bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_3498_orf1
Length=76
Score E
Sequences producing significant alignments: (Bits) Value
cpv:cgd7_220 GTP-binding nuclear protein ran/tc4 ; K07936 GTP-... 133 1e-31
tgo:TGME49_048340 GTP-binding nuclear protein RAN/TC4, putativ... 131 5e-31
pfa:PF11_0183 ran; GTP-binding nuclear protein ran/tc4; K07936... 124 1e-28
tpv:TP01_0757 GTP-binding nuclear protein ran; K07936 GTP-bind... 122 2e-28
xla:379874 ran-1, MGC53579, ran; RAN, member RAS oncogene fami... 122 3e-28
xla:100189578 ran, ara24, gsp1, ran-1, tc4, xran; RAN, member ... 122 3e-28
bbo:BBOV_IV010920 23.m06098; GTP-binding nuclear protein Ran; ... 122 4e-28
mmu:19384 Ran; RAN, member RAS oncogene family; K07936 GTP-bin... 122 4e-28
mmu:100045999 GTP-binding nuclear protein Ran-like; K07936 GTP... 122 4e-28
hsa:5901 RAN, ARA24, Gsp1, TC4; RAN, member RAS oncogene famil... 122 4e-28
sce:YOR185C GSP2, CNR2; GTP binding protein (mammalian Ranp ho... 119 3e-27
sce:YLR293C GSP1, CNR1, CST17; Gsp1p; K07936 GTP-binding nucle... 118 4e-27
cel:K01G5.4 ran-1; associated with RAN (nuclear import/export)... 118 4e-27
dre:30572 ran, fc16b04, wu:fc16b04; ras-related nuclear protei... 117 7e-27
mmu:19428 Rasl2-9-ps, M2, Ran, Ran/M2, Rasl2-9; RAS-like, fami... 117 1e-26
mmu:75471 1700009N14Rik, AI429145; RIKEN cDNA 1700009N14 gene;... 115 4e-26
ath:AT5G55190 RAN3; RAN3 (RAN GTPASE 3); GTP binding / GTPase/... 112 2e-25
ath:AT5G20010 RAN-1; RAN-1; GTP binding / GTPase/ protein bind... 112 3e-25
ath:AT5G20020 RAN2; RAN2; GTP binding / GTPase/ protein bindin... 112 3e-25
ath:AT5G55080 AtRAN4; AtRAN4 (Ras-related nuclear protein 4); ... 97.1 1e-20
sce:YOR089C VPS21, VPS12, VPT12, YPT21, YPT51; GTPase required... 53.1 2e-07
dre:494576 zgc:110195; si:dkey-13a21.4 53.1 2e-07
dre:450074 rab34, zgc:101620; RAB34, member RAS oncogene famil... 52.0 5e-07
sce:YNL093W YPT53; GTPase, similar to Ypt51p and Ypt52p and to... 51.6 6e-07
dre:780839 rab36, zgc:158229; RAB36, member RAS oncogene famil... 51.2 8e-07
hsa:9609 RAB36; RAB36, member RAS oncogene family; K07922 Ras-... 50.8 1e-06
xla:100127302 rab36; RAB36, member RAS oncogene family; K07922... 50.4 1e-06
tgo:TGME49_049170 ras family domain-containing protein (EC:3.1... 50.1 2e-06
mmu:68708 Rabl2, 1110031N17Rik, AW549303, Rabl2a; RAB, member ... 50.1 2e-06
mmu:76877 Rab36, 6330593L16Rik, AW047545; RAB36, member RAS on... 50.1 2e-06
pfa:PF08_0110 rab18; PfRab18, GTPase; K07910 Ras-related prote... 50.1 2e-06
hsa:11159 RABL2A, FLJ78724, MGC117180; RAB, member of RAS onco... 49.7 2e-06
pfa:PF11_0461 rab6; PfRab6, GTPase; K07976 Rab family, other 49.7 3e-06
hsa:11158 RABL2B, FLJ93981, FLJ98216; RAB, member of RAS oncog... 49.3 3e-06
tgo:TGME49_058130 Ras family domain-containing protein (EC:3.1... 48.9 4e-06
mmu:19335 Rab23, AW545388, opb, opb2; RAB23, member RAS oncoge... 48.9 4e-06
xla:446683 rabl2b, MGC83481; RAB, member of RAS oncogene famil... 48.9 4e-06
ath:AT5G03530 RABC2A; RABC2A (RAB GTPASE HOMOLOG C2A); GTP bin... 48.9 4e-06
xla:444746 MGC84778 protein 48.5 5e-06
hsa:51715 RAB23, DKFZp781H0695, HSPC137, MGC8900; RAB23, membe... 48.5 5e-06
cel:Y92C3B.3 rab-18; RAB family member (rab-18); K07910 Ras-re... 48.5 5e-06
bbo:BBOV_III000780 17.m07097; Rab1b 48.5 5e-06
