bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_2057_orf3
Length=70
Score E
Sequences producing significant alignments: (Bits) Value
pfa:MAL13P1.301 gc-betA; guanylyl cyclase (EC:4.6.1.2); K01769... 97.8 8e-21
pfa:PF11_0395 guanylyl cyclase; K01769 guanylate cyclase, othe... 93.6 1e-19
tgo:TGME49_054370 adenylate and guanylate cyclase catalytic do... 92.4 3e-19
tpv:TP02_0848 guanylyl cyclase 91.7 5e-19
bbo:BBOV_I000770 16.m00775; adenylate and guanylate cyclase ca... 84.3 9e-17
cpv:cgd3_1110 P-type ATpase fused to two adenyl cyclase domain... 77.8 8e-15
mmu:104111 Adcy3, AC3, mKIAA0511; adenylate cyclase 3 (EC:4.6.... 65.5 4e-11
hsa:109 ADCY3, AC3, KIAA0511; adenylate cyclase 3 (EC:4.6.1.1)... 65.5 4e-11
dre:564719 adcy3, si:ch211-153j24.5; adenylate cyclase 3; K080... 64.3 9e-11
dre:100148976 adcy8, si:ch211-220f13.4; adenylate cyclase 8 (b... 59.3 3e-09
mmu:11514 Adcy8, AC8, AW060868; adenylate cyclase 8 (EC:4.6.1.... 58.9 3e-09
hsa:114 ADCY8, AC8, ADCY3, HBAC1; adenylate cyclase 8 (brain) ... 58.9 3e-09
cel:C10F3.3 acy-2; Adenylyl CYclase family member (acy-2) 58.5 5e-09
dre:557026 adcy1a, si:dkey-162m2.1; adenylate cyclase 1a (EC:4... 57.8 8e-09
dre:100333979 adenylate cyclase 1a-like 57.8 8e-09
mmu:104110 Adcy4, KIAA4004, mKIAA4004; adenylate cyclase 4 (EC... 57.4 1e-08
hsa:196883 ADCY4, AC4; adenylate cyclase 4 (EC:4.6.1.1); K0804... 57.4 1e-08
hsa:107 ADCY1, AC1; adenylate cyclase 1 (brain) (EC:4.6.1.1); ... 57.0 1e-08
mmu:432530 Adcy1, AC1, D11Bwg1392e, I-AC, KIAA4070, brl, mKIAA... 57.0 1e-08
dre:569499 adcy1b; adenylate cyclase 1b (EC:4.6.1.1); K08041 a... 57.0 1e-08
dre:568726 adcy7, ADCY4a; adenylate cyclase 7 (EC:4.6.1.1); K0... 56.2 2e-08
hsa:113 ADCY7, AC7, FLJ36387, KIAA0037; adenylate cyclase 7 (E... 56.2 2e-08
dre:557902 adcy2b, si:dkey-266i6.1; adenylate cyclase 2b (brai... 55.8 3e-08
mmu:210044 Adcy2, MGC47193, mKIAA1060; adenylate cyclase 2 (EC... 55.8 3e-08
hsa:108 ADCY2, AC2, FLJ16822, FLJ45092, HBAC2, KIAA1060, MGC13... 55.8 3e-08
dre:560719 si:dkey-206f10.1; K08048 adenylate cyclase 8 [EC:4.... 55.8 3e-08
dre:560410 adenylate cyclase 8-like; K08048 adenylate cyclase ... 55.1 5e-08
dre:563724 adcy2a; adenylate cyclase 2a; K08042 adenylate cycl... 54.7 7e-08
cel:T01C2.1 acy-4; Adenylyl CYclase family member (acy-4) 54.7 8e-08
mmu:11513 Adcy7, AA407758, MGC141539; adenylate cyclase 7 (EC:... 54.7 8e-08
cel:F17C8.1 acy-1; Adenylyl CYclase family member (acy-1); K08... 53.1 2e-07
dre:560807 adcy6b, si:ch211-190a18.1; adenylate cyclase 6b; K0... 52.4 3e-07
hsa:111 ADCY5, AC5; adenylate cyclase 5 (EC:4.6.1.1); K08045 a... 52.4 3e-07
mmu:224129 Adcy5, AW121902, Ac5; adenylate cyclase 5 (EC:4.6.1... 52.4 4e-07
dre:570652 adcy6a, adcy6; adenylate cyclase 6a; K08046 adenyla... 52.0 4e-07
mmu:11512 Adcy6, mKIAA0422; adenylate cyclase 6 (EC:4.6.1.1); ... 51.6 7e-07
hsa:112 ADCY6, AC6, DKFZp779F075, KIAA0422; adenylate cyclase ... 51.6 7e-07
