bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_1070_orf1
Length=131
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_039020 ATP-binding cassette protein subfamily B mem... 123 1e-28
tgo:TGME49_060310 ATP-binding cassette protein subfamily B mem... 118 4e-27
dre:798527 abcb5, im:7158730, mdr1, wu:fc18f02, wu:fi81f06; AT... 99.8 2e-21
mmu:18669 Abcb1b, Abcb1, Mdr1, Mdr1b, Pgy-1, Pgy1, mdr; ATP-bi... 99.8 2e-21
mmu:18671 Abcb1a, Abcb4, Evi32, Mdr1a, Mdr3, P-gp, Pgp, Pgy-3,... 99.4 3e-21
xla:397812 abcb1, xemdr; ATP-binding cassette, sub-family B (M... 97.4 9e-21
hsa:5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-... 93.2 2e-19
cel:C34G6.4 pgp-2; P-GlycoProtein related family member (pgp-2) 93.2 2e-19
dre:100136865 abcb4, zgc:172149; ATP-binding cassette, sub-fam... 92.8 3e-19
hsa:340273 ABCB5, ABCB5alpha, ABCB5beta, EST422562; ATP-bindin... 89.7 2e-18
cel:K08E7.9 pgp-1; P-GlycoProtein related family member (pgp-1) 87.8 9e-18
mmu:27413 Abcb11, ABC16, Bsep, Lith1, PFIC2, PGY4, SPGP; ATP-b... 87.8 9e-18
cel:ZK455.7 pgp-3; P-GlycoProtein related family member (pgp-3) 85.1 6e-17
cel:F42E11.1 pgp-4; P-GlycoProtein related family member (pgp-4) 84.7 6e-17
hsa:8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP... 84.0 1e-16
dre:797269 abcb11a; ATP-binding cassette, sub-family B (MDR/TA... 83.6 1e-16
dre:571189 abcb11b; ATP-binding cassette, sub-family B (MDR/TA... 83.6 2e-16
mmu:18670 Abcb4, Mdr2, Pgy-2, Pgy2, mdr-2; ATP-binding cassett... 83.2 2e-16
hsa:5244 ABCB4, ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3;... 82.4 4e-16
ath:AT5G46540 PGP7; PGP7 (P-GLYCOPROTEIN 7); ATPase, coupled t... 82.4 4e-16
mmu:77706 Abcb5, 9230106F14Rik; ATP-binding cassette, sub-fami... 80.9 9e-16
ath:AT3G62150 PGP21; PGP21 (P-GLYCOPROTEIN 21); ATPase, couple... 80.5 1e-15
ath:AT3G28860 ABCB19; ABCB19; ATPase, coupled to transmembrane... 80.5 1e-15
ath:AT2G47000 ABCB4; ABCB4 (ATP BINDING CASSETTE SUBFAMILY B4)... 80.1 1e-15
cel:F22E10.2 pgp-13; P-GlycoProtein related family member (pgp... 79.7 2e-15
cel:C47A10.1 pgp-9; P-GlycoProtein related family member (pgp-9) 79.3 3e-15
cpv:cgd6_4700 ATP-binding cassette transporter 76.3 2e-14
ath:AT4G01830 PGP5; PGP5 (P-GLYCOPROTEIN 5); ATPase, coupled t... 75.5 5e-14
ath:AT1G02520 PGP11; PGP11 (P-GLYCOPROTEIN 11); ATPase, couple... 75.1 5e-14
ath:AT1G02530 PGP12; PGP12 (P-GLYCOPROTEIN 12); ATPase, couple... 73.2 2e-13
ath:AT2G39480 PGP6; PGP6 (P-GLYCOPROTEIN 6); ATPase, coupled t... 73.2 2e-13
ath:AT4G01820 PGP3; PGP3 (P-GLYCOPROTEIN 3); ATPase, coupled t... 72.8 2e-13
cel:ZK484.2 haf-9; HAlF transporter (PGP related) family membe... 71.6 6e-13
ath:AT3G55320 PGP20; PGP20 (P-GLYCOPROTEIN 20); ATPase, couple... 70.9 9e-13
cel:F22E10.1 pgp-12; P-GlycoProtein related family member (pgp... 70.1 2e-12
cel:F22E10.3 pgp-14; P-GlycoProtein related family member (pgp... 69.3 3e-12
ath:AT3G28360 PGP16; PGP16 (P-GLYCOPROTEIN 16); ATPase, couple... 68.2 7e-12
dre:100330068 ATP-binding cassette, subfamily B, member 1B-like 67.4 1e-11
mmu:74610 Abcb8, 4833412N02Rik, AA409895; ATP-binding cassette... 66.2 2e-11
ath:AT1G28010 PGP14; PGP14 (P-GLYCOPROTEIN 14); ATPase, couple... 65.1 6e-11
ath:AT1G27940 PGP13; PGP13 (P-GLYCOPROTEIN 13); ATPase, couple... 64.7 7e-11
ath:AT1G10680 PGP10; PGP10 (P-GLYCOPROTEIN 10); ATPase, couple... 64.3 9e-11
ath:AT4G18050 PGP9; PGP9 (P-GLYCOPROTEIN 9); ATPase, coupled t... 63.9 1e-10
ath:AT3G28415 P-glycoprotein, putative 63.5 2e-10
ath:AT4G25960 PGP2; PGP2 (P-GLYCOPROTEIN 2); ATPase, coupled t... 62.8 3e-10
ath:AT3G28380 PGP17; PGP17 (P-GLYCOPROTEIN 17); ATP binding / ... 62.4 3e-10
ath:AT2G36910 ABCB1; ABCB1 (ATP BINDING CASSETTE SUBFAMILY B1)... 62.4 4e-10
ath:AT3G28390 PGP18; PGP18 (P-GLYCOPROTEIN 18); ATPase, couple... 62.0 4e-10
cel:W04C9.1 haf-4; HAlF transporter (PGP related) family membe... 60.8 9e-10
hsa:11194 ABCB8, EST328128, M-ABC1, MABC1; ATP-binding cassett... 60.8 1e-09
> tgo:TGME49_039020 ATP-binding cassette protein subfamily B member
2 (EC:3.6.3.30 3.6.3.44); K05658 ATP-binding cassette,
subfamily B (MDR/TAP), member 1
Length=1407
Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 57/127 (44%), Positives = 94/127 (74%), Gaps = 0/127 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
+Q K +YF AI+RQ+MA+FD ++ G+L +R+E++ +IR+ +G+KL+M+ Q ST
Sbjct 171 DRQIARIKLQYFSAILRQDMAYFDMNDAGTLPTRLESDTVTIRNAIGIKLSMMFQFSTVT 230
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
LG L++GFI+SW+LTLV + +P++ G ++ + + K E++TM Y +AGS+SEEA++
Sbjct 231 LGGLVLGFIRSWQLTLVTLSGLPLLVLLGAVLGYCLSKAEQETMPKYKAAGSLSEEALLG 290
Query 121 IRTVVSL 127
IRTVV+L
Sbjct 291 IRTVVAL 297
> tgo:TGME49_060310 ATP-binding cassette protein subfamily B member
1 (EC:3.6.3.44); K05658 ATP-binding cassette, subfamily
B (MDR/TAP), member 1
Length=1345
Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 55/127 (43%), Positives = 85/127 (66%), Gaps = 0/127 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
+QA FK F +I+RQE+ WFD + G+L+S++++N A+IR+ VGLK A +Q +
Sbjct 118 DRQAGKFKLELFSSILRQELGWFDTHDAGALSSQIDSNTATIRTAVGLKCATALQFFSTC 177
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
+G +V F +SWK+TL+ +A +P VA G +AWA+ + ++Y AGSV+EEA+
Sbjct 178 VGGFVVAFWRSWKMTLIVSATLPCVAAGGAFLAWALRYSQTAVSDAYREAGSVAEEALGN 237
Query 121 IRTVVSL 127
IRTV+SL
Sbjct 238 IRTVISL 244
Score = 35.8 bits (81), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 10/127 (7%)
Query 7 FKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSG-VGLKLAMLIQLSTAVLGA 63
+ R F + Q++A+FD +++VG+L S + ++V ++SG G +A+ +S G
Sbjct 821 LRSRAFLQTIHQDVAFFDDPKNSVGALMSTLSSDVLLVKSGSCGNPMALAAVISAITTGC 880
Query 64 LIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVH------KQEKDTMESYSSAGSVSEEA 117
I F+ W+L V ++ V+ M +H K KD ES V EA
Sbjct 881 AI-SFVSDWRLAAVLVTSLLVLVPANIMEERLMHTHDHVSKDSKDRDESLRCPEQVLIEA 939
Query 118 IMAIRTV 124
+ IR V
Sbjct 940 VGGIRVV 946
> dre:798527 abcb5, im:7158730, mdr1, wu:fc18f02, wu:fi81f06;
ATP-binding cassette, sub-family B (MDR/TAP), member 5; K05658
ATP-binding cassette, subfamily B (MDR/TAP), member 1
Length=1340
Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 45/126 (35%), Positives = 79/126 (62%), Gaps = 0/126 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q K +++YF AI+ Q+M+WFD +G L R+ ++ +I G+G K+A+ +Q + +
Sbjct 186 KQTKRIRQKYFHAILHQQMSWFDTHPIGELNIRLTDDINTINDGLGDKIAVFVQFFCSFI 245
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
L++GF+ WKLTLV A P++AG + + + + +Y+ AG+V+EE ++AI
Sbjct 246 SGLVIGFVFGWKLTLVILAVSPLLAGSAAVWSKILASLTSKELTAYAKAGAVAEEILVAI 305
Query 122 RTVVSL 127
RTVV+
Sbjct 306 RTVVAF 311
Score = 67.8 bits (164), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 41/120 (34%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
Query 12 FQAIVRQEMAWFDQSN--VGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+AIVRQE+ WFD +N VG L +++ + + ++ G +L + A+L A+IV F+
