bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0198_orf2
Length=141
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_042380 elongation of very long chain fatty acids 4 ... 177 1e-44
pfa:PFF0290w long chain polyunsaturated fatty acid elongation ... 119 3e-27
xla:734428 hypothetical protein MGC115163; K10249 elongation o... 97.4 1e-20
dre:335732 elovl4b, elovl4, wu:fk62b04, zgc:73054; elongation ... 94.4 1e-19
dre:554145 im:7139490; zgc:112263; K10249 elongation of very l... 93.6 2e-19
dre:767653 MGC153394; zgc:153394 91.7 6e-19
dre:334217 elovl7a, MGC174838, elovl7, fi36f02, wu:fi36f02, zg... 89.4 3e-18
dre:327274 elovl7b, elovl1, wu:fd20a06, zgc:56422; ELOVL famil... 88.2 7e-18
dre:100332451 elongation of very long chain fatty acids-like 4... 87.4 1e-17
dre:393769 elovl4a, MGC73341, zgc:73341; elongation of very lo... 87.4 1e-17
xla:398440 elovl7; ELOVL family member 7, elongation of long c... 87.0 2e-17
xla:432300 hypothetical protein MGC80262; K10250 elongation of... 87.0 2e-17
dre:449816 elovl1a, zgc:103538; elongation of very long chain ... 85.5 5e-17
hsa:79993 ELOVL7, FLJ23563; ELOVL family member 7, elongation ... 84.3 1e-16
hsa:6785 ELOVL4, ADMD, CT118, FLJ17667, FLJ92876, STGD2, STGD3... 83.2 2e-16
dre:406725 elovl1b, wu:fj32h05, zgc:56567; elongation of very ... 82.0 6e-16
mmu:83603 Elovl4; elongation of very long chain fatty acids (F... 81.6 8e-16
xla:379510 hypothetical protein MGC64517; K10247 elongation of... 81.3 8e-16
mmu:74559 Elovl7, 9130013K24Rik, AI840082; ELOVL family member... 80.9 1e-15
dre:678614 elovl2, MGC136352, MGC158526, zgc:136352; elongatio... 80.5 2e-15
xla:734950 elovl5, MGC131143; ELOVL family member 5, elongatio... 79.0 5e-15
xla:380063 elovl1, MGC52731; elongation of very long chain fat... 78.6 5e-15
mmu:54325 Elovl1, AA407424, BB151133, Ssc1; elongation of very... 78.2 7e-15
xla:734710 hypothetical protein MGC114802; K10244 elongation o... 77.8 1e-14
dre:393425 elovl5, MGC63549, zgc:63549; ELOVL family member 5,... 76.6 2e-14
mmu:54326 Elovl2, AI317360, Ssc2; elongation of very long chai... 75.9 4e-14
hsa:64834 ELOVL1, Ssc1; elongation of very long chain fatty ac... 75.9 4e-14
hsa:60481 ELOVL5, HELO1, dJ483K16.1; ELOVL family member 5, el... 75.5 5e-14
xla:447388 elovl2, MGC84669; elongation of very long chain fat... 74.7 7e-14
hsa:54898 ELOVL2, FLJ20334, SSC2; elongation of very long chai... 74.7 8e-14
mmu:68801 Elovl5, 1110059L23Rik, AI747313, AU043003, HELO1; EL... 74.7 9e-14
tgo:TGME49_005350 fatty acid elongation protein, putative 68.6 5e-12
sce:YJL196C ELO1; Elo1p; K10245 fatty acid elongase 2 [EC:2.3.... 64.3 1e-10
cel:Y53F4B.2 elo-9; fatty acid ELOngation family member (elo-9) 61.6 7e-10
hsa:83401 ELOVL3, CIG-30, CIG30, MGC21435; elongation of very ... 61.2 1e-09
ath:AT3G06460 GNS1/SUR4 membrane family protein 59.3 4e-09
cel:D2024.3 elo-3; fatty acid ELOngation family member (elo-3) 58.9 4e-09
sce:YLR372W SUR4, APA1, ELO3, SRE1, VBM1; Elongase, involved i... 57.8 9e-09
pfa:PFA_0455c fatty acid elongation protein, GNS1/SUR4 family,... 57.8 9e-09
cel:F56H11.4 elo-1; fatty acid ELOngation family member (elo-1) 57.4 1e-08
ath:AT3G06470 GNS1/SUR4 membrane family protein 56.2 3e-08
cpv:cgd8_4630 7 pass integral membrane proteinwith FLHWFHH mot... 55.1 7e-08
cel:F11E6.5 elo-2; fatty acid ELOngation family member (elo-2) 54.3 1e-07
sce:YCR034W FEN1, ELO2, GNS1, VBM2; Fatty acid elongase, invol... 53.1 3e-07
dre:317738 elovl6, cb618, lce, zgc:73089; ELOVL family member ... 52.0 6e-07
cel:F41H10.7 elo-5; fatty acid ELOngation family member (elo-5) 51.2 1e-06
hsa:79071 ELOVL6, FACE, FAE, FLJ23378, LCE, MGC5487; ELOVL fam... 50.4 2e-06
mmu:12686 Elovl3, CIN-2, Cig30; elongation of very long chain ... 50.4 2e-06
mmu:170439 Elovl6, C77826, FAE, LCE, MGC107467; ELOVL family m... 50.4 2e-06
tgo:TGME49_053880 GNS1/SUR4 family domain-containing protein 49.7 3e-06
> tgo:TGME49_042380 elongation of very long chain fatty acids
4 protein, putative ; K10249 elongation of very long chain fatty
acids protein 4
Length=350
Score = 177 bits (448), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 78/140 (55%), Positives = 103/140 (73%), Gaps = 0/140 (0%)
Query 2 VWRAEEYSFMCNRFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHS 61
V+ AE Y+ + N+F+ MAE+ W FY+ K VDLLDTVF++ RG W Q SFLH+YHH+
Sbjct 154 VYVAEGYTIVFNKFDPSRRNMAEIVWLFYLTKVVDLLDTVFIVCRGKWAQFSFLHIYHHA 213
Query 62 SVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQ 121
S++Y+ WVNASVGYDG+IY+ VA N +HVVMYAYY MASLN AR +K F+T++QM Q
Sbjct 214 SILYMMWVNASVGYDGDIYFAVAANGAIHVVMYAYYLMASLNIGAARYIKPFITRMQMTQ 273
Query 122 FLSMTAHACYHVYYYKTCRY 141
FL M YH+ +Y+ C+Y
Sbjct 274 FLGMLGQGFYHICFYQDCQY 293
> pfa:PFF0290w long chain polyunsaturated fatty acid elongation
enzyme, putative
Length=293
Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 58/138 (42%), Positives = 82/138 (59%), Gaps = 0/138 (0%)