mmu:11515 Adcy9, ACtp10, AW125421, D16Wsu65e, mKIAA0520; adeny... 51.6 7e-07
hsa:115 ADCY9, AC9, FLJ12046; adenylate cyclase 9 (EC:4.6.1.1)... 51.6 7e-07
xla:378610 adcy9, xlAC; adenylate cyclase 9 (EC:4.6.1.1); K080... 51.2 7e-07
dre:562619 adcy5; adenylate cyclase 5 (EC:4.6.1.1); K08045 ade... 51.2 8e-07
dre:100332957 adenylate cyclase type 5-like 50.8 9e-07
cel:T01A4.1 gcy-28; Guanylyl CYclase family member (gcy-28); K... 50.1 2e-06
dre:100333538 adenylyl cyclase 35C-like 49.7 2e-06
cel:F23H12.6 gcy-13; Guanylyl CYclase family member (gcy-13); ... 49.7 2e-06
dre:571825 adcy3l; adenylate cyclase 3-like; K08043 adenylate ... 49.3 3e-06
cel:M04G12.3 gcy-34; Guanylyl CYclase family member (gcy-34); ... 49.3 3e-06
cel:F22E5.3 gcy-21; Guanylyl CYclase family member (gcy-21); K... 48.5 5e-06
cel:T03D8.5 gcy-22; Guanylyl CYclase family member (gcy-22); K... 48.1 6e-06
cel:F21H7.9 gcy-20; Guanylyl CYclase family member (gcy-20); K... 48.1 6e-06
> pfa:MAL13P1.301 gc-betA; guanylyl cyclase (EC:4.6.1.2); K01769
guanylate cyclase, other [EC:4.6.1.2]
Length=3179
Score = 97.8 bits (242), Expect = 8e-21, Method: Composition-based stats.
Identities = 40/60 (66%), Positives = 50/60 (83%), Gaps = 0/60 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREE 62
NMRIGLH GSCVGG+IGS R+RYD+WGLDVL+ N IESNG+PG+I CS++F+ F + E
Sbjct 3065 FNMRIGLHYGSCVGGIIGSVRIRYDMWGLDVLIANKIESNGIPGEIICSEQFRHFFIQNE 3124
Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 0/49 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCS 51
++++IG+H G + GVIGS + +Y L+G V + ++S +P I S
Sbjct 1663 ISLKIGIHTGKAISGVIGSVKPQYALFGDTVNTASRMKSTSLPDHIHVS 1711
> pfa:PF11_0395 guanylyl cyclase; K01769 guanylate cyclase, other
[EC:4.6.1.2]
Length=4226
Score = 93.6 bits (231), Expect = 1e-19, Method: Composition-based stats.
Identities = 41/55 (74%), Positives = 46/55 (83%), Gaps = 0/55 (0%)
Query 1 PGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFK 55
P LNMRIGLH GSCVGGVIGS RLRYDLWG+DVL GN +ESNG+PG+I S+ K
Sbjct 4065 PNLNMRIGLHYGSCVGGVIGSGRLRYDLWGIDVLTGNLMESNGIPGKINVSETLK 4119
Score = 36.2 bits (82), Expect = 0.028, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 31/50 (62%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+ +++G+H G + GV+GS++ +Y L+G V + +++ G P I S+
Sbjct 3233 IRVKVGIHSGRIIAGVVGSKKPQYALFGDTVNTASRMKTTGKPDYIHISE 3282
> tgo:TGME49_054370 adenylate and guanylate cyclase catalytic
domain-containing protein (EC:4.6.1.1 3.6.3.1 1.15.1.1 4.6.1.2
3.1.3.48 2.8.3.8)
Length=4368
Score = 92.4 bits (228), Expect = 3e-19, Method: Composition-based stats.
Identities = 42/60 (70%), Positives = 48/60 (80%), Gaps = 0/60 (0%)
Query 1 PGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQR 60
P LNMRIGLH GSCVGGVIGS RLRYDLWG+DVL GN +ESNGVPG+I S+ K ++
Sbjct 4121 PNLNMRIGLHYGSCVGGVIGSGRLRYDLWGMDVLTGNMMESNGVPGKINVSEILKNEMEK 4180
Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats.
