bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0393_orf1
Length=183
Score E
Sequences producing significant alignments: (Bits) Value
dre:100149388 itpr1; inositol 1,4,5-triphosphate receptor, typ... 199 3e-51
mmu:16438 Itpr1, D6Pas2, IP3R1, InsP3R, Ip3r, Itpr-1, P400, Pc... 199 3e-51
hsa:3708 ITPR1, DKFZp313E1334, DKFZp313N1434, INSP3R1, IP3R, I... 199 4e-51
xla:399254 itpr1, ip3r, xip3r; inositol 1,4,5-trisphosphate re... 189 4e-48
mmu:16439 Itpr2, AI649341, InsP3R-2, InsP3R-5, Ip3r2, Itpr5; i... 159 5e-39
hsa:3709 ITPR2, IP3R2; inositol 1,4,5-triphosphate receptor, t... 158 1e-38
mmu:16440 Itpr3, Ip3r3, Itpr-3; inositol 1,4,5-triphosphate re... 157 1e-38
hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosp... 157 2e-38
dre:567611 itpr1a; inositol 1,4,5-triphosphate receptor, type ... 147 2e-35
dre:562585 itpr2, si:dkey-196d8.1; inositol 1,4,5-triphosphate... 129 7e-30
cel:F33D4.2 itr-1; Inositol Triphosphate Receptor family membe... 118 1e-26
cpv:cgd8_4630 7 pass integral membrane proteinwith FLHWFHH mot... 30.8 2.7
> dre:100149388 itpr1; inositol 1,4,5-triphosphate receptor, type
1; K04958 inositol 1,4,5-triphosphate receptor type 1
Length=2691
Score = 199 bits (507), Expect = 3e-51, Method: Composition-based stats.
Identities = 93/183 (50%), Positives = 125/183 (68%), Gaps = 3/183 (1%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSK+ DFF R+EDLF EMNWQK+LR QP+LYW SR+MS W+S SF LA ++NL+VAFFY
Sbjct 2177 QGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFY 2236
Query 61 PFPAKAVE---IDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPT 117
P V ++ +SA +WA + +SLA V P G R LI S ++RLI+S+ ++PT
Sbjct 2237 PLEGGGVRGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPT 2296
Query 118 LWLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCY 177
L+LLG V K I L+S +GN GTF + +++D EFLYH+ YL C +G+ H F Y
Sbjct 2297 LFLLGAFNVGNKVIFLMSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFY 2356
Query 178 SVL 180
S+L
Sbjct 2357 SLL 2359
> mmu:16438 Itpr1, D6Pas2, IP3R1, InsP3R, Ip3r, Itpr-1, P400,
Pcp-1, Pcp1, opt; inositol 1,4,5-trisphosphate receptor 1; K04958
inositol 1,4,5-triphosphate receptor type 1
Length=2749
Score = 199 bits (507), Expect = 3e-51, Method: Composition-based stats.
Identities = 93/181 (51%), Positives = 124/181 (68%), Gaps = 1/181 (0%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSK+ DFF R+EDLF EMNWQK+LR QP+LYW +R+MS W+S SF LA ++NL+VAFFY
Sbjct 2235 QGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFY 2294
Query 61 PFPA-KAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTLW 119
PF + ++ S +W + +SLA V A P G R LI S ++RLI+S+ +QPTL+
Sbjct 2295 PFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLF 2354
Query 120 LLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYSV 179
LLG V K I L+S +GN GTF + +++D EFLYH+ YL C +GL H F YS+
Sbjct 2355 LLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSL 2414
Query 180 L 180
L
Sbjct 2415 L 2415
> hsa:3708 ITPR1, DKFZp313E1334, DKFZp313N1434, INSP3R1, IP3R,
IP3R1, SCA15, SCA16; inositol 1,4,5-triphosphate receptor,
type 1; K04958 inositol 1,4,5-triphosphate receptor type 1
Length=2710
Score = 199 bits (506), Expect = 4e-51, Method: Composition-based stats.
