bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_2997_orf4
Length=315
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_083850 peptidyl-prolyl isomerase, putative (EC:5.2.... 298 2e-80
tpv:TP02_0901 peptidyl-prolyl cis-trans isomerase; K01802 pept... 276 8e-74
pfa:PFL2275c FKBP35; FK506-binding protein (FKBP)-type peptidy... 248 2e-65
bbo:BBOV_I000280 16.m00703; peptidylprolyl isomerase 231 4e-60
ath:AT5G48570 peptidyl-prolyl cis-trans isomerase, putative / ... 173 6e-43
ath:AT3G25230 ROF1; ROF1 (ROTAMASE FKBP 1); FK506 binding / ca... 172 1e-42
xla:431968 hypothetical protein MGC83716; K09571 FK506-binding... 143 8e-34
xla:414546 fkbp4, HBI, MGC81078, PPIase, fkbp52, fkbp59, hsp56... 143 8e-34
hsa:2288 FKBP4, FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p5... 143 1e-33
dre:321795 fkbp4, wu:fb34f09; FK506 binding protein 4 (EC:5.2.... 141 3e-33
mmu:94244 Fkbp6, 1700008G22Rik, 36kDa, AU017274, D5Ertd724e, F... 137 4e-32
xla:432298 fkbp6, MGC80316; FK506 binding protein 6, 36kDa (EC... 137 4e-32
mmu:14228 Fkbp4, 59kDa, AL022792, AW208983, FKBP-4, FKBP-52, F... 137 5e-32
hsa:8468 FKBP6, FKBP36, MGC87179, PPIase; FK506 binding protei... 135 2e-31
hsa:2289 FKBP5, AIG6, FKBP51, FKBP54, MGC111006, P54, PPIase, ... 134 4e-31
mmu:14229 Fkbp5, 51kDa, D17Ertd592e, Dit1, FKBP-5, FKBP51; FK5... 134 5e-31
ath:AT3G21640 TWD1; TWD1 (TWISTED DWARF 1); FK506 binding / ca... 128 2e-29
cel:F31D4.3 fkb-6; FK506-Binding protein family member (fkb-6)... 125 2e-28
dre:368924 fkbp5, si:zc263a23.8, wu:fc31g11, wu:fl87b03, zgc:6... 121 4e-27
xla:379069 fkbp1a, MGC52785; similar to FK506 binding protein ... 119 2e-26
dre:393858 fkbp8, MGC77672, zgc:77672; FK506 binding protein 8... 118 3e-26
dre:798767 CG5482-like 118 3e-26
xla:447040 fkbp1a, MGC82987, fkbp10; FK506 binding protein 1A,... 116 1e-25
hsa:2280 FKBP1A, FKBP-12, FKBP1, FKBP12, PKC12, PKCI2, PPIASE;... 115 2e-25
xla:495188 fkbp8; FK506 binding protein 8, 38kDa; K09574 FK506... 115 2e-25
cel:Y18D10A.19 fkb-2; FK506-Binding protein family member (fkb-2) 114 3e-25
dre:449552 fkbp1ab, zgc:103752; FK506 binding protein 1Ab; K01... 114 4e-25
dre:335335 fkbp1aa, fj02g10, wu:fj02g10, zgc:73373; FK506 bind... 111 3e-24
mmu:14225 Fkbp1a, 12kDa, FKBP12, FKBP12-T1, FKBP12-T2, Fkbp, F... 110 8e-24
cel:F36H1.1 fkb-1; FK506-Binding protein family member (fkb-1)... 109 2e-23
hsa:23770 FKBP8, FKBP38, FKBPr38; FK506 binding protein 8, 38k... 108 2e-23
dre:393785 fkbp1b, MGC73381, zgc:73381; FK506 binding protein ... 108 2e-23
sce:YNL135C FPR1, FKB1, RBP1; Fpr1p (EC:5.2.1.8); K09568 FK506... 106 9e-23
ath:AT4G25340 immunophilin-related / FKBP-type peptidyl-prolyl... 105 2e-22
dre:402839 fkbp6, im:5411885, si:dkey-189h5.5; FK506 binding p... 104 3e-22
mmu:14226 Fkbp1b, 12.6kDa, AW494148, FKBP12.6; FK506 binding p... 104 5e-22
hsa:2281 FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase; FK506... 103 6e-22
xla:399004 fkbp1b, MGC68829, PPIase, fkbp12.6, fkbp1l, otk4, p... 103 6e-22
ath:AT3G54010 PAS1; PAS1 (PASTICCINO 1); FK506 binding / bindi... 103 8e-22
ath:AT3G55520 immunophilin, putative / FKBP-type peptidyl-prol... 103 1e-21
sce:YDR519W FPR2, FKB2; Fpr2p (EC:5.2.1.8); K09569 FK506-bindi... 102 1e-21
xla:379180 fkbp2, MGC130827, MGC53657; FK506 binding protein 2... 102 2e-21
xla:443985 MGC80429 protein; K01802 peptidylprolyl isomerase [... 102 2e-21
mmu:14232 Fkbp8, 38kDa, FKBP-38, FKBP-8, Fkbp38; FK506 binding... 101 4e-21
mmu:14227 Fkbp2, 13kDa, FKBP-2, mFKBP13, mFKBP2; FK506 binding... 101 5e-21
hsa:2286 FKBP2, FKBP-13, PPIase; FK506 binding protein 2, 13kD... 100 8e-21
ath:AT5G48580 FKBP15-2; FK506 binding / peptidyl-prolyl cis-tr... 97.1 7e-20
dre:100149392 aryl hydrocarbon receptor interacting protein-like 96.3 1e-19
dre:497400 im:7140236; si:ch211-13k12.1 95.9 2e-19
dre:334795 aip, MGC101101, wu:fa03h10, zgc:101101; aryl hydroc... 95.1 3e-19
> tgo:TGME49_083850 peptidyl-prolyl isomerase, putative (EC:5.2.1.8);
K01802 peptidylprolyl isomerase [EC:5.2.1.8]
Length=521
Score = 298 bits (763), Expect = 2e-80, Method: Compositional matrix adjust.
Identities = 156/302 (51%), Positives = 208/302 (68%), Gaps = 9/302 (2%)
Query 17 GSC--CGGHAHCDGAPPPAAAAAAAAAAADTSPPHAADTEVDVS-GDGGVIKRVLVQGTG 73
G+C HAH + + + D P D ++S GD GV K++L +G G
Sbjct 3 GTCEEASSHAHS------HSCCGSGSDKVDVDPASIVDAGEEISSGDKGVFKKILKEGDG 56
Query 74 ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSM 133
+P G EV VHY G L DGT+FDSSRDRDSPF+F++GEGQVI+GWDLGV M GE++M
Sbjct 57 PQPQPGEEVVVHYTGTLLDGTKFDSSRDRDSPFKFIIGEGQVIRGWDLGVMKMKRGERAM 116
Query 134 LTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGN 193
LTIQP YGYG +G+ IPPN+ LKF+VELL K K +W M+V EK++ A EKE+GN
Sbjct 117 LTIQPDYGYGASGSPPVIPPNSVLKFDVELLDSHPKPKDKWEMNVGEKLEGANAEKERGN 176
Query 194 AAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQA 253
AFKK AEAAAAYREGL F + +W+ +++ + +E+ LRLNL+ C + GEF++A
Sbjct 177 EAFKKGGYAEAAAAYREGLDFFSFTENWTDEEREQQKRLELPLRLNLATCCNRLGEFSEA 236
Query 254 IDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKE 313
I++ + A+++D ++SK WYRRGVAR A G LDEAR D AA++DPKNVEIR EL+KCK+
Sbjct 237 IEQTTKALEMDPESSKGWYRRGVARMAVGQLDEARHDFVQAAKLDPKNVEIRRELEKCKK 296
Query 314 KL 315
K+
Sbjct 297 KI 298
> tpv:TP02_0901 peptidyl-prolyl cis-trans isomerase; K01802 peptidylprolyl
isomerase [EC:5.2.1.8]
Length=460
Score = 276 bits (705), Expect = 8e-74, Method: Compositional matrix adjust.
Identities = 137/261 (52%), Positives = 176/261 (67%), Gaps = 1/261 (0%)
Query 55 VDVSGDGGVIKRVLVQGTGERPPK-GYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEG 113
+DVSGDGGV+K VL + PK G EVEVHY GKL+ GT FDSS DR++ F+FVLGEG
Sbjct 5 IDVSGDGGVLKTVLKHSEFDEVPKPGEEVEVHYTGKLDCGTVFDSSYDRNTTFKFVLGEG 64
Query 114 QVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAKQR 173
VIKGWD+GV TM +GEK++L IQP YGYG++GAG +IPPNA L FE+ELL+FR K K +
Sbjct 65 SVIKGWDVGVGTMKMGEKALLVIQPEYGYGKSGAGDSIPPNAVLHFEIELLNFRVKPKNK 124
Query 174 WAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVE 233
W +S++EK+QA+ D K GN F + + A + Y EGL +L SS W + L +
Sbjct 125 WELSIDEKLQASVDVKVDGNNKFSQGNYRGAISMYLEGLEYLSESSEWPDESMKLANVTK 184
Query 234 VSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAA 293
+ LNLSNCYLK EF A AS A+KLD + KA +RR VAR + LLD A DL
Sbjct 185 LQCYLNLSNCYLKVSEFRDAEKNASEALKLDRNSVKALFRRAVARLNYDLLDGAIEDLNN 244
Query 294 AARIDPKNVEIRNELKKCKEK 314
++DP NV+ +N LK K++
Sbjct 245 LLKLDPDNVDGQNYLKLAKQR 265
> pfa:PFL2275c FKBP35; FK506-binding protein (FKBP)-type peptidyl-propyl
isomerase (EC:5.2.1.8); K01802 peptidylprolyl isomerase
[EC:5.2.1.8]
Length=304
Score = 248 bits (632), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 127/266 (47%), Positives = 174/266 (65%), Gaps = 5/266 (1%)
Query 55 VDVSGDGGVIKRVLVQGT-GER--PPKGYEVEVHYVGKLED-GTQFDSSRDRDSPFRFVL 110
V+++ DGGVIK +L +G GE P KG EV VHYVGKLE G FDSS DR+ PF+F L
Sbjct 10 VELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPFKFHL 69
Query 111 GEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKA 170
+G+VIKGWD+ V++M EK ++ I+ YGYG+ G G +IP N+ L FE+ELLSFR
Sbjct 70 EQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGESIPGNSVLLFEIELLSFREAK 129
Query 171 KQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQ-QQTLK 229
K + + EEK+Q+A D KE+GN FKK ++ EA Y+E L F H+ W Q K
Sbjct 130 KSIYDYTDEEKVQSAFDIKEEGNEFFKKNEINEAIVKYKEALDFFIHTEEWDDQILLDKK 189
Query 230 LSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARS 289
++E+S LNL+ CY K ++ +AID AS +K+D+ N KA Y+ GVA FG L+EA+
Sbjct 190 KNIEISCNLNLATCYNKNKDYPKAIDHASKVLKIDKNNVKALYKLGVANMYFGFLEEAKE 249
Query 290 DLAAAARIDPKNVEIRNELKKCKEKL 315
+L AA ++P N++IRN + C KL
Sbjct 250 NLYKAASLNPNNLDIRNSYELCVNKL 275
> bbo:BBOV_I000280 16.m00703; peptidylprolyl isomerase
Length=460
Score = 231 bits (588), Expect = 4e-60, Method: Compositional matrix adjust.