tgo:TGME49_113190 Ras family domain-containing protein (EC:3.1... 48.5 5e-06
mmu:19331 Rab19; RAB19, member RAS oncogene family 48.1 7e-06
dre:100007678 Ras-related protein RAB34-like 48.1 7e-06
dre:561568 rabl2, si:dkeyp-1h4.2; RAB, member of RAS oncogene ... 48.1 7e-06
mmu:19376 Rab34, AI326479, Rah, Rah1; RAB34, member of RAS onc... 48.1 7e-06
ath:AT1G43890 ATRAB18 (ARABIDOPSIS RAB GTPASE HOMOLOG B18); GT... 48.1 7e-06
dre:100333836 RAB26, member RAS oncogene family-like 48.1 8e-06
dre:553778 rab23, MGC110261, zgc:110261; RAB23, member RAS onc... 47.8 8e-06
> cpv:cgd7_220 GTP-binding nuclear protein ran/tc4 ; K07936 GTP-binding
nuclear protein Ran
Length=212
Score = 133 bits (334), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 57/66 (86%), Positives = 65/66 (98%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKYIPT+GVEV PL+F+T+FGP++FNVWDTAGQEKFGGLRDGYYIKGQCAI+MFDV
Sbjct 30 GEFEKKYIPTIGVEVHPLKFNTDFGPLIFNVWDTAGQEKFGGLRDGYYIKGQCAIIMFDV 89
Query 71 TSRVTY 76
TSR+TY
Sbjct 90 TSRITY 95
> tgo:TGME49_048340 GTP-binding nuclear protein RAN/TC4, putative
(EC:3.1.4.12); K07936 GTP-binding nuclear protein Ran
Length=216
Score = 131 bits (329), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 59/67 (88%), Positives = 62/67 (92%), Gaps = 0/67 (0%)
Query 10 AGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 69
GEFEKKYIPTLGVEV PL+F TNFG I FNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD
Sbjct 33 TGEFEKKYIPTLGVEVHPLKFQTNFGMITFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 92
Query 70 VTSRVTY 76
VT+R+TY
Sbjct 93 VTARITY 99
> pfa:PF11_0183 ran; GTP-binding nuclear protein ran/tc4; K07936
GTP-binding nuclear protein Ran
Length=214
Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 55/67 (82%), Positives = 59/67 (88%), Gaps = 0/67 (0%)
Query 10 AGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 69
GEFEKKYIPTLGVEV PL+F TNFG FNVWDTAGQEKFGGLRDGYYIK CAI+MFD
Sbjct 31 TGEFEKKYIPTLGVEVHPLKFQTNFGKTQFNVWDTAGQEKFGGLRDGYYIKSDCAIIMFD 90
Query 70 VTSRVTY 76
V+SR+TY
Sbjct 91 VSSRITY 97
> tpv:TP01_0757 GTP-binding nuclear protein ran; K07936 GTP-binding
nuclear protein Ran
Length=211
Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 54/66 (81%), Positives = 60/66 (90%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKYIPTLGVEV PL+F TN G + FN WDTAGQEK+GGLRDGYYIKG+CAI+MFDV
Sbjct 30 GEFEKKYIPTLGVEVHPLKFRTNCGTVQFNAWDTAGQEKYGGLRDGYYIKGECAIIMFDV 89
Query 71 TSRVTY 76
TSR+TY
Sbjct 90 TSRITY 95
> xla:379874 ran-1, MGC53579, ran; RAN, member RAS oncogene family;
K07936 GTP-binding nuclear protein Ran
Length=216
Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 56/66 (84%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> xla:100189578 ran, ara24, gsp1, ran-1, tc4, xran; RAN, member
RAS oncogene family; K07936 GTP-binding nuclear protein Ran
Length=216
Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 56/66 (84%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> bbo:BBOV_IV010920 23.m06098; GTP-binding nuclear protein Ran;
K07936 GTP-binding nuclear protein Ran
Length=211
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 55/66 (83%), Positives = 60/66 (90%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKYIPTLGVEV PL+F TN G I FN WDTAGQEK+GGLRDGYYIKG+CAI+MFDV