Sbjct 855 FKAIVRQEIGWFDDNNNAVGILTTKLATDASLVKGAAGSRLGLATNTICALLIAVIVAFV 914
Query 70 KSWKLTLVCAAAVPVVAG--FGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W+LTL+ A VP + G F + A A H + + + +G +S E + +TVV+L
Sbjct 915 FCWQLTLLILACVPFLTGANFIQLRATAGHTSKDQS--ALEMSGKISTETVENFKTVVAL 972
> mmu:18669 Abcb1b, Abcb1, Mdr1, Mdr1b, Pgy-1, Pgy1, mdr; ATP-binding
cassette, sub-family B (MDR/TAP), member 1B (EC:3.6.3.44);
K05658 ATP-binding cassette, subfamily B (MDR/TAP), member
1
Length=1276
Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 46/127 (36%), Positives = 74/127 (58%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q ++++F AI+ QE+ WFD +VG L +R+ +V+ I G+G K+ M Q T L
Sbjct 141 RQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINDGIGDKIGMFFQSITTFL 200
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
I+GFI WKLTLV A P++ + A + +++Y+ AG+V+EE + AI
Sbjct 201 AGFIIGFISGWKLTLVILAVSPLIGLSSALWAKVLTSFTNKELQAYAKAGAVAEEVLAAI 260
Query 122 RTVVSLA 128
RTV++
Sbjct 261 RTVIAFG 267
Score = 64.7 bits (156), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 39/128 (30%), Positives = 79/128 (61%), Gaps = 14/128 (10%)
Query 10 RY--FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-AL 64
RY F++++RQ+++WFD +++ GSL +R+ ++ +S++ +G +LA++ Q + A LG +
Sbjct 787 RYMVFKSMLRQDISWFDDHKNSTGSLTTRLASDASSVKGAMGARLAVVTQ-NVANLGTGV 845
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHK----QEKDTMESYSSAGSVSEEAIMA 120
I+ + W+LTL+ +P++ GG++ + ++K +E +G ++ EAI
Sbjct 846 ILSLVYGWQLTLLLVVIIPLIV-LGGIIEMKLLSGQALKDKKQLE---ISGKIATEAIEN 901
Query 121 IRTVVSLA 128
RT+VSL
Sbjct 902 FRTIVSLT 909
> mmu:18671 Abcb1a, Abcb4, Evi32, Mdr1a, Mdr3, P-gp, Pgp, Pgy-3,
Pgy3, mdr-3; ATP-binding cassette, sub-family B (MDR/TAP),
member 1A (EC:3.6.3.44); K05658 ATP-binding cassette, subfamily
B (MDR/TAP), member 1
Length=1276
Score = 99.4 bits (246), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 46/127 (36%), Positives = 73/127 (57%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q ++++F AI+ QE+ WFD +VG L +R+ +V+ I G+G K+ M Q
Sbjct 138 RQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFF 197
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
G I+GF + WKLTLV A PV+ G+ A + + +Y+ AG+V+EE + AI
Sbjct 198 GGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAI 257
Query 122 RTVVSLA 128
RTV++
Sbjct 258 RTVIAFG 264
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 41/123 (33%), Positives = 72/123 (58%), Gaps = 6/123 (4%)
Query 10 RY--FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-AL 64
RY F++++RQ+++WFD ++ G+L +R+ + A ++ G +LA++ Q + A LG +
Sbjct 785 RYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQ-NIANLGTGI 843
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I+ I W+LTL+ A VP++A G + + Q + +G ++ EAI RTV
Sbjct 844 IISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTV 903
Query 125 VSL 127
VSL
Sbjct 904 VSL 906
> xla:397812 abcb1, xemdr; ATP-binding cassette, sub-family B
(MDR/TAP), member 1; K05658 ATP-binding cassette, subfamily
B (MDR/TAP), member 1
Length=1287
Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 46/127 (36%), Positives = 77/127 (60%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q K + +F A++RQE+ WFD ++ G L +R+ +V+ I G+G K+AML+Q T ++
Sbjct 152 RQIKKIRSNFFHAVLRQEIGWFDINDAGELNTRLTDDVSKINEGIGDKIAMLLQSLTTLV 211
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
I+GFIK WKLT V A P++ + A + +++Y+ AG+V+EE + +I
Sbjct 212 TGFIIGFIKGWKLTWVMGAISPIMGLSAAIWAKVLSAFTNKELKAYAKAGAVAEEVLSSI 271
Query 122 RTVVSLA 128
RTV +
Sbjct 272 RTVFAFG 278
Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 50/123 (40%), Positives = 79/123 (64%), Gaps = 10/123 (8%)
Query 12 FQAIVRQEMAWFDQS--NVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-ALIVGF 68
F++++RQE+ WFD S + G+L +R+ + + ++ G +LA+L Q + A LG A+I+ F
Sbjct 801 FKSMLRQEIGWFDDSKNSTGALTTRLATDASQVQGATGTRLALLAQ-NVANLGTAIIISF 859
Query 69 IKSWKLTLVCAAAVPVV--AGFGGMVAWAVH-KQEKDTMESYSSAGSVSEEAIMAIRTVV 125
I W+LTL+ A VPV+ AG M +A H K++K +E AG +S +A++ IRTVV
Sbjct 860 IYGWQLTLLILAIVPVIAAAGLVEMKMFAGHAKKDKKELE---KAGKISTDAVLNIRTVV 916
Query 126 SLA 128
SL
Sbjct 917 SLT 919
> hsa:5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, MGC163296,
P-GP, PGY1; ATP-binding cassette, sub-family B (MDR/TAP), member
1 (EC:3.6.3.44); K05658 ATP-binding cassette, subfamily
B (MDR/TAP), member 1
Length=1280
Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 46/127 (36%), Positives = 72/127 (56%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q ++++F AI+RQE+ WFD +VG L +R+ +V+ I G+G K+ M Q
Sbjct 142 RQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFF 201
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
IVGF + WKLTLV A PV+ + A + + +Y+ AG+V+EE + AI
Sbjct 202 TGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAI 261
Query 122 RTVVSLA 128
RTV++
Sbjct 262 RTVIAFG 268
Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 42/123 (34%), Positives = 74/123 (60%), Gaps = 6/123 (4%)
Query 10 RY--FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-AL 64
RY F++++RQ+++WFD ++ G+L +R+ + A ++ +G +LA++ Q + A LG +
Sbjct 789 RYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQ-NIANLGTGI 847
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I+ FI W+LTL+ A VP++A G + + Q + +G ++ EAI RTV
Sbjct 848 IISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTV 907
Query 125 VSL 127
VSL
Sbjct 908 VSL 910
> cel:C34G6.4 pgp-2; P-GlycoProtein related family member (pgp-2)
Length=1272
Score = 93.2 bits (230), Expect = 2e-19, Method: Composition-based stats.
Identities = 42/121 (34%), Positives = 74/121 (61%), Gaps = 0/121 (0%)
Query 7 FKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIV 66
++ Y +AI+RQ++ WFD+ G+L +R+ ++ +R G+G K A+L+Q+ A L V
Sbjct 153 LRQNYLKAILRQQIQWFDKQQTGNLTARLTDDLERVREGLGDKFALLVQMFAAFLAGYGV 212
Query 67 GFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVS 126
GF SW +TLV P++ G ++ ++ + + E+Y+ AG+++EE +IRTV S
Sbjct 213 GFFYSWSMTLVMMGFAPLIVLSGAKMSKSMATRTRVEQETYAVAGAIAEETFSSIRTVHS 272
Query 127 L 127
L
Sbjct 273 L 273
Score = 53.5 bits (127), Expect = 1e-07, Method: Composition-based stats.
Identities = 37/120 (30%), Positives = 65/120 (54%), Gaps = 7/120 (5%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ ++RQ++A++D + G L +R + ++R V +L +++ + GAL +GF
Sbjct 788 FKNLLRQDIAFYDDLRHGTGKLCTRFATDAPNVRY-VFTRLPVVLASIVTICGALGIGFY 846
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVH--KQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W+L L+ VP++ GG + KQ +DT + AG V+ +A+ IRTV SL
Sbjct 847 YGWQLALILVVMVPLLV-MGGYFEMQMRFGKQIRDT-QLLEEAGKVASQAVEHIRTVHSL 904
> dre:100136865 abcb4, zgc:172149; ATP-binding cassette, sub-family
B (MDR/TAP), member 4
Length=650
Score = 92.8 bits (229), Expect = 3e-19, Method: Composition-based stats.
