bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_1197_orf1
Length=112
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.... 138 4e-33
ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP ... 114 1e-25
hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehy... 114 1e-25
dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase (E... 113 2e-25
mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogen... 112 2e-25
ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrog... 110 1e-24
xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1... 110 1e-24
cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehyd... 109 2e-24
bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase (E... 105 5e-23
sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the li... 102 4e-22
tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00... 76.6 2e-14
sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogena... 74.3 8e-14
pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihy... 70.1 1e-12
eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydroge... 70.1 2e-12
pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4); ... 67.8 9e-12
ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoa... 63.9 1e-10
ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrol... 63.2 2e-10
tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putativ... 60.1 2e-09
dre:100332932 glutathione reductase-like 53.5 2e-07
ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase); ... 51.2 8e-07
cel:F20D6.11 hypothetical protein 50.8 1e-06
eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide... 50.4 1e-06
hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7); K0... 44.3 1e-04
mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione re... 43.5 2e-04
mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase 3... 43.1 2e-04
eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotid... 43.1 2e-04
dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathi... 42.7 3e-04
sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathio... 40.4 0.001
mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:... 38.9 0.004
hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3 (E... 38.5 0.005
tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7) 37.4 0.013
ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding / gl... 36.6 0.018
tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7)... 36.2 0.025
tgo:TGME49_007620 pyridine nucleotide-disulphide oxidoreductas... 35.8 0.034
ath:AT3G52880 ATMDAR1; monodehydroascorbate reductase, putativ... 35.8 0.036
xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1... 35.8 0.037
eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreducta... 35.4 0.039
tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7)... 35.4 0.039
cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin red... 35.4 0.048
pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 gluta... 35.0 0.052
tpv:TP03_0672 oxidoreductase 35.0 0.064
ath:AT5G03630 ATMDAR2; monodehydroascorbate reductase (NADH); ... 34.7 0.068
dre:100150876 apoptosis-inducing factor, mitochondrion-associa... 34.7 0.085
dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredo... 34.7 0.087
hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thior... 34.3 0.095
cel:C46F11.2 hypothetical protein 32.3 0.42
mmu:72168 Aifm3, 2810401C16Rik, AI840249, Aifl; apoptosis-indu... 31.6 0.66
xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1... 31.2 0.83
dre:557064 apoptosis-inducing factor, mitochondrion-associated... 31.2 0.88
dre:555791 MGC162952; zgc:162952 31.2 0.95
> tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=519
Score = 138 bits (348), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 67/111 (60%), Positives = 86/111 (77%), Gaps = 2/111 (1%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
+IGLELGSVWRN+GAEVTVVEF D+++P +D E+ +AFQK +E+ GIKF TKVVG+
Sbjct 233 VIGLELGSVWRNLGAEVTVVEFLDRLLPPVDGEVAKAFQKEMEKTGIKFQLGTKVVGADV 292
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
+ TL +E AK G+ ++ DVVLVAVGRRPYT++LGLEELGIE D+
Sbjct 293 RESS--ATLHVEPAKGGNPFEMEADVVLVAVGRRPYTKNLGLEELGIETDR 341
> ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP
binding / dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=507
Score = 114 bits (284), Expect = 1e-25, Method: Composition-based stats.