Identities = 93/181 (51%), Positives = 124/181 (68%), Gaps = 1/181 (0%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSK+ DFF R+EDLF EMNWQK+LR QP+LYW +R+MS W+S SF LA ++NL+VAFFY
Sbjct 2196 QGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFY 2255
Query 61 PFPA-KAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTLW 119
PF + ++ S +W + +SLA V A P G R LI S ++RLI+S+ +QPTL+
Sbjct 2256 PFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLF 2315
Query 120 LLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYSV 179
LLG V K I L+S +GN GTF + +++D EFLYH+ YL C +GL H F YS+
Sbjct 2316 LLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSL 2375
Query 180 L 180
L
Sbjct 2376 L 2376
> xla:399254 itpr1, ip3r, xip3r; inositol 1,4,5-trisphosphate
receptor, type 1; K04958 inositol 1,4,5-triphosphate receptor
type 1
Length=2693
Score = 189 bits (480), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 93/181 (51%), Positives = 123/181 (67%), Gaps = 1/181 (0%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSK+ DFF+R+EDLF EMNWQK+LR Q +LYW SR+M+ W+S SF LA ++NL+VAFFY
Sbjct 2182 QGSKIHDFFQRSEDLFNEMNWQKKLRAQQVLYWCSRNMTFWSSISFNLAVLMNLLVAFFY 2241
Query 61 PF-PAKAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTLW 119
PF +D R+S +W + +SLA V P G R LI S ++RLI+SI +QPTL+
Sbjct 2242 PFVNVHGGTLDSRLSGLLWTAMLVSLAIVIVLPKPHGIRALIASTILRLIFSIGLQPTLF 2301
Query 120 LLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYSV 179
LLG V K I L S +GN GTF + +++D EFLYH+ YL C +G+ H F YS+
Sbjct 2302 LLGAFNVCNKIIFLTSFVGNRGTFTRGYGAMVLDVEFLYHLLYLLICAMGVFVHEFFYSL 2361
Query 180 L 180
L
Sbjct 2362 L 2362
> mmu:16439 Itpr2, AI649341, InsP3R-2, InsP3R-5, Ip3r2, Itpr5;
inositol 1,4,5-triphosphate receptor 2; K04959 inositol 1,4,5-triphosphate
receptor type 2
Length=2668
Score = 159 bits (402), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 80/182 (43%), Positives = 112/182 (61%), Gaps = 2/182 (1%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV DFF++TEDL+ EM WQK++R P L+W SRH+SLW S SF LA +NL VA FY
Sbjct 2156 QGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFY 2215
Query 61 PFPAKAVE--IDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTL 118
PF E + S +W + + + +F F +G R + S ++R IY+I + PTL
Sbjct 2216 PFGDDGDEGTLSPMFSVLLWVAVAICTSMLFFFSKPVGIRPFLVSVMLRSIYTIGLGPTL 2275
Query 119 WLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYS 178
LLG + K + L+S +GN GTF + +++D FLYH+ Y+ C++GL H F YS
Sbjct 2276 ILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYS 2335
Query 179 VL 180
L
Sbjct 2336 FL 2337
> hsa:3709 ITPR2, IP3R2; inositol 1,4,5-triphosphate receptor,
type 2; K04959 inositol 1,4,5-triphosphate receptor type 2
Length=2701
Score = 158 bits (399), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 80/182 (43%), Positives = 112/182 (61%), Gaps = 2/182 (1%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV DFF++TEDL+ EM WQK++R P L+W SRH+SLW S SF LA +NL VA FY
Sbjct 2189 QGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFY 2248
Query 61 PFPAKAVE--IDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTL 118
PF E + S +W + + + +F F +G R + S ++R IY+I + PTL
Sbjct 2249 PFGDDGDEGTLSPLFSVLLWIAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTL 2308
Query 119 WLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYS 178
LLG + K + L+S +GN GTF + +++D FLYH+ Y+ C++GL H F YS
Sbjct 2309 ILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYS 2368
Query 179 VL 180
L
Sbjct 2369 FL 2370
> mmu:16440 Itpr3, Ip3r3, Itpr-3; inositol 1,4,5-triphosphate
receptor 3; K04960 inositol 1,4,5-triphosphate receptor type
3
Length=2670
Score = 157 bits (398), Expect = 1e-38, Method: Composition-based stats.
Identities = 78/183 (42%), Positives = 112/183 (61%), Gaps = 5/183 (2%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV DFF+++ L EM WQ+RLR PL+YW SR M+LW S SF LA +N+I+AFFY
Sbjct 2163 QGSKVSDFFDQSSFLHNEMEWQRRLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFY 2222
Query 61 PF---PAKAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPT 117
P+ + V IS W ++ S+AA+F + R LI + ++R IY + I PT
Sbjct 2223 PYVEGASTGVLGSPLISLLFWILICFSIAALFT--KRYSVRPLIVALILRSIYYLGIGPT 2280
Query 118 LWLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCY 177
L +LG + K + ++S +GN GTF + +++D EFLYH+ Y+ V+GL H Y
Sbjct 2281 LNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFY 2340
Query 178 SVL 180
S+L
Sbjct 2341 SIL 2343
> hsa:3710 ITPR3, FLJ36205, IP3R, IP3R3; inositol 1,4,5-triphosphate
receptor, type 3; K04960 inositol 1,4,5-triphosphate
receptor type 3
Length=2671
Score = 157 bits (396), Expect = 2e-38, Method: Composition-based stats.
