bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_3759_orf1
Length=248
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_094360 ubiquitin carboxyl-terminal hydrolase, putat... 297 2e-80
bbo:BBOV_II005180 18.m06428; u4/u6.u5 tri-snRNP-associated 65 ... 232 1e-60
ath:AT4G22350 ubiquitin carboxyl-terminal hydrolase family pro... 197 4e-50
ath:AT4G22285 ubiquitin thiolesterase/ zinc ion binding 195 1e-49
ath:AT4G22410 ubiquitin carboxyl-terminal hydrolase family pro... 193 4e-49
dre:790924 usp39, wu:fb54d10, wu:fb79f05, zgc:158428; ubiquiti... 164 3e-40
pfa:PF13_0096 Ubiquitin Carboxyl-terminal Hydrolase-like zinc ... 160 4e-39
mmu:28035 Usp39, AA408960, AI894154, CGI-21, D6Wsu157e, SAD1; ... 158 2e-38
hsa:10713 USP39, HSPC332, MGC75069, SAD1, SNRNP65; ubiquitin s... 157 3e-38
tpv:TP02_0821 ubiquitin carboxyl-terminal hydrolase; K12847 U4... 155 9e-38
cel:F09D1.1 hypothetical protein; K12847 U4/U6.U5 tri-snRNP-as... 139 8e-33
sce:YFR005C SAD1; Conserved zinc-finger domain protein involve... 64.7 3e-10
cpv:cgd5_2350 SnRNP assembly defective 1 like ubiquitin C-term... 57.4 5e-08
tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putat... 48.1 3e-05
mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap1... 46.6 9e-05
hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH... 46.2 1e-04
cel:H34C03.2 hypothetical protein; K11835 ubiquitin carboxyl-t... 45.1 2e-04
dre:100329394 usp46, si:ch73-16a12.1; ubiquitin specific pepti... 45.1 3e-04
hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin spec... 43.9 5e-04
mmu:216835 Usp43, 9130017K11Rik, B930051C24, C630032K07Rik; ub... 43.9 6e-04
hsa:124739 USP43, FLJ30626; ubiquitin specific peptidase 43 (E... 43.5 7e-04
mmu:75083 Usp50, 1700086G18Rik, 4930511O11Rik; ubiquitin speci... 43.1 8e-04
hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3... 43.1 0.001
mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiqu... 42.4 0.002
hsa:64854 USP46, FLJ11850, FLJ12552, FLJ14283, FLJ39393; ubiqu... 41.6 0.003
dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin spec... 41.6 0.003
xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (pr... 41.2 0.003
mmu:69727 Usp46, 1190009E20Rik, 2410018I08Rik, AI451644; ubiqu... 41.2 0.003
pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative... 41.2 0.003
mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin sp... 40.8 0.004
tpv:TP03_0714 hypothetical protein 40.0 0.007
dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiq... 40.0 0.008
dre:561425 novel protein similar to vertebrate ubiquitin speci... 40.0 0.008
dre:569700 usp16, si:ch211-238e22.5, si:dkey-121n8.2, wu:fc76b... 39.3 0.015
dre:569679 usp3, fe50h06, wu:fe50h06; ubiquitin specific pepti... 38.9 0.017
dre:568334 ubiquitin specific protease 11-like 38.9 0.017
hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.... 38.5 0.020
dre:100149276 ubiquitin specific protease 43-like; K11856 ubiq... 38.5 0.020
ath:AT4G10570 UBP9; UBP9 (UBIQUITIN-SPECIFIC PROTEASE 9); cyst... 38.5 0.021
mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;... 38.1 0.028
ath:AT4G39910 ATUBP3; ATUBP3 (ARABIDOPSIS THALIANA UBIQUITIN-S... 37.7 0.034
ath:AT1G32850 UBP11; UBP11 (UBIQUITIN-SPECIFIC PROTEASE 11); c... 37.7 0.041
mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific pepti... 37.4 0.046
cel:ZK328.1 cyk-3; CYtoKinesis defect family member (cyk-3); K... 37.0 0.059
dre:563983 novel protein similar to vertebrate ubiquitin speci... 36.6 0.082
hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC... 36.6 0.085
ath:AT4G10590 UBP10; ubiquitin carboxyl-terminal hydrolase fam... 36.2 0.11
hsa:57602 USP36, DUB1; ubiquitin specific peptidase 36 (EC:3.4... 36.2 0.13
mmu:84092 Usp8, AI574262, AW557536, Ubpy, mKIAA0055; ubiquitin... 35.4 0.18
mmu:72344 Usp36, 2700002L06Rik, mKIAA1453; ubiquitin specific ... 35.4 0.19
> tgo:TGME49_094360 ubiquitin carboxyl-terminal hydrolase, putative
(EC:4.1.1.70 3.1.2.15); K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=571
Score = 297 bits (761), Expect = 2e-80, Method: Compositional matrix adjust.