Identities = 59/110 (53%), Positives = 76/110 (69%), Gaps = 2/110 (1%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLE+GSVW +G+EVTVVEF I+PA+D EI + FQ+ LE+Q +KFM TKVVG S
Sbjct 225 IGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMKFMLKTKVVGVDSS 284
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
D V L +E A+ G+ L DVVLV+ GR P+T L LE++G+E DK
Sbjct 285 --GDGVKLIVEPAEGGEQTTLEADVVLVSAGRTPFTSGLDLEKIGVETDK 332
> hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=509
Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 55/113 (48%), Positives = 82/113 (72%), Gaps = 2/113 (1%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP-ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+IG+ELGSVW+ +GA+VT VEF + +D+EI + FQ++L++QG KF +TKV G+
Sbjct 223 VIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGAT 282
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
K ++ ++ + +E A G + CDV+LV +GRRP+T++LGLEELGIELD R
Sbjct 283 KKSDG-KIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPR 334
> dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 56/113 (49%), Positives = 82/113 (72%), Gaps = 2/113 (1%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP-ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+IG+ELGSVW+ +GA+VT VEF + +D+EI + FQ++L++QG+KF STKV+G+
Sbjct 221 VIGVELGSVWQRLGAKVTAVEFLGHVGGMGIDMEISKNFQRILQKQGLKFKLSTKVMGAT 280
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
K + ++ + +E A G L CDV+LV +GRRP+T +LGLE +GIELDKR
Sbjct 281 K-RPDGKIDVAVEAAAGGKNETLTCDVLLVCIGRRPFTGNLGLESVGIELDKR 332
> mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 55/113 (48%), Positives = 82/113 (72%), Gaps = 2/113 (1%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP-ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+IG+ELGSVW+ +GA+VT VEF + +D+EI + FQ++L+RQG KF +TKV G+
Sbjct 223 VIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQRQGFKFKLNTKVTGAT 282
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
K ++ ++ + +E A G + CDV+LV +GRRP+T++LGLEELGIELD +
Sbjct 283 KKSDG-KIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPK 334
> ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrogenase
1); ATP binding / dihydrolipoyl dehydrogenase; K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 110 bits (275), Expect = 1e-24, Method: Composition-based stats.
Identities = 57/110 (51%), Positives = 76/110 (69%), Gaps = 2/110 (1%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLE+GSVW +G+EVTVVEF I+P++D EI + FQ+ LE+Q +KFM TKVV S
Sbjct 225 IGLEMGSVWGRLGSEVTVVEFAGDIVPSMDGEIRKQFQRSLEKQKMKFMLKTKVVSVDSS 284
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
+D V L +E A+ G+ L DVVLV+ GR P+T L LE++G+E DK
Sbjct 285 --SDGVKLTVEPAEGGEQSILEADVVLVSAGRTPFTSGLDLEKIGVETDK 332
> xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 54/113 (47%), Positives = 80/113 (70%), Gaps = 2/113 (1%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP-ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+IG+ELGSVW+ +GA+VT VEF + +D+EI + F ++L++QG+KF STKV G+
Sbjct 223 VIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFHRILQKQGLKFKLSTKVTGAS 282
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
K + ++ + +E A G + CDV+LV +GRRP+T +LGL+ELGIELD R
Sbjct 283 K-RPDGKIDVSIEAAAGGKEEVITCDVLLVCIGRRPFTENLGLQELGIELDNR 334
> cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=495
Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 56/113 (49%), Positives = 76/113 (67%), Gaps = 3/113 (2%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP-ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+IGLELGSVW+ +GAEVT VEF + +D E+ + FQ+ L +QG KF+ +TKV+G+
Sbjct 209 VIGLELGSVWQRLGAEVTAVEFLGHVGGMGIDGEVSKNFQRSLTKQGFKFLLNTKVMGA- 267
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
S +T+E+E AK G L CD +LV+VGRRPYT LGL + I+LD R
Sbjct 268 -SQNGSTITVEVEGAKDGKKQTLECDTLLVSVGRRPYTEGLGLSNVQIDLDNR 319
> bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=481
Score = 105 bits (261), Expect = 5e-23, Method: Composition-based stats.
Identities = 50/110 (45%), Positives = 79/110 (71%), Gaps = 4/110 (3%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLEL SVW +GA+VT+VE+ + + +D ++ A +K++E+QGI + STKV+G +
Sbjct 201 IGLELASVWSRLGAKVTIVEYANNLCHTMDHDVSVAIKKIVEKQGINILLSTKVLGGEVK 260
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
++ +T E K G+ ++L DVVL+A+GRRPYT++LGLEELGI+ ++
Sbjct 261 DDCAVITAE----KDGEKIELKGDVVLLAMGRRPYTKNLGLEELGIKTER 306
> sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the
lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase
and 2-oxoglutarate dehydrogenase multi-enzyme complexes
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 48/109 (44%), Positives = 79/109 (72%), Gaps = 0/109 (0%)
Query 4 LELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKSNE 63
LE+GSV+ +G++VTVVEF +I ++D E+ +A QK L++QG+ F STKV+ ++++++
Sbjct 217 LEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDD 276
Query 64 NDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ V + +E+ K+ L +V+LVAVGRRPY LG E++G+E+DKR
Sbjct 277 KNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKR 325
> tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 43/109 (39%), Positives = 67/109 (61%), Gaps = 4/109 (3%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLEL SVW +G++V + EF ++I +D ++ +K+LE+QG+ TKV+ ++ +
Sbjct 200 IGLELASVWSRLGSKVDIFEFNNQICSVMDTDVCVTMRKILEKQGLNIHTGTKVLNAKVT 259
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELD 110
N +T E E G + D VLVA+GR PYT LG+++LG+ LD
Sbjct 260 NNTVTLTTESE----GKEMSYVGDKVLVAMGRVPYTEGLGIDKLGVTLD 304
> sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=499
Score = 74.3 bits (181), Expect = 8e-14, Method: Composition-based stats.
