bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_3670_orf2
Length=172
Score E
Sequences producing significant alignments: (Bits) Value
cpv:cgd5_3330 hypothetical protein ; K13989 Derlin-2/3 194 8e-50
tpv:TP02_0121 hypothetical protein; K13989 Derlin-2/3 179 3e-45
pfa:PF14_0653 derlin-2, putative; K13989 Derlin-2/3 174 9e-44
tgo:TGME49_017160 hypothetical protein 165 6e-41
hsa:51009 DERL2, F-LAN-1, F-LANa, FLANa; Der1-like domain fami... 106 4e-23
mmu:116891 Derl2, BC005682, CGI-101, Derlin-2, F-lana, Flana, ... 106 4e-23
dre:554093 derl2, zgc:110436; Der1-like domain family, member ... 103 4e-22
dre:393877 derl3, MGC63991, zgc:63991; Der1-like domain family... 102 9e-22
ath:AT4G21810 DER2.1; DER2.1 (DERLIN-2.1) 95.1 1e-19
ath:AT4G04860 DER2.2; DER2.2 (DERLIN-2.2); K13989 Derlin-2/3 94.4 2e-19
hsa:91319 DERL3, C22orf14, IZP6, LLN2, MGC71803, derlin-3; Der... 88.6 9e-18
mmu:70377 Derl3, 1810006I20Rik, 1810063P04Rik, IZP6, MGC118672... 83.2 4e-16
cel:R151.6 hypothetical protein; K13989 Derlin-2/3 79.3 5e-15
ath:AT4G29330 DER1; DER1 (DERLIN-1); K13989 Derlin-2/3 69.3 5e-12
cpv:cgd6_3580 hypothetical protein ; K13989 Derlin-2/3 61.6 1e-09
tpv:TP04_0764 hypothetical protein 61.6 1e-09
tgo:TGME49_094290 der1-like family domain-containing protein, ... 56.2 5e-08
cel:F25D7.1 cup-2; Coelomocyte UPtake defective family member ... 53.9 2e-07
pfa:PF10_0317 DER1-like protein, putative; K13989 Derlin-2/3 52.8 5e-07
sce:YDR411C DFM1; Dfm1p; K13989 Derlin-2/3 51.6 1e-06
bbo:BBOV_III010270 17.m07890; hypothetical protein 50.1 3e-06
bbo:BBOV_III008600 17.m10680; Der1-like family protein; K13989... 46.6 4e-05
sce:YBR201W DER1; Der1p; K13989 Derlin-2/3 44.7 2e-04
dre:406753 derl1, wu:fb09d07, wu:fb94d05, wu:fj92g12, zgc:5563... 41.2 0.002
hsa:79139 DERL1, DER-1, DER1, FLJ13784, FLJ42092, MGC3067, PRO... 39.7 0.004
mmu:67819 Derl1, 1110021N07Rik, AI195141, AW551338, Derlin-1; ... 37.7 0.017
bbo:BBOV_IV000300 21.m03031; Der1-like family 36.2 0.054
eco:b2167 fruA, ECK2160, JW2154, ptsF; fused fructose-specific... 32.7 0.66
pfa:PF14_0498 DER1; Degradation in the ER (DER1) like protein,... 30.8 2.6
pfa:MAL8P1.151 inositol phosphatase, putative 30.0 4.4
> cpv:cgd5_3330 hypothetical protein ; K13989 Derlin-2/3
Length=210
Score = 194 bits (494), Expect = 8e-50, Method: Compositional matrix adjust.
