bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_0969_orf3
Length=201
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_095760 calcium-dependent protein kinase, putative (... 101 2e-21
mmu:77976 Nuak1, AU014801, AW494241, B230104P22Rik, MGC90816, ... 87.4 3e-17
tgo:TGME49_006590 calcium-dependent protein kinase, putative (... 86.3 7e-17
hsa:9891 NUAK1, ARK5, KIAA0537; NUAK family, SNF1-like kinase,... 85.9 9e-17
bbo:BBOV_II007640 18.m06635; calcium-dependent protein kinase 84.3 3e-16
bbo:BBOV_III005470 17.m07489; protein kinase domain containing... 81.3 2e-15
tpv:TP02_0697 calmodulin-domain protein kinase 78.2 2e-14
dre:100330808 MAP/microtubule affinity-regulating kinase 3-like 77.8 2e-14
dre:561496 AMPK-related protein kinase 5-like; K08800 NUAK fam... 77.8 2e-14
dre:767634 MGC153725; zgc:153725 (EC:2.7.11.1); K08798 MAP/mic... 77.8 3e-14
hsa:81788 NUAK2, DKFZp434J037, DKFZp686F01113, FLJ90349, SNARK... 76.6 6e-14
xla:495312 hypothetical LOC495312; K08798 MAP/microtubule affi... 76.3 7e-14
hsa:4140 MARK3, CTAK1, KP78, PAR1A; MAP/microtubule affinity-r... 76.3 8e-14
dre:571279 MAP/microtubule affinity-regulating kinase 3-like; ... 75.9 8e-14
cel:F58H12.1 kin-29; protein KINase family member (kin-29) 75.9 8e-14
dre:561563 si:dkey-261e22.1; K08800 NUAK family, SNF1-like kin... 75.5 1e-13
mmu:232944 Mark4, 2410090P21Rik, C79806, Markl1; MAP/microtubu... 75.5 1e-13
hsa:57787 MARK4, FLJ12177, FLJ90097, KIAA1860, MARK4L, MARK4S,... 75.5 1e-13
xla:399395 mark3, Par-1A, par-1, par1; MAP/microtubule affinit... 75.5 1e-13
cel:H39E23.1 par-1; abnormal embryonic PARtitioning of cytopla... 75.5 1e-13
ath:AT1G29230 CIPK18; CIPK18 (CBL-INTERACTING PROTEIN KINASE 1... 75.1 1e-13
dre:100003170 mark1; MAP/microtubule affinity-regulating kinas... 75.1 1e-13
mmu:17169 Mark3, 1600015G02Rik, A430080F22Rik, C-TAK1, ETK-1, ... 75.1 2e-13
dre:564235 im:7152987; si:dkey-189i22.2; K08797 hormonally upr... 74.7 2e-13
ath:AT5G21326 protein kinase family protein / NAF domain-conta... 74.7 2e-13
ath:AT1G01140 CIPK9; CIPK9 (CBL-INTERACTING PROTEIN KINASE 9);... 74.7 2e-13
dre:569346 MAP/microtubule affinity-regulating kinase 3-like 74.3 3e-13
mmu:226778 Mark1, AW491150, B930025N23Rik, Emk3, KIAA1477, mKI... 73.9 3e-13
ath:AT2G30360 SIP4; SIP4 (SOS3-INTERACTING PROTEIN 4); kinase/... 73.9 3e-13
xla:432201 mark1, MGC80341; MAP/microtubule affinity-regulatin... 73.6 4e-13
tgo:TGME49_025490 calcium-dependent protein kinase, putative (... 73.6 4e-13
hsa:4139 MARK1, KIAA1477, MARK, MGC126512, MGC126513; MAP/micr... 73.6 5e-13
dre:560275 nuak2, si:rp71-11b17.3; NUAK family, SNF1-like kina... 73.2 5e-13
tgo:TGME49_017600 calcium-dependent protein kinase, putative (... 73.2 6e-13
mmu:74137 Nuak2, 1200013B22Rik, Omphk2, Snark, mKIAA0537; NUAK... 72.8 7e-13
cpv:cgd2_1060 calcium/calmodulin dependent protein kinase with... 72.8 8e-13
xla:397927 melk, xmelk; maternal embryonic leucine zipper kina... 72.4 9e-13
cpv:cgd3_260 hypothetical protein 72.0 1e-12
ath:AT2G34180 CIPK13; CIPK13 (CBL-INTERACTING PROTEIN KINASE 1... 72.0 1e-12
cpv:cgd7_1840 calcium/calmodulin-dependent protein kinase with... 72.0 1e-12
dre:334300 mark3, MGC152848, fi39g08, wu:fi39g08, zgc:152848, ... 72.0 1e-12
tpv:TP02_0399 calcium-dependent protein kinase; K13412 calcium... 72.0 1e-12
mmu:235344 Sik2, G630080D20Rik, Snf1lk2; salt inducible kinase... 71.6 2e-12
ath:AT5G01810 CIPK15; CIPK15 (CBL-INTERACTING PROTEIN KINASE 1... 71.2 2e-12
cpv:cgd2_1300 calcium/calmodulin dependent protein kinase with... 71.2 2e-12
ath:AT5G45810 CIPK19; CIPK19 (CBL-INTERACTING PROTEIN KINASE 1... 71.2 2e-12
cel:K07A9.2 cmk-1; CaM Kinase family member (cmk-1); K08794 ca... 71.2 2e-12
tgo:TGME49_042400 calcium-dependent protein kinase, putative (... 70.9 3e-12
ath:AT1G30270 CIPK23; CIPK23 (CBL-INTERACTING PROTEIN KINASE 2... 70.9 3e-12
tpv:TP01_0983 calcium-dependent protein kinase; K13412 calcium... 70.9 3e-12