Identities = 45/127 (35%), Positives = 73/127 (57%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q K ++ +F +I++QE+ WFD + G L +R+ +V I G+G KL MLIQ T +
Sbjct 147 RQVKKLRKIFFHSIMKQEIGWFDVNETGQLNTRLTDDVYKINEGIGDKLGMLIQNLTTFI 206
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
+I+GF K WKLTLV A P++ ++ + +Y+ AG+V+EE + +I
Sbjct 207 VGIIIGFAKGWKLTLVILAVSPLLGISAAVIGKVMTTFTSKEQTAYAKAGAVAEEVLSSI 266
Query 122 RTVVSLA 128
RTV +
Sbjct 267 RTVFAFG 273
> hsa:340273 ABCB5, ABCB5alpha, ABCB5beta, EST422562; ATP-binding
cassette, sub-family B (MDR/TAP), member 5; K05660 ATP-binding
cassette, subfamily B (MDR/TAP), member 5
Length=1257
Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 44/127 (34%), Positives = 77/127 (60%), Gaps = 2/127 (1%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQ-LSTAV 60
+Q K ++++F +++ Q++ WFD ++G L +RM ++ I G+G K+A+L Q +ST
Sbjct 134 RQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALLFQNMSTFS 193
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
+G L VG +K WKLTLV + P++ + V + +YS AG+V+EE + +
Sbjct 194 IG-LAVGLVKGWKLTLVTLSTSPLIMASAAACSRMVISLTSKELSAYSKAGAVAEEVLSS 252
Query 121 IRTVVSL 127
IRTV++
Sbjct 253 IRTVIAF 259
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 39/120 (32%), Positives = 70/120 (58%), Gaps = 6/120 (5%)
Query 12 FQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+A++ Q++AWFD+ ++ G L + + ++A I+ G ++ +L Q +T + ++I+ FI
Sbjct 773 FKAMLYQDIAWFDEKENSTGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFI 832
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHK--QEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W++T + + PV+A GM+ A KD E AG ++ EA+ IRT+VSL
Sbjct 833 YGWEMTFLILSIAPVLA-VTGMIETAAMTGFANKDKQE-LKHAGKIATEALENIRTIVSL 890
> cel:K08E7.9 pgp-1; P-GlycoProtein related family member (pgp-1)
Length=1321
Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 48/132 (36%), Positives = 77/132 (58%), Gaps = 10/132 (7%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
+Q + + ++I+RQE++WFD ++ G+LA+++ N+ ++ G G K+ M Q +
Sbjct 165 EQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLFDNLERVKEGTGDKIGMAFQYLSQF 224
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVA--GFG---GMVAWAVHKQEKDTMESYSSAGSVSE 115
+ IV F SW+LTLV A P+ A GF M +A+ ++T+ Y+ AG V E
Sbjct 225 ITGFIVAFTHSWQLTLVMLAVTPIQALCGFAIAKSMSTFAI----RETLR-YAKAGKVVE 279
Query 116 EAIMAIRTVVSL 127
E I +IRTVVSL
Sbjct 280 ETISSIRTVVSL 291
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 70/128 (54%), Gaps = 6/128 (4%)
Query 5 KAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG 62
+ + + F+ ++ Q + +FD Q+ G +++R+ +V ++R+ + + + +I +++
Sbjct 827 RDLRNKLFRNVLSQHIGFFDSPQNASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVA 886
Query 63 ALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWA--VHKQEKDTMESYSSAGSVSEEAIMA 120
+ + F W++ L+ A +P+VA FG + K K E ++ +G ++ EAI
Sbjct 887 GIGLAFFYGWQMALLIIAILPIVA-FGQYLRGRRFTGKNVKSASE-FADSGKIAIEAIEN 944
Query 121 IRTVVSLA 128
+RTV +LA
Sbjct 945 VRTVQALA 952
> mmu:27413 Abcb11, ABC16, Bsep, Lith1, PFIC2, PGY4, SPGP; ATP-binding
cassette, sub-family B (MDR/TAP), member 11; K05664
ATP-binding cassette, subfamily B (MDR/TAP), member 11
Length=1321
Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 40/127 (31%), Positives = 76/127 (59%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q + ++ YF+ I+R E+ WFD ++VG L SR ++ I + ++A+ +Q + L
Sbjct 169 RQIRKMRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQRLSTAL 228
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
L++GF + WKLTLV A P++ ++ +V K + +++Y+ AGS+++E + +I
Sbjct 229 SGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEVLSSI 288
Query 122 RTVVSLA 128
RTV +
Sbjct 289 RTVAAFG 295
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 36/130 (27%), Positives = 73/130 (56%), Gaps = 8/130 (6%)
Query 4 AKAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K ++ F+A++RQ++ WFD ++N G L +R+ + + ++ G ++ M++ T +
Sbjct 828 TKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIF 887
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGM---VAWAVHKQEKDTMESYSSAGSVSEEAI 118
A+++ F+ +WKL+LV + P +A G + + Q+K+ +E AG ++ EA+
Sbjct 888 VAVLIAFLFNWKLSLVISVFFPFLALSGAVQTKMLTGFASQDKEILE---KAGQITNEAL 944
Query 119 MAIRTVVSLA 128
IRTV +
Sbjct 945 SNIRTVAGIG 954
> cel:ZK455.7 pgp-3; P-GlycoProtein related family member (pgp-3)
Length=1268
Score = 85.1 bits (209), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 75/127 (59%), Gaps = 0/127 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
+++ +++Y ++++RQ+ WFD++ +G L +M + + I+ G+G K+ +L+
Sbjct 125 ERRLHCIRKKYLKSVLRQDAKWFDETTIGGLTQKMSSGIEKIKDGIGDKVGVLVGGVATF 184
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
+ + +GF W+LTLV VP+ G + A +++ K+ M +YS+AG ++ E I
Sbjct 185 ISGVSIGFYMCWQLTLVMMITVPLQLGSMYLSAKHLNRATKNEMSAYSNAGGMANEVIAG 244
Query 121 IRTVVSL 127
IRTV++
Sbjct 245 IRTVMAF 251
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Query 12 FQAIVRQEMAWFDQS--NVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ I++Q+ ++FD S NVGSL SR+ + ++++ + +LA ++ ++ + V F
Sbjct 788 FRNIMQQDASYFDDSRHNVGSLTSRLATDAPNVQAAIDQRLAEVLTGIVSLFCGVGVAFY 847
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSLA 128
W + + A ++ VA + + + M+S A + E+I +TV +L
Sbjct 848 YGWNMAPIGLATALLLVVVQSSVAQYLKFRGQRDMDSAIEASRLVTESISNWKTVQALT 906
> cel:F42E11.1 pgp-4; P-GlycoProtein related family member (pgp-4)
Length=1266
Score = 84.7 bits (208), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 39/120 (32%), Positives = 70/120 (58%), Gaps = 0/120 (0%)
Query 8 KERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVG 67
++ Q+++RQ+ WFD++ VG L +M + + I+ G+G K+ +L+ + + +G
Sbjct 130 RKHLLQSVLRQDAKWFDENTVGGLTQKMSSGIEKIKDGIGDKIGVLVSGIATFISGVALG 189
Query 68 FIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
F W+LTLV VP+ G + A +++ K+ M +YSSAG ++ E I IRTV++
Sbjct 190 FYMCWQLTLVMLVTVPLQLGSMYLSAKHLNRATKNEMSAYSSAGGMANEVIAGIRTVIAF 249
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 4/119 (3%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ I++Q+ +FD + NVG+L SR+ + ++++ + +LA ++ ++ + V F
Sbjct 786 FKNIMQQDATYFDDPKHNVGNLTSRLATDSQNVQAAIDHRLAEVLNGVVSLFTGIAVAFW 845
Query 70 KSWKLTLV-CAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W + + A+ +V + + ++ KD MES A + E+I +TV +L
Sbjct 846 FGWSMAPIGLITALLLVIAQSAVAQYLKYRGPKD-MESAIEASRIVTESISNWKTVQAL 903
> hsa:8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP;
ATP-binding cassette, sub-family B (MDR/TAP), member 11;
K05664 ATP-binding cassette, subfamily B (MDR/TAP), member
11
Length=1321
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 38/127 (29%), Positives = 73/127 (57%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q + ++ YF+ I+R E+ WFD ++VG L +R ++ I + ++A+ IQ T+ +
Sbjct 169 RQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQRMTSTI 228
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
++GF + WKLTLV + P++ + +V K +++Y+ AG V++E I ++
Sbjct 229 CGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSM 288
Query 122 RTVVSLA 128
RTV +
Sbjct 289 RTVAAFG 295
Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 34/127 (26%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query 4 AKAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K ++ F+A++ Q++AWFD +++ G+L +R+ + + ++ G ++ M++ T V
Sbjct 828 TKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNSFTNVT 887
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
A+I+ F SWKL+LV P +A G + ++ G ++ EA+ I
Sbjct 888 VAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITNEALSNI 947
Query 122 RTVVSLA 128
RTV +
Sbjct 948 RTVAGIG 954
> dre:797269 abcb11a; ATP-binding cassette, sub-family B (MDR/TAP),
member 11a
Length=1325
Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 43/128 (33%), Positives = 80/128 (62%), Gaps = 2/128 (1%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQ-LSTAV 60
+Q + ++ YF+ I+ E+ WFD ++VG L +RM ++ I + + ++++ I+ +ST +
Sbjct 167 RQIQRIRKTYFRKIMCMEIGWFDCNSVGELNTRMSDDINKINNAIADQVSIFIERISTFI 226
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
G +VGFI WKLTLV A P++ G++A AV + +++Y+ AG+V++E + +
Sbjct 227 FG-FMVGFIGGWKLTLVVIAVSPLLGLAAGLMAMAVARLTGRELKAYAKAGAVADEVLSS 285
Query 121 IRTVVSLA 128
IRTV +
Sbjct 286 IRTVAAFG 293
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 38/123 (30%), Positives = 71/123 (57%), Gaps = 10/123 (8%)
Query 12 FQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
FQA+++QE+ WFD ++ G+L +R+ N + ++ G ++ M++ T + + I+ +
Sbjct 840 FQAMLKQEIGWFDDPMNSPGALTTRLATNASMVQGATGSQIGMIVNSLTNIGASFIIAYY 899