Identities = 97/162 (59%), Positives = 121/162 (74%), Gaps = 4/162 (2%)
Query 13 LFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTF 72
L + +IPPVT+V ST+LM LCTL+IISPF+LY+NW LV Q+WRL TCF FFGTF
Sbjct 2 LVVNNIPPVTKVYFAISTLLMVLCTLDIISPFNLYLNWLLVINEYQIWRLATCFFFFGTF 61
Query 73 SLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMI 129
SLHFFWN YVL++YC++LE+ H R A FLWMLI +LL SY FG + Y FSG++I
Sbjct 62 SLHFFWNAYVLLYYCASLEDVVFHSRPADFLWMLITCSWMLLLLSYFFG-AGYLFSGAVI 120
Query 130 NVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGGWN 171
NVMTYIWGRRNP+ R+S+F V APYLP++L + L+ GW
Sbjct 121 NVMTYIWGRRNPSARMSVFIFTVRAPYLPWVLMGMGLVIGWR 162
> tpv:TP02_0121 hypothetical protein; K13989 Derlin-2/3
Length=209
Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 89/163 (54%), Positives = 121/163 (74%), Gaps = 5/163 (3%)
Query 11 VDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFG 70
+D + IP +TR+ L S LM LC+L+IISP +LYM+W LVF +VWRLITCF++FG
Sbjct 1 MDSLIGPIPFMTRIYLSTSVFLMILCSLDIISPLNLYMSWTLVF-QGEVWRLITCFVYFG 59
Query 71 TFSLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGS 127
+F + FFWN+YVLI YCS+LE H + A FLWMLIC G +LLA + IFG S F+ G+
Sbjct 60 SFGMIFFWNIYVLIHYCSSLESVTMHNKPADFLWMLICNGAMLLALAQIFG-HSMFYGGT 118
Query 128 MINVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGGW 170
MIN++TYIWGR+NP +R+ I F+ V APYLP++LA++S + +
Sbjct 119 MINILTYIWGRKNPYSRVGIIFLSVPAPYLPWILAILSYMADY 161
> pfa:PF14_0653 derlin-2, putative; K13989 Derlin-2/3
Length=214
Score = 174 bits (442), Expect = 9e-44, Method: Compositional matrix adjust.
Identities = 89/167 (53%), Positives = 118/167 (70%), Gaps = 4/167 (2%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFL 67
M Q+ L ++P +TR+ L+ S LM LC+L+IISP SLY+NW LV Q WRLITCFL
Sbjct 1 MVQLSDVLGNVPLITRLYLILSFALMVLCSLDIISPLSLYLNWNLVLREHQYWRLITCFL 60
Query 68 FFGTFSLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFF 124
+FG+F +HFFW+VYVLI+YCS+LEE SA FLWM+I + +LL SY+FG YF+
Sbjct 61 YFGSFGIHFFWDVYVLIYYCSSLEEVTFRNNSADFLWMIILSCCMLLGVSYMFG-GVYFY 119
Query 125 SGSMINVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGGWN 171
S +INV+TYIW + N TRL+I F + A YLP+ L L+SL+ +N
Sbjct 120 SSCIINVITYIWSKNNSTTRLTILFFTIRASYLPWALTLLSLIVDYN 166
> tgo:TGME49_017160 hypothetical protein
Length=327
Score = 165 bits (418), Expect = 6e-41, Method: Compositional matrix adjust.
Identities = 79/109 (72%), Positives = 90/109 (82%), Gaps = 0/109 (0%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFL 67
M QVDLF +H+PPVTR L ST LM LCTLEI+SPFSLY+N+ LV QVWR+ +CFL
Sbjct 1 MAQVDLFFSHLPPVTRFYLFCSTALMLLCTLEIVSPFSLYINYNLVLQRGQVWRIFSCFL 60
Query 68 FFGTFSLHFFWNVYVLIFYCSTLEEHRRSATFLWMLICTGGLLLAFSYI 116
FFGTFSLHFFWNVYVLIFYC+TLEEH+RSATFLWML+ TG LLL Y+
Sbjct 61 FFGTFSLHFFWNVYVLIFYCATLEEHQRSATFLWMLLTTGALLLIPPYL 109
> hsa:51009 DERL2, F-LAN-1, F-LANa, FLANa; Der1-like domain family,
member 2; K13989 Derlin-2/3
Length=239