> tgo:TGME49_095760 calcium-dependent protein kinase, putative
(EC:2.7.11.17)
Length=534
Score = 101 bits (251), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 49/128 (38%), Positives = 74/128 (57%), Gaps = 7/128 (5%)
Query 80 LKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWT 139
++ E+ V + +DHP IARL+E++ED++ + LV EYCPGG L+ L + PE+ AR
Sbjct 112 IRNEVNVRVRVDHPNIARLIEIYEDEKQLALVLEYCPGGDLFSHLCDRGRFPEQTARVIV 171
Query 140 LQMVRAVGFLQGCGVVHRNLRLESWQLTKQG-------CFPPLKLYGLSHSTRWHKREGR 192
QM+ + +L VVHR+LRLE W L Q P+KL L ++T W + +
Sbjct 172 QQMLAVLCYLHAHDVVHRDLRLEKWVLATQHDGSGFRFLAGPVKLVDLGNATVWSNKSKK 231
Query 193 LNAACGLL 200
++ CG L
Sbjct 232 MDVTCGAL 239
> mmu:77976 Nuak1, AU014801, AW494241, B230104P22Rik, MGC90816,
Omphk1; NUAK family, SNF1-like kinase, 1 (EC:2.7.11.1); K08800
NUAK family, SNF1-like kinase [EC:2.7.11.1]
Length=658
Score = 87.4 bits (215), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 52/152 (34%), Positives = 86/152 (56%), Gaps = 5/152 (3%)
Query 48 GKVCRVTCKRSGRKAEALVVRK-HLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
GKV R T + SGR +RK ++D L + +++EIE+ SL+HP+I + EVFE+
Sbjct 68 GKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVFENKD 127
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+ ++ EY G LYD+++ ++ E R + Q+V AV + GVVHR+L+LE+ L
Sbjct 128 KIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI-L 186
Query 167 TKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
C + +GLS+ ++++ L CG
Sbjct 187 LDDNCNIKIADFGLSN---LYQKDKFLQTFCG 215
> tgo:TGME49_006590 calcium-dependent protein kinase, putative
(EC:2.7.11.17 3.4.22.53); K13412 calcium-dependent protein
kinase [EC:2.7.11.1]
Length=761
Score = 86.3 bits (212), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 4/157 (2%)
Query 35 YSFDFCVLRREDAGKVCRVTCKRSGR-KAEALVVRKHLEDPLQLETLKKEIEVWLSLDHP 93
Y D L + G V + K +G+ +A + + +++ LE ++EI + LDHP
Sbjct 224 YEIDTATLGQGTYGSVSKARKKDTGQMRAVKTISKSQVKN---LERFRQEIAIMKELDHP 280
Query 94 YIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCG 153
+ +L E FED R +YLV E C GG L+D + S + E+ A QM AV +L
Sbjct 281 NVIKLFETFEDHRNIYLVMELCTGGELFDRIISEGRLTEKQAAVLMKQMFSAVHYLHSNN 340
Query 154 VVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKRE 190
++HR+L+ E++ PLK+ S R+ K E
Sbjct 341 IMHRDLKPENFLFLDSARDSPLKIIDFGLSCRFKKGE 377
> hsa:9891 NUAK1, ARK5, KIAA0537; NUAK family, SNF1-like kinase,
1 (EC:2.7.11.1); K08800 NUAK family, SNF1-like kinase [EC:2.7.11.1]
Length=661
Score = 85.9 bits (211), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 51/152 (33%), Positives = 85/152 (55%), Gaps = 5/152 (3%)
Query 48 GKVCRVTCKRSGRKAEALVVRK-HLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
GKV R T + SGR +RK ++D + +++EIE+ SL+HP+I + EVFE+
Sbjct 67 GKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKD 126
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+ ++ EY G LYD+++ ++ E R + Q+V AV + GVVHR+L+LE+ L
Sbjct 127 KIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI-L 185
Query 167 TKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
C + +GLS+ ++++ L CG
Sbjct 186 LDDNCNIKIADFGLSN---LYQKDKFLQTFCG 214
> bbo:BBOV_II007640 18.m06635; calcium-dependent protein kinase
Length=580
Score = 84.3 bits (207), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 46/137 (33%), Positives = 75/137 (54%), Gaps = 2/137 (1%)
Query 47 AGKVCRVTCKRSGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
G V + K+S R ++ + +L + EI ++ LDHP IA L EV+E+
Sbjct 154 GGSVHQAVDKKSHRTFALKTLKTDFKFRKRLISTYNEIAIYTQLDHPNIAFLHEVYEEPG 213
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+ +L+ E+C GG LYD L ++ E A++ T+QM+ A+ +L G+ HR+L+LE+W
Sbjct 214 SCHLLMEHCNGGELYDRLEKYKRFAEGYAKSVTVQMLLAINYLHNNGICHRDLKLENWVF 273
Query 167 TKQGCFPPLKL--YGLS 181
Q LK+ +G S
Sbjct 274 ATQDMGALLKMIDFGFS 290
> bbo:BBOV_III005470 17.m07489; protein kinase domain containing
protein; K13412 calcium-dependent protein kinase [EC:2.7.11.1]
Length=755
Score = 81.3 bits (199), Expect = 2e-15, Method: Composition-based stats.