Identities = 113/262 (43%), Positives = 163/262 (62%), Gaps = 1/262 (0%)
Query 55 VDVSGDGGVIKRVLVQGT-GERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEG 113
+D++GD GV+K +L + E+P G+EVEVHY GKL+ G FDSS R++ F+F+LG G
Sbjct 5 IDLTGDAGVVKTILTEAKYDEKPENGHEVEVHYTGKLDTGVVFDSSHKRNATFKFILGAG 64
Query 114 QVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAKQR 173
VIKGWD+GVA+M +GEK +L IQP YGYG +GAG +IPPN+ L FE+EL++ R K K
Sbjct 65 NVIKGWDVGVASMKIGEKCLLVIQPEYGYGASGAGSSIPPNSVLHFEIELINSRPKPKDC 124
Query 174 WAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVE 233
MS EE+IQAA D K GN F A + Y +G+ +L + WS + + + ++
Sbjct 125 DDMSTEERIQAATDAKAAGNDKFLHGRYRAAISMYEDGVRYLANRDEWSDEARKVSDLIK 184
Query 234 VSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAA 293
+ LNL+NC++KT ++ A A+ A++LD + K YRR ++R EA DL
Sbjct 185 LQCHLNLANCFIKTEDYRNAEVNATEALRLDASSVKGLYRRALSRVKMESFAEAVEDLTH 244
Query 294 AARIDPKNVEIRNELKKCKEKL 315
+++P N + N K K KL
Sbjct 245 LLKVEPSNGDAANLYKIAKTKL 266
> ath:AT5G48570 peptidyl-prolyl cis-trans isomerase, putative
/ FK506-binding protein, putative; K01802 peptidylprolyl isomerase
[EC:5.2.1.8]
Length=578
Score = 173 bits (439), Expect = 6e-43, Method: Compositional matrix adjust.
Identities = 99/270 (36%), Positives = 158/270 (58%), Gaps = 8/270 (2%)
Query 53 TEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQF---DSSRDRDSPFRF 108
T V+V+ D VIK++L +G G ERP +G V++ +GKL+DGT + + PF F
Sbjct 272 TVVEVTDDRKVIKKILKEGEGYERPNEGAIVKLKLIGKLQDGTTVFVKKGHEEDEEPFEF 331
Query 109 VLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAG---GTIPPNATLKFEVELLS 165
+ E QVI+G + V M GE +++TI P Y +G + + IPPN+T+ +EVEL+S
Sbjct 332 KIDEEQVIEGLEKAVMGMKKGEVALITISPEYAFGSSESKQELAVIPPNSTVYYEVELVS 391
Query 166 FRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQ 225
F K K+ W M+ +E+I+AA +KE+GN FK A A+ Y G+ ++E+ S + ++
Sbjct 392 F-IKEKESWDMNTQERIEAAGKKKEEGNVLFKAGKYARASKRYERGVKYIEYDSTFDEEE 450
Query 226 QTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLD 285
+ ++++ LN + C LK ++ +A ++ +++D +N KA YRR A LD
Sbjct 451 KKKSKDLKIACNLNDAACKLKLKDYKEAAKLSTKVLEMDSRNVKAMYRRAHAYLETADLD 510
Query 286 EARSDLAAAARIDPKNVEIRNELKKCKEKL 315
A D+ A IDP N E++ E KK KEK+
Sbjct 511 LAELDIKKALEIDPDNKEVKIEYKKLKEKV 540
Score = 135 bits (340), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 79/194 (40%), Positives = 110/194 (56%), Gaps = 20/194 (10%)
Query 43 ADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRD 101
AD++P E+++ G G+ K+++ + + P G EVEVHY G L DGT+FDSSRD
Sbjct 29 ADSAPYLKIGEEMEI-GKSGLKKKLVKECEKWDTPENGDEVEVHYTGTLLDGTKFDSSRD 87
Query 102 RDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEV 161
R +PF+F LG+G VIKGWDLG+ TM GE ++ TI P YGE G+ TIPPNATL+F+V
Sbjct 88 RGTPFKFTLGQGHVIKGWDLGIKTMKKGENAIFTIPPELAYGETGSPPTIPPNATLQFDV 147
Query 162 ELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYR------------ 209
EL+++R+ V +KI ++ E K KDL E Y
Sbjct 148 ELIAWRSVKDICGDGGVSKKIIVEGEKWE------KPKDLDEVYVKYEARLEDGTIVGKS 201
Query 210 EGLAFLEHSSHWSP 223
+G+ F H+ P
Sbjct 202 DGVEFTVKEGHFCP 215
Score = 85.1 bits (209), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 56/154 (36%), Positives = 78/154 (50%), Gaps = 21/154 (13%)
Query 32 PAAAAAAAAAAADTSPPHAA---DTEV-------DVSGDGGVIKRVLVQGTG-ERPPKGY 80
P A + T PP+A D E+ D+ GDGGV K+++V+G E+P
Sbjct 123 PPELAYGETGSPPTIPPNATLQFDVELIAWRSVKDICGDGGVSKKIIVEGEKWEKPKDLD 182
Query 81 EVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTY 140
EV V Y +LEDGT S F + EG V TM GEK +LT++P Y
Sbjct 183 EVYVKYEARLEDGTIVGKS----DGVEFTVKEGHFCPALSKAVKTMKRGEKVLLTVKPQY 238
Query 141 GYGEAGAGGT------IPPNATLKFEVELLSFRA 168
G+GE G + IPPNATL+ ++EL+S++
Sbjct 239 GFGEFGRPASDGLQAAIPPNATLQIDLELVSWKT 272
> ath:AT3G25230 ROF1; ROF1 (ROTAMASE FKBP 1); FK506 binding /
calmodulin binding / peptidyl-prolyl cis-trans isomerase; K09571
FK506-binding protein 4/5 [EC:5.2.1.8]
Length=562
Score = 172 bits (436), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 104/293 (35%), Positives = 164/293 (55%), Gaps = 17/293 (5%)
Query 39 AAAAADTSPPHAA----------DTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYV 87
A+A PP+A T +V+ D V+K+VL +G G ERP +G V+V +
Sbjct 239 ASAGEGAVPPNATLEINLELVSWKTVSEVTDDNKVVKKVLKEGDGYERPNEGAVVKVKLI 298
Query 88 GKLEDGTQF--DSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEA 145
GKL+DGT F + + PF F E QV+ G D V M GE +++TI P Y +G
Sbjct 299 GKLQDGTVFLKKGHGENEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYAFGSN 358
Query 146 GAG---GTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLA 202
+ +PPN+T+ +EV+LL+F K ++ W M+ EEKI+AA+ +KE+GN+ FK +
Sbjct 359 ESQQELAVVPPNSTVTYEVDLLTFD-KERESWDMNTEEKIEAASKKKEEGNSKFKGGKYS 417
Query 203 EAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIK 262
A+ Y + + F+E+ + +S +++ +++V+ LN + C LK ++ QA + ++
Sbjct 418 LASKRYEKAVKFIEYDTSFSEEEKKQAKALKVACNLNDAACKLKLKDYKQAEKLCTKVLE 477
Query 263 LDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEKL 315
L+ N KA YRR A LD A D+ A IDP N E++ E K+ KEK+
Sbjct 478 LESTNVKALYRRAQAYMELSDLDLAEFDVKKALEIDPNNREVKLEQKRLKEKM 530
Score = 131 bits (329), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 62/106 (58%), Positives = 79/106 (74%), Gaps = 1/106 (0%)
Query 62 GVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWD 120
G+ K++L +G G E P G EVEVHY G L DGT+FDSSRDR +PF+F LG+GQVIKGWD
Sbjct 39 GLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGTKFDSSRDRATPFKFTLGQGQVIKGWD 98
Query 121 LGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
+G+ TM GE ++ TI YGE+G+ TIP NATL+F+VELL +
Sbjct 99 IGIKTMKKGENAVFTIPAELAYGESGSPPTIPANATLQFDVELLKW 144
Score = 79.3 bits (194), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 20/178 (11%)
Query 32 PAAAAAAAAAAADTSPPHAA----------DTEVDVSGDGGVIKRVLVQGTGERPPKGY- 80
PA A + + T P +A D+ D+ DGGV K++L G PK
Sbjct 115 PAELAYGESGSPPTIPANATLQFDVELLKWDSVKDICKDGGVFKKILAVGEKWENPKDLD 174
Query 81 EVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTY 140
EV V + KLEDGT S F + +G V TM GEK +LT++P Y
Sbjct 175 EVLVKFEAKLEDGTVVGKS----DGVEFTVKDGHFCPALTKAVKTMKKGEKVLLTVKPQY 230
Query 141 GYGEAG----AG-GTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGN 193
G+GE G AG G +PPNATL+ +EL+S++ ++ V +K+ D E+ N
Sbjct 231 GFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEVTDDNKVVKKVLKEGDGYERPN 288
> xla:431968 hypothetical protein MGC83716; K09571 FK506-binding
protein 4/5 [EC:5.2.1.8]
Length=447
Score = 143 bits (361), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 94/293 (32%), Positives = 152/293 (51%), Gaps = 14/293 (4%)
Query 28 GAPPPAAAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHY 86
G+PP A + D D DGG+I+R+ V+G G +P +G VE+H
Sbjct 113 GSPPKIPPNAMLIFEVELFDFQGEDLSQD--EDGGIIRRIRVKGEGYSKPNEGAVVELHL 170
Query 87 VGKLEDGTQFDSSRDRDSPFRFVLGEGQVI---KGWDLGVATMSVGEKSMLTIQPTYGYG 143
G + +G FD + +F +GEG+ I G + + M GE+++L ++P YG+
Sbjct 171 KG-IHNGRVFD-----ERELKFEVGEGESIGIPPGVETAIQQMEKGEEAVLYLKPKYGFS 224
Query 144 EAGAGG-TIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLA 202
G+ IPP A L++++ L SF KAK+ W M+ EEK++ KE+G FK
Sbjct 225 MTGSEKYQIPPGAELQYDIRLKSFE-KAKESWEMNAEEKLEQGCLVKERGTQYFKDGRYR 283
Query 203 EAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIK 262
+A Y++ + +LEH S S ++ S+ ++ LNL+ CYLK GE A++ + A++
Sbjct 284 QATIQYKKIMQWLEHESGLSKEEDAKAKSLILAASLNLAACYLKLGEHRAALEHCNKALE 343
Query 263 LDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEKL 315
D N K +RRG A L+ AR D A ++ P N R +L +C+ ++
Sbjct 344 RDPSNEKGLFRRGEAYMCSNDLELARDDFAKVLQLYPANRAARAQLGQCQIRI 396
Score = 125 bits (315), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 62/118 (52%), Positives = 78/118 (66%), Gaps = 1/118 (0%)