Score = 106 bits (264), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 64/157 (40%), Positives = 89/157 (56%), Gaps = 6/157 (3%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
IPPV+R A + A LE+I+PF LY N +L+F H Q+WRLIT FLFFG +F
Sbjct 12 QIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNF 71
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINVMT 133
+N+ L YC LEE R+A F++M + G L+ F VS F + ++
Sbjct 72 LFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLF--VSLVFLGQAFTIMLV 129
Query 134 YIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
Y+W RRNP R++ F + AP+LP++L SLL G
Sbjct 130 YVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLG 166
> mmu:116891 Derl2, BC005682, CGI-101, Derlin-2, F-lana, Flana,
MGC11613, RP23-83I13.8; Der1-like domain family, member 2;
K13989 Derlin-2/3
Length=239
Score = 106 bits (264), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 64/157 (40%), Positives = 89/157 (56%), Gaps = 6/157 (3%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
IPPV+R A + A LE+I+PF LY N +L+F H Q+WRLIT FLFFG +F
Sbjct 12 QIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNF 71
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINVMT 133
+N+ L YC LEE R+A F++M + G L+ F VS F + ++
Sbjct 72 LFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLF--VSLVFLGQAFTIMLV 129
Query 134 YIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
Y+W RRNP R++ F + AP+LP++L SLL G
Sbjct 130 YVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLG 166
> dre:554093 derl2, zgc:110436; Der1-like domain family, member
2; K13989 Derlin-2/3
Length=239
Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 68/159 (42%), Positives = 91/159 (57%), Gaps = 10/159 (6%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
IP VTR A + A LE+I+PF LY N L+ + QVWRLIT FLFFG +F
Sbjct 12 QIPVVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILRNYQVWRLITNFLFFGPVGFNF 71
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFG--VSSYFFSGSMINV 131
+N+ L YC LEE R+A F++M + GGLL+ IFG V+ F + +
Sbjct 72 LFNMIFLYRYCRMLEEGSFRGRTADFVFMFLF-GGLLMT---IFGTFVNLVFLGQAFTIM 127
Query 132 MTYIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
+ YIW RRNPN R++ F + AP+LP++L SLL G
Sbjct 128 LVYIWSRRNPNVRMNFFGLLNFQAPFLPWVLMGFSLLLG 166
> dre:393877 derl3, MGC63991, zgc:63991; Der1-like domain family,
member 3; K13989 Derlin-2/3
Length=247
Score = 102 bits (253), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 66/159 (41%), Positives = 90/159 (56%), Gaps = 10/159 (6%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
IP VTR A + A LE+I+PF LY N L+ Q+WRLIT FLFFG F
Sbjct 11 QIPAVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILKKYQIWRLITNFLFFGPLGFSF 70
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGV-SSYFFSGSMINVM 132
+N+ L YC LEE R+A F++M + GG+L+ +FG+ S+ FF G +M
Sbjct 71 LFNMIFLYRYCRMLEEGSFRGRTADFVYMFLF-GGVLMT---LFGLFSNLFFLGQAFTIM 126
Query 133 -TYIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
Y+W RRNP R++ F + AP+LP++L SLL G