Identities = 47/159 (29%), Positives = 83/159 (52%), Gaps = 4/159 (2%)
Query 31 IGNAYSFDFCVLRREDAGKVCRVTCKRSGRKAEALVVRKH-LEDPLQLETLKKEIEVWLS 89
I + Y L + G+V + K +G V+RK +E+ +++ K+EI + +
Sbjct 295 ITDVYDLHTNRLGKGSYGQVLKACHKETGEVKAVKVIRKAAIENAMRM---KREITIMKN 351
Query 90 LDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFL 149
LDHP I +LLE++ED+ +YLV E C GG L++ + E+ A T Q+ A+ +
Sbjct 352 LDHPNIVKLLEIYEDEECLYLVMEMCSGGELFEEIVRRGCFSEQYAATMMRQLFSAIAYC 411
Query 150 QGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHK 188
G G++HR+L+ E+ P+K+ +T+ +K
Sbjct 412 HGKGILHRDLKPENILYANTSDNSPIKVIDWGFATKCYK 450
> tpv:TP02_0697 calmodulin-domain protein kinase
Length=579
Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 50/161 (31%), Positives = 83/161 (51%), Gaps = 11/161 (6%)
Query 20 VRYTSRLMRDF-IG-NAYSFDFCVLRREDAGKVCRVTCKRSGRKAEALVVRKHLEDPL-Q 76
+ YT++L + IG NA + C G V KR+ +K AL L + +
Sbjct 126 IIYTNKLTNVYTIGTNAIGYGIC-------GSVNHCVNKRT-QKVYALKSLSTLANSKRK 177
Query 77 LETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVAR 136
+ ++ E+ ++ LDHP IA + E ++D+ ++V EYC G LYD L + ++ E A
Sbjct 178 MTSVFNELSIFTQLDHPNIAFMHEAYDDNTLCHIVMEYCSGNELYDRLDTYKRFSESYAI 237
Query 137 TWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKL 177
T QM+ + +L G+ HR+L+LE+W + Q LK+
Sbjct 238 KMTFQMLLTLNYLHSNGICHRDLKLENWVFSNQEIDSLLKM 278
> dre:100330808 MAP/microtubule affinity-regulating kinase 3-like
Length=527
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 57 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 116
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E D+ +YLV EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 117 IVKLFEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHI 176
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 177 VHRDLKAENLLL 188
> dre:561496 AMPK-related protein kinase 5-like; K08800 NUAK family,
SNF1-like kinase [EC:2.7.11.1]
Length=612
Score = 77.8 bits (190), Expect = 2e-14, Method: Composition-based stats.
Identities = 54/158 (34%), Positives = 87/158 (55%), Gaps = 5/158 (3%)
Query 42 LRREDAGKVCRVTCKRSGRKAEALVVRKH-LEDPLQLETLKKEIEVWLSLDHPYIARLLE 100
L R GKV + + SGR+ +RK ++D + +++EIE+ SL HP+I + E
Sbjct 53 LGRGTYGKVRKAIERHSGREVAIKSIRKEKIKDEQDMVHIRREIEIMSSLRHPHIISIYE 112
Query 101 VFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLR 160
VFE+ + +V EY G LYD+++ ++ E R + Q+V AV + GVVHR+L+
Sbjct 113 VFENKDKIVIVMEYASKGELYDYISERRRLTERETRHFFRQIVSAVHYCHKNGVVHRDLK 172
Query 161 LESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
LE+ L + C + +GLS+ +HK + L CG
Sbjct 173 LEN-VLLDENCNIKIADFGLSN--LYHK-DKLLQTFCG 206
> dre:767634 MGC153725; zgc:153725 (EC:2.7.11.1); K08798 MAP/microtubule
affinity-regulating kinase [EC:2.7.11.1]
Length=754
Score = 77.8 bits (190), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E D+ +YLV EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 115 IVKLFEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHI 174
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 175 VHRDLKAENLLL 186
> hsa:81788 NUAK2, DKFZp434J037, DKFZp686F01113, FLJ90349, SNARK;
NUAK family, SNF1-like kinase, 2 (EC:2.7.11.1); K08800 NUAK
family, SNF1-like kinase [EC:2.7.11.1]
Length=628
Score = 76.6 bits (187), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 49/136 (36%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query 48 GKVCRVTCKRSGRKAEALVVRK-HLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
GKV + + SGR +RK ++D L +++EIE+ SL+HP+I + EVFE+
Sbjct 65 GKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSS 123
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+ +V EY G LYD+++ Q+ E AR + Q+V AV + VVHR+L+LE+ L
Sbjct 124 KIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILL 183
Query 167 TKQGCFPPLKLYGLSH 182
G + +GLS+
Sbjct 184 DANGNI-KIADFGLSN 198
> xla:495312 hypothetical LOC495312; K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=729
Score = 76.3 bits (186), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YLV EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 115 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKQI 174
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 175 VHRDLKAENLLL 186
> hsa:4140 MARK3, CTAK1, KP78, PAR1A; MAP/microtubule affinity-regulating
kinase 3 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=753
Score = 76.3 bits (186), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YL+ EY GG ++D+L + + E+ AR+ Q+V AV + +
Sbjct 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRI 174
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 175 VHRDLKAENLLL 186
> dre:571279 MAP/microtubule affinity-regulating kinase 3-like;
K08798 MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Length=755
Score = 75.9 bits (185), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 57 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKGLNHPN 116
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YLV EY GG ++D+L S + E+ AR Q+V AV + +
Sbjct 117 IVQLFEVIETEKTLYLVMEYASGGEVFDYLVSHGRMKEKEARGKFRQIVSAVHYCHLKNI 176
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 177 VHRDLKAENLLL 188
> cel:F58H12.1 kin-29; protein KINase family member (kin-29)
Length=822
Score = 75.9 bits (185), Expect = 8e-14, Method: Composition-based stats.
Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 4/126 (3%)
Query 73 DPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPE 132
D L L++E+++ +DHP+I + E+ D +Y+VSEYC G LY+ L + E
Sbjct 53 DRENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAE 112
Query 133 EVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGR 192
VAR W + AV +L G+VHR+L+ E+ L K + +G S+ + +
Sbjct 113 NVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIID-FGFSN---FQTGDQL 168
Query 193 LNAACG 198
LN CG
Sbjct 169 LNTWCG 174
> dre:561563 si:dkey-261e22.1; K08800 NUAK family, SNF1-like kinase
[EC:2.7.11.1]
Length=617
Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 52/159 (32%), Positives = 83/159 (52%), Gaps = 5/159 (3%)
Query 41 VLRREDAGKVCRVTCKRSGRKAEALVVRKH-LEDPLQLETLKKEIEVWLSLDHPYIARLL 99
L R GKV + + +GR +RK ++D + +++EIE+ SL HP+I +
Sbjct 58 TLGRGTYGKVKKAIERHTGRVVAIKSIRKEKIKDEQDMVHIRREIEIMSSLRHPHIISIY 117
Query 100 EVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNL 159
EVFE+ + +V EY G LYD+++ ++ E R + Q+V AV + GVVHR+L
Sbjct 118 EVFENKDKIVIVMEYASKGELYDYISERRRLTERETRHFFRQIVSAVHYCHKKGVVHRDL 177
Query 160 RLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
+LE+ L G +K+ S +HK + L CG
Sbjct 178 KLENILLDDNGN---IKIADFGLSNLYHK-DKLLQTFCG 212
> mmu:232944 Mark4, 2410090P21Rik, C79806, Markl1; MAP/microtubule
affinity-regulating kinase 4 (EC:2.7.11.1); K08798 MAP/microtubule
affinity-regulating kinase [EC:2.7.11.1]
Length=752
Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +LR G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YLV EY G ++D+L S + E+ AR Q+V AV + +
Sbjct 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 178 VHRDLKAENLLL 189
> hsa:57787 MARK4, FLJ12177, FLJ90097, KIAA1860, MARK4L, MARK4S,
MARKL1, MARKL1L; MAP/microtubule affinity-regulating kinase
4 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=752
Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +LR G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPN 117
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YLV EY G ++D+L S + E+ AR Q+V AV + +
Sbjct 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 178 VHRDLKAENLLL 189
> xla:399395 mark3, Par-1A, par-1, par1; MAP/microtubule affinity-regulating
kinase 3 (EC:2.7.11.1); K08798 MAP/microtubule
affinity-regulating kinase [EC:2.7.11.1]
Length=725
Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YL+ EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHI 174
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 175 VHRDLKAENLLL 186
> cel:H39E23.1 par-1; abnormal embryonic PARtitioning of cytoplasm
family member (par-1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=1192
Score = 75.5 bits (184), Expect = 1e-13, Method: Composition-based stats.
Identities = 36/111 (32%), Positives = 65/111 (58%), Gaps = 0/111 (0%)
Query 58 SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPG 117
+G + ++ K +P L+ L +E+++ LDHP I +L +V E ++ +YLV EY G
Sbjct 192 TGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASG 251
Query 118 GSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTK 168
G ++D+L + + E+ AR Q+V AV +L ++HR+L+ E+ L +
Sbjct 252 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ 302
> ath:AT1G29230 CIPK18; CIPK18 (CBL-INTERACTING PROTEIN KINASE
18); ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=520
Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 41/119 (34%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Query 80 LKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWT 139
+K+EI + + HPYI L EV +Y V EY GG L++ +A + PEE AR +
Sbjct 119 IKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAK-GRLPEETARRYF 177
Query 140 LQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
Q++ +V F G GV HR+L+ E+ L +G + +GLS +++G + CG
Sbjct 178 QQLISSVSFCHGRGVYHRDLKPENLLLDNKGNL-KVSDFGLSAVAEQLRQDGLCHTFCG 235
> dre:100003170 mark1; MAP/microtubule affinity-regulating kinase
1 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=772
Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 59 NYRLLKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKVLNHPN 118
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YL+ EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 119 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 178
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 179 VHRDLKAENLLL 190
> mmu:17169 Mark3, 1600015G02Rik, A430080F22Rik, C-TAK1, ETK-1,
ETK1, Emk2, KIAA4230, MPK10; MAP/microtubule affinity-regulating
kinase 3 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=744
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPN 114
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YL+ EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 175 VHRDLKAENLLL 186
> dre:564235 im:7152987; si:dkey-189i22.2; K08797 hormonally upregulated
Neu-associated kinase [EC:2.7.11.1]
Length=434
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 43/124 (34%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
Query 77 LETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVAR 136
L+ L++E + + HP+IA+LL++ E + YLV E CPGG+L +++ ++ E A
Sbjct 92 LKNLRREGNIQQMIRHPHIAQLLDIMETENRFYLVMELCPGGNLMNYIYENKRLEEREAN 151