Identities = 150/227 (66%), Positives = 176/227 (77%), Gaps = 8/227 (3%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
D YNL+PTYT EDVA+LS + YGK+LDGAD++PGCVGLNNL +TDF +IQSLCT+
Sbjct 157 DDIIYNLHPTYTKEDVAQLSTRIIYGKALDGADYIPGCVGLNNLKRTDFCNAMIQSLCTV 216
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
+PLRN+LLLLDLS Q Y+ VL+TL ELMRKIFN RNFKGIVSPHEFLQAVGV SKKKFR
Sbjct 217 VPLRNWLLLLDLSHVQNYDPVLQTLGELMRKIFNARNFKGIVSPHEFLQAVGVASKKKFR 276
Query 147 IGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEVLV--TDAQSEEG------RK 198
IGEQ+DPL F WL+ +H+ K KK ++++DCFQGEV V T A+ E +
Sbjct 277 IGEQADPLQFFCWLMTRVHQSAKHKKLNSNVVNDCFQGEVEVRTTTAEGEATGQPPSVSR 336
Query 199 TPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGETDSGPTP 245
PFL+LTLDLP APIFKDSLDRNMIP +PIFDLLQKF+GE TP
Sbjct 337 VPFLFLTLDLPQAPIFKDSLDRNMIPHIPIFDLLQKFNGEQIQEATP 383
> bbo:BBOV_II005180 18.m06428; u4/u6.u5 tri-snRNP-associated 65
kDa protein; K12847 U4/U6.U5 tri-snRNP-associated protein
2
Length=470
Score = 232 bits (591), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 115/209 (55%), Positives = 147/209 (70%), Gaps = 2/209 (0%)
Query 33 LNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNY 92
L P YT E V + ++ YGK LDG DF+PGC+GLNNL +TD+F VIIQ LCT+ +RNY
Sbjct 128 LKPKYTKEYVENIDTKIVYGKGLDGTDFIPGCIGLNNLKQTDYFNVIIQVLCTVATVRNY 187
Query 93 LLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSD 152
LLLLD+ Q ++V+ TL EL+RKI+N +NFKGIVSPHEFLQAVGV SK ++IG +D
Sbjct 188 LLLLDIDRIQPPDNVISTLVELIRKIYNTKNFKGIVSPHEFLQAVGVASKGLYKIGVHND 247
Query 153 PLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGE--VLVTDAQSEEGRKTPFLYLTLDLPP 210
P+AL WLLN L ++KKT SI+ F G+ V D + + TPF +TLD+P
Sbjct 248 PVALLTWLLNRLDTKLRNKKTKESIVAKAFGGQLNVYTQDGDNWTQKITPFKMITLDVPN 307
Query 211 APIFKDSLDRNMIPTVPIFDLLQKFDGET 239
APIFKD ++N+IP V IF LLQKF GE+
Sbjct 308 APIFKDDKEKNIIPQVSIFQLLQKFQGES 336
> ath:AT4G22350 ubiquitin carboxyl-terminal hydrolase family protein;
K12847 U4/U6.U5 tri-snRNP-associated protein 2
Length=510
Score = 197 bits (500), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 110/217 (50%), Positives = 147/217 (67%), Gaps = 5/217 (2%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
D ++ LNP ++ V L + ++LDG+D+LPG VGLNN+ KT+F V IQSL +
Sbjct 162 DDIRHVLNPRFSRAQVNELDKNRQWSRALDGSDYLPGMVGLNNIQKTEFVNVTIQSLMRV 221
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
PLRN+ L+ + + K + + EL RKI++ RNFKG VSPHEFLQAV SKK+FR
Sbjct 222 TPLRNFFLIPENYQHCK-SPLGHRFGELTRKIWHARNFKGQVSPHEFLQAVMKASKKRFR 280
Query 147 IGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEV-LVTDAQSEEGR---KTPFL 202
IG+QSDP+ +WLLN LH D + K SIIH CFQGE+ +V + Q E + + PFL
Sbjct 281 IGQQSDPVEFMSWLLNTLHMDLRTSKDASSIIHKCFQGELEVVKEYQGNENKEISRMPFL 340
Query 203 YLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGET 239
L LDLPP P+FKD +++N+IP V +FDLL+KFDGET
Sbjct 341 MLGLDLPPPPLFKDVMEKNIIPQVALFDLLKKFDGET 377
> ath:AT4G22285 ubiquitin thiolesterase/ zinc ion binding
Length=541
Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 109/217 (50%), Positives = 147/217 (67%), Gaps = 5/217 (2%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
D ++ LNP ++ V L + ++LDG+D+LPG VGLNN+ KT+F V IQSL +
Sbjct 193 DDIRHVLNPRFSRAQVNELDKNRQWSRALDGSDYLPGMVGLNNIQKTEFVNVTIQSLMRV 252
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
PLRN+ L+ + + K + ++ EL RKI++ RNFKG VSPHEFLQAV SKK+FR
Sbjct 253 TPLRNFFLIPENYQHCK-SPLVHRFGELTRKIWHARNFKGQVSPHEFLQAVMKASKKRFR 311
Query 147 IGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEV-LVTDAQSEEGR---KTPFL 202
IG+QSDP+ +WLLN LH D + K SIIH CFQGE+ +V + Q E + + FL
Sbjct 312 IGQQSDPVEFMSWLLNTLHMDLRTSKDASSIIHKCFQGELEVVKEFQGNENKEISRMSFL 371
Query 203 YLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGET 239
L LDLPP P+FKD +++N+IP V +FDLL+KFDGET
Sbjct 372 MLGLDLPPPPLFKDVMEKNIIPQVALFDLLKKFDGET 408
> ath:AT4G22410 ubiquitin carboxyl-terminal hydrolase family protein
Length=340
Score = 193 bits (491), Expect = 4e-49, Method: Compositional matrix adjust.
Identities = 108/217 (49%), Positives = 146/217 (67%), Gaps = 5/217 (2%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
D ++ LNP ++ V L + ++LDG+D+LPG VGLNN+ KT+F V IQSL +
Sbjct 78 DDIRHVLNPRFSRAQVNELDKNRQWSRALDGSDYLPGMVGLNNIQKTEFVNVTIQSLMRV 137
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
PLRN+ + + + K + ++ EL RKI++ RNFKG VSPHEFLQAV SKK+FR
Sbjct 138 TPLRNFFHIPENYQHCK-SPLVHCFGELTRKIWHARNFKGQVSPHEFLQAVMKASKKRFR 196
Query 147 IGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEV-LVTDAQSEEGR---KTPFL 202
IG+QSDP+ +WLLN LH D + K SIIH CFQGE+ +V + Q E + + FL
Sbjct 197 IGQQSDPVEFMSWLLNTLHMDLRTSKDASSIIHKCFQGELEVVKEFQGNENKEISRMSFL 256
Query 203 YLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGET 239
L LDLPP P+FKD +++N+IP V +FDLL+KFDGET
Sbjct 257 MLGLDLPPPPLFKDVMEKNIIPQVALFDLLKKFDGET 293
> dre:790924 usp39, wu:fb54d10, wu:fb79f05, zgc:158428; ubiquitin
specific peptidase 39; K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=497
Score = 164 bits (415), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 92/241 (38%), Positives = 133/241 (55%), Gaps = 36/241 (14%)
Query 31 YNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLR 90