Query 70 KSWKLTLVCAAAVPVVAGFGGM----VAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVV 125
SWKL+LV +P++ G G+ + + ++K +E +AG VS EA+ IRT+
Sbjct 900 FSWKLSLVVTCFLPLI-GLSGVFQSKMLTGLANEDKTALE---AAGQVSSEAMSNIRTIA 955
Query 126 SLA 128
LA
Sbjct 956 GLA 958
> dre:571189 abcb11b; ATP-binding cassette, sub-family B (MDR/TAP),
member 11b; K05664 ATP-binding cassette, subfamily B (MDR/TAP),
member 11
Length=1297
Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 38/127 (29%), Positives = 75/127 (59%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q + ++ YF+ ++R E+ WFD ++VG L +RM ++ I + ++ + IQ T +
Sbjct 133 RQIQIIRKMYFRKVMRMEIGWFDCTSVGELNTRMSDDINKINDAIADQVGIFIQRFTTFV 192
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
++GF + WKLTLV + P++ G++A V K +++Y+ AG+V++E + ++
Sbjct 193 CGFLMGFARGWKLTLVIISVSPLIGIGAGLMALFVAKLTGMELQAYAKAGAVADEVLSSV 252
Query 122 RTVVSLA 128
RTV +
Sbjct 253 RTVAAFG 259
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 41/122 (33%), Positives = 69/122 (56%), Gaps = 8/122 (6%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F A++ QE+ WFD +++ G+L +R+ + + ++ G ++ M++ T + A+I+ F
Sbjct 812 FHAMLGQEIGWFDDRKNSPGALTTRLATDASQVQGATGSQIGMIVNSLTNIGVAVIISFY 871
Query 70 KSWKLTLVCAAAVPVVAGFGGMVA---WAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVS 126
SWKLTL +P +A GG A KQ+K+ ME +AG +S EA+ IRT+
Sbjct 872 FSWKLTLXLLCFLPFLALSGGFQAKMLTGFAKQDKEAME---TAGQISGEALNNIRTIAG 928
Query 127 LA 128
L
Sbjct 929 LG 930
> mmu:18670 Abcb4, Mdr2, Pgy-2, Pgy2, mdr-2; ATP-binding cassette,
sub-family B (MDR/TAP), member 4 (EC:3.6.3.44); K05659
ATP-binding cassette, subfamily B (MDR/TAP), member 4
Length=1276
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 47/127 (37%), Positives = 72/127 (56%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q K ++++F AI+RQEM WFD L +R+ +V+ I G+G K+ M Q
Sbjct 141 RQIKKIRQKFFHAILRQEMGWFDIKGTTELNTRLTDDVSKISEGIGDKVGMFFQAIATFF 200
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
IVGFI+ WKLTLV A P++ + A + + +Y+ AG+V+EEA+ AI
Sbjct 201 AGFIVGFIRGWKLTLVIMAISPILGLSTAVWAKILSTFSDKELAAYAKAGAVAEEALGAI 260
Query 122 RTVVSLA 128
RTV++
Sbjct 261 RTVIAFG 267
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 50/122 (40%), Positives = 80/122 (65%), Gaps = 10/122 (8%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-ALIVGF 68
F+A++RQ+M+WFD +++ G+L++R+ + A ++ G +LA++ Q +TA LG +I+ F
Sbjct 789 FKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQ-NTANLGTGIIISF 847
Query 69 IKSWKLTLVCAAAVPV--VAGFGGMVAWAVH-KQEKDTMESYSSAGSVSEEAIMAIRTVV 125
I W+LTL+ + VP VAG M A + K++K ME +AG ++ EAI IRTVV
Sbjct 848 IYGWQLTLLLLSVVPFIAVAGIVEMKMLAGNAKRDKKEME---AAGKIATEAIENIRTVV 904
Query 126 SL 127
SL
Sbjct 905 SL 906
> hsa:5244 ABCB4, ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3;
ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44);
K05659 ATP-binding cassette, subfamily B (MDR/TAP),
member 4
Length=1279
Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 44/127 (34%), Positives = 74/127 (58%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q + ++++F AI+RQE+ WFD ++ L +R+ +++ I G+G K+ M Q
Sbjct 144 RQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFF 203
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
IVGFI+ WKLTLV A P++ + A + + +Y+ AG+V+EEA+ AI
Sbjct 204 AGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALGAI 263
Query 122 RTVVSLA 128
RTV++
Sbjct 264 RTVIAFG 270
Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 47/123 (38%), Positives = 80/123 (65%), Gaps = 12/123 (9%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG-ALIVGF 68
F+A++RQ+M+WFD +++ G+L++R+ + A ++ G +LA++ Q + A LG +I+ F
Sbjct 792 FKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQ-NIANLGTGIIISF 850
Query 69 IKSWKLTLVCAAAVPVVAGFGGMVAWAV----HKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I W+LTL+ A VP++A G+V + K++K +E +AG ++ EAI IRTV
Sbjct 851 IYGWQLTLLLLAVVPIIA-VSGIVEMKLLAGNAKRDKKELE---AAGKIATEAIENIRTV 906
Query 125 VSL 127
VSL
Sbjct 907 VSL 909
> ath:AT5G46540 PGP7; PGP7 (P-GLYCOPROTEIN 7); ATPase, coupled
to transmembrane movement of substances
Length=1248
Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 40/129 (31%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q+ + Y + I+RQ++ +FD ++N G + RM + I+ +G K+ QL ++
Sbjct 105 ERQSTRIRRLYLKTILRQDIGFFDTETNTGEVIGRMSGDTILIQDSMGEKVGKFTQLVSS 164
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G V FI KLTL VP++ G GG + + + K+ + +Y+ AG+V ++A+
Sbjct 165 FVGGFTVAFIVGMKLTLALLPCVPLIVGTGGAMTYIMSKKAQRVQLAYTEAGNVVQQAVG 224
Query 120 AIRTVVSLA 128
+IRTVV+
Sbjct 225 SIRTVVAFT 233
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 24/136 (17%)
Query 5 KAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLG 62
K + F ++ Q+++WFD +++ G + +R+ + ++++S VG L +++Q ++G
Sbjct 756 KRIRSLSFDRVLHQDISWFDDTKNSSGVIGARLSTDASTVKSIVGDVLGLIMQNMATIIG 815
Query 63 ALIVGFIKSWKLTLVCAAAVPV-----------VAGFGGMVAWAVHKQEKDTMESYSSAG 111
A I+ F +W L L+ PV + GFG A A K Y A
Sbjct 816 AFIIAFTANWLLALMALLVAPVMFFQGYYQIKFITGFG---AKARGK--------YEEAS 864
Query 112 SVSEEAIMAIRTVVSL 127
V+ +A+ +IRTV S
Sbjct 865 QVASDAVSSIRTVASF 880
> mmu:77706 Abcb5, 9230106F14Rik; ATP-binding cassette, sub-family
B (MDR/TAP), member 5; K05660 ATP-binding cassette, subfamily
B (MDR/TAP), member 5
Length=1255
Score = 80.9 bits (198), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 36/127 (28%), Positives = 75/127 (59%), Gaps = 0/127 (0%)
Query 2 QQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
+Q ++++F +I+ Q+++WFD S++ L +RM ++ + G+G K+ ++ Q +
Sbjct 135 RQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLCDGIGDKIPLMFQNISGFS 194
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
L++ IKSWKL+LV + P++ + + + +++YS AG+V+EEA+ +I
Sbjct 195 IGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYSKAGAVAEEALSSI 254
Query 122 RTVVSLA 128
+TV +
Sbjct 255 QTVTAFG 261
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 36/118 (30%), Positives = 69/118 (58%), Gaps = 2/118 (1%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+A++ Q+MAW+D ++N G+L + + +VA I+ +L ++ Q + + ++++ FI
Sbjct 774 FKAMLYQDMAWYDDKENNTGALTTTLAVDVAQIQGAATSRLGIVTQDVSNMSLSILISFI 833
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W++TL+ + PV+A G + A+ ++ AG ++ EA+ IRTVVSL
Sbjct 834 YGWEMTLLILSFAPVLAVTGMIQTAAMAGFANRDKQALKRAGKIATEAVENIRTVVSL 891
> ath:AT3G62150 PGP21; PGP21 (P-GLYCOPROTEIN 21); ATPase, coupled
to transmembrane movement of substances
Length=1292
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 41/128 (32%), Positives = 71/128 (55%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y Q I+RQ++A+FD ++N G + RM + I+ +G K+ IQL +
Sbjct 151 ERQAGRIRSLYLQTILRQDIAFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLVST 210
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G ++ F + W LTLV +++P++ G +A + K SY+ A V E+ +
Sbjct 211 FIGGFVIAFTEGWLLTLVMVSSIPLLVMSGAALAIVISKMASRGQTSYAKAAVVVEQTVG 270
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 271 SIRTVASF 278
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 38/124 (30%), Positives = 68/124 (54%), Gaps = 18/124 (14%)
Query 12 FQAIVRQEMAWFDQS--NVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ +VR E+ WFD++ + G++ +R+ A+ A++R VG LA +Q +V L++ F+
Sbjct 810 FEKVVRMEVGWFDETENSSGAIGARLSADAATVRGLVGDALAQTVQNLASVTAGLVIAFV 869
Query 70 KSWKLTLVCAAAVPVVAGFGG------MVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRT 123
SW+L + A +P++ G G MV ++ +E A V+ +A+ +IRT
Sbjct 870 ASWQLAFIVLAMLPLI-GLNGYIYMKFMVGFSADAKE---------ASQVANDAVGSIRT 919
Query 124 VVSL 127
V S
Sbjct 920 VASF 923
> ath:AT3G28860 ABCB19; ABCB19; ATPase, coupled to transmembrane
movement of substances / auxin efflux transmembrane transporter
Length=1252
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 74/127 (58%), Gaps = 1/127 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q A +++Y +A+++Q++ +FD + G + + + ++ + K+ I +
Sbjct 113 ERQVAALRKKYLEAVLKQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYLST 172
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
L L+VGF+ +WKL L+ A +P +A GG+ A+ + + ESY++AG ++E+AI
Sbjct 173 FLAGLVVGFVSAWKLALLSVAVIPGIAFAGGLYAYTLTGITSKSRESYANAGVIAEQAIA 232
Query 120 AIRTVVS 126
+RTV S
Sbjct 233 QVRTVYS 239
Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 32/115 (27%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Query 14 AIVRQEMAWFDQS--NVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFIKS 71
AI+R E+ WFD+ N +A+R+ + A ++S + ++++++Q T++L + IV FI