Query 137 TWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKL--YGLSHSTRWHKREGRLN 194
+ Q+V AV L GVVHR+L++E+ L LKL +GLS+S +
Sbjct 152 KYVRQLVMAVEHLHRAGVVHRDLKIENLLLDDHDN---LKLIDFGLSNSAGILGYSDPFS 208
Query 195 AACG 198
CG
Sbjct 209 TQCG 212
> ath:AT5G21326 protein kinase family protein / NAF domain-containing
protein
Length=439
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 1/148 (0%)
Query 51 CRVTCKRSGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYL 110
C V + R A ++ ++ + E +++EI ++HP + RL EV +Y+
Sbjct 29 CAVNTETGERVALKILDKEKVLKHKMAEQIRREICTMKLINHPNVVRLYEVLASKTKIYI 88
Query 111 VSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQG 170
V E+ GG L+D + + EE AR + Q++ AV + GV HR+L+ E+ L QG
Sbjct 89 VLEFGTGGELFDKIVHDGRLKEENARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDAQG 148
Query 171 CFPPLKLYGLSHSTRWHKREGRLNAACG 198
+ +GLS +R + +G L+ ACG
Sbjct 149 NL-KVSDFGLSALSRQVRGDGLLHTACG 175
> ath:AT1G01140 CIPK9; CIPK9 (CBL-INTERACTING PROTEIN KINASE 9);
ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=447
Score = 74.7 bits (182), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query 77 LETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVAR 136
+E LK+EI + HP + ++EV +Y+V E GG L+D +A + E+ AR
Sbjct 61 VEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEAR 120
Query 137 TWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAA 196
+ Q++ AV + GV HR+L+ E+ L G + +GLS +R + +G L+ A
Sbjct 121 RYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVL-KVSDFGLSAFSRQVREDGLLHTA 179
Query 197 CG 198
CG
Sbjct 180 CG 181
> dre:569346 MAP/microtubule affinity-regulating kinase 3-like
Length=743
Score = 74.3 bits (181), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +G++ ++ K +P L+ L +E+ + +L HP
Sbjct 57 NYRLLKTIGKGNFAKVKLARHILTGKEVAIKIIDKTQLNPTSLQKLFREVRIMKTLHHPN 116
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YLV EY GG ++D+L S + E AR Q+V AV + +
Sbjct 117 IVQLFEVIETEKTLYLVMEYASGGEVFDYLVSHGRMKEIEARAKFRQIVSAVHYCHQKNI 176
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 177 VHRDLKAENLLL 188
> mmu:226778 Mark1, AW491150, B930025N23Rik, Emk3, KIAA1477, mKIAA1477;
MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1);
K08798 MAP/microtubule affinity-regulating kinase
[EC:2.7.11.1]
Length=795
Score = 73.9 bits (180), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 40/122 (32%), Positives = 67/122 (54%), Gaps = 3/122 (2%)
Query 48 GKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFED 104
G +V R +GR+ ++ K +P L+ L +E+ + L+HP I +L EV E
Sbjct 69 GNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIET 128
Query 105 DRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESW 164
++ +YLV EY GG ++D+L + + E+ AR Q+V AV + +VHR+L+ E+
Sbjct 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENL 188
Query 165 QL 166
L
Sbjct 189 LL 190
> ath:AT2G30360 SIP4; SIP4 (SOS3-INTERACTING PROTEIN 4); kinase/
protein kinase
Length=435
Score = 73.9 bits (180), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 43/156 (27%), Positives = 78/156 (50%), Gaps = 6/156 (3%)
Query 48 GKVCRVTCKRSGRKAEALVVR-----KHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVF 102
G +V R R +++ V+ K L +P +K+EI + L HP I +L EV
Sbjct 30 GAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVKLHEVM 89
Query 103 EDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLE 162
++ E+ GG L++ ++ + E+++R + Q++ AVG+ GV HR+L+ E
Sbjct 90 ATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPE 149
Query 163 SWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
+ + + G + +GLS T + +G L+ CG
Sbjct 150 NLLIDENGNL-KVSDFGLSALTDQIRPDGLLHTLCG 184
> xla:432201 mark1, MGC80341; MAP/microtubule affinity-regulating
kinase 1 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating
kinase [EC:2.7.11.1]
Length=792
Score = 73.6 bits (179), Expect = 4e-13, Method: Composition-based stats.
Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +GR+ ++ K +P L+ L +E+ + L+HP
Sbjct 59 NYRLLKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPN 118
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ +YL+ EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 119 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCI 178
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 179 VHRDLKAENLLL 190
> tgo:TGME49_025490 calcium-dependent protein kinase, putative
(EC:1.6.3.1 2.7.11.17 3.2.1.60); K13412 calcium-dependent protein
kinase [EC:2.7.11.1]
Length=711
Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 44/128 (34%), Positives = 65/128 (50%), Gaps = 3/128 (2%)
Query 59 GRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGG 118
R+A + + ++ED + ++EIE+ SLDHP I RL E FED YLV EYC GG
Sbjct 264 ARRAAKKIPKCYVED---ADRFRQEIEIMKSLDHPNIVRLYETFEDMTDFYLVMEYCTGG 320
Query 119 SLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLY 178
L+D L E +A Q++ AV + V HR+L+ E++ P+KL
Sbjct 321 ELFDRLVHQGVFTEALACRIMRQILAAVAYCHAHRVAHRDLKPENFLFLHDNPESPIKLI 380
Query 179 GLSHSTRW 186
+ R+
Sbjct 381 DFGLAARF 388
> hsa:4139 MARK1, KIAA1477, MARK, MGC126512, MGC126513; MAP/microtubule
affinity-regulating kinase 1 (EC:2.7.11.1); K08798
MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Length=795
Score = 73.6 bits (179), Expect = 5e-13, Method: Composition-based stats.
