bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_1629_orf1
Length=89
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_115110 prefoldin subunit 5, putative ; K04797 prefo... 84.0 1e-16
dre:568182 pfdn5, wu:fa09c11, wu:fb38c05, zgc:100894; prefoldi... 61.6 5e-10
mmu:56612 Pfdn5, 1190001O17Rik, 1700010A06Rik, D15Ertd697e, Ei... 60.8 1e-09
hsa:5204 PFDN5, MGC5329, MGC71907, MM-1, MM1, PFD5; prefoldin ... 60.8 1e-09
ath:AT5G23290 PDF5; PDF5 (PREFOLDIN 5); unfolded protein bindi... 55.5 4e-08
tpv:TP01_0102 prefoldin subunit 5; K04797 prefoldin alpha subunit 54.7 6e-08
bbo:BBOV_IV000800 21.m02738; prefoldin subunit 5 (c-myc bindin... 54.7 7e-08
xla:494823 pfdn5; prefoldin subunit 5; K04797 prefoldin alpha ... 53.5 2e-07
sce:YML094W GIM5, PFD5; Gim5p; K04797 prefoldin alpha subunit 40.8 0.001
cel:R151.9 pfd-5; PreFolDin (molecular chaperone) family membe... 40.0 0.002
cpv:cgd5_2430 hypothetical protein ; K04797 prefoldin alpha su... 40.0 0.002
pfa:MAL7P1.94 prefoldin subunit 3, putative 38.1 0.006
pfa:PF11_0292 conserved Plasmodium protein 35.0 0.054
xla:380543 vbp1, MGC64463; von Hippel-Lindau binding protein 1 34.3
mmu:22327 Vbp1; von Hippel-Lindau binding protein 1 32.3
hsa:7411 VBP1, PFD3, PFDN3, VBP-1; von Hippel-Lindau binding p... 32.3 0.42
dre:553651 vbp1, MGC110686, zgc:110686; von Hippel-Lindau bind... 30.4 1.4
cel:T06G6.9 pfd-3; PreFolDin (molecular chaperone) family memb... 29.6 2.4
mmu:381022 Mll2, ALR, BC032281, BC058659, C430014K11Rik, KMT2B... 29.6 2.5
hsa:8085 MLL2, AAD10, ALR, CAGL114, KMT2B, KMT2D, MLL4, TNRC21... 29.6 2.5
tpv:TP01_0927 prefoldin subunit 3 28.5
mmu:100503081 putative transposase element L1Md-A101/L1Md-A102... 28.5 5.9
hsa:221178 SPATA13, ARHGEF29, ASEF2, FLJ31208, FLJ35435, MGC12... 27.7 8.7
cpv:cgd8_740 prefoldin like molecular chaperone 27.7 9.4
> tgo:TGME49_115110 prefoldin subunit 5, putative ; K04797 prefoldin
alpha subunit
Length=178
Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 38/70 (54%), Positives = 55/70 (78%), Gaps = 0/70 (0%)
Query 13 AEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEK 72
AEVLVPLT ++Y KGRL K+LVD+G G++++K C+DAKK +R +++V+EQ K+EK
Sbjct 78 AEVLVPLTSSVYVKGRLVTRKKLLVDVGTGFLIEKNCEDAKKGLDRNVSMVNEQVAKVEK 137
Query 73 MLSEKQKQLE 82
+L EKQ+Q E
Sbjct 138 ILPEKQRQSE 147
> dre:568182 pfdn5, wu:fa09c11, wu:fb38c05, zgc:100894; prefoldin
5; K04797 prefoldin alpha subunit
Length=153
Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 0/80 (0%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
E E+LVPLT ++Y G+L D VLVD+G GY ++K +D K+ +R ++ +++Q K
Sbjct 55 NEGKELLVPLTSSMYVPGKLHDVDHVLVDVGTGYFVEKNVEDGKEFFKRKIDFLTKQIEK 114
Query 70 LEKMLSEKQKQLEVLVATLN 89
++ L EK + +V +N
Sbjct 115 IQPALQEKYAMKQAVVEVMN 134
> mmu:56612 Pfdn5, 1190001O17Rik, 1700010A06Rik, D15Ertd697e,
Eig1, MM-1; prefoldin 5; K04797 prefoldin alpha subunit
Length=154
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 27/69 (39%), Positives = 45/69 (65%), Gaps = 0/69 (0%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
E E+LVPLT ++Y G+L + VL+D+G GY ++KT +DAK +R ++ +++Q K
