bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
164,496 sequences; 82,071,388 total letters
Query= Eace_3330_orf1
Length=86
Score E
Sequences producing significant alignments: (Bits) Value
dre:559023 serine/threonine protein kinase MST4-like 73.9 1e-13
dre:100151762 zgc:175288 73.9 1e-13
hsa:51765 MST4, MASK; serine/threonine protein kinase MST4 (EC... 70.9 1e-12
xla:444523 mst4, MGC82018; serine/threonine protein kinase MST... 70.5 1e-12
mmu:70415 2610018G03Rik, Mst4; RIKEN cDNA 2610018G03 gene (EC:... 70.1 1e-12
tgo:TGME49_025960 serine/threonine-protein kinase, putative (E... 69.7 2e-12
dre:406786 stk24b, stk24, wu:fi29b08, zgc:66137; serine/threon... 69.3 3e-12
ath:AT3G15220 protein kinase, putative 69.3 3e-12
dre:406600 stk25b, stk25, zgc:56022, zgc:77029; serine/threoni... 69.3 3e-12
xla:432004 stk25, MGC80023, sok-1, sok1, ysk1; serine/threonin... 68.9 3e-12
dre:555297 stk24a, zgc:163071; serine/threonine kinase 24a (ST... 68.9 4e-12
ath:AT1G53165 ATMAP4K ALPHA1; ATP binding / kinase/ protein ki... 68.9 4e-12
dre:449653 stk25a, zgc:92836; serine/threonine kinase 25a 68.9 4e-12
hsa:10494 STK25, DKFZp686J1430, SOK1, YSK1; serine/threonine k... 68.6 5e-12
mmu:59041 Stk25, 1500019J11Rik, AU018434, C86992, Ste20-like, ... 68.6 5e-12
xla:444155 stk24, MGC80614; serine/threonine kinase 24 (EC:2.7... 68.2 6e-12
mmu:223255 Stk24, 1810013H02Rik, C76483, MGC6330, Mst3; serine... 68.2 7e-12
hsa:8428 STK24, MST3, MST3B, STE20, STK3; serine/threonine kin... 68.2 7e-12
ath:AT1G70430 protein kinase family protein 67.8 8e-12
dre:100005183 map4k3; mitogen-activated protein kinase kinase ... 67.8 8e-12
xla:447339 map4k5, MGC83247; mitogen-activated protein kinase ... 67.0 1e-11
mmu:225028 Map4k3, 4833416M01Rik, 4833416M07Rik, 9530052P13Rik... 66.6 2e-11
hsa:8491 MAP4K3, GLK, MAPKKKK3, MEKKK_3, RAB8IPL1; mitogen-act... 66.6 2e-11
dre:558281 mitogen-activated protein kinase kinase kinase kina... 66.6 2e-11
dre:561669 mitogen-activated protein kinase kinase kinase kina... 66.6 2e-11
hsa:50488 MINK1, B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK... 66.6 2e-11
mmu:50932 Mink1, B55, MINK, Map4k6, RP23-122P1.6, Ysk2; missha... 66.6 2e-11
cel:ZC404.9 gck-2; Germinal Center Kinase family member (gck-2... 66.6 2e-11
ath:AT5G14720 protein kinase family protein 66.2 2e-11
xla:414526 MGC81311, taok1-a; serine/threonine-protein kinase ... 66.2 2e-11
dre:100333250 misshapen-like kinase 1-like; K04413 misshapen/N... 65.9 3e-11
mmu:216965 Taok1, 2810468K05Rik, AU020252, D130018F14Rik, MGC2... 65.9 3e-11
hsa:57551 TAOK1, FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO... 65.9 3e-11
dre:100004576 TAO kinase 1-like; K04429 thousand and one amino... 65.9 3e-11
xla:446555 mink1, MGC81192, mink; misshapen-like kinase 1 (EC:... 65.9 3e-11
dre:334565 map4k5, MGC55719, fl74c10, wu:fl74c10, zgc:55719, z... 65.5 4e-11
mmu:53416 Stk39, AW227544, AW556857, DCHT, RF005, Rnl5, SPAK; ... 65.5 4e-11
cel:ZC504.4 mig-15; abnormal cell MIGration family member (mig... 65.5 4e-11