Sbjct 127 LVYVWSRRNPFVRMNFFGLLNFQAPFLPWVLMGFSLLLG 165
> ath:AT4G21810 DER2.1; DER2.1 (DERLIN-2.1)
Length=244
Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 61/174 (35%), Positives = 93/174 (53%), Gaps = 13/174 (7%)
Query 9 EQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLF 68
+ V+ + +P +TR L A+ V C+LEIISP++LY+N LV Q WRL+T FL+
Sbjct 3 QAVEEWYKQMPIITRSYLTAAVVTTVGCSLEIISPYNLYLNPTLVVKQYQFWRLVTNFLY 62
Query 69 FGTFSLHFFWNVYVLIFYCSTLEEHR---RSATFLWMLICTGGLLLAFSYIFGVSSY--- 122
F L F ++++ L YC LEE+ ++A FL+ML+ +L I G+ Y
Sbjct 63 FRKMDLDFLFHMFFLARYCKLLEENSFRGKTADFLYMLLFGATVLTGIVLIGGMIPYLSV 122
Query 123 ------FFSGSMINVMTYIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
F S S+ +M Y+W ++NP +S A YLP++L S+L G
Sbjct 123 SFSKIIFLSNSLTFMMVYVWSKQNPYIHMSFLGLFTFTAAYLPWVLLGFSILVG 176
> ath:AT4G04860 DER2.2; DER2.2 (DERLIN-2.2); K13989 Derlin-2/3
Length=244
Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 59/174 (33%), Positives = 93/174 (53%), Gaps = 13/174 (7%)
Query 9 EQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLF 68
+ V+ + +P +TR L A+ + C+L+IISP++LY+N LV Q WRL+T FL+
Sbjct 3 QAVEEWYKQMPIITRSYLTAAVITTVGCSLDIISPYNLYLNPTLVVKQYQYWRLVTNFLY 62
Query 69 FGTFSLHFFWNVYVLIFYCSTLEEHR---RSATFLWMLICTGGLLLAFSYIFGVSSY--- 122
F L F ++++ L YC LEE+ ++A FL+ML+ +L I G+ Y
Sbjct 63 FRKMDLDFMFHMFFLARYCKLLEENSFRGKTADFLYMLLFGASVLTGIVLIGGMIPYLSA 122
Query 123 ------FFSGSMINVMTYIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
F S S+ +M Y+W ++NP +S A YLP++L S+L G
Sbjct 123 SFAKIIFLSNSLTFMMVYVWSKQNPYIHMSFLGLFTFTAAYLPWVLLGFSILVG 176
> hsa:91319 DERL3, C22orf14, IZP6, LLN2, MGC71803, derlin-3; Der1-like
domain family, member 3; K13989 Derlin-2/3
Length=235
Score = 88.6 bits (218), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 59/157 (37%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
+P VTR A + A LE++SPF LY N LVF QVWRL+T FLFFG F
Sbjct 12 QVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFFGPLGFSF 71
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINVMT 133
F+N+ + YC LEE R+A F++M + +L S +F +++ ++
Sbjct 72 FFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFG--GVLMTLLGLLGSLFFLGQALMAMLV 129
Query 134 YIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
Y+W RR+P R++ F + AP+LP+ L SLL G
Sbjct 130 YVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLG 166
> mmu:70377 Derl3, 1810006I20Rik, 1810063P04Rik, IZP6, MGC118672,
MGC144274, MGC144275, derlin-3; Der1-like domain family,
member 3; K13989 Derlin-2/3
Length=228
Score = 83.2 bits (204), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 63/157 (40%), Positives = 89/157 (56%), Gaps = 6/157 (3%)
Query 17 HIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHF 76
+P VTR A + A LE++SPF LY N LVF QVWRLIT FLFFG F
Sbjct 12 QVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLITTFLFFGPLGFGF 71
Query 77 FWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINVMT 133
F+N+ + YC LEE R A F++M + GG+L+ G S +F +++ ++