Query 4 RAEEYSFMCNRFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
+ +S N + +A W FY+ K VD +DT+ +++R W Q +FLHVYHH SV
Sbjct 121 KNRRFSLFYNSVDFSKKNIALCCWLFYLNKLVDFVDTILIVLRKKWNQFTFLHVYHHLSV 180
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
I WVN SVGYDG+IYY++ +N+ VH VMY YY+++S+ + K VT LQM QFL
Sbjct 181 FLIMWVNTSVGYDGDIYYIIVVNSFVHFVMYLYYYLSSVKFKVPIFAKACVTYLQMLQFL 240
Query 124 SMTAHACYHVYYYKTCRY 141
S+ Y ++ C Y
Sbjct 241 SIILPGFYVLFVRHYCPY 258
> xla:734428 hypothetical protein MGC115163; K10249 elongation
of very long chain fatty acids protein 4
Length=265
Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 48/132 (36%), Positives = 82/132 (62%), Gaps = 6/132 (4%)
Query 8 YSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
YS++C + N+ RMA V W+F+ K ++LLDT+F I+R + Q+SFLHVYHH+++
Sbjct 92 YSYLCQPVDYSNSELGMRMARVCWWFFFSKVIELLDTIFFIMRKKFNQISFLHVYHHATM 151
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
I+ W G+ +++ LN+ VH+ MY YY +A L + + + K ++T LQ+ Q
Sbjct 152 IFNWWAGVKYVAGGQAFFIGMLNSFVHIFMYLYYGLAVLGPKMQKYLWWKRYLTLLQLTQ 211
Query 122 FLSMTAHACYHV 133
F ++ H+ Y++
Sbjct 212 FGAIALHSSYNL 223
> dre:335732 elovl4b, elovl4, wu:fk62b04, zgc:73054; elongation
of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like
4b; K10249 elongation of very long chain fatty acids
protein 4
Length=303
Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 49/137 (35%), Positives = 79/137 (57%), Gaps = 6/137 (4%)
Query 4 RAEEYSFMCNRFNVPN----TRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYH 59
RA YS++C N N R+A W++Y+ K V+ LDTVF I+R + QVSFLHVYH
Sbjct 91 RAAGYSYLCQPVNYSNDVNEVRIASALWWYYISKGVEFLDTVFFIMRKKFNQVSFLHVYH 150
Query 60 HSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQL 117
H ++ + W+ G+ ++ +N+ +HV+MY YY +A+ + + + K ++T +
Sbjct 151 HCTMFILWWIGIKWVPGGQSFFGATINSGIHVLMYGYYGLAAFGPKIQKYLWWKKYLTII 210
Query 118 QMAQFLSMTAHACYHVY 134
QM QF HA + +Y
Sbjct 211 QMIQFHVTIGHAAHSLY 227
> dre:554145 im:7139490; zgc:112263; K10249 elongation of very
long chain fatty acids protein 4
Length=264
Score = 93.6 bits (231), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 6/134 (4%)
Query 7 EYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSS 62
YS++C + + RMA V W+F+ K ++L DTVF I+R Q++FLHVYHH +
Sbjct 91 NYSYLCQPVDYSTSPLGMRMANVCWWFFFSKVIELSDTVFFILRKKNSQLTFLHVYHHGT 150
Query 63 VIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMA 120
+I+ W G+ +++ LN VH+ MY+YY +A+L L + + K ++T LQ+
Sbjct 151 MIFNWWAGVKYVAGGQSFFIGLLNTFVHIWMYSYYGLAALGPHLQKYLWWKRYLTSLQLV 210
Query 121 QFLSMTAHACYHVY 134
QF+ +T H Y+++
Sbjct 211 QFILLTVHTGYNLF 224
> dre:767653 MGC153394; zgc:153394
Length=268
Score = 91.7 bits (226), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 49/134 (36%), Positives = 77/134 (57%), Gaps = 6/134 (4%)
Query 7 EYSFMCNRF----NVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSS 62
YS +C N RMA V W+FY K ++L DT+F I+R Q++FLHVYHH +
Sbjct 95 SYSLLCQPVDYTENPLPMRMARVCWWFYFSKVIELADTMFFILRKKNNQLTFLHVYHHGT 154
Query 63 VIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMA 120
+I+ W G+ + + +N+ VHVVMY YY +A+L + + + K ++T LQ+
Sbjct 155 MIFNWWAGVKYVAGGQSFLIGLINSFVHVVMYMYYGLAALGPQMQKYLWWKRYLTSLQLL 214
Query 121 QFLSMTAHACYHVY 134
QF +T H +++Y
Sbjct 215 QFFIVTIHTAFNLY 228
> dre:334217 elovl7a, MGC174838, elovl7, fi36f02, wu:fi36f02,
zgc:55879; ELOVL family member 7, elongation of long chain fatty
acids (yeast) a; K10250 elongation of very long chain fatty
acids protein 7
Length=288
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 48/143 (33%), Positives = 78/143 (54%), Gaps = 7/143 (4%)
Query 5 AEEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
Y+F C+ + + RMA V W +Y K++ +LDTVF ++R +Q++FLHV+HH
Sbjct 92 GTGYTFGCDLVDYSQSPKAMRMASVCWLYYFSKFIVMLDTVFFVLRKKPKQITFLHVFHH 151
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
S + + W G + LN +VHV+MY YY +++L R + K +T LQ
Sbjct 152 SIMPFTWWFGVRFSPGGLGTFHALLNCIVHVIMYTYYLLSALGPSFQRFLWWKKHLTSLQ 211
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ +T H + ++ K C Y
Sbjct 212 LIQFVLVTVHISQY-FFMKDCPY 233
> dre:327274 elovl7b, elovl1, wu:fd20a06, zgc:56422; ELOVL family
member 7, elongation of long chain fatty acids (yeast) b;
K10250 elongation of very long chain fatty acids protein 7
Length=282
Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 48/143 (33%), Positives = 81/143 (56%), Gaps = 7/143 (4%)
Query 5 AEEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
A Y++ C+ + ++ RMA W +Y K++++LDTVF ++R QVSFLHVYHH
Sbjct 92 ANGYTYRCDLVDYSSSPQALRMAWTCWLYYFSKFIEMLDTVFFVLRKKSSQVSFLHVYHH 151
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
S + + W G + LN +VHV+MY+YY +++L + + K ++T +Q
Sbjct 152 SIMPFTWWFGVRFAPGGLGTFHALLNCIVHVIMYSYYLLSALGPKYQKYLWWKKYMTTIQ 211
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ +TAH ++ + C Y
Sbjct 212 LVQFVLVTAHIG-QFFFMQDCPY 233
> dre:100332451 elongation of very long chain fatty acids-like
4-like
Length=298
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/137 (34%), Positives = 78/137 (56%), Gaps = 6/137 (4%)
