bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_2785_orf1
Length=190
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.... 284 2e-76
cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehyd... 247 2e-65
ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrog... 247 2e-65
hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehy... 243 4e-64
mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogen... 241 1e-63
sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the li... 240 2e-63
ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP ... 240 2e-63
dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase (E... 239 3e-63
xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1... 239 3e-63
bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase (E... 214 1e-55
tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00... 185 7e-47
pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihy... 161 1e-39
eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydroge... 136 3e-32
ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoa... 117 2e-26
ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrol... 114 1e-25
sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogena... 110 4e-24
eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotid... 100 2e-21
tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putativ... 98.2 2e-20
pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4); ... 95.1 1e-19
tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7) 84.3 2e-16
eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide... 80.5 4e-15
hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin r... 79.0 1e-14
dre:100332932 glutathione reductase-like 77.8 2e-14
mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd... 76.3 5e-14
hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7); K0... 75.5 9e-14
mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione re... 72.4 1e-12
mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:... 71.2 2e-12
mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase 3... 71.2 2e-12
xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1... 69.3 8e-12
xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1... 68.6 1e-11
ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding / gl... 68.6 1e-11
cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr... 65.9 7e-11
cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-... 65.9 9e-11
xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1... 65.1 1e-10
bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9); ... 64.7 2e-10
tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7)... 64.3 2e-10
eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreducta... 64.3 3e-10
hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thior... 63.9 3e-10
dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredo... 63.2 5e-10
tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7)... 63.2 6e-10
cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin red... 60.8 2e-09
tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thior... 60.8 2e-09
sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathio... 60.1 4e-09
xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7); ... 60.1 5e-09
pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thiore... 59.7 5e-09
ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase); ... 58.5 1e-08
cel:C46F11.2 hypothetical protein 53.5 4e-07
hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3 (E... 50.8 3e-06
pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 gluta... 45.4 1e-04
dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathi... 43.9 3e-04
> tgo:TGME49_006470 dihydrolipoyl dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=519
Score = 284 bits (726), Expect = 2e-76, Method: Compositional matrix adjust.
Identities = 134/190 (70%), Positives = 159/190 (83%), Gaps = 0/190 (0%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RPYT++LGLEE+GI+ D+ GRVVV+D+ V Y +I AIGDLI GPMLAHKAEEEGIACV
Sbjct 324 RPYTKNLGLEELGIETDRVGRVVVDDRFCVPNYPNIRAIGDLIRGPMLAHKAEEEGIACV 383
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G+G V ++TIPSVIYTHPE+AGVGKTEE+LKA GVSY +G FPFAANSRARA
Sbjct 384 EMIAGVGEGHVNYETIPSVIYTHPEIAGVGKTEEELKANGVSYNKGTFPFAANSRARAND 443
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
+ G VKVL K++DK+LG WI+GP AGELI + VL MEYGAA+EDLGR C +HPTLSEA
Sbjct 444 VATGFVKVLAHKDSDKLLGAWIMGPEAGELIGQLVLGMEYGAAAEDLGRTCVSHPTLSEA 503
Query 181 LKEACMGCFD 190
+KEACM C+D
Sbjct 504 VKEACMACYD 513
> cel:LLC1.3 hypothetical protein; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=495
Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 120/189 (63%), Positives = 146/189 (77%), Gaps = 2/189 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RPYT LGL + IDLD RGRV VN++ Q K I AIGD+IEGPMLAHKAE+EGI CV
Sbjct 301 RPYTEGLGLSNVQIDLDNRGRVPVNERFQT-KVPSIFAIGDVIEGPMLAHKAEDEGILCV 359
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G + ++ +PSV+YTHPE+A VGK EEQLK EGV+YK G FPF ANSRA+
Sbjct 360 EGIAG-GPVHIDYNCVPSVVYTHPEVAWVGKAEEQLKQEGVAYKIGKFPFVANSRAKTNN 418
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D +G VKVL K+TD++LGV I+GPNAGE+IAEA LAMEYGA++ED+ RVCH HPTLSEA
Sbjct 419 DQEGFVKVLADKQTDRMLGVHIIGPNAGEMIAEATLAMEYGASAEDVARVCHPHPTLSEA 478
Query 181 LKEACMGCF 189
+EA + +
Sbjct 479 FREANLAAY 487
> ath:AT1G48030 mtLPD1; mtLPD1 (mitochondrial lipoamide dehydrogenase
1); ATP binding / dihydrolipoyl dehydrogenase; K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 120/189 (63%), Positives = 150/189 (79%), Gaps = 2/189 (1%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P+T L LE++G++ DK GR++VND+ + + AIGD+I GPMLAHKAEE+G+ACVE
Sbjct 316 PFTSGLDLEKIGVETDKAGRILVNDRF-LSNVPGVYAIGDVIPGPMLAHKAEEDGVACVE 374
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATGD 121
+AGK G V +D +P V+YTHPE+A VGKTEEQLK EGVSY+ G FPF ANSRA+A +
Sbjct 375 FIAGK-HGHVDYDKVPGVVYTHPEVASVGKTEEQLKKEGVSYRVGKFPFMANSRAKAIDN 433
Query 122 SDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEAL 181
++GLVK+L KETDKILGV I+ PNAGELI EAVLA+ Y A+SED+ RVCHAHPT+SEAL
Sbjct 434 AEGLVKILADKETDKILGVHIMAPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAL 493
Query 182 KEACMGCFD 190
KEA M +D
Sbjct 494 KEAAMATYD 502
> hsa:1738 DLD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=509
Score = 243 bits (619), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 116/186 (62%), Positives = 148/186 (79%), Gaps = 2/186 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RP+T++LGLEE+GI+LD RGR+ VN + Q K +I AIGD++ GPMLAHKAE+EGI CV
Sbjct 316 RPFTKNLGLEELGIELDPRGRIPVNTRFQT-KIPNIYAIGDVVAGPMLAHKAEDEGIICV 374
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G + ++ +PSVIYTHPE+A VGK+EEQLK EG+ YK G FPFAANSRA+
Sbjct 375 EGMAG-GAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNA 433
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D+DG+VK+L K TD++LG ILGP AGE++ EA LA+EYGA+ ED+ RVCHAHPTLSEA
Sbjct 434 DTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEA 493
Query 181 LKEACM 186
+EA +
Sbjct 494 FREANL 499
> mmu:13382 Dld, AI315664, AI746344; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 241 bits (614), Expect = 1e-63, Method: Compositional matrix adjust.