Sbjct 770 AILRNEVGWFDEDEHNSSLIAARLATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVE 829
Query 72 WKLTLVCAAAVP--VVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
W+++L+ P V+A F + ++ DT ++++ ++ E + IRTV
Sbjct 830 WRVSLLILGTFPLLVLANFAQQL--SLKGFAGDTAKAHAKTSMIAGEGVSNIRTV 882
> ath:AT2G47000 ABCB4; ABCB4 (ATP BINDING CASSETTE SUBFAMILY B4);
ATPase, coupled to transmembrane movement of substances
/ xenobiotic-transporting ATPase
Length=1286
Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 72/128 (56%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y + I+RQ++A+FD +N G + RM + I+ +G K+ IQL
Sbjct 132 ERQAARIRSLYLKTILRQDIAFFDIDTNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLLAT 191
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G ++ F++ W LTLV +++P++ G ++A + K +Y+ A +V E+ I
Sbjct 192 FVGGFVIAFVRGWLLTLVMLSSIPLLVMAGALLAIVIAKTASRGQTAYAKAATVVEQTIG 251
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 252 SIRTVASF 259
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 38/118 (32%), Positives = 67/118 (56%), Gaps = 2/118 (1%)
Query 12 FQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ +V E+ WFD+ ++ G++ +R+ A+ A+IR VG LA +Q +++L LI+ F+
Sbjct 800 FEKVVHMEVGWFDEPENSSGTIGARLSADAATIRGLVGDSLAQTVQNLSSILAGLIIAFL 859
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W+L V A +P++A G + + D + Y A V+ +A+ +IRTV S
Sbjct 860 ACWQLAFVVLAMLPLIALNGFLYMKFMKGFSADAKKMYGEASQVANDAVGSIRTVASF 917
> cel:F22E10.2 pgp-13; P-GlycoProtein related family member (pgp-13);
K02021 putative ABC transport system ATP-binding protein
Length=1324
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 35/117 (29%), Positives = 69/117 (58%), Gaps = 0/117 (0%)
Query 8 KERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVG 67
+ RY +I+RQ WFD++ G++ +R+ N+ I+ GVG KL +LI+ + V+ ++++
Sbjct 172 RNRYISSILRQNAGWFDKNLSGTITTRLNDNMERIQDGVGDKLGVLIRGISMVIASVVIS 231
Query 68 FIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I W+L L+ +PV +++ + K + +E AG+++EE +M +RT+
Sbjct 232 LIYEWRLALMMLGLIPVSTICMTLLSRFLEKSTGEELEKVGEAGAIAEECLMGVRTI 288
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 27/120 (22%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Query 7 FKERYFQAIVRQEMAWFDQSN--VGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGAL 64
F+ F+ ++ Q+ A+FD GSL +R+ A+ +++ V ++ ++ + AV+ +
Sbjct 839 FRVAAFRNLLYQDAAYFDNPAHAPGSLITRLAADPPCVKAVVDGRMMQVVYATAAVIACV 898
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
+GFI W++ ++ A + ++ +A+ + + ME+ AG ++ E I ++T+
Sbjct 899 TIGFINCWQVAILGTALIFLLGFIMAGLAFKISIVAAEHMEN-DDAGKIAIEIIENVKTI 957
> cel:C47A10.1 pgp-9; P-GlycoProtein related family member (pgp-9)
Length=1294
Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 35/127 (27%), Positives = 72/127 (56%), Gaps = 0/127 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
++ + F+ ++F +++RQE+AW+D++ G+L++++ N+ +R G G K+ + Q+
Sbjct 132 EKLSNRFRRQFFHSVMRQEIAWYDKNTSGTLSNKLFDNLERVREGTGDKVGLAFQMMAQF 191
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
+G V F W LTL+ + P + G +A + + Y+ AG ++EE + +
Sbjct 192 IGGFAVAFTYDWLLTLIMMSLSPFMMICGLFLAKLLATAATKEAKQYAVAGGIAEEVLTS 251
Query 121 IRTVVSL 127
IRTV++
Sbjct 252 IRTVIAF 258
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query 8 KERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALI 65
+ + ++ ++RQ+ +FD + + G + +R+ + +I+S + +L + +V G L
Sbjct 783 RSKVYRNVLRQDATYFDMPKHSPGRITTRLATDAPNIKSAIDYRLGSIFNAIASVGGGLG 842
Query 66 VGFIKSWKLTLVCAAAVPVVA-GFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
+ F W++ + A P +A G M+ + D E +AG + EAI IRTV
Sbjct 843 IAFYYGWQMAFLVMAIFPFMAVGQALMMKYHGGSATSDAKE-MENAGKTAMEAIENIRTV 901
Query 125 VSL 127
+L
Sbjct 902 QAL 904
> cpv:cgd6_4700 ATP-binding cassette transporter
Length=1283
Score = 76.3 bits (186), Expect = 2e-14, Method: Composition-based stats.
Identities = 42/123 (34%), Positives = 70/123 (56%), Gaps = 2/123 (1%)
Query 5 KAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGAL 64
K K FQ I++ + W ++ GS++S++ AN A IR G G+K + LI + L
Sbjct 135 KDIKRESFQYILQMDEDWHRDNDCGSVSSKIIANCALIREGYGIKFSQLISNVSQFLFGF 194
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMES-YSSAGSVSEEAIMAIRT 123
IVGF + WK+ LV +A++P+VA G ++ +H+ T + YS +G+++ E I+
Sbjct 195 IVGFYRGWKMALVMSASLPIVAAAGFLIT-KIHRSWGTTTQRVYSKSGALAFETFNNIKL 253
Query 124 VVS 126
V S
Sbjct 254 VKS 256
> ath:AT4G01830 PGP5; PGP5 (P-GLYCOPROTEIN 5); ATPase, coupled
to transmembrane movement of substances
Length=1230
Score = 75.5 bits (184), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 38/128 (29%), Positives = 69/128 (53%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y + I+RQ++ +FD + G + RM + I +G K+ IQL +
Sbjct 101 ERQAARIRSLYLKTILRQDIGFFDVEMTTGEVVGRMSGDTVLILDAMGEKVGKFIQLIST 160
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G ++ F++ W LTLV ++P++A G +A V + +Y+ A +V E+ +
Sbjct 161 FVGGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAIIVTRASSQEQAAYAKASNVVEQTLG 220
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 221 SIRTVASF 228
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 4/119 (3%)
Query 12 FQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ +V E+ WFD+ ++ G++ +R+ A+ A IR+ VG L + ++ +++ LI+ F
Sbjct 743 FEKVVHMEVGWFDEPGNSSGAMGARLSADAALIRTLVGDSLCLSVKNVASLVTGLIIAFT 802
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQ-EKDTMESYSSAGSVSEEAIMAIRTVVSL 127
SW++ ++ + G G + K D Y A V+ +A+ +IRTV S
Sbjct 803 ASWEVAIIILVII-PFIGINGYIQIKFMKGFSADAKAKYEEASQVANDAVGSIRTVASF 860
> ath:AT1G02520 PGP11; PGP11 (P-GLYCOPROTEIN 11); ATPase, coupled
to transmembrane movement of substances
Length=1278
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 42/128 (32%), Positives = 72/128 (56%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y + I+RQ++ +FD ++N G + RM + I+ +G K+ IQL +
Sbjct 129 ERQAARIRSTYLKTILRQDIGFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVST 188
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G ++ FIK W LTLV ++P++A G +A V + +Y+ A +V E+ I
Sbjct 189 FVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAMALIVTRASSRGQAAYAKAATVVEQTIG 248
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 249 SIRTVASF 256
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ V E+AWFD Q++ G++ +R+ A+ IR+ VG L++ +Q + LI+ F
Sbjct 790 FEKAVHMEVAWFDEPQNSSGTMGARLSADATLIRALVGDALSLAVQNVASAASGLIIAFT 849
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQ-EKDTMESYSSAGSVSEEAIMAIRTVVSL 127
SW+L L+ +P++ G G V K D Y A V+ +A+ +IRTV S
Sbjct 850 ASWELALIILVMLPLI-GINGFVQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASF 907
> ath:AT1G02530 PGP12; PGP12 (P-GLYCOPROTEIN 12); ATPase, coupled
to transmembrane movement of substances
Length=1273
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 41/128 (32%), Positives = 69/128 (53%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y + I+RQ++ +FD ++N G + RM + I+ +G K+ IQL +
Sbjct 116 ERQAAKIRSNYLKTILRQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQLVST 175
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G + F K W LTLV ++P +A G +A V + +Y+ A +V E+ I
Sbjct 176 FVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVEQTIG 235
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 236 SIRTVASF 243
Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 36/119 (30%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Query 12 FQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ V E++WFD+ ++ G++ +R+ + A IR+ VG L++ +Q + + LI+ F
Sbjct 785 FEKAVHMEVSWFDEPENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFT 844
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQ-EKDTMESYSSAGSVSEEAIMAIRTVVSL 127
SW+L L+ +P++ G G + K D Y A V+ +A+ +IRTV S
Sbjct 845 ASWELALIILVMLPLI-GINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASF 902
> ath:AT2G39480 PGP6; PGP6 (P-GLYCOPROTEIN 6); ATPase, coupled
to transmembrane movement of substances
Length=1407
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 33/128 (25%), Positives = 72/128 (56%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ-SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q + +Y Q ++ Q+M++FD N G + S++ ++V I+S + K+ I
Sbjct 162 ERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT 221
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ LI+GF+ W++ L+ A P + GG+ +H+ ++ ++Y+ A S++E+A+
Sbjct 222 FISGLIIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEAASIAEQAVS 281
Query 120 AIRTVVSL 127
+RT+ +
Sbjct 282 YVRTLYAF 289
Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats.