Identities = 40/111 (36%), Positives = 68/111 (61%), Gaps = 3/111 (2%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLE+ ++ N+G+ VT+VE +I +D E+ A + LL+ QGI F+ T+V ++ +
Sbjct 201 IGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLDTRVQLAE-A 259
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ ++ + L N S T HCDV++V++GRRP + L + +G LD+R
Sbjct 260 DAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIG--LDER 308
> pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=512
Score = 70.1 bits (170), Expect = 1e-12, Method: Composition-based stats.
Identities = 36/104 (34%), Positives = 65/104 (62%), Gaps = 2/104 (1%)
Query 8 SVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKSNENDEV 67
SV+ +G++VTV E+ +++ LD ++ + QK LE+ +KF+F+T V+G + EN++
Sbjct 228 SVFSKLGSDVTVFEYNERLCGFLDADVSKVLQKTLEKIKMKFVFNTSVIGG--NIENNQA 285
Query 68 TLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
L +N K+ + K ++VL+ +GR+ +L L L IEL+K
Sbjct 286 ALFAKNKKTNEIKKTTSEIVLICIGRKANFDNLNLHLLNIELNK 329
> eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydrogenase,
E3 component is part of three enzyme complexes (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=474
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 39/112 (34%), Positives = 63/112 (56%), Gaps = 4/112 (3%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
+IGLE+G+V+ +G+++ VVE D++IPA D +I + F K + ++ M TKV +
Sbjct 185 IIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKK-FNLMLETKVTAVEA 243
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ VT+E K D VLVA+GR P ++L + G+E+D R
Sbjct 244 KEDGIYVTME---GKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDR 292
> pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=666
Score = 67.8 bits (164), Expect = 9e-12, Method: Composition-based stats.
Identities = 34/121 (28%), Positives = 71/121 (58%), Gaps = 10/121 (8%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKL-LERQGIKFMFSTKVVGSQ 59
+IGLE ++ +G+E+T +E+ +++P +D ++ + F+++ L+ + + + +T+V +
Sbjct 331 IIGLEFADIYTALGSEITFLEYSSELLPIIDNDVAKYFERVFLKNKPVNYHLNTEVKYIK 390
Query 60 KSNENDEVTL---------ELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELD 110
S N+ V + + E D +L+ D LVA GR P T++LGLE+L I+++
Sbjct 391 ASKNNNPVIIGYSHRTGNDDNEKKNMTDVKELYVDSCLVATGRNPNTQNLGLEKLKIQMN 450
Query 111 K 111
+
Sbjct 451 R 451
> ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=630
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 41/115 (35%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLE V+ +G+EVT +E D+++P D EI + Q++L K + T V S+ +
Sbjct 325 IGLEFSDVYTALGSEVTFIEALDQLMPGFDPEISKLAQRVLINTR-KIDYHTGVFASKIT 383
Query 62 NEND--EVTLELENAKS---GDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
D V +EL +AK+ DTL++ D L+A GR P+T LGLE + + +
Sbjct 384 PAKDGKPVLIELIDAKTKEPKDTLEV--DAALIATGRAPFTNGLGLENINVTTQR 436
> ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrolipoyl
dehydrogenase; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=623
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 8/111 (7%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
IGLE V+ +G+EVT +E D+++P D EI + Q++L K + T V S+ +
Sbjct 265 IGLEFSDVYTALGSEVTFIEALDQLMPGFDPEISKLAQRVLINPR-KIDYHTGVFASKIT 323
Query 62 NEND--EVTLELENAKS---GDTLKLHCDVVLVAVGRRPYTRDLGLEELGI 107
D V +EL +AK+ DTL++ D L+A GR P+T LGLE + +
Sbjct 324 PARDGKPVLIELIDAKTKEPKDTLEV--DAALIATGRAPFTNGLGLENVNV 372
> tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putative
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=636
Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats.