Identities = 114/186 (61%), Positives = 149/186 (80%), Gaps = 2/186 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RP+T++LGLEE+GI+LD +GR+ VN++ Q K +I AIGD++ GPMLAHKAE+EGI CV
Sbjct 316 RPFTQNLGLEELGIELDPKGRIPVNNRFQT-KIPNIYAIGDVVAGPMLAHKAEDEGIICV 374
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G + ++ +PSVIYTHPE+A VGK+EEQLK EG+ +K G FPFAANSRA+
Sbjct 375 EGMAG-GAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEFKIGKFPFAANSRAKTNA 433
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D+DG+VK+L K TD++LG ILGP AGE++ EA LA+EYGA+ ED+ RVCHAHPTLSEA
Sbjct 434 DTDGMVKILGHKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEA 493
Query 181 LKEACM 186
+EA +
Sbjct 494 FREANL 499
> sce:YFL018C LPD1, HPD1; Dihydrolipoamide dehydrogenase, the
lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase
and 2-oxoglutarate dehydrogenase multi-enzyme complexes
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 240 bits (612), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 115/190 (60%), Positives = 147/190 (77%), Gaps = 2/190 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RPY LG E++G+++DKRGR+V++D+ K+ HI +GD+ GPMLAHKAEEEGIA V
Sbjct 307 RPYIAGLGAEKIGLEVDKRGRLVIDDQFNS-KFPHIKVVGDVTFGPMLAHKAEEEGIAAV 365
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E L G G V ++ IPSV+Y+HPE+A VGKTEEQLK G+ YK G FPFAANSRA+
Sbjct 366 EMLK-TGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQ 424
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D++G VK+L +T++ILG I+GPNAGE+IAEA LA+EYGA++ED+ RVCHAHPTLSEA
Sbjct 425 DTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEA 484
Query 181 LKEACMGCFD 190
KEA M +D
Sbjct 485 FKEANMAAYD 494
> ath:AT3G17240 mtLPD2; mtLPD2 (LIPOAMIDE DEHYDROGENASE 2); ATP
binding / dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=507
Score = 240 bits (612), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 116/189 (61%), Positives = 148/189 (78%), Gaps = 2/189 (1%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P+T L LE++G++ DK GR++VN++ + + AIGD+I GPMLAHKAEE+G+ACVE
Sbjct 316 PFTSGLDLEKIGVETDKGGRILVNERFST-NVSGVYAIGDVIPGPMLAHKAEEDGVACVE 374
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATGD 121
+AGK G V +D +P V+YT+PE+A VGKTEEQLK EGVSY G FPF ANSRA+A
Sbjct 375 FIAGK-HGHVDYDKVPGVVYTYPEVASVGKTEEQLKKEGVSYNVGKFPFMANSRAKAIDT 433
Query 122 SDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEAL 181
++G+VK+L KETDKILGV I+ PNAGELI EAVLA+ Y A+SED+ RVCHAHPT+SEA+
Sbjct 434 AEGMVKILADKETDKILGVHIMSPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAI 493
Query 182 KEACMGCFD 190
KEA M +D
Sbjct 494 KEAAMATYD 502
> dre:399479 dldh, wu:fb24b05; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=507
Score = 239 bits (611), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 118/186 (63%), Positives = 147/186 (79%), Gaps = 2/186 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RP+T +LGLE +GI+LDKRGR+ VN + Q +I AIGD++ GPMLAHKAE+EGI CV
Sbjct 314 RPFTGNLGLESVGIELDKRGRIPVNGRFQT-NVPNIYAIGDVVAGPMLAHKAEDEGIICV 372
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G + ++ +PSVIYTHPE+A VGKTEEQLK EGV YK G FPFAANSRA+
Sbjct 373 EGMAG-GAVHIDYNCVPSVIYTHPEVAWVGKTEEQLKEEGVPYKVGKFPFAANSRAKTNA 431
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D+DGLVK+L+ K+TD++LG ILG AGE+I EA LAMEYGA+ ED+ RVCHAHPT+SEA
Sbjct 432 DTDGLVKILSHKDTDRMLGAHILGSGAGEMINEAALAMEYGASCEDVARVCHAHPTVSEA 491
Query 181 LKEACM 186
+EA +
Sbjct 492 FREANL 497
> xla:380588 dld, MGC68940; dihydrolipoamide dehydrogenase (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=509
Score = 239 bits (611), Expect = 3e-63, Method: Compositional matrix adjust.
Identities = 115/186 (61%), Positives = 147/186 (79%), Gaps = 2/186 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RP+T +LGL+E+GI+LD RGR+ +N + Q K +I AIGD++ GPMLAHKAE+EGI CV
Sbjct 316 RPFTENLGLQELGIELDNRGRIPINSRFQT-KIPNIYAIGDVVAGPMLAHKAEDEGIICV 374
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
E +AG G + ++ +PSVIYTHPE+A VGK+EEQLK EG YK G FPFAANSRA+
Sbjct 375 EGMAG-GAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGTEYKVGKFPFAANSRAKTNA 433
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D+DGLVK+L+ K TD++LG ILG +AGE+I EA LAMEYGA+ ED+ RVCHAHPT+SEA
Sbjct 434 DTDGLVKILSHKTTDRMLGAHILGASAGEMINEAALAMEYGASCEDVARVCHAHPTVSEA 493
Query 181 LKEACM 186
+EA +
Sbjct 494 FREANL 499
> bbo:BBOV_IV007190 23.m05858; dihydrolipoamide dehydrogenase
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=481
Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 105/186 (56%), Positives = 138/186 (74%), Gaps = 2/186 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RPYT++LGLEE+GI + RG +VV++ ++V Y +I AIGD+I GPMLAHKAEE+G +
Sbjct 289 RPYTKNLGLEELGIKTE-RGYIVVDEMLRVPNYENISAIGDVIAGPMLAHKAEEDGSIAL 347
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATG 120
+ GK G + D IP VIYTHPE+AG+GK+E+ LK+ G+ YK+ FPFAANSRAR G
Sbjct 348 GHILGKDLGHINWDHIPMVIYTHPEVAGIGKSEQVLKSNGIEYKKATFPFAANSRARIAG 407
Query 121 DSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEA 180
D DG VK+L K+ +KILG WI+GP+A ELI + + M G + D+ +VC AHPT+SEA
Sbjct 408 DVDGFVKILADKD-NKILGGWIVGPHASELIGQITIMMACGLTTVDVAKVCFAHPTVSEA 466
Query 181 LKEACM 186
LKEACM
Sbjct 467 LKEACM 472
> tpv:TP03_0227 dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00382
dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=499
Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 94/205 (45%), Positives = 137/205 (66%), Gaps = 21/205 (10%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLK--------YAHIMAIGDLIEGPMLAHKAE 53
PYT LG++++G+ LD G+V ++ ++VLK ++ AIGD+ GPMLAHKAE
Sbjct 289 PYTEGLGIDKLGVTLD-YGKVPTDNNLRVLKDPKDPNSVVENVYAIGDVTYGPMLAHKAE 347
Query 54 EEGIACVERLAGK-----------GDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVS 102
E+G+ + + GK G V + IPSVIYT PE+AGVG+TE+ L+ GV
Sbjct 348 EDGLIALGHILGKSFVHHPQGVTLGSVQVVPNVIPSVIYTEPEIAGVGETEQNLQKLGVK 407
Query 103 YKRGAFPFAANSRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGA 162
YK+ FPF ANSRA+ +SDG +K+L+ +E +K+LG W++GP+ E+I LA+ YGA
Sbjct 408 YKKSVFPFMANSRAKIYNESDGFIKLLSTEE-NKLLGAWMIGPHVSEMIHTTALAITYGA 466
Query 163 ASEDLGRVCHAHPTLSEALKEACMG 187
+SED+ R+C AHP+LSEA+KE+ +G
Sbjct 467 SSEDVTRMCFAHPSLSEAIKESSLG 491
> pfa:PFL1550w lipoamide dehydrogenase (EC:1.8.1.4); K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=512
Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 80/191 (41%), Positives = 117/191 (61%), Gaps = 6/191 (3%)
Query 6 DLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVERL-- 63
+L L + I+L+K ++ V++ V+ I AIGD I+GPMLAHKAEEEG L
Sbjct 317 NLNLHLLNIELNKNKKIPVDEYFNVIAQPTIKAIGDAIDGPMLAHKAEEEGYLLANILFD 376
Query 64 ----AGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARAT 119
K + +D +PSVIYTHPE+A VG E + K +++K +FPFAANSR+R
Sbjct 377 ELKNNKKKKAHINYDLVPSVIYTHPEVATVGYNEAKCKELNMNFKSVSFPFAANSRSRTI 436
Query 120 GDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSE 179
D DGL+K++ K+T++ILG I+G NA +LI + + +S+ L ++ +AHPT SE
Sbjct 437 DDYDGLIKLIVEKDTNRILGSQIIGNNASDLILPLSIYVANNGSSKSLSKIIYAHPTFSE 496
Query 180 ALKEACMGCFD 190
+KE + FD
Sbjct 497 VIKEVALQSFD 507
> eco:b0116 lpd, dhl, ECK0115, JW0112, lpdA; lipoamide dehydrogenase,
E3 component is part of three enzyme complexes (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=474
Score = 136 bits (343), Expect = 3e-32, Method: Compositional matrix adjust.
