bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_2109_orf1
Length=149
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_044200 2-oxoglutarate dehydrogenase, putative (EC:1... 190 2e-48
pfa:PF08_0045 2-oxoglutarate dehydrogenase E1 component (EC:1.... 166 2e-41
ath:AT5G65750 2-oxoglutarate dehydrogenase E1 component, putat... 125 6e-29
ath:AT3G55410 2-oxoglutarate dehydrogenase E1 component, putat... 119 3e-27
sce:YIL125W KGD1, OGD1; Component of the mitochondrial alpha-k... 101 8e-22
eco:b0726 sucA, ECK0714, JW0715, lys; 2-oxoglutarate decarboxy... 91.3 1e-18
mmu:18293 Ogdh, 2210403E04Rik, 2210412K19Rik, AA409584, KIAA41... 84.0 2e-16
dre:797715 si:ch211-229p19.3; K00164 2-oxoglutarate dehydrogen... 81.6 8e-16
xla:399021 ogdh, MGC68800, akgdh, e1k, ogdc; oxoglutarate (alp... 81.3 1e-15
xla:444121 MGC80496 protein; K00164 2-oxoglutarate dehydrogena... 80.5 2e-15
dre:564552 ogdh, MGC73296, im:7045267, wu:fa06d01, wu:fb98a04,... 80.1 2e-15
xla:447370 ogdhl, MGC84242; oxoglutarate dehydrogenase-like; K... 80.1 2e-15
mmu:239017 Ogdhl; oxoglutarate dehydrogenase-like (EC:1.2.4.-)... 79.7 3e-15
hsa:55753 OGDHL; oxoglutarate dehydrogenase-like (EC:1.2.4.-);... 79.7 3e-15
dre:559207 hypothetical LOC559207; K00164 2-oxoglutarate dehyd... 79.3 4e-15
cel:T22B11.5 hypothetical protein; K00164 2-oxoglutarate dehyd... 79.3 4e-15
bbo:BBOV_I002070 19.m02351; 2-oxoglutarate dehydrogenase E1 co... 78.6 7e-15
tpv:TP03_0124 2-oxoglutarate dehydrogenase e1 component (EC:1.... 77.8 1e-14
mmu:209692 Dhtkd1, C330018I04Rik; dehydrogenase E1 and transke... 72.4 5e-13
dre:100334699 probable 2-oxoglutarate dehydrogenase E1 compone... 70.9 1e-12
dre:494076 dhtkd1, zgc:101818; dehydrogenase E1 and transketol... 70.9 1e-12
xla:403360 dhtkd1, MGC68840; dehydrogenase E1 and transketolas... 70.1 2e-12
hsa:55526 DHTKD1, DKFZp762M115, KIAA1630, MGC3090; dehydrogena... 67.0 2e-11
cel:ZK836.2 hypothetical protein 63.5 2e-10
dre:100331749 oxoglutarate (alpha-ketoglutarate) dehydrogenase... 55.5 7e-08
xla:446562 dapk1, MGC81366; death-associated protein kinase 1 ... 35.4 0.070
cel:F22B8.6 hypothetical protein; K01758 cystathionine gamma-l... 31.6 1.0
hsa:57038 RARS2, ArgRS, DALRD2, MGC14993, MGC23778, PCH6, PRO1... 30.4 2.4
cel:K01A11.4 spe-41; defective SPErmatogenesis family member (... 30.0 2.7
ath:AT5G05450 DEAD/DEAH box helicase, putative (RH18); K14809 ... 29.3 4.6
> tgo:TGME49_044200 2-oxoglutarate dehydrogenase, putative (EC:1.2.4.2);
K00164 2-oxoglutarate dehydrogenase E1 component
[EC:1.2.4.2]
Length=1116
Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 87/149 (58%), Positives = 108/149 (72%), Gaps = 0/149 (0%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALREL 60
D+ ++K +I FYN EYE + F+P+ Q +Y+PQWKHLV PD P+ P++TGV L LREL
Sbjct 626 DLQQLKQNILAFYNAEYEKCRDFLPSQQYEYSPQWKHLVRPDVPAAPQLTGVPLDRLREL 685
Query 61 GRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLA 120
G +IFT+P F H T+ KI K+RL A + E +DFG AENL YATLLSDGFH+R+A
Sbjct 686 GTKIFTLPPDFNVHPTVGKIYKERLNAIQAAPDENLIDFGTAENLCYATLLSDGFHVRIA 745
Query 121 GQDAQRGTFSHRHAVLHDQAVEAQHCIFD 149
GQD QRGTFSHRHAVLHDQ + IFD
Sbjct 746 GQDVQRGTFSHRHAVLHDQTTFEPYSIFD 774
> pfa:PF08_0045 2-oxoglutarate dehydrogenase E1 component (EC:1.2.4.2);
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=1038
Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats.