Identities = 16/51 (31%), Positives = 33/51 (64%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+ ++IG+H G + GV+G+++ +Y L+G V + +++ G PG I S++
Sbjct 3115 IRVKIGIHSGRVISGVVGAKKPQYALFGDTVNTASRMKTTGQPGYIHISED 3165
> tpv:TP02_0848 guanylyl cyclase
Length=2664
Score = 91.7 bits (226), Expect = 5e-19, Method: Composition-based stats.
Identities = 38/55 (69%), Positives = 45/55 (81%), Gaps = 0/55 (0%)
Query 1 PGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFK 55
P L MRIGLH GSC+GGVIGS RLRYD+WG DV N IESNGVPG++C S++F+
Sbjct 2555 PDLKMRIGLHYGSCIGGVIGSGRLRYDVWGTDVYTANMIESNGVPGEVCVSEKFR 2609
Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats.
Identities = 14/50 (28%), Positives = 31/50 (62%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+ ++IG++ G + G++GS++ +Y L+G V + ++ G G+I S+
Sbjct 1840 IGVKIGINSGYVISGLVGSKKPQYALFGDTVNTASRMKMTGEVGRIHISE 1889
> bbo:BBOV_I000770 16.m00775; adenylate and guanylate cyclase
catalytic domain containing protein
Length=2446
Score = 84.3 bits (207), Expect = 9e-17, Method: Composition-based stats.
Identities = 36/56 (64%), Positives = 44/56 (78%), Gaps = 0/56 (0%)
Query 1 PGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKI 56
PGLNMRIGLH G VGGVIGS RLRYDLWG+D+ N +ES+G+PG+I S+ K+
Sbjct 2351 PGLNMRIGLHYGHAVGGVIGSGRLRYDLWGMDIHTANAMESHGIPGKINISERLKL 2406
Score = 28.1 bits (61), Expect = 7.1, Method: Composition-based stats.
Identities = 11/44 (25%), Positives = 27/44 (61%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+++G++ G + G++G ++ +Y L+G V + +++ G G I
Sbjct 1705 VKVGINSGKIISGLVGFKKPQYALFGDTVNTASRMKTTGESGYI 1748
> cpv:cgd3_1110 P-type ATpase fused to two adenyl cyclase domains
and 21 predicted transmembrane regions
Length=3848
Score = 77.8 bits (190), Expect = 8e-15, Method: Composition-based stats.
Identities = 31/54 (57%), Positives = 41/54 (75%), Gaps = 0/54 (0%)
Query 1 PGLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEF 54
P L+MRIGLH G C+GG++GS RLRY++WG DV++GN +ES G PG I S +
Sbjct 3726 PELSMRIGLHYGGCIGGIVGSSRLRYEVWGHDVIIGNRMESCGTPGNITISGQL 3779
Score = 34.3 bits (77), Expect = 0.086, Method: Composition-based stats.
Identities = 16/49 (32%), Positives = 30/49 (61%), Gaps = 0/49 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCS 51
L ++IG+H G + GV+G+ + +Y L+G V + ++S+ G+I S
Sbjct 2865 LKLKIGIHSGRVISGVVGTNKPQYALFGDTVNTASRMKSSCETGKIQVS 2913
> mmu:104111 Adcy3, AC3, mKIAA0511; adenylate cyclase 3 (EC:4.6.1.1);
K08043 adenylate cyclase 3 [EC:4.6.1.1]
Length=1144
Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats.
Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 0/65 (0%)
Query 2 GLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQRE 61
G++MR+G+H G+ +GGV+G +R +YD+W DV V N +E+ G+PG++ S+ + E
Sbjct 408 GVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGE 467
Query 62 EHSEP 66
EP
Sbjct 468 FDVEP 472
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 0/52 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKI 56
+RIG++ G + GVIG+R+ YD+WG V V + +ES GV G I +E ++
Sbjct 1040 LRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQV 1091
> hsa:109 ADCY3, AC3, KIAA0511; adenylate cyclase 3 (EC:4.6.1.1);
K08043 adenylate cyclase 3 [EC:4.6.1.1]
Length=1144
Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats.
Identities = 26/65 (40%), Positives = 43/65 (66%), Gaps = 0/65 (0%)
Query 2 GLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQRE 61
G++MR+G+H G+ +GGV+G +R +YD+W DV V N +E+ G+PG++ S+ + E
Sbjct 408 GVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGE 467
Query 62 EHSEP 66
EP
Sbjct 468 FDVEP 472
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/52 (42%), Positives = 34/52 (65%), Gaps = 0/52 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKI 56
+RIG++ G + GVIG+R+ YD+WG V V + +ES GV G I +E ++
Sbjct 1040 LRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQV 1091
> dre:564719 adcy3, si:ch211-153j24.5; adenylate cyclase 3; K08043
adenylate cyclase 3 [EC:4.6.1.1]
Length=1071
Score = 64.3 bits (155), Expect = 9e-11, Method: Composition-based stats.
