bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
164,496 sequences; 82,071,388 total letters
Query= Emax_2927_orf1
Length=122
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_039490 mitochondrial branched-chain alpha-keto acid... 182 1e-46
bbo:BBOV_III008200 17.m07717; dehydrogenase E1 component famil... 156 2e-38
tpv:TP04_0719 branched-chain alpha keto-acid dehydrogenase (EC... 154 7e-38
pfa:PF13_0070 branched-chain alpha keto-acid dehydrogenase, pu... 138 5e-33
mmu:12039 Bckdha; branched chain ketoacid dehydrogenase E1, al... 137 1e-32
hsa:593 BCKDHA, BCKDE1A, FLJ45695, MSU, MSUD1, OVD1A; branched... 134 6e-32
cel:Y39E4A.3 hypothetical protein; K00166 2-oxoisovalerate deh... 130 7e-31
dre:554124 bckdha, wu:fd20d04, zgc:110049; branched chain keto... 130 1e-30
ath:AT1G21400 2-oxoisovalerate dehydrogenase, putative / 3-met... 123 1e-28
ath:AT5G09300 2-oxoisovalerate dehydrogenase, putative / 3-met... 123 2e-28
tgo:TGME49_092100 2-oxoisovalerate dehydrogenase, putative (EC... 119 2e-27
ath:AT5G34780 dehydrogenase E1 component family protein; K0016... 116 2e-26
sce:YER178W PDA1; E1 alpha subunit of the pyruvate dehydrogena... 62.4 4e-10
ath:AT1G59900 AT-E1 ALPHA; oxidoreductase, acting on the aldeh... 52.8 3e-07
ath:AT1G24180 IAR4; IAR4; oxidoreductase, acting on the aldehy... 52.0 5e-07
mmu:18597 Pdha1, Pdha-1; pyruvate dehydrogenase E1 alpha 1 (EC... 48.5 4e-06
dre:406702 pdha1a, im:6895726, pdha1, wu:fd18b01, wu:fo96f03, ... 48.5 5e-06
cel:T05H10.6 hypothetical protein; K00161 pyruvate dehydrogena... 48.1 6e-06
hsa:5160 PDHA1, PDHA, PDHCE1A, PHE1A; pyruvate dehydrogenase (... 47.8 1e-05
xla:446473 pdha1-a, MGC79036, pdha, pdha1, pdhce1a, phe1a; pyr... 47.4 1e-05
pfa:PF11_0256 pyruvate dehydrogenase E1 component, alpha subun... 47.0 1e-05
hsa:5161 PDHA2, MGC149517, MGC149518, PDHAL; pyruvate dehydrog... 46.2 3e-05
xla:447434 pdha1-b, MGC132282, MGC80338, pdha, pdhce1a, phe1a;... 45.4 4e-05
dre:436672 pdha1b, Pdha1, wu:fp73b04, zgc:92705; pyruvate dehy... 45.1 6e-05
mmu:18598 Pdha2, Pdhal; pyruvate dehydrogenase E1 alpha 2 (EC:... 41.2 8e-04
tgo:TGME49_045670 pyruvate dehydrogenase, putative (EC:1.2.4.1) 39.3 0.003
ath:AT1G01090 PDH-E1 ALPHA (PYRUVATE DEHYDROGENASE E1 ALPHA); ... 37.4 0.010
ath:AT1G02980 CUL2; CUL2 (CULLIN 2); ubiquitin protein ligase ... 30.0 1.7
dre:566491 bcl11ab, si:ch211-127m10.2; B-cell CLL/lymphoma 11Ab 28.5 5.5
pfa:PF08_0138 RIF; rifin; K13851 repetitive interspersed famil... 28.1 6.7
