bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_2716_orf1
Length=100
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_020100 phosphoribosylpyrophosphate synthetase, puta... 142 3e-34
pfa:PF13_0143 phosphoribosylpyrophosphate synthetase (EC:2.7.6... 138 5e-33
hsa:5631 PRPS1, ARTS, CMTX5, DFN2, DFNX1, KIAA0967, PPRibP, PR... 89.0 4e-18
mmu:328099 Prps1l3, AU021838, AW536152, Gm5081, MGC117905; pho... 88.2 6e-18
hsa:5634 PRPS2, PRSII; phosphoribosyl pyrophosphate synthetase... 88.2 6e-18
mmu:19139 Prps1, 2310010D17Rik, C76571, C76678, Prps-1; phosph... 88.2 6e-18
xla:380347 prps2, MGC53267, prsii; phosphoribosyl pyrophosphat... 88.2 7e-18
mmu:110639 Prps2, 2610101M19Rik, AA589463, AI464149, MGC28388,... 87.8 7e-18
xla:399237 prps1, MGC80806, arts, cmtx5, ppribp, prsi; phospho... 87.8 8e-18
hsa:221823 PRPS1L1, PRPS1, PRPS3, PRPSL, PRS-III; phosphoribos... 87.4 1e-17
mmu:75456 Prps1l1, 1700011K15Rik, MGC130375; phosphoribosyl py... 86.7 2e-17
dre:560827 prps1b, MGC153331, fc64g03, im:6909503, wu:fc64g03,... 86.7 2e-17
cel:R151.2 hypothetical protein; K00948 ribose-phosphate pyrop... 84.7 6e-17
tgo:TGME49_084580 ribose-phosphate pyrophosphokinase, putative... 83.2 2e-16
hsa:5636 PRPSAP2, MGC117304, MGC126719, MGC126721, PAP41; phos... 82.4 3e-16
dre:431746 zgc:91845 79.7 2e-15
mmu:212627 Prpsap2, A230054F23Rik, MGC118451, MGC36957; phosph... 79.0 3e-15
eco:b1207 prs, dnaR, ECK1195, JW1198, prsA; phosphoribosylpyro... 79.0 4e-15
dre:406369 prpsap2, wu:fi14g04, zgc:55477, zgc:85610; phosphor... 77.8 7e-15
xla:380233 prpsap2, MGC53428, prpsap1; phosphoribosyl pyrophos... 77.8 8e-15
hsa:5635 PRPSAP1, PAP39; phosphoribosyl pyrophosphate syntheta... 77.4 9e-15
mmu:67763 Prpsap1, 5730409F23Rik, PAP39; phosphoribosyl pyroph... 77.0 1e-14
xla:379191 prpsap1, MGC53785; phosphoribosyl pyrophosphate syn... 75.9 3e-14
pfa:PF13_0157 ribose-phosphate pyrophosphokinase, putative (EC... 72.0 4e-13
tpv:TP01_0994 phosphoribosylpyrophosphate synthetase; K00948 r... 71.2 7e-13
sce:YOL061W PRS5; 5-phospho-ribosyl-1(alpha)-pyrophosphate syn... 70.1 2e-12
cel:W04G3.5 hypothetical protein 68.6 5e-12
sce:YHL011C PRS3; 5-phospho-ribosyl-1(alpha)-pyrophosphate syn... 67.4 1e-11
ath:AT1G32380 ribose-phosphate pyrophosphokinase 2 / phosphori... 63.2 2e-10
dre:140620 prps1a, MGC111881, cb96, prps1, wu:fb33h12, zgc:552... 58.9 3e-09
sce:YKL181W PRS1, PRP1; 5-phospho-ribosyl-1(alpha)-pyrophospha... 58.9 4e-09
sce:YER099C PRS2; 5-phospho-ribosyl-1(alpha)-pyrophosphate syn... 58.5 5e-09
sce:YBL068W PRS4; 5-phospho-ribosyl-1(alpha)-pyrophosphate syn... 58.2 6e-09
ath:AT2G44530 ribose-phosphate pyrophosphokinase, putative / p... 55.8 3e-08
bbo:BBOV_IV008060 23.m06144; ribose-phosphate pyrophosphokinas... 52.0 5e-07
ath:AT2G42910 ribose-phosphate pyrophosphokinase 4 / phosphori... 33.5 0.16
mmu:213556 Plekhh2, AI256725, E030001K05, MGC159286, mKIAA2028... 30.8 1.0
hsa:130271 PLEKHH2, KIAA2028, PLEKHH1L; pleckstrin homology do... 29.3 2.9
xla:100101308 hypothetical protein LOC100101308; K10652 tripar... 28.9 3.9
ath:AT5G22730 F-box family protein 28.1 6.4
sce:YPR169W JIP5; Essential protein required for biogenesis of... 28.1 7.9
> tgo:TGME49_020100 phosphoribosylpyrophosphate synthetase, putative
(EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=557
Score = 142 bits (357), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 67/85 (78%), Positives = 76/85 (89%), Gaps = 0/85 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
EAAREL+KKGA+RV+AFATHGLFSGPAI+RI+ S LEEVV+TD+IKARP V C +I
Sbjct 470 CEAARELRKKGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDSIKARPEVAECPRITS 529
Query 61 LSISILLADAIRRIHQKESLNDLFN 85
LSIS+LLADAIRRIHQKESLNDLFN
Sbjct 530 LSISVLLADAIRRIHQKESLNDLFN 554