Query 4 RAEEYSFMCNRFN---VPNT-RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYH 59
RA YS++C + PN R+A W++++ K V+ LDTVF I+R + Q+SFLHVYH
Sbjct 80 RAANYSYICQPVDYSDDPNEVRVAAALWWYFISKGVEYLDTVFFILRKKFNQISFLHVYH 139
Query 60 HSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQL 117
H ++ + W+ G+ ++ +NA +HV+MY YY +A+ + + + K ++T +
Sbjct 140 HCTMFTLWWIGIKWVAGGQSFFGAHMNAAIHVLMYLYYGLAAFGPKIQKFLWWKKYLTII 199
Query 118 QMAQFLSMTAHACYHVY 134
QM QF H +Y
Sbjct 200 QMVQFHVTIGHTALSLY 216
> dre:393769 elovl4a, MGC73341, zgc:73341; elongation of very
long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a;
K10249 elongation of very long chain fatty acids protein 4
Length=309
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 47/137 (34%), Positives = 78/137 (56%), Gaps = 6/137 (4%)
Query 4 RAEEYSFMCNRFN---VPNT-RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYH 59
RA YS++C + PN R+A W++++ K V+ LDTVF I+R + Q+SFLHVYH
Sbjct 91 RAANYSYICQPVDYSDDPNEVRVAAALWWYFISKGVEYLDTVFFILRKKFNQISFLHVYH 150
Query 60 HSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQL 117
H ++ + W+ G+ ++ +NA +HV+MY YY +A+ + + + K ++T +
Sbjct 151 HCTMFTLWWIGIKWVAGGQSFFGAHMNAAIHVLMYLYYGLAAFGPKIQKFLWWKKYLTII 210
Query 118 QMAQFLSMTAHACYHVY 134
QM QF H +Y
Sbjct 211 QMVQFHVTIGHTALSLY 227
> xla:398440 elovl7; ELOVL family member 7, elongation of long
chain fatty acids; K10250 elongation of very long chain fatty
acids protein 7
Length=302
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 79/143 (55%), Gaps = 7/143 (4%)
Query 5 AEEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
A YSF C+ + + RMA W FY K+++LLDTVF ++R Q++FLHVYHH
Sbjct 92 ATGYSFRCDIVDYSQSPQALRMAWTCWLFYFSKFIELLDTVFFVLRKKNSQITFLHVYHH 151
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
S + + W G + +N +VHV+MY+YY +++L + + K ++T +Q
Sbjct 152 SIMPWTWWFGVKFAPGGLGTFHALVNCVVHVIMYSYYGLSALGPAYQKYLWWKKYMTSIQ 211
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QFL +T H ++ + C Y
Sbjct 212 LTQFLMVTFHIG-QFFFMENCPY 233
> xla:432300 hypothetical protein MGC80262; K10250 elongation
of very long chain fatty acids protein 7
Length=301
Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 79/143 (55%), Gaps = 7/143 (4%)
Query 5 AEEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
A YSF C+ + + RMA W FY K+++LLDTVF ++R Q++FLHVYHH
Sbjct 92 ATGYSFRCDIVDYSRSPQALRMAWTCWLFYFSKFIELLDTVFFVLRKKNSQITFLHVYHH 151
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
S + + W G + +N +VHV+MY+YY +++L + + K ++T +Q
Sbjct 152 SIMPWTWWFGVKFAAGGLGTFHALVNCVVHVIMYSYYGLSALGPAYQKYLWWKKYMTSIQ 211
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QFL +T H ++ + C Y
Sbjct 212 LTQFLMVTFHIG-QFFFMENCPY 233
> dre:449816 elovl1a, zgc:103538; elongation of very long chain
fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1a
Length=315
Score = 85.5 bits (210), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query 2 VWRAEEYSFMCNRFNVPNT-RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
WR + +C+ + P RM W FY KY++LLDTVF ++R QV+FLH++HH
Sbjct 95 TWRCD----LCDPSSSPQALRMVRAAWLFYFSKYIELLDTVFFVLRKKHSQVTFLHIFHH 150
Query 61 SSVIYISWVNASVGYDGEIYYVVAL-NALVHVVMYAYYFMASLNSPLARMV--KIFVTQL 117
S + + W ++ G + AL NA VHV+MY YY +A+ + + K ++T +
Sbjct 151 SVLPWTWWWGITLTPAGGMGSFHALVNACVHVIMYTYYGLAAAGPRFQKYLWWKKYMTAI 210
Query 118 QMAQFLSMTAHACYHVYYYKTCRY 141
Q+ QF+ +T H + Y+ + C Y
Sbjct 211 QLIQFVLVTGHISQY-YFMEKCDY 233
> hsa:79993 ELOVL7, FLJ23563; ELOVL family member 7, elongation
of long chain fatty acids (yeast); K10250 elongation of very
long chain fatty acids protein 7
Length=281
Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 46/140 (32%), Positives = 77/140 (55%), Gaps = 7/140 (5%)
Query 8 YSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
YSF C+ + + RMA W +Y K+++LLDT+F ++R QV+FLHV+HH+ +
Sbjct 95 YSFRCDIVDYSRSPTALRMARTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHHTIM 154
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
+ W G + LN VHVVMY+YY +++L + + K ++T LQ+ Q
Sbjct 155 PWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQ 214
Query 122 FLSMTAHACYHVYYYKTCRY 141
F+ + H ++ + C+Y
Sbjct 215 FVIVAIHIS-QFFFMEDCKY 233
> hsa:6785 ELOVL4, ADMD, CT118, FLJ17667, FLJ92876, STGD2, STGD3;
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3,
yeast)-like 4; K10249 elongation of very long chain
fatty acids protein 4
Length=314
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 45/133 (33%), Positives = 74/133 (55%), Gaps = 6/133 (4%)
Query 8 YSFMCNRF----NVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
YS++C NV R+A W++++ K V+ LDTVF I+R QVSFLHVYHH ++
Sbjct 106 YSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTM 165
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
+ W+ G+ ++ LN+ +HV+MY+YY + + + + + K ++T LQ+ Q
Sbjct 166 FTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLIQ 225
Query 122 FLSMTAHACYHVY 134
F H +Y
Sbjct 226 FHVTIGHTALSLY 238