Sbjct 72 FFNMLFVFRYCRMLEEGSFRGRKADFVFMFLF-GGVLMTLLGFLG-SLFFLGQALMAMLV 129
Query 134 YIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGG 169
Y+W RR+P+ R++ F + AP+LP+ L SLL G
Sbjct 130 YVWSRRSPHVRVNFFGLLNFQAPFLPWALMGFSLLLG 166
> cel:R151.6 hypothetical protein; K13989 Derlin-2/3
Length=237
Score = 79.3 bits (194), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 6/161 (3%)
Query 15 LTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSL 74
L +PPVTR A +L LE ++PF LY NW+L+ Q WRLIT F FFG+F
Sbjct 8 LEEMPPVTRFYTGACVLLTTAVHLEFVTPFHLYFNWELIIRKYQFWRLITSFCFFGSFGF 67
Query 75 HFFWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINV 131
F +N+ YC LEE R A F++M + G +L+ S IF V F + +
Sbjct 68 SFLFNMIFTYRYCMMLEEGSFRGRRADFVYMFLF-GAVLMILSGIF-VQILFLGQAFTIM 125
Query 132 MTYIWGRRNPNTRLSIF-FMPVLAPYLPFLLALVSLLGGWN 171
+ YIW RRNP +++ F + APYLP++L L SLL G N
Sbjct 126 LVYIWSRRNPMIQMNFFGVLTFTAPYLPWVLLLFSLLLGNN 166
> ath:AT4G29330 DER1; DER1 (DERLIN-1); K13989 Derlin-2/3
Length=266
Score = 69.3 bits (168), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 83/166 (50%), Gaps = 5/166 (3%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFL 67
M F +PP+T+ L +++P + + +LV Q+WRLIT
Sbjct 1 MSSPGEFYNSLPPITKAYGTLCFFTTVATQLGLVAPVHIALIPELVLKQFQIWRLITNLF 60
Query 68 FFGTFSLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLICTGGLLLAFSYIFGVSSYFF 124
F G FS++F + ++ Y LE+ RR+A FLWM+I LL S I + F
Sbjct 61 FLGGFSINFGIRLLMIARYGVQLEKGPFERRTADFLWMMIFGSFTLLVLSVIPFFWTPFL 120
Query 125 SGSMINVMTYIWGRRNPNTRLSIFFMPVL-APYLPF-LLALVSLLG 168
S++ ++ Y+W R PN +S++ + L A YLP+ +LAL + G
Sbjct 121 GVSLVFMLLYLWSREFPNANISLYGLVTLKAFYLPWAMLALDVIFG 166
> cpv:cgd6_3580 hypothetical protein ; K13989 Derlin-2/3
Length=275
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 38/160 (23%), Positives = 79/160 (49%), Gaps = 6/160 (3%)
Query 16 THIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLH 75
++PP+TR L + L T +++P+ + +W+ +F AQ+WR +T F F G FS+
Sbjct 12 KNLPPITRSILTITFFSTLLITFGMLNPWYILFDWEYIFRKAQIWRFLTSFFFVGPFSIG 71
Query 76 FFWNVYVLIFYCSTLEEHRRSAT------FLWMLICTGGLLLAFSYIFGVSSYFFSGSMI 129
+ + ++ + S LE + + +++ TG ++ ++ + S+I
Sbjct 72 WIMSQWMFTSFSSKLERSGSVGSSSGSYLYFILILMTGINIIGTAFDYPTGRKIGGSSLI 131
Query 130 NVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGG 169
+ Y W ++ P + +SI+ + A LP+ L + +L G
Sbjct 132 FGIIYYWSKKFPTSLVSIWGFTLQAYQLPYALLFLDVLTG 171
> tpv:TP04_0764 hypothetical protein
Length=240
Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 10/160 (6%)
Query 18 IPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHFF 77
+P TR + + L +++ P L +NW+LV Q+WRL+T L+ G FSL
Sbjct 14 LPRFTRTFITIILGITLLSFFKVLDPSKLLLNWELVLQKFQIWRLVTSVLYVGPFSLR-- 71
Query 78 WNVYVLIF--YCSTLEE-----HRRSATFLWMLICTGGLLLAFSYIFGVSSY-FFSGSMI 129
W ++L+F + S+LE H A ++ I + L + F S Y + + S++
Sbjct 72 WIFFILLFSQFSSSLENNSVFTHSPGAYLYFLFIQSIFLACISAGFFWPSGYPYLADSLL 131
Query 130 NVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGG 169