Identities = 37/117 (31%), Positives = 67/117 (57%), Gaps = 7/117 (5%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQ----GIKFMFSTKVVG 57
IGLE V+ ++G+EV +VE +++P +D E+ + ++LL +Q +K +T
Sbjct 330 IGLEFMDVFTSLGSEVVMVEAGPRLLPGVDKEVAKLAERLLLQQFKERPVKLYTNTLASQ 389
Query 58 SQKSNENDE--VTLELENAKSGDTL-KLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
+ E V ++L +A++ ++ K++ D L+A GRRP T LGL+ LG+ L +
Sbjct 390 VRPLGPKGEAPVEVQLTDAQTKESKGKIYPDACLIATGRRPNTEGLGLDSLGVTLKR 446
> dre:100332932 glutathione reductase-like
Length=461
Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/109 (28%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +E +++ +G E T++ +I+ D ++ R + +GI+ + + + +Q S
Sbjct 181 IAVEFANIFHGLGVETTLIYRGKEILSRFDGDLRRGLHNAMTAKGIRII--CQDIMTQVS 238
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELD 110
+ + + E K G+TL++ D V++A+GR P+TR LGLE G+ D
Sbjct 239 RDGEGLVAE---TKEGETLRV--DTVMLALGRDPHTRGLGLEAAGVATD 282
> ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase);
FAD binding / NADP or NADPH binding / glutathione-disulfide
reductase/ oxidoreductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=499
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIP--ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
I +E S+WR MGA V + F K +P D E+ + LE +G+ T +
Sbjct 214 IAVEFASIWRGMGATVDL--FFRKELPLRGFDDEMRALVARNLEGRGVNLHPQTSLTQLT 271
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
K+++ +V S + DVVL A GR P T+ L LE +G+ELD+
Sbjct 272 KTDQGIKVI-------SSHGEEFVADVVLFATGRSPNTKRLNLEAVGVELDQ 316
> cel:F20D6.11 hypothetical protein
Length=549
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 7/112 (6%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
IG+E+ S A VTV+ + +P +IG+ + E +G+KF + VV +
Sbjct 292 FIGMEVASALAEKAASVTVISNTPEPLPVFGSDIGKGIRLKFEEKGVKFELAANVVALRG 351
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+++ + + LEN K +L D+++ +G P T+ LE GI+LD R
Sbjct 352 NDQGEVSKVILENGK-----ELDVDLLVCGIGVTPATK--FLEGSGIKLDNR 396
> eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide-disulfide
oxidoreductase
Length=441
Score = 50.4 bits (119), Expect = 1e-06, Method: Composition-based stats.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 8/109 (7%)
Query 4 LELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKSNE 63
+E S++ N G++VT++E +P D +I +L QG+ + + V + S+
Sbjct 171 VEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIILNAHV--ERISHH 228
Query 64 NDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
++V + E+A +L D +L+A GR+P T L E GI +++R
Sbjct 229 ENQVQVHSEHA------QLAVDALLIASGRQPATASLHPENAGIAVNER 271
> hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=522
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 6/115 (5%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +E+ + +G++ +++ DK++ + D I + LE G++ + ++V +K+
Sbjct 242 IAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKT 301
Query 62 NENDEVTLELENAKSGD----TLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
EV++ A G T+ D +L A+GR P T+DL L +LGI+ D +
Sbjct 302 LSGLEVSMV--TAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDK 354
> mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione
reductase (EC:1.8.1.7); K00383 glutathione reductase (NADPH)
[EC:1.8.1.7]
Length=500
Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats.