> dre:406725 elovl1b, wu:fj32h05, zgc:56567; elongation of very
long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like
1b; K10247 elongation of very long chain fatty acids protein
1
Length=320
Score = 82.0 bits (201), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 44/143 (30%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Query 2 VWRAEEYSFMCNRFNVPNT-RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
WR + C+ N P RMA V W F K+++L+DTVF ++R Q++FLH++HH
Sbjct 95 TWRCDP----CDYSNSPQGLRMARVAWLFLFSKFIELMDTVFFVLRKKHSQITFLHIFHH 150
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
S + + W S+ G + +N+ VHV+MY YY +++ + + K ++T +Q
Sbjct 151 SFMPWTWWWGVSIVPGGMGSFHAMVNSCVHVIMYFYYGLSAAGPRFQKFLWWKKYMTAIQ 210
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ ++ H Y+ ++C +
Sbjct 211 LTQFVLVSLHVS-QWYFMESCDF 232
> mmu:83603 Elovl4; elongation of very long chain fatty acids
(FEN1/Elo2, SUR4/Elo3, yeast)-like 4; K10249 elongation of very
long chain fatty acids protein 4
Length=312
Score = 81.6 bits (200), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 6/133 (4%)
Query 8 YSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
YS++C + N R+A W++++ K V+ LDTVF I+R QVSFLHVYHH ++
Sbjct 106 YSYICQSVDYSNDVNEVRIAGALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTM 165
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
+ W+ G+ ++ +N+ +HV+MY+YY + + + + + K ++T LQ+ Q
Sbjct 166 FTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLVQ 225
Query 122 FLSMTAHACYHVY 134
F H +Y
Sbjct 226 FHVTIGHTALSLY 238
> xla:379510 hypothetical protein MGC64517; K10247 elongation
of very long chain fatty acids protein 1
Length=290
Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 45/140 (32%), Positives = 78/140 (55%), Gaps = 7/140 (5%)
Query 8 YSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
Y++ C+ +V + RM +V W F K+++LLDTVF +VR Q++FLH+ HHS +
Sbjct 93 YTWRCDPVDVSDKPMALRMVQVAWLFLFSKFIELLDTVFFVVRKKNSQITFLHIIHHSVL 152
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
+ W G G + +N+LVHV+MY YY +++ + + K +T +Q+ Q
Sbjct 153 PWSWWWGVKFGPGGMGSFHAMINSLVHVIMYFYYGLSAAGPRFQKYLWWKKHMTAIQLIQ 212
Query 122 FLSMTAHACYHVYYYKTCRY 141
F+ ++ H + Y+ +C Y
Sbjct 213 FVLVSIHISQY-YFMPSCDY 231
> mmu:74559 Elovl7, 9130013K24Rik, AI840082; ELOVL family member
7, elongation of long chain fatty acids (yeast); K10250 elongation
of very long chain fatty acids protein 7
Length=281
Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 45/143 (31%), Positives = 75/143 (52%), Gaps = 7/143 (4%)
Query 5 AEEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHH 60
YSF C+ + + RM W +Y K+++LLDT+F ++R QV+FLHV+HH
Sbjct 92 GTGYSFRCDIVDYSQSPRAMRMVHTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHH 151
Query 61 SSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQ 118
+ + + W G + LN VHVVMY+YY + ++ + + K +T LQ
Sbjct 152 TIMPWTWWFGVKFAAGGLGTFHAFLNTAVHVVMYSYYGLCAMGPAYQKYLWWKKHLTSLQ 211
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ +T H +++ + C Y
Sbjct 212 LVQFVLVTIHIG-QIFFMEDCNY 233
> dre:678614 elovl2, MGC136352, MGC158526, zgc:136352; elongation
of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like
2; K10205 elongation of very long chain fatty acids
protein 2 [EC:2.3.1.-]
Length=260
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 46/132 (34%), Positives = 77/132 (58%), Gaps = 5/132 (3%)
Query 2 VWRAEEYSFMC---NRFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVY 58
VW A Y C + + R+A+V W++Y K ++ LDT+F+++R Q+SFLHVY
Sbjct 90 VWSAG-YRLQCQALDEVGEADIRVAKVLWWYYFSKLIEFLDTIFIVLRKKNSQISFLHVY 148
Query 59 HHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQL 117
HH+S+ I W + G+ ++ LN+ +HV+MY+YY +A++ S + K ++TQ
Sbjct 149 HHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHVLMYSYYGLATIPSMHKYLWWKRYLTQA 208
Query 118 QMAQFLSMTAHA 129
Q+ QF+ H
Sbjct 209 QLVQFVLTITHT 220
> xla:734950 elovl5, MGC131143; ELOVL family member 5, elongation
of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like); K10244
elongation of very long chain fatty acids protein 5 [EC:2.3.1.-]
Length=295
Score = 79.0 bits (193), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 47/137 (34%), Positives = 77/137 (56%), Gaps = 10/137 (7%)
Query 1 DVWRAEEYSFMCN---RFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHV 57
VW Y+F C +T++ V W++Y K ++ +DT F I+R N Q++ LHV
Sbjct 86 GVWEGG-YNFFCQDTHSGGDADTKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHV 144
Query 58 YHHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV---KIFV 114
YHH+S++ I W + G ++ LN+ +HV+MY+YY ++++ P R K ++
Sbjct 145 YHHASMLNIWWFVMNWVPCGHSFFGATLNSFIHVLMYSYYGLSAI--PAIRPYLWWKKYI 202
Query 115 TQLQMAQF-LSMTAHAC 130
TQ Q+ QF L+MT C
Sbjct 203 TQCQLTQFVLTMTQTTC 219
> xla:380063 elovl1, MGC52731; elongation of very long chain fatty
acids (FEN1/Elo2, SUR4/Elo3)-like 1; K10247 elongation
of very long chain fatty acids protein 1
Length=290
Score = 78.6 bits (192), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 44/140 (31%), Positives = 77/140 (55%), Gaps = 7/140 (5%)