Sbjct 30 GEFEKKYIPTLGVEVHPLKFRTNCGGIQFNAWDTAGQEKYGGLRDGYYIKGECAIIMFDV 89
Query 71 TSRVTY 76
TSR+TY
Sbjct 90 TSRITY 95
> mmu:19384 Ran; RAN, member RAS oncogene family; K07936 GTP-binding
nuclear protein Ran
Length=216
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 56/66 (84%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> mmu:100045999 GTP-binding nuclear protein Ran-like; K07936 GTP-binding
nuclear protein Ran
Length=216
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 56/66 (84%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> hsa:5901 RAN, ARA24, Gsp1, TC4; RAN, member RAS oncogene family;
K07936 GTP-binding nuclear protein Ran
Length=216
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 56/66 (84%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> sce:YOR185C GSP2, CNR2; GTP binding protein (mammalian Ranp
homolog) involved in the maintenance of nuclear organization,
RNA processing and transport; interacts with Kap121p, Kap123p
and Pdr6p (karyophilin betas); Gsp1p homolog that is not
required for viability; K07936 GTP-binding nuclear protein
Ran
Length=220
Score = 119 bits (297), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 54/66 (81%), Positives = 58/66 (87%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKYI T+GVEV PL F TNFG I F+VWDTAGQEKFGGLRDGYYI QCAI+MFDV
Sbjct 36 GEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDV 95
Query 71 TSRVTY 76
TSR+TY
Sbjct 96 TSRITY 101
> sce:YLR293C GSP1, CNR1, CST17; Gsp1p; K07936 GTP-binding nuclear
protein Ran
Length=219
Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 54/66 (81%), Positives = 58/66 (87%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKYI T+GVEV PL F TNFG I F+VWDTAGQEKFGGLRDGYYI QCAI+MFDV
Sbjct 35 GEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDV 94
Query 71 TSRVTY 76
TSR+TY
Sbjct 95 TSRITY 100
> cel:K01G5.4 ran-1; associated with RAN (nuclear import/export)
function family member (ran-1); K07936 GTP-binding nuclear
protein Ran
Length=215
Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 55/66 (83%), Positives = 59/66 (89%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN G I FNVWDTAGQEKFGGLRDGYYI+GQCAI+MFDV
Sbjct 32 GEFEKKYVATLGVEVHPLVFHTNRGQIRFNVWDTAGQEKFGGLRDGYYIQGQCAIIMFDV 91
Query 71 TSRVTY 76
T+RVTY
Sbjct 92 TARVTY 97
> dre:30572 ran, fc16b04, wu:fc16b04; ras-related nuclear protein;
K07936 GTP-binding nuclear protein Ran
Length=215
Score = 117 bits (294), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 54/66 (81%), Positives = 58/66 (87%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F TN G I +NVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 32 GEFEKKYVATLGVEVHPLVFHTNRGAIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 91
Query 71 TSRVTY 76
TSRVTY
Sbjct 92 TSRVTY 97
> mmu:19428 Rasl2-9-ps, M2, Ran, Ran/M2, Rasl2-9; RAS-like, family
2, locus 9, pseudogene; K07936 GTP-binding nuclear protein
Ran
Length=216
Score = 117 bits (292), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 54/66 (81%), Positives = 58/66 (87%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEK+Y+ TLGVEV L F TN GPI FNVWDTAGQEKFGGLRDGYYI+ QCAI+MFDV
Sbjct 33 GEFEKEYVATLGVEVHTLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDV 92
Query 71 TSRVTY 76
TSRVTY
Sbjct 93 TSRVTY 98