Identities = 28/113 (24%), Positives = 58/113 (51%), Gaps = 2/113 (1%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +E+ + +G++ +++ DK++ D I + LE G++ + T+V +K+
Sbjct 220 IAVEIAGILSALGSKTSLMIRHDKVLRNFDSLISSNCTEELENAGVEVLKFTQVKEVKKT 279
Query 62 NENDE--VTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ E V + K T+ D +L A+GR P ++ L L ++GI+ D++
Sbjct 280 SSGLELQVVTSVPGRKPTTTMIPDVDCLLWAIGRDPNSKGLNLNKVGIQTDEK 332
> mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase
3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=652
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 29/113 (25%), Positives = 62/113 (54%), Gaps = 3/113 (2%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGSQ 59
+GLE +G +VTV+ ++ D E+ LE+QG+KF F+ +V
Sbjct 354 VGLECAGFLAGLGLDVTVM-VRSVLLRGFDQEMAEKVGSYLEQQGVKFQRKFTPILVQQL 412
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ ++ + ++ + +T++ + VL+A+GR TR +GLE++G++++++
Sbjct 413 EKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVKINEK 465
> eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotide
transhydrogenase, soluble (EC:1.6.1.1); K00322 NAD(P) transhydrogenase
[EC:1.6.1.1]
Length=466
Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats.
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
+IG E S++R M +V ++ D+++ LD E+ + G+ + + +
Sbjct 186 VIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEY--EKI 243
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+D V + L++ K KL D +L A GR T L L+ +G+E D R
Sbjct 244 EGCDDGVIMHLKSGK-----KLKADCLLYANGRTGNTDSLALQNIGLETDSR 290
> dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=425
Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
I +E+ + +G++ +++ ++ D I K L+ GI +T+V +K
Sbjct 185 YIAVEMAGILSTLGSKTSIIIRQGGVLRNFDALISSNCTKELQNNGIDLRKNTQVKSVKK 244
Query 61 SNENDEVTLELENAKSGDTLKLH-----CDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ + +TL ++ D+ + D +L A+GR P T L L ++G++LD+R
Sbjct 245 NGKGLSITLVTKDPDDKDSQEKFDTINDVDCLLWAIGREPNTAGLNLSQIGVKLDER 301
> sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathione
oxidoreductase, converts oxidized glutathione to reduced
glutathione; mitochondrial but not cytosolic form has a role
in resistance to hyperoxia (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 5/112 (4%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
IG+EL V+ +G+E +V + ++ D I ++GI +K+V +K
Sbjct 207 YIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEK 266
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ E D++ + + ++KS D + D ++ +GR+ + +G E +GI+L+
Sbjct 267 NVETDKLKIHMNDSKSIDDV----DELIWTIGRKSHL-GMGSENVGIKLNSH 313
> mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=499
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 27/114 (23%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGS 58
+ LE +G +VTV+ ++ D ++ + +E GIKF+ F +
Sbjct 200 YVALECAGFLAGIGLDVTVM-VRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQ 258
Query 59 QKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
++ + + ++ S +T++ + VL+AVGR TR +GLE +G++++++
Sbjct 259 IEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEK 312
> hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3
(EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=607
Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 59/113 (52%), Gaps = 3/113 (2%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGSQ 59
+ LE G +VTV+ ++ D E+ +E+ G+KF+ F +V
Sbjct 345 VALECAGFLAGFGLDVTVM-VRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQL 403
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ ++ + ++ + +T++ + VL+A+GR TR +GLE++G++++++
Sbjct 404 EKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEK 456
> tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7)
Length=505
Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats.
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 26/131 (19%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFS--------- 52
+ ELG + R++G +V++ + + D E + + GI+
Sbjct 175 VSAELGGILRHLGVDVSIFMRNQRQLKRFDKEAVESLEATQRASGIQLYKGVNAVEISIS 234
Query 53 ----TKVVGSQKSNENDEVTLELENAKSGDTLKLHCDV---------VLVAVGRRPYTRD 99
TK+ S ++ E + LE++ L +H D V++AV P D
Sbjct 235 KADGTKLSASYTFHDQTETSYHLEDS----LLTVHLDNGDAHHGFDHVIMAVNPAPAIED 290
Query 100 LGLEELGIELD 110
LGLEE G+++D
Sbjct 291 LGLEEAGVDID 301
> ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding /
glutathione-disulfide reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=565
Score = 36.6 bits (83), Expect = 0.018, Method: Composition-based stats.