Y L PT+T + ++ L + ++ DG +LPG VGLNN+ D+ V++Q+L + PLR
Sbjct 122 YVLKPTFTKQHISGLDKQGKLYRAYDGTTYLPGIVGLNNIKANDYANVVLQALSNVPPLR 181
Query 91 NYLLLLDLSEKQKYNSV-----------LKTLSELMRKIFNRRNFKGIVSPHEFLQAVGV 139
NY L E++ Y + ++ ELMRK++N RNFK VSPHE LQAV +
Sbjct 182 NYFL-----EEENYRGIRRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVL 236
Query 140 ESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEV------------- 186
SKK F+I +Q D + +W LN LH K SII FQG +
Sbjct 237 CSKKTFQITKQGDAVDFLSWFLNALHGALGGTKKKSSIITKAFQGSMRIFSKKLPHPDLP 296
Query 187 -------LVTDAQSEEGRKTPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGET 239
L+ + EE ++ FLYLTLDLP AP++KD ++ +IP VP+F++L KF+G T
Sbjct 297 PEEKEALLLKEEYQEEMSESTFLYLTLDLPTAPLYKDEKEQLIIPQVPLFNILGKFNGNT 356
Query 240 D 240
+
Sbjct 357 E 357
> pfa:PF13_0096 Ubiquitin Carboxyl-terminal Hydrolase-like zinc
finger protein; K12847 U4/U6.U5 tri-snRNP-associated protein
2
Length=640
Score = 160 bits (405), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 80/140 (57%), Positives = 97/140 (69%), Gaps = 1/140 (0%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
+ KY L PTY E V L GKSLDG DFLPG VGLNNL TD+ VIIQ +C+I
Sbjct 170 NDIKYFLKPTYNKEQVEHLCYNSVLGKSLDGGDFLPGLVGLNNLKNTDYCNVIIQLICSI 229
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
IPLRN LLL + E N ++ LS+L++KI+N RNFKG+VSPHEFLQAVG+ES K F+
Sbjct 230 IPLRNTLLLYECKENIAKN-IIVVLSDLIKKIYNPRNFKGVVSPHEFLQAVGIESNKNFK 288
Query 147 IGEQSDPLALFAWLLNVLHR 166
IG + PL F WLLN ++R
Sbjct 289 IGTKKYPLDFFLWLLNKIYR 308
Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 27/55 (49%), Positives = 38/55 (69%), Gaps = 0/55 (0%)
Query 187 LVTDAQSEEGRKTPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGETDS 241
LV +++ K PF L+L LP AP+FK + + N+IP V IF+LL KFDGET++
Sbjct 452 LVKKNKNDLIVKIPFRTLSLKLPNAPVFKSTTESNIIPQVSIFELLSKFDGETET 506
> mmu:28035 Usp39, AA408960, AI894154, CGI-21, D6Wsu157e, SAD1;
ubiquitin specific peptidase 39; K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=564
Score = 158 bits (399), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 91/242 (37%), Positives = 134/242 (55%), Gaps = 37/242 (15%)
Query 31 YNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLR 90
Y L PT+T + +A L + ++ DG +LPG VGLNN+ D+ ++Q+L + PLR
Sbjct 190 YVLKPTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLR 249
Query 91 NYLLLLDLSEKQKYNSV-----------LKTLSELMRKIFNRRNFKGIVSPHEFLQAVGV 139
NY L E+ Y ++ ++ ELMRK++N RNFK VSPHE LQAV +
Sbjct 250 NYFL-----EEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVL 304
Query 140 ESKKKFRIGEQSDPLALFAWLLNVLHRD-QKDKKTGGSIIHDCFQG-------------- 184
SKK F+I +Q D + +W LN LH KK +I++D FQG
Sbjct 305 CSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVNDVFQGSMRIFTKKLPHPDL 364
Query 185 ------EVLVTDAQSEEGRKTPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGE 238
++L D E ++ F+YLTLDLP AP++KD ++ +IP VP+F++L KF+G
Sbjct 365 PAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGI 424
Query 239 TD 240
T+
Sbjct 425 TE 426
> hsa:10713 USP39, HSPC332, MGC75069, SAD1, SNRNP65; ubiquitin
specific peptidase 39; K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=565
Score = 157 bits (397), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 91/242 (37%), Positives = 133/242 (54%), Gaps = 37/242 (15%)
Query 31 YNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLR 90
Y L PT+T + +A L + ++ DG +LPG VGLNN+ D+ ++Q+L + PLR
Sbjct 191 YVLKPTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLR 250
Query 91 NYLLLLDLSEKQKYNSV-----------LKTLSELMRKIFNRRNFKGIVSPHEFLQAVGV 139
NY L E+ Y ++ ++ ELMRK++N RNFK VSPHE LQAV +
Sbjct 251 NYFL-----EEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVL 305
Query 140 ESKKKFRIGEQSDPLALFAWLLNVLHRD-QKDKKTGGSIIHDCFQG-------------- 184
SKK F+I +Q D + +W LN LH KK +I+ D FQG
Sbjct 306 CSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVTDVFQGSMRIFTKKLPHPDL 365
Query 185 ------EVLVTDAQSEEGRKTPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGE 238
++L D E ++ F+YLTLDLP AP++KD ++ +IP VP+F++L KF+G
Sbjct 366 PAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGI 425
Query 239 TD 240
T+
Sbjct 426 TE 427
> tpv:TP02_0821 ubiquitin carboxyl-terminal hydrolase; K12847
U4/U6.U5 tri-snRNP-associated protein 2
Length=537
Score = 155 bits (393), Expect = 9e-38, Method: Compositional matrix adjust.
Identities = 78/174 (44%), Positives = 115/174 (66%), Gaps = 12/174 (6%)
Query 80 IQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGV 139
I+ +C ++PLRN L+ D+++ Q + V+ TLS+L+RKIFN +NFKGIVSPHEF+Q+VG+
Sbjct 228 IKLICVVVPLRNLFLVFDVNKVQPPDPVITTLSQLIRKIFNVKNFKGIVSPHEFVQSVGI 287
Query 140 ESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKTGG----------SIIHDCFQGEVLVT 189
+ ++IG QSDP++L +WLL +H+ +K T G SI+ F GE+L+
Sbjct 288 VTNGLYKIGVQSDPVSLLSWLLARIHQKLHNKNTKGSFKTSFHIVESIVTKTFGGELLIK 347
Query 190 DAQSE--EGRKTPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKFDGETDS 241
+ E + PF L+L +P APIFKDS+D N IP IF+LL K+DG T++
Sbjct 348 TLKKNRWETERQPFRMLSLTVPEAPIFKDSMDTNAIPQAQIFELLSKYDGVTET 401
> cel:F09D1.1 hypothetical protein; K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=602
Score = 139 bits (351), Expect = 8e-33, Method: Compositional matrix adjust.