dre:554108 zgc:112307 65.5 4e-11
dre:100334915 serine/threonine-protein kinase TAO1-like 65.5 4e-11
hsa:27347 STK39, DCHT, DKFZp686K05124, PASK, SPAK; serine thre... 65.5 4e-11
dre:394150 oxsr1b, MGC55494, zgc:55494, zgc:77321; oxidative-s... 65.1 5e-11
mmu:665113 Tnik, 1500031A17Rik, 4831440I19Rik, AI451411, C5300... 65.1 5e-11
hsa:23043 TNIK; TRAF2 and NCK interacting kinase (EC:2.7.11.1)... 65.1 5e-11
hsa:11183 MAP4K5, GCKR, KHS, KHS1, MAPKKKK5; mitogen-activated... 65.1 5e-11
cel:C09B8.7 pak-1; P21-Activated Kinase family member (pak-1);... 65.1 6e-11
mmu:399510 Map4k5, 4432415E19Rik, GCKR, KHS, MAPKKKK5; mitogen... 64.7 6e-11
xla:446778 taok3, MGC80412; TAO kinase 3 (EC:2.7.11.1); K04429... 64.7 6e-11
xla:379165 taok1, MGC52943, taok1-b; TAO kinase 1 (EC:2.7.11.1... 64.7 6e-11
hsa:51347 TAOK3, DKFZp666H245, DPK, FLJ31808, JIK, MAP3K18; TA... 64.7 6e-11
> dre:559023 serine/threonine protein kinase MST4-like
Length=412
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 43/81 (53%), Positives = 51/81 (62%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +LK++L L YLH E IHRD+KAAN+LLSESG KL DFG++ L
Sbjct 121 IATMLKEILKGLDYLHS-----------EKKIHRDIKAANVLLSESGEVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K E F GTP WMAPEV
Sbjct 170 TDTQIKRETFVGTPFWMAPEV 190
> dre:100151762 zgc:175288
Length=412
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 43/81 (53%), Positives = 51/81 (62%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +LK++L L YLH E IHRD+KAAN+LLSESG KL DFG++ L
Sbjct 121 IATMLKEILKGLDYLHS-----------EKKIHRDIKAANVLLSESGEVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K E F GTP WMAPEV
Sbjct 170 TDTQIKRETFVGTPFWMAPEV 190
> hsa:51765 MST4, MASK; serine/threonine protein kinase MST4 (EC:2.7.11.1);
K08282 non-specific serine/threonine protein kinase
[EC:2.7.11.1]
Length=354
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 41/81 (50%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +LK++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATMLKEILKGLDYLHS-----------EKKIHRDIKAANVLLSEQGDVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> xla:444523 mst4, MGC82018; serine/threonine protein kinase MST4
(EC:2.7.11.1)
Length=413
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 41/81 (50%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +LK++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATMLKEILKGLDYLHS-----------ENKIHRDIKAANVLLSEQGDVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> mmu:70415 2610018G03Rik, Mst4; RIKEN cDNA 2610018G03 gene (EC:2.7.11.1)
Length=416
Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 41/81 (50%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +LK++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATMLKEILKGLDYLHS-----------EKKIHRDIKAANVLLSEQGDVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> tgo:TGME49_025960 serine/threonine-protein kinase, putative
(EC:2.7.11.1 3.1.3.48)
Length=3956
Score = 69.7 bits (169), Expect = 2e-12, Method: Composition-based stats.