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I LE ++ + EV V K++ D ++ + + +GI+F K+
Sbjct 271 IALEFAGIFNGLNCEVHVFIRQKKVLRGFDEDVRDFVGEQMSLRGIEFHTEESPEAIIKA 330
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDK 111
+ + L+ +K H V+ A GR+P T++LGLE +G+++ K
Sbjct 331 GDG---SFSLKTSKGTVEGFSH---VMFATGRKPNTKNLGLENVGVKMAK 374
> tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 36.2 bits (82), Expect = 0.025, Method: Composition-based stats.
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +E V+ M E + ++ + D I + + + G++ + V + +
Sbjct 200 IAVEFAGVFAAMKCETHLFVRHERALRKFDDMISMRVDEFMRKAGVQ-IHPHSVAKAVRQ 258
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIE 108
+ +TLEL N +S D V+V+VGR P +LGL+ +G++
Sbjct 259 EADKSLTLELTNGESFRGF----DSVIVSVGRVPEVANLGLDVVGVK 301
> tgo:TGME49_007620 pyridine nucleotide-disulphide oxidoreductase
domain-containing protein (EC:1.7.1.4 1.18.1.3)
Length=664
Score = 35.8 bits (81), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 14/106 (13%)
Query 1 LIGLELGSVWRNMGAE-VTVVEFCDKIIP---ALDVEIGRAFQKLLERQGIKFMFSTKVV 56
+G+EL + + G + VTV+ + +P L +G + ++L+ +G++F +KVV
Sbjct 391 FVGVELAAAFHRRGCKNVTVIG--QETVPFERVLGSRVGGSIKQLICSKGVRFYPQSKVV 448
Query 57 GSQKSNENDEVT-LELENAKSGDTLKLHCDVVLVAVGRRPYTRDLG 101
G S D VT +EL SG+ ++ DVV+V +G P T+ L
Sbjct 449 GFTSS--RDRVTGVEL---ASGEIIQ--ADVVIVGIGSVPATKFLA 487
> ath:AT3G52880 ATMDAR1; monodehydroascorbate reductase, putative;
K08232 monodehydroascorbate reductase (NADH) [EC:1.6.5.4]
Length=466
Score = 35.8 bits (81), Expect = 0.036, Method: Composition-based stats.
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPAL-DVEIGRAFQKLLERQGIKFMFSTKVVG--S 58
IGLEL +V R +VT+V +P L +I ++ +G+K + T G +
Sbjct 206 IGLELSAVLRINNLDVTMVFPEPWCMPRLFTADIAAFYETYYTNKGVKIIKGTVASGFTA 265
Query 59 QKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYT 97
Q + E EV L K G TL+ D+V+V VG +P T
Sbjct 266 QPNGEVKEVQL-----KDGRTLE--ADIVIVGVGAKPLT 297
> xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=596
Score = 35.8 bits (81), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 26/114 (22%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGS 58
+ LE +G + TV+ + D E+ +E G+KF+ F V
Sbjct 299 YVALECAGFLAGIGLDATVM-VRSIFLRGFDQEMANRAGAYMETHGVKFIKQFVPIKVEL 357
Query 59 QKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ + + ++ + ++ + VL+AVGR TR++GLE++G+++++R
Sbjct 358 LEEGTPGRIKVTAKSTQGDQIIEDEYNTVLIAVGRDACTRNIGLEKIGVKINER 411
> eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreductase
(EC:1.8.1.7); K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=450
Score = 35.4 bits (80), Expect = 0.039, Method: Composition-based stats.
Identities = 28/113 (24%), Positives = 58/113 (51%), Gaps = 10/113 (8%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIP--ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
I +EL V +GA+ + F K P + D I +++ +G + + + + +
Sbjct 178 IAVELAGVINGLGAKTHL--FVRKHAPLRSFDPMISETLVEVMNAEGPQ-LHTNAIPKAV 234
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
N + +TLELE+ +S +T+ D ++ A+GR P ++ LE G++ +++
Sbjct 235 VKNTDGSLTLELEDGRS-ETV----DCLIWAIGREPANDNINLEAAGVKTNEK 282
> tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=662
Score = 35.4 bits (80), Expect = 0.039, Method: Composition-based stats.