Identities = 79/144 (54%), Positives = 99/144 (68%), Gaps = 3/144 (2%)
Query 6 KSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRRIF 65
K++I+ FY + YE SK+FVP + +Y PQW+H+VTP SP R TGV L LG++IF
Sbjct 562 KTEIFNFYEQVYEKSKSFVPTPKEKYLPQWEHMVTPQKFSPSRKTGVEKDVLINLGKKIF 621
Query 66 TIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQDAQ 125
T+ E F H I K+ K R+ + E + +DFG AE LAYATLLSDGFH RL+GQD+Q
Sbjct 622 TLRENFTAHPIITKLFKSRI---DSLETGKNIDFGTAELLAYATLLSDGFHARLSGQDSQ 678
Query 126 RGTFSHRHAVLHDQAVEAQHCIFD 149
RGTFSHRHAVLHDQ + IFD
Sbjct 679 RGTFSHRHAVLHDQITYESYNIFD 702
> ath:AT5G65750 2-oxoglutarate dehydrogenase E1 component, putative
/ oxoglutarate decarboxylase, putative / alpha-ketoglutaric
dehydrogenase, putative; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1025
Score = 125 bits (313), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 59/149 (39%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALREL 60
D+ +++ + N+EYE+SK ++P + A W +P+ S R TGV+ L+ +
Sbjct 546 DIDKIQKKVSSILNEEYEASKDYIPQKRDWLASHWTGFKSPEQISRIRNTGVKPEILKNV 605
Query 61 GRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLA 120
G+ I T PE F PH + ++ +QR A+ E + +D+G E LA+ATL+ +G H+RL+
Sbjct 606 GKAISTFPENFKPHRGVKRVYEQR---AQMIESGEGIDWGLGEALAFATLVVEGNHVRLS 662
Query 121 GQDAQRGTFSHRHAVLHDQAVEAQHCIFD 149
GQD +RGTFSHRH+VLHDQ ++C D
Sbjct 663 GQDVERGTFSHRHSVLHDQETGEEYCPLD 691
> ath:AT3G55410 2-oxoglutarate dehydrogenase E1 component, putative
/ oxoglutarate decarboxylase, putative / alpha-ketoglutaric
dehydrogenase, putative; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1017
Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 57/149 (38%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALREL 60
D+ R++ + N+E+ +SK ++P + + W +P+ S R TGV+ L+ +
Sbjct 542 DIDRIQEKVNTILNEEFVASKDYLPKKRDWLSTNWAGFKSPEQISRVRNTGVKPEILKTV 601
Query 61 GRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLA 120
G+ I ++PE F PH + K+ +QR A+ E + +D+ AE LA+ATL+ +G H+RL+
Sbjct 602 GKAISSLPENFKPHRAVKKVYEQR---AQMIESGEGVDWALAEALAFATLVVEGNHVRLS 658
Query 121 GQDAQRGTFSHRHAVLHDQAVEAQHCIFD 149
GQD +RGTFSHRH+VLHDQ ++C D
Sbjct 659 GQDVERGTFSHRHSVLHDQETGEEYCPLD 687
> sce:YIL125W KGD1, OGD1; Component of the mitochondrial alpha-ketoglutarate
dehydrogenase complex, which catalyzes a key
step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation
of alpha-ketoglutarate to form succinyl-CoA (EC:1.2.4.2);
K00164 2-oxoglutarate dehydrogenase E1 component
[EC:1.2.4.2]
Length=1014
Score = 101 bits (252), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 53/147 (36%), Positives = 82/147 (55%), Gaps = 7/147 (4%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPS----PPRVTGVRLSA 56
D+ K +W + +E +K +VP+ + W+ +P + P T V S
Sbjct 549 DIDEHKKWVWNLFEDAFEKAKDYVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPEST 608
Query 57 LRELGRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFH 116
L+ELG+ + + PEGF H + +I+K R + E E +D+ E LA+ TL+ DG +
Sbjct 609 LKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGE---GIDWATGEALAFGTLVLDGQN 665
Query 117 IRLAGQDAQRGTFSHRHAVLHDQAVEA 143
+R++G+D +RGTFS RHAVLHDQ EA
Sbjct 666 VRVSGEDVERGTFSQRHAVLHDQQSEA 692
> eco:b0726 sucA, ECK0714, JW0715, lys; 2-oxoglutarate decarboxylase,
thiamin-requiring (EC:1.2.4.2); K00164 2-oxoglutarate
dehydrogenase E1 component [EC:1.2.4.2]
Length=933
Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 48/114 (42%), Positives = 70/114 (61%), Gaps = 8/114 (7%)