Identities = 87/245 (35%), Positives = 126/245 (51%), Gaps = 36/245 (14%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
+ KY L PTYT E +A + + ++ D + + PG VGLNN+ D+ I+Q+L +
Sbjct 218 EDIKYVLKPTYTKEMIASIDKQSKMVRAYDDSTYFPGVVGLNNIKANDYCNAILQALSAV 277
Query 87 IPLRNYLLLLDLSEKQKYNSVLK-----------TLSELMRKIFNRRNFKGIVSPHEFLQ 135
PLRN+ L ++ Y S+ + EL+RK++N R + VSPHE LQ
Sbjct 278 RPLRNWFL-----KESNYTSIKRPPGDKLTLLPQRFGELIRKLWNPRALRTHVSPHEMLQ 332
Query 136 AVGVESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGE--------VL 187
AV V S KKF+ +Q+D +LL LH SII F+G +
Sbjct 333 AVVVCSNKKFQFIKQNDAADFMLFLLTTLHSALNGTDKKPSIISKTFRGRMRQYSRRVIP 392
Query 188 VTDAQSEEGRK------------TPFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKF 235
D E+ K +PFLYLTLDLP AP+++D +N+IP VP+ LL+KF
Sbjct 393 AEDTDEEKYMKLRMPEYQEKVIESPFLYLTLDLPSAPLYRDVQLQNIIPQVPLSTLLEKF 452
Query 236 DGETD 240
DG+T+
Sbjct 453 DGKTE 457
> sce:YFR005C SAD1; Conserved zinc-finger domain protein involved
in pre-mRNA splicing, required for assembly of U4 snRNA
into the U4/U6 particle; K12847 U4/U6.U5 tri-snRNP-associated
protein 2
Length=448
Score = 64.7 bits (156), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 101/218 (46%), Gaps = 21/218 (9%)
Query 27 DTFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTI 86
++ K+ PTY P+D+ + F L +L G +G N + D+ ++ + +
Sbjct 115 NSIKFAAYPTYCPKDLEDFPRQCF---DLSNRTYLNGFIGFTNAATYDYAHSVLLLISHM 171
Query 87 IPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFR 146
+P+R++ LL + ++ +K LS ++KI++ + FK +S +F+ + V
Sbjct 172 VPVRDHFLLNHFDNQGEF---IKRLSICVKKIWSPKLFKHHLSVDDFVSYLKVREGLNLN 228
Query 147 IGEQSDPLALFAWLLNVLHRDQKDKKTGGSIIHDCFQGEVLVTDAQSE-EGRKT------ 199
DP WL N + D K SI++ +G+V + +++ E ++
Sbjct 229 ---PIDPRLFLLWLFNKICSSSNDLK---SILNHSCKGKVKIAKVENKPEASESVTGKVI 282
Query 200 --PFLYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKF 235
PF LTLDLP F+D + +P + I LL KF
Sbjct 283 VKPFWVLTLDLPEFSPFEDGNSVDDLPQINITKLLTKF 320
> cpv:cgd5_2350 SnRNP assembly defective 1 like ubiquitin C-terminal
hydrolase with a UBP finger at the N-terminus ; K12847
U4/U6.U5 tri-snRNP-associated protein 2
Length=498
Score = 57.4 bits (137), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 45/210 (21%)
Query 33 LNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNY 92
L P + E ++ +V ++ DG +F PG +GL+N D II L I R+
Sbjct 100 LQPRFNSEIISSSLYDV--SRTFDGIEFSPGFIGLSNFGNNDSLNSIILILSRITEFRDL 157
Query 93 LLLLDLS----EKQKYNSVLKTLSELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKF--- 145
L L EK+ + +L ++ E ++KI+N N KG SP+ ++ + +S KF
Sbjct 158 CLSYQLYSKEIEKRIPDPLLFSIIESIQKIYNPNNLKGKFSPYNLVKIIEKKSNGKFSFS 217
Query 146 ---------------RIGEQS----DPLALFAWLLNVLHR-----------------DQK 169
+G Q+ DP+ALF+W+ L + D+
Sbjct 218 KISNISTSSNSFIQSNVGTQNSTIIDPMALFSWITYNLKKKIDKYLRKFQIKFIPDIDKN 277
Query 170 DKKTGGSIIHDCFQGEVLVTDAQSEEGRKT 199
K+ +I C +GE+ ++ +K+
Sbjct 278 TNKSNMNIFDVCIKGELYNKASKYPNNKKS 307
> tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1100
Score = 48.1 bits (113), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 42/188 (22%)
Query 63 GCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNR- 121
G GL+NL T F +Q L ++PL Y L +V+ T L R
Sbjct 353 GICGLSNLGNTCFLNSAVQCLSKVLPLSYYFLSGKFVADINEENVMGTQGRLARAYHATL 412
Query 122 RNF----KGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD---------- 167
R+ + ++P + AVG +++F Q D L A+LL+ LH D
Sbjct 413 RDMWFGGESSLAPRDLKAAVG-RVREEFLGYNQQDSQELIAFLLDGLHEDLNRIKKKPYY 471
Query 168 --------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT-----PFL 202
Q+ K+ S+I D FQG+ + + RK PF+
Sbjct 472 ESKIEGGPEKPDAQVAELSWQRHKEINDSVIVDLFQGQYR-SRLECPACRKVSVTFDPFM 530
Query 203 YLTLDLPP 210
YL+L +PP
Sbjct 531 YLSLPVPP 538
> mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap18,
mKIAA0529; ubiquitin specific peptidase 15 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=981
Score = 46.6 bits (109), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 76/187 (40%), Gaps = 42/187 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNS-------VLKTLSEL 114
PG GL+NL T F IQ L PL Y L E+ +++ + K+ +EL
Sbjct 286 PGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAEL 345
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
++++++ + V+P F VG +F +Q D L A+LL+ LH D
Sbjct 346 IKQMWSGK--FSYVTPRAFKTQVG-RFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKK 402
Query 168 ----------QKDK-----------KTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ DK K SII D F G T E + + PF
Sbjct 403 PYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFC 462
Query 203 YLTLDLP 209
YLTL LP
Sbjct 463 YLTLPLP 469
> hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH4;
ubiquitin specific peptidase 15 (EC:3.4.19.12); K11835
ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=952
Score = 46.2 bits (108), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 76/187 (40%), Gaps = 42/187 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNS-------VLKTLSEL 114
PG GL+NL T F IQ L PL Y L E+ +++ + K+ +EL
Sbjct 257 PGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAEL 316
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
++++++ + V+P F VG +F +Q D L A+LL+ LH D
Sbjct 317 IKQMWSGK--FSYVTPRAFKTQVG-RFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKK 373
Query 168 ----------QKDK-----------KTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ DK K SII D F G T E + + PF
Sbjct 374 PYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFC 433
Query 203 YLTLDLP 209
YLTL LP