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I LE R +G +VTV ++ D + LE G++ + T +
Sbjct 349 ISLECAGFLRELGFDVTVA-VRSILLRGFDRQCAEQVGLCLEEAGVRILRET-IPAKMVK 406
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIE 108
N ++ + + K L D VL A GR+ T +L L+ G+E
Sbjct 407 QANGKIQVTFQVGKEKKELVEEFDTVLYATGRKADTSNLNLQAAGVE 453
> cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=526
Score = 35.4 bits (80), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 12/111 (10%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIP--ALDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
IGLE +G + TV + IP D + + ++ G KF+ + +
Sbjct 220 IGLETAGFLNELGFDTTV---AMRSIPLRGFDRQCSEKIVEYMKATGTKFLVGVVPINIE 276
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELD 110
K NEN +V+ + + +T VL A GR P + L L +G+E+
Sbjct 277 KVNENIKVSFSDGSVEEFET-------VLYATGRNPDVKGLNLNAIGVEVS 320
> pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=500
Score = 35.0 bits (79), Expect = 0.052, Method: Composition-based stats.
Identities = 25/109 (22%), Positives = 55/109 (50%), Gaps = 5/109 (4%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +EL +V + +G + + ++I+ D + + +++ I + VV +K
Sbjct 187 IAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADVVEIKKV 246
Query 62 NENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELD 110
++ + +++ L + + + H D V+ VGR P T +L LE+L +E +
Sbjct 247 SDKN-LSIHLSDGR----IYEHFDHVIYCVGRSPDTENLNLEKLNVETN 290
> tpv:TP03_0672 oxidoreductase
Length=597
Score = 35.0 bits (79), Expect = 0.064, Method: Composition-based stats.
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 17/107 (15%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPAL-DVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
IG EL SV ++ GA VTV+ + + + +G KL+E+ G+KF+ +
Sbjct 347 FIGCELSSVLKSTGANVTVLTNTETPLETIVGKRVGGVVAKLMEKNGVKFLPKCTI---- 402
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELG 106
+EV L+ + L D V+ VG R T L +L
Sbjct 403 -----NEVVLD-------NNTTLKADAVIEGVGTRVDTSLLPCAQLA 437
> ath:AT5G03630 ATMDAR2; monodehydroascorbate reductase (NADH);
K08232 monodehydroascorbate reductase (NADH) [EC:1.6.5.4]
Length=435
Score = 34.7 bits (78), Expect = 0.068, Method: Composition-based stats.
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPAL-DVEIGRAFQKLLERQGIKFMFSTKVVGSQK 60
IGLELG+ + +VT+V +P L I ++ +GI + T V
Sbjct 175 IGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGT-VASGFT 233
Query 61 SNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRP 95
+N N EVT K D L D+V+V VG RP
Sbjct 234 TNSNGEVT----EVKLKDGRTLEADIVIVGVGGRP 264
> dre:100150876 apoptosis-inducing factor, mitochondrion-associated,
3
Length=599
Score = 34.7 bits (78), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP---ALDVEIGRAFQKLLERQGIKFMFSTKVVG 57
IG+E+ + + V+V+ + +P AL ++G+A KL E +KF +V
Sbjct 342 FIGMEVAAALTDKAHSVSVIGI--EAVPFRKALGEKVGKALMKLFESNRVKFYMLNEVWE 399
Query 58 SQKSN-ENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
+ N + EV L KSG L+ DV ++ +G P T L++ G+ +D +
Sbjct 400 MRGHNGQLKEVVL-----KSGKVLR--ADVCVIGIGSSPAT--AFLKQSGVHIDSK 446
> dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=602
Score = 34.7 bits (78), Expect = 0.087, Method: Compositional matrix adjust.