> pfa:PF13_0143 phosphoribosylpyrophosphate synthetase (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=437
Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 65/87 (74%), Positives = 77/87 (88%), Gaps = 0/87 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
EAA++LKK GA+RV+AFATHGLFSGPAIDRI+KS LEEVV+TDT+K+ + SCKKI L
Sbjct 351 EAAKQLKKHGARRVFAFATHGLFSGPAIDRIEKSPLEEVVVTDTVKSNKNIDSCKKITKL 410
Query 62 SISILLADAIRRIHQKESLNDLFNFAS 88
S+S+L+ADAIRRIHQKESLNDLFN S
Sbjct 411 SVSVLVADAIRRIHQKESLNDLFNIKS 437
> hsa:5631 PRPS1, ARTS, CMTX5, DFN2, DFNX1, KIAA0967, PPRibP,
PRSI; phosphoribosyl pyrophosphate synthetase 1 (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=114
Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 42/84 (50%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA RVYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 27 HAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVI 86
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 87 DISMILAEAIRRTHNGESVSYLFS 110
> mmu:328099 Prps1l3, AU021838, AW536152, Gm5081, MGC117905; phosphoribosyl
pyrophosphate synthetase 1-like 3 (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 42/84 (50%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA RVYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 231 HAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVI 290
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 291 DISMILAEAIRRTHNGESVSYLFS 314
> hsa:5634 PRPS2, PRSII; phosphoribosyl pyrophosphate synthetase
2 (EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=321
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 42/84 (50%), Positives = 58/84 (69%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA +VYA THG+FSGPAI RI +A E VV+T+TI + C KI+++
Sbjct 234 HAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVI 293
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 294 DISMILAEAIRRTHNGESVSYLFS 317
> mmu:19139 Prps1, 2310010D17Rik, C76571, C76678, Prps-1; phosphoribosyl
pyrophosphate synthetase 1 (EC:2.7.6.1); K00948 ribose-phosphate
pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 42/84 (50%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA RVYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 231 HAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVI 290
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 291 DISMILAEAIRRTHNGESVSYLFS 314
> xla:380347 prps2, MGC53267, prsii; phosphoribosyl pyrophosphate
synthetase 2 (EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=318
Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 42/83 (50%), Positives = 58/83 (69%), Gaps = 0/83 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA +L GA +VYA THG+FSGPAI RI +A E VV+T+TI + C KI+++
Sbjct 232 AADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQDEKMKQCSKIQVID 291
Query 63 ISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 292 ISMILAEAIRRTHNGESVSYLFS 314
> mmu:110639 Prps2, 2610101M19Rik, AA589463, AI464149, MGC28388,
Prps-2; phosphoribosyl pyrophosphate synthetase 2 (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 42/84 (50%), Positives = 58/84 (69%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA +VYA THG+FSGPAI RI +A E VV+T+TI + C KI+++
Sbjct 231 HAADKLLSAGATKVYAILTHGIFSGPAISRINSAAFEAVVVTNTIPQEDKMKHCSKIQVI 290
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 291 DISMILAEAIRRTHNGESVSYLFS 314
> xla:399237 prps1, MGC80806, arts, cmtx5, ppribp, prsi; phosphoribosyl
pyrophosphate synthetase 1 (EC:2.7.6.1); K00948 ribose-phosphate
pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 87.8 bits (216), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 41/84 (48%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA +VYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 231 HAAEKLLSAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEEKIRHCSKIQVI 290
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 291 DISMILAEAIRRTHNGESVSYLFS 314
> hsa:221823 PRPS1L1, PRPS1, PRPS3, PRPSL, PRS-III; phosphoribosyl
pyrophosphate synthetase 1-like 1 (EC:2.7.6.1); K00948
ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 42/83 (50%), Positives = 57/83 (68%), Gaps = 0/83 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA +L GA RVYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 232 AADKLLSAGATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVID 291
Query 63 ISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 292 ISMILAEAIRRTHNGESVSYLFS 314
> mmu:75456 Prps1l1, 1700011K15Rik, MGC130375; phosphoribosyl
pyrophosphate synthetase 1-like 1 (EC:2.7.6.1); K00948 ribose-phosphate
pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 41/83 (49%), Positives = 58/83 (69%), Gaps = 0/83 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA +L +GA RVYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 232 AADKLLSEGATRVYAILTHGIFSGPAIARINGACFEAVVVTNTIPQEDKMKQCSKIQVID 291
Query 63 ISILLADAIRRIHQKESLNDLFN 85
I+++LA+AIRR H ES++ LF+
Sbjct 292 IAMILAEAIRRTHNGESVSYLFS 314
> dre:560827 prps1b, MGC153331, fc64g03, im:6909503, wu:fc64g03,
zgc:153331; phosphoribosyl pyrophosphate synthetase 1B (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 41/84 (48%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
AA +L GA +VYA THG+FSGPAI RI + E VV+T+TI + C KI+++
Sbjct 231 HAADKLISAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEEKMKHCPKIQVI 290
Query 62 SISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 291 DISMILAEAIRRTHNGESVSYLFS 314
> cel:R151.2 hypothetical protein; K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=446
Score = 84.7 bits (208), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 40/83 (48%), Positives = 57/83 (68%), Gaps = 0/83 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA +L + GA +VYAF HG+FSGPA+ R+ S E VV+T+TI + C KI+ +
Sbjct 359 AADKLVEAGADKVYAFCVHGIFSGPALTRLNASKFEAVVVTNTIPQDENMKKCSKIQCID 418
Query 63 ISILLADAIRRIHQKESLNDLFN 85
IS++LA+AIRR H ES++ LF+
Sbjct 419 ISMILAEAIRRTHNGESVSYLFS 441
> tgo:TGME49_084580 ribose-phosphate pyrophosphokinase, putative
(EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=655
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 40/88 (45%), Positives = 64/88 (72%), Gaps = 3/88 (3%)
Query 4 ARELKKKGAKRVYAFATHG-LFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
A+EL+ GA+R++ ATHG LF G A+DRI KS ++EV++T+T+ P + C+K+ +LS
Sbjct 560 AKELQAGGARRIFMLATHGVLFKG-AVDRINKSPIQEVILTNTVPIPPHIF-CEKLVVLS 617
Query 63 ISILLADAIRRIHQKESLNDLFNFASAP 90
+ L+A+AI+R+H +ESL+ LF + P
Sbjct 618 VGKLMAEAIKRVHAEESLSSLFECRTNP 645
> hsa:5636 PRPSAP2, MGC117304, MGC126719, MGC126721, PAP41; phosphoribosyl
pyrophosphate synthetase-associated protein 2
Length=369
Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 40/82 (48%), Positives = 58/82 (70%), Gaps = 0/82 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA LK++GA +++ ATHGL S A RI++SA++EVV+T+TI C KIK +
Sbjct 281 AAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVD 340
Query 63 ISILLADAIRRIHQKESLNDLF 84
IS++L++AIRRIH ES++ LF
Sbjct 341 ISMILSEAIRRIHNGESMSYLF 362
> dre:431746 zgc:91845
Length=353
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 40/84 (47%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK++GA ++Y ATHGL S A I++SA++EVV+T+T+ C KIK
Sbjct 263 VAAAEILKERGAYKIYIMATHGLLSADAPRLIEESAIDEVVVTNTVPHEVQKLQCPKIKT 322
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ +S++LA+AIRRIH ES+ LF
Sbjct 323 VDVSMILAEAIRRIHNGESMAYLF 346