Query 8 YSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSV 63
Y++ C+ +V ++ RM V W F K+++LLDTV +VR Q++FLH++HHS +
Sbjct 93 YTWRCDPVDVSDSPMALRMVRVAWLFLFSKFIELLDTVLFVVRKKNGQITFLHIFHHSVL 152
Query 64 IYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV--KIFVTQLQMAQ 121
W G G + +N+LVHV+MY YY +++ + + K +T +Q+ Q
Sbjct 153 PCSWWWGVKFGPGGMGSFHAMINSLVHVIMYFYYGLSAAGPRFQKYLWWKKHMTAIQLIQ 212
Query 122 FLSMTAHACYHVYYYKTCRY 141
F+ ++ H + Y+ +C Y
Sbjct 213 FVLVSIHITQY-YFMPSCDY 231
> mmu:54325 Elovl1, AA407424, BB151133, Ssc1; elongation of very
long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like
1; K10247 elongation of very long chain fatty acids protein
1
Length=202
Score = 78.2 bits (191), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 47/143 (32%), Positives = 79/143 (55%), Gaps = 9/143 (6%)
Query 6 EEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHS 61
Y++ C+ + N+ RM V W F + K ++L+DTV I+R QV+FLHV+HHS
Sbjct 10 STYTWRCDPIDFSNSPEALRMVRVAWLFMLSKVIELMDTVIFILRKKDGQVTFLHVFHHS 69
Query 62 SVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV---KIFVTQLQ 118
+ + W + G + +N+ VHVVMY YY +++L P+A+ K +T +Q
Sbjct 70 VLPWSWWWGIKIAPGGMGSFHAMINSSVHVVMYLYYGLSALG-PVAQPYLWWKKHMTAIQ 128
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ ++ H + Y+ +C Y
Sbjct 129 LIQFVLVSLHISQY-YFMPSCNY 150
> xla:734710 hypothetical protein MGC114802; K10244 elongation
of very long chain fatty acids protein 5 [EC:2.3.1.-]
Length=295
Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 49/148 (33%), Positives = 81/148 (54%), Gaps = 13/148 (8%)
Query 1 DVWRAEEYSFMCN---RFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHV 57
VW Y+F C +T++ V W++Y K ++ +DT F I+R N Q++ LHV
Sbjct 86 GVWEGG-YNFFCQDTHSGGDADTKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQMTVLHV 144
Query 58 YHHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV---KIFV 114
YHH+S+ I W + G Y+ LN+ +HV+MY+YY ++++ P R K ++
Sbjct 145 YHHASMPNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSAI--PAIRPYLWWKKYI 202
Query 115 TQLQMAQF-LSMTAHACYHVYYYKTCRY 141
TQ Q+ QF L+MT C ++ C++
Sbjct 203 TQCQLTQFVLTMTQTTCAMIW---PCKF 227
> dre:393425 elovl5, MGC63549, zgc:63549; ELOVL family member
5, elongation of long chain fatty acids (yeast); K10244 elongation
of very long chain fatty acids protein 5 [EC:2.3.1.-]
Length=291
Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 45/130 (34%), Positives = 75/130 (57%), Gaps = 9/130 (6%)
Query 8 YSFMCNRFNV---PNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVI 64
Y+F C + + RM V W++Y K ++ +DT F I+R N Q++FLHVYHH++++
Sbjct 92 YNFFCQNTHSGGDADNRMMNVLWWYYFSKLIEFMDTFFFILRKNNHQITFLHVYHHATML 151
Query 65 YISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV---KIFVTQLQMAQ 121
I W + G Y+ N+ +HV+MY+YY ++++ P R K ++TQ Q+ Q
Sbjct 152 NIWWFVMNWVPCGHSYFGATFNSFIHVLMYSYYGLSAV--PALRPYLWWKKYITQGQLVQ 209
Query 122 F-LSMTAHAC 130
F L+M +C
Sbjct 210 FVLTMFQTSC 219
> mmu:54326 Elovl2, AI317360, Ssc2; elongation of very long chain
fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2; K10205
elongation of very long chain fatty acids protein 2 [EC:2.3.1.-]
Length=292
Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 44/138 (31%), Positives = 76/138 (55%), Gaps = 6/138 (4%)
Query 8 YSFMCNRFNVP---NTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVI 64
Y+ C + + R+A+V W++Y K V+ LDT+F ++R Q++FLHVYHH+S+
Sbjct 95 YNLQCQNLDSAGEGDVRVAKVLWWYYFSKLVEFLDTIFFVLRKKTNQITFLHVYHHASMF 154
Query 65 YISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQLQMAQFL 123
I W + G+ ++ LN+ +H++MY+YY ++ S + K ++TQ Q+ QF+
Sbjct 155 NIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFV 214
Query 124 SMTAHACYHVYYYKTCRY 141
H V K C +
Sbjct 215 LTITHTLSAV--VKPCGF 230
> hsa:64834 ELOVL1, Ssc1; elongation of very long chain fatty
acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; K10247 elongation
of very long chain fatty acids protein 1
Length=279
Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 45/143 (31%), Positives = 78/143 (54%), Gaps = 9/143 (6%)
Query 6 EEYSFMCNRFNVPNT----RMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHS 61
Y++ C+ + N+ RM V W F K+++L+DTV I+R QV+FLHV+HHS
Sbjct 87 STYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLHVFHHS 146
Query 62 SVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMV---KIFVTQLQ 118
+ + W + G + +N+ VHV+MY YY +++ P+A+ K +T +Q
Sbjct 147 VLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFG-PVAQPYLWWKKHMTAIQ 205
Query 119 MAQFLSMTAHACYHVYYYKTCRY 141
+ QF+ ++ H + Y+ +C Y
Sbjct 206 LIQFVLVSLHISQY-YFMSSCNY 227
> hsa:60481 ELOVL5, HELO1, dJ483K16.1; ELOVL family member 5,
elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like,
yeast); K10244 elongation of very long chain fatty acids
protein 5 [EC:2.3.1.-]
Length=299
Score = 75.5 bits (184), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 45/135 (33%), Positives = 77/135 (57%), Gaps = 6/135 (4%)