Sbjct 57 NEGKELLVPLTSSMYVPGKLHDVEHVLIDVGTGYYVEKTAEDAKDFFKRKIDFLTKQMEK 116
Query 70 LEKMLSEKQ 78
++ L EK
Sbjct 117 IQPALQEKH 125
> hsa:5204 PFDN5, MGC5329, MGC71907, MM-1, MM1, PFD5; prefoldin
subunit 5; K04797 prefoldin alpha subunit
Length=154
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 27/69 (39%), Positives = 45/69 (65%), Gaps = 0/69 (0%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
E E+LVPLT ++Y G+L + VL+D+G GY ++KT +DAK +R ++ +++Q K
Sbjct 57 NEGKELLVPLTSSMYVPGKLHDVEHVLIDVGTGYYVEKTAEDAKDFFKRKIDFLTKQMEK 116
Query 70 LEKMLSEKQ 78
++ L EK
Sbjct 117 IQPALQEKH 125
> ath:AT5G23290 PDF5; PDF5 (PREFOLDIN 5); unfolded protein binding;
K04797 prefoldin alpha subunit
Length=151
Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 28/64 (43%), Positives = 41/64 (64%), Gaps = 0/64 (0%)
Query 15 VLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEKML 74
+LVPLT +LY G L DKVLVDIG GY ++KT D K +R +NL+ +L ++
Sbjct 65 MLVPLTASLYVPGTLDEADKVLVDIGTGYFIEKTMDDGKDYCQRKINLLKSNFDQLFEVA 124
Query 75 SEKQ 78
++K+
Sbjct 125 AKKK 128
> tpv:TP01_0102 prefoldin subunit 5; K04797 prefoldin alpha subunit
Length=164
Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 0/76 (0%)
Query 14 EVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEKM 73
++ VPLT +Y G L DKVLV +G GY ++ K A+ ER + V EQ KL+ +
Sbjct 72 QIQVPLTSLVYVPGELTNPDKVLVSVGTGYYVEMDLKKAEDYYERRIRTVEEQMCKLQAI 131
Query 74 LSEKQKQLEVLVATLN 89
LS K KQ+ + + L+
Sbjct 132 LSGKAKQINLSYSYLD 147
> bbo:BBOV_IV000800 21.m02738; prefoldin subunit 5 (c-myc binding
protein); K04797 prefoldin alpha subunit
Length=167
Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 0/73 (0%)
Query 9 KGETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQG 68
++ E+ VPLT +Y G++ KVLV +G GY ++ T A + ER + +V EQ
Sbjct 67 SSQSCEIQVPLTSLVYVPGKIANPGKVLVSVGTGYFIEMTLDKAGEFYERKIEVVEEQLR 126
Query 69 KLEKMLSEKQKQL 81
KL + S K KQ+
Sbjct 127 KLHSICSAKNKQI 139
> xla:494823 pfdn5; prefoldin subunit 5; K04797 prefoldin alpha
subunit
Length=152
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 0/69 (0%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
E ++LVPLT ++Y G L +++D+G GY ++KT +DAK +R + +++Q K
Sbjct 57 NEGKQLLVPLTSSMYVPGTLNDVSTIMIDVGTGYYVEKTVEDAKDFFKRKVEFLTKQIEK 116
Query 70 LEKMLSEKQ 78
++ L EK
Sbjct 117 IQPALQEKH 125
> sce:YML094W GIM5, PFD5; Gim5p; K04797 prefoldin alpha subunit
Length=163
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 43/68 (63%), Gaps = 0/68 (0%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
E ++LVP + +LY G++ + K +VDIG GY ++K+ + A ++ ++ ++++ +
Sbjct 59 NEGQKLLVPASASLYIPGKIVDNKKFMVDIGTGYYVEKSAEAAIAFYQKKVDKLNKESVQ 118
Query 70 LEKMLSEK 77
++ ++ EK
Sbjct 119 IQDIIKEK 126
> cel:R151.9 pfd-5; PreFolDin (molecular chaperone) family member
(pfd-5); K04797 prefoldin alpha subunit
Length=152
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query 10 GETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGK 69
G TA L+PL+ +LY + L K LV+IG GY ++ + AK +R +++Q
Sbjct 62 GHTA--LIPLSESLYIRAELSDPSKHLVEIGTGYFVELDREKAKAIFDRKKEHITKQVET 119