Identities = 48/114 (42%), Positives = 58/114 (50%), Gaps = 35/114 (30%)
Query 1 IIAHLLKDVLSALVYLH------------------GREVG--PEGK-------------I 27
+IA LL+DVL AL YLH EVG PE +
Sbjct 1725 LIAALLQDVLKALKYLHNGGEAEAAGARNEGKHKNAEEVGARPEAEETGDGPSAEAARAA 1784
Query 28 KKEVCIHRDLKAANILLSESGTAKLIDFGI--SVLSDKDEEFAGTPQWMAPEVA 79
K+ +HRDLKA+NIL+S G AKLIDFG+ + EF GTPQWMAPE+A
Sbjct 1785 KQPRRMHRDLKASNILISAEGRAKLIDFGVCADITDSLCTEFVGTPQWMAPELA 1838
> dre:406786 stk24b, stk24, wu:fi29b08, zgc:66137; serine/threonine
kinase 24b (STE20 homolog, yeast) (EC:2.7.11.1); K08838
serine/threonine kinase 24 [EC:2.7.11.1]
Length=420
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 109 IATILREILKGLEYLHS-----------EKKIHRDIKAANVLLSEQGEVKLADFGVAGQL 157
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 158 TDTQIKRNTFVGTPFWMAPEV 178
> ath:AT3G15220 protein kinase, putative
Length=690
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 50/81 (61%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISV-- 59
IA + +D+L A+ YLH EGKI HRD+KAANILLSE+G K+ DFG+S
Sbjct 113 IACITRDLLHAVEYLHN-----EGKI------HRDIKAANILLSENGDVKVADFGVSAQL 161
Query 60 --LSDKDEEFAGTPQWMAPEV 78
+ + F GTP WMAPEV
Sbjct 162 TRTISRRKTFVGTPFWMAPEV 182
> dre:406600 stk25b, stk25, zgc:56022, zgc:77029; serine/threonine
kinase 25b (EC:2.7.11.1); K08839 serine/threonine kinase
25 [EC:2.7.11.22]
Length=424
Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 117 IATILREILKGLEYLHS-----------ERKIHRDIKAANVLLSEQGDVKLADFGVAGQL 165
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 166 TDTQIKRNTFVGTPFWMAPEV 186
> xla:432004 stk25, MGC80023, sok-1, sok1, ysk1; serine/threonine
kinase 25; K08839 serine/threonine kinase 25 [EC:2.7.11.22]
Length=400
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 104 IATILREILKGLDYLHS-----------ERKIHRDIKAANVLLSEQGDVKLADFGVAGQL 152
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 153 TDTQIKRNTFVGTPFWMAPEV 173
> dre:555297 stk24a, zgc:163071; serine/threonine kinase 24a (STE20
homolog, yeast)
Length=415
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 114 IATILREILKGLDYLHS-----------EKKIHRDIKAANVLLSEQGDVKLADFGVAGQL 162
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 163 TDTQIKRNTFVGTPFWMAPEV 183
> ath:AT1G53165 ATMAP4K ALPHA1; ATP binding / kinase/ protein
kinase/ protein serine/threonine kinase/ protein tyrosine kinase
Length=680
Score = 68.9 bits (167), Expect = 4e-12, Method: Composition-based stats.