> mmu:212627 Prpsap2, A230054F23Rik, MGC118451, MGC36957; phosphoribosyl
pyrophosphate synthetase-associated protein 2
Length=369
Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 39/82 (47%), Positives = 57/82 (69%), Gaps = 0/82 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA LK++GA +++ ATHGL S A I++SA++EVV+T+TI C KIK +
Sbjct 281 AAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVD 340
Query 63 ISILLADAIRRIHQKESLNDLF 84
IS++L++AIRRIH ES++ LF
Sbjct 341 ISMILSEAIRRIHNGESMSYLF 362
> eco:b1207 prs, dnaR, ECK1195, JW1198, prsA; phosphoribosylpyrophosphate
synthase (EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=315
Score = 79.0 bits (193), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 37/83 (44%), Positives = 60/83 (72%), Gaps = 0/83 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
+AA LK++GAKRV+A+ATH +FSG A + ++ S ++EVV+ DTI + S ++ L
Sbjct 231 KAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTL 290
Query 62 SISILLADAIRRIHQKESLNDLF 84
++S +LA+AIRRI +ES++ +F
Sbjct 291 TLSGMLAEAIRRISNEESISAMF 313
> dre:406369 prpsap2, wu:fi14g04, zgc:55477, zgc:85610; phosphoribosyl
pyrophosphate synthetase-associated protein 2
Length=357
Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 38/82 (46%), Positives = 57/82 (69%), Gaps = 0/82 (0%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILS 62
AA LK++GA +++ ATHG+ S A I++SA++EVV+T+TI C KIK +
Sbjct 269 AAETLKERGAYKIFVMATHGILSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCPKIKTVD 328
Query 63 ISILLADAIRRIHQKESLNDLF 84
IS++L++AIRRIH ES++ LF
Sbjct 329 ISMILSEAIRRIHNGESMSYLF 350
> xla:380233 prpsap2, MGC53428, prpsap1; phosphoribosyl pyrophosphate
synthetase-associated protein 2
Length=396
Score = 77.8 bits (190), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 40/84 (47%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK++GA +VY ATHG+ S A I+ SA++EVV+T+TI C KI+
Sbjct 306 VAAAEILKERGAFKVYVMATHGILSSDAPRLIELSAIDEVVVTNTIPHELQKQQCSKIRT 365
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ IS++L++AIRRIH ES++ LF
Sbjct 366 VDISLILSEAIRRIHNGESMSYLF 389
> hsa:5635 PRPSAP1, PAP39; phosphoribosyl pyrophosphate synthetase-associated
protein 1
Length=385
Score = 77.4 bits (189), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 38/84 (45%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK++GA ++Y ATHG+ S A I++S+++EVV+T+T+ C KIK
Sbjct 295 VAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKT 354
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ IS++L++AIRRIH ES+ LF
Sbjct 355 VDISLILSEAIRRIHNGESMAYLF 378
> mmu:67763 Prpsap1, 5730409F23Rik, PAP39; phosphoribosyl pyrophosphate
synthetase-associated protein 1
Length=385
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 38/84 (45%), Positives = 56/84 (66%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK++GA ++Y ATHG+ S A I++S ++EVV+T+T+ C KIK
Sbjct 295 VAAAEILKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKT 354
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ IS++L++AIRRIH ES+ LF
Sbjct 355 VDISLILSEAIRRIHNGESMAYLF 378
> xla:379191 prpsap1, MGC53785; phosphoribosyl pyrophosphate synthetase-associated
protein 1 (EC:2.7.6.1)
Length=390
Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 39/84 (46%), Positives = 57/84 (67%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK++GA +VY ATHG+ S A ++ SA++EVV+T+TI C KI+
Sbjct 300 VAAADILKERGAFKVYVMATHGILSSDAPRLLELSAIDEVVVTNTIPHELQKQQCSKIRT 359
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ IS++L++AIRRIH ES++ LF
Sbjct 360 VDISMILSEAIRRIHNGESMSYLF 383
> pfa:PF13_0157 ribose-phosphate pyrophosphokinase, putative (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=560
Score = 72.0 bits (175), Expect = 4e-13, Method: Composition-based stats.