Identities = 37/109 (33%), Positives = 63/109 (57%), Gaps = 0/109 (0%)
Query 58 SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPG 117
+GR+ ++ K +P L+ L +E+ + L+HP I +L EV E ++ +YLV EY G
Sbjct 82 TGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASG 141
Query 118 GSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
G ++D+L + + E+ AR Q+V AV + +VHR+L+ E+ L
Sbjct 142 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLL 190
> dre:560275 nuak2, si:rp71-11b17.3; NUAK family, SNF1-like kinase,
2; K08800 NUAK family, SNF1-like kinase [EC:2.7.11.1]
Length=576
Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 46/133 (34%), Positives = 71/133 (53%), Gaps = 2/133 (1%)
Query 57 RSGRKAEALVVRKH-LEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYC 115
RSG +RK + D +L +++EIE+ SL HP+I + EVFE+ + +V E
Sbjct 49 RSGTAVAIKSIRKEKIRDEQELTHIRREIEIMSSLSHPHIISIYEVFENKDKIVIVMELA 108
Query 116 PGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPL 175
G L+D++ Q E AR + Q+V AV + G+VHR+L+LE+ L G +
Sbjct 109 SRGDLFDYICDSQPLAETQARHFFRQIVSAVHYCHRNGIVHRDLKLENILLDCNGNI-KI 167
Query 176 KLYGLSHSTRWHK 188
+GLS+ R K
Sbjct 168 ADFGLSNLYRGDK 180
> tgo:TGME49_017600 calcium-dependent protein kinase, putative
(EC:2.7.11.17)
Length=488
Score = 73.2 bits (178), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 9/145 (6%)
Query 48 GKVCRVTCKRSGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRA 107
GKV VT K++G + + ++ P Q E +K EIE+ +L+HP I +L E ++D
Sbjct 195 GKVQLVTNKKTGARRACKSI--GIQSPDQWELIKAEIELLKALNHPNIMKLYETYQDGYT 252
Query 108 VYLVSEYCPGGSLYDFLAS-----LQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLE 162
+YL+ E C GG L+D + EE W Q++ A + GVVHR+L+ E
Sbjct 253 IYLIIELCHGGPLFDRIVQHYEKLRSPITEEQVSHWMRQILSACAYCHERGVVHRDLKPE 312
Query 163 SWQLTKQGCFPPLKL--YGLSHSTR 185
+ P+K+ +GLS + +
Sbjct 313 NILFVDSSPDSPIKVIDFGLSDTMQ 337
> mmu:74137 Nuak2, 1200013B22Rik, Omphk2, Snark, mKIAA0537; NUAK
family, SNF1-like kinase, 2 (EC:2.7.11.1); K08800 NUAK family,
SNF1-like kinase [EC:2.7.11.1]
Length=639
Score = 72.8 bits (177), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 13/150 (8%)
Query 48 GKVCRVTCKRSGRKAEALVVRK-HLEDPLQLETLKKEIEVWLSLDHPYI--------ARL 98
GKV + + SGR +RK ++D L +++EIE+ SL+HP+I +RL
Sbjct 69 GKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRL 127
Query 99 LEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRN 158
+ VFE+ + +V EY G LYD+++ + E AR + Q+V A+ + G+VHR+
Sbjct 128 VTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRD 187
Query 159 LRLESWQLTKQGCFPPLKLYGLSHSTRWHK 188
L+LE+ L G +K+ S +HK
Sbjct 188 LKLENILLDANGN---IKIADFGLSNLYHK 214
> cpv:cgd2_1060 calcium/calmodulin dependent protein kinase with
a kinas domain and 4 calmodulin-like EF hands ; K00908 Ca2+/calmodulin-dependent
protein kinase [EC:2.7.11.17]
Length=718
Score = 72.8 bits (177), Expect = 8e-13, Method: Composition-based stats.
Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 0/122 (0%)
Query 77 LETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVAR 136
L+ KEI + +LDHP I +L E ++D +YLV E C GG L+D + S E A
Sbjct 240 LDNFMKEINILKNLDHPNIVKLYETYQDKENIYLVMELCSGGELFDRIISQGSFDEIYAA 299
Query 137 TWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAA 196
Q++ + + G+VHR+L+ E++ + PLK+ + R + + LN
Sbjct 300 NLMKQVLSTICYCHDHGIVHRDLKPENFLFLNKNYNAPLKIIDFGLAARVNNEDTSLNTR 359
Query 197 CG 198
G
Sbjct 360 AG 361
> xla:397927 melk, xmelk; maternal embryonic leucine zipper kinase
(EC:2.7.11.1); K08799 maternal embryonic leucine zipper
kinase [EC:2.7.11.1]
Length=651
Score = 72.4 bits (176), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 32/87 (36%), Positives = 53/87 (60%), Gaps = 0/87 (0%)
Query 77 LETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVAR 136
L +K EI+ +L H ++ RL V E + +++V EYCPGG L+D++ + + EE AR
Sbjct 53 LPRVKTEIDAMKNLSHQHVCRLYHVIETPKKIFMVLEYCPGGELFDYIIAKDRLTEEEAR 112
Query 137 TWTLQMVRAVGFLQGCGVVHRNLRLES 163
+ Q+V AV ++ G HR+L+ E+
Sbjct 113 VFFRQIVSAVAYIHSQGYAHRDLKPEN 139
> cpv:cgd3_260 hypothetical protein
Length=1180
Score = 72.0 bits (175), Expect = 1e-12, Method: Composition-based stats.
Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 0/85 (0%)
Query 80 LKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWT 139
++E+++ LDHP IA+L E FED ++YL+ E C GG L+D L+ + + E V
Sbjct 100 FRQEMQLLSILDHPNIAKLFESFEDYNSIYLIMELCTGGELFDRLSHVGRFSERVTAHLI 159
Query 140 LQMVRAVGFLQGCGVVHRNLRLESW 164
QM+ A+ + G+VHR+L+ E++
Sbjct 160 KQMLSAISYCHSKGIVHRDLKPENF 184
> ath:AT2G34180 CIPK13; CIPK13 (CBL-INTERACTING PROTEIN KINASE
13); ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=502
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 43/119 (36%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Query 80 LKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWT 139
+K+EI + + HPYI LLEV +Y+V EY GG LY+ +A + E AR +
Sbjct 102 IKREISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVAR-GRLREGTARRYF 160
Query 140 LQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
Q++ +V F GV HR+L+LE+ L +G + +GLS + K+EG CG
Sbjct 161 QQLISSVAFCHSRGVYHRDLKLENLLLDDKGNV-KVSDFGLSVVSEQLKQEGICQTFCG 218
> cpv:cgd7_1840 calcium/calmodulin-dependent protein kinase with
a kinase domain and 4 calmodulin like EF hands ; K13412 calcium-dependent
protein kinase [EC:2.7.11.1]
Length=676
Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query 60 RKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGS 119
R+A + + +ED ++ K+EIE+ SLDHP I RL E FED+ +YLV E C GG
Sbjct 231 RRAAKKIPKYFVED---VDRFKQEIEIMKSLDHPNIIRLYETFEDNTDIYLVMELCTGGE 287
Query 120 LYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYG 179
L++ + + E A ++ AV + V HR+L+ E++ PLKL
Sbjct 288 LFERVVHKRVFRESDAARIMKDVLSAVAYCHKLNVAHRDLKPENFLFLTDSPDSPLKLID 347
Query 180 LSHSTRW 186
+ R+
Sbjct 348 FGLAARF 354
> dre:334300 mark3, MGC152848, fi39g08, wu:fi39g08, zgc:152848,
zgc:55693; MAP/microtubule affinity-regulating kinase 3 (EC:2.7.11.1);
K08798 MAP/microtubule affinity-regulating kinase
[EC:2.7.11.1]
Length=722
Score = 72.0 bits (175), Expect = 1e-12, Method: Composition-based stats.
Identities = 39/132 (29%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query 38 DFCVLRREDAGKVCRVTCKR---SGRKAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPY 94
++ +L+ G +V R +G + ++ K +P L+ L +E+ + +L+HP
Sbjct 56 NYRLLKTIGKGNFAKVKLARHILTGSEVAIKMIDKTQLNPTSLQKLSREVTIMKNLNHPN 115
Query 95 IARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGV 154
I +L EV E ++ ++LV EY GG ++D+L + + E+ AR Q+V AV + +
Sbjct 116 IVKLFEVIETEKTLFLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 175
Query 155 VHRNLRLESWQL 166
VHR+L+ E+ L
Sbjct 176 VHRDLKAENLLL 187
> tpv:TP02_0399 calcium-dependent protein kinase; K13412 calcium-dependent
protein kinase [EC:2.7.11.1]
Length=844
Score = 72.0 bits (175), Expect = 1e-12, Method: Composition-based stats.
Identities = 39/117 (33%), Positives = 67/117 (57%), Gaps = 4/117 (3%)
Query 48 GKVCRVTCKRSGR-KAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
G V + K SG +A ++++ +E+ +++ K+EI++ +LDHP I +L EV+ED
Sbjct 412 GNVLKGVHKESGAVRAIKIILKSKIENAMRM---KREIQIMKTLDHPNIIKLFEVYEDAD 468
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLES 163
+YLV E C GG L+D + S E A + Q+ A+ + V+HR+L+ E+
Sbjct 469 CLYLVMEMCVGGELFDRIVSTNGFSEAYAASIMRQVFSAIAYCHNRNVLHRDLKPEN 525
> mmu:235344 Sik2, G630080D20Rik, Snf1lk2; salt inducible kinase
2 (EC:2.7.11.1)
Length=931
Score = 71.6 bits (174), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 36/101 (35%), Positives = 60/101 (59%), Gaps = 0/101 (0%)
Query 66 VVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLA 125
++ K D + LE + +E+++ LDHP+I +L +V E +YLV+EY G ++D+LA
Sbjct 50 IIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLA 109
Query 126 SLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+ + E AR Q++ AV + G VVHR+L+ E+ L
Sbjct 110 NHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLL 150
> ath:AT5G01810 CIPK15; CIPK15 (CBL-INTERACTING PROTEIN KINASE
15); kinase/ protein kinase
Length=421
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 44/121 (36%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query 78 ETLKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVART 137
E +K+EI L HP I L EV +Y V E+ GG L++ + S K E+VAR
Sbjct 55 EQIKREISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARK 113
Query 138 WTLQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAAC 197
+ Q+VRAV F GV HR+L+ E+ L + G + +GLS + +++G L+ C
Sbjct 114 YFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNL-KISDFGLSALSDSRRQDGLLHTTC 172
Query 198 G 198
G
Sbjct 173 G 173
> cpv:cgd2_1300 calcium/calmodulin dependent protein kinase with
a kinase domain and 4 calmodulin like EF hands ; K13412 calcium-dependent
protein kinase [EC:2.7.11.1]
Length=677
Score = 71.2 bits (173), Expect = 2e-12, Method: Composition-based stats.
Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 4/134 (2%)
Query 31 IGNAYSFDFCVLRREDAGKVCRVTCKRSG-RKAEALVVRKHLEDPLQLETLKKEIEVWLS 89
I + Y + L R G V + K+SG ++A ++++ LE+ + LK+EI +
Sbjct 180 INDFYELNLGNLGRGSYGSVVKAIDKQSGAQRAVKIILKPKLEN---INRLKREILIMKR 236
Query 90 LDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFL 149
LDHP I +L EVFED +Y V E C GG L+D + E A Q+ A+ +
Sbjct 237 LDHPNIIKLFEVFEDTNYLYFVMEICTGGELFDRIIKRGHFSERYAAVIMRQVFSAIAYC 296
Query 150 QGCGVVHRNLRLES 163
+HR+L+ E+
Sbjct 297 HSNEFMHRDLKPEN 310
> ath:AT5G45810 CIPK19; CIPK19 (CBL-INTERACTING PROTEIN KINASE
19); ATP binding / kinase/ protein kinase/ protein serine/threonine
kinase
Length=483
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 46/156 (29%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query 48 GKVCRVTCKRSGRKAEALVVR-----KHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVF 102
G +V R+ + E++ ++ K L+ L + +K+EI + + HP I +L EV
Sbjct 37 GTFAKVYLARNAQSGESVAIKVIDKEKVLKSGL-IAHIKREISILRRVRHPNIVQLFEVM 95
Query 103 EDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLE 162
+Y V EY GG L++ +A + EE+AR + Q++ AV F GV HR+L+ E
Sbjct 96 ATKSKIYFVMEYVKGGELFNKVAK-GRLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPE 154
Query 163 SWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
+ L + G + +GLS + +++G + CG
Sbjct 155 NLLLDENGNL-KVSDFGLSAVSDQIRQDGLFHTFCG 189
> cel:K07A9.2 cmk-1; CaM Kinase family member (cmk-1); K08794
calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
Length=348
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 53/175 (30%), Positives = 87/175 (49%), Gaps = 19/175 (10%)
Query 27 MRDFIGN-AYSFDFCVLRREDAGKVCRVTCKRSGRKAEALVVRKHLEDPLQLETLKKEIE 85
RD +G A+S F + DAG++ V C + +K L+ + E+L+ EI+
Sbjct 24 FRDVLGTGAFSKVFLAESKSDAGQMYAVKC----------IDKKALKG--KEESLENEIK 71
Query 86 VWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRA 145
V L H I +L + +++ + VYLV E GG L+D + + E+ A Q++ A
Sbjct 72 VLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEA 131
Query 146 VGFLQGCGVVHRNLRLESWQLTKQGCFPPLKL--YGLSHSTRWHKREGRLNAACG 198
VGF+ GVVHR+L+ E+ Q + + +GLS + + G + ACG
Sbjct 132 VGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKT----EDSGVMATACG 182
> tgo:TGME49_042400 calcium-dependent protein kinase, putative
(EC:2.7.11.17); K13412 calcium-dependent protein kinase [EC:2.7.11.1]
Length=604
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query 48 GKVCRVTCKRSGR-KAEALVVRKHLEDPLQLETLKKEIEVWLSLDHPYIARLLEVFEDDR 106
G VCR K + +A + + +++ ++ K+EI + LDHP I +L E FED +
Sbjct 141 GSVCRAVNKATKNVRAVKTIPKAKVKN---IKRFKQEIAIMKCLDHPNIIKLYETFEDHK 197
Query 107 AVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQMVRAVGFLQGCGVVHRNLRLESWQL 166
+YLV E C GG L+D + E A T Q A+ ++ G+ HR+L+ E++
Sbjct 198 NIYLVLELCKGGELFDRIIEEGYFSEMYAGTLMRQAFAALYYIHQHGIAHRDLKPENFLF 257
Query 167 TKQGCFPPLKLYGLSHSTR 185
+ PLK+ + R
Sbjct 258 ADKSKEAPLKIIDFGLAAR 276
> ath:AT1G30270 CIPK23; CIPK23 (CBL-INTERACTING PROTEIN KINASE
23); kinase/ protein binding / protein serine/threonine kinase;
K00924 [EC:2.7.1.-]
Length=482
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 37/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
Query 80 LKKEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWT 139
+K+EI + HP + R+ EV +Y V E+ GG L+D ++S + E+ AR +
Sbjct 76 IKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYF 135
Query 140 LQMVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKLYGLSHSTRWHKREGRLNAACG 198
Q++ AV + GV HR+L+ E+ L G + +GLS + + +G L+ CG
Sbjct 136 QQLINAVDYCHSRGVYHRDLKPENLLLDANGAL-KVSDFGLSALPQQVREDGLLHTTCG 193
> tpv:TP01_0983 calcium-dependent protein kinase; K13412 calcium-dependent
protein kinase [EC:2.7.11.1]
Length=509
Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 2/114 (1%)
Query 82 KEIEVWLSLDHPYIARLLEVFEDDRAVYLVSEYCPGGSLYDFLASLQKCPEEVARTWTLQ 141
+E++ LDHP IARL +V+ED A Y+V E C GG L+D + Q+ E + Q
Sbjct 101 REVKYLKELDHPNIARLYDVYEDSVAYYIVMEPCYGGELFDEIIKRQRITEHESACLIKQ 160
Query 142 MVRAVGFLQGCGVVHRNLRLESWQLTKQGCFPPLKL--YGLSHSTRWHKREGRL 193
++ V +L +VHR+L+ E+ L K G +K+ +GLS H + RL
Sbjct 161 ILSGVCYLHKNNIVHRDLKPENLLLEKPGSLDRIKIVDFGLSAHFGNHVLKERL 214
Lambda K H
0.324 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 6060209704
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40