VAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEF 75
V++K L K+ +I ++Q++H+ +EK IL +++HPF V LG+F+D LY ++ +V GGE
Sbjct 230 VSLKILSKNKIIEKRQLEHVKNEKNILSTLKHPFIVGYLGSFQDTLNLYFILEFVPGGEL 289
Query 76 FSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFA 135
F+ LR+ F + RFYA+QV +YLH ++YRDLKPEN+L+D GY++L DFGFA
Sbjct 290 FTYLRRMHTFPPEYTRFYASQVLLALDYLHMNKLVYRDLKPENILLDIMGYIRLVDFGFA 349
Query 136 KVIET-RTYTLCGTPEYIAPEVLLNKGH 162
K +E+ +TYT+CGT +Y+APE+ L KGH
Sbjct 350 KRLESGKTYTVCGTCDYLAPEIFLKKGH 377
> bbo:BBOV_I004190 19.m02221; cAMP-dependent protein kinase (EC:2.7.11.1);
K04345 protein kinase A [EC:2.7.11.11]
Length=416
Score = 158 bits (400), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 71/147 (48%), Positives = 106/147 (72%), Gaps = 0/147 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K L K+ VI ++QV H+ +E+ IL +++HPF VN + +F+DD +YI++ YV GGE F
Sbjct 135 ALKILHKTKVIAERQVMHLRNERHILSTVRHPFIVNYVKSFQDDINVYILLEYVSGGELF 194
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
S + K + ARFY AQ ++LH + I+YRDLKPEN+L+D +G+++L DFGFAK
Sbjct 195 SYIYKYGALGHTVARFYTAQAILAIDFLHFKGIVYRDLKPENMLLDQDGHIRLVDFGFAK 254
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGHG 163
++ +TYT+CGT +Y+APE+ L GHG
Sbjct 255 EVKHKTYTVCGTHDYLAPEIFLRCGHG 281
> dre:326020 fd58b04, wu:fd58b04; si:dkey-121j17.5
Length=663
Score = 158 bits (400), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 73/148 (49%), Positives = 104/148 (70%), Gaps = 2/148 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+KR+ K V+ +KQ HIL EK+ILQ+I+ F V + F+D Y+Y++M + GGE +
Sbjct 383 AMKRISKQHVVAKKQEAHILLEKKILQAIRCDFIVRLHAAFKDSRYVYMIMEFCPGGEIW 442
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
+ L++ RFE A F A V + YLH + I+YRDLKPENL++DS+GY+KL DFGFAK
Sbjct 443 TKLKEAGRFEEKIAVFITACVVEAYAYLHNKGILYRDLKPENLMLDSKGYVKLVDFGFAK 502
Query 137 VIE--TRTYTLCGTPEYIAPEVLLNKGH 162
+ +TY+ CGTPEYI+PE++ N+GH
Sbjct 503 ELSRGEKTYSFCGTPEYISPEIIQNQGH 530
> cel:F55A8.2 egl-4; EGg Laying defective family member (egl-4);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=780
Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 70/152 (46%), Positives = 102/152 (67%), Gaps = 2/152 (1%)
Query 13 APPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIG 72
A A+K LKK ++ +Q +HI +E+ I+ + V + TFRD ++Y+++ +G
Sbjct 493 AKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLG 552
Query 73 GEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDF 132
GE ++ LR F++ ARFY A V EYLH +NI+YRDLKPEN L+ + GYLKL DF
Sbjct 553 GELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDF 612
Query 133 GFAKVIET--RTYTLCGTPEYIAPEVLLNKGH 162
GFAK + + +T+T CGTPEY++PE++LNKGH
Sbjct 613 GFAKKLASGRKTWTFCGTPEYVSPEIILNKGH 644
> tgo:TGME49_067540 protein kinase, putative (EC:4.1.1.70 2.7.11.13)
Length=951
Score = 151 bits (381), Expect = 1e-36, Method: Composition-based stats.