Sbjct 434 YLTLPLP 440
> cel:H34C03.2 hypothetical protein; K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=900
Score = 45.1 bits (105), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 10/113 (8%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLL----LDLSEKQ---KYNSVLKTLSEL 114
PG GL+NL T F A Q L + PLR Y L D++E + + + EL
Sbjct 272 PGACGLSNLGNTCFMASAFQCLSNMPPLREYFLANTYQNDINEDNPLGTHGHLAMAVGEL 331
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD 167
M+ +++ ++P +F +G + +F Q D L A++L+ LH D
Sbjct 332 MKGMWS--GDYASINPRKFKSIIG-QFAPRFNGYSQQDAHELMAYVLDGLHED 381
> dre:100329394 usp46, si:ch73-16a12.1; ubiquitin specific peptidase
46; K11842 ubiquitin carboxyl-terminal hydrolase 12/46
[EC:3.1.2.15]
Length=370
Score = 45.1 bits (105), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/139 (25%), Positives = 66/139 (47%), Gaps = 9/139 (6%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFK 125
GL N T + ++Q+L P R +L + +K+K N +L L++L I ++
Sbjct 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKVQQKKKEN-LLTCLADLFHSIATQKKKV 94
Query 126 GIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLN----VLHRDQKDKKTGGSIIHDC 181
G++ P +F+ + E+ F Q D +LLN +L ++K +K G + ++
Sbjct 95 GVIPPKKFISRLRKEN-DLFDNYMQQDAHEFLNYLLNTVADILQEERKQEKQNGRLKNN- 152
Query 182 FQGEVLVTDAQSEEGRKTP 200
G + TD + E+ + P
Sbjct 153 --GTAIATDTEPEQNKIDP 169
> hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin specific
peptidase 4 (proto-oncogene) (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=963
Score = 43.9 bits (102), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 46/206 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDL-SEKQKYN------SVLKTLSEL 114
PG GL NL T F +Q L PL +Y L + +E + N + + +EL
Sbjct 299 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 358
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
++++++ R+ V+P F VG +F +Q D L A+LL+ LH D
Sbjct 359 IKQMWSGRD--AHVAPRMFKTQVG-RFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK 415
Query 168 ---------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ + S+I D F G T E + + PF
Sbjct 416 PYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFC 475
Query 203 YLTLDLPPAPIFKDS-LDRNMIPTVP 227
YLTL P P+ KD ++ ++P P
Sbjct 476 YLTL---PLPLKKDRVMEVFLVPADP 498
> mmu:216835 Usp43, 9130017K11Rik, B930051C24, C630032K07Rik;
ubiquitin specific peptidase 43 (EC:3.4.19.12); K11856 ubiquitin
carboxyl-terminal hydrolase 43 [EC:3.1.2.15]
Length=1132
Score = 43.9 bits (102), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Query 54 SLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSE 113
S DGA PG GL N T F ++Q L L +L L V + L+
Sbjct 91 SGDGAR-PPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAA 149
Query 114 LMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKT 173
L+R ++ R + + EF AV + +F+ Q D L WLL+ +H D +
Sbjct 150 LVRALWTREYTPQLSA--EFKNAVS-KYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSAH 206
Query 174 G 174
G
Sbjct 207 G 207
> hsa:124739 USP43, FLJ30626; ubiquitin specific peptidase 43
(EC:3.4.19.12); K11856 ubiquitin carboxyl-terminal hydrolase
43 [EC:3.1.2.15]
Length=1123
Score = 43.5 bits (101), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Query 56 DGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELM 115
DGA PG GL N T F ++Q L L +L L V + L+ L+
Sbjct 93 DGAR-PPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRAEVTEQLAALV 151
Query 116 RKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKTG 174
R ++ R + + EF AV + +F+ Q D L WLL+ +H D + G
Sbjct 152 RALWTREYTPQLSA--EFKNAVS-KYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSSRG 207
> mmu:75083 Usp50, 1700086G18Rik, 4930511O11Rik; ubiquitin specific
peptidase 50 (EC:3.4.19.12)
Length=390
Score = 43.1 bits (100), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 28/172 (16%)
Query 63 GCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLL--LDLSEKQKYNSVLKTLSELMRKIFN 120
G GL NL T + I+Q LC++ PL Y L + K+ + V + LM ++
Sbjct 43 GVTGLRNLGNTCYMNAILQCLCSVSPLVEYFLSGKYITALKKDCSEVTTAFAYLMTDMWL 102
Query 121 RRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLH--------RDQKDKK 172
+ VSP FL AVG F Q D ++LN LH R +K+
Sbjct 103 GDS--DCVSPEIFLSAVG-SLYPAFLKKTQQDAQEFLIYVLNELHEALKKHCRRRVNEKR 159
Query 173 TG-----------GSIIHDCFQGE----VLVTDAQSEEGRKTPFLYLTLDLP 209
TG SII F+G+ + +S + F L+L +P
Sbjct 160 TGQSCCRKVPAQETSIITRLFEGQLSYSITCLKCESCTHKNEVFTILSLPIP 211
> hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3.4.19.12);
K11847 ubiquitin carboxyl-terminal hydrolase 19
[EC:3.1.2.15]
Length=1419
Score = 43.1 bits (100), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 71/187 (37%), Gaps = 40/187 (21%)
Query 61 LPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMR--KI 118
LPG GL NL T F +IQSL LR++ + YN+ L T L +
Sbjct 594 LPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAV 653
Query 119 FNRRNFKGIVSPHEF----LQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
R +KG + H F L+A+ +F Q D A+LL+ LH D
Sbjct 654 LLRALWKG--THHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNK 711
Query 168 ---------------------QKDKKTGGSIIHDCFQGEV---LVTDAQSEEGRK-TPFL 202
Q+ K S I D FQG+ LV ++ PFL
Sbjct 712 PYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFL 771
Query 203 YLTLDLP 209
YL + LP
Sbjct 772 YLPVPLP 778
> mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiquitin
specific peptidase 4 (proto-oncogene) (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=962