Identities = 75/184 (40%), Positives = 115/184 (62%), Gaps = 10/184 (5%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P ++L + G+++D RG + V+ +++ HI AIGD++ PMLAHK EG E
Sbjct 275 PNGKNLDAGKAGVEVDDRGFIRVDKQLRT-NVPHIFAIGDIVGQPMLAHKGVHEGHVAAE 333
Query 62 RLAGKGDGTVRH----DTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRAR 117
+AGK +H IPS+ YT PE+A VG TE++ K +G+SY+ FP+AA+ RA
Sbjct 334 VIAGK-----KHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAI 388
Query 118 ATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTL 177
A+ +DG+ K++ KE+ +++G I+G N GEL+ E LA+E G +ED+ HAHPTL
Sbjct 389 ASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTL 448
Query 178 SEAL 181
E++
Sbjct 449 HESV 452
> ath:AT4G16155 dihydrolipoyl dehydrogenase; K00382 dihydrolipoamide
dehydrogenase [EC:1.8.1.4]
Length=630
Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 71/191 (37%), Positives = 108/191 (56%), Gaps = 11/191 (5%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLK-----YAHIMAIGDLIEGPMLAHKAEEEG 56
P+T LGLE + + +RG + V+++M+V+ H+ IGD MLAH A +G
Sbjct 420 PFTNGLGLENINVT-TQRGFIPVDERMRVIDGNGKLVPHLYCIGDANGKLMLAHAASAQG 478
Query 57 IACVERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLK----AEGVSYKRGAFPFAA 112
I+ VE++ G+ D + H +IP+ +THPE++ VG TE Q + EG F A
Sbjct 479 ISVVEQVTGR-DHVLNHLSIPAACFTHPEISMVGLTEPQAREKAEKEGFKVSIAKTSFKA 537
Query 113 NSRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCH 172
N++A A + +GL K++ + +ILGV I G +A +LI EA A+ G +D+ H
Sbjct 538 NTKALAENEGEGLAKMIYRPDNGEILGVHIFGLHAADLIHEASNAIALGTRIQDIKLAVH 597
Query 173 AHPTLSEALKE 183
AHPTLSE + E
Sbjct 598 AHPTLSEVVDE 608
> ath:AT3G16950 LPD1; LPD1 (LIPOAMIDE DEHYDROGENASE 1); dihydrolipoyl
dehydrogenase; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=623
Score = 114 bits (286), Expect = 1e-25, Method: Composition-based stats.
Identities = 71/191 (37%), Positives = 110/191 (57%), Gaps = 11/191 (5%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLK-----YAHIMAIGDLIEGPMLAHKAEEEG 56
P+T LGLE + + + +RG + V+++M+V+ ++ IGD MLAH A +G
Sbjct 360 PFTNGLGLENVNV-VTQRGFIPVDERMRVIDGKGTLVPNLYCIGDANGKLMLAHAASAQG 418
Query 57 IACVERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLK----AEGVSYKRGAFPFAA 112
I+ VE+++G+ D + H +IP+ +THPE++ VG TE Q K EG F A
Sbjct 419 ISVVEQVSGR-DHVLNHLSIPAACFTHPEISMVGLTEPQAKEKGEKEGFKVSVVKTSFKA 477
Query 113 NSRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCH 172
N++A A + +G+ K++ + +ILGV I G +A +LI EA A+ G +D+ H
Sbjct 478 NTKALAENEGEGIAKMIYRPDNGEILGVHIFGLHAADLIHEASNAIALGTRIQDIKLAVH 537
Query 173 AHPTLSEALKE 183
AHPTLSE L E
Sbjct 538 AHPTLSEVLDE 548
> sce:YPL017C IRC15; Irc15p; K00382 dihydrolipoamide dehydrogenase
[EC:1.8.1.4]
Length=499
Score = 110 bits (274), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 66/191 (34%), Positives = 99/191 (51%), Gaps = 7/191 (3%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
RP + L + +G+D V +LKY HI IGD+ GPMLA KAEE+ I +
Sbjct 292 RPLLKGLDISSIGLDERDFVENVDVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAI 351
Query 61 ERLAGKG-DGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARA- 118
+ + G DGT P+V+Y P++ VG TEE L + Y++G F+ N R
Sbjct 352 QSIGCTGSDGTSNCGFPPNVLYCQPQIGWVGYTEEGLAKARIPYQKGRVLFSQNVRYNTL 411
Query 119 -----TGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHA 173
+KVL KILGV ++ +A EL+++A +A+ G + D+ +V
Sbjct 412 LPREENTTVSPFIKVLIDSRDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFP 471
Query 174 HPTLSEALKEA 184
HP+LSE+ K+A
Sbjct 472 HPSLSESFKQA 482
> eco:b3962 sthA, ECK3954, JW5551, sth, udhA; pyridine nucleotide
transhydrogenase, soluble (EC:1.6.1.1); K00322 NAD(P) transhydrogenase
[EC:1.6.1.1]
Length=466
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 67/188 (35%), Positives = 101/188 (53%), Gaps = 6/188 (3%)
Query 4 TRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVERL 63
T L L+ +G++ D RG++ VN Q + H+ A+GD+I P LA A ++G + L
Sbjct 275 TDSLALQNIGLETDSRGQLKVNSMYQTAQ-PHVYAVGDVIGYPSLASAAYDQGRIAAQAL 333
Query 64 AGKGDGTVRH-DTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATGDS 122
KG+ T + IP+ IYT PE++ VGKTE+QL A V Y+ G F +RA+ G +
Sbjct 334 V-KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN 392
Query 123 DGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEY---GAASEDLGRVCHAHPTLSE 179
G +K+L +ET +ILG+ G A E+I ME G E +PT++E
Sbjct 393 VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAE 452
Query 180 ALKEACMG 187
A + A +
Sbjct 453 AYRVAALN 460
> tgo:TGME49_105980 dihydrolipoyl dehydrogenase protein, putative
(EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=636
Score = 98.2 bits (243), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 74/199 (37%), Positives = 110/199 (55%), Gaps = 16/199 (8%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAH-----------IMAIGDLIEGPMLA 49
RP T LGL+ +G+ L + G + V+ M+VLK+A + +GD MLA
Sbjct 429 RPNTEGLGLDSLGVTLKRGGFIPVDACMRVLKHAPEGDEKPEVIRGVYCVGDANGQMMLA 488
Query 50 HKAEEEGIACVERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEE---QLKA-EGVSYKR 105
H A + +A VE +AG+ TV IP+ +T PE+A +G TEE +L A +G +
Sbjct 489 HAASAQAVAAVETIAGRPR-TVNVKHIPAACFTSPEIAFIGDTEEAAMELGAKDGFEVGK 547
Query 106 GAFPFAANSRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASE 165
F AN++A A G+ +G++KVL K+T KILG ++G +A +LI E A+ + +
Sbjct 548 SVSHFRANTKAIAEGEGEGILKVLYRKDTGKILGCHMIGIHASDLIQECATAITNDISVK 607
Query 166 DLGRVCHAHPTLSEALKEA 184
DL H HPTLSE + A
Sbjct 608 DLAFTVHTHPTLSEVVDAA 626
> pfa:PF08_0066 lipoamide dehydrogenase, putative (EC:1.8.1.4);
K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Length=666
Score = 95.1 bits (235), Expect = 1e-19, Method: Composition-based stats.