Query 1 DVWRAEEYSFMCNRFNV---PNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHV 57
VW + Y+F C + ++ V W++Y K ++ +DT F I+R N Q++ LHV
Sbjct 86 GVWEGK-YNFFCQGTRTAGESDMKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHV 144
Query 58 YHHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQ 116
YHH+S++ I W + G Y+ LN+ +HV+MY+YY ++S+ S + K ++TQ
Sbjct 145 YHHASMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSVPSMRPYLWWKKYITQ 204
Query 117 LQMAQF-LSMTAHAC 130
Q+ QF L++ +C
Sbjct 205 GQLLQFVLTIIQTSC 219
> xla:447388 elovl2, MGC84669; elongation of very long chain fatty
acids (FEN1/Elo2, SUR4/Elo3)-like 2; K10205 elongation
of very long chain fatty acids protein 2 [EC:2.3.1.-]
Length=296
Score = 74.7 bits (182), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 40/126 (31%), Positives = 73/126 (57%), Gaps = 4/126 (3%)
Query 8 YSFMCNRFNVP---NTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVI 64
Y+ C + + R+A+V W++Y K ++ +DT+F ++R Q++FLHVYHH+++
Sbjct 95 YNLQCQNLDSAGEADVRVAKVLWWYYFSKAIEFMDTIFFVLRKKNSQITFLHVYHHATMF 154
Query 65 YISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQLQMAQFL 123
I W + G+ ++ LN+ +HV+MY+YY ++ + S + K ++TQ Q+ QFL
Sbjct 155 NIWWCVLNWIPCGQSFFGPTLNSFIHVLMYSYYGLSVIPSMHKYLWWKKYLTQAQLVQFL 214
Query 124 SMTAHA 129
H
Sbjct 215 LTITHT 220
> hsa:54898 ELOVL2, FLJ20334, SSC2; elongation of very long chain
fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2; K10205
elongation of very long chain fatty acids protein 2 [EC:2.3.1.-]
Length=296
Score = 74.7 bits (182), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 42/124 (33%), Positives = 72/124 (58%), Gaps = 3/124 (2%)
Query 19 NTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGE 78
+ R+A+V W++Y K V+ LDT+F ++R Q++FLHVYHH+S+ I W + G+
Sbjct 109 DIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQ 168
Query 79 IYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQLQMAQFLSMTAHACYHVYYYK 137
++ LN+ +H++MY+YY ++ S + K ++TQ Q+ QF+ H V K
Sbjct 169 SFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTITHTMSAV--VK 226
Query 138 TCRY 141
C +
Sbjct 227 PCGF 230
> mmu:68801 Elovl5, 1110059L23Rik, AI747313, AU043003, HELO1;
ELOVL family member 5, elongation of long chain fatty acids
(yeast); K10244 elongation of very long chain fatty acids protein
5 [EC:2.3.1.-]
Length=299
Score = 74.7 bits (182), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Query 1 DVWRAEEYSFMCN---RFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHV 57
VW + Y+F C + ++ V W++Y K ++ +DT F I+R N Q++ LHV
Sbjct 86 GVWEGK-YNFFCQGTRSAGESDMKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHV 144
Query 58 YHHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARM-VKIFVTQ 116
YHH++++ I W + G Y+ LN+ +HV+MY+YY ++S+ S + K ++TQ
Sbjct 145 YHHATMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSIPSMRPYLWWKKYITQ 204
Query 117 LQMAQF-LSMTAHAC 130
Q+ QF L++ C
Sbjct 205 GQLVQFVLTIIQTTC 219
> tgo:TGME49_005350 fatty acid elongation protein, putative
Length=318
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 46/116 (39%), Positives = 66/116 (56%), Gaps = 8/116 (6%)
Query 23 AEVTWFFYML--KYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIY 80
A W F + KY +LLDT+F+++R R ++FLH YHH++V+ +W V IY
Sbjct 141 ASGLWIFLFIYSKYFELLDTLFIVLRK--RPLNFLHWYHHATVLLYTWDGYCVEQPAGIY 198
Query 81 YVVALNALVHVVMYAYYFMAS-LNSPLARMVKIFVTQLQMAQFLSMTAHACYHVYY 135
+ VA+N VH +MY YYF+A+ L PL IFVT Q++Q C +YY
Sbjct 199 F-VAMNYSVHAIMYFYYFLAAQLQRPLPW--GIFVTIAQISQMFVGMGVTCVSLYY 251
> sce:YJL196C ELO1; Elo1p; K10245 fatty acid elongase 2 [EC:2.3.1.-]
Length=310
Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 42/108 (38%), Positives = 65/108 (60%), Gaps = 6/108 (5%)
Query 30 YMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNALV 89
YM K+V+ DTV M+++ R+++FLH YHH + + + N VGY + V LN V
Sbjct 148 YMTKFVEFADTVLMVLKH--RKLTFLHTYHHGATALLCY-NQLVGYTAVTWVPVTLNLAV 204
Query 90 HVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFLSMTAHACYHVYYYK 137
HV+MY YYF+++ S + K +VT+LQ+ QF+ + Y+V Y K
Sbjct 205 HVLMYWYYFLSA--SGIRVWWKAWVTRLQIVQFM-LDLIVVYYVLYQK 249
> cel:Y53F4B.2 elo-9; fatty acid ELOngation family member (elo-9)
Length=286
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 40/118 (33%), Positives = 64/118 (54%), Gaps = 5/118 (4%)
Query 19 NTRMAEVTW--FFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYD 76
N R W F + K + DT+F+++R R V FLH YHH+ V+ +SW +A++
Sbjct 122 NPRSPSAFWACMFALSKIAEFGDTMFLVLRK--RPVIFLHWYHHAVVLILSW-HAAIELT 178
Query 77 GEIYYVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFLSMTAHACYHVY 134
+ + +N LVH +MY YY + S+ L ++V + VT LQ Q L + +C +Y
Sbjct 179 APGRWFIFMNYLVHSIMYTYYAITSIGYRLPKIVSMTVTFLQTLQMLIGVSISCIVLY 236
> hsa:83401 ELOVL3, CIG-30, CIG30, MGC21435; elongation of very
long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like
3; K10248 elongation of very long chain fatty acids protein
3
Length=270
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 9/108 (8%)