> mmu:75471 1700009N14Rik, AI429145; RIKEN cDNA 1700009N14 gene;
K07936 GTP-binding nuclear protein Ran
Length=216
Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 53/66 (80%), Positives = 58/66 (87%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY+ TLGVEV PL F T+ GPI FNVWDTAGQEKFGGLRDGYYI+ Q AI+MFDV
Sbjct 33 GEFEKKYVATLGVEVHPLMFHTSRGPIKFNVWDTAGQEKFGGLRDGYYIQAQGAIIMFDV 92
Query 71 TSRVTY 76
TSR+TY
Sbjct 93 TSRITY 98
> ath:AT5G55190 RAN3; RAN3 (RAN GTPASE 3); GTP binding / GTPase/
protein binding; K07936 GTP-binding nuclear protein Ran
Length=221
Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 52/66 (78%), Positives = 56/66 (84%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY PT+GVEV PL F TN G I F WDTAGQEKFGGLRDGYYI GQCAI+MFDV
Sbjct 36 GEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDV 95
Query 71 TSRVTY 76
T+R+TY
Sbjct 96 TARLTY 101
> ath:AT5G20010 RAN-1; RAN-1; GTP binding / GTPase/ protein binding;
K07936 GTP-binding nuclear protein Ran
Length=221
Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 52/66 (78%), Positives = 56/66 (84%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY PT+GVEV PL F TN G I F WDTAGQEKFGGLRDGYYI GQCAI+MFDV
Sbjct 36 GEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDV 95
Query 71 TSRVTY 76
T+R+TY
Sbjct 96 TARLTY 101
> ath:AT5G20020 RAN2; RAN2; GTP binding / GTPase/ protein binding;
K07936 GTP-binding nuclear protein Ran
Length=221
Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 52/66 (78%), Positives = 56/66 (84%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
GEFEKKY PT+GVEV PL F TN G I F WDTAGQEKFGGLRDGYYI GQCAI+MFDV
Sbjct 36 GEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDV 95
Query 71 TSRVTY 76
T+R+TY
Sbjct 96 TARLTY 101
> ath:AT5G55080 AtRAN4; AtRAN4 (Ras-related nuclear protein 4);
GTP binding / GTPase/ protein binding; K07936 GTP-binding
nuclear protein Ran
Length=222
Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 44/67 (65%), Positives = 50/67 (74%), Gaps = 0/67 (0%)
Query 10 AGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 69
GEFE PTLGV++ PL F TN G I F WDTAGQEK+ GL+D YYI GQCAI+MFD
Sbjct 35 TGEFEHNTEPTLGVDIYPLDFFTNRGKIRFECWDTAGQEKYSGLKDAYYIHGQCAIIMFD 94
Query 70 VTSRVTY 76
VT+R TY
Sbjct 95 VTARHTY 101
> sce:YOR089C VPS21, VPS12, VPT12, YPT21, YPT51; GTPase required
for transport during endocytosis and for correct sorting
of vacuolar hydrolases; localized in endocytic intermediates;
detected in mitochondria; geranylgeranylation required for
membrane association; mammalian Rab5 homolog; K07976 Rab family,
other
Length=210
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 0/62 (0%)
Query 10 AGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 69
+ +F + PT+G R + N + F +WDTAGQE+F L YY Q A++++D
Sbjct 29 SNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYD 88
Query 70 VT 71
VT
Sbjct 89 VT 90
> dre:494576 zgc:110195; si:dkey-13a21.4
Length=205
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F Y T+GV+ + + P++ +WDTAG E+F L Y C +++FDVTS
Sbjct 33 FTNLYRATIGVDFLTKEITVDRRPVILQIWDTAGTERFHSLGSSLYRGAHCCLLVFDVTS 92
Query 73 RVTY 76
V++
Sbjct 93 SVSF 96
> dre:450074 rab34, zgc:101620; RAB34, member RAS oncogene family;
K07921 Ras-related protein Rab-34
Length=260
Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats.
Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 0/59 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVT 71
F+K Y T+GV+ RF P +WDTAGQE+F + YY Q I++FD+T
Sbjct 78 FDKNYKATIGVDFEMERFEVLGVPFSLQLWDTAGQERFKCIASTYYRGAQAVIIVFDLT 136
> sce:YNL093W YPT53; GTPase, similar to Ypt51p and Ypt52p and
to mammalian rab5; required for vacuolar protein sorting and
endocytosis; K07976 Rab family, other
Length=220
Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 0/67 (0%)
Query 10 AGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFD 69
+ +F++ PT+G R + + I F +WDTAGQE+F L YY Q A+++FD
Sbjct 34 SDDFKESKEPTIGAAFLTKRITRDGKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFD 93
Query 70 VTSRVTY 76
VT+ ++
Sbjct 94 VTNEGSF 100
> dre:780839 rab36, zgc:158229; RAB36, member RAS oncogene family;
K07922 Ras-related protein Rab-36
Length=262
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 24/58 (41%), Positives = 32/58 (55%), Gaps = 0/58 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
FE+ Y T+GV+ RF + P +WDTAGQEKF + YY Q I +FD+
Sbjct 80 FERDYKATIGVDFEIERFEMSGLPFSLQIWDTAGQEKFKCIASAYYRGAQVIITVFDM 137
> hsa:9609 RAB36; RAB36, member RAS oncogene family; K07922 Ras-related
protein Rab-36
Length=333
Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats.
Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 0/59 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVT 71
F++ Y T+GV+ RF P +WDTAGQEKF + YY Q I FD+T
Sbjct 148 FDRDYKATIGVDFEIERFEIAGIPYSLQIWDTAGQEKFKCIASAYYRGAQVIITAFDLT 206
> xla:100127302 rab36; RAB36, member RAS oncogene family; K07922
Ras-related protein Rab-36
Length=242
Score = 50.4 bits (119), Expect = 1e-06, Method: Composition-based stats.
Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 0/58 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
F++ Y T+GV+ RF P F +WDTAGQEKF + YY Q I FD+
Sbjct 57 FDRDYKATIGVDFEIERFEILGIPFNFQIWDTAGQEKFKCIASAYYRGAQVIITAFDL 114
> tgo:TGME49_049170 ras family domain-containing protein (EC:3.1.4.12)
Length=771
Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 0/65 (0%)
Query 12 EFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVT 71
++ ++ T+GV+ + + +WDTAGQE+F G+ YY C I++FD+T
Sbjct 517 QYSAFHVSTIGVDFKSVLTMVKGKVCTLQLWDTAGQERFSGVTGNYYRNADCFILVFDMT 576
Query 72 SRVTY 76
R ++
Sbjct 577 RRSSF 581
> mmu:68708 Rabl2, 1110031N17Rik, AW549303, Rabl2a; RAB, member
of RAS oncogene family-like 2
Length=223
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F+ + + T + + + + I+ + WDTAGQE+F + YY K IM+FDV
Sbjct 46 FQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQR 105
Query 73 RVTY 76
++TY
Sbjct 106 KITY 109
> mmu:76877 Rab36, 6330593L16Rik, AW047545; RAB36, member RAS
oncogene family; K07922 Ras-related protein Rab-36
Length=267
Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/59 (40%), Positives = 30/59 (50%), Gaps = 0/59 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVT 71
F+ Y T+GV+ RF P +WDTAGQEKF + YY Q I FD+T
Sbjct 82 FDHDYKATIGVDFEIERFEIAGIPYSLQIWDTAGQEKFKCIASAYYRGAQVIITAFDLT 140
> pfa:PF08_0110 rab18; PfRab18, GTPase; K07910 Ras-related protein
Rab-18
Length=201
Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 0/66 (0%)
Query 11 GEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
+FE+K + T+G++ + + I +WDTAGQE+F L YY I+++D
Sbjct 33 NQFEEKVLSTIGIDFKVKYLKIDNKTIKVGIWDTAGQERFRTLTSAYYRNAHAIILVYDC 92
Query 71 TSRVTY 76
T R ++
Sbjct 93 TVRESF 98
> hsa:11159 RABL2A, FLJ78724, MGC117180; RAB, member of RAS oncogene
family-like 2A; K07931 Rab-like protein 2A
Length=228
Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F+ + + T + + + + I+ + WDTAGQE+F + YY K IM+FD+
Sbjct 46 FQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQR 105
Query 73 RVTY 76
+VTY
Sbjct 106 KVTY 109
> pfa:PF11_0461 rab6; PfRab6, GTPase; K07976 Rab family, other
Length=207
Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F+ Y T+G++ + GP+ +WDTAGQE+F L Y AI+++D+T+
Sbjct 36 FDNNYQSTIGIDFLSKTLYLDEGPVRLQLWDTAGQERFRSLIPSYIRDSAAAIVVYDITN 95
Query 73 RVTY 76
R ++
Sbjct 96 RQSF 99
> hsa:11158 RABL2B, FLJ93981, FLJ98216; RAB, member of RAS oncogene
family-like 2B; K07932 Rab-like protein 2B
Length=229
Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 0/40 (0%)
Query 37 IVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTSRVTY 76
I+ + WDTAGQE+F + YY K IM+FDV +VTY
Sbjct 70 ILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKVTY 109
> tgo:TGME49_058130 Ras family domain-containing protein (EC:3.1.4.12)
Length=238
Score = 48.9 bits (115), Expect = 4e-06, Method: Composition-based stats.