Query 70 LEKMLSEKQK 79
+E +L EK++
Sbjct 120 VEGILKEKRR 129
> cpv:cgd5_2430 hypothetical protein ; K04797 prefoldin alpha
subunit
Length=163
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Query 15 VLVPLTGALYAKGRLQCD-DKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEKM 73
+L P++ ++Y + CD + VLVDIG GY ++ + AK + + ++ + K+ K
Sbjct 75 ILAPISQSIYVDATI-CDVENVLVDIGTGYHVEMRIEKAKVHFDNKIEMIKKSIEKISKS 133
Query 74 LSEKQKQLEVLVATL 88
++K K + + + L
Sbjct 134 FNDKNKIFDAINSIL 148
> pfa:MAL7P1.94 prefoldin subunit 3, putative
Length=192
Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query 14 EVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDA----KKDGERTLNLVSEQQGK 69
E P+ +LYA+G +Q DK+L+ +GA M++ +A + ER +NL E +
Sbjct 92 ETFFPVEESLYARGIVQKTDKILLWLGANVMVEFPFDEATDLLNQHLERAINLSQEMDNE 151
Query 70 L 70
L
Sbjct 152 L 152
> pfa:PF11_0292 conserved Plasmodium protein
Length=248
Score = 35.0 bits (79), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 17/72 (23%), Positives = 38/72 (52%), Gaps = 0/72 (0%)
Query 12 TAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLE 71
+ +V +PLT +Y G++ D LV +G Y +++ + + ++EQ KL+
Sbjct 151 SFDVHIPLTSLVYIPGKIVNTDNFLVRMGTNYYVERNSTQVIEYYNNKIKKINEQITKLK 210
Query 72 KMLSEKQKQLEV 83
+ EK+ ++++
Sbjct 211 ITIIEKKNEIDL 222
> xla:380543 vbp1, MGC64463; von Hippel-Lindau binding protein
1
Length=192
Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 0/63 (0%)
Query 2 HIQRQKQKGETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLN 61
H+Q++K E E L LY K + DKV + +GA ML+ DA+ E+ L+
Sbjct 85 HMQKKKDTTEPMETRFMLADNLYCKASVPPTDKVCLWLGANVMLEYDIDDAQALLEKNLS 144
Query 62 LVS 64
+
Sbjct 145 TAT 147
> mmu:22327 Vbp1; von Hippel-Lindau binding protein 1
Length=196
Score = 32.3 bits (72), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query 2 HIQRQKQKGETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLN 61
++Q++K+ + E L LY K + DKV + +GA ML+
Sbjct 89 YMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYD------------- 135
Query 62 LVSEQQGKLEKMLSEKQKQLEVL 84
+ E Q LEK LS K L+ L
Sbjct 136 -IDEAQALLEKNLSTATKNLDSL 157
> hsa:7411 VBP1, PFD3, PFDN3, VBP-1; von Hippel-Lindau binding
protein 1
Length=197
Score = 32.3 bits (72), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query 2 HIQRQKQKGETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLN 61
++Q++K+ + E L LY K + DKV + +GA ML+
Sbjct 90 YMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYD------------- 136
Query 62 LVSEQQGKLEKMLSEKQKQLEVL 84
+ E Q LEK LS K L+ L
Sbjct 137 -IDEAQALLEKNLSTATKNLDSL 158
> dre:553651 vbp1, MGC110686, zgc:110686; von Hippel-Lindau binding
protein 1
Length=195
Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 0/80 (0%)
Query 2 HIQRQKQKGETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLN 61
H+Q++K + E L +Y K + DKV + +GA ML+ A+ E+ L
Sbjct 86 HMQKKKDTTDPMETHFLLADNVYCKASVPPTDKVCLWLGANVMLEYDIDAAQALLEKNLA 145
Query 62 LVSEQQGKLEKMLSEKQKQL 81
S LE+ L + Q
Sbjct 146 TASRNLDSLEEDLDFLRDQF 165
> cel:T06G6.9 pfd-3; PreFolDin (molecular chaperone) family member