Score = 42.4 bits (98), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 46/206 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDL-SEKQKYN------SVLKTLSEL 114
PG GL NL T F +Q L PL Y L + +E + N + + +EL
Sbjct 299 PGLCGLGNLGNTCFMNSALQCLSNTAPLTEYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 358
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
++++++ R+ V+P F VG +F +Q D L A++L+ LH D
Sbjct 359 IKQMWSGRDTH--VAPRMFKTQVG-RFAPQFSGYQQQDSQELLAFILDGLHEDLNRVKKK 415
Query 168 ---------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ + S+I D F G T E + + PF
Sbjct 416 PYLEPKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFC 475
Query 203 YLTLDLPPAPIFKDS-LDRNMIPTVP 227
YLTL P P+ KD ++ ++P P
Sbjct 476 YLTL---PLPLKKDRIMEVFLVPADP 498
> hsa:64854 USP46, FLJ11850, FLJ12552, FLJ14283, FLJ39393; ubiquitin
specific peptidase 46 (EC:3.4.19.12); K11842 ubiquitin
carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15]
Length=359
Score = 41.6 bits (96), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 28/169 (16%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFK 125
GL N T + ++Q+L P R +L +K+K N +L L++L I ++
Sbjct 29 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKEN-LLTCLADLFHSIATQKKKV 87
Query 126 GIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLN----VLHRDQKDKKTGGSI---- 177
G++ P +F+ + E+ F Q D +LLN +L ++K +K G +
Sbjct 88 GVIPPKKFISRLRKEN-DLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGN 146
Query 178 --------------IHDCFQG----EVLVTDAQSEEGRKTPFLYLTLDL 208
+H+ FQG E + ++ + FL L++D+
Sbjct 147 MNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 195
> dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin specific
protease 4 (proto-oncogene); K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=1006
Score = 41.6 bits (96), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 56/212 (26%), Positives = 84/212 (39%), Gaps = 46/212 (21%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDL-SEKQKYN------SVLKTLSEL 114
PG GL+NL T F +Q L PL Y L +E + N + + ++L
Sbjct 313 PGLCGLSNLGNTCFMNSALQCLSNTPPLTEYFLEDRYEAEINRENPLGMRGEIAEAYADL 372
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRDQKDKKT- 173
+++++ R+ V+P F VG +F +Q D L A+LL+ LH D K
Sbjct 373 VKQMWLSRS--SYVAPRTFKTQVG-RFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK 429
Query 174 ---------------------------GGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
SII D F G T E + + PF
Sbjct 430 PYLALRDAEGRPDEIVAKEAWANHRLRNDSIIVDIFHGLFKSTLVCPECSKVSVTFDPFC 489
Query 203 YLTLDLPPAPIFKD-SLDRNMIPTVPIFDLLQ 233
YLTL P P+ KD +++ ++ T P F +Q
Sbjct 490 YLTL---PLPMKKDRTMEVYLVRTDPQFRAMQ 518
> xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (proto-oncogene);
K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=975
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 51/187 (27%), Positives = 71/187 (37%), Gaps = 42/187 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDL-SEKQKYN------SVLKTLSEL 114
PG GL+NL T F +Q L PL Y L + E + N + +EL
Sbjct 319 PGLCGLSNLGNTCFMNSALQCLSNSPPLTRYFLTDEYKKEINRENPLGMKGEIAVAYAEL 378
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
+R+I++ + V+P F VG +F +Q D L A+LL+ LH D
Sbjct 379 IRQIWSGDH--SYVAPRMFKTQVG-RFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK 435
Query 168 ---------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ + SII D F G T E + + PF
Sbjct 436 PYLELKDANGRPDSIVAAEAWENHLRRNNSIIVDIFHGLFKSTLVCPECHKVSVTFDPFC 495
Query 203 YLTLDLP 209
YLTL LP
Sbjct 496 YLTLPLP 502
> mmu:69727 Usp46, 1190009E20Rik, 2410018I08Rik, AI451644; ubiquitin
specific peptidase 46 (EC:3.4.19.12); K11842 ubiquitin
carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15]
Length=366
Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 28/169 (16%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFNRRNFK 125
GL N T + ++Q+L P R +L +K+K N +L L++L I ++
Sbjct 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKEN-LLTCLADLFHSIATQKKKV 94
Query 126 GIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLN----VLHRDQKDKKTGGSI---- 177
G++ P +F+ + E+ F Q D +LLN +L ++K +K G +
Sbjct 95 GVIPPKKFISRLRKEN-DLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGN 153
Query 178 --------------IHDCFQG----EVLVTDAQSEEGRKTPFLYLTLDL 208
+H+ FQG E + ++ + FL L++D+
Sbjct 154 MNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 202
> pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1332
Score = 41.2 bits (95), Expect = 0.003, Method: Composition-based stats.
Identities = 48/191 (25%), Positives = 76/191 (39%), Gaps = 52/191 (27%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVL-----------KTLSEL 114
GL NL T F +Q L I+ NY L Y++ + +TL+E+
Sbjct 313 GLINLGNTCFLNSSLQCLSKILKFSNYFLNGSFWNHINYSNPVGQHGRLAKAYYETLTEM 372
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
+ N+R+ +P +A+ E + +F +Q D L A+LL+ LH D
Sbjct 373 WK--INKRDCP--YAPKVLKEAIS-EKRDEFYGYQQHDSQELLAFLLDGLHEDLNLIRKK 427
Query 168 -----------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT----- 199
+ K+ SII D FQG+ + Q + +K
Sbjct 428 PYYEEKLQGGVDKLDVDVAEASWNRHKEINNSIIVDLFQGQYR-SRLQCPKCKKVSITFD 486
Query 200 PFLYLTLDLPP 210
PF+YL++ LPP
Sbjct 487 PFMYLSIPLPP 497
> mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin
specific peptidase 19 (EC:3.4.19.12); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1324
Score = 40.8 bits (94), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 51/185 (27%), Positives = 69/185 (37%), Gaps = 36/185 (19%)
Query 61 LPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMR--KI 118