Identities = 77/183 (42%), Positives = 112/183 (61%), Gaps = 5/183 (2%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV DFF+++ L EM WQ++LR PL+YW SR M+LW S SF LA +N+I+AFFY
Sbjct 2164 QGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFY 2223
Query 61 PF---PAKAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPT 117
P+ + V IS W ++ S+AA+F + R LI + ++R IY + I PT
Sbjct 2224 PYMEGASTGVLDSPLISLLFWILICFSIAALFT--KRYSIRPLIVALILRSIYYLGIGPT 2281
Query 118 LWLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCY 177
L +LG + K + ++S +GN GTF + +++D EFLYH+ Y+ V+GL H Y
Sbjct 2282 LNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFY 2341
Query 178 SVL 180
S+L
Sbjct 2342 SIL 2344
> dre:567611 itpr1a; inositol 1,4,5-triphosphate receptor, type
1a; K04958 inositol 1,4,5-triphosphate receptor type 1
Length=2654
Score = 147 bits (372), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 80/181 (44%), Positives = 116/181 (64%), Gaps = 1/181 (0%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSK+ DFF +DLF EM WQK+LR QP+LYW SR+MS W++ SF LA ++NL+VAFFY
Sbjct 2182 QGSKINDFFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFY 2241
Query 61 PFPA-KAVEIDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTLW 119
P +++ +S +W L SL V P RVL+ S +++L +S+ +Q L
Sbjct 2242 PLDGVSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLT 2301
Query 120 LLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYSV 179
LLG V K + ++S +GN G+F + +++DREFL+H+ YL C++GL H F YS+
Sbjct 2302 LLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSL 2361
Query 180 L 180
L
Sbjct 2362 L 2362
> dre:562585 itpr2, si:dkey-196d8.1; inositol 1,4,5-triphosphate
receptor, type 2; K04959 inositol 1,4,5-triphosphate receptor
type 2
Length=2588
Score = 129 bits (323), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 73/182 (40%), Positives = 113/182 (62%), Gaps = 2/182 (1%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV DFF++ +DL+ EM WQK++R L+WVS+H+SLW S SF +A ++NL VA FY
Sbjct 2168 QGSKVNDFFQQFDDLYNEMRWQKKIRNNAPLFWVSKHISLWGSISFNMAVLINLAVALFY 2227
Query 61 PFPAKAVE--IDGRISAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVRLIYSIDIQPTL 118
PF E + +S +W + +S +F P + G + + + R IY++ + PTL
Sbjct 2228 PFGDDGDEGVLPPFLSVLLWGAVVVSTFTLFILPPRGGILAFLVTVIFRSIYTLGLGPTL 2287
Query 119 WLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPFCYS 178
LLG ++ K + L+S +GN GTF + +++D FL H++Y+ C++GL H F YS
Sbjct 2288 LLLGAANLLNKIVFLVSFVGNQGTFTRGYKAVIMDVFFLLHVSYVIVCMLGLFVHEFFYS 2347
Query 179 VL 180
+L
Sbjct 2348 IL 2349
> cel:F33D4.2 itr-1; Inositol Triphosphate Receptor family member
(itr-1); K02522 inositol 1,4,5-triphosphate receptor, invertebrate
Length=2892
Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats.
Identities = 62/185 (33%), Positives = 102/185 (55%), Gaps = 5/185 (2%)
Query 1 QGSKVLDFFERTEDLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFY 60
QGSKV +FF+ E ++ EM WQ++L+++ L W + + LW SF+ AF+VN +VA +Y
Sbjct 2407 QGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYY 2466
Query 61 PFPAKAVEIDGRISAAIWAILFMS-LAAVFAFPGKLGFR----VLIGSALVRLIYSIDIQ 115
P P + + W +F S L A + K+ +++ S L+ SI +
Sbjct 2467 PLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHDKIYLHKTSLLILASLCFLLLSSIGVT 2526
Query 116 PTLWLLGTTQVVIKAIHLISIMGNHGTFNKSISRILIDREFLYHINYLFFCVIGLCCHPF 175
TL++ G Q+V K +H+++ + N G ++ I+ IL R Y + YLF C++GL HP
Sbjct 2527 LTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLLVYLFICILGLLVHPM 2586
Query 176 CYSVL 180
Y +L
Sbjct 2587 IYCIL 2591
> cpv:cgd8_4630 7 pass integral membrane proteinwith FLHWFHH motif
shared with fatty-acyl elongase
Length=323
Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 0/94 (0%)
Query 14 DLFGEMNWQKRLREQPLLYWVSRHMSLWNSFSFYLAFVVNLIVAFFYPFPAKAVEIDGRI 73
D+ E+ W K L W + LW + ++YLA + +I AFF F K +E
Sbjct 29 DILKEIPWFKYLTLPIERNWNGMKLFLWTNDNYYLAHTICIIYAFFIYFGPKIMEKRKPF 88
Query 74 SAAIWAILFMSLAAVFAFPGKLGFRVLIGSALVR 107
+ A+F+F G L + + L++
Sbjct 89 KLEKPLKYWNLFLALFSFIGTLRLMPYVLTNLIK 122
Lambda K H
0.333 0.145 0.472
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4976880524
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40