Query 27 HQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRRIFTIPEGFVPHATIAKIMKQRLA 86
H ++P H ++P+ V + L+EL +RI T+PE + +AKI R A
Sbjct 529 HSFTWSPYLNHEWDEEYPNK-----VEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQA 583
Query 87 AAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQA 140
A G E+ D+G AENLAYATL+ +G +RL+G+D+ RGTF HRHAV+H+Q+
Sbjct 584 MAAG---EKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQS 634
> mmu:18293 Ogdh, 2210403E04Rik, 2210412K19Rik, AA409584, KIAA4192,
d1401, mKIAA4192; oxoglutarate dehydrogenase (lipoamide)
(EC:1.2.4.2); K00164 2-oxoglutarate dehydrogenase E1 component
[EC:1.2.4.2]
Length=1023
Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 41/99 (41%), Positives = 62/99 (62%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G+ ++P E F H +++I+K R +T+D+ AE +A+
Sbjct 607 TGLEEDVLFHIGKVASSVPVENFTIHGGLSRILKTRRELVTN----RTVDWALAEYMAFG 662
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ + CI
Sbjct 663 SLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCI 701
> dre:797715 si:ch211-229p19.3; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1023
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 39/99 (39%), Positives = 62/99 (62%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G+ ++P E F H +++I+K R + +++D+ E +A+
Sbjct 608 TGLSEETLAHIGQTASSVPVEDFTIHGGLSRILKSRSLMVQN----RSVDWALGEYMAFG 663
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ + CI
Sbjct 664 SLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCI 702
> xla:399021 ogdh, MGC68800, akgdh, e1k, ogdc; oxoglutarate (alpha-ketoglutarate)
dehydrogenase (lipoamide) (EC:1.2.4.2);
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=1021
Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 42/99 (42%), Positives = 62/99 (62%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G ++P E F+ H +++I+K R + +T+D+ AE +A
Sbjct 606 TGLTEEDLTHIGNVASSVPVEDFMIHGGLSRILKGRGEMVKN----RTVDWALAEYMALG 661
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G HIRL+GQD +RGTFSHRH VLHDQ V+ + CI
Sbjct 662 SLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCI 700
> xla:444121 MGC80496 protein; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1018
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 41/99 (41%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G ++P E F H +++I+K R + +T+D+ AE ++
Sbjct 603 TGLSEEELTHIGNVASSVPVEDFTIHGGLSRILKGRGEMVKN----RTVDWALAEYMSLG 658
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G HIRL+GQD +RGTFSHRH VLHDQ V+ + CI
Sbjct 659 SLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCI 697
> dre:564552 ogdh, MGC73296, im:7045267, wu:fa06d01, wu:fb98a04,
zgc:73296; oxoglutarate (alpha-ketoglutarate) dehydrogenase
(lipoamide) (EC:1.2.4.2); K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1022
Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 40/99 (40%), Positives = 63/99 (63%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L ++G+ ++P E F H +++I+K R + +T+D+ E +A+
Sbjct 607 TGLPEEELAQIGQVASSVPVEDFTIHGGLSRILKGRGDMIKN----RTVDWALGEYMAFG 662
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ + CI
Sbjct 663 SLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICI 701
> xla:447370 ogdhl, MGC84242; oxoglutarate dehydrogenase-like;
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=1018
Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 41/103 (39%), Positives = 63/103 (61%), Gaps = 7/103 (6%)
Query 46 PPRVTGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAEN 104
PP TG+ L +G ++P + F H +++I+K RL + +T+D+ AE