+ Y W +R+ T +SI+F V A LPF L + L+ G
Sbjct 132 FAIIYYWSKRDMWTIVSIYFFNVKAYQLPFALLFLHLVMG 171
> tgo:TGME49_094290 der1-like family domain-containing protein,
conserved ; K13989 Derlin-2/3
Length=293
Score = 56.2 bits (134), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 7/166 (4%)
Query 2 SAHGLKMEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWR 61
S G + + +PPVTR + L ++E++ L ++W+LVF QVWR
Sbjct 10 SGGGYPSNGPEAWFFSLPPVTRAVTCITFACTLLSSIELMPARLLILDWELVFQKLQVWR 69
Query 62 LITCFLFFGTFSLHFFWNVYVLIFYCSTLEEH-----RRSATFLWMLICTGGLLLAFSYI 116
L+T L+ G FSL + ++Y+ S LE + +L+ ++ L S +
Sbjct 70 LLTNVLYIGRFSLGWVLHMYMWTQVSSDLENNAVFVQASKGAYLYFIVLQTLCLDCISLL 129
Query 117 --FGVSSYFFSGSMINVMTYIWGRRNPNTRLSIFFMPVLAPYLPFL 160
+ + GS++ + Y W RR T +SI+F+ V LPF+
Sbjct 130 LFWPTGLHLLGGSLLFAVLYYWSRRESYTPVSIYFLTVQGHQLPFV 175
> cel:F25D7.1 cup-2; Coelomocyte UPtake defective family member
(cup-2); K11519 Derlin-1
Length=245
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/164 (31%), Positives = 79/164 (48%), Gaps = 19/164 (11%)
Query 10 QVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFF 69
++ FL IP VTR +AST++ L I+ +++ W LV Q WR +T +++
Sbjct 2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYY 61
Query 70 ---GTFSLHFFWNVYVLIFYCSTLEEHR---RSATFLWMLI-----CTGGLLLAFSYIFG 118
H+ Y L Y LE RSA +L+MLI C+ GL +A
Sbjct 62 PVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCS-GLCMA------ 114
Query 119 VSSYFFSGSMINVMTYIWGRRNPNTRLSIFF-MPVLAPYLPFLL 161
+ YF M+ + Y+W + N +T +S +F M A YLP++L
Sbjct 115 LDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVL 158
> pfa:PF10_0317 DER1-like protein, putative; K13989 Derlin-2/3
Length=263
Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 38/169 (22%), Positives = 84/169 (49%), Gaps = 5/169 (2%)
Query 6 LKMEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITC 65
+ + +++ ++P VT+ + ++ L T +++ + ++W L++ +WR+
Sbjct 1 MDISGPEVWYNNLPNVTKYVITLIFLVTLLITCNLLNVVYILLDWNLIYYKYHIWRIFLN 60
Query 66 FLFFGTFSLHFFWNVYVLIFYCSTLEEH---RRSATFLWMLI--CTGGLLLAFSYIFGVS 120
FL+ G FSL + + + + + S+LE++ ++L+ + CT L++ + +
Sbjct 61 FLYVGKFSLSWVFFMSLFAQFSSSLEKNGIFTSPGSYLYFITIQCTFLSLISILFYWPRG 120
Query 121 SYFFSGSMINVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGG 169
F S++ + Y W RR + +SI+F V LPF L + L+ G
Sbjct 121 YPFLGNSLLFAIIYYWSRREAWSHVSIYFFTVKGYQLPFALIFLHLIMG 169
> sce:YDR411C DFM1; Dfm1p; K13989 Derlin-2/3
Length=341
Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 24/186 (12%)
Query 4 HGLKMEQVDL-----FLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQ 58
HG D+ F +IPP+TR + V+ + L +I+P+ W L F Q
Sbjct 11 HGNGGRNNDVMGPKEFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFIYVWNLTFKKVQ 70
Query 59 VWRLITCFLFFGTFSLHFFWNVYVLIFYCSTLEE--------HRRSATFL-----WMLIC 105
+WRL+T + + ++ +Y + S LE +RR ++ C
Sbjct 71 IWRLLTSCVMLSSRAMPALMELYSIYDRSSQLERGHFGPGLSNRRGPMVTVDYAYYLCFC 130
Query 106 TGGLLLAFSYIFGVSSYF---FSGSMINVMTYIWGRRNPNTRLSIF-FMPVLAPYLPFLL 161