Identities = 40/81 (49%), Positives = 50/81 (61%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISV-- 59
IA + +D+L A+ YLH EGKI HRD+KAANILLSE+G K+ DFG+S
Sbjct 113 IACITRDLLHAVEYLHA-----EGKI------HRDIKAANILLSENGDVKVADFGVSAQL 161
Query 60 --LSDKDEEFAGTPQWMAPEV 78
+ + F GTP WMAPEV
Sbjct 162 TRTISRRKTFVGTPFWMAPEV 182
> dre:449653 stk25a, zgc:92836; serine/threonine kinase 25a
Length=297
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 117 IATILREILKGLDYLHS-----------ERKIHRDIKAANVLLSEHGEVKLADFGVAGQL 165
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 166 TDTQIKRNTFVGTPFWMAPEV 186
> hsa:10494 STK25, DKFZp686J1430, SOK1, YSK1; serine/threonine
kinase 25 (EC:2.7.11.1); K08839 serine/threonine kinase 25
[EC:2.7.11.22]
Length=426
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 117 IATILREILKGLDYLHS-----------ERKIHRDIKAANVLLSEQGDVKLADFGVAGQL 165
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 166 TDTQIKRNTFVGTPFWMAPEV 186
> mmu:59041 Stk25, 1500019J11Rik, AU018434, C86992, Ste20-like,
Ysk1; serine/threonine kinase 25 (yeast) (EC:2.7.11.1); K08839
serine/threonine kinase 25 [EC:2.7.11.22]
Length=426
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 117 IATILREILKGLDYLHS-----------ERKIHRDIKAANVLLSEQGDVKLADFGVAGQL 165
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 166 TDTQIKRNTFVGTPFWMAPEV 186
> xla:444155 stk24, MGC80614; serine/threonine kinase 24 (EC:2.7.11.1);
K08838 serine/threonine kinase 24 [EC:2.7.11.1]
Length=424
Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATILREILKGLDYLHS-----------EKKIHRDIKAANVLLSEHGEVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> mmu:223255 Stk24, 1810013H02Rik, C76483, MGC6330, Mst3; serine/threonine
kinase 24 (STE20 homolog, yeast) (EC:2.7.11.1);
K08838 serine/threonine kinase 24 [EC:2.7.11.1]
Length=431
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATILREILKGLDYLHS-----------EKKIHRDIKAANVLLSEHGEVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> hsa:8428 STK24, MST3, MST3B, STE20, STK3; serine/threonine kinase
24 (EC:2.7.11.1); K08838 serine/threonine kinase 24 [EC:2.7.11.1]
Length=431
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-VL 60
IA +L+++L L YLH E IHRD+KAAN+LLSE G KL DFG++ L
Sbjct 121 IATILREILKGLDYLHS-----------EKKIHRDIKAANVLLSEHGEVKLADFGVAGQL 169
Query 61 SD---KDEEFAGTPQWMAPEV 78
+D K F GTP WMAPEV
Sbjct 170 TDTQIKRNTFVGTPFWMAPEV 190
> ath:AT1G70430 protein kinase family protein
Length=594
Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 41/85 (48%), Positives = 49/85 (57%), Gaps = 18/85 (21%)
Query 1 IIAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-V 59
IIA LL++VL ALVYLH ++ IHRD+KA NIL+ G KL DFG+S
Sbjct 115 IIATLLREVLKALVYLH-----------RQGHIHRDVKAGNILIHSKGVVKLGDFGVSAC 163
Query 60 LSDKDEE------FAGTPQWMAPEV 78
+ D E F GTP WMAPEV
Sbjct 164 MFDSGERMQTRNTFVGTPCWMAPEV 188
> dre:100005183 map4k3; mitogen-activated protein kinase kinase
kinase kinase 3; K04406 mitogen-activated protein kinase kinase
kinase kinase 3 [EC:2.7.11.1]
Length=897
Score = 67.8 bits (164), Expect = 8e-12, Method: Composition-based stats.