Identities = 25/60 (41%), Positives = 41/60 (68%), Gaps = 0/60 (0%)
Query 2 GLNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQRE 61
G++MR+G+H G+ +GGV+G +R ++D+W DV V N +ES G+PG++ S+ K E
Sbjct 396 GVDMRVGVHSGTVLGGVLGQKRWQFDVWSTDVTVANKMESGGIPGRVHISQSTKDCLHDE 455
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/44 (50%), Positives = 31/44 (70%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+RIGL+ GS + GVIG+R+ +D+WG V V + +ES GV G I
Sbjct 970 LRIGLNKGSVLAGVIGARKPHFDIWGNTVNVASRMESTGVMGNI 1013
> dre:100148976 adcy8, si:ch211-220f13.4; adenylate cyclase 8
(brain) (EC:4.6.1.1); K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1225
Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats.
Identities = 24/50 (48%), Positives = 37/50 (74%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG+I SK
Sbjct 478 IDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISK 527
Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 21/51 (41%), Positives = 34/51 (66%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+RIG+ GS V GVIG+++ +YD+WG V + + ++S GV G+I +E
Sbjct 1060 FQLRIGMAHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGKIQLPEE 1110
> mmu:11514 Adcy8, AC8, AW060868; adenylate cyclase 8 (EC:4.6.1.1);
K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1249
Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats.
Identities = 24/50 (48%), Positives = 37/50 (74%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG+I SK
Sbjct 502 VDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISK 551
Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats.
Identities = 21/51 (41%), Positives = 34/51 (66%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+RIG+ GS V GVIG+++ +YD+WG V + + ++S GV G+I +E
Sbjct 1083 FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEE 1133
> hsa:114 ADCY8, AC8, ADCY3, HBAC1; adenylate cyclase 8 (brain)
(EC:4.6.1.1); K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1251
Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats.
Identities = 24/50 (48%), Positives = 37/50 (74%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
++MRIG+H GS + GV+G R+ ++D+W DV + N +ES G+PG+I SK
Sbjct 504 VDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISK 553
Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats.
Identities = 21/51 (41%), Positives = 34/51 (66%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+RIG+ GS V GVIG+++ +YD+WG V + + ++S GV G+I +E
Sbjct 1085 FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEE 1135
> cel:C10F3.3 acy-2; Adenylyl CYclase family member (acy-2)
Length=1080
Score = 58.5 bits (140), Expect = 5e-09, Method: Composition-based stats.
Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 0/53 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFK 55
+NMRIG+H GS + G++G R+ ++D+W DV + N +ES GVPG + +K K
Sbjct 404 VNMRIGVHTGSVLCGIMGLRKWQFDIWSDDVTLANHMESAGVPGAVHITKSTK 456
Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 32/46 (69%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+RIG+ VG V GVIG+++ +YD+WG V + + ++++G P +I
Sbjct 971 FELRIGMSVGPLVAGVIGAQKPQYDIWGNTVNLASRMDTHGEPRKI 1016
> dre:557026 adcy1a, si:dkey-162m2.1; adenylate cyclase 1a (EC:4.6.1.1);
K08041 adenylate cyclase 1 [EC:4.6.1.1]
Length=1114
Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats.
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 10/72 (13%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI--------CCSKEF 54
LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ G+PG++ C + ++
Sbjct 386 LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITKATLECLNGDY 445
Query 55 KIS--FQREEHS 64
++ F E H+
Sbjct 446 EVEPGFGHERHA 457
Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats.
Identities = 22/44 (50%), Positives = 33/44 (75%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+R+G++VG V GVIG+RR +YD+WG V V + ++S GV G+I
Sbjct 968 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKI 1011
> dre:100333979 adenylate cyclase 1a-like
Length=829
Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats.
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 10/72 (13%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI--------CCSKEF 54
LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ G+PG++ C + ++
Sbjct 133 LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITKATLECLNGDY 192
Query 55 KIS--FQREEHS 64
++ F E H+
Sbjct 193 EVEPGFGHERHA 204
Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats.