cel:C07A9.6 ugt-60; UDP-GlucuronosylTransferase family member ... 28.1 7.6
> tgo:TGME49_039490 mitochondrial branched-chain alpha-keto acid
dehydrogenase E1, putative (EC:1.2.4.4); K00166 2-oxoisovalerate
dehydrogenase E1 component, alpha subunit [EC:1.2.4.4]
Length=463
Score = 182 bits (463), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 84/122 (68%), Positives = 102/122 (83%), Gaps = 0/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
V+DQYAGDGIAIRGISYG+ TIR+DGNDLFAS LATK+AR++I+ +PVL+EFMTYRVG
Sbjct 289 VKDQYAGDGIAIRGISYGMHTIRVDGNDLFASLLATKKAREIIVSQRQPVLIEFMTYRVG 348
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSDDS YRP GELEAW SGI PIAR+R+YL + W+D+++EELRK++R ML
Sbjct 349 HHSTSDDSFQYRPSGELEAWGQSGIHPIARVRRYLDNLNLWSDKQDEELRKDARATMLRM 408
Query 121 MK 122
MK
Sbjct 409 MK 410
> bbo:BBOV_III008200 17.m07717; dehydrogenase E1 component family
protein (EC:1.2.4.1); K00166 2-oxoisovalerate dehydrogenase
E1 component, alpha subunit [EC:1.2.4.4]
Length=447
Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 68/122 (55%), Positives = 95/122 (77%), Gaps = 0/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
VRDQY GDGIAIRG++YG+ +IR+DGNDLFAS++ATK AR+ + + P+ +E+MTYR+G
Sbjct 274 VRDQYRGDGIAIRGVAYGMPSIRVDGNDLFASYIATKHAREHCIKHSTPICIEYMTYRLG 333
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSD+SS YR GE + W + GI I R++ YL G W +E +EEL+KE+RKYML++
Sbjct 334 HHSTSDESSQYRGAGEFDVWTSGGINAINRVKTYLEKRGIWDNERDEELQKEARKYMLKK 393
Query 121 MK 122
++
Sbjct 394 IR 395
> tpv:TP04_0719 branched-chain alpha keto-acid dehydrogenase (EC:1.2.4.4);
K00166 2-oxoisovalerate dehydrogenase E1 component,
alpha subunit [EC:1.2.4.4]
Length=464
Score = 154 bits (389), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 69/122 (56%), Positives = 91/122 (74%), Gaps = 0/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
VRDQY GDGIAIRG++ GI +IR+DGNDLFAS++ATK R+ + + P+++E+MTYR+G
Sbjct 289 VRDQYIGDGIAIRGVALGIPSIRVDGNDLFASYMATKYCREYCVKHSTPIVIEYMTYRIG 348
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSD+SS YR GE EAW G+ PI RL YL +G W+ EEE LRK + YML++
Sbjct 349 HHSTSDESSQYRGKGEFEAWAMDGVNPIKRLGLYLESKGLWSKEEEAALRKSATSYMLKK 408
Query 121 MK 122
+K
Sbjct 409 IK 410
> pfa:PF13_0070 branched-chain alpha keto-acid dehydrogenase,
putative (EC:1.2.4.2); K00166 2-oxoisovalerate dehydrogenase
E1 component, alpha subunit [EC:1.2.4.4]
Length=429
Score = 138 bits (347), Expect = 5e-33, Method: Composition-based stats.