Identities = 74/153 (48%), Positives = 102/153 (66%), Gaps = 3/153 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K L+K AV+R+ QV+H +E+ +L + HPF V M F+ LY V+ Y GGE F
Sbjct 486 AMKMLRKEAVVRRNQVEHTRTERDVLAWVSHPFIVQMHYAFQTRKKLYFVLEYCPGGELF 545
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
L + RF+ AA FYAA+V E+LH N++YRDLKPEN+L+D G+++LTDFG +K
Sbjct 546 FHLSRAGRFKEYAACFYAAEVLLALEHLHKYNVVYRDLKPENVLLDEHGHVRLTDFGLSK 605
Query 137 V-IETR--TYTLCGTPEYIAPEVLLNKGHGKPV 166
+E +LCGTPEY+APE+L +GHGK V
Sbjct 606 EGVEDNCSARSLCGTPEYLAPEILSQQGHGKAV 638
> hsa:10110 SGK2, H-SGK2, dJ138B7.2; serum/glucocorticoid regulated
kinase 2 (EC:2.7.11.1); K13303 serum/glucocorticoid-regulated
kinase 2 [EC:2.7.11.1]
Length=367
Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 76/161 (47%), Positives = 110/161 (68%), Gaps = 6/161 (3%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRIL-QSIQHPFTVNMLGTFRD 59
+V LA+R+ D + A+K L+K +++++K+ HI++E+ +L ++++HPF V + +F+
Sbjct 48 KVLLAKRKSDGAF--YAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQT 105
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
LY V+ YV GGE F L++ RRF ARFYAA+V + YLH NIIYRDLKPEN+
Sbjct 106 PEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENI 165
Query 120 LVDSEGYLKLTDFGFAK---VIETRTYTLCGTPEYIAPEVL 157
L+D +G++ LTDFG K E T T CGTPEY+APEVL
Sbjct 166 LLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVL 206
> mmu:27219 Sgk2, AI098171, AW146006, Sgkl; serum/glucocorticoid
regulated kinase 2 (EC:2.7.11.1); K13303 serum/glucocorticoid-regulated
kinase 2 [EC:2.7.11.1]
Length=367
Score = 149 bits (376), Expect = 5e-36, Method: Compositional matrix adjust.
Identities = 75/161 (46%), Positives = 109/161 (67%), Gaps = 6/161 (3%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRIL-QSIQHPFTVNMLGTFRD 59
+V LA+R+ D + A+K L+K ++++ K+ +HI++E+ +L ++++HPF V + +F+
Sbjct 48 KVLLAKRKSDGAF--YAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQT 105
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
LY V+ YV GGE F L++ RRF ARFY A+V + YLH NIIYRDLKPEN+
Sbjct 106 PEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENI 165
Query 120 LVDSEGYLKLTDFGFAKVI---ETRTYTLCGTPEYIAPEVL 157
L+D +G++ LTDFG K E T T CGTPEY+APEVL
Sbjct 166 LLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVL 206
> dre:324140 sgk1, cb1083, sgk, wu:fc20a09; serum/glucocorticoid
regulated kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=433
Score = 147 bits (372), Expect = 1e-35, Method: Compositional matrix adjust.
Identities = 79/169 (46%), Positives = 112/169 (66%), Gaps = 10/169 (5%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRIL-QSIQHPFTVNMLGTFRD 59
+V LAR R D A+K L+K A++++K+ HI+SE+ +L ++++HPF V + +F+
Sbjct 113 KVLLARHRSDEKF--YAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHYSFQT 170
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
LY V+ Y+ GGE F L++ R F ARFYAA++ + YLH NI+YRDLKPEN+
Sbjct 171 TDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENI 230
Query 120 LVDSEGYLKLTDFGFAKV-IETR--TYTLCGTPEYIAPEVLLNKGHGKP 165
L+DS+G++ LTDFG K IE T T CGTPEY+APEVL H +P
Sbjct 231 LLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVL----HKQP 275
> hsa:6446 SGK1, SGK; serum/glucocorticoid regulated kinase 1
(EC:2.7.11.1); K13302 serum/glucocorticoid-regulated kinase
1 [EC:2.7.11.1]
Length=526
Score = 147 bits (372), Expect = 1e-35, Method: Composition-based stats.
Identities = 77/170 (45%), Positives = 114/170 (67%), Gaps = 6/170 (3%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRIL-QSIQHPFTVNMLGTFRD 59
+V LAR + A A+K L+K A++++K+ HI+SE+ +L ++++HPF V + +F+
Sbjct 206 KVLLARHK--AEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQT 263
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
LY V+ Y+ GGE F L++ R F ARFYAA++ + YLH NI+YRDLKPEN+
Sbjct 264 ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENI 323
Query 120 LVDSEGYLKLTDFGFAKV-IE--TRTYTLCGTPEYIAPEVLLNKGHGKPV 166
L+DS+G++ LTDFG K IE + T T CGTPEY+APEVL + + + V
Sbjct 324 LLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTV 373
> pfa:PFL2250c PKB; rac-beta serine/threonine protein kinase,
PfPKB (EC:2.7.1.-); K08286 protein-serine/threonine kinase [EC:2.7.11.-]
Length=735
Score = 147 bits (370), Expect = 2e-35, Method: Composition-based stats.