Query 53 TEVDVSGDGGVIKRVLVQGTGERPPK-GYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLG 111
T++ GD GV+K + +GTGE P G +V VHY G L DGT+FDSSRDR F F LG
Sbjct 19 TDITPKGDQGVLKLIKKEGTGENTPMIGDKVSVHYTGWLTDGTKFDSSRDRKDKFTFDLG 78
Query 112 EGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAK 169
+G+VIK WD+ VATM VGE + +P Y YG +G+ IPPNA L FEVEL F+ +
Sbjct 79 KGEVIKAWDIAVATMKVGEICQIICKPEYAYGTSGSPPKIPPNAMLIFEVELFDFQGE 136
> xla:414546 fkbp4, HBI, MGC81078, PPIase, fkbp52, fkbp59, hsp56,
p52; FK506 binding protein 4, 59kDa; K09571 FK506-binding
protein 4/5 [EC:5.2.1.8]
Length=447
Score = 143 bits (360), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 95/293 (32%), Positives = 153/293 (52%), Gaps = 14/293 (4%)
Query 28 GAPPPAAAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHY 86
G+PP A + D D DGG+I+R+ V+G G +P +G VE+H
Sbjct 113 GSPPKIPPNAVLIFEVELFDFQGEDLSQDE--DGGIIRRIRVKGEGYSKPNEGAVVELHL 170
Query 87 VGKLEDGTQFDSSRDRDSPFRFVLGEGQVI---KGWDLGVATMSVGEKSMLTIQPTYGYG 143
G + +G FD + +F +GEG+ I G + + M GE++ L ++P YG+G
Sbjct 171 KG-MHNGRVFD-----ERELKFEVGEGESIGIPPGVETAIQQMEKGEEADLYLKPKYGFG 224
Query 144 EAG-AGGTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLA 202
AG A IPP A L++++ L +F KAK+ W M+ EEK++ KE+G FK
Sbjct 225 IAGSAKYQIPPGAELQYDIRLKNFE-KAKESWEMNAEEKLEQGCLVKERGTKYFKDGRYR 283
Query 203 EAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIK 262
+A Y++ + +LEH S S ++ S+ ++ LNL+ CYLK GE A++ + A++
Sbjct 284 QATIQYKKIVQWLEHESGLSKEEDAKAKSLILAASLNLAACYLKLGEQRAALEYCNKALE 343
Query 263 LDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEKL 315
L+ N K +RRG A L+ AR+D ++ P N R +L C+ ++
Sbjct 344 LEPSNEKGLFRRGEAFMCTNDLEHARNDFTKVLQLYPSNKAARAQLGHCQVRI 396
Score = 124 bits (312), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 64/126 (50%), Positives = 80/126 (63%), Gaps = 3/126 (2%)
Query 47 PPHAADTEVDVS--GDGGVIKRVLVQGTGERPPK-GYEVEVHYVGKLEDGTQFDSSRDRD 103
P H D++ GD GV+K + +GTGE P G +V VHY G L DGT+FDSSRDR
Sbjct 11 PEHFTMDGSDITPKGDQGVLKLIKKEGTGENTPMIGDKVSVHYTGWLTDGTKFDSSRDRK 70
Query 104 SPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVEL 163
F F LG+G+VIK WD+ VATM VGE + +P Y YG +G+ IPPNA L FEVEL
Sbjct 71 DKFTFDLGKGEVIKAWDIAVATMKVGEICQIICKPEYAYGTSGSPPKIPPNAVLIFEVEL 130
Query 164 LSFRAK 169
F+ +
Sbjct 131 FDFQGE 136
> hsa:2288 FKBP4, FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase,
p52; FK506 binding protein 4, 59kDa (EC:5.2.1.8); K09571 FK506-binding
protein 4/5 [EC:5.2.1.8]
Length=459
Score = 143 bits (360), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 86/261 (32%), Positives = 145/261 (55%), Gaps = 12/261 (4%)
Query 60 DGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIK- 117
DGG+I+R+ +G G +P +G VEV G +D FD RF +GEG+ +
Sbjct 147 DGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKL-FDQRE-----LRFEIGEGENLDL 200
Query 118 --GWDLGVATMSVGEKSMLTIQPTYGYGEAGAGG-TIPPNATLKFEVELLSFRAKAKQRW 174
G + + M GE S++ ++P+Y +G G IPPNA LK+E+ L SF KAK+ W
Sbjct 201 PYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE-KAKESW 259
Query 175 AMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEV 234
M+ EEK++ + KE+G FK+ +A Y++ +++LE+ S +S ++ ++ +
Sbjct 260 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRL 319
Query 235 SLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAA 294
+ LNL+ C+LK F+ AI+ + A++LD N K +RRG A A + AR+D
Sbjct 320 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKV 379
Query 295 ARIDPKNVEIRNELKKCKEKL 315
++ P N + +L C++++
Sbjct 380 LQLYPNNKAAKTQLAVCQQRI 400
Score = 124 bits (311), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 64/131 (48%), Positives = 81/131 (61%), Gaps = 1/131 (0%)
Query 38 AAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQF 96
A + A ++P ++ D GV+K + +GTG E P G V VHY G L DGT+F
Sbjct 8 ATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKF 67
Query 97 DSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNAT 156
DSS DR F F LG+G+VIK WD+ +ATM VGE +T +P Y YG AG+ IPPNAT
Sbjct 68 DSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNAT 127
Query 157 LKFEVELLSFR 167
L FEVEL F+
Sbjct 128 LVFEVELFEFK 138
> dre:321795 fkbp4, wu:fb34f09; FK506 binding protein 4 (EC:5.2.1.8);
K09571 FK506-binding protein 4/5 [EC:5.2.1.8]
Length=449
Score = 141 bits (356), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 94/297 (31%), Positives = 153/297 (51%), Gaps = 22/297 (7%)
Query 28 GAPP---PAAAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVE 83
G+PP P A D D E DGG+ +R++ +G G +P +G VE
Sbjct 112 GSPPKIPPNATLLFQVELFDFRGEDITDDE-----DGGITRRIITKGEGYTKPNEGATVE 166
Query 84 VHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGV----ATMSVGEKSMLTIQPT 139
V G ED FD + +F +G+G+ + G LGV M GE+++ TI+P
Sbjct 167 VWLEGSHEDRV-FD-----ERELKFEVGDGENL-GLPLGVEKALQAMEQGEEALFTIKPK 219
Query 140 YGYGEAGAGG-TIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKK 198
YG+G AG+ IPPNATL++++++ +F KAK+ W M+ EK++ + KEKG FK+
Sbjct 220 YGFGTAGSEKYNIPPNATLQYKIKMKAFE-KAKESWEMNTIEKLEQSVIVKEKGTQYFKE 278
Query 199 KDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEAS 258
+A Y+ +++LEH S P + ++ ++ LNL+ CYLK + A++
Sbjct 279 GKYKQAIVQYKRIVSWLEHESSMQPDDEEKAKALRLAAYLNLAMCYLKLQDANPALENCD 338
Query 259 AAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEKL 315
A++LD N KA +RRG A D A+ D + P N ++++ C++ +
Sbjct 339 KALELDANNEKALFRRGEALVVMKEFDMAKVDFQRVIELYPANKAAKSQISICQKHM 395
Score = 135 bits (340), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 68/109 (62%), Positives = 78/109 (71%), Gaps = 1/109 (0%)
Query 60 DGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKG 118
DGGV+K V +GTG E P G +V VHYVG L DG+QFDSSRDR F F LG+GQVIK
Sbjct 25 DGGVLKLVKKEGTGTELPMIGDKVFVHYVGTLLDGSQFDSSRDRGEKFSFELGKGQVIKA 84
Query 119 WDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFR 167
WD+GVATM +GE LT +P Y YG AG+ IPPNATL F+VEL FR
Sbjct 85 WDIGVATMKIGEICQLTCKPEYAYGAAGSPPKIPPNATLLFQVELFDFR 133
> mmu:94244 Fkbp6, 1700008G22Rik, 36kDa, AU017274, D5Ertd724e,
FKBP-6; FK506 binding protein 6 (EC:5.2.1.8); K09572 FK506-binding
protein 6 [EC:5.2.1.8]
Length=327
Score = 137 bits (346), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 93/267 (34%), Positives = 140/267 (52%), Gaps = 12/267 (4%)
Query 55 VDVSGDGGVIKRVLVQGTGERPPKGYEVEVHYVGKLEDGTQ-FDSSRDRDSPFRFVLGEG 113
+D+SGD GV+K ++ +GTG+ V V Y G LE + FDS+ R +P LGE
Sbjct 30 LDISGDRGVLKDIIREGTGDTVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGED 89
Query 114 QVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF--RAKAK 171
+ G +LG+ +M GE + +P Y YG G IPPNAT+ FE+EL+ F A++
Sbjct 90 ITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESD 149
Query 172 QRWAMSVEEK--------IQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSP 223
+ A+S E++ ++ AA E+E GN F++ +A Y+ L L
Sbjct 150 KFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLATCE 209
Query 224 QQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGL 283
+Q ++ +V + L LNLS YLK A A+ A+ +D++N+KA +R G A
Sbjct 210 EQHLVEPAVLLVL-LNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTE 268
Query 284 LDEARSDLAAAARIDPKNVEIRNELKK 310
+ AR L A + P N +I NELKK
Sbjct 269 YERARDFLVRAQKEQPCNHDINNELKK 295
> xla:432298 fkbp6, MGC80316; FK506 binding protein 6, 36kDa (EC:5.2.1.8);
K09572 FK506-binding protein 6 [EC:5.2.1.8]
Length=304
Score = 137 bits (346), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 90/266 (33%), Positives = 139/266 (52%), Gaps = 12/266 (4%)
Query 56 DVSGDGGVIKRVLVQGTGERPPKGYEVEVHYVGKLEDGTQ-FDSSRDRDSPFRFVLGEGQ 114
DVSGD GV+K V+ G G + P V + Y G LE + FD+S R P LG+