LPG GL NL T F +IQSL LR++ + YN+ L T L +
Sbjct 536 LPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAV 595
Query 119 FNRRNFKGIVSPHE--FLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD--------- 167
R +KG + L+A+ +F Q D A+LL+ LH D
Sbjct 596 LLRALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPY 655
Query 168 -------------------QKDKKTGGSIIHDCFQGEV---LVTDAQSEEGRK-TPFLYL 204
Q+ K S I D FQG+ LV ++ PFLYL
Sbjct 656 TETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYL 715
Query 205 TLDLP 209
+ LP
Sbjct 716 PVPLP 720
> tpv:TP03_0714 hypothetical protein
Length=574
Score = 40.0 bits (92), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 0/39 (0%)
Query 38 TPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFF 76
+ EDV R SAE+ GKS+D P C G NN+ + ++
Sbjct 206 SAEDVVRYSAELNSGKSVDSKANYPKCCGCNNMCRNSYY 244
> dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiquitin
carboxyl-terminal hydrolase 31 [EC:3.1.2.15]
Length=1295
Score = 40.0 bits (92), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 50/134 (37%), Gaps = 35/134 (26%)
Query 59 DFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDL------SEKQKYNSVL---- 108
D +PG GL N T F I+Q L YL L EK K N V+
Sbjct 85 DKIPGVAGLKNHGNTCFMNAILQCLSNTELFAEYLALEQYRGDQTDDEKPKTNGVVGRKG 144
Query 109 --------KTLSELMRKIF-------NRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDP 153
+ LS L+R ++ + R+FK VS S ++R Q D
Sbjct 145 AQDRGEVTEQLSGLVRALWTFEYTPQHSRDFKNAVS----------RSAMQYRGNAQHDA 194
Query 154 LALFAWLLNVLHRD 167
WLL+ +H D
Sbjct 195 QEFLLWLLDRVHED 208
> dre:561425 novel protein similar to vertebrate ubiquitin specific
peptidase 19 (USP19); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1489
Score = 40.0 bits (92), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 17/177 (9%)
Query 36 TYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLL 95
T+TP S EV K PG GL NL T F +IQSL LR+Y
Sbjct 614 THTPPVGNERSEEVEEKKVCH-----PGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHD 668
Query 96 LDLSEKQKYNSVLKTLSELMR--KIFNRRNFKGIVSPHEF----LQAVGVESKKKFRIGE 149
+ N+ L T L + R +KG + H F L+A+ +F
Sbjct 669 RGFESEINCNNPLGTGGRLAIGFAVLLRALWKG--THHAFQPSKLKAIVASKASQFTGYA 726
Query 150 QSDPLALFAWLLNVLHRDQ---KDKKTGGSIIHDCFQGEVLVTDA-QSEEGRKTPFL 202
Q D A+LL+ LH D ++K ++ D Q EV+ +A Q + R F+
Sbjct 727 QHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRQDEVVAEEAWQRHKMRNDSFI 783
> dre:569700 usp16, si:ch211-238e22.5, si:dkey-121n8.2, wu:fc76b02,
wu:fc76b08; ubiquitin specific protease 16 (EC:3.4.19.12);
K11844 ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.1.2.15]
Length=815
Score = 39.3 bits (90), Expect = 0.015, Method: Composition-based stats.
Identities = 45/176 (25%), Positives = 77/176 (43%), Gaps = 35/176 (19%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLS------------- 112
GL+NL T FF ++QSL LR LL ++E++ S+ LS
Sbjct 209 GLSNLGNTCFFNAVVQSLSQTQYLRE--LLKQIAEEKSSFSITPALSSELDPLQIQLERP 266
Query 113 --------ELMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVL 164
+LM +I + KG+V+P E V + +F+ +Q D L +LL+ +
Sbjct 267 GSLTLAMCQLMNEI--QETKKGVVTPKELFTQV-CKKAPRFKGFQQQDSQELLRYLLDGM 323
Query 165 HRDQKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKTPFLYLTLDLPPAPIFKDSLDR 220
R ++ K+ I+ E L + ++ E +T + + AP K+ +DR
Sbjct 324 -RAEEAKRVNSGIL------EALKSSGKNFEAEQTKKIVKEYEKDGAP--KNFVDR 370
> dre:569679 usp3, fe50h06, wu:fe50h06; ubiquitin specific peptidase
3
Length=524
Score = 38.9 bits (89), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 50/214 (23%), Positives = 76/214 (35%), Gaps = 44/214 (20%)
Query 65 VGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLL--------DLSEKQKYNSVLK-----TL 111
GL NL T F I+QSL I Y L + ++ Y++ + +L
Sbjct 163 TGLRNLGNTCFMNAILQSLSNIQVFSCYFKELPSVALRSGKTAGRRMYHTRSQGDSSVSL 222
Query 112 SELMRKIFNR--RNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRDQK 169
E RK + + SP + + FR +Q D +LL+ LHR+ +
Sbjct 223 VEEFRKTLCSLWQGSQTAFSPDALFYVIW-KIMPSFRGYQQQDAHEFLRYLLDHLHREMQ 281
Query 170 DKKTGG----------------------------SIIHDCFQGEVLVTDAQSEEGRKTPF 201
K G S+ Q EV +E + PF
Sbjct 282 GNKNGSPSPPVTSDEPNHASESKCFINGTSTIVTSVFGGVLQNEVYCLICGTESRKFDPF 341
Query 202 LYLTLDLPPAPIFKDSLDRNMIPTVPIFDLLQKF 235
L L+LD+P K + D+ PT + D L+ F
Sbjct 342 LDLSLDIPNQFRIKTTKDQEPGPTCTLSDCLRSF 375
> dre:568334 ubiquitin specific protease 11-like
Length=658
Score = 38.9 bits (89), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 52/208 (25%), Positives = 80/208 (38%), Gaps = 47/208 (22%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLL-LDLSEKQKYN------SVLKTLSEL 114
PG GL NL T F +Q L PL Y L L L E N + + +++
Sbjct 290 PGVCGLTNLGNTCFMNSALQCLSNTPPLTEYFLKNLYLEELNFSNPLGMKGEIAEAYADV 349
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
++++++ R++ V P F VG +F +Q D L ++LL+ LH D
Sbjct 350 IKQMWSGRHYS--VVPRVFKTKVG-HFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKK 406
Query 168 ---------------------QKDKKTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFL 202
+ + S+I D F G T E + + PF
Sbjct 407 EYIELRDADGRPDQEVAEEAWRNHLRRNDSVIVDTFHGLFKSTLVCPECNKVSVTFDPFC 466
Query 203 YLTLDLPPA-----PIFKDSLDRNMIPT 225
YL++ LP + +F SLD PT
Sbjct 467 YLSVPLPVSKERVMEVFYVSLDPTAKPT 494
> hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15
[EC:3.1.2.15]
Length=963
Score = 38.5 bits (88), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 44/205 (21%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNS-------VLKTLSEL 114
PG GL NL T F +Q L + L Y L E+ + + + + ++L
Sbjct 306 PGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADL 365