Identities = 22/44 (50%), Positives = 33/44 (75%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+R+G++VG V GVIG+RR +YD+WG V V + ++S GV G+I
Sbjct 683 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKI 726
> mmu:104110 Adcy4, KIAA4004, mKIAA4004; adenylate cyclase 4 (EC:4.6.1.1);
K08044 adenylate cyclase 4 [EC:4.6.1.1]
Length=1077
Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H GS + GVIG ++ +YD+W DV + N +E+ GVPG++
Sbjct 363 INMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 408
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 37/55 (67%), Gaps = 0/55 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQ 59
+R+GL+ G V GVIG+++ +YD+WG V V + +ES GV G+I ++E + Q
Sbjct 985 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQ 1039
> hsa:196883 ADCY4, AC4; adenylate cyclase 4 (EC:4.6.1.1); K08044
adenylate cyclase 4 [EC:4.6.1.1]
Length=1077
Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H GS + GVIG ++ +YD+W DV + N +E+ GVPG++
Sbjct 363 INMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 408
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/55 (41%), Positives = 37/55 (67%), Gaps = 0/55 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQ 59
+R+GL+ G V GVIG+++ +YD+WG V V + +ES GV G+I ++E + Q
Sbjct 983 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQ 1037
> hsa:107 ADCY1, AC1; adenylate cyclase 1 (brain) (EC:4.6.1.1);
K08041 adenylate cyclase 1 [EC:4.6.1.1]
Length=1119
Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats.
Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 0/64 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREE 62
LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ G+PG++ +K +
Sbjct 393 LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDY 452
Query 63 HSEP 66
EP
Sbjct 453 EVEP 456
Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/49 (46%), Positives = 36/49 (73%), Gaps = 0/49 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G++VG V GVIG+RR +YD+WG V V + ++S GV G+I ++E
Sbjct 975 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEE 1023
> mmu:432530 Adcy1, AC1, D11Bwg1392e, I-AC, KIAA4070, brl, mKIAA4070;
adenylate cyclase 1 (EC:4.6.1.1); K08041 adenylate cyclase
1 [EC:4.6.1.1]
Length=1118
Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats.
Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 0/64 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREE 62
LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ G+PG++ +K +
Sbjct 392 LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDY 451
Query 63 HSEP 66
EP
Sbjct 452 EVEP 455
Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/56 (42%), Positives = 38/56 (67%), Gaps = 0/56 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQR 60
+R+G++VG V GVIG+RR +YD+WG V V + ++S GV G+I ++E +R
Sbjct 974 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKR 1029
> dre:569499 adcy1b; adenylate cyclase 1b (EC:4.6.1.1); K08041
adenylate cyclase 1 [EC:4.6.1.1]
Length=1114
Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 34/46 (73%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
LNMR+GLH G + GV+G R+ +YD+W DV + N +E+ G+PG++
Sbjct 371 LNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKV 416
Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats.
Identities = 23/44 (52%), Positives = 34/44 (77%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+R+G++VG V GVIG+RR +YD+WG V V + ++S GVPG+I
Sbjct 955 LRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKI 998
> dre:568726 adcy7, ADCY4a; adenylate cyclase 7 (EC:4.6.1.1);
K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1043
Score = 56.2 bits (134), Expect = 2e-08, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G+ + GVIG R+ ++D+W DV + N +ES G+PG++
Sbjct 371 INMRVGVHSGNVLCGVIGLRKWQFDVWSHDVTLANHMESGGLPGRV 416
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 0/60 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREEHS 64
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E I Q +S
Sbjct 951 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETSIVLQNLGYS 1010
> hsa:113 ADCY7, AC7, FLJ36387, KIAA0037; adenylate cyclase 7
(EC:4.6.1.1); K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1080
Score = 56.2 bits (134), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G+ + GVIG R+ +YD+W DV + N +E+ GVPG++
Sbjct 369 INMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRV 414
Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats.
Identities = 20/49 (40%), Positives = 34/49 (69%), Gaps = 0/49 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E
Sbjct 988 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEE 1036
> dre:557902 adcy2b, si:dkey-266i6.1; adenylate cyclase 2b (brain)
(EC:4.6.1.1); K08042 adenylate cyclase 2 [EC:4.6.1.1]
Length=1139
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ GVPG++
Sbjct 427 INMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 472
Score = 48.9 bits (115), Expect = 4e-06, Method: Composition-based stats.