+ A + I+G SY+ + I+ +TY W N N ++ + +PV Y P +
Sbjct 131 ILAITTATTIIYG--SYYPVVLTSGFISCITYTWSIDNANVQIMFYGLIPVWGKYFPLIQ 188
Query 162 ALVSLL 167
+S +
Sbjct 189 LFISFV 194
> bbo:BBOV_III010270 17.m07890; hypothetical protein
Length=83
Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 22/42 (52%), Positives = 31/42 (73%), Gaps = 0/42 (0%)
Query 128 MINVMTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGG 169
MIN++TYIWGR+NP R+ I F+ V APYLP+++ +S G
Sbjct 1 MINILTYIWGRKNPYNRVGIIFLNVPAPYLPWVMLALSHFSG 42
> bbo:BBOV_III008600 17.m10680; Der1-like family protein; K13989
Derlin-2/3
Length=262
Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 39/161 (24%), Positives = 78/161 (48%), Gaps = 6/161 (3%)
Query 18 IPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHFF 77
+P VT+ + + +L T +IIS S+ ++WQ++ V R++ L+ G FS +
Sbjct 17 LPKVTKTIITSMFILTLFTTFKIISLQSIVLDWQIIRKTYGVHRILLACLYAGQFSFRWV 76
Query 78 WNVYVLIFYCSTLEEH----RRSATFLWMLICTGGLLLAFSYIFGVSSY--FFSGSMINV 131
Y+ + +TLE + ++L+ ++ L+ S IF S F + +++
Sbjct 77 IQAYMFSQFSTTLERNPVFSSSVGSYLYFILIEVVLICLISLIFYWPSGFPFLNDALMFS 136
Query 132 MTYIWGRRNPNTRLSIFFMPVLAPYLPFLLALVSLLGGWNM 172
+ Y W +R+ +SI+ V A LP+ + ++ + G M
Sbjct 137 ILYYWSKRDMWNSVSIYVFTVKAYQLPYAMLFLNFIMGAPM 177
> sce:YBR201W DER1; Der1p; K13989 Derlin-2/3
Length=211
Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query 15 LTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSL 74
L IP VTR+ + VL L +L I+ P + ++ LVF Q RL+ +G F+
Sbjct 9 LGDIPLVTRLWTIGCLVLSGLTSLRIVDPGKVVYSYDLVFKKGQYGRLLYSIFDYGAFNW 68
Query 75 HFFWNVYVLIFYCSTLEEH---RRSATFLWML 103
N++V + STLE RR F W++
Sbjct 69 ISMINIFVSANHLSTLENSFNLRRK--FCWII 98
> dre:406753 derl1, wu:fb09d07, wu:fb94d05, wu:fj92g12, zgc:55637;
Der1-like domain family, member 1; K11519 Derlin-1
Length=256
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 26/178 (14%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHA-QVWRLITCF 66
M + + +IP +TR S + + L +I P L + W F H Q+WR IT
Sbjct 1 MSDIGDWFKNIPFITRYWFAGSIAVPLIGKLGLIGPMYLVL-WPEAFFHKFQIWRPITAT 59
Query 67 LFF----GTFSLHFFWNVYVLIFYCSTLEE---HRRSATFL------WMLICTGGLLLAF 113
L+F GT L+ N+Y L Y S LE R A ++ W+ I GL++
Sbjct 60 LYFPVGPGTGFLYLV-NLYFLYQYSSRLETGAFDGRPADYMFMLLFNWICIVITGLIMDM 118
Query 114 SYIFGVSSYFFSGSMINVMTYIWGRRNPNTRLSIFFMPVL-APYLPF-LLALVSLLGG 169
+ +I + Y+W + N +T +S +F A YLP+ +L ++GG
Sbjct 119 QLLM--------IPLIMSVLYVWAQLNRDTIVSFWFGTRFKACYLPWVILGFNYIIGG 168
> hsa:79139 DERL1, DER-1, DER1, FLJ13784, FLJ42092, MGC3067, PRO2577;
Der1-like domain family, member 1; K11519 Derlin-1
Length=231
Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHA-QVWRLITCF 66
M + + IP +TR A+ + + L +ISP L++ W F + Q+WR IT
Sbjct 1 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFL-WPEAFLYRFQIWRPITAT 59
Query 67 LFF----GTFSLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLI 104
+F GT L+ N+Y L Y + LE R A +L+ML+
Sbjct 60 FYFPVGPGTGFLYLV-NLYFLYQYSTRLETGAFDGRPADYLFMLL 103