Identities = 61/122 (50%), Positives = 93/122 (76%), Gaps = 0/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
++DQY GDGIA R ++ GI++IR+DGNDLFAS+LATK+ R + + ++PV +EFM+YR G
Sbjct 257 IKDQYRGDGIAPRALALGIESIRVDGNDLFASYLATKKLRDICIQESKPVFIEFMSYRYG 316
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSDDSS YRP E EAW G+ PI+R+ YL ++ ++++E++E RK ++ +L++
Sbjct 317 HHSTSDDSSLYRPKEENEAWRQEGVHPISRIFLYLKNKNLYSEKEDQEHRKSVKENVLKE 376
Query 121 MK 122
+K
Sbjct 377 LK 378
> mmu:12039 Bckdha; branched chain ketoacid dehydrogenase E1,
alpha polypeptide (EC:1.2.4.4); K00166 2-oxoisovalerate dehydrogenase
E1 component, alpha subunit [EC:1.2.4.4]
Length=446
Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 65/117 (55%), Positives = 88/117 (75%), Gaps = 1/117 (0%)
Query 3 DQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQH 62
+QY GDGIA RG YGI +IR+DGND+FA + ATK+AR+ + N+P L+E MTYR+G H
Sbjct 278 EQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHH 337
Query 63 STSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLE 119
STSDDSSAYR E+ W+ PI+RLR+YL ++GWW +E+E+ RK+SRK ++E
Sbjct 338 STSDDSSAYRSVDEVNYWDKQD-HPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVME 393
> hsa:593 BCKDHA, BCKDE1A, FLJ45695, MSU, MSUD1, OVD1A; branched
chain keto acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4);
K00166 2-oxoisovalerate dehydrogenase E1 component,
alpha subunit [EC:1.2.4.4]
Length=445
Score = 134 bits (338), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 64/117 (54%), Positives = 86/117 (73%), Gaps = 1/117 (0%)
Query 3 DQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQH 62
+QY GDGIA RG YGI +IR+DGND+FA + ATK+AR+ + N+P L+E MTYR+G H
Sbjct 277 EQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHH 336
Query 63 STSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLE 119
STSDDSSAYR E+ W+ PI+RLR YL +GWW +E+E+ RK+SR+ ++E
Sbjct 337 STSDDSSAYRSVDEVNYWDKQD-HPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVME 392
> cel:Y39E4A.3 hypothetical protein; K00166 2-oxoisovalerate dehydrogenase
E1 component, alpha subunit [EC:1.2.4.4]
Length=432
Score = 130 bits (328), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 63/119 (52%), Positives = 85/119 (71%), Gaps = 2/119 (1%)
Query 3 DQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQH 62
+QY GDGIA +G +YG+ TIR+DGNDL A + ATK+AR++ L TN PVL+E MTYR+G H
Sbjct 262 EQYGGDGIAGKGPAYGLHTIRVDGNDLLAVYNATKEARRVAL-TNRPVLIEAMTYRLGHH 320
Query 63 STSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQM 121
STSDDS+AYR E++ W PI R +KY+ GWW +E+E E +KE +K +L +
Sbjct 321 STSDDSTAYRSSDEVQTWGDKD-HPITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEF 378
> dre:554124 bckdha, wu:fd20d04, zgc:110049; branched chain keto
acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4); K00166
2-oxoisovalerate dehydrogenase E1 component, alpha subunit
[EC:1.2.4.4]
Length=446
Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 62/117 (52%), Positives = 83/117 (70%), Gaps = 1/117 (0%)
Query 3 DQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQH 62
+QY GDGIA RG YG+ +IR+DGND+FA + ATK+AR+ + N+P L+E MTYR+G H
Sbjct 278 EQYRGDGIAARGPGYGLMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHH 337
Query 63 STSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLE 119