Query 115 MRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD------- 167
+++ ++ + + IV PH F VG +F +Q D L ++LL+ LH D
Sbjct 366 VKQAWSGHH-RSIV-PHVFKNKVG-HFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKK 422
Query 168 ---------------------QKDKKTGGSIIHDCFQG----EVLVTDAQSEEGRKTPFL 202
Q K+ S+I D F G ++ D + PF
Sbjct 423 EYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFC 482
Query 203 YLTLDLPPAPIFKDSLDRNMIPTVP 227
YL++ LP + K L+ IP P
Sbjct 483 YLSVPLPIS--HKRVLEVFFIPMDP 505
> dre:100149276 ubiquitin specific protease 43-like; K11856 ubiquitin
carboxyl-terminal hydrolase 43 [EC:3.1.2.15]
Length=1163
Score = 38.5 bits (88), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 23/128 (17%)
Query 58 ADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRK 117
D PG +GL N T F ++Q L L YL L E+ K + ++ +R
Sbjct 109 GDKTPGVLGLKNHGNTCFMNAVVQCLSNTDLLAEYLGL----ERYKRDVCHNGINGFIRN 164
Query 118 IFNRRNFKGIVSPH-----------EFLQAVGVESK-------KKFRIGEQSDPLALFAW 159
N +N KG V+ ++ + E K +FR Q D L W
Sbjct 165 -GNGQNEKGEVTERLAVLVRALWTFQYTPQLSAEFKMTVSKYGAQFRGNSQHDALEFLLW 223
Query 160 LLNVLHRD 167
LL+ LH D
Sbjct 224 LLDRLHED 231
> ath:AT4G10570 UBP9; UBP9 (UBIQUITIN-SPECIFIC PROTEASE 9); cysteine-type
endopeptidase/ ubiquitin thiolesterase; K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=923
Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 61/238 (25%), Positives = 91/238 (38%), Gaps = 55/238 (23%)
Query 28 TFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTII 87
T ++L P T ED R S + GK G G GL+NL T F +Q L
Sbjct 273 TSNFSLFPRITSEDDGRDSLSIL-GKGEKG-----GLAGLSNLGNTCFMNSALQCLAHTP 326
Query 88 PLRNYLLLLDLSEKQKYNSVLKTLSE-------LMRKIFNRRNFKGIVSPHEFLQAVGVE 140
P+ Y L D S+ ++ L E L++K+++ + + V+P F +
Sbjct 327 PIVEY-FLQDYSDDINRDNPLGMCGELAIAFGDLLKKLWS--SGRNAVAPRAFKTKLA-R 382
Query 141 SKKKFRIGEQSDPLALFAWLLNVLHRD----------------------------QKDKK 172
+F Q D L A+LL+ LH D K
Sbjct 383 FAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYIELKDSDSRPDDEVAEELWNYHKA 442
Query 173 TGGSIIHDCFQGEVLVTDAQSEEGRKT----PFLYLTLDLPPAPIFKDSLDRNMIPTV 226
S+I D QG+ T G+ + PF+YL++ LP +L R+M TV
Sbjct 443 RNDSVIVDVCQGQYKSTLVCPVCGKISITFDPFMYLSVPLP------STLTRSMTITV 494
> mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;
ubiquitin specific peptidase 11 (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=921
Score = 38.1 bits (87), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 45/185 (24%), Positives = 68/185 (36%), Gaps = 38/185 (20%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLKTLSELMRKIFN- 120
PG GL NL T F +Q L + L Y L E+ + + L EL +
Sbjct 254 PGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADL 313
Query 121 -RRNFKGI---VSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD--------- 167
++ + G + P+ F VG +F +Q D L ++LL+ LH D
Sbjct 314 VKQTWSGYHRSIVPNVFKNKVG-HFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEY 372
Query 168 -------------------QKDKKTGGSIIHDCFQG----EVLVTDAQSEEGRKTPFLYL 204
Q K+ S+I D F G ++ D + PF YL
Sbjct 373 VELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYL 432
Query 205 TLDLP 209
++ LP
Sbjct 433 SVPLP 437
> ath:AT4G39910 ATUBP3; ATUBP3 (ARABIDOPSIS THALIANA UBIQUITIN-SPECIFIC
PROTEASE 3); ubiquitin-specific protease; K11842 ubiquitin
carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15]
Length=371
Score = 37.7 bits (86), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Query 66 GLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNS---VLKTLSELMRKIFNRR 122
G N T + ++Q+L +P R LL S K ++ ++ L++L +I +++
Sbjct 24 GFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADAEENLMTCLADLFSQISSQK 83
Query 123 NFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLN----VLHRDQKDKKT 173
G+++P F+Q + ++ + FR D +LLN +L ++ K KT
Sbjct 84 KKTGVIAPKRFVQRLKKQN-ELFRSYMHQDAHEFLNYLLNEVVDILEKEAKATKT 137
> ath:AT1G32850 UBP11; UBP11 (UBIQUITIN-SPECIFIC PROTEASE 11);
cysteine-type endopeptidase/ ubiquitin thiolesterase; K11835
ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=892
Score = 37.7 bits (86), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 53/202 (26%), Positives = 77/202 (38%), Gaps = 47/202 (23%)
Query 63 GCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYN------SVLKTLSELMR 116
G GL NL T F +Q L P+ Y L S+ N + EL+R
Sbjct 299 GLGGLQNLGNTCFMNSTLQCLAHTPPIVEYFLQDYRSDINAKNPLGMRGELAIAFGELLR 358
Query 117 KIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD--------- 167
K+++ + + V+P F + +F Q D + A+LL+ LH D
Sbjct 359 KLWS--SGQNTVAPRAFKTKLA-RFAPQFSGYNQHDSQEMLAFLLDGLHEDLNKVKRKPY 415
Query 168 --QKD-----------------KKTGGSIIHDCFQGEVLVTDAQSEEGRKT----PFLYL 204
KD K S+I D FQG+ T + G+ + PF+YL
Sbjct 416 IEAKDSDGRPDDEVAEEKWKYHKARNDSVIVDVFQGQYKSTLVCPDCGKISITFDPFMYL 475
Query 205 TLDLPPAPIFKDSLDRNMIPTV 226
+L LP S R+M TV
Sbjct 476 SLPLPS------SRTRSMTVTV 491
> mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific peptidase
2 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=619
Score = 37.4 bits (85), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query 63 GCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLL----LLDLSE-KQKYNSVLKTLSELMRK 117
G GL NL T F I+Q L LR+Y L + DL + ++++ ++L++
Sbjct 279 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHTALMEEFAKLIQT 338
Query 118 IFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD 167
I+ + +VSP EF + +F Q D +LL+ LH +
Sbjct 339 IWT-SSPNDVVSPSEFKTQI-QRYAPRFMGYNQQDAQEFLRFLLDGLHNE 386
> cel:ZK328.1 cyk-3; CYtoKinesis defect family member (cyk-3);