Identities = 23/114 (20%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGS 58
+ LE G +G +VT++ ++ D ++ + +E G+KF+ F +
Sbjct 303 YVALECGGFLAGLGLDVTIM-VRSILLRGFDQDMADRAGEYMETHGVKFLRKFVPTKIEQ 361
Query 59 QKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
++ + + ++ +S + + + VL+AVGR T +GL++ G++++++
Sbjct 362 LEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEK 415
> hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=649
Score = 34.3 bits (77), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 25/114 (21%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM--FSTKVVGS 58
+ LE +G +VTV+ ++ D ++ + +E GIKF+ F V
Sbjct 350 YVALECAGFLAGIGLDVTVM-VRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQ 408
Query 59 QKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
++ + + ++ S + ++ + V++A+GR TR +GLE +G++++++
Sbjct 409 IEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEK 462
> cel:C46F11.2 hypothetical protein
Length=473
Score = 32.3 bits (72), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 16/116 (13%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKS 61
I +E+ V N+G++ ++ DK++ R F K+L + M +
Sbjct 193 IAVEIAGVLANLGSDTHLLIRYDKVL--------RTFDKMLSDELTADM--DEETNPLHL 242
Query 62 NENDEVTLELENAKSGDTLKLHCDVV------LVAVGRRPYTRDLGLEELGIELDK 111
++N +VT ++ T+K V+ + A+GR P T++L LE +G++ DK
Sbjct 243 HKNTQVTEVIKGDDGLLTIKTTTGVIEKVQTLIWAIGRDPLTKELNLERVGVKTDK 298
> mmu:72168 Aifm3, 2810401C16Rik, AI840249, Aifl; apoptosis-inducing
factor, mitochondrion-associated 3
Length=598
Score = 31.6 bits (70), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 9/113 (7%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIPA-LDVEIGRAFQKLLERQGIKFMFSTKVVGSQ 59
+G+E+ + V+VVE + L +GRA K+ E +KF T+ V
Sbjct 342 FLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTE-VSEL 400
Query 60 KSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
++ E + L+++K L DV ++ +G P T L + GI LD R
Sbjct 401 RAQEGKLQEVVLKSSKV-----LRADVCVLGIGAVPATGF--LRQSGIGLDSR 446
> xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=531
Score = 31.2 bits (69), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query 2 IGLELGSVWRNMGAEVTVVEFCDKIIPALDVEIGRAFQKLLERQGIKFM---FSTKVVGS 58
+ LE +G +VTV+ ++ D ++ + +E G+KF+ TK+
Sbjct 236 VALECAGFLAGLGLDVTVM-VRSILLRGFDQQMANKIGEYMEEHGVKFIRQFVPTKI--- 291
Query 59 QKSNENDEVTLE-----LENAKSGDTLKLHCDVVLVAVGRRPYTRDLGLEELGIELDKR 112
E E + A G + VL+A+GR TR++GLE G++++++
Sbjct 292 ----EQIEAGMPGRLKVTSQAPDGTETTDEYNTVLLAIGRDACTRNIGLEIPGVKINEK 346
> dre:557064 apoptosis-inducing factor, mitochondrion-associated,
3-like
Length=573
Score = 31.2 bits (69), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query 1 LIGLELGSVWRNMGAEVTVVEFCDKIIP---ALDVEIGRAFQKLLERQGIKFMFSTKVVG 57
IG+E+ + + + +TV+ + +P L EIG+ +LE +G+ F + V
Sbjct 317 FIGMEVAAYLLDTSSSMTVIGSSE--LPYQKTLGREIGKVTMTMLEEKGVTFYMNDAVAE 374
Query 58 SQKSNENDEVTLELENAKSGDTLKLHCDVVLVAVGRRP 95
Q N ++ KSG T++ D+++VA+G P
Sbjct 375 VQGKNRR----VKAVKLKSGITIE--ADLLIVAIGVSP 406
> dre:555791 MGC162952; zgc:162952
Length=313
Score = 31.2 bits (69), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 1/89 (1%)
Query 24 DKIIPALDVEIGRAFQKLLERQGIKFMFSTKVVGSQKSNENDEVTLELENAKSGDTLKLH 83
DK+ P L+ G ++LL RQ + + KV + + L +N D +
Sbjct 110 DKLYPILEYVSGGCLEELLARQDVPLCWREKVDLASDITRG-MIYLHYKNIYHRDLNSKN 168
Query 84 CDVVLVAVGRRPYTRDLGLEELGIELDKR 112
C + + A GR D GL +EL +
Sbjct 169 CLIRMTARGREALVTDFGLAREVVELPSK 197
Lambda K H
0.319 0.139 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2057481480
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40