STSDDSSAYR E+ W+ PI+RLR Y+ WW ++EE RK+SRK ++E
Sbjct 338 STSDDSSAYRSVDEVNYWDKQD-HPISRLRHYMTARDWWGEDEERAWRKQSRKLVME 393
> ath:AT1G21400 2-oxoisovalerate dehydrogenase, putative / 3-methyl-2-oxobutanoate
dehydrogenase, putative / branched-chain
alpha-keto acid dehydrogenase E1 alpha subunit, putative;
K00166 2-oxoisovalerate dehydrogenase E1 component, alpha subunit
[EC:1.2.4.4]
Length=472
Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 54/122 (44%), Positives = 84/122 (68%), Gaps = 1/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
+ +Q+ DGI ++G +YGI++IR+DGND A + A + AR++ + PVL+E MTYRVG
Sbjct 303 ISEQFRSDGIVVKGQAYGIRSIRVDGNDALAVYSAVRSAREMAVTEQRPVLIEMMTYRVG 362
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSDDS+ YR E++ W S P+ R RK++ GWW++E+E +LR +RK +L+
Sbjct 363 HHSTSDDSTKYRAADEIQYWKMSRN-PVNRFRKWVEDNGWWSEEDESKLRSNARKQLLQA 421
Query 121 MK 122
++
Sbjct 422 IQ 423
> ath:AT5G09300 2-oxoisovalerate dehydrogenase, putative / 3-methyl-2-oxobutanoate
dehydrogenase, putative / branched-chain
alpha-keto acid dehydrogenase E1 alpha subunit, putative;
K00166 2-oxoisovalerate dehydrogenase E1 component, alpha subunit
[EC:1.2.4.4]
Length=472
Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 54/120 (45%), Positives = 82/120 (68%), Gaps = 1/120 (0%)
Query 3 DQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQH 62
DQ+ DG+ ++G +YGI++IR+DGND A + A AR++ + P+L+E +TYRVG H
Sbjct 305 DQFRSDGVVVKGRAYGIRSIRVDGNDALAMYSAVHTAREMAIREQRPILIEALTYRVGHH 364
Query 63 STSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQMK 122
STSDDS+ YR GE+E WN + P++R R ++ GWW+D+ E +LR +K MLE ++
Sbjct 365 STSDDSTRYRSAGEIEWWNKARN-PLSRFRTWIESNGWWSDKTESDLRSRIKKEMLEALR 423
> tgo:TGME49_092100 2-oxoisovalerate dehydrogenase, putative (EC:1.2.4.4);
K00166 2-oxoisovalerate dehydrogenase E1 component,
alpha subunit [EC:1.2.4.4]
Length=516
Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats.
Identities = 57/122 (46%), Positives = 81/122 (66%), Gaps = 0/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
V +QY GDG+ R ++YGI T+R+DG DL A + A K AR+L++ +P +E MTYR+G
Sbjct 335 VGEQYKGDGVGARAVAYGIDTVRVDGTDLVAVYAAVKAARELVVAQRKPAFVEMMTYRIG 394
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSD+S AYR E+E W AS PI R +L ++G W+ EEE L E+RK +L +
Sbjct 395 HHSTSDESGAYRSAEEVEQWQASAAHPIRRFATFLTNQGRWSAEEESALVVETRKEVLAK 454
Query 121 MK 122
++
Sbjct 455 IR 456
> ath:AT5G34780 dehydrogenase E1 component family protein; K00166
2-oxoisovalerate dehydrogenase E1 component, alpha subunit
[EC:1.2.4.4]
Length=365
Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 52/122 (42%), Positives = 80/122 (65%), Gaps = 1/122 (0%)
Query 1 VRDQYAGDGIAIRGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVG 60
+ +Q+ DGI ++G +YGI++IR+DGND A + A AR++ + PVL+E M YRVG
Sbjct 73 ISEQFRSDGIVVKGQAYGIRSIRVDGNDALAVYSAVCSAREMAVTEQRPVLIEMMIYRVG 132
Query 61 QHSTSDDSSAYRPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
HSTSDDS+ YR E++ W S + R RK + GWW++E+E +LR +RK +L+
Sbjct 133 HHSTSDDSTKYRAADEIQYWKMSRN-SVNRFRKSVEDNGWWSEEDESKLRSNARKQLLQA 191
Query 121 MK 122
++
Sbjct 192 IQ 193
> sce:YER178W PDA1; E1 alpha subunit of the pyruvate dehydrogenase
(PDH) complex, catalyzes the direct oxidative decarboxylation
of pyruvate to acetyl-CoA; phosphorylated; regulated