Identities = 72/153 (47%), Positives = 102/153 (66%), Gaps = 3/153 (1%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K L+K ++ + Q++H E+ IL+ + HPF V M F+ LY ++ Y GGE F
Sbjct 430 AMKILRKENILSRNQLEHTKVERNILKCVSHPFIVKMYYAFQTKQKLYFILEYCPGGELF 489
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
L K R F + A+FY++++ EYLH NIIYRDLKPEN+L+D G+++LTDFG +K
Sbjct 490 FHLSKLREFSEETAKFYSSEIILALEYLHDLNIIYRDLKPENVLLDELGHIRLTDFGLSK 549
Query 137 --VIETR-TYTLCGTPEYIAPEVLLNKGHGKPV 166
+ ET T +LCGTPEY+APE++ KGHGK V
Sbjct 550 EGITETNLTKSLCGTPEYLAPEIIEQKGHGKAV 582
> xla:399130 sgk1-a, Sgk, sgk-A, sgk1; serum/glucocorticoid regulated
kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated
kinase 1 [EC:2.7.11.1]
Length=434
Score = 146 bits (368), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 77/169 (45%), Positives = 112/169 (66%), Gaps = 10/169 (5%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRIL-QSIQHPFTVNMLGTFRD 59
+V LAR + D A+K L+K A++++K+ HI+SE+ +L ++++HPF V + +F+
Sbjct 114 KVLLARHQADEKF--YAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQT 171
Query 60 DYYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENL 119
LY ++ Y+ GGE F L++ R F ARFYAA++ + YLH NI+YRDLKPEN+
Sbjct 172 TSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENI 231
Query 120 LVDSEGYLKLTDFGFAKV-IETR--TYTLCGTPEYIAPEVLLNKGHGKP 165
L+DS+G++ LTDFG K IE T T CGTPEY+APEVL H +P
Sbjct 232 LLDSQGHIVLTDFGLCKENIEPNGTTSTFCGTPEYLAPEVL----HKQP 276
> tgo:TGME49_111360 cGMP-dependent protein kinase, putative (EC:2.7.11.12);
K07376 protein kinase, cGMP-dependent [EC:2.7.11.12]
Length=994
Score = 146 bits (368), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 70/146 (47%), Positives = 94/146 (64%), Gaps = 0/146 (0%)
Query 17 AIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDDYYLYIVMGYVIGGEFF 76
A+K + + +VI Q HI E+ I+ HPF + ++ TFRD +LY + V GGE +
Sbjct 711 ALKCVSRRSVIALSQQQHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELY 770
Query 77 SVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLLVDSEGYLKLTDFGFAK 136
+RK A+FY A + EYLH RNI YRDLKPEN+L+DS+GY+KL DFG AK
Sbjct 771 DAIRKLGLLARSQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAK 830
Query 137 VIETRTYTLCGTPEYIAPEVLLNKGH 162
++ R YTL GTP Y+APEV+L KG+
Sbjct 831 KMQGRAYTLVGTPHYMAPEVILGKGY 856
> ath:AT5G62310 IRE; IRE (INCOMPLETE ROOT HAIR ELONGATION); kinase/
protein serine/threonine kinase
Length=1168
Score = 146 bits (368), Expect = 4e-35, Method: Composition-based stats.
Identities = 80/198 (40%), Positives = 113/198 (57%), Gaps = 36/198 (18%)
Query 1 RVFLARRRDDASAPPVAIKRLKKSAVIRQKQVDHILSEKRILQSIQHPFTVNMLGTFRDD 60
RVFLA++R A+ AIK LKK+ +IR+ V+ IL+E+ IL S+++PF V +F
Sbjct 767 RVFLAKKR--ATGDLFAIKVLKKADMIRKNAVESILAERNILISVRNPFVVRFFYSFTCR 824
Query 61 YYLYIVMGYVIGGEFFSVLRKNRRFENDAARFYAAQVTTIFEYLHGRNIIYRDLKPENLL 120
LY+VM Y+ GG+ FS+LR + D AR Y A+V EYLH NII+RDLKP+NLL
Sbjct 825 ENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPDNLL 884
Query 121 VDSEGYLKLTDFGFAKV----------------------------------IETRTYTLC 146
++ +G++KLTDFG +KV + + +
Sbjct 885 INQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSKAQHSQGKDSRKKHAVV 944
Query 147 GTPEYIAPEVLLNKGHGK 164
GTP+Y+APE+LL GHGK
Sbjct 945 GTPDYLAPEILLGMGHGK 962
Lambda K H
0.325 0.142 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4027755848
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40