Identities = 34/81 (41%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Query 7 LKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILSISIL 66
LK GA+++Y +ATH + S I++I S ++EVV T+TI P C+K+ ILS++ L
Sbjct 473 LKNAGARKIYLYATHAILSDGCIEKINNSCIDEVVTTNTIHI-PSNICCEKLHILSVAKL 531
Query 67 LADAIRRIHQKESLNDLFNFA 87
+A+ I+R H ++SLN L +F+
Sbjct 532 VAEGIKRAHNEQSLNALEDFS 552
> tpv:TP01_0994 phosphoribosylpyrophosphate synthetase; K00948
ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=325
Score = 71.2 bits (173), Expect = 7e-13, Method: Composition-based stats.
Identities = 35/72 (48%), Positives = 50/72 (69%), Gaps = 0/72 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V+ A LK++GA +VYAF THGLFSGPA+DRI S E+VV+T++IK V K+++
Sbjct 251 VKGADLLKERGALKVYAFVTHGLFSGPAMDRINNSHFEKVVVTNSIKQPETVMKSPKVEV 310
Query 61 LSISILLADAIR 72
L S LA+ ++
Sbjct 311 LDTSEFLANLLK 322
> sce:YOL061W PRS5; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase,
synthesizes PRPP, which is required for nucleotide,
histidine, and tryptophan biosynthesis; one of five related
enzymes, which are active as heteromultimeric complexes (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=496
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 32/84 (38%), Positives = 59/84 (70%), Gaps = 2/84 (2%)
Query 3 AARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKK--IKI 60
AA+ LK +G+ +VYA THG+FSG A++RI +S++++++I++T+ + K + +
Sbjct 409 AAKLLKDQGSTKVYALITHGVFSGDALERIGQSSIDKLIISNTVPQDRTLQYLGKDRVDV 468
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ +S ++ +AIRRIH ES++ LF
Sbjct 469 IDVSCIIGEAIRRIHNGESISMLF 492
> cel:W04G3.5 hypothetical protein
Length=353
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 33/84 (39%), Positives = 51/84 (60%), Gaps = 0/84 (0%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V AA LK +GA ++Y ATHG+ S A ++ S + EV++T+T+ C KIK
Sbjct 263 VAAAEVLKARGAYKIYVIATHGVLSSDAPALLEASPITEVIVTNTVPHDLQKMRCHKIKT 322
Query 61 LSISILLADAIRRIHQKESLNDLF 84
+ +S+++ +AIRRI ES+ LF
Sbjct 323 VDVSLMICEAIRRIFHNESMGQLF 346
> sce:YHL011C PRS3; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase,
synthesizes PRPP, which is required for nucleotide,
histidine, and tryptophan biosynthesis; one of five related
enzymes, which are active as heteromultimeric complexes (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=320
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 35/83 (42%), Positives = 52/83 (62%), Gaps = 0/83 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
+AA L + AK V A THG+ SG AI+ I S L+ VV T+T+ + C K+ ++
Sbjct 233 KAAEILLENRAKSVIAIVTHGVLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVI 292
Query 62 SISILLADAIRRIHQKESLNDLF 84
IS +LA++IRR+H ES++ LF
Sbjct 293 DISSVLAESIRRLHNGESISYLF 315
> ath:AT1G32380 ribose-phosphate pyrophosphokinase 2 / phosphoribosyl
diphosphate synthetase 2 (PRS2) (EC:2.7.6.1); K00948
ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=400
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 31/84 (36%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V+ A L ++GA+ VYA TH +FS PAI+R+ L+EV++T+T+ ++ I
Sbjct 317 VKGAALLHEEGAREVYACCTHAVFSPPAIERLSSGLLQEVIVTNTLPVAEK-NYFPQLTI 375
Query 61 LSISILLADAIRRIHQKESLNDLF 84
LS++ LL + I R+H S++ +F
Sbjct 376 LSVANLLGETIWRVHDDSSVSSIF 399
> dre:140620 prps1a, MGC111881, cb96, prps1, wu:fb33h12, zgc:55299,
zgc:76932; phosphoribosyl pyrophosphate synthetase 1A
(EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=299
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 28/58 (48%), Positives = 36/58 (62%), Gaps = 0/58 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIK 59
AA +L GA +VYA THG+FSGPAI RI + E VV+T+TI + C KI+
Sbjct 231 HAADKLVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQ 288