Sbjct 13 DVSGDRGVLKEVIRPGKGGKVPCDATVILKYSGYLEHADKPFDTSCYRRHPRMMKLGQDI 72
Query 115 VIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF--RAKAKQ 172
+ G ++G+ TM GE S P Y YG G IPP+AT FE+ELL F A++
Sbjct 73 TLAGMEIGLLTMQRGELSRFLFSPKYAYGTLGCPSLIPPSATALFEIELLDFLDTAESDL 132
Query 173 RWAMS--------VEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQ 224
+A+S +++ I+ A E+E GN FK+ +A Y+ + L + +
Sbjct 133 FYALSPEVQATFPLDKIIKIAGTEREFGNYLFKRNRFNDARDRYKRASSLLSCKASCDEE 192
Query 225 QQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLL 284
+ L+ + ++ + LNLS YLK ++A+ A+ +D +N+KA +R G A
Sbjct 193 SKLLE-AAQLFVDLNLSLTYLKLERPSRALKWGEKALSIDNRNTKALFRCGQACLEMREY 251
Query 285 DEARSDLAAAARIDPKNVEIRNELKK 310
D+AR+ L A R++P N +I NEL++
Sbjct 252 DKARNFLLKAQRLEPFNPDINNELRR 277
> mmu:14228 Fkbp4, 59kDa, AL022792, AW208983, FKBP-4, FKBP-52,
FKBP52, FKPB52, p59; FK506 binding protein 4 (EC:5.2.1.8);
K09571 FK506-binding protein 4/5 [EC:5.2.1.8]
Length=458
Score = 137 bits (345), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 87/260 (33%), Positives = 142/260 (54%), Gaps = 12/260 (4%)
Query 60 DGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIK- 117
DGG+I+R+ +G G RP G VEV G +D FD F +GEG+ +
Sbjct 147 DGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRL-FDQRE-----LCFEVGEGESLDL 200
Query 118 --GWDLGVATMSVGEKSMLTIQPTYGYGEAGAGG-TIPPNATLKFEVELLSFRAKAKQRW 174
G + + M GE S++ ++P+Y +G G IPP+A L++EV L SF KAK+ W
Sbjct 201 PCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFE-KAKESW 259
Query 175 AMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEV 234
MS EK++ + KE+G A FK+ +A Y++ +++LE+ S +S ++ ++ +
Sbjct 260 EMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRL 319
Query 235 SLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAA 294
+ LNL+ C+LK F+ AI+ + A++LD N K +RRG A A D AR+D
Sbjct 320 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKV 379
Query 295 ARIDPKNVEIRNELKKCKEK 314
++ P N + +L C+++
Sbjct 380 LQLYPSNKAAKTQLAVCQQR 399
Score = 124 bits (311), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 66/131 (50%), Positives = 81/131 (61%), Gaps = 1/131 (0%)
Query 38 AAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQF 96
AA A ++P ++ D GV+K + +GTG E P G V VHY G L DGT+F
Sbjct 8 AAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKF 67
Query 97 DSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNAT 156
DSS DR F F LG+G+VIK WD+ VATM VGE +T +P Y YG AG+ IPPNAT
Sbjct 68 DSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGAAGSPPKIPPNAT 127
Query 157 LKFEVELLSFR 167
L FEVEL F+
Sbjct 128 LVFEVELFEFK 138
> hsa:8468 FKBP6, FKBP36, MGC87179, PPIase; FK506 binding protein
6, 36kDa (EC:5.2.1.8); K09572 FK506-binding protein 6 [EC:5.2.1.8]
Length=322
Score = 135 bits (339), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 94/267 (35%), Positives = 139/267 (52%), Gaps = 12/267 (4%)
Query 55 VDVSGDGGVIKRVLVQGTGERPPKGYEVEVHYVGKLEDGTQ-FDSSRDRDSPFRFVLGEG 113
+D+SGD GV+K V+ +G G+ V V Y G LE + FDS+ R +P LGE
Sbjct 25 LDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGED 84
Query 114 QVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFR--AKAK 171
+ G +LG+ +M GE + +P Y YG G IPPN T+ FE+ELL F A++
Sbjct 85 ITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESD 144
Query 172 QRWAMSVEEK--------IQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSP 223
+ A+S E++ ++ AA E+E GN F++ +A Y+ L L S P
Sbjct 145 KFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSA-PP 203
Query 224 QQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGL 283
++Q L + ++ + LNLS YLK A+ A+ +D+KN+KA +R G A
Sbjct 204 EEQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACLLLTE 263
Query 284 LDEARSDLAAAARIDPKNVEIRNELKK 310
+AR L A + P N +I NELKK
Sbjct 264 YQKARDFLVRAQKEQPFNHDINNELKK 290
> hsa:2289 FKBP5, AIG6, FKBP51, FKBP54, MGC111006, P54, PPIase,
Ptg-10; FK506 binding protein 5 (EC:5.2.1.8); K09571 FK506-binding
protein 4/5 [EC:5.2.1.8]
Length=457
Score = 134 bits (338), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 92/264 (34%), Positives = 137/264 (51%), Gaps = 12/264 (4%)
Query 56 DVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQ 114
D+ DGG+I+R +G G P +G VE+H G+ G FD RD F +GEG+
Sbjct 141 DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC---RDVAF--TVGEGE 194
Query 115 ---VIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGT-IPPNATLKFEVELLSFRAKA 170
+ G D + M E+ +L + P YG+GEAG I PNA L +EV L SF KA
Sbjct 195 DHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE-KA 253
Query 171 KQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKL 230
K+ W M +EK++ AA KEKG FK +A Y + +++LE S ++
Sbjct 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASE 313
Query 231 SVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSD 290
S ++ LNL+ CYLK E+ +A++ A+ LD N K YRRG A+ + A+ D
Sbjct 314 SFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGD 373
Query 291 LAAAARIDPKNVEIRNELKKCKEK 314
++P+N R ++ C++K
Sbjct 374 FEKVLEVNPQNKAARLQISMCQKK 397
Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 62/110 (56%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
Query 60 DGGVIKRVLVQGTGERPPK-GYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKG 118
D GV+K V G GE P G +V VHY GKL +G +FDSS DR+ PF F LG+GQVIK
Sbjct 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKA 89
Query 119 WDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRA 168
WD+GVATM GE L +P Y YG AG+ IP NATL FE+ELL F+
Sbjct 90 WDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG 139
> mmu:14229 Fkbp5, 51kDa, D17Ertd592e, Dit1, FKBP-5, FKBP51; FK506
binding protein 5 (EC:5.2.1.8); K09571 FK506-binding protein
4/5 [EC:5.2.1.8]
Length=456
Score = 134 bits (337), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 94/264 (35%), Positives = 136/264 (51%), Gaps = 12/264 (4%)
Query 56 DVSGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQ 114
D+ D GVI+R+ +G G P +G V+VH G G FD RD F V+GEG+
Sbjct 141 DLFEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCC-GGRTFDC---RDVVF--VVGEGE 194
Query 115 ---VIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGA-GGTIPPNATLKFEVELLSFRAKA 170
+ G D + M E+ +L + P YG+GEAG I PNA L +EV L SF KA
Sbjct 195 DHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFE-KA 253
Query 171 KQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKL 230
K+ W M +EK+ AA KEKG FK +A YR+ +++LE S ++
Sbjct 254 KESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASE 313
Query 231 SVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSD 290
S ++ LNL+ CYLK E+ +A++ A+ LD N K YRRG A+ + A+ D
Sbjct 314 SFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGD 373
Query 291 LAAAARIDPKNVEIRNELKKCKEK 314
++P+N R ++ C+ K
Sbjct 374 FEKVLAVNPQNRAARLQISMCQRK 397
Score = 117 bits (293), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 60/115 (52%), Positives = 72/115 (62%), Gaps = 1/115 (0%)
Query 54 EVDVSGDGGVIKRVLVQGTGERPPK-GYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGE 112
++ D GV+K V GT + P G +V VHY G L DG +FDSS DR PF F LG+
Sbjct 24 DITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQ 83
Query 113 GQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFR 167
GQVIK WD+GV+TM GE L +P Y YG AG IP NATL FE+ELL F+
Sbjct 84 GQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFK 138
> ath:AT3G21640 TWD1; TWD1 (TWISTED DWARF 1); FK506 binding /
calmodulin binding / peptidyl-prolyl cis-trans isomerase
Length=365
Score = 128 bits (322), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 88/289 (30%), Positives = 149/289 (51%), Gaps = 9/289 (3%)