Identities = 72/229 (31%), Positives = 112/229 (48%), Gaps = 53/229 (23%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLK-----YAHIMAIGDLIEGPMLAHKAEEEG 56
P T++LGLE++ I ++ RG V VND +QV Y +I IGD MLAH A +
Sbjct 435 PNTQNLGLEKLKIQMN-RGYVSVNDNLQVKMENNEIYDNIFCIGDANGKQMLAHTASYQA 493
Query 57 IACVERLAGKGDGTVR------------HDTIPSVIYTHPELAGVGKTEEQLK------- 97
+ ++ + K V + IPSV YT+PELA +G TE++ K
Sbjct 494 LKVIDFIEKKEKKNVNINVENNLSKPILYKNIPSVCYTNPELAFIGLTEKEAKVLYPDNV 553
Query 98 AEGVSYKRGAFPFAANSRA----------------------RATGDSDGLVKVLTCKETD 135
+SY + +NS+ +++G+VK++ ++T
Sbjct 554 GVEISY------YKSNSKILCENNISLNNNKKNNSYNKGQYNINDNTNGMVKIIYKEDTK 607
Query 136 KILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEALKEA 184
+ILG++I+G A LI EAVLA+ ++ DL + H+HPT+SE L A
Sbjct 608 EILGMFIVGNYASVLIHEAVLAINLKLSAFDLAYMVHSHPTVSEVLDTA 656
> tgo:TGME49_019130 glutathione reductase, putative (EC:1.8.1.7)
Length=505
Score = 84.3 bits (207), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 58/187 (31%), Positives = 89/187 (47%), Gaps = 9/187 (4%)
Query 2 PYTRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
P DLGLEE G+D+D G + D Q I A+GD++ MLA A G
Sbjct 286 PAIEDLGLEEAGVDIDVNNGGFIKVDAFQNTSIPGIYAVGDVVGKAMLAPVAVAAGRLLA 345
Query 61 ERL-AGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKA----EGVSYKRGAF--PFAAN 113
+RL G+ + + +P+V+++HP L VG TEE K+ E ++ F F A
Sbjct 346 DRLFGGRSEARLDLSVVPTVVFSHPALGAVGMTEEDAKSLYGEENINVYTSTFIDSFYAA 405
Query 114 SRARATGDSDGLVKVLTCKE-TDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCH 172
+ VK++ K DK+LG+ ++G N E++ +A++ GA D
Sbjct 406 WSMPPSAKPKSFVKMVCLKTANDKVLGLHLVGRNVDEMLQGFAVAIKLGATKADFNSTLA 465
Query 173 AHPTLSE 179
HPT +E
Sbjct 466 IHPTAAE 472
> eco:b0304 ykgC, ECK0303, JW5040; predicted pyridine nucleotide-disulfide
oxidoreductase
Length=441
Score = 80.5 bits (197), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 92/184 (50%), Gaps = 2/184 (1%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
+P T L E GI +++RG +VV+ ++ +I A+GD+ G + + ++
Sbjct 253 QPATASLHPENAGIAVNERGAIVVDKRLHTTA-DNIWAMGDVTGGLQFTYISLDDYRIVR 311
Query 61 ERLAGKGD-GTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARAT 119
+ L G+G T +P ++ P L+ VG TEEQ + G + P AA RAR
Sbjct 312 DELLGEGKRSTDDRKNVPYSVFMTPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVM 371
Query 120 GDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSE 179
D+ G++K + +T ++LG +L ++ E+I + M+ G L HP++SE
Sbjct 372 NDTRGVLKAIVDNKTQRMLGASLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSE 431
Query 180 ALKE 183
+L +
Sbjct 432 SLND 435
> hsa:10587 TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2; thioredoxin
reductase 2 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH)
[EC:1.8.1.9]
Length=524
Score = 79.0 bits (193), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 59/189 (31%), Positives = 89/189 (47%), Gaps = 17/189 (8%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACV 60
P TR L LE+ G+D + ++ D + HI AIGD++EG P L A G V
Sbjct 320 PDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLV 379
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAE---------GVSYKRGAFPFA 111
+RL G + +D +P+ ++T E VG +EE+ A YK F A
Sbjct 380 QRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVA 439
Query 112 ANSRARATGDSDGLVKVLTCKETDK-ILGVWILGPNAGELIAEAVLAMEYGAASEDLGRV 170
++ VK++ +E + +LG+ LGPNAGE+ L ++ GA+ + R
Sbjct 440 GRDASQC------YVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRT 493
Query 171 CHAHPTLSE 179
HPT SE
Sbjct 494 VGIHPTCSE 502
> dre:100332932 glutathione reductase-like
Length=461
Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 85/183 (46%), Gaps = 7/183 (3%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P+TR LGLE G+ D G ++V D+ HI A+GD+ + L A E + +E
Sbjct 267 PHTRGLGLEAAGVATDAHGAIIV-DEYSRTSVPHIFALGDVTDRVQLTPVAIHEAMCFIE 325
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEE---QLKAEGVSYKRGAFPFAANSRARA 118
+ HD I + +++ PE+ VG +EE + AE Y+ P A R
Sbjct 326 TVYKDNPTKPDHDLIATAVFSQPEIGTVGLSEETAAERYAEIEVYRAEFRPMKATLSGR- 384
Query 119 TGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLS 178
L+K++ K++G ILG +AGE+ + ++ G ED R HPT +
Sbjct 385 --QEKMLMKLIVNAADRKVVGAHILGHDAGEMAQLLGITLKAGCTKEDFDRTMAVHPTAA 442
Query 179 EAL 181
E L
Sbjct 443 EEL 445
> mmu:26462 Txnrd2, AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2;
thioredoxin reductase 2 (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=527
Score = 76.3 bits (186), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 55/189 (29%), Positives = 90/189 (47%), Gaps = 17/189 (8%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACV 60
P TR L LE+ GI + + + ++ D + HI AIGD+ EG P L A + G
Sbjct 323 PETRTLNLEKAGISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLA 382
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ---------LKAEGVSYKRGAFPFA 111
+RL GK + + +P+ ++T E VG +EE+ ++ YK F A
Sbjct 383 QRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVA 442
Query 112 ANSRARATGDSDGLVKVLTCKETDK-ILGVWILGPNAGELIAEAVLAMEYGAASEDLGRV 170
++ +K++ +E + +LG+ LGPNAGE+ L ++ GA+ + +
Sbjct 443 DRDASQC------YIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQT 496
Query 171 CHAHPTLSE 179
HPT SE
Sbjct 497 VGIHPTCSE 505
> hsa:2936 GSR, MGC78522; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=522
Score = 75.5 bits (184), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 90/183 (49%), Gaps = 4/183 (2%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P T+DL L ++GI D +G ++V D+ Q I A+GD+ +L A G
Sbjct 337 PNTKDLSLNKLGIQTDDKGHIIV-DEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAH 395
Query 62 RLAG-KGDGTVRHDTIPSVIYTHPELAGVGKTE-EQLKAEGV-SYKRGAFPFAANSRARA 118