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA++ ++ L + YLH + GKI HRD+K ANILL+++G KL DFG I
Sbjct 113 IAYVCRETLQGVYYLHNK-----GKI------HRDIKGANILLTDNGYVKLADFGVSAQI 161
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
S K + F GTP WMAPEVA
Sbjct 162 SATLAKRKSFIGTPYWMAPEVA 183
> xla:447339 map4k5, MGC83247; mitogen-activated protein kinase
kinase kinase kinase 5 (EC:2.7.11.1); K08833 mitogen-activated
protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
Length=823
Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 36/82 (43%), Positives = 47/82 (57%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA++ ++ L L YLH R +HRD+K ANILL+++G KL DFG I
Sbjct 113 IAYMCRETLQGLAYLHSRAK-----------MHRDIKGANILLTDNGDVKLADFGVAAKI 161
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
+ K + F GTP WMAPEVA
Sbjct 162 TATIAKRKSFIGTPYWMAPEVA 183
> mmu:225028 Map4k3, 4833416M01Rik, 4833416M07Rik, 9530052P13Rik,
Glk, MAPKKKK3, RAB8IPL1; mitogen-activated protein kinase
kinase kinase kinase 3 (EC:2.7.11.1); K04406 mitogen-activated
protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
Length=896
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS--- 58
IA++ ++ L L YLH + GK+ HRD+K ANILL+++G KL DFG+S
Sbjct 113 IAYVSRETLQGLYYLHSK-----GKM------HRDIKGANILLTDNGHVKLADFGVSAQI 161
Query 59 -VLSDKDEEFAGTPQWMAPEVA 79
K + F GTP WMAPEVA
Sbjct 162 TATIAKRKSFIGTPYWMAPEVA 183
> hsa:8491 MAP4K3, GLK, MAPKKKK3, MEKKK_3, RAB8IPL1; mitogen-activated
protein kinase kinase kinase kinase 3 (EC:2.7.11.1);
K04406 mitogen-activated protein kinase kinase kinase kinase
3 [EC:2.7.11.1]
Length=894
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS--- 58
IA++ ++ L L YLH + GK+ HRD+K ANILL+++G KL DFG+S
Sbjct 113 IAYVSRETLQGLYYLHSK-----GKM------HRDIKGANILLTDNGHVKLADFGVSAQI 161
Query 59 -VLSDKDEEFAGTPQWMAPEVA 79
K + F GTP WMAPEVA
Sbjct 162 TATIAKRKSFIGTPYWMAPEVA 183
> dre:558281 mitogen-activated protein kinase kinase kinase kinase
3-like
Length=597
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS--- 58
IA++ ++ L L YLH + GK+ HRD+K ANILL+++G KL DFG+S
Sbjct 59 IAYVTRETLQGLYYLHNK-----GKM------HRDIKGANILLTDNGYVKLADFGVSAQI 107
Query 59 -VLSDKDEEFAGTPQWMAPEVA 79
K + F GTP WMAPEVA
Sbjct 108 TATLAKRKSFIGTPYWMAPEVA 129
> dre:561669 mitogen-activated protein kinase kinase kinase kinase
4-like
Length=1040
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 34/81 (41%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ ++VL L++LH V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYVCREVLRGLLHLHSHHV-----------IHRDIKGQNVLLTENAEIKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTIGRRNTFIGTPYWMAPEV 199
> hsa:50488 MINK1, B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK,
hMINKbeta; misshapen-like kinase 1 (EC:2.7.11.1); K04413
misshapen/NIK-related kinase [EC:2.7.11.1]
Length=1312
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLAHLHAHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> mmu:50932 Mink1, B55, MINK, Map4k6, RP23-122P1.6, Ysk2; misshapen-like
kinase 1 (zebrafish) (EC:2.7.11.1); K04413 misshapen/NIK-related
kinase [EC:2.7.11.1]
Length=1337
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLAHLHAHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> cel:ZC404.9 gck-2; Germinal Center Kinase family member (gck-2);
K08286 protein-serine/threonine kinase [EC:2.7.11.-]
Length=829
Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 40/82 (48%), Positives = 46/82 (56%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA + ++ L L YLH GKI HRD+K ANILLS SG KL DFG I
Sbjct 112 IAFVCRETLRGLNYLHNM-----GKI------HRDIKGANILLSSSGDVKLADFGVAAQI 160
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
+ K + F GTP WMAPEVA
Sbjct 161 TATIGKRKSFIGTPYWMAPEVA 182
> ath:AT5G14720 protein kinase family protein
Length=674
Score = 66.2 bits (160), Expect = 2e-11, Method: Composition-based stats.