Identities = 34/129 (26%), Positives = 67/129 (51%), Gaps = 2/129 (1%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLST 58
++ + + F A++R E+ W+D+ ++ +L+ R+ + +R+ +L++ IQ S
Sbjct 905 EKMTERVRRMMFSAMLRNEVGWYDEEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSF 964
Query 59 AVLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
AV+ A+++G + W+L LV A +PV+ + K E + A V E+A+
Sbjct 965 AVIVAILIGLLLGWRLALVALATLPVLTLSAIAQKLWLAGFSKGIQEMHRKASLVLEDAV 1024
Query 119 MAIRTVVSL 127
I TVV+
Sbjct 1025 RNIYTVVAF 1033
> ath:AT4G01820 PGP3; PGP3 (P-GLYCOPROTEIN 3); ATPase, coupled
to transmembrane movement of substances
Length=1229
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 38/128 (29%), Positives = 69/128 (53%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y + I+RQ++ +FD +++ G + RM + I +G K+ IQL
Sbjct 96 ERQAARIRSLYLKTILRQDIGFFDVETSTGEVVGRMSGDTVLILEAMGEKVGKFIQLIAT 155
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+G ++ F+K W LTLV ++P++A G + V + +Y+ A +V E+ +
Sbjct 156 FVGGFVLAFVKGWLLTLVMLVSIPLLAIAGAAMPIIVTRASSREQAAYAKASTVVEQTLG 215
Query 120 AIRTVVSL 127
+IRTV S
Sbjct 216 SIRTVASF 223
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 2/118 (1%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+ +V E+ WFD +++ G++ SR+ A+ A I++ VG L++ ++ + A + LI+ F
Sbjct 742 FEKVVHMEVGWFDDPENSSGTIGSRLSADAALIKTLVGDSLSLSVKNAAAAVSGLIIAFT 801
Query 70 KSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
SWKL ++ +P++ G + + D Y A V+ +A+ +IRTV S
Sbjct 802 ASWKLAVIILVMIPLIGINGYLQIKFIKGFTADAKAKYEEASQVANDAVGSIRTVASF 859
> cel:ZK484.2 haf-9; HAlF transporter (PGP related) family member
(haf-9); K05656 ATP-binding cassette, subfamily B (MDR/TAP),
member 9
Length=815
Score = 71.6 bits (174), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 35/125 (28%), Positives = 69/125 (55%), Gaps = 0/125 (0%)
Query 5 KAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGAL 64
+ + F+++V+QE+ +FD + G + SR+ A+ ++ + + L + +L + T + G+L
Sbjct 277 RQIRNDLFRSVVKQEIGFFDMNKTGEICSRLSADCQTMSNTLSLYMNVLTRNLTMLFGSL 336
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I F SWKL+++ +P++ + ++T S + A V+EE + +IRTV
Sbjct 337 IFMFTLSWKLSMITLINIPIIFLVNKIFGVWYDMLSEETQNSVAKANDVAEEVLSSIRTV 396
Query 125 VSLAC 129
S AC
Sbjct 397 KSFAC 401
> ath:AT3G55320 PGP20; PGP20 (P-GLYCOPROTEIN 20); ATPase, coupled
to transmembrane movement of substances
Length=1408
Score = 70.9 bits (172), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 33/128 (25%), Positives = 71/128 (55%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ-SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q + +Y Q ++ Q+M++FD N G + S++ ++V I+S + K+ I
Sbjct 164 ERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSALSEKVGNYIHNMAT 223
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ L++GF+ W++ L+ A P + GG+ +H+ ++ ++Y+ A ++E+AI
Sbjct 224 FISGLVIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEAAGIAEQAIS 283
Query 120 AIRTVVSL 127
IRT+ +
Sbjct 284 YIRTLYAF 291
Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 65/129 (50%), Gaps = 24/129 (18%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F A++R E+ WFD +++ +L+ R+ + +R+ +L++ IQ S AV+ AL++G +
Sbjct 917 FSAMLRNEVGWFDDEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSFAVIVALLIGLL 976
Query 70 KSWKLTLVCAAAVPV-----------VAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
W+L LV A +P+ +AGF K E + A V E+A+
Sbjct 977 LGWRLALVALATLPILTLSAIAQKLWLAGFS-----------KGIQEMHRKASLVLEDAV 1025
Query 119 MAIRTVVSL 127
I TVV+
Sbjct 1026 RNIYTVVAF 1034
> cel:F22E10.1 pgp-12; P-GlycoProtein related family member (pgp-12);
K02021 putative ABC transport system ATP-binding protein
Length=1318
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 65/117 (55%), Gaps = 0/117 (0%)
Query 8 KERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVG 67
K+ Y Q+I+RQ WFD+++ G+L +++ N+ I G+G KL +LI+ + +++
Sbjct 172 KQHYIQSILRQNAGWFDKNHSGTLTTKLHDNMERINEGIGDKLGVLIRGMVMFVAGIVIS 231
Query 68 FIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
F W+L L+ P+ +++ ++ + AGS++EE++M +RTV
Sbjct 232 FFYEWRLALMMMGIGPLCCVCMSLMSRSMSSFTSKELAGVGKAGSIAEESLMGVRTV 288
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 25/122 (20%), Positives = 64/122 (52%), Gaps = 7/122 (5%)
Query 7 FKERYFQAIVRQEMAWFDQSN--VGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGAL 64
F+ + F+ ++ Q+ ++FD G L +R+ ++ ++++ V ++ +I T++ L
Sbjct 833 FRVQSFKNLLYQDASFFDNPAHAPGKLITRLASDAPNVKAVVDTRMLQVIYSITSITINL 892
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESY--SSAGSVSEEAIMAIR 122
I G+I W++ + A ++ F M+ +K ++ ++ AG ++ E I +++
Sbjct 893 ITGYIFCWRIAI---AGTIMIVLFATMMISMAYKIARENLKQIRKDEAGKIAIEIIESVK 949
Query 123 TV 124
T+
Sbjct 950 TI 951
> cel:F22E10.3 pgp-14; P-GlycoProtein related family member (pgp-14);
K02021 putative ABC transport system ATP-binding protein
Length=1327
Score = 69.3 bits (168), Expect = 3e-12, Method: Composition-based stats.