RL K D + ++ IP+V+++HP + VG TE E + G+ + K + F A
Sbjct 396 RLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVT 455
Query 119 TGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLS 178
+ ++K++ + +K++G+ + G E++ +A++ GA D HPT S
Sbjct 456 KRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSS 515
Query 179 EAL 181
E L
Sbjct 516 EEL 518
> mmu:14782 Gsr, AI325518, D8Ertd238e, Gr-1, Gr1; glutathione
reductase (EC:1.8.1.7); K00383 glutathione reductase (NADPH)
[EC:1.8.1.7]
Length=500
Score = 72.4 bits (176), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 50/183 (27%), Positives = 90/183 (49%), Gaps = 4/183 (2%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P ++ L L ++GI D++G ++V D+ Q + A+GD+ +L A G
Sbjct 315 PNSKGLNLNKVGIQTDEKGHILV-DEFQNTNVKGVYAVGDVCGKALLTPVAIAAGRKLAH 373
Query 62 RL-AGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQL--KAEGVSYKRGAFPFAANSRARA 118
RL K D + +D IP+V+++HP + VG TE++ K + K + F A
Sbjct 374 RLFECKQDSKLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKIYSTAFTPMYHAVT 433
Query 119 TGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLS 178
T + ++K++ + +K++G+ + G E++ +A++ GA D HPT S
Sbjct 434 TRKTKCVMKMVCANKEEKVVGIHMQGIGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSS 493
Query 179 EAL 181
E L
Sbjct 494 EEL 496
> mmu:50493 Txnrd1, TR, TR1, TrxR1; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=499
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 52/187 (27%), Positives = 91/187 (48%), Gaps = 13/187 (6%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACVE 61
TR +GLE +G+ ++ K G++ V D+ Q +I AIGD++EG + L A + G +
Sbjct 297 TRTIGLETVGVKINEKTGKIPVTDEEQT-NVPYIYAIGDILEGKLELTPVAIQAGRLLAQ 355
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ----LKAEGVS-YKRGAFPFAANSRA 116
RL G + +D +P+ ++T E G +EE+ E + Y +P +
Sbjct 356 RLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPS 415
Query 117 RATGDSDGLVKVLTC--KETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
R D++ + C K+ ++++G +LGPNAGE+ A++ G + L H
Sbjct 416 R---DNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIH 472
Query 175 PTLSEAL 181
P +E
Sbjct 473 PVCAEIF 479
> mmu:232223 Txnrd3, AI196535, TR2, Tgr; thioredoxin reductase
3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=652
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVE 61
TR +GLE++G+ ++ K G++ VND Q H+ AIGD+++G P L A + G
Sbjct 450 TRKIGLEKIGVKINEKNGKIPVNDVEQT-NVPHVYAIGDILDGKPELTPVAIQAGKLLAR 508
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ----LKAEGVS-YKRGAFPFAANSRA 116
RL G + IP+ ++T E G +EE+ K E + Y +P
Sbjct 509 RLFGVSLEKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAG 568
Query 117 RATGDSDGLVKVLTCKETD--KILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
R D++ + C + D +++G +LGPNAGE+ AM+ G + L H
Sbjct 569 R---DNNTCYAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIH 625
Query 175 PTLSEAL 181
PT E
Sbjct 626 PTCGEVF 632
> xla:447610 txnrd1, MGC85342; thioredoxin reductase 1 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=531
Score = 69.3 bits (168), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 56/189 (29%), Positives = 93/189 (49%), Gaps = 17/189 (8%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACVE 61
TR++GLE G+ ++ K G++ VND+ Q +I AIGD+I+ + L A + G +
Sbjct 331 TRNIGLEIPGVKINEKTGKIPVNDEEQT-NVPYIYAIGDVIQDKLELTPVAIQAGRLLAK 389
Query 62 RLAGKGDGTVRHD--TIPSVIYTHPELAGVGKTEE----QLKAEGVS-YKRGAFPFAANS 114
RL G D T++ D +P+ ++T E G +EE Q E V Y +P
Sbjct 390 RLYG--DSTLKSDYVNVPTTVFTPLEYGACGLSEENAIRQYGEENVEVYHSYFWPLEWTV 447
Query 115 RARATGDSDGLVKVLTC--KETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCH 172
AR D++ + C K+ ++++G +L PNAGE+ +A++ G + L
Sbjct 448 PAR---DNNKCYAKIICNLKDNERVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIG 504
Query 173 AHPTLSEAL 181
HP +E
Sbjct 505 IHPVCAEIF 513
> xla:447484 txnrd3, MGC81848; thioredoxin reductase 3 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=596
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 52/187 (27%), Positives = 91/187 (48%), Gaps = 13/187 (6%)
Query 4 TRDLGLEEMGIDLDKR-GRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACVE 61
TR++GLE++G+ +++R G++ V+D+ Q H+ AIGD+++G + L A + G
Sbjct 396 TRNIGLEKIGVKINERNGKIPVSDEEQT-SVPHVYAIGDILDGKLELTPVAIQAGRLLAR 454
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ----LKAEGVS-YKRGAFPFAANSRA 116
RL + +P+ ++T E G EE+ E + Y +P +
Sbjct 455 RLYRGSKVKCDYINVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTVPS 514
Query 117 RATGDSDGLVKVLTC--KETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
R D++ + C ++ D+++G +LGPNAGE+ AM+ G E L H
Sbjct 515 R---DNNTCFAKIICNKQDNDRVIGFHVLGPNAGEITQGFGAAMKCGLTKEKLDETIGIH 571
Query 175 PTLSEAL 181
PT +E
Sbjct 572 PTCAEIF 578
> ath:AT3G54660 GR; GR (GLUTATHIONE REDUCTASE); ATP binding /
glutathione-disulfide reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=565
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 51/185 (27%), Positives = 87/185 (47%), Gaps = 9/185 (4%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACV 60
+P T++LGLE +G+ + K G + V++ Q I A+GD+ + L A EG A
Sbjct 357 KPNTKNLGLENVGVKMAKNGAIEVDEYSQT-SVPSIWAVGDVTDRINLTPVALMEGGALA 415
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSR---AR 117
+ L + +P +++ P + VG TEEQ + + +N R A
Sbjct 416 KTLFQNEPTKPDYRAVPCAVFSQPPIGTVGLTEEQ----AIEQYGDVDVYTSNFRPLKAT 471
Query 118 ATGDSDG-LVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPT 176
+G D +K++ C T+K+LGV + G ++ E+I +A++ G D HPT
Sbjct 472 LSGLPDRVFMKLIVCANTNKVLGVHMCGEDSPEIIQGFGVAVKAGLTKADFDATVGVHPT 531
Query 177 LSEAL 181
+E
Sbjct 532 AAEEF 536
> cel:ZK637.10 trxr-2; ThioRedoXin Reductase family member (trxr-2);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=503