Identities = 21/49 (42%), Positives = 35/49 (71%), Gaps = 0/49 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
MR+G++ G + GVIG+++ +YD+WG V V + +ES GV G+I ++E
Sbjct 1045 MRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEE 1093
> mmu:210044 Adcy2, MGC47193, mKIAA1060; adenylate cyclase 2 (EC:4.6.1.1);
K08042 adenylate cyclase 2 [EC:4.6.1.1]
Length=1095
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ GVPG++
Sbjct 384 INMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 429
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/57 (33%), Positives = 36/57 (63%), Gaps = 0/57 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQ 59
+R+G++ G + GVIG+++ +YD+WG V V + ++S GV +I ++E + Q
Sbjct 999 FKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQ 1055
> hsa:108 ADCY2, AC2, FLJ16822, FLJ45092, HBAC2, KIAA1060, MGC133314;
adenylate cyclase 2 (brain) (EC:4.6.1.1); K08042 adenylate
cyclase 2 [EC:4.6.1.1]
Length=1091
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G+ + GVIG ++ +YD+W DV + N +E+ GVPG++
Sbjct 380 INMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 425
Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats.
Identities = 19/57 (33%), Positives = 36/57 (63%), Gaps = 0/57 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQ 59
+R+G++ G + GVIG+++ +YD+WG V V + ++S GV +I ++E + Q
Sbjct 995 FKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQ 1051
> dre:560719 si:dkey-206f10.1; K08048 adenylate cyclase 8 [EC:4.6.1.1]
Length=1199
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 25/64 (39%), Positives = 42/64 (65%), Gaps = 4/64 (6%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE----FKISF 58
++MRIG+H GS + GV+G ++ ++D+W DV + N +E+ G+PG+I S+ SF
Sbjct 481 MDMRIGIHTGSVLCGVLGLQKWQFDVWSWDVGIANMLEAGGIPGRIHISRATLDCLDGSF 540
Query 59 QREE 62
Q E+
Sbjct 541 QTED 544
Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+R+G+ G V GVIG+ + +YD+WG+ V + + ++S GV G+I
Sbjct 1053 FQLRVGIAHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGVSGRI 1098
> dre:560410 adenylate cyclase 8-like; K08048 adenylate cyclase
8 [EC:4.6.1.1]
Length=1183
Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats.
Identities = 22/50 (44%), Positives = 37/50 (74%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
++MRIG+H GS + GV+G ++ ++D+W DV V N +E+ G+PG+I S+
Sbjct 476 MDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEAGGIPGRIHISR 525
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 17/44 (38%), Positives = 31/44 (70%), Gaps = 0/44 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+R+G+ G V GVIG+ + +YD+WG+ V + + ++S G+ G+I
Sbjct 1046 LRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSGRI 1089
> dre:563724 adcy2a; adenylate cyclase 2a; K08042 adenylate cyclase
2 [EC:4.6.1.1]
Length=960
Score = 54.7 bits (130), Expect = 7e-08, Method: Composition-based stats.
Identities = 21/51 (41%), Positives = 37/51 (72%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
++MR+G+H G+ + GVIG ++ +YD+W DV + N +E+ GVPG++ + E
Sbjct 244 ISMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITSE 294
Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 34/51 (66%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G++ G GVIG+++ +YD+WG V V + ++S GV G+I ++E
Sbjct 864 FKLRVGINHGPVKAGVIGAQKPQYDIWGNTVNVASRMDSTGVLGKIQVTEE 914
> cel:T01C2.1 acy-4; Adenylyl CYclase family member (acy-4)
Length=1013
Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats.
Identities = 25/53 (47%), Positives = 36/53 (67%), Gaps = 0/53 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFK 55
N+RIG++VG V GVIGS + YD+WG V V + ++S GV G+I ++E K
Sbjct 920 FNLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASRMDSGGVAGRIQVTEEVK 972
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 18/46 (39%), Positives = 32/46 (69%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G GV+G ++ ++D+W DV + N +ES G+ G++
Sbjct 392 VNMRVGIHTGKAHCGVLGLKKWQFDVWSNDVTLANQMESGGLAGRV 437
> mmu:11513 Adcy7, AA407758, MGC141539; adenylate cyclase 7 (EC:4.6.1.1);
K08047 adenylate cyclase 7 [EC:4.6.1.1]
Length=1099
Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats.