Identities = 30/117 (25%), Positives = 65/117 (55%), Gaps = 0/117 (0%)
Query 8 KERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVG 67
+ R+ +++RQ WFD+++ G++ +++ ++ IR G+G KL +L++ ++ A++V
Sbjct 184 RHRFVYSVLRQNAGWFDKNHSGTITTKLNDSMERIREGIGDKLGVLLRGFAMLIAAIVVA 243
Query 68 FIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
+I W+L + P ++A + + AGS++EE++M +RTV
Sbjct 244 YIYEWRLASMMLGVAPTCCICMSLLARQMTSTTIKELIGVGKAGSIAEESLMGVRTV 300
> ath:AT3G28360 PGP16; PGP16 (P-GLYCOPROTEIN 16); ATPase, coupled
to transmembrane movement of substances
Length=1228
Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLST 58
++QA +ERY +A++RQ++ +FD ++ + + + ++ I+ + KL ++ ++
Sbjct 94 ERQAAKMRERYLRAVLRQDVGYFDLHVTSTSDIITSVSSDSLVIQDFLSEKLPNILMNAS 153
Query 59 AVLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
A +G+ IVGF+ W+LT+V + ++ G M A+ + E Y+ AGS++E+AI
Sbjct 154 AFVGSYIVGFMLLWRLTIVGFPFIILLLIPGLMYGRALIGISRKIREEYNEAGSIAEQAI 213
Query 119 MAIRTV 124
++RTV
Sbjct 214 SSVRTV 219
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/132 (23%), Positives = 70/132 (53%), Gaps = 12/132 (9%)
Query 4 AKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K +E+ I+ E+ WFD+ ++ G++ SR+ + +RS VG ++++L+Q + V+
Sbjct 731 TKRIREQMLSKILTFEVNWFDEEENSSGAICSRLAKDANVVRSLVGERMSLLVQTISTVM 790
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHK-----QEKDTMESYSSAGSVSEE 116
A +G + +W+ T+V + PV+ +V + + + K + + + ++ E
Sbjct 791 VACTIGLVIAWRFTIVMISVQPVI-----IVCYYIQRVLLKNMSKKAIIAQDESSKLAAE 845
Query 117 AIMAIRTVVSLA 128
A+ IRT+ + +
Sbjct 846 AVSNIRTITTFS 857
> dre:100330068 ATP-binding cassette, subfamily B, member 1B-like
Length=1063
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 41/120 (34%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
Query 12 FQAIVRQEMAWFDQSN--VGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F+AIVRQE+ WFD +N VG L +++ + + ++ G +L + A+L A+IV F+
Sbjct 578 FKAIVRQEIGWFDDNNNAVGILTTKLATDASLVKGAAGSRLGLATNTICALLIAVIVAFV 637
Query 70 KSWKLTLVCAAAVPVVAG--FGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W+LTL+ A VP + G F + A A H + + + +G +S E + +TVV+L
Sbjct 638 FCWQLTLLILACVPFLTGANFIQLRATAGHTSKDQS--ALEMSGKISTETVENFKTVVAL 695
Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 12/24 (50%), Positives = 20/24 (83%), Gaps = 0/24 (0%)
Query 104 MESYSSAGSVSEEAIMAIRTVVSL 127
+ +Y+ AG+V+EE ++AIRTVV+
Sbjct 13 LTAYAKAGAVAEEILVAIRTVVAF 36
> mmu:74610 Abcb8, 4833412N02Rik, AA409895; ATP-binding cassette,
sub-family B (MDR/TAP), member 8; K05655 ATP-binding cassette,
subfamily B (MDR/TAP), member 8
Length=717
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 39/146 (26%), Positives = 73/146 (50%), Gaps = 15/146 (10%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
++ A ++ F +++RQ++A+FD G L SR+ +V +S L ++ ++ T V
Sbjct 203 ERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQV 262
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
+G+L+ + S +LTL+ A P + G G ++ + K + E + A V++EA+
Sbjct 263 IGSLVSLSMLSPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQIARATGVADEALGN 322
Query 121 IRTVVSLA---------------CCC 131
+RTV + A CCC
Sbjct 323 VRTVRAFAMEKREEERYQAELESCCC 348
> ath:AT1G28010 PGP14; PGP14 (P-GLYCOPROTEIN 14); ATPase, coupled
to transmembrane movement of substances
Length=1247
Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 24/131 (18%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F AI+ E+ WFD ++N GSL S + A+ +RS + +L+ ++Q + + AL + F
Sbjct 764 FSAILSNEIGWFDLDENNTGSLTSILAADATLVRSAIADRLSTIVQNLSLTITALALAFF 823
Query 70 KSWKLTLVCAAAVPV-----------VAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
SW++ V A P+ + GFGG D +YS A S++ EAI
Sbjct 824 YSWRVAAVVTACFPLLIAASLTEQLFLKGFGG-----------DYTRAYSRATSLAREAI 872
Query 119 MAIRTVVSLAC 129
IRTV + +
Sbjct 873 SNIRTVAAFSA 883
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 28/125 (22%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q + Y ++I+ +++ +FD ++ + + ++ ++ +G K +++
Sbjct 120 ERQTARLRINYLKSILAKDITFFDTEARDSNFIFHISSDAILVQDAIGDKTGHVLRYLCQ 179
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ ++GF+ W+LTL+ VP++A GG A + + + +Y+ AG V+EE +
Sbjct 180 FIAGFVIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSEAAYADAGKVAEEVMS 239
Query 120 AIRTV 124
+RTV
Sbjct 240 QVRTV 244
> ath:AT1G27940 PGP13; PGP13 (P-GLYCOPROTEIN 13); ATPase, coupled
to transmembrane movement of substances
Length=1245
Score = 64.7 bits (156), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 24/126 (19%)
Query 12 FQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFI 69
F AI+ E+ WFD ++N GSL S + A+ +RS + +L+ ++Q + + AL + F
Sbjct 762 FSAILSNEIGWFDLDENNTGSLTSILAADATLVRSALADRLSTIVQNLSLTVTALALAFF 821
Query 70 KSWKLTLVCAAAVPV-----------VAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
SW++ V A P+ + GFGG D +YS A SV+ EAI
Sbjct 822 YSWRVAAVVTACFPLLIAASLTEQLFLKGFGG-----------DYTRAYSRATSVAREAI 870
Query 119 MAIRTV 124
IRTV
Sbjct 871 ANIRTV 876
Score = 58.2 bits (139), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 29/125 (23%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q + Y ++I+ +++ +FD ++ +L + ++ ++ +G K +++ +
Sbjct 119 ERQTARLRINYLKSILAKDITFFDTEARDSNLIFHISSDAILVQDAIGDKTDHVLRYLSQ 178
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ ++GF+ W+LTL+ VP++A GG A + + + +Y+ AG V+EE +
Sbjct 179 FIAGFVIGFLSVWQLTLLTLGVVPLIAIAGGGYAIVMSTISEKSETAYADAGKVAEEVMS 238
Query 120 AIRTV 124
+RTV
Sbjct 239 QVRTV 243
> ath:AT1G10680 PGP10; PGP10 (P-GLYCOPROTEIN 10); ATPase, coupled
to transmembrane movement of substances
Length=1227
Score = 64.3 bits (155), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 41/124 (33%), Positives = 72/124 (58%), Gaps = 6/124 (4%)
Query 8 KERYFQAIVRQEMAWFDQ-SNVGS-LASRMEANVASIRSGVGLKLAMLIQLSTAVLGALI 65
+++ F AI+R E+ WFD+ N S LASR+E++ +R+ V + +L++ V+ A I
Sbjct 738 RQKMFSAILRNEIGWFDKVDNTSSMLASRLESDATLLRTIVVDRSTILLENLGLVVTAFI 797
Query 66 VGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEK--DTMESYSSAGSVSEEAIMAIRT 123
+ FI +W+LTLV A P++ G ++ + Q + ++Y A ++ E+I IRT
Sbjct 798 ISFILNWRLTLVVLATYPLI--ISGHISEKIFMQGYGGNLSKAYLKANMLAGESISNIRT 855
Query 124 VVSL 127
VV+
Sbjct 856 VVAF 859
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 29/125 (23%), Positives = 65/125 (52%), Gaps = 1/125 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA ++ Y ++++ Q+++ FD + + G + S + + + ++ + K+ + +
Sbjct 113 ERQAAKIRKAYLRSMLSQDISLFDTEISTGEVISAITSEILVVQDAISEKVGNFMHFISR 172
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ +GF W+++LV + VP +A GG+ A+ +SY A ++EE I
Sbjct 173 FIAGFAIGFASVWQISLVTLSIVPFIALAGGIYAFVSSGLIVRVRKSYVKANEIAEEVIG 232
Query 120 AIRTV 124
+RTV
Sbjct 233 NVRTV 237
> ath:AT4G18050 PGP9; PGP9 (P-GLYCOPROTEIN 9); ATPase, coupled
to transmembrane movement of substances
Length=1236
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 36/129 (27%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q+ + Y + I+RQ++ +FD ++N G + RM + I+ +G K+ QL
Sbjct 103 ERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVGKFTQLLCT 162
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
LG + F K L V + +P++ G ++ + K +Y+ AG+V E+ +
Sbjct 163 FLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVAYAEAGNVVEQTVG 222
Query 120 AIRTVVSLA 128
AIRTVV+
Sbjct 223 AIRTVVAFT 231
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query 12 FQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGALIVGFIKS 71
F +V QE++WFD + A+ RS VG LA+++Q V LI+ F +