Score = 65.9 bits (159), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 80/186 (43%), Gaps = 6/186 (3%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACV 60
P + L L+ G+ DKR ++ D+ + A+GD+++ L A + G
Sbjct 298 PNLKSLNLDNAGVRTDKRSGKILADEFDRASCNGVYAVGDIVQDRQELTPLAIQSGKLLA 357
Query 61 ERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ-LKAEGVS----YKRGAFPFAANSR 115
+RL VR D + + ++T EL+ VG TEE+ ++ G + PF
Sbjct 358 DRLFSNSKQIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTPFEYVVP 417
Query 116 ARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHP 175
+ V T E+ KILG+ +GPNA E+I +A G + DL HP
Sbjct 418 QNKDSGFCYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHP 477
Query 176 TLSEAL 181
SE
Sbjct 478 CSSEEF 483
> cel:C06G3.7 trxr-1; ThioRedoXin Reductase family member (trxr-1);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=667
Score = 65.9 bits (159), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 7/184 (3%)
Query 4 TRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVER 62
T D+GL +G++ K +V+ + Q + AIGD++EG P L A + G + R
Sbjct 464 TDDVGLTTIGVERAKSKKVL-GRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRR 522
Query 63 LAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQL-----KAEGVSYKRGAFPFAANSRAR 117
+ + +D IP+ ++T E G +EE K + Y P R
Sbjct 523 IFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISER 582
Query 118 ATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTL 177
D L + E +K++G IL PNAGE+ +A++ A D R+ HPT+
Sbjct 583 MDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTV 642
Query 178 SEAL 181
+E
Sbjct 643 AENF 646
> xla:379744 txnrd2, MGC69182; thioredoxin reductase 2 (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=504
Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 85/187 (45%), Gaps = 17/187 (9%)
Query 4 TRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVER 62
T+ L LE++G+ + ++ D + HI AIGD+ EG P L A G R
Sbjct 302 TQYLNLEKVGVKIKPETGKIIVDASEATSVPHIYAIGDITEGRPELTPTAIAAGKLLAIR 361
Query 63 LAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAE---------GVSYKRGAFPFAAN 113
L + +D++P+ ++T E VG +EE+ K YK F A
Sbjct 362 LFSGSAELMDYDSVPTTVFTPLEYGCVGISEEEAKERYGDDNIEVFHAFYKPLEFTVAER 421
Query 114 SRARATGDSDGLVKVLTCKETD-KILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCH 172
++ +K++ ++ D +ILG+ + GPNAGE+I L ++ GA L
Sbjct 422 DASQC------YIKIICLRKHDQRILGLHLTGPNAGEVIQGFALGIKCGATYPQLMCTVG 475
Query 173 AHPTLSE 179
HPT +E
Sbjct 476 IHPTCAE 482
> bbo:BBOV_I002190 19.m02214; thiodoxin reductase (EC:1.8.1.9);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=559
Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 53/188 (28%), Positives = 89/188 (47%), Gaps = 17/188 (9%)
Query 9 LEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVERLAGKG 67
L ++GI K G + ++ M Y ++ A+GD+ EG P LA A ++G RL G
Sbjct 349 LSDLGIKFSKSGLIETDNGMT--GYPNVYAVGDVAEGNPALATVAVKDGEMLARRLFGNS 406
Query 68 DGTVRHDTIPSVIYTHPELAGVGKTEEQ-LKAEG---VSYKR-GAFPFAANSRARA---- 118
+ + + +P ++T E G +EE+ +K G + K + F+A R +
Sbjct 407 NKLMDLNYVPMCVFTPIEYGKCGLSEEEAVKKYGDVDIYLKEFTSLEFSAVHRHKVEWMQ 466
Query 119 TGDSD-----GLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHA 173
T + D + + CK+ I+G+ +GPNAGE+I +A+ GA D
Sbjct 467 TDEMDVDMPPTCLSKMICKKDGTIVGIHFVGPNAGEIIQGLCVAVRLGAKKSDFDDTIGV 526
Query 174 HPTLSEAL 181
HPT +E+
Sbjct 527 HPTDAESF 534
> tgo:TGME49_109730 thioredoxin reductase, putative (EC:1.8.1.7);
K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=662
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 20/197 (10%)
Query 4 TRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVER 62
T +L L+ G++ + G++V + + AIGD +E P L A + G R
Sbjct 442 TSNLNLQAAGVETTETGKIVCDGDSHT-SAPSVYAIGDAVENFPELTPVAIKAGEILARR 500
Query 63 LAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEG-------VSYKRGAFPFAANSR 115
L + IP+ ++T E A G +EE +AE ++ F+ R
Sbjct 501 LFANSTEHMDFTNIPTTVFTPIEYAHTGYSEEAAEAEFGRDDLEVYLFQFSPLFFSCVHR 560
Query 116 ARATG------DSD----GLVKVLTCK-ETDKILGVWILGPNAGELIAEAVLAMEYGAAS 164
+A D D L K++ K E +K++G+ +GPNAGEL+ LA+ GA
Sbjct 561 EKAPQARKSPEDVDITPPCLAKLICVKSEDEKVVGIHFVGPNAGELMQGFALAVRLGAKK 620
Query 165 EDLGRVCHAHPTLSEAL 181
D + HPT +EA
Sbjct 621 RDFDKCVGIHPTNAEAF 637
> eco:b3500 gor, ECK3485, gorA, JW3467; glutathione oxidoreductase
(EC:1.8.1.7); K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=450
Score = 64.3 bits (155), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 4/183 (2%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P ++ LE G+ +++G +VV DK Q I A+GD L A G E
Sbjct 265 PANDNINLEAAGVKTNEKGYIVV-DKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSE 323
Query 62 RL-AGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAF--PFAANSRARA 118
RL K D + + IP+V+++HP + VG TE Q + + + + F A A
Sbjct 324 RLFNNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVT 383
Query 119 TGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLS 178
T +K++ +KI+G+ +G E++ +A++ GA +D HPT +
Sbjct 384 THRQPCRMKLVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAA 443
Query 179 EAL 181
E
Sbjct 444 EEF 446
> hsa:7296 TXNRD1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=649
Score = 63.9 bits (154), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 49/187 (26%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACVE 61
TR +GLE +G+ ++ K G++ V D+ Q +I AIGD++E + L A + G +
Sbjct 447 TRKIGLETVGVKINEKTGKIPVTDEEQT-NVPYIYAIGDILEDKVELTPVAIQAGRLLAQ 505
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ----LKAEGVS-YKRGAFPFAANSRA 116
RL ++ +P+ ++T E G +EE+ E + Y +P +
Sbjct 506 RLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPS 565
Query 117 RATGDSDGLVKVLTC--KETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