Identities = 39/85 (45%), Positives = 47/85 (55%), Gaps = 18/85 (21%)
Query 1 IIAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-- 58
+IA LL++ L ALVYLH IHRD+KA NILL +G KL DFG+S
Sbjct 115 VIATLLRETLKALVYLHAHG-----------HIHRDVKAGNILLDSNGAVKLADFGVSAC 163
Query 59 VLSDKDEE-----FAGTPQWMAPEV 78
+ D + F GTP WMAPEV
Sbjct 164 MFDTGDRQRSRNTFVGTPCWMAPEV 188
> xla:414526 MGC81311, taok1-a; serine/threonine-protein kinase
TAO1-A (EC:2.7.11.1); K04429 thousand and one amino acid protein
kinase [EC:2.7.11.1]
Length=1001
Score = 66.2 bits (160), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHNL-----------IHRDIKAGNILLTEPGQVKLADFGSASIA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> dre:100333250 misshapen-like kinase 1-like; K04413 misshapen/NIK-related
kinase [EC:2.7.11.1]
Length=1273
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLSHLHAHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> mmu:216965 Taok1, 2810468K05Rik, AU020252, D130018F14Rik, MGC29021,
Map3k16, Markk, Psk2, mKIAA1361; TAO kinase 1 (EC:2.7.11.1);
K04429 thousand and one amino acid protein kinase [EC:2.7.11.1]
Length=1001
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHTM-----------IHRDIKAGNILLTEPGQVKLADFGSASMA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> hsa:57551 TAOK1, FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1;
TAO kinase 1 (EC:2.7.11.1); K04429 thousand and one amino
acid protein kinase [EC:2.7.11.1]
Length=1001
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHTM-----------IHRDIKAGNILLTEPGQVKLADFGSASMA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> dre:100004576 TAO kinase 1-like; K04429 thousand and one amino
acid protein kinase [EC:2.7.11.1]
Length=1023
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHNM-----------IHRDIKAGNILLTEPGQVKLADFGSASIA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> xla:446555 mink1, MGC81192, mink; misshapen-like kinase 1 (EC:2.7.11.1);
K04413 misshapen/NIK-related kinase [EC:2.7.11.1]
Length=1270
Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLSHLHAHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> dre:334565 map4k5, MGC55719, fl74c10, wu:fl74c10, zgc:55719,
zgc:55985; mitogen-activated protein kinase kinase kinase kinase
5 (EC:2.7.11.1); K08833 mitogen-activated protein kinase
kinase kinase kinase 5 [EC:2.7.11.1]
Length=878
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA++ ++ L L YLH + GK+ HRD+K ANILL+++G KL DFG I
Sbjct 117 IAYVCRETLQGLGYLHSK-----GKM------HRDIKGANILLTDNGDVKLADFGVAAKI 165
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
+ K + F GTP WMAPEVA
Sbjct 166 TATMAKRKSFIGTPYWMAPEVA 187
> mmu:53416 Stk39, AW227544, AW556857, DCHT, RF005, Rnl5, SPAK;
serine/threonine kinase 39, STE20/SPS1 homolog (yeast) (EC:2.7.11.1);
K08282 non-specific serine/threonine protein kinase
[EC:2.7.11.1]
Length=556
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 40/87 (45%), Positives = 49/87 (56%), Gaps = 20/87 (22%)
Query 1 IIAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-- 58
IIA +LK+VL L YLH + IHRDLKA NILL E G+ ++ DFG+S
Sbjct 180 IIATILKEVLEGLDYLH-----------RNGQIHRDLKAGNILLGEDGSVQIADFGVSAF 228
Query 59 ------VLSDK-DEEFAGTPQWMAPEV 78
V +K + F GTP WMAPEV
Sbjct 229 LATGGDVTRNKVRKTFVGTPCWMAPEV 255
> cel:ZC504.4 mig-15; abnormal cell MIGration family member (mig-15);
K08282 non-specific serine/threonine protein kinase