> sce:YKL181W PRS1, PRP1; 5-phospho-ribosyl-1(alpha)-pyrophosphate
synthetase, synthesizes PRPP, which is required for nucleotide,
histidine, and tryptophan biosynthesis; one of five
related enzymes, which are active as heteromultimeric complexes
(EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=427
Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 33/92 (35%), Positives = 58/92 (63%), Gaps = 3/92 (3%)
Query 1 VEAARELKKK-GAKRVYAFATHGLFSGPAIDRIQKS-ALEEVVITDTIK-ARPMVTSCKK 57
+ AA L + GAK+VY ATHG+F+G ++ ++KS A++ +V+T+T + + KK
Sbjct 335 ISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAIDTIVVTNTYPISGERIAGSKK 394
Query 58 IKILSISILLADAIRRIHQKESLNDLFNFASA 89
+ + +S + A+ IRR H ES++ LF+ +A
Sbjct 395 LVTIDVSPIFAECIRRDHYGESISVLFDSLAA 426
> sce:YER099C PRS2; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase,
synthesizes PRPP, which is required for nucleotide,
histidine, and tryptophan biosynthesis; one of five related
enzymes, which are active as heteromultimeric complexes (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=318
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V+A L GAK V A THG+FSG A +++ S L +V T+T+ P+ +
Sbjct 233 VKACDTLMDHGAKEVIAIVTHGIFSGSAREKLINSRLSRIVCTNTV---PVDLDLDIVDQ 289
Query 61 LSISILLADAIRRIHQKESLNDLFNFA 87
+ IS +A+AIRR+H ES++ LF A
Sbjct 290 VDISPTIAEAIRRLHNGESVSYLFTHA 316
> sce:YBL068W PRS4; 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase,
synthesizes PRPP, which is required for nucleotide,
histidine, and tryptophan biosynthesis; one of five related
enzymes, which are active as heteromultimeric complexes (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=327
Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKI 60
V+A L + GAK V A THG+FSG A ++++ S L +V T+T+ P+
Sbjct 242 VKACDTLMEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTV---PVDLDLPIADQ 298
Query 61 LSISILLADAIRRIHQKESLNDLFNFA 87
+ IS A+AIRR+H ES++ LF A
Sbjct 299 IDISPTFAEAIRRLHNGESVSYLFTHA 325
> ath:AT2G44530 ribose-phosphate pyrophosphokinase, putative /
phosphoribosyl diphosphate synthetase, putative (EC:2.7.6.1);
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
Length=393
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 29/75 (38%), Positives = 45/75 (60%), Gaps = 5/75 (6%)
Query 7 LKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMV--TSCKKIKILSIS 64
L ++GA+ VYA TH +FS PAI R+ +EV+IT+TI P+ ++ +LS++
Sbjct 310 LHQEGAREVYACTTHAVFSPPAISRLSSGLFQEVIITNTI---PLSEKNYFPQLTVLSVA 366
Query 65 ILLADAIRRIHQKES 79
LL + I R+H S
Sbjct 367 NLLGETIWRVHDDCS 381
> bbo:BBOV_IV008060 23.m06144; ribose-phosphate pyrophosphokinase
(EC:2.7.6.1); K00948 ribose-phosphate pyrophosphokinase
[EC:2.7.6.1]
Length=339
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 27/63 (42%), Positives = 41/63 (65%), Gaps = 0/63 (0%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
+AA L GAK V A THG+FSGPA+ RI++S + ++ TD+I V + KI+I+
Sbjct 267 KAAEILITNGAKSVTAVITHGIFSGPALQRIRESPITRILTTDSIAHSESVLAEPKIQII 326
Query 62 SIS 64
S++
Sbjct 327 SLA 329
> ath:AT2G42910 ribose-phosphate pyrophosphokinase 4 / phosphoribosyl
diphosphate synthetase 4 (PRS4) (EC:2.7.6.1)
Length=337
Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 13/82 (15%)
Query 1 VEAARELKKKGAKRVYAFATHGLFSGPAIDRI--QKSALEEVV----ITD----TIKARP 50
+E + L GA +V A+ THG+F + +R +K+ LEE ITD T+KA
Sbjct 258 IECQKVLAAHGAVKVSAYVTHGVFPKSSWERFTHKKNGLEEAFAYFWITDSCPQTVKA-- 315
Query 51 MVTSCKKIKILSISILLADAIR 72
+ + ++LS++ +ADA++
Sbjct 316 -IGNKAPFEVLSLAGSIADALQ 336
> mmu:213556 Plekhh2, AI256725, E030001K05, MGC159286, mKIAA2028;
pleckstrin homology domain containing, family H (with MyTH4
domain) member 2
Length=1491
Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats.