R D++ + C K+ ++++G +LGPNAGE+ A++ G + L H
Sbjct 566 R---DNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIH 622
Query 175 PTLSEAL 181
P +E
Sbjct 623 PVCAEVF 629
> dre:352924 txnrd1, TrxR1, cb682, fb83a08, wu:fb83a08; thioredoxin
reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=602
Score = 63.2 bits (152), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 84/187 (44%), Gaps = 13/187 (6%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIEGPM-LAHKAEEEGIACVE 61
T +GL++ G+ ++ K G+V VND+ Q HI AIGD++EG L A + G
Sbjct 400 TGKIGLDKAGVKINEKNGKVPVNDEEQT-NVPHIYAIGDILEGKWELTPVAIQAGKLLAR 458
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQ-LKAEGVS----YKRGAFPFAANSRA 116
RL + +P+ ++T E G EE+ ++ G Y +P
Sbjct 459 RLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPG 518
Query 117 RATGDSDGLVKVLTCKETD--KILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
R D++ + C + D +++G LGPNAGE+ AM+ G + L H
Sbjct 519 R---DNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIH 575
Query 175 PTLSEAL 181
PT +E
Sbjct 576 PTCAEIF 582
> tgo:TGME49_046920 glutathione reductase, putative (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 63.2 bits (152), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 54/189 (28%), Positives = 89/189 (47%), Gaps = 19/189 (10%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P +LGL+ +G+ + G +V D+ Q I A+GD+ L A G +
Sbjct 288 PEVANLGLDVVGVK-QRHGGYIVADEFQNTSVEQIYAVGDVSGKIELTPVAIAAGRRLAD 346
Query 62 RLAGKGDGTVRHDT--IPSVIYTHPELAGVGKTEEQLKAE--------GVSYKRGAFPFA 111
RL G G + D+ +P+V+++HP A VG TE + KA V+ GA+P A
Sbjct 347 RLFG-GLCNAKLDSACVPTVVFSHPPAACVGLTEAEAKATYGEKDIKVHVNLYYGAWPVA 405
Query 112 ANSRARATGDSDGLVKVLTCK-ETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRV 170
+ + +K++ K + K++G+ ++G A E+I +AM+ GA D
Sbjct 406 PEEKPKT------FIKMICVKSQMLKVVGLHVVGMGADEMIQGFGVAMKMGATKADFDNC 459
Query 171 CHAHPTLSE 179
HPT +E
Sbjct 460 VAVHPTAAE 468
> cpv:cgd2_4320 thioredoxin reductase 1 ; K00384 thioredoxin reductase
(NADPH) [EC:1.8.1.9]
Length=526
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 52/201 (25%), Positives = 88/201 (43%), Gaps = 23/201 (11%)
Query 1 RPYTRDLGLEEMGIDLDKRGRVVV-NDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIA 58
P + L L +G+++ G+++ D V I A+GD++EG P L A + GI
Sbjct 304 NPDVKGLNLNAIGVEVSDSGKIIAPKDATSV---PSIFAVGDIVEGRPELTPVAVKAGIL 360
Query 59 CVERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKA-------EGVSYKRGAFPFA 111
RL + + +D +P+ ++T E VG + E A E + A
Sbjct 361 LARRLFAGSNEFIDYDFVPTTVFTPIEYGHVGLSSEAAIAKYGEDDIEEYLSEFSTLEIA 420
Query 112 ANSRARATGDSDG----------LVKVLTCK-ETDKILGVWILGPNAGELIAEAVLAMEY 160
A R + + L K++ K + +K++G +GPNAGE+ LA++
Sbjct 421 AAHREKPEHLRENEMDFALPLNCLAKLVVVKSQGEKVVGFHFVGPNAGEITQGFSLAVKL 480
Query 161 GAASEDLGRVCHAHPTLSEAL 181
GA +D + HPT +E
Sbjct 481 GATKKDFDDMIGIHPTDAEVF 501
> tpv:TP03_0110 thioredoxin reductase (EC:1.6.4.5); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=567
Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 15/187 (8%)
Query 8 GLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVERLAGK 66
L E+G++ D G ++ ++ +K ++ A+GD++ P LA A + ++RL
Sbjct 358 NLRELGLEFDGNGNIIAPNEETNIK--NVYAVGDIVSKVPKLAPVAIKSSELLIQRLYSN 415
Query 67 GDGTVRHDTIPSVIYTHPELAGVGKTEEQ---------LKAEGVSYKRGAFPFAANSRAR 117
+ + ++ +P +YT E + G TEE+ L+ Y +
Sbjct 416 TNTKMNYENVPKCVYTPFEYSSCGLTEEEAIERFGEENLEIYLKEYNNLEISPVHRINKK 475
Query 118 ATGDSDGLVKVLT---CKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAH 174
+ D + L+ C KI+G+ +GPNAGE++ + A DL + H
Sbjct 476 TNDEFDYPMTCLSKVICLRDGKIVGMHFVGPNAGEIMQGFSVLFTLNAKKSDLDKTVGIH 535
Query 175 PTLSEAL 181
PT +E+
Sbjct 536 PTDAESF 542
> sce:YPL091W GLR1, LPG17; Cytosolic and mitochondrial glutathione
oxidoreductase, converts oxidized glutathione to reduced
glutathione; mitochondrial but not cytosolic form has a role
in resistance to hyperoxia (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=483
Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 85/182 (46%), Gaps = 10/182 (5%)
Query 7 LGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVERLAGK 66
+G E +GI L+ +++ D+ Q +I ++GD++ L A G RL G
Sbjct 301 MGSENVGIKLNSHDQIIA-DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGP 359
Query 67 ---GDGTVRHDTIPSVIYTHPELAGVGKTE----EQLKAEGVSYKRGAFPFAANSRARAT 119
+ + ++ +PSVI++HPE +G +E E+ E + F A A +
Sbjct 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKF--TAMYYAMLS 417
Query 120 GDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSE 179
S K++ +K++G+ I+G ++ E++ +A++ GA D HPT +E
Sbjct 418 EKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477
Query 180 AL 181
L
Sbjct 478 EL 479
> xla:734372 gsr, MGC84926; glutathione reductase (EC:1.8.1.7);
K00383 glutathione reductase (NADPH) [EC:1.8.1.7]
Length=476
Score = 60.1 bits (144), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 45/168 (26%), Positives = 84/168 (50%), Gaps = 4/168 (2%)
Query 17 DKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVERL-AGKGDGTVRHDT 75
D++G +VV D+ Q + A+GD+ +L A G RL G+ D + ++
Sbjct 306 DEKGHIVV-DEFQNTSRKGVYAVGDVCGRALLTPVAIAAGRKLSHRLFEGQEDSKLDYNN 364
Query 76 IPSVIYTHPELAGVGKTEEQ-LKAEGV-SYKRGAFPFAANSRARATGDSDGLVKVLTCKE 133
IP+V+++HP + VG TEE+ + A+G + K F+ + ++K++ +
Sbjct 365 IPTVVFSHPPIGTVGLTEEEAVTAKGRENVKVYTTSFSPMYHVVTRRKTKCVMKLVCVGK 424
Query 134 TDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEAL 181
+K++G+ + G E++ +A++ GA +D HPT SE L
Sbjct 425 EEKVVGLHMQGLGCDEMLQGFAVAIKMGATKKDFDNTVAIHPTSSEEL 472
> pfa:PFI1170c thioredoxin reductase (EC:1.8.1.9); K00384 thioredoxin
reductase (NADPH) [EC:1.8.1.9]
Length=617
Score = 59.7 bits (143), Expect = 5e-09, Method: Composition-based stats.