by glucose (EC:1.2.4.1); K00161 pyruvate dehydrogenase E1 component
subunit alpha [EC:1.2.4.1]
Length=420
Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 35/104 (33%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I ++++G D+ A + A+K A+ L P+++E+ TYR G HS SD + YR E++
Sbjct 269 IPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQ 328
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQMK 122
+ PIA L+ +L G T+ E + K +RKY+ EQ++
Sbjct 329 HMRSKND-PIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVE 371
> ath:AT1G59900 AT-E1 ALPHA; oxidoreductase, acting on the aldehyde
or oxo group of donors, disulfide as acceptor / pyruvate
dehydrogenase (acetyl-transferring) (EC:1.2.4.1); K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=389
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 10/101 (9%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
+ +++DG D FA A K A+Q L+ P+++E TYR HS SD S YR E+
Sbjct 249 VPGLKVDGMDAFAVKQACKFAKQHALEKG-PIILEMDTYRYHGHSMSDPGSTYRTRDEI- 306
Query 79 AWNASGIL----PIARLRKYLAHEGWWTDEEEEELRKESRK 115
SG+ PI R++K + T++E +++ KE RK
Sbjct 307 ----SGVRQERDPIERIKKLVLSHDLATEKELKDMEKEIRK 343
> ath:AT1G24180 IAR4; IAR4; oxidoreductase, acting on the aldehyde
or oxo group of donors, disulfide as acceptor / pyruvate
dehydrogenase (acetyl-transferring) (EC:1.2.4.1); K00161 pyruvate
dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=393
Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 36/101 (35%), Positives = 53/101 (52%), Gaps = 10/101 (9%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
+ +++DG D A A K A++ L N P+++E TYR HS SD S YR E+
Sbjct 253 VPGLKVDGMDALAVKQACKFAKEHALK-NGPIILEMDTYRYHGHSMSDPGSTYRTRDEI- 310
Query 79 AWNASGIL----PIARLRKYLAHEGWWTDEEEEELRKESRK 115
SG+ PI R+RK L T++E +++ KE RK
Sbjct 311 ----SGVRQVRDPIERVRKLLLTHDIATEKELKDMEKEIRK 347
> mmu:18597 Pdha1, Pdha-1; pyruvate dehydrogenase E1 alpha 1 (EC:1.2.4.1);
K00161 pyruvate dehydrogenase E1 component subunit
alpha [EC:1.2.4.1]
Length=390
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ ATK A P+LME TYR HS SD +YR E++
Sbjct 249 IPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 308
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI L+ + + + EE +E+ E RK
Sbjct 309 EVRSKSD-PIMLLKDRMVNSNLASVEELKEIDVEVRK 344
> dre:406702 pdha1a, im:6895726, pdha1, wu:fd18b01, wu:fo96f03,
zgc:73271, zgc:86692; pyruvate dehydrogenase (lipoamide) alpha
1a (EC:1.2.4.1); K00161 pyruvate dehydrogenase E1 component
subunit alpha [EC:1.2.4.1]
Length=393
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ ATK A + P+LME TYR HS SD +YR E++
Sbjct 252 IPGLRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 311
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI+ L+ + + EE +E+ E RK
Sbjct 312 EVRSKSD-PISLLKDRMLSNNMASVEELKEIDVEVRK 347
> cel:T05H10.6 hypothetical protein; K00161 pyruvate dehydrogenase
E1 component subunit alpha [EC:1.2.4.1]
Length=414
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
+ I +DG D+ A ATK A++ P++ME TYR HS SD ++YR E++
Sbjct 260 VPGIWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQ 319
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQMK 122
+ PI + + T+EE + + KE RK + E +K
Sbjct 320 EVRKTRD-PITGFKDRIITSSLATEEELKAIDKEVRKEVDEALK 362
> hsa:5160 PDHA1, PDHA, PDHCE1A, PHE1A; pyruvate dehydrogenase