Query 34 AAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTGERPPKGYEVEVHYVGKLEDG 93
+A + + + + P D+E +V D V K+++ +G G +P K +HY ++
Sbjct 23 SAVVHSEPSQEGNVPPKVDSEAEVL-DEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNS 81
Query 94 T-QFDSSRDRDSPFRFVLG-EGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGG-- 149
+F+ + P VLG E + + G +GVA+M GE++++ + YG+ G
Sbjct 82 QHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFP 141
Query 150 TIPPNATLKFEVELLSF--RAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAA 207
+PP A L +EVE++ F + K R M+VEE+I AA K GN+ FK++ L EA
Sbjct 142 NVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQ 201
Query 208 YREGLAFL--EHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDE 265
Y +A++ + + Q + L+V+ LN++ C +K + +AI + + +E
Sbjct 202 YEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEE 261
Query 266 KNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEK 314
KN KA +RRG A+A G +D AR D A + P + IR EL+ E+
Sbjct 262 KNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQ 310
> cel:F31D4.3 fkb-6; FK506-Binding protein family member (fkb-6);
K09571 FK506-binding protein 4/5 [EC:5.2.1.8]
Length=431
Score = 125 bits (315), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 64/111 (57%), Positives = 78/111 (70%), Gaps = 1/111 (0%)
Query 60 DGGVIKRVLVQGTGE-RPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKG 118
DGGV+K + +G G +P G V+VHYVG LE+GT+FDSSRDR F F LG G VIKG
Sbjct 13 DGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTKFDSSRDRGDQFSFNLGRGNVIKG 72
Query 119 WDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAK 169
WDLGVATM+ GE + TI+ YGYG+AG+ IP ATL FEVEL + A+
Sbjct 73 WDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAE 123
Score = 86.7 bits (213), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 77/294 (26%), Positives = 127/294 (43%), Gaps = 15/294 (5%)
Query 28 GAPPPAAAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRVLVQGTGER-PPKGYEVEVHY 86
G+PP A + A D D DG +++ ++V+G+ P +V H
Sbjct 100 GSPPKIPGGATLIFEVELFEWSAEDISPD--RDGTILRTIIVEGSKNSFPNDTSKVLAHC 157
Query 87 VGKLEDGTQFDSSRDRDSPFRFVLGEGQ---VIKGWDLGVATMSVGEKSMLTIQ-PTYGY 142
VG + GT+F + F +GEG + +G + + +GEKS + I+ Y Y
Sbjct 158 VGTYQ-GTEF-----YNREVNFHIGEGSEEGLPEGVERALRRFQLGEKSKIEIRGHKYTY 211
Query 143 GEAG-AGGTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDL 201
G + AG IP NATL+F + L F K W M+ EEK+ AA K++G +K +L
Sbjct 212 GNSPPAGSNIPVNATLEFTIFLKEFE-KVPATWEMTAEEKLDAAKQAKDRGTMYLQKGNL 270
Query 202 AEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAI 261
A Y+ LE+ P++ + ++ LNLS K E + I +
Sbjct 271 KLAYNKYKRAEEVLEYEKSTDPEKMAERETILNGAYLNLSLVCSKQNEQLECIKWCDKVL 330
Query 262 KLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCKEKL 315
+ N KA YR+ A + +A ++P+N ++ C+ +
Sbjct 331 ETKPGNVKALYRKATALLTMNEVRDAMKLFEKIVEVEPENKAAAQQIIVCRNTI 384
> dre:368924 fkbp5, si:zc263a23.8, wu:fc31g11, wu:fl87b03, zgc:64082;
FK506 binding protein 5 (EC:5.2.1.8); K09571 FK506-binding
protein 4/5 [EC:5.2.1.8]
Length=453
Score = 121 bits (303), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 60/118 (50%), Positives = 76/118 (64%), Gaps = 1/118 (0%)
Query 53 TEVDVSGDGGVIKRVLVQGT-GERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLG 111
T V +GD GV K V G GERP G V VHY G+L G +FDSS DR PF F +G
Sbjct 23 TAVTPNGDSGVCKIVKQHGVEGERPMIGDRVFVHYTGRLLSGKKFDSSLDRKEPFVFNVG 82
Query 112 EGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAK 169
+GQVIK WD+ V +M GE ++ +P Y YG AG+ +PPN+TL FE+ELL+FR +
Sbjct 83 KGQVIKAWDICVCSMQKGEVCLMLCKPEYAYGSAGSPPKVPPNSTLVFEIELLNFRGE 140
Score = 115 bits (287), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 89/303 (29%), Positives = 142/303 (46%), Gaps = 20/303 (6%)
Query 26 CDGAPPPAAAAAAAAAAADTSPPHAADTEVDV--------SGDGGVIKRVLVQGTG-ERP 76
C P A +A + P E+++ + DGG+++R+ V+G G P
Sbjct 103 CLMLCKPEYAYGSAGSPPKVPPNSTLVFEIELLNFRGEELTEDGGIVRRIKVKGEGYSNP 162
Query 77 PKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQ---VIKGWDLGVATMSVGEKSM 133
+G V VH G G FDS RD F +GE + V G D + + GE +
Sbjct 163 NEGATVHVHLEGWC-GGRLFDS---RDVTF--AVGESEDVGVPLGVDRAMEKLQKGECCL 216
Query 134 LTIQPTYGYGEAGAG-GTIPPNATLKFEVELLSFRAKAKQRWAMSVEEKIQAAADEKEKG 192
L ++P Y +G+ G I NA L +EV L F KAK+ W M ++EK++ A K+KG
Sbjct 217 LYLKPKYAFGKEGRKEHDIGSNAELLYEVTLKDFE-KAKETWEMDLKEKLERAVLVKQKG 275
Query 193 NAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQ 252
FK A Y+ + +LE +Q ++ + LNL+ CYL+ E++Q
Sbjct 276 TQYFKAGRYNYAVIQYQRIVNWLEMECGNGKEQLQAIQALLLVAHLNLALCYLRLREYSQ 335
Query 253 AIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDPKNVEIRNELKKCK 312
++ + ++LD +N KA YRRG AR A D +++ N R+++ C+
Sbjct 336 TVENCNKVMELDPENEKALYRRGEARLLRNEFSLALMDFKQVLQVNSFNRAARSQILICQ 395
Query 313 EKL 315
K+
Sbjct 396 HKI 398
> xla:379069 fkbp1a, MGC52785; similar to FK506 binding protein
1A, 12kDa (EC:5.2.1.8); K01802 peptidylprolyl isomerase [EC:5.2.1.8]
Length=108
Score = 119 bits (297), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 57/104 (54%), Positives = 73/104 (70%), Gaps = 1/104 (0%)
Query 62 GVIKRVLVQGTGER-PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWD 120
GV + +G G P KG V VHYVG LE+G +FDSSRDR+ PF+F++G +VI+GW+
Sbjct 2 GVQVETITEGDGRTFPKKGQTVVVHYVGSLENGKKFDSSRDRNKPFKFIIGRCEVIRGWE 61
Query 121 LGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELL 164
GVA MSVG+++ LT P + YG G G IPPNATL F+VELL
Sbjct 62 EGVAQMSVGQRARLTCSPDFAYGATGHPGIIPPNATLTFDVELL 105
> dre:393858 fkbp8, MGC77672, zgc:77672; FK506 binding protein
8 (EC:5.2.1.8); K09574 FK506-binding protein 8 [EC:5.2.1.8]
Length=406
Score = 118 bits (295), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 88/274 (32%), Positives = 133/274 (48%), Gaps = 10/274 (3%)
Query 46 SPPHAADTEVDVSGDGGVIKRVLVQGTG--ERPPKGYEVEVHYVGKLEDGTQFDSSRDRD 103
SP + +DV G+G + K+VL G G RP KG V +H L +GT D +D
Sbjct 77 SPSAEPEEWLDVLGNGQLRKKVLEAGAGPDSRPQKGQNVTIHLKTALTNGTVVDELKD-- 134
Query 104 SPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGG-TIPPNATLKFEVE 162
F LG+G V++ DL V M +GEK+++ Y YG G+ +PP+A L EV+
Sbjct 135 --LSFTLGDGDVLQALDLTVQLMEMGEKALIEAAAKYAYGALGSSAPAVPPDADLLLEVQ 192
Query 163 LLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSH-- 220
LLS +A M E+I A ++E+GN +++ D A A +Y L E SS
Sbjct 193 LLSAD-EALDLELMPPSERIILANRKRERGNVHYQRADYAFAVNSYGIALQITEASSRVD 251
Query 221 WSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAA 280
S +++ L ++V N++ LK + A+ + + N KA +R+G A
Sbjct 252 ISQEEEEELLDMKVKCLNNMAAAQLKLDHYEAALRSCVSVLAHQPDNVKALFRKGKVLAL 311
Query 281 FGLLDEARSDLAAAARIDPKNVEIRNELKKCKEK 314
G EA L A +++P N I EL K +K
Sbjct 312 QGEFAEAIKTLKMALKLEPSNKTIHAELSKLVKK 345
> dre:798767 CG5482-like
Length=406
Score = 118 bits (295), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 88/274 (32%), Positives = 133/274 (48%), Gaps = 10/274 (3%)
Query 46 SPPHAADTEVDVSGDGGVIKRVLVQGTG--ERPPKGYEVEVHYVGKLEDGTQFDSSRDRD 103
SP + +DV G+G + K+VL G G RP KG V +H L +GT D +D
Sbjct 77 SPSAEPEEWLDVLGNGQLRKKVLEAGAGPDSRPQKGQNVTIHLKTALTNGTVVDELKD-- 134
Query 104 SPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGG-TIPPNATLKFEVE 162
F LG+G V++ DL V M +GEK+++ Y YG G+ +PP+A L EV+
Sbjct 135 --LSFTLGDGDVLQALDLTVQLMEMGEKALIEAAAKYAYGALGSSAPAVPPDADLLLEVQ 192
Query 163 LLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSH-- 220
LLS +A M E+I A ++E+GN +++ D A A +Y L E SS
Sbjct 193 LLSAD-EALDLELMPPSERIILANRKRERGNVHYQRADYAFAVNSYGIALQITEASSRVD 251
Query 221 WSPQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAA 280
S +++ L ++V N++ LK + A+ + + N KA +R+G A
Sbjct 252 ISQEEEEELLDMKVKCLNNMAAAQLKLDHYEAALRSCVSVLAHQPDNVKALFRKGKVLAL 311
Query 281 FGLLDEARSDLAAAARIDPKNVEIRNELKKCKEK 314