(pfd-3)
Length=185
Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query 11 ETAEVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKL 70
E+ E L+ +Y K +Q +KV + +GA M++ ++A+K L+ + +G +
Sbjct 86 ESFETTFLLSDDVYTKATVQKPEKVSIWLGANVMVEYDLENARK-------LLDKNRGSV 138
Query 71 EKMLSEKQKQLEVL 84
+K++ E +L +
Sbjct 139 QKVVDELTNELSYI 152
> mmu:381022 Mll2, ALR, BC032281, BC058659, C430014K11Rik, KMT2B,
Mll4; myeloid/lymphoid or mixed-lineage leukemia 2 (EC:2.1.1.43);
K09187 histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]
Length=5588
Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 6/40 (15%)
Query 46 QKTCKDAKK-----DGERTLNLVSEQQGKLEKMLSEKQKQ 80
Q+T K A + D E+ L LV+EQQ K++K L + +KQ
Sbjct 3543 QRTAKKAGREFPEADAEK-LKLVTEQQSKIQKQLDQVRKQ 3581
> hsa:8085 MLL2, AAD10, ALR, CAGL114, KMT2B, KMT2D, MLL4, TNRC21;
myeloid/lymphoid or mixed-lineage leukemia 2 (EC:2.1.1.43);
K09187 histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]
Length=5537
Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats.
Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 6/40 (15%)
Query 46 QKTCKDAKK-----DGERTLNLVSEQQGKLEKMLSEKQKQ 80
Q+T K A + D E+ L LV+EQQ K++K L + +KQ
Sbjct 3546 QRTAKKAGREFPEADAEK-LKLVTEQQSKIQKQLDQVRKQ 3584
> tpv:TP01_0927 prefoldin subunit 3
Length=188
Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 14/66 (21%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query 19 LTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEKMLSEKQ 78
++ LY++ R+ + + +GA M++ DA K L+++Q +E+++ E
Sbjct 97 ISDTLYSEARIPYTESAFLWLGANTMVEYPIDDAIK-------LLTDQHNGIEQLIQEMD 149
Query 79 KQLEVL 84
+L+ +
Sbjct 150 VELDWI 155
> mmu:100503081 putative transposase element L1Md-A101/L1Md-A102/L1Md-A2-like
Length=276
Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query 18 PLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLNLVSEQQGKLEKMLSEK 77
P T + G + + +D+ A M+ +D KKD ++L + E K ++L EK
Sbjct 22 PSTPTSPSPGHPNTPENLDLDLKAYLMMM--VEDIKKDFNKSLKEIQENTAKELQVLKEK 79
Query 78 Q----KQLEVLV 85
Q KQ+EVL
Sbjct 80 QENTIKQVEVLT 91
> hsa:221178 SPATA13, ARHGEF29, ASEF2, FLJ31208, FLJ35435, MGC129988,
MGC129989; spermatogenesis associated 13
Length=1277
Score = 27.7 bits (60), Expect = 8.7, Method: Composition-based stats.
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 26/90 (28%)
Query 23 LYAKGRLQCDDKVLVDIGAGY-------------MLQKT-------CKDAKKDGERTLNL 62
LY KGRL D+ LVD+G G ++ +T C ++D R L
Sbjct 1121 LYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQA 1180
Query 63 VSEQQGKLEK------MLSEKQKQLEVLVA 86
++++ ++++ +SE QK+L +L A
Sbjct 1181 CADERRRVQEDKEMGMEISENQKKLAMLNA 1210
> cpv:cgd8_740 prefoldin like molecular chaperone
Length=248
Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 29/48 (60%), Gaps = 0/48 (0%)
Query 14 EVLVPLTGALYAKGRLQCDDKVLVDIGAGYMLQKTCKDAKKDGERTLN 61
E++VPL ++ G + +KVL+ +G+ ++T +++K +R L+
Sbjct 47 EIMVPLGPLAFSPGYIINTNKVLMLLGSDLYAERTTFESQKTIKRRLS 94
Lambda K H
0.312 0.130 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2017039696
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40