> mmu:67819 Derl1, 1110021N07Rik, AI195141, AW551338, Derlin-1;
Der1-like domain family, member 1; K11519 Derlin-1
Length=251
Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 10/105 (9%)
Query 8 MEQVDLFLTHIPPVTRVCLVASTVLMALCTLEIISPFSLYMNWQLVFAHA-QVWRLITCF 66
M + + IP +TR A+ + + L IISP ++ W F + Q+WR T
Sbjct 1 MSDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFL-WPEAFLYRFQIWRPFTAT 59
Query 67 LFF----GTFSLHFFWNVYVLIFYCSTLEE---HRRSATFLWMLI 104
+F GT L+ N+Y L Y + LE R A +L+ML+
Sbjct 60 FYFPVGPGTGFLYLV-NLYFLYQYSTRLEAGAFDGRPADYLFMLL 103
> bbo:BBOV_IV000300 21.m03031; Der1-like family
Length=276
Score = 36.2 bits (82), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 28/172 (16%)
Query 15 LTHIPPVTRVCLVASTVLMALC-------TLEIISPFSLYMNWQLVFAHAQVWRLITCFL 67
+ +PPVT + ST++ L LEI+ F L F ++WR++T FL
Sbjct 61 IKRLPPVTSSYITLSTIMALLSWGFNDNYPLEILQ-FDLK-----SFKSGKIWRILTPFL 114
Query 68 FFGTFSL-HFF-------WNVYVLIFYCSTLEEHRRSATFLWMLICTGGLLLAFSYIFGV 119
FG L H F + V + +C+ E+ TF M I GL + +FG
Sbjct 115 NFGQLWLAHIFMAQSVALYMASVEVSHCAKPEKFLEFMTFGTMCISLYGLADS---LFGK 171
Query 120 SSYFFSGSMINVMTYI---WGRRNPNTRLSIFFMPVL-APYLPFLLALVSLL 167
+ ++ TY+ W R N T ++ F + L A +PF+ L + L
Sbjct 172 QENTMGSAAYHLHTYVLYYWSRLNEGTVVNCFDLFNLPAEMVPFIFVLQNYL 223
> eco:b2167 fruA, ECK2160, JW2154, ptsF; fused fructose-specific
PTS enzymes: IIBcomponent/IIC components; K02769 PTS system,
fructose-specific IIB component [EC:2.7.1.69]; K02770 PTS
system, fructose-specific IIC component
Length=563
Score = 32.7 bits (73), Expect = 0.66, Method: Composition-based stats.
Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query 98 TFLWMLICTGGLLLAFSYIFGVSSYFFSGSMINVMTYIWGRRNPNTRLSIFFMPVLAPYL 157
+++ ++ GGL +A S+ FG+ ++ G++ + I G +PVLA Y+
Sbjct 235 SYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGG-----GSAFALMVPVLAGYI 289
Query 158 PFLLA 162
F +A
Sbjct 290 AFSIA 294
> pfa:PF14_0498 DER1; Degradation in the ER (DER1) like protein,
putative
Length=354
Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Query 41 ISPFSLYMNWQLVFAHAQVWRLITCFLFFGTFSLHFFWNVYVLIFYCSTLEEHRRSATFL 100
+ P + ++ + V + +R+ T LF+G SL+ N+Y+L + LE S+ L
Sbjct 172 LKPEDIALHSKRVLRAFEFYRIYTSALFYGDISLYVLTNIYMLYVQSNQLENILGSSEML 231
Query 101 WMLICTGGLLLAFSYIFGVSSYFFSGSMINVMTYIWGRRNPNTRLS-IFFMPVLAPYLPF 159
I +L F+S +++ + ++ NP + + IF + + YLP+
Sbjct 232 SYYISQISILSIICSYIKKP--FYSTALLKSLLFVNCMLNPYQKANLIFGININNMYLPY 289
Query 160 LLALVSLLGGWNM 172
L L+ ++ N+
Sbjct 290 LSILIDIIHAQNL 302
> pfa:MAL8P1.151 inositol phosphatase, putative
Length=1419
Score = 30.0 bits (66), Expect = 4.4, Method: Composition-based stats.
Identities = 9/29 (31%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Query 58 QVWRLITCFLFFGTFSLHFFWNVYVLIFY 86
++WRLI+C+ + ++F N++ L++Y
Sbjct 836 RIWRLISCYNYLNYLKIYF--NIFFLLYY 862
Lambda K H
0.335 0.144 0.489
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4341553636
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40