Sbjct 766 FDKVVHQEISWFD-------------DTANSRSLVGDALALIVQNIATVTTGLIIAFTAN 812
Query 72 WKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTVVSL 127
W L L+ A P + G + D Y A V+ +A+ +IRTV S
Sbjct 813 WILALIVLALSPFIVIQGYAQTKFLTGFSADAKAMYEEASQVANDAVSSIRTVASF 868
> ath:AT3G28415 P-glycoprotein, putative
Length=1221
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 36/126 (28%), Positives = 71/126 (56%), Gaps = 2/126 (1%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLST 58
++QA +E+Y +A++RQ++ +FD ++ + + + ++ I+ + KL + ++
Sbjct 86 ERQASRMREKYLRAVLRQDVGYFDLHVTSTSDVITSVSSDTLVIQDVLSEKLPNFLMSAS 145
Query 59 AVLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
A + + IVGFI W+LT+V ++ G M A+ + E Y+ AGS++E+AI
Sbjct 146 AFVASYIVGFIMLWRLTIVGFPFFILLLIPGLMCGRALINISRKIREEYNEAGSIAEQAI 205
Query 119 MAIRTV 124
+RTV
Sbjct 206 SLVRTV 211
Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/127 (28%), Positives = 68/127 (53%), Gaps = 2/127 (1%)
Query 4 AKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K +E ++ E++WFD+ ++ GS+ SR+ + +RS VG ++++L+Q +AV
Sbjct 726 TKRIRENILSKLLTFEVSWFDEDENSSGSICSRLAKDANVVRSLVGERVSLLVQTISAVS 785
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
A +G SWKL++V A PVV G + K +++ + ++ EA+ I
Sbjct 786 VACTLGLAISWKLSIVMIAIQPVVVGCFYTQRIVLKSISKKAIKAQDESSKLAAEAVSNI 845
Query 122 RTVVSLA 128
RT+ + +
Sbjct 846 RTITAFS 852
> ath:AT4G25960 PGP2; PGP2 (P-GLYCOPROTEIN 2); ATPase, coupled
to transmembrane movement of substances
Length=1273
Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 40/121 (33%), Positives = 70/121 (57%), Gaps = 6/121 (4%)
Query 8 KERYFQAIVRQEMAWFDQ-SNVGS-LASRMEANVASIRSGVGLKLAMLIQLSTAVLGALI 65
+E F+AI++ E+ WFD+ N S LASR+E++ +++ V + +L+Q V+ + I
Sbjct 786 RENMFRAILKNEIGWFDEVDNTSSMLASRLESDATLLKTIVVDRSTILLQNLGLVVTSFI 845
Query 66 VGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEK--DTMESYSSAGSVSEEAIMAIRT 123
+ FI +W+LTLV A P+V G ++ + Q D ++Y A ++ E++ IRT
Sbjct 846 IAFILNWRLTLVVLATYPLV--ISGHISEKLFMQGYGGDLNKAYLKANMLAGESVSNIRT 903
Query 124 V 124
V
Sbjct 904 V 904
Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 30/125 (24%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++QA + Y ++++ Q+++ FD +++ G + S + +++ ++ + K+ + +
Sbjct 149 ERQAAKMRRAYLRSMLSQDISLFDTEASTGEVISAITSDILVVQDALSEKVGNFLHYISR 208
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ +GF W+++LV + VP++A GG+ A+ +SY AG ++EE I
Sbjct 209 FIAGFAIGFTSVWQISLVTLSIVPLIALAGGIYAFVAIGLIARVRKSYIKAGEIAEEVIG 268
Query 120 AIRTV 124
+RTV
Sbjct 269 NVRTV 273
> ath:AT3G28380 PGP17; PGP17 (P-GLYCOPROTEIN 17); ATP binding
/ ATPase/ ATPase, coupled to transmembrane movement of substances
/ nucleoside-triphosphatase/ nucleotide binding
Length=1240
Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 35/126 (27%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLST 58
++QA +E+Y +A++RQ++ +FD ++ + + + ++ I+ + KL + ++
Sbjct 107 ERQAARMREKYLRAVLRQDVGYFDLHVTSTSDVITSISSDSLVIQDFLSEKLPNFLMNAS 166
Query 59 AVLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
A + + IV FI W+LT+V + ++ G M A+ + E Y+ AGS++E+AI
Sbjct 167 AFVASYIVSFILMWRLTIVGFPFIILLLVPGLMYGRALVSISRKIHEQYNEAGSIAEQAI 226
Query 119 MAIRTV 124
++RTV
Sbjct 227 SSVRTV 232
Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 51/84 (60%), Gaps = 2/84 (2%)
Query 4 AKAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K +E+ I+ E+ WFD ++ G++ SR+ + +RS VG ++++L+Q +AV+
Sbjct 745 TKRIREQMLSKILTFEVNWFDIDDNSSGAICSRLAKDANVVRSMVGDRMSLLVQTISAVI 804
Query 62 GALIVGFIKSWKLTLVCAAAVPVV 85
A I+G + +W+L +V + P++
Sbjct 805 IACIIGLVIAWRLAIVMISVQPLI 828
> ath:AT2G36910 ABCB1; ABCB1 (ATP BINDING CASSETTE SUBFAMILY B1);
ATPase, coupled to transmembrane movement of substances
/ auxin efflux transmembrane transporter/ calmodulin binding;
K05658 ATP-binding cassette, subfamily B (MDR/TAP), member
1
Length=1286
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 1/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFD-QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTA 59
++Q + +Y +A + Q++ +FD + + + + ++ + KL I
Sbjct 116 ERQTTKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYMAT 175
Query 60 VLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIM 119
+ IVGF W+L LV A VP++A GG+ + K + ES S AG++ E+ ++
Sbjct 176 FVSGFIVGFTAVWQLALVTLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVV 235
Query 120 AIRTVVSL 127
IR V++
Sbjct 236 QIRVVMAF 243
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 46/74 (62%), Gaps = 2/74 (2%)
Query 5 KAFKERYFQAIVRQEMAWFDQSNVGS--LASRMEANVASIRSGVGLKLAMLIQLSTAVLG 62
K +E+ A+++ EMAWFDQ S +A+R+ + ++RS +G ++++++Q + +L
Sbjct 774 KRVREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLV 833
Query 63 ALIVGFIKSWKLTL 76
A GF+ W+L L
Sbjct 834 ACTAGFVLQWRLAL 847
> ath:AT3G28390 PGP18; PGP18 (P-GLYCOPROTEIN 18); ATPase, coupled
to transmembrane movement of substances
Length=1225
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQ--SNVGSLASRMEANVASIRSGVGLKLAMLIQLST 58
++QA +E+Y +A++RQ++ +FD ++ + + + ++ I+ + KL + ++
Sbjct 95 ERQAAKMREKYLKAVLRQDVGYFDLHVTSTSDVITSVSSDSLVIQDFLSEKLPNFLMNTS 154
Query 59 AVLGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAI 118
A + + IVGF+ W+LT+V + ++ G M A+ + E Y+ AGS++E+ I
Sbjct 155 AFVASYIVGFLLLWRLTIVGFPFIILLLIPGLMYGRALIRISMKIREEYNEAGSIAEQVI 214
Query 119 MAIRTVVSLA 128
++RTV +
Sbjct 215 SSVRTVYAFG 224
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 30/127 (23%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query 4 AKAFKERYFQAIVRQEMAWFD--QSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVL 61
K +ER I+ E+ WFD +++ G++ SR+ + +RS VG ++++L+Q +AV
Sbjct 730 TKRIRERMLGKILTFEVNWFDKDENSSGAICSRLAKDANMVRSLVGDRMSLLVQTISAVS 789
Query 62 GALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAI 121
+G + SW+ ++V + PV+ + ++ ++ + ++ EA+ I
Sbjct 790 ITCAIGLVISWRFSIVMMSVQPVIVVCFYTQRVLLKSMSRNAIKGQDESSKLAAEAVSNI 849
Query 122 RTVVSLA 128
RT+ + +
Sbjct 850 RTITAFS 856
> cel:W04C9.1 haf-4; HAlF transporter (PGP related) family member
(haf-4)
Length=787
Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 31/125 (24%), Positives = 65/125 (52%), Gaps = 0/125 (0%)
Query 5 KAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAVLGAL 64
+A + F +V+Q++A++D G + SR+ A+ ++ V L + + ++ +LG++
Sbjct 253 RAIRYDLFHGLVKQDVAFYDAHKTGEVTSRLAADCQTMSDTVALNVNVFLRNCVMLLGSM 312
Query 65 IVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMAIRTV 124
I SW+L+LV VP++ + + T ++ + + V+EE + +RTV
Sbjct 313 IFMMKLSWRLSLVTFILVPIIFVASKIFGTYYDLLSERTQDTIAESNDVAEEVLSTMRTV 372
Query 125 VSLAC 129
S +C
Sbjct 373 RSFSC 377
> hsa:11194 ABCB8, EST328128, M-ABC1, MABC1; ATP-binding cassette,
sub-family B (MDR/TAP), member 8; K05655 ATP-binding cassette,
subfamily B (MDR/TAP), member 8
Length=718
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 0/128 (0%)
Query 1 QQQAKAFKERYFQAIVRQEMAWFDQSNVGSLASRMEANVASIRSGVGLKLAMLIQLSTAV 60
++ A + F +++RQ++ +FD + G L SR+ +V +S L ++ ++ T V
Sbjct 204 ERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQV 263
Query 61 LGALIVGFIKSWKLTLVCAAAVPVVAGFGGMVAWAVHKQEKDTMESYSSAGSVSEEAIMA 120
G L+ + S +LTL+ A P + G G ++ + K + E + A V++EA+
Sbjct 264 AGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGN 323
Query 121 IRTVVSLA 128
+RTV + A
Sbjct 324 VRTVRAFA 331
Lambda K H
0.322 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2105161088
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40