Identities = 21/46 (45%), Positives = 35/46 (76%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
++MR+G+H G+ + GVIG R+ +YD+W DV + N +E+ GVPG++
Sbjct 371 ISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRV 416
Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 20/49 (40%), Positives = 34/49 (69%), Gaps = 0/49 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G++ G + GVIG+R+ +YD+WG V V + +ES G G+I ++E
Sbjct 1007 LRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEE 1055
> cel:F17C8.1 acy-1; Adenylyl CYclase family member (acy-1); K08049
adenylate cyclase 9 [EC:4.6.1.1]
Length=1253
Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 19/50 (38%), Positives = 38/50 (76%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G + G++G++R ++D++ DV + N++ES+GV G++ S+
Sbjct 409 VNMRVGIHTGKVMCGMVGTKRFKFDVFSNDVTLANEMESSGVAGRVHVSE 458
Score = 41.2 bits (95), Expect = 9e-04, Method: Composition-based stats.
Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 6/66 (9%)
Query 6 RIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCS---KEF---KISFQ 59
++GL++G GVIG+ +L YD+WG V + + + S GV +I S +E+ + F+
Sbjct 1155 KLGLNIGPVTAGVIGTTKLYYDIWGDTVNIASRMYSTGVLNRIQVSQHTREYLLDRYEFE 1214
Query 60 REEHSE 65
+H E
Sbjct 1215 FRDHIE 1220
> dre:560807 adcy6b, si:ch211-190a18.1; adenylate cyclase 6b;
K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1123
Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1035 FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRI 1080
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 477 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITK 526
> hsa:111 ADCY5, AC5; adenylate cyclase 5 (EC:4.6.1.1); K08045
adenylate cyclase 5 [EC:4.6.1.1]
Length=911
Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 823 FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRI 868
Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 0/66 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREE 62
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K +
Sbjct 209 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDY 268
Query 63 HSEPRC 68
EP C
Sbjct 269 EVEPGC 274
> mmu:224129 Adcy5, AW121902, Ac5; adenylate cyclase 5 (EC:4.6.1.1);
K08045 adenylate cyclase 5 [EC:4.6.1.1]
Length=1262
Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1174 FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRI 1219
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 0/66 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKEFKISFQREE 62
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K +
Sbjct 560 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDY 619
Query 63 HSEPRC 68
EP C
Sbjct 620 EVEPGC 625
> dre:570652 adcy6a, adcy6; adenylate cyclase 6a; K08046 adenylate
cyclase 6 [EC:4.6.1.1]
Length=1174
Score = 52.0 bits (123), Expect = 4e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1086 FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRI 1131
Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 467 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK 516
> mmu:11512 Adcy6, mKIAA0422; adenylate cyclase 6 (EC:4.6.1.1);
K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1168
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1081 FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRI 1126
Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I
Sbjct 469 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRI 514
> hsa:112 ADCY6, AC6, DKFZp779F075, KIAA0422; adenylate cyclase
6 (EC:4.6.1.1); K08046 adenylate cyclase 6 [EC:4.6.1.1]
Length=1168
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1081 FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRI 1126
Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I
Sbjct 469 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRI 514
> mmu:11515 Adcy9, ACtp10, AW125421, D16Wsu65e, mKIAA0520; adenylate
cyclase 9 (EC:4.6.1.1); K08049 adenylate cyclase 9 [EC:4.6.1.1]
Length=1353
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 35/50 (70%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G+ + G++G RR ++D+W DV + N +E GV G++ S+
Sbjct 484 VNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISE 533
Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats.
Identities = 18/51 (35%), Positives = 31/51 (60%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G + G GVIG+ +L YD+WG V + + +++ GV +I S+E
Sbjct 1161 FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEE 1211
> hsa:115 ADCY9, AC9, FLJ12046; adenylate cyclase 9 (EC:4.6.1.1);
K08049 adenylate cyclase 9 [EC:4.6.1.1]
Length=1353
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 35/50 (70%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G+ + G++G RR ++D+W DV + N +E GV G++ S+
Sbjct 484 VNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISE 533
Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats.
Identities = 18/51 (35%), Positives = 31/51 (60%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+R+G + G GVIG+ +L YD+WG V + + +++ GV +I S+E
Sbjct 1161 FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEE 1211
> xla:378610 adcy9, xlAC; adenylate cyclase 9 (EC:4.6.1.1); K08049
adenylate cyclase 9 [EC:4.6.1.1]
Length=1355
Score = 51.2 bits (121), Expect = 7e-07, Method: Composition-based stats.
Identities = 20/51 (39%), Positives = 36/51 (70%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+NMR+G+H G+ + G++G RR ++D+W DV + N +E GV G++ S++
Sbjct 528 VNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEK 578
Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats.
Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+RIG + G GVIG+ +L YD+WG V + + +++ GV +I S+E
Sbjct 1202 FKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQASEE 1252
> dre:562619 adcy5; adenylate cyclase 5 (EC:4.6.1.1); K08045 adenylate
cyclase 5 [EC:4.6.1.1]
Length=1186
Score = 51.2 bits (121), Expect = 8e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1098 FKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERI 1143
Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 489 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK 538
> dre:100332957 adenylate cyclase type 5-like
Length=1397
Score = 50.8 bits (120), Expect = 9e-07, Method: Composition-based stats.
Identities = 22/46 (47%), Positives = 33/46 (71%), Gaps = 0/46 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI 48
M+IGL++G V GVIG+R+ +YD+WG V V + ++S GVP +I
Sbjct 1309 FKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERI 1354
Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 489 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK 538
Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/50 (40%), Positives = 33/50 (66%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G GV+G R+ ++D+W DV + N +E+ G G+I +K
Sbjct 773 VNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITK 822
> cel:T01A4.1 gcy-28; Guanylyl CYclase family member (gcy-28);
K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2]
Length=1276
Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
L +RIG+H GS V GV+GS+ RY L+G V + +ESNG+P +I S++
Sbjct 1178 LKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQ 1228
> dre:100333538 adenylyl cyclase 35C-like
Length=597
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 19/50 (38%), Positives = 35/50 (70%), Gaps = 0/50 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK 52
+NMR+G+H G+ + G++G +R ++D+W DV + N +E GV G++ S+
Sbjct 517 VNMRVGIHTGTVLCGILGMKRFKFDVWSNDVNLANLMEQLGVAGKVHLSE 566
> cel:F23H12.6 gcy-13; Guanylyl CYclase family member (gcy-13);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1035
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSK---EFKISFQ 59
+ +RIG+H GSCV GV+G RY L+G V + +ESNG PG I S + S
Sbjct 944 VQIRIGMHSGSCVAGVVGLTMPRYCLFGDTVNTASRMESNGKPGFIHLSSDCYDLLTSLY 1003
Query 60 REEHSEPR 67
+E ++E R
Sbjct 1004 KEYNTESR 1011
> dre:571825 adcy3l; adenylate cyclase 3-like; K08043 adenylate
cyclase 3 [EC:4.6.1.1]
Length=1071
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 7/63 (11%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQI-------CCSKEFKIS 57
+RIGL+ G+ + GVIG+R+ +D+WG V V + +ES GV G I C K++
Sbjct 967 LRIGLNKGAVLAGVIGARKPHFDIWGNTVNVASRMESTGVMGNIQVVEDCYCILKDYGFR 1026
Query 58 FQR 60
F R
Sbjct 1027 FVR 1029
> cel:M04G12.3 gcy-34; Guanylyl CYclase family member (gcy-34);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=686
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 22/47 (46%), Positives = 33/47 (70%), Gaps = 0/47 (0%)
Query 5 MRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCS 51
+RIGLH G+ + GV+G++ RY L+G V + + +ES GV G+I CS
Sbjct 548 LRIGLHSGTIIAGVVGTKMPRYCLFGETVTLASQMESLGVAGKIQCS 594
> cel:F22E5.3 gcy-21; Guanylyl CYclase family member (gcy-21);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1119
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/49 (44%), Positives = 33/49 (67%), Gaps = 0/49 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCS 51
+ +RIG++ G CV GV+G + RY L+G V + +ESNG+P +I CS
Sbjct 933 VRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGIPLRINCS 981
> cel:T03D8.5 gcy-22; Guanylyl CYclase family member (gcy-22);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1012
Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats.
Identities = 23/51 (45%), Positives = 32/51 (62%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+N+R+GLH G V GV+G RY L+G V + +ESNG PG++ S E
Sbjct 914 INIRVGLHTGPVVTGVVGMTMPRYCLFGDSVNTASRMESNGKPGRVHISTE 964
> cel:F21H7.9 gcy-20; Guanylyl CYclase family member (gcy-20);
K01769 guanylate cyclase, other [EC:4.6.1.2]
Length=1108
Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats.
Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 0/51 (0%)
Query 3 LNMRIGLHVGSCVGGVIGSRRLRYDLWGLDVLVGNDIESNGVPGQICCSKE 53
+N+RIG++ GS V GV+G RY L+G V + +ESNG PGQI + E
Sbjct 969 INLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGQIHVTAE 1019
Lambda K H
0.323 0.145 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2024947620
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40