(lipoamide) alpha 1 (EC:1.2.4.1); K00161 pyruvate dehydrogenase
E1 component subunit alpha [EC:1.2.4.1]
Length=390
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ AT+ A P+LME TYR HS SD +YR E++
Sbjct 249 IPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 308
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI L+ + + + EE +E+ E RK
Sbjct 309 EVRSKSD-PIMLLKDRMVNSNLASVEELKEIDVEVRK 344
> xla:446473 pdha1-a, MGC79036, pdha, pdha1, pdhce1a, phe1a; pyruvate
dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1); K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=400
Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ ATK A P+LME TYR HS SD +YR E++
Sbjct 259 IPGLRVDGMDVLCVREATKFAADHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 318
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI L+ + + + EE +E+ E RK
Sbjct 319 EVRSKSD-PITLLKDRMLNNNLSSVEELKEIDVEVRK 354
> pfa:PF11_0256 pyruvate dehydrogenase E1 component, alpha subunit,
putative; K00161 pyruvate dehydrogenase E1 component subunit
alpha [EC:1.2.4.1]
Length=608
Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 5/109 (4%)
Query 13 RGISYGIQTIRIDGNDLFASF-LATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAY 71
+G ++ I T ++DGND+ + LA K+ +Q+ T+ P+++E +TYR HS +D
Sbjct 416 KGKAFNIDTFKVDGNDVLTIYKLAKKKIQQIRNRTSGPIIIEAITYRAKGHSLADPDE-L 474
Query 72 RPPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRKYMLEQ 120
R E +W PI L Y+ + E+++K ++ +L+Q
Sbjct 475 RIKEEKTSWKKRD--PILFLSSYMKKYNLVQESYFEQVKKNTQT-LLQQ 520
> hsa:5161 PDHA2, MGC149517, MGC149518, PDHAL; pyruvate dehydrogenase
(lipoamide) alpha 2 (EC:1.2.4.1); K00161 pyruvate dehydrogenase
E1 component subunit alpha [EC:1.2.4.1]
Length=388
Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats.
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +++DG D+ ATK A P+LME TYR HS SD +YR E++
Sbjct 247 IPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 306
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
S PI L+ + + T EE +E+ E RK
Sbjct 307 EVR-SKRDPIIILQDRMVNSKLATVEELKEIGAEVRK 342
> xla:447434 pdha1-b, MGC132282, MGC80338, pdha, pdhce1a, phe1a;
pyruvate dehydrogenase (lipoamide) alpha 1 (EC:1.2.4.1);
K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=400
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ ATK A P+LME TYR HS SD +YR E++
Sbjct 259 IPGLRVDGMDVLCVREATKFAADHRRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 318
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI L+ + + EE +E+ E RK
Sbjct 319 EVRSKSD-PITLLKDRMLNNNLSNVEELKEIDVEVRK 354
> dre:436672 pdha1b, Pdha1, wu:fp73b04, zgc:92705; pyruvate dehydrogenase
(lipoamide) alpha 1b (EC:1.2.4.1); K00161 pyruvate
dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=393
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R+DG D+ ATK A P+LME TYR HS SD +YR E++
Sbjct 252 IPGLRVDGMDVLGVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQ 311
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI L+ + + EE +++ + RK
Sbjct 312 EVRSKSD-PITTLKDRMISSNMASLEEIKDIDADIRK 347
> mmu:18598 Pdha2, Pdhal; pyruvate dehydrogenase E1 alpha 2 (EC:1.2.4.1);
K00161 pyruvate dehydrogenase E1 component subunit
alpha [EC:1.2.4.1]
Length=391
Score = 41.2 bits (95), Expect = 8e-04, Method: Composition-based stats.