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F + YI T+GV+ R + + + +WDTAGQE+F + YY ++++DVT
Sbjct 59 FTESYITTIGVDFRFRTINVDNEIVKLQIWDTAGQERFRTITSAYYRGADGIVLVYDVTD 118
Query 73 RVTY 76
R ++
Sbjct 119 RESF 122
> mmu:19335 Rab23, AW545388, opb, opb2; RAB23, member RAS oncogene
family; K06234 Ras-related protein Rab-23
Length=237
Score = 48.9 bits (115), Expect = 4e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 0/74 (0%)
Query 3 SRVEAVRAGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQ 62
S ++ G F K Y T+GV+ + N + +WDTAGQE+F + YY Q
Sbjct 24 SMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQ 83
Query 63 CAIMMFDVTSRVTY 76
+++F T R ++
Sbjct 84 ACVLVFSTTDRESF 97
> xla:446683 rabl2b, MGC83481; RAB, member of RAS oncogene family-like
2B
Length=225
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F + + T + + + ++ + WDTAGQE+F + YY K IM+FDV
Sbjct 46 FRPQQLSTFALTLYKYSTCIDGNTVLVDFWDTAGQERFHSMHASYYHKAHACIMVFDVQR 105
Query 73 RVTY 76
++TY
Sbjct 106 KITY 109
> ath:AT5G03530 RABC2A; RABC2A (RAB GTPASE HOMOLOG C2A); GTP binding
/ GTP-dependent protein binding / myosin XI tail binding;
K07976 Rab family, other
Length=210
Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 0/58 (0%)
Query 19 PTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTSRVTY 76
PT+GV+ + + + + +WDTAGQE+F L YY Q I+++DVT R T+
Sbjct 43 PTIGVDFKIKQLTVGGKRLKLTIWDTAGQERFRTLTSSYYRGAQGIILVYDVTRRETF 100
> xla:444746 MGC84778 protein
Length=225
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F + + T + + + ++ + WDTAGQE+F + YY K IM+FDV
Sbjct 46 FRPQQLSTFALTLYKYSTCIDGNTVLVDFWDTAGQERFHSMHASYYHKAHACIMVFDVQR 105
Query 73 RVTY 76
++TY
Sbjct 106 KITY 109
> hsa:51715 RAB23, DKFZp781H0695, HSPC137, MGC8900; RAB23, member
RAS oncogene family; K06234 Ras-related protein Rab-23
Length=237
Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 0/74 (0%)
Query 3 SRVEAVRAGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQ 62
S ++ G F K Y T+GV+ + N + +WDTAGQE+F + YY Q
Sbjct 24 SMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQ 83
Query 63 CAIMMFDVTSRVTY 76
+++F T R ++
Sbjct 84 ACVLVFSTTDRESF 97
> cel:Y92C3B.3 rab-18; RAB family member (rab-18); K07910 Ras-related
protein Rab-18
Length=203
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F+ + T+GV+ R + + + +WDTAGQE+F L YY Q I ++DVTS
Sbjct 36 FDPEQAATIGVDFRVTSMAIDGNRVKLAIWDTAGQERFRTLTPSYYRGAQGVICVYDVTS 95
Query 73 RVTY 76
R ++
Sbjct 96 RSSF 99
> bbo:BBOV_III000780 17.m07097; Rab1b
Length=221
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
+ + Y+ T+GV+ + + I +WDTAGQE+F + YY I ++DVTS
Sbjct 32 YSESYMSTIGVDFKIKTVKIDNVTIKLQIWDTAGQERFRTITSTYYRGAHGIITVYDVTS 91
Query 73 RVTY 76
RV++
Sbjct 92 RVSF 95
> tgo:TGME49_113190 Ras family domain-containing protein (EC:3.1.4.12);
K07910 Ras-related protein Rab-18
Length=212
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 0/64 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F +K + T+GV+ + + + +WDTAGQE+F L YY Q IM++DV++