Identities = 51/194 (26%), Positives = 79/194 (40%), Gaps = 19/194 (9%)
Query 7 LGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEG-PMLAHKAEEEGIACVERLAG 65
L LE + ++++K ++ D + I A+GD+ E P LA A + G RL
Sbjct 399 LNLESLNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFK 458
Query 66 KGDGTVRHDTIPSVIYTHPELAGVGKTEEQL-------KAEGVSYKRGAFPFAANSRA-- 116
D + + IP+ IYT E G +EE+ E + +A R
Sbjct 459 DSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKH 518
Query 117 -RATGDSDGLVKVLTC--------KETDKILGVWILGPNAGELIAEAVLAMEYGAASEDL 167
RA D L TC E ++++G +GPNAGE+ LA+ +D
Sbjct 519 IRAQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDF 578
Query 168 GRVCHAHPTLSEAL 181
HPT +E+
Sbjct 579 DNCIGIHPTDAESF 592
> ath:AT3G24170 ATGR1; ATGR1 (glutathione-disulfide reductase);
FAD binding / NADP or NADPH binding / glutathione-disulfide
reductase/ oxidoreductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=499
Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 78/182 (42%), Gaps = 8/182 (4%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P T+ L LE +G++LD+ G V V D+ I A+GD L A E
Sbjct 300 PNTKRLNLEAVGVELDQAGAVKV-DEYSRTNIPSIWAVGDATNRINLTPVALMEATCFAN 358
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEE----QLKAEGVSYKRGAFPFAANSRAR 117
G + + ++ P LA VG +EE Q + + + G P R
Sbjct 359 TAFGGKPTKAEYSNVACAVFCIPPLAVVGLSEEEAVEQATGDILVFTSGFNPMKNTISGR 418
Query 118 ATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTL 177
L+K++ +++DK++G + GP+A E++ +A++ GA HP+
Sbjct 419 ---QEKTLMKLIVDEKSDKVIGASMCGPDAAEIMQGIAIALKCGATKAQFDSTVGIHPSS 475
Query 178 SE 179
+E
Sbjct 476 AE 477
> cel:C46F11.2 hypothetical protein
Length=473
Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 14/188 (7%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P T++L LE +G+ DK G ++V D+ Q I+++GD +L A G
Sbjct 282 PLTKELNLERVGVKTDKSGHIIV-DEYQNTSAPGILSVGDDTGKFLLTPVAIAAGRRLSH 340
Query 62 RL-AGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQL-----KAEGVSYKRGAFP--FAAN 113
RL G+ D + ++ I +V+++HP + VG TE + K E YK P FA
Sbjct 341 RLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVT 400
Query 114 SRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHA 173
+K++ + +K++GV + G + E++ +A+ GA + +
Sbjct 401 KHKEKAA-----MKLVCVGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAI 455
Query 174 HPTLSEAL 181
HPT +E L
Sbjct 456 HPTSAEEL 463
> hsa:114112 TXNRD3, TGR, TR2, TRXR3; thioredoxin reductase 3
(EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9]
Length=607
Score = 50.8 bits (120), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 35/180 (19%)
Query 4 TRDLGLEEMGIDLD-KRGRVVVNDKMQVLKYAHIMAIGDLIE-GPMLAHKAEEEGIACVE 61
TR +GLE++G+ ++ K G++ VND Q ++ A+GD++E P L A + G +
Sbjct 441 TRKIGLEKIGVKINEKSGKIPVNDVEQT-NVPYVYAVGDILEDKPELTPVAIQSGKLLAQ 499
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATGD 121
RL G + H ++ E G+ A+ + K
Sbjct 500 RLFGASLEKIYH-----TLFWPLEWTVAGRENNTCYAKIICNKF---------------- 538
Query 122 SDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEAL 181
+ D+++G ILGPNAGE+ AM+ G + L HPT E
Sbjct 539 -----------DHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVF 587
> pfa:PF14_0192 glutathione reductase (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=500
Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 6/147 (4%)
Query 41 DLIEGPMLAHKAEEEGIACVERLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEE---QLK 97
D+ L A G +RL K + IP+VI++HP + +G +EE Q+
Sbjct 346 DIFYNVQLTPVAINAGRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIY 405
Query 98 -AEGVSYKRGAFP--FAANSRARATGDSDGLVKVLTCKETDKILGVWILGPNAGELIAEA 154
E V F F + +K++ + + I G+ I+G NA E++
Sbjct 406 GKENVKIYESKFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGF 465
Query 155 VLAMEYGAASEDLGRVCHAHPTLSEAL 181
+A++ A +D HPT +E
Sbjct 466 AVALKMNATKKDFDETIPIHPTAAEEF 492
> dre:553575 MGC110010; zgc:110010 (EC:1.8.1.7); K00383 glutathione
reductase (NADPH) [EC:1.8.1.7]
Length=425
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 42/180 (23%)
Query 2 PYTRDLGLEEMGIDLDKRGRVVVNDKMQVLKYAHIMAIGDLIEGPMLAHKAEEEGIACVE 61
P T L L ++G+ LD+RG +VV D+ Q + A+GD+ +L
Sbjct 284 PNTAGLNLSQIGVKLDERGHIVV-DEFQNTSRPGVYAVGDVCGRALLT------------ 330
Query 62 RLAGKGDGTVRHDTIPSVIYTHPELAGVGKTEEQLKAEGVSYKRGAFPFAANSRARATGD 121
P+ A ++++K S+ +A SR
Sbjct 331 ----------------------PDEAVKTYGKDKVKVYTTSFT--PMYYAITSRK----- 361
Query 122 SDGLVKVLTCKETDKILGVWILGPNAGELIAEAVLAMEYGAASEDLGRVCHAHPTLSEAL 181
S ++K++ E +K++G+ + G E++ +A+ GA D R HPT SE L
Sbjct 362 SQCIMKLVCAGENEKVVGLHMQGFGCDEMLQGFAVAVNMGATKADFDRTIAIHPTSSEEL 421
Lambda K H
0.318 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 5429324208
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40