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query 19 IQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYRPPGELE 78
I +R++G D+ ATK A P++ME TYR HS SD +YR E+
Sbjct 250 IPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRSREEVH 309
Query 79 AWNASGILPIARLRKYLAHEGWWTDEEEEELRKESRK 115
+ PI LR+ + EE +E+ + +K
Sbjct 310 NVRSKSD-PIMLLRERIISNNLSNIEELKEIDADVKK 345
> tgo:TGME49_045670 pyruvate dehydrogenase, putative (EC:1.2.4.1)
Length=635
Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats.
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 3/92 (3%)
Query 13 RGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYR 72
R S+G+ + +DG D+ A A ++A P L+E +TYR HS +D R
Sbjct 454 RAESFGVAGVEVDGMDVLAVRGAARRAIDRARRGEGPTLIEALTYRFRGHSVADPDEM-R 512
Query 73 PPGELEAWNASGILPIARLRKYLAHEGWWTDE 104
+ EAW PI + L G+ +DE
Sbjct 513 AVKQKEAWVVRD--PIKSFEEELKRLGYASDE 542
> ath:AT1G01090 PDH-E1 ALPHA (PYRUVATE DEHYDROGENASE E1 ALPHA);
pyruvate dehydrogenase (acetyl-transferring) (EC:1.2.4.1);
K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Length=428
Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats.
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%)
Query 13 RGISYGIQTIRIDGNDLFASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYR 72
+G ++G+ + +DG D+ K+A P L+E TYR HS +D R
Sbjct 276 KGPAFGMPGVHVDGMDVLKVREVAKEAVTRARRGEGPTLVECETYRFRGHSLADPDE-LR 334
Query 73 PPGELEAWNASGILPIARLRKYLAHEGWWTDEEEEELRKE 112
E + A PIA L+KYL + E + + K+
Sbjct 335 DAAEKAKYAARD--PIAALKKYLIENKLAKEAELKSIEKK 372
> ath:AT1G02980 CUL2; CUL2 (CULLIN 2); ubiquitin protein ligase
binding
Length=742
Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats.
Identities = 13/26 (50%), Positives = 16/26 (61%), Gaps = 0/26 (0%)
Query 22 IRIDGNDLFASFLATKQARQLILDTN 47
+ I DLFA F KQAR+L+ D N
Sbjct 425 VYISDKDLFAEFFRKKQARRLLFDRN 450
> dre:566491 bcl11ab, si:ch211-127m10.2; B-cell CLL/lymphoma 11Ab
Length=776
Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats.
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query 30 FASFLATKQARQLILDTNEPVLMEFMTYRVGQHSTSDDSSAYR-PPGELEAWNASG 84
A + A++Q + IL+ + F T +HS+ + S + PPGEL+ ASG
Sbjct 603 LAGYAASRQLKDPILNFGDSRQSPFAT--SSEHSSENGSLRFSTPPGELDGGTASG 656
> pfa:PF08_0138 RIF; rifin; K13851 repetitive interspersed family
protein
Length=375
Score = 28.1 bits (61), Expect = 6.7, Method: Composition-based stats.
Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query 6 AGDGIAIRGISYGIQTIRIDG--NDLFASFLATKQARQLILDTN 47
AGD ++ +S+G++ R+D D+F +F+ TK ++ N
Sbjct 195 AGDAAGMKVVSFGLKHFRVDELFPDIFKNFVNTKPYNEITTIAN 238
> cel:C07A9.6 ugt-60; UDP-GlucuronosylTransferase family member
(ugt-60)
Length=507
Score = 28.1 bits (61), Expect = 7.6, Method: Composition-based stats.
Identities = 10/25 (40%), Positives = 17/25 (68%), Gaps = 0/25 (0%)
Query 96 AHEGWWTDEEEEELRKESRKYMLEQ 120
AH+ WWT +E +++R E+ + ML
Sbjct 100 AHDLWWTGQEFKDMRVEACEQMLRH 124
Lambda K H
0.317 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2008132680
Database: egene_temp_file_orthology_annotation_similarity_blast_database_865
Posted date: Sep 17, 2011 11:19 AM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40