Sbjct 39 FNEKQLSTIGVDFKVKAMTVGDMRLKLAIWDTAGQERFRTLTSSYYRGAQGIIMVYDVSN 98
Query 73 RVTY 76
R ++
Sbjct 99 RQSF 102
> mmu:19331 Rab19; RAB19, member RAS oncogene family
Length=217
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 0/72 (0%)
Query 5 VEAVRAGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCA 64
V+ ++G + + T+GV+ + + VWDTAGQE+F + YY A
Sbjct 34 VQHFKSGVYSESQQNTIGVDFTVRSLEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAA 93
Query 65 IMMFDVTSRVTY 76
I+ +D+T R T+
Sbjct 94 IIAYDLTRRSTF 105
> dre:100007678 Ras-related protein RAB34-like
Length=215
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 0/60 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTS 72
F++ Y T+GV+ RF P +WDTAGQE+F + YY Q I++FD+++
Sbjct 36 FDRTYKATIGVDFEMERFEVLGVPFSLQLWDTAGQERFRCIASTYYRGAQAIIVVFDLSN 95
> dre:561568 rabl2, si:dkeyp-1h4.2; RAB, member of RAS oncogene
family-like 2
Length=219
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 12/63 (19%)
Query 26 RPLRFST------------NFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTSR 73
RP + ST N I+ + WDTAGQE+F + YY K +M+FDV +
Sbjct 45 RPQQLSTYALTLYKYTTTINGQTILVDFWDTAGQERFRSMHPSYYHKSHACVMVFDVQRK 104
Query 74 VTY 76
+TY
Sbjct 105 ITY 107
> mmu:19376 Rab34, AI326479, Rah, Rah1; RAB34, member of RAS oncogene
family; K07921 Ras-related protein Rab-34
Length=259
Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats.
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 0/58 (0%)
Query 13 FEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDV 70
F+K Y T+GV+ RF P +WDTAGQE+F + YY Q I++F++
Sbjct 77 FDKNYKATIGVDFEMERFEVLGVPFSLQLWDTAGQERFKCIASTYYRGAQAIIIVFNL 134
> ath:AT1G43890 ATRAB18 (ARABIDOPSIS RAB GTPASE HOMOLOG B18);
GTP binding; K07910 Ras-related protein Rab-18
Length=212
Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 0/58 (0%)
Query 19 PTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTSRVTY 76
PT+GV+ + + + +WDTAGQE+F L YY Q IM++DVT R T+
Sbjct 43 PTIGVDFKVKYLTIGEKKLKLAIWDTAGQERFRTLTSSYYRGAQGIIMVYDVTRRDTF 100
> dre:100333836 RAB26, member RAS oncogene family-like
Length=148
Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 0/60 (0%)
Query 17 YIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQCAIMMFDVTSRVTY 76
+I T+G++ R S + + +WDTAGQE+F + YY ++++DVT++ ++
Sbjct 85 FISTVGIDFRNKVLSIDSMRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKSSF 144
> dre:553778 rab23, MGC110261, zgc:110261; RAB23, member RAS oncogene
family; K06234 Ras-related protein Rab-23
Length=237
Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 0/74 (0%)
Query 3 SRVEAVRAGEFEKKYIPTLGVEVRPLRFSTNFGPIVFNVWDTAGQEKFGGLRDGYYIKGQ 62
S ++ G F K Y T+GV+ + N + +WDTAGQE+F + YY Q
Sbjct 24 SMIQRYCKGIFTKDYKKTIGVDFLERQIIVNGEDVRLMLWDTAGQEEFDAITKAYYRGAQ 83
Query 63 CAIMMFDVTSRVTY 76
+++F T R ++
Sbjct 84 ACVLVFSTTDRESF 97
Lambda K H
0.325 0.142 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2076916240
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40