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 6/58 (10%)
Query 40 VVITDTIKARP---MVTSCKKIKILSISILLADAIRRIHQKESLNDLFNFASAPRLQS 94
VV++ K RP ++ + K KIL I++L+A I HQ+++ F+ SAP L S
Sbjct 1408 VVVSTQSKDRPTEKLLFAMAKHKILEITLLIASYINSFHQQKT---TFHHLSAPALLS 1462
> hsa:130271 PLEKHH2, KIAA2028, PLEKHH1L; pleckstrin homology
domain containing, family H (with MyTH4 domain) member 2
Length=1493
Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 7/60 (11%)
Query 40 VVITDT-IKARP---MVTSCKKIKILSISILLADAIRRIHQKESLNDLFNFASAPRLQSA 95
VVI +T K +P ++ + K KIL I++L+A I HQ+++ F+ SAP L SA
Sbjct 1409 VVINNTHSKDKPTEKLLFAMAKPKILEITLLIASYINNFHQQKA---AFHHLSAPALLSA 1465
> xla:100101308 hypothetical protein LOC100101308; K10652 tripartite
motif-containing protein 25
Length=578
Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats.
Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 5/96 (5%)
Query 2 EAARELKKKGAKRVYAFATHGLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKIL 61
E RE++ K A F F G R Q ALE+ V++D + R V C I
Sbjct 210 ERRREMEGKAANETEKFTAQ--FRGI---REQLEALEKRVLSDISRQRERVLLCFSDLIQ 264
Query 62 SISILLADAIRRIHQKESLNDLFNFASAPRLQSASG 97
+ + + R+IH E L ++ + + + A+G
Sbjct 265 QLEMEKEELSRQIHDIEELCNMADPLTVLQAPEANG 300
> ath:AT5G22730 F-box family protein
Length=466
Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats.
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query 22 GLFSGPAIDRIQKSALEEVVITDTIKARPMVTSCKKIKILSISILLADAIR--RIHQ--K 77
G F ++ ++ LEE V + + +++SC +K L I + D ++ R+H
Sbjct 168 GKFEAVSLPCLKTMRLEENVYANDVVLESLISSCPVLKDLIILRMFEDNVKVLRVHSLTL 227
Query 78 ESLNDLFNFASA 89
SLN FNF
Sbjct 228 TSLNIDFNFGEG 239
> sce:YPR169W JIP5; Essential protein required for biogenesis
of the large ribosomal subunit; interacts with proteins involved
in RNA processing, ribosome biogenesis, ubiquitination
and demethylation; similar to WDR55, a human WD repeat protein
Length=492
Score = 28.1 bits (61), Expect = 7.9, Method: Composition-based stats.
Identities = 12/27 (44%), Positives = 21/27 (77%), Gaps = 0/27 (0%)
Query 60 ILSISILLADAIRRIHQKESLNDLFNF 86
I S ++ L+++IR IH +S+ND+F+F
Sbjct 207 INSENLALSNSIRSIHFGDSINDIFHF 233
Lambda K H
0.319 0.131 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2041372988
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40