Sbjct 600 PP--TGIPEDMLSHIGAIASSVPLKDFKIHGGLSRILKSRLEMT----NSRTVDWALAEY 653
Query 105 LAYATLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+ + +LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ C+
Sbjct 654 MTFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRWTCV 696
> mmu:239017 Ogdhl; oxoglutarate dehydrogenase-like (EC:1.2.4.-);
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=1029
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 39/99 (39%), Positives = 63/99 (63%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G ++P E F H +++I++ R + ++T+D+ AE +A+
Sbjct 613 TGIPEEMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTK----KRTVDWALAEYMAFG 668
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ + C+
Sbjct 669 SLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCV 707
> hsa:55753 OGDHL; oxoglutarate dehydrogenase-like (EC:1.2.4.-);
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=953
Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 39/99 (39%), Positives = 62/99 (62%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L +G ++P E F H +++I++ R + +T+D+ AE +A+
Sbjct 537 TGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKN----RTVDWALAEYMAFG 592
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL +G H+RL+GQD +RGTFSHRH VLHDQ V+ + C+
Sbjct 593 SLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCV 631
> dre:559207 hypothetical LOC559207; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1008
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 38/99 (38%), Positives = 62/99 (62%), Gaps = 5/99 (5%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L+ +G ++P + F H+ +++I++ R ++ D+ AE +A+
Sbjct 593 TGLSEEVLKHIGEVASSVPLKDFAIHSGLSRILRGRADMIT----KRMADWALAEYMAFG 648
Query 109 TLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCI 147
+LL DG H+RL+GQD +RGTFSHRH VLHDQ V+ + C+
Sbjct 649 SLLKDGIHVRLSGQDVERGTFSHRHHVLHDQEVDKRFCV 687
> cel:T22B11.5 hypothetical protein; K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=1029
Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 4/108 (3%)
Query 35 WKHLVTPDHPSPPRVTGVRLSALRELGRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHE 94
W P TG+ + ++ + PEGF H + + +K R + +
Sbjct 593 WDDFFKKRDPLKLPSTGIEQENIEQIIGKFSQYPEGFNLHRGLERTLKGRQQMLK----D 648
Query 95 QTLDFGAAENLAYATLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVE 142
+LD+ E LA+ +LL +G H+RL+GQD QRGTFSHRH VLHDQ V+
Sbjct 649 NSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVD 696
> bbo:BBOV_I002070 19.m02351; 2-oxoglutarate dehydrogenase E1
component (EC:1.2.4.2); K00164 2-oxoglutarate dehydrogenase
E1 component [EC:1.2.4.2]
Length=891
Score = 78.6 bits (192), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 51/145 (35%), Positives = 75/145 (51%), Gaps = 8/145 (5%)
Query 5 MKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRRI 64
++S+I + + SK V ++ WK P P VTGV L ELG+ +
Sbjct 445 IESEIQDVFEAALKKSKDIVDIPLPPHSLNWK---IP--PLSSTVTGVEPHRLVELGKAL 499
Query 65 FTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQDA 124
+P+ + H I +I +R A E + +D G AE LAYA+L DG+ +RL GQD+
Sbjct 500 NGVPQDYQLHPAIRRIYNERSKAIEAGNN---IDTGLAEALAYASLAEDGYRVRLVGQDS 556
Query 125 QRGTFSHRHAVLHDQAVEAQHCIFD 149
+RGTFSHRH+ + Q IF+
Sbjct 557 KRGTFSHRHSSVQCQKTFRFFNIFE 581
> tpv:TP03_0124 2-oxoglutarate dehydrogenase e1 component (EC:1.2.4.2);
K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Length=1030
Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats.
Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 3/107 (2%)
Query 42 DHPSPPRVTGVRLSALRELGRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGA 101
D PP TG+ + L ELG + T+P H ++ KI RL + D
Sbjct 591 DKLDPPVETGLDKNLLLELGTKCVTVPSDIKMHNSVKKIFDARLQCLSTGSN---FDTAM 647
Query 102 AENLAYATLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQHCIF 148
+E LA+++L ++GFH+RL+GQ+++RGTFSHRH+ + Q H IF
Sbjct 648 SEILAFSSLANEGFHVRLSGQESKRGTFSHRHSHVQCQTTFKYHNIF 694
> mmu:209692 Dhtkd1, C330018I04Rik; dehydrogenase E1 and transketolase
domain containing 1 (EC:1.2.4.2)
Length=921
Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 46/136 (33%), Positives = 72/136 (52%), Gaps = 3/136 (2%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALREL 60
+VS +K+ + N + + P A +W+ LV P+ TGV L LR +
Sbjct 477 EVSDIKTSYYTKLNDHLANVAHYSPPATNLQA-RWQGLVQPEACVTTWDTGVPLELLRFI 535
Query 61 GRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLA 120
G + +PE H+ + K+ Q + E ++ LD+ AE LA +LL+ GF++RL+
Sbjct 536 GVKSVEVPEELQVHSHLLKMYVQ--SRMEKVKNGSGLDWATAETLALGSLLAQGFNVRLS 593
Query 121 GQDAQRGTFSHRHAVL 136
GQD RGTFS RHA++
Sbjct 594 GQDVGRGTFSQRHAMV 609
> dre:100334699 probable 2-oxoglutarate dehydrogenase E1 component
DHKTD1, mitochondrial-like
Length=657
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Query 3 SRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGR 62
S++K+ + N + + + P +W LV P + TGV L+ +G
Sbjct 484 SQIKTSYYATLNNQLTNMTLYSPP-PTNLQGRWGDLVEPQNRVSCWDTGVAQPLLQFVGA 542
Query 63 RIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQ 122
+ IPE + H+ + K Q A + E LD+ AE LA+ TLL GF+IR++GQ
Sbjct 543 KSVDIPEEIILHSHLRKTHVQ--ARLQKLEEGTKLDWSTAEALAFGTLLCQGFNIRISGQ 600
Query 123 DAQRGTFSHRHAVL 136
D RGTFS RHA++
Sbjct 601 DVGRGTFSQRHAMV 614
> dre:494076 dhtkd1, zgc:101818; dehydrogenase E1 and transketolase
domain containing 1 (EC:1.2.4.2)
Length=925
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Query 3 SRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGR 62
S++K+ + N + + + P +W LV P + TGV L+ +G
Sbjct 484 SQIKTSYYATLNNQLTNMTLYSPP-PTNLQGRWGDLVEPQNRVSCWDTGVAQPLLQFVGA 542
Query 63 RIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQ 122
+ IPE + H+ + K Q A + E LD+ AE LA+ TLL GF+IR++GQ
Sbjct 543 KSVDIPEEIILHSHLRKTHVQ--ARLQKLEEGTKLDWSTAEALAFGTLLCQGFNIRISGQ 600
Query 123 DAQRGTFSHRHAVL 136
D RGTFS RHA++
Sbjct 601 DVGRGTFSQRHAMV 614
> xla:403360 dhtkd1, MGC68840; dehydrogenase E1 and transketolase
domain containing 1 (EC:1.2.4.2)
Length=927
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query 12 FYNK--EYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRRIFTIPE 69
+Y+K ++ S+ T W+ ++ P + TG+ L+ +G + +PE
Sbjct 492 YYSKFNDHLSNMTLYSPPSTNLQAHWREMIEPSARTTTWDTGLPADLLKFIGAKSVEVPE 551
Query 70 GFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQDAQRGTF 129
F H+ + K+ Q + + + LD+ AE LA+ +LL GF+IR++GQD RGTF
Sbjct 552 EFKMHSHLLKMHAQ--SRVQKLQEATKLDWATAEALAFGSLLCQGFNIRISGQDVGRGTF 609
Query 130 SHRHAVL 136
S RHA+L
Sbjct 610 SQRHAML 616
> hsa:55526 DHTKD1, DKFZp762M115, KIAA1630, MGC3090; dehydrogenase
E1 and transketolase domain containing 1 (EC:1.2.4.2)
Length=919
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 44/136 (32%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query 1 DVSRMKSDIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALREL 60
+VS +KS + N + + P W+ L P+ TGV L LR +
Sbjct 476 EVSEIKSSYYAKLNDHLNNMAHYRPP-ALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFV 534