Query 17 VPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYD 76
+ N+ + +W F + K ++L DT F+I+R R + F+H YHHS+V+ V S GY
Sbjct 108 IDNSTVKFWSWVFLLSKVIELGDTAFIILRK--RPLIFIHWYHHSTVL----VYTSFGYK 161
Query 77 GEIY---YVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQ 121
++ + V +N VH +MY YY + + N +M+ + +T LQ+ Q
Sbjct 162 NKVPAGGWFVTMNFGVHAIMYTYYTLKAANVKPPKMLPMLITSLQILQ 209
> ath:AT3G06460 GNS1/SUR4 membrane family protein
Length=298
Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 34/96 (35%), Positives = 56/96 (58%), Gaps = 7/96 (7%)
Query 29 FYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYIS--WVNASVGYDGEIYYVVALN 86
FY+ K ++ +DT+ +I+ + +++SFLHVYHH++V+ + W+ + LN
Sbjct 124 FYLSKILEFVDTLLIILNKSIQRLSFLHVYHHATVVILCYLWLRTR---QSMFPVGLVLN 180
Query 87 ALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQF 122
+ VHV+MY YYF+ ++ S K VT QM QF
Sbjct 181 STVHVIMYGYYFLCAIGS--RPKWKKLVTNFQMVQF 214
> cel:D2024.3 elo-3; fatty acid ELOngation family member (elo-3)
Length=320
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 43/124 (34%), Positives = 72/124 (58%), Gaps = 11/124 (8%)
Query 3 WRAEEYSFMCNRFNVPNTRMAE-VTWF----FYMLKYVDLLDTVFMIVRGNWRQVSFLHV 57
W AE SF ++++ ++ A+ VT F F M K +L+DT+F+++R R + FLH
Sbjct 97 WSAEGNSF---KYSICHSSYAQGVTGFWTEQFAMSKLFELIDTIFIVLRK--RPLIFLHW 151
Query 58 YHHSSVIYISWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQL 117
YHH +V+ +W +A + + + +N VH +MY+YY + SL L + + + VT L
Sbjct 152 YHHVTVMIYTW-HAYKDHTASGRWFIWMNYGVHALMYSYYALRSLKFRLPKQMAMVVTTL 210
Query 118 QMAQ 121
Q+AQ
Sbjct 211 QLAQ 214
> sce:YLR372W SUR4, APA1, ELO3, SRE1, VBM1; Elongase, involved
in fatty acid and sphingolipid biosynthesis; synthesizes very
long chain 20-26-carbon fatty acids from C18-CoA primers;
involved in regulation of sphingolipid biosynthesis; K10246
fatty acid elongase 3 [EC:2.3.1.-]
Length=345
Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 35/94 (37%), Positives = 58/94 (61%), Gaps = 5/94 (5%)
Query 30 YMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNALV 89
Y+ K+V+L+DTVF+++R +++ FLH YHH + + + +G + V+ LN V
Sbjct 161 YLTKFVELIDTVFLVLRR--KKLLFLHTYHHGATALLCYTQL-IGRTSVEWVVILLNLGV 217
Query 90 HVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
HV+MY YYF++S + K +VT+ Q+ QFL
Sbjct 218 HVIMYWYYFLSSCG--IRVWWKQWVTRFQIIQFL 249
> pfa:PFA_0455c fatty acid elongation protein, GNS1/SUR4 family,
putative
Length=322
Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/115 (36%), Positives = 69/115 (60%), Gaps = 13/115 (11%)
Query 28 FFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEI---YYVVA 84
FF + KY +L+DT+F+I++ ++++FLH +HHS+V+ +W Y EI + +
Sbjct 150 FFIISKYFELIDTLFLILKK--KEITFLHWFHHSTVLLYTWDT----YYEEIPVGFIFIC 203
Query 85 LNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQ-FLS--MTAHACYHVYYY 136
+NA VH +MY YYF+AS + + I VT +Q+ Q FL +T++ Y Y Y
Sbjct 204 INAFVHSIMYFYYFLASCYNKKFKW-SIIVTLIQICQMFLGVLLTSYCLYISYIY 257
> cel:F56H11.4 elo-1; fatty acid ELOngation family member (elo-1)
Length=288
Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/127 (29%), Positives = 65/127 (51%), Gaps = 6/127 (4%)
Query 12 CNRFNVPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNA 71
C F+ W F K +L+DT+F+++R R + FLH YHH + +W +
Sbjct 113 CKVFDFTKGENGYWVWLFMASKLFELVDTIFLVLRK--RPLMFLHWYHHILTMIYAWYSH 170
Query 72 SVGYDGEIYYVVALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL---SMTAH 128
+ G Y + LN +VH MY+YYF+ S+ + + +T LQ+ QF+ ++ AH
Sbjct 171 PLT-PGFNRYGIYLNFVVHAFMYSYYFLRSMKIRVPGFIAQAITSLQIVQFIISCAVLAH 229
Query 129 ACYHVYY 135
Y +++
Sbjct 230 LGYLMHF 236
> ath:AT3G06470 GNS1/SUR4 membrane family protein
Length=278
Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 36/110 (32%), Positives = 62/110 (56%), Gaps = 11/110 (10%)
Query 18 PNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYIS--WVNASVGY 75
PN + FY+ K ++ DT+ +I+ + +++SFLHVYHH++V+ + W+
Sbjct 116 PNGPLFFWAQVFYLSKILEFGDTILIILGKSIQRLSFLHVYHHATVVVMCYLWLRTR--- 172
Query 76 DGEIYYVVAL--NALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
+ + +AL N+ VHV+MY YYF+ ++ S K VT Q+ QF+
Sbjct 173 --QSMFPIALVTNSTVHVIMYGYYFLCAVGS--RPKWKRLVTDCQIVQFV 218
> cpv:cgd8_4630 7 pass integral membrane proteinwith FLHWFHH motif
shared with fatty-acyl elongase
Length=323
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query 9 SFMCNRFNVPNTRMAEVTWF--FYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYI 66
S +C+ P T+ W F KY++L+DT F+I R + +SFLH +HH +V+
Sbjct 127 SSICSPPIAPLTKGPAGLWLSLFIYSKYIELIDTFFIIARK--KSLSFLHWFHHLTVLLY 184
Query 67 SWVNASVGYDGEIYYVVALNALVHVVMYAYYFMASLNS-PLARMVKIFVTQLQMAQFLSM 125
+W +A V + A+N VH +MY YY+++S P M+ +T LQ+ Q +
Sbjct 185 TW-DAYVCCQTIGVFFCAINYFVHSIMYFYYYLSSCGKRPKWGMI---ITILQIVQMIIG 240
Query 126 TAHACYHVYY 135
T +YY
Sbjct 241 TILTTSGMYY 250
> cel:F11E6.5 elo-2; fatty acid ELOngation family member (elo-2)
Length=274
Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 9/100 (9%)
Query 27 WFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYV---V 83