G EA L A +++P N I EL K +K
Sbjct 312 QGEFAEAIKTLKMALKLEPSNKTIHAELSKLVKK 345
> xla:447040 fkbp1a, MGC82987, fkbp10; FK506 binding protein 1A,
12kDa (EC:5.2.1.8); K01802 peptidylprolyl isomerase [EC:5.2.1.8]
Length=108
Score = 116 bits (290), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 54/106 (50%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Query 62 GVIKRVLVQGTGER-PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWD 120
GV + +G G P KG VHYVG L++G +FDSSRDR+ PF+F++G +VI+GW+
Sbjct 2 GVTLETITEGDGRTFPKKGQTAVVHYVGSLDNGKKFDSSRDRNKPFKFIIGRNEVIRGWE 61
Query 121 LGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
GVA MSVG+++ L P Y YG G G IPPN+TL F+VELL
Sbjct 62 EGVAQMSVGQRARLVCSPDYAYGATGHPGIIPPNSTLTFDVELLKL 107
> hsa:2280 FKBP1A, FKBP-12, FKBP1, FKBP12, PKC12, PKCI2, PPIASE;
FK506 binding protein 1A, 12kDa (EC:5.2.1.8); K09568 FK506-binding
protein 1 [EC:5.2.1.8]
Length=108
Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 53/91 (58%), Positives = 67/91 (73%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P +G VHY G LEDG +FDSSRDR+ PF+F+LG+ +VI+GW+ GVA MSVG+++ LT
Sbjct 17 PKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
I P Y YG G G IPP+ATL F+VELL
Sbjct 77 ISPDYAYGATGHPGIIPPHATLVFDVELLKL 107
> xla:495188 fkbp8; FK506 binding protein 8, 38kDa; K09574 FK506-binding
protein 8 [EC:5.2.1.8]
Length=408
Score = 115 bits (289), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 83/264 (31%), Positives = 134/264 (50%), Gaps = 9/264 (3%)
Query 55 VDVSGDGGVIKRVLVQGTG--ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGE 112
+DV G+G + K+VL+ G G RP KG +V V LE+ + D++S F LG+
Sbjct 90 LDVLGNGILKKKVLISGKGAESRPRKGQDVTVQLKSMLENENVVE---DQES-LTFTLGD 145
Query 113 GQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAKQ 172
G VI+ DL V M VGE S++ Y YG+ G IPPN+ L EV LL +
Sbjct 146 GDVIQALDLCVQLMEVGETSLIASDAKYCYGKEGRSPDIPPNSNLNLEVTLLDVQ-DGPD 204
Query 173 RWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSH--WSPQQQTLKL 230
+S +EK+ A ++E+GN +++ D A +Y L + SS +S ++++ L
Sbjct 205 LENLSGQEKLNLANKKRERGNFYYQQADYIFAINSYDIALNVVNSSSKVDFSSEEESSLL 264
Query 231 SVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSD 290
V++ NL+ LK + A+ + ++ +N KA +R+G A G +A +
Sbjct 265 DVKMKCLNNLAASQLKLDHYEAALKSCNMVLEHQPENIKALFRKGKVLAQQGEYSDAITI 324
Query 291 LAAAARIDPKNVEIRNELKKCKEK 314
L A +++P N I EL + +K
Sbjct 325 LRKALKLEPANKTIHAELSRLVKK 348
> cel:Y18D10A.19 fkb-2; FK506-Binding protein family member (fkb-2)
Length=108
Score = 114 bits (286), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 60/104 (57%), Positives = 72/104 (69%), Gaps = 1/104 (0%)
Query 62 GVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWD 120
GV +++LV+G +P G V HYV LE+G + DSSRDR +PF+F +G+G+VIKGWD
Sbjct 2 GVDRQILVEGDNVTKPKNGQTVTCHYVLTLENGKKIDSSRDRGTPFKFKIGKGEVIKGWD 61
Query 121 LGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELL 164
GVA MSVGEKS LTI GYG G IP NATL FEVELL
Sbjct 62 QGVAQMSVGEKSKLTISADLGYGPRGVPPQIPANATLVFEVELL 105
> dre:449552 fkbp1ab, zgc:103752; FK506 binding protein 1Ab; K01802
peptidylprolyl isomerase [EC:5.2.1.8]
Length=108
Score = 114 bits (286), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 53/91 (58%), Positives = 65/91 (71%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHYVG L DG +FDSSRDRD PF+F +G+ +VI+GW+ GV MSVG+++ LT
Sbjct 17 PKKGQTCVVHYVGSLTDGRKFDSSRDRDKPFKFKIGKQEVIRGWEEGVVQMSVGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
P + YG G G IPPNATL F+VELLS
Sbjct 77 CSPDFAYGNKGHPGIIPPNATLIFDVELLSL 107
> dre:335335 fkbp1aa, fj02g10, wu:fj02g10, zgc:73373; FK506 binding
protein 1Aa (EC:5.2.1.8); K01802 peptidylprolyl isomerase
[EC:5.2.1.8]
Length=108
Score = 111 bits (278), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 52/91 (57%), Positives = 64/91 (70%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHYVG L DG +FDSSRDR PF+F +G+ +VI+GWD GVA MSVG+++ LT
Sbjct 17 PKKGQTCVVHYVGSLTDGRKFDSSRDRGKPFKFKIGKQEVIRGWDEGVAQMSVGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
P + YG G G IPPNATL F+VEL+
Sbjct 77 CTPDFAYGSKGHPGVIPPNATLIFDVELIGL 107
> mmu:14225 Fkbp1a, 12kDa, FKBP12, FKBP12-T1, FKBP12-T2, Fkbp,
Fkbp1, mFKBP1, mFKBP12; FK506 binding protein 1a (EC:5.2.1.8);
K09568 FK506-binding protein 1 [EC:5.2.1.8]
Length=108
Score = 110 bits (275), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 51/91 (56%), Positives = 64/91 (70%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P +G VHY G LEDG +FDSSRDR+ PF+F LG+ +VI+GW+ GVA MSVG+++ L
Sbjct 17 PKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLI 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
I Y YG G G IPP+ATL F+VELL
Sbjct 77 ISSDYAYGATGHPGIIPPHATLVFDVELLKL 107
> cel:F36H1.1 fkb-1; FK506-Binding protein family member (fkb-1);
K09569 FK506-binding protein 2 [EC:5.2.1.8]
Length=139
Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 50/93 (53%), Positives = 64/93 (68%), Gaps = 0/93 (0%)
Query 74 ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSM 133
++ KG ++ +HY G L DGT+FDSSR R+ F F LG+G VIKGWD G+ M VGE+ +
Sbjct 40 QKSRKGDQLHMHYTGTLLDGTEFDSSRTRNEEFTFTLGQGNVIKGWDQGLLNMCVGERRI 99
Query 134 LTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
LTI P GYGE GA IP N+ LKF+VEL+
Sbjct 100 LTIPPHLGYGERGAPPKIPGNSVLKFDVELMKI 132
> hsa:23770 FKBP8, FKBP38, FKBPr38; FK506 binding protein 8, 38kDa
(EC:5.2.1.8); K09574 FK506-binding protein 8 [EC:5.2.1.8]
Length=413
Score = 108 bits (271), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 84/266 (31%), Positives = 130/266 (48%), Gaps = 12/266 (4%)
Query 55 VDVSGDGGVIKRVLVQGT--GERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSP-FRFVLG 111
+D+ G+G + K+ LV G RP KG V VH LE+GT R ++ P F LG
Sbjct 94 LDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGT-----RVQEEPELVFTLG 148
Query 112 EGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGT-IPPNATLKFEVELLSFRAKA 170
+ VI+ DL V M VGE +M+T Y YG G+ IPP+A L EV L +
Sbjct 149 DCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKT-AVDG 207
Query 171 KQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSH--WSPQQQTL 228
++ +E++ A ++E GNA +++ D AA +Y + + S+ + +++
Sbjct 208 PDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQ 267
Query 229 KLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEAR 288
L ++V NL+ LK + A+ S ++ N KA +R+G A G EA
Sbjct 268 LLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAI 327
Query 289 SDLAAAARIDPKNVEIRNELKKCKEK 314
L AA +++P N I EL K +K
Sbjct 328 PILRAALKLEPSNKTIHAELSKLVKK 353
> dre:393785 fkbp1b, MGC73381, zgc:73381; FK506 binding protein
1b (EC:5.2.1.8); K09568 FK506-binding protein 1 [EC:5.2.1.8]
Length=108
Score = 108 bits (270), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 49/91 (53%), Positives = 64/91 (70%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHY+G L++G +FDSSRDR+ PF+F +G +VIKGW+ GVA MS+G+++ +T
Sbjct 17 PKKGQTCVVHYIGMLQNGKKFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSLGQRAKIT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
P YG G G IPPNATL F+VELL
Sbjct 77 CTPDMAYGATGHPGVIPPNATLIFDVELLKL 107
> sce:YNL135C FPR1, FKB1, RBP1; Fpr1p (EC:5.2.1.8); K09568 FK506-binding
protein 1 [EC:5.2.1.8]
Length=114
Score = 106 bits (265), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 52/89 (58%), Positives = 63/89 (70%), Gaps = 0/89 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P G V +HY G LE+G +FDSS DR SPF+ +G GQVIKGWD+G+ +SVGEK+ LT
Sbjct 23 PKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVGEKARLT 82
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELL 164
I Y YG G G IPPN+TL F+VELL