[EC:2.7.11.1]
Length=1072
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 34/81 (41%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL++S KL+DFG+S
Sbjct 128 IAYICREILRGLYHLHQSKV-----------IHRDIKGQNVLLTDSAEVKLVDFGVSAQL 176
Query 62 DKD----EEFAGTPQWMAPEV 78
DK F GTP WMAPEV
Sbjct 177 DKTVGRRNTFIGTPYWMAPEV 197
> dre:554108 zgc:112307
Length=868
Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHNM-----------IHRDIKAGNILLTEPGQVKLADFGSASIA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> dre:100334915 serine/threonine-protein kinase TAO1-like
Length=1001
Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 128 IAAITHGALQGLAYLHSHNM-----------IHRDIKAGNILLTEPGQVKLADFGSASIA 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> hsa:27347 STK39, DCHT, DKFZp686K05124, PASK, SPAK; serine threonine
kinase 39 (EC:2.7.11.1); K08282 non-specific serine/threonine
protein kinase [EC:2.7.11.1]
Length=545
Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 40/87 (45%), Positives = 49/87 (56%), Gaps = 20/87 (22%)
Query 1 IIAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGIS-- 58
IIA +LK+VL L YLH + IHRDLKA NILL E G+ ++ DFG+S
Sbjct 168 IIATILKEVLEGLDYLH-----------RNGQIHRDLKAGNILLGEDGSVQIADFGVSAF 216
Query 59 ------VLSDK-DEEFAGTPQWMAPEV 78
V +K + F GTP WMAPEV
Sbjct 217 LATGGDVTRNKVRKTFVGTPCWMAPEV 243
> dre:394150 oxsr1b, MGC55494, zgc:55494, zgc:77321; oxidative-stress
responsive 1b (EC:2.7.11.1); K08835 oxidative-stress
responsive protein 1 [EC:2.7.11.1]
Length=520
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 38/86 (44%), Positives = 46/86 (53%), Gaps = 20/86 (23%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVL- 60
IA +LK+VL L YLH K IHRDLKA NILL E G+ ++ DFG+S
Sbjct 123 IATVLKEVLQGLEYLH-----------KNGQIHRDLKAGNILLGEDGSVQIADFGVSAFL 171
Query 61 --------SDKDEEFAGTPQWMAPEV 78
+ + F GTP WMAPEV
Sbjct 172 ATGGDMTRNKVRKTFVGTPCWMAPEV 197
> mmu:665113 Tnik, 1500031A17Rik, 4831440I19Rik, AI451411, C530008O15Rik,
C630040K21Rik, KIAA0551, MGC189819, MGC189859; TRAF2
and NCK interacting kinase (EC:2.7.11.1); K08840 TRAF2
and NCK interacting kinase [EC:2.7.11.1]
Length=1352
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLSHLHQHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> hsa:23043 TNIK; TRAF2 and NCK interacting kinase (EC:2.7.11.1);
K08840 TRAF2 and NCK interacting kinase [EC:2.7.11.1]
Length=1352
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 15/81 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA++ +++L L +LH +V IHRD+K N+LL+E+ KL+DFG+S
Sbjct 130 IAYICREILRGLSHLHQHKV-----------IHRDIKGQNVLLTENAEVKLVDFGVSAQL 178
Query 62 DKD----EEFAGTPQWMAPEV 78
D+ F GTP WMAPEV
Sbjct 179 DRTVGRRNTFIGTPYWMAPEV 199
> hsa:11183 MAP4K5, GCKR, KHS, KHS1, MAPKKKK5; mitogen-activated
protein kinase kinase kinase kinase 5 (EC:2.7.11.1); K08833
mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
Length=846
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA++ ++ L L YLH + GK+ HRD+K ANILL++ G KL DFG I
Sbjct 117 IAYVCRETLQGLAYLHTK-----GKM------HRDIKGANILLTDHGDVKLADFGVAAKI 165
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
+ K + F GTP WMAPEVA
Sbjct 166 TATIAKRKSFIGTPYWMAPEVA 187
> cel:C09B8.7 pak-1; P21-Activated Kinase family member (pak-1);
K04409 p21-activated kinase 1 [EC:2.7.11.1]
Length=569
Score = 65.1 bits (157), Expect = 6e-11, Method: Composition-based stats.