W F M K +L DT+F+++R + V F+H YHH+ +++V A V Y + +
Sbjct 118 WAFVMSKAPELGDTMFLVLRK--KPVIFMHWYHHA----LTFVYAVVTYSEHQAWARWSL 171
Query 84 ALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
ALN VH VMY Y+ + +LN R V F+T +Q+ QF+
Sbjct 172 ALNLAVHTVMYFYFAVRALNIQTPRPVAKFITTIQIVQFV 211
> sce:YCR034W FEN1, ELO2, GNS1, VBM2; Fatty acid elongase, involved
in sphingolipid biosynthesis; acts on fatty acids of up
to 24 carbons in length; mutations have regulatory effects
on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory
pathway; K10245 fatty acid elongase 2 [EC:2.3.1.-]
Length=347
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/98 (31%), Positives = 60/98 (61%), Gaps = 13/98 (13%)
Query 30 YMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNALV 89
Y++K+++ +DT F++++ ++++FLH YHH + + + +G + ++LN V
Sbjct 154 YIVKFIEFIDTFFLVLKH--KKLTFLHTYHHGATALLCYTQL-MGTTSISWVPISLNLGV 210
Query 90 HVVMYAYYFMASLNSPLARMVKI----FVTQLQMAQFL 123
HVVMY YYF+A AR +++ +VT+ Q+ QF+
Sbjct 211 HVVMYWYYFLA------ARGIRVWWKEWVTRFQIIQFV 242
> dre:317738 elovl6, cb618, lce, zgc:73089; ELOVL family member
6, elongation of long chain fatty acids (yeast); K10203 elongation
of very long chain fatty acids protein 6 [EC:2.3.1.-]
Length=266
Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 31/93 (33%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Query 29 FYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNAL 88
F + K +L DT+F+++R +++ FLH YHH +V+ SW + G +++ +N L
Sbjct 114 FVLSKAPELGDTLFIVLRK--QKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMT-MNYL 170
Query 89 VHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQ 121
VH VMY+YY + + ++R +F+T Q+ Q
Sbjct 171 VHAVMYSYYALRAAGFKISRKFAMFITLTQITQ 203
> cel:F41H10.7 elo-5; fatty acid ELOngation family member (elo-5)
Length=286
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
Query 33 KYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWV---NASVGYDGEIYYVVALNALV 89
K +LLDTVF+++R R + F+H YHH+ Y + V +V + +VV +N ++
Sbjct 126 KIPELLDTVFIVLRK--RPLIFMHWYHHALTGYYALVCYHEDAV----HMVWVVWMNYII 179
Query 90 HVVMYAYYFMASLNSPLARMVKIFVTQLQMAQF 122
H MY YY + SL P+ V +T QM QF
Sbjct 180 HAFMYGYYLLKSLKVPIPPSVAQAITTSQMVQF 212
> hsa:79071 ELOVL6, FACE, FAE, FLJ23378, LCE, MGC5487; ELOVL family
member 6, elongation of long chain fatty acids (FEN1/Elo2,
SUR4/Elo3-like, yeast); K10203 elongation of very long
chain fatty acids protein 6 [EC:2.3.1.-]
Length=265
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query 29 FYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNAL 88
F + K +L DT+F+I+R +++ FLH YHH +V+ SW + G +++ +N
Sbjct 116 FVLSKAPELGDTIFIILRK--QKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMT-MNYG 172
Query 89 VHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
VH VMY+YY + + ++R +F+T Q+ Q L
Sbjct 173 VHAVMYSYYALRAAGFRVSRKFAMFITLSQITQML 207
> mmu:12686 Elovl3, CIN-2, Cig30; elongation of very long chain
fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3; K10248 elongation
of very long chain fatty acids protein 3
Length=271
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 9/99 (9%)
Query 26 TWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIY---YV 82
++ F + K V+L DT F+I+R R + F+H YHHS+V+ + S GY ++ +
Sbjct 118 SFLFLLSKVVELGDTAFIILRK--RPLIFVHWYHHSTVLLFT----SFGYKNKVPSGGWF 171
Query 83 VALNALVHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQ 121
+ +N VH VMY YY M + ++ + +T LQ+ Q
Sbjct 172 MTMNFGVHSVMYTYYTMKAAKLKHPNLLPMVITSLQILQ 210
> mmu:170439 Elovl6, C77826, FAE, LCE, MGC107467; ELOVL family
member 6, elongation of long chain fatty acids (yeast); K10203
elongation of very long chain fatty acids protein 6 [EC:2.3.1.-]
Length=267
Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 32/95 (33%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query 29 FYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISWVNASVGYDGEIYYVVALNAL 88
F + K +L DT+F+I+R +++ FLH YHH +V+ SW + G +++ +N
Sbjct 116 FVLSKAPELGDTIFIILRK--QKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMT-MNYG 172
Query 89 VHVVMYAYYFMASLNSPLARMVKIFVTQLQMAQFL 123
VH VMY+YY + + ++R +F+T Q+ Q L
Sbjct 173 VHAVMYSYYALRAAGFRVSRKFAMFITLSQITQML 207
> tgo:TGME49_053880 GNS1/SUR4 family domain-containing protein
Length=727
Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats.
Identities = 39/122 (31%), Positives = 58/122 (47%), Gaps = 20/122 (16%)
Query 17 VPNTRMAEVTWFFYMLKYVDLLDTVFMIVRGNWRQVSFLHVYHHSSVIYISW----VNAS 72
VP R V FF + K ++ DTV + +R + + FLHVYHH +V W V S
Sbjct 96 VPPVR--AVICFFTLTKAIEFGDTVILCLRK--KPLIFLHVYHHLTVTLYCWHAQLVTVS 151
Query 73 VGYDGEIYYVVALNALVHVVMYAYYFMASLNS--PLARMVKIFVTQLQMAQ-----FLSM 125
+G++ +N +H VMY YY + L + P+ + ++T Q Q FLS
Sbjct 152 MGHN-----FAFINLGIHGVMYLYYAFSVLQARHPILLACRPYITLSQTVQMFVGLFLSY 206
Query 126 TA 127
A
Sbjct 207 EA 208
Lambda K H
0.332 0.138 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2618291680
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40