Query 61 GRRIFTIPEGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLA 120
G + +P H+ + K Q + E LD+ AE LA +LL+ GF++RL+
Sbjct 535 GMKSVEVPRELQMHSHLLKTHVQ--SRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLS 592
Query 121 GQDAQRGTFSHRHAVL 136
GQD RGTFS RHA++
Sbjct 593 GQDVGRGTFSQRHAIV 608
> cel:ZK836.2 hypothetical protein
Length=911
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 10/100 (10%)
Query 50 TGVRLSALRELGRRIFTIPEGFVPHATIAKI----MKQRLAAAEGPEHEQTLDFGAAENL 105
TGV LR +G +PE F H + K+ Q++ EG +D+ AE +
Sbjct 514 TGVATDLLRFIGAGSVKVPEDFDTHKHLYKMHIDSRMQKMQTGEG------IDWATAEAM 567
Query 106 AYATLLSDGFHIRLAGQDAQRGTFSHRHAVLHDQAVEAQH 145
A+ ++L +G +R++GQD RGTF HRHA++ DQ+ + H
Sbjct 568 AFGSILLEGNDVRISGQDVGRGTFCHRHAMMVDQSTDHIH 607
> dre:100331749 oxoglutarate (alpha-ketoglutarate) dehydrogenase
(lipoamide)-like
Length=687
Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 28/81 (34%), Positives = 49/81 (60%), Gaps = 5/81 (6%)
Query 50 TGVRLSALRELGRRIFTIP-EGFVPHATIAKIMKQRLAAAEGPEHEQTLDFGAAENLAYA 108
TG+ L ++G+ ++P E F H +++I+K R + +T+D+ E +A+
Sbjct 607 TGLPEEELAQIGQVASSVPVEDFTIHGGLSRILKGRGDMIKN----RTVDWALGEYMAFG 662
Query 109 TLLSDGFHIRLAGQDAQRGTF 129
+LL +G H+RL+GQD +RGTF
Sbjct 663 SLLKEGIHVRLSGQDVERGTF 683
> xla:446562 dapk1, MGC81366; death-associated protein kinase
1 (EC:2.7.1.-); K08803 death-associated protein kinase [EC:2.7.11.1]
Length=1427
Score = 35.4 bits (80), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Query 8 DIWGFYNKEYESSKTFVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRR 63
D+ YN K F+P+ C +W + SP + +S LRELGRR
Sbjct 1335 DLVAKYNANNSVQKDFLPSPICALLQEWSN-------SPESTVSLLMSKLRELGRR 1383
> cel:F22B8.6 hypothetical protein; K01758 cystathionine gamma-lyase
[EC:4.4.1.1]
Length=392
Score = 31.6 bits (70), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query 80 IMKQRLAAAEGPEHEQTLDFGAAENLAYATLLSDGFHIRLAGQDAQRGTFSH 131
++++ LAA EG +H Q G A + A LL+ G HI + D GT +
Sbjct 59 VLQKNLAALEGAKHCQAFSSGLAASSAVINLLNHGDHI-VCSDDVYGGTIRY 109
> hsa:57038 RARS2, ArgRS, DALRD2, MGC14993, MGC23778, PCH6, PRO1992,
RARSL, dJ382I10.6; arginyl-tRNA synthetase 2, mitochondrial
(EC:6.1.1.19); K01887 arginyl-tRNA synthetase [EC:6.1.1.19]
Length=578
Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 6/44 (13%)
Query 17 YESSKTFVPAHQCQYAPQWKHLVTPDHP------SPPRVTGVRL 54
Y+SS+ F P H Y HL H SPP V G RL
Sbjct 510 YKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAGARL 553
> cel:K01A11.4 spe-41; defective SPErmatogenesis family member
(spe-41); K05328 transient receptor potential cation channel
subfamily C, invertebrate
Length=854
Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 10/77 (12%)
Query 23 FVPAHQCQYAPQWKHLVTPDHPSPPRVTGVRLSALRELGRRIFTIPEGFVPHATIAKIMK 82
FV + +C+Y W+ + PPRVT + A L F EGF K+
Sbjct 720 FVASKECKYKSIWRSEFHREEKQPPRVTFLTTGAHSFLMDNTF---EGF-------KMRS 769
Query 83 QRLAAAEGPEHEQTLDF 99
R AEG + T+ +
Sbjct 770 SRTMEAEGYKEYTTVQY 786
> ath:AT5G05450 DEAD/DEAH box helicase, putative (RH18); K14809
ATP-dependent RNA helicase DDX55/SPB4 [EC:3.6.4.13]
Length=593
Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats.
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query 44 PSPPRVTGVRLSALRELGRRIFTIPEGFVPHATIAKI 80
P P +V GV +S REL +I+ + + FV +T+A +
Sbjct 86 PKPHQVMGVIISPTRELSTQIYNVAQPFV--STLANV 120
Lambda K H
0.321 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 3068761412
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40