Identities = 38/84 (45%), Positives = 46/84 (54%), Gaps = 15/84 (17%)
Query 1 IIAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG---- 56
IIA + ++VL AL +LH R V IHRD+K+ NILL G+ KL DFG
Sbjct 387 IIAAVCREVLQALEFLHSRHV-----------IHRDIKSDNILLGMDGSVKLTDFGFCAQ 435
Query 57 ISVLSDKDEEFAGTPQWMAPEVAT 80
+S K GTP WMAPEV T
Sbjct 436 LSPEQRKRTTMVGTPYWMAPEVVT 459
> mmu:399510 Map4k5, 4432415E19Rik, GCKR, KHS, MAPKKKK5; mitogen-activated
protein kinase kinase kinase kinase 5 (EC:2.7.11.1);
K08833 mitogen-activated protein kinase kinase kinase
kinase 5 [EC:2.7.11.1]
Length=847
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 15/82 (18%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFG----I 57
IA++ ++ L L YLH + GK+ HRD+K ANILL++ G KL DFG I
Sbjct 117 IAYVCRETLQGLAYLHTK-----GKM------HRDIKGANILLTDHGDVKLADFGVAAKI 165
Query 58 SVLSDKDEEFAGTPQWMAPEVA 79
+ K + F GTP WMAPEVA
Sbjct 166 TATIAKRKSFIGTPYWMAPEVA 187
> xla:446778 taok3, MGC80412; TAO kinase 3 (EC:2.7.11.1); K04429
thousand and one amino acid protein kinase [EC:2.7.11.1]
Length=896
Score = 64.7 bits (156), Expect = 6e-11, Method: Composition-based stats.
Identities = 36/80 (45%), Positives = 41/80 (51%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + S
Sbjct 124 IAAITHGALQGLAYLHSHNM-----------IHRDIKAGNILLTEPGQVKLADFGSASKS 172
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 173 SPANSFVGTPYWMAPEVILA 192
> xla:379165 taok1, MGC52943, taok1-b; TAO kinase 1 (EC:2.7.11.1);
K04429 thousand and one amino acid protein kinase [EC:2.7.11.1]
Length=1001
Score = 64.7 bits (156), Expect = 6e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + +
Sbjct 128 IAAITHGALQGLAYLHSHNL-----------IHRDIKAGNILLTEPGQVKLADFGSASIV 176
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 177 SPANSFVGTPYWMAPEVILA 196
> hsa:51347 TAOK3, DKFZp666H245, DPK, FLJ31808, JIK, MAP3K18;
TAO kinase 3 (EC:2.7.11.1); K04429 thousand and one amino acid
protein kinase [EC:2.7.11.1]
Length=898
Score = 64.7 bits (156), Expect = 6e-11, Method: Composition-based stats.
Identities = 35/80 (43%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query 2 IAHLLKDVLSALVYLHGREVGPEGKIKKEVCIHRDLKAANILLSESGTAKLIDFGISVLS 61
IA + L L YLH + IHRD+KA NILL+E G KL DFG + ++
Sbjct 124 IAAITHGALHGLAYLHSHAL-----------IHRDIKAGNILLTEPGQVKLADFGSASMA 172
Query 62 DKDEEFAGTPQWMAPEVATA 81
F GTP WMAPEV A
Sbjct 173 SPANSFVGTPYWMAPEVILA 192
Lambda K H
0.319 0.137 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2030857360
Database: egene_temp_file_orthology_annotation_similarity_blast_database_966
Posted date: Sep 16, 2011 8:45 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40