Sbjct 83 IPGPYAYGPRGFPGLIPPNSTLVFDVELL 111
> ath:AT4G25340 immunophilin-related / FKBP-type peptidyl-prolyl
cis-trans isomerase-related; K14826 FK506-binding nuclear
protein [EC:5.2.1.8]
Length=477
Score = 105 bits (263), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 58/139 (41%), Positives = 85/139 (61%), Gaps = 3/139 (2%)
Query 31 PPAAAAAAAAAAADTSPPHAADTEVDVSGDGGVIKRV-LVQGTGERPPKGYEVEVHYVGK 89
P AA + +P + ++V +G +++ + + + G+R G V V Y+GK
Sbjct 340 PSDEAAEISGTVEKQTPADSKSSQVRTYPNGLIVEELSMGKPNGKRADPGKTVSVRYIGK 399
Query 90 LE-DGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAG 148
L+ +G FDS+ + SPF+F LG G VIKGWD+GV M VG+K LTI P+ GYG GAG
Sbjct 400 LQKNGKIFDSNIGK-SPFKFRLGIGSVIKGWDVGVNGMRVGDKRKLTIPPSMGYGVKGAG 458
Query 149 GTIPPNATLKFEVELLSFR 167
G IPPN+ L F+VEL++ +
Sbjct 459 GQIPPNSWLTFDVELINVQ 477
> dre:402839 fkbp6, im:5411885, si:dkey-189h5.5; FK506 binding
protein 6 (EC:5.2.1.8); K09572 FK506-binding protein 6 [EC:5.2.1.8]
Length=343
Score = 104 bits (260), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 74/268 (27%), Positives = 129/268 (48%), Gaps = 15/268 (5%)
Query 56 DVSGDGGVIKRVLVQGTGERPPKGYE--VEVHYVGKLE-DGTQFDSSRDRDSPFRFVLGE 112
D+ GDGGV+K V+ +G G PP V +++ G +E F+++ P LG+
Sbjct 37 DILGDGGVLKEVIHEGEG--PPVSMHASVSINFSGFIEYTDAPFETTNHLKYPRMMKLGK 94
Query 113 GQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF--RAKA 170
+ G +LG+ TM GE S +P Y YG+ G IPP AT+ +EV++L F A+
Sbjct 95 DVTLYGLELGLLTMKKGEFSRFLFKPKYAYGDLGCPPHIPPCATVLYEVQVLDFLDSAQV 154
Query 171 KQRWAMSVEEK--------IQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWS 222
+++EE+ + ++ GN F KK +A Y++ + L++
Sbjct 155 DDFMDLTLEEQNTAPLSVLLNVLDTQRSFGNLCFNKKRYEDARERYKQAMTLLQNREPED 214
Query 223 PQQQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFG 282
+++ +++ LNLS YLK + +A+ A+ ++ +N+KA +R G A
Sbjct 215 AEEKKHLEEIKLPFLLNLSFTYLKLEKPQKALLYGQKALDINPQNTKALFRCGQACLEMK 274
Query 283 LLDEARSDLAAAARIDPKNVEIRNELKK 310
++A+ L A P + +I L K
Sbjct 275 DYEKAQDYLTLAQAKKPFDPDINTLLIK 302
> mmu:14226 Fkbp1b, 12.6kDa, AW494148, FKBP12.6; FK506 binding
protein 1b (EC:5.2.1.8); K09568 FK506-binding protein 1 [EC:5.2.1.8]
Length=108
Score = 104 bits (259), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 49/91 (53%), Positives = 64/91 (70%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHY G L++G +FDSSRDR+ PF+F +G+ +VIKG++ G A MS+G+++ LT
Sbjct 17 PKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
P YG G G IPPNATL F+VELLS
Sbjct 77 CTPDVAYGATGHPGVIPPNATLIFDVELLSL 107
> hsa:2281 FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase; FK506
binding protein 1B, 12.6 kDa (EC:5.2.1.8); K09568 FK506-binding
protein 1 [EC:5.2.1.8]
Length=108
Score = 103 bits (258), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 48/91 (52%), Positives = 64/91 (70%), Gaps = 0/91 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHY G L++G +FDSSRDR+ PF+F +G+ +VIKG++ G A MS+G+++ LT
Sbjct 17 PKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
P YG G G IPPNATL F+VELL+
Sbjct 77 CTPDVAYGATGHPGVIPPNATLIFDVELLNL 107
> xla:399004 fkbp1b, MGC68829, PPIase, fkbp12.6, fkbp1l, otk4,
pkbp1l; FK506 binding protein 1B, 12.6 kDa (EC:5.2.1.8); K09568
FK506-binding protein 1 [EC:5.2.1.8]
Length=108
Score = 103 bits (258), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 49/89 (55%), Positives = 59/89 (66%), Gaps = 0/89 (0%)
Query 76 PPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLT 135
P KG VHY G L G FDSSRDR+ PF+F +G +VIKGW+ GVA MSVG+++ LT
Sbjct 17 PKKGQTCVVHYTGMLTSGKTFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSVGQRAKLT 76
Query 136 IQPTYGYGEAGAGGTIPPNATLKFEVELL 164
P YG G G IPPNA L F+VEL+
Sbjct 77 CSPDVAYGATGHPGVIPPNAVLIFDVELI 105
> ath:AT3G54010 PAS1; PAS1 (PASTICCINO 1); FK506 binding / binding
/ peptidyl-prolyl cis-trans isomerase
Length=635
Score = 103 bits (257), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 76/252 (30%), Positives = 122/252 (48%), Gaps = 11/252 (4%)
Query 56 DVSGDGGVIKRVLVQGTGERPP----KGYEVEVHYVGKL--EDGTQFDSSR--DRDSPFR 107
D+ GDG +IKR + G GE P + + VHY G L E+ T F S+ + D P
Sbjct 264 DMLGDGRLIKRRIRDGRGEFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLE 323
Query 108 FVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFR 167
F GEG V +G+++ M GE +++T P Y Y + + A +++E+ELL F
Sbjct 324 FSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRPPGVSEGAHVQWEIELLGF- 382
Query 168 AKAKQRWAMSVEEKIQAAADE-KEKGNAAFKKKDLAEAAAAYREGLAFLEHSSHWSPQQQ 226
+ + W + I AD+ + GN FK+ A A Y + L H + +
Sbjct 383 -ETPRDWTGLNFQSIMDEADKIRSTGNRLFKEGKFELAKAKYEKVLREFNHVNPQDEDEG 441
Query 227 TLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDE 286
+ L LN++ C LK GE+ ++I+ + ++ + K YRRG+A A G D+
Sbjct 442 KIFGDTRNMLHLNVAACLLKMGEWRKSIETCNKVLEAKPGHVKGLYRRGMAYIAGGEYDD 501
Query 287 ARSDLAAAARID 298
AR+D ++D
Sbjct 502 ARNDFNMMIKVD 513
Score = 55.1 bits (131), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 42/120 (35%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
Query 61 GGVIKRVLVQGTGERPP-KGYEVEVHYVGKLEDGTQFDSSRD----RDSPFRFVLGEGQV 115
G ++K V+ G G+ P G +V H + DG +S+R R P R VLG ++
Sbjct 32 GSLLKAVVRPGGGDSSPVDGDQVIYHCTVRTLDGVVVESTRSESGGRGVPIRDVLGNSKM 91
Query 116 IKGWDLGVATMSVGEKSMLTIQPTYGYGE----AGAGGTIPPNATLKFEVELLSFRAKAK 171
I G G+ TM GE +M ++P Y E A P + L FE+ELL F +KAK
Sbjct 92 ILGLLEGIPTMHKGEIAMFKMKPEMHYAEIDCPVSAPENFPKDDELHFEIELLDF-SKAK 150
Score = 50.8 bits (120), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 4/110 (3%)
Query 58 SGDGGVIKRVLVQGTG-ERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVI 116
S D GVIK++L +G G E P + YEV+ K DG S + P+ F G+ +V
Sbjct 153 SDDLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHVIFSHTE--EPYFFTFGKSEVP 210
Query 117 KGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
KG ++G+ TM+ EK+++ ++ Y E+ + FEVEL+ F
Sbjct 211 KGLEIGIGTMARKEKAVIYVRKQY-LTESPLLHIDQDLEEVHFEVELVHF 259
> ath:AT3G55520 immunophilin, putative / FKBP-type peptidyl-prolyl
cis-trans isomerase, putative
Length=190
Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 60/154 (38%), Positives = 91/154 (59%), Gaps = 12/154 (7%)
Query 55 VDVSGDGGVIKRVL-------VQGTGERPPKGYEVEVHYVGKL-EDGTQFDSSRDRDSPF 106
+D+SGDGGV+K+++ + + + P V+VHY G L ED FD++R+ + F
Sbjct 5 IDLSGDGGVLKKIVRSAKPDAISPSDDLPV----VDVHYEGILAEDEKVFDTTREDNLVF 60
Query 107 RFVLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSF 166
F LG G VI+ WD+ + TM VGE + +T +P Y YG AG+ IPP+ATL FEVEL++
Sbjct 61 SFELGTGSVIRSWDIALKTMKVGEVAKITCKPEYAYGRAGSPPDIPPDATLIFEVELVAC 120
Query 167 RAKAKQRWAMSVEEKIQAAADEKEKGNAAFKKKD 200
R + EE+ + +K++ AA K+D
Sbjct 121 RPRKGASVGSVSEERARLEDLKKQREIAAAAKED 154
> sce:YDR519W FPR2, FKB2; Fpr2p (EC:5.2.1.8); K09569 FK506-binding
protein 2 [EC:5.2.1.8]
Length=135
Score = 102 bits (255), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 57/110 (51%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
Query 62 GVIKRVLVQGTGERPPKGYEVEVHYVGKL-EDGTQFDSSRDRDSPFRFVLGEGQVIKGWD 120
G+IKR+ V+ + G +V+VHY G L E GT FDSS R SP F LG G+VIKGWD
Sbjct 26 GIIKRIPVEDCLIKAMPGDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGRVIKGWD 85
Query 121 LGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKA 170
GVA M VGEK L I + YGE G G IPP+A L F+VEL+ ++ A
Sbjct 86 QGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDVKSAA 135
> xla:379180 fkbp2, MGC130827, MGC53657; FK506 binding protein
2, 13kDa; K09569 FK506-binding protein 2 [EC:5.2.1.8]
Length=141
Score = 102 bits (254), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 57/110 (51%), Positives = 68/110 (61%), Gaps = 2/110 (1%)
Query 62 GVIKRVLVQGTGERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDL 121
GV KRV + + KG + +HY GKLEDGT+FDSS R+ PF F LG GQVIKGWD
Sbjct 33 GVKKRV--ENCPVKSRKGDTLHMHYTGKLEDGTEFDSSIPRNQPFTFTLGTGQVIKGWDQ 90
Query 122 GVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAK 171
G+ M GEK L I GYG+ GA IP ATL FEVELL +++
Sbjct 91 GLLGMCEGEKRKLVIPSELGYGDRGAPPKIPGGATLIFEVELLKIERRSE 140
> xla:443985 MGC80429 protein; K01802 peptidylprolyl isomerase
[EC:5.2.1.8]
Length=141
Score = 102 bits (253), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 56/109 (51%), Positives = 67/109 (61%), Gaps = 2/109 (1%)
Query 62 GVIKRVLVQGTGERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDL 121
GV KRV + + KG + +HY GKLEDGT+FDSS R+ PF F LG GQVIKGWD
Sbjct 33 GVKKRV--ENCPVKSRKGDTLHMHYTGKLEDGTEFDSSIPRNQPFTFTLGTGQVIKGWDQ 90
Query 122 GVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRAKA 170
G+ M GEK L I GYG+ GA IP ATL FEVEL+ ++
Sbjct 91 GLLGMCEGEKRKLVIPSELGYGDRGAPPKIPGGATLIFEVELMKIERRS 139
> mmu:14232 Fkbp8, 38kDa, FKBP-38, FKBP-8, Fkbp38; FK506 binding
protein 8 (EC:5.2.1.8); K09574 FK506-binding protein 8 [EC:5.2.1.8]
Length=403
Score = 101 bits (251), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 83/266 (31%), Positives = 129/266 (48%), Gaps = 12/266 (4%)
Query 55 VDVSGDGGVIKRVLVQGT--GERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSP-FRFVLG 111
+D+ G+G + + LV G RP KG V VH LE+GT R ++ P F LG
Sbjct 84 LDILGNGLLRMKTLVPGPKGSSRPLKGQVVTVHLQMSLENGT-----RVQEEPELAFTLG 138
Query 112 EGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGT-IPPNATLKFEVELLSFRAKA 170
+ VI+ DL V M VGE +M+T Y YG G+ IPP+A L EV L +
Sbjct 139 DCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAE-DG 197
Query 171 KQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSSH--WSPQQQTL 228
+S +E++ A ++E GNA +++ D AA +Y + + ++ + +++
Sbjct 198 PDLEMLSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCEEEEE 257
Query 229 KLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEAR 288
L ++V NL+ LK + A+ S ++ N KA +R+G A G EA
Sbjct 258 LLQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAI 317
Query 289 SDLAAAARIDPKNVEIRNELKKCKEK 314
L AA +++P N I EL K +K
Sbjct 318 PILRAALKLEPSNKTIHAELSKLVKK 343
> mmu:14227 Fkbp2, 13kDa, FKBP-2, mFKBP13, mFKBP2; FK506 binding
protein 2 (EC:5.2.1.8); K09569 FK506-binding protein 2 [EC:5.2.1.8]
Length=140
Score = 101 bits (251), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 52/94 (55%), Positives = 61/94 (64%), Gaps = 0/94 (0%)
Query 78 KGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQ 137
KG + +HY GKLEDGT+FDSS ++ PF F LG GQVIKGWD G+ M GEK L I
Sbjct 46 KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIP 105
Query 138 PTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAK 171
GYGE GA IP ATL FEVELL +++
Sbjct 106 SELGYGERGAPPKIPGGATLVFEVELLKIERRSE 139
> hsa:2286 FKBP2, FKBP-13, PPIase; FK506 binding protein 2, 13kDa
(EC:5.2.1.8); K09569 FK506-binding protein 2 [EC:5.2.1.8]
Length=142
Score = 100 bits (249), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 52/94 (55%), Positives = 60/94 (63%), Gaps = 0/94 (0%)
Query 78 KGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQ 137
KG + +HY GKLEDGT+FDSS ++ PF F LG GQVIKGWD G+ M GEK L I
Sbjct 48 KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIP 107
Query 138 PTYGYGEAGAGGTIPPNATLKFEVELLSFRAKAK 171
GYGE GA IP ATL FEVELL + +
Sbjct 108 SELGYGERGAPPKIPGGATLVFEVELLKIERRTE 141
> ath:AT5G48580 FKBP15-2; FK506 binding / peptidyl-prolyl cis-trans
isomerase; K09569 FK506-binding protein 2 [EC:5.2.1.8]
Length=163
Score = 97.1 bits (240), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 51/92 (55%), Positives = 59/92 (64%), Gaps = 0/92 (0%)
Query 78 KGYEVEVHYVGKLEDGTQFDSSRDRDSPFRFVLGEGQVIKGWDLGVATMSVGEKSMLTIQ 137
KG ++VHY GKL DGT FDSS +R PF F LG GQVIKGWD G+ VGEK L I
Sbjct 51 KGDTIKVHYRGKLTDGTVFDSSFERGDPFEFKLGSGQVIKGWDQGLLGACVGEKRKLKIP 110
Query 138 PTYGYGEAGAGGTIPPNATLKFEVELLSFRAK 169
GYGE G+ TIP ATL F+ EL++ K
Sbjct 111 AKLGYGEQGSPPTIPGGATLIFDTELIAVNEK 142
> dre:100149392 aryl hydrocarbon receptor interacting protein-like
Length=342
Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 81/292 (27%), Positives = 122/292 (41%), Gaps = 60/292 (20%)
Query 62 GVIKRVLVQGTGERP--PKGYEVEVHYVGKLEDGTQFDSSRD---RDSPFRFVLGEGQVI 116
G+ K+V+ G GE P G +V+ HY L DGT D SR P +LG+ +
Sbjct 12 GIQKKVISPGKGELSTFPNGTKVKFHYRTSLCDGTLLDDSRTMGGHSKPMELILGKKFKL 71
Query 117 KGWDLGVATMSVGEKSMLTI---------------------------------------Q 137
W+ V TM GE + T
Sbjct 72 PVWEQVVTTMKEGEIAEFTCDVKHTALYPLVSLSLRNISQGKDPLEGQRHCCGIAQVHSH 131
Query 138 PTYGYGEAGAGGTIPPNATLKFEV-ELLSFRAKAKQRWAMSVEEKIQAAADEKEKGNAAF 196
+ G+ + T P E+ ++LS + ++ WAM+ +EK+ A E+GNA F
Sbjct 132 HSLGHHDLDKLQTNPQPLIFTLELLQVLSPGSYQQEIWAMTDDEKLGAIPQIHEEGNALF 191
Query 197 KKKDLAEAAAAYREGLAFLEH--------SSHWSPQQQTLKLSVEVS-LRLNLSNCYLKT 247
K D++ AA Y +A L+ HW +KL + ++ L LN C L
Sbjct 192 KSGDISAAAEKYYNAIACLKSLQMKERPGDEHW------IKLDLMITPLLLNYCQCKLLL 245
Query 248 GEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDP 299
G++ + +D S+ I E N KA+++RG A AA EAR+D A +DP
Sbjct 246 GQYYEVLDHCSSIINKYEDNVKAYFKRGKAHAAVWNEAEARADFAKVLTLDP 297
> dre:497400 im:7140236; si:ch211-13k12.1
Length=495
Score = 95.9 bits (237), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 77/267 (28%), Positives = 126/267 (47%), Gaps = 11/267 (4%)
Query 51 ADTEVDVSGDGGVIKRVLVQG--TGERPPKGYEVEVHYVGKLEDGTQFDSSRDRDSPFRF 108
AD +++ D + K+VL G P G EV + G LED T + +DS F
Sbjct 168 ADDWKNITDDCLLKKKVLQAGPENALTPAWGQEVTLKMQGVLEDRTVVE----KDSKLVF 223
Query 109 VLGEGQVIKGWDLGVATMSVGEKSMLTIQPTYGYGEAGAGGTIPPNATLKFEVELLSFRA 168
++GEG V + + TM GE ++L Y YG G IP A L ++++LL FR
Sbjct 224 IIGEGDVTQALEECAITMKKGEIALLLADSQYTYGLLGREPDIPAWAPLLYQLQLLDFRE 283
Query 169 KAKQRWAMSVEEKIQAAADEKEKGNAAFKKKDLAEAAAAYREGLAFLEHSS----HWSPQ 224
K + V ++I+ ++E+GN F++++ ++A AY L L + + +
Sbjct 284 KPDP-LLLPVPDRIRIGNQKRERGNFYFQREEFSKAVQAYCMALDVLTTRTNDGQNCVAE 342
Query 225 QQTLKLSVEVSLRLNLSNCYLKTGEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLL 284
++ V NL+ LK G F +A+ + + LD +N KA +R+G + G
Sbjct 343 EEEEVNDYRVKCLNNLAAAQLKLGHFDEALHTSQDVLFLDPQNVKALFRKGKLLSDKGEY 402
Query 285 DEARSDLAAAARIDPKNVEIRNELKKC 311
+EA L A +++P I EL K
Sbjct 403 EEAMETLKKALKLEPSTKAIHAELSKL 429
> dre:334795 aip, MGC101101, wu:fa03h10, zgc:101101; aryl hydrocarbon
receptor interacting protein
Length=342
Score = 95.1 bits (235), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 84/292 (28%), Positives = 125/292 (42%), Gaps = 60/292 (20%)
Query 62 GVIKRVLVQGTGERP--PKGYEVEVHYVGKLEDGTQFDSSRD---RDSPFRFVLGEGQVI 116
G+ K+V+ G GE P G +V+ HY L DGT D SR P +LG+ +
Sbjct 12 GIQKKVISPGKGELSTFPNGTKVKFHYRTSLCDGTLLDDSRTMGGHSKPMELILGKKFKL 71
Query 117 KGWDLGVATMSVGEKSMLT--IQPTYGY------------------GEAGAGGTIPPNAT 156
W+ V TM GE + T ++ T Y G+ G ++
Sbjct 72 PVWEQVVTTMKEGEIAEFTCDVKHTALYPLVSLSLRNISQGKDPLEGQRHCCGIAQVHSH 131
Query 157 -----------------LKFEVELLSFRAKA---KQRWAMSVEEKIQAAADEKEKGNAAF 196
L F +ELL + ++ WAM+ +EK+ A E+GNA F
Sbjct 132 HSLGHHDLDKLQSNPQPLIFTLELLQVLSPGSYQQEIWAMTDDEKLGAIPQIHEEGNALF 191
Query 197 KKKDLAEAAAAYREGLAFLEH--------SSHWSPQQQTLKLSVEVS-LRLNLSNCYLKT 247
K D++ AA Y +A L+ HW +KL + ++ L LN C L
Sbjct 192 KSGDISGAAEKYYNAIACLKSLQMKERPGDEHW------IKLDLMITPLLLNYCQCKLLL 245
Query 248 GEFAQAIDEASAAIKLDEKNSKAWYRRGVARAAFGLLDEARSDLAAAARIDP 299
G++ + +D S+ I E N KA+++RG A AA EAR+D A +DP
Sbjct 246 GQYYEVLDHCSSIINKYEDNVKAYFKRGKAHAAVWNEAEARADFAKVLTLDP 297
Lambda K H
0.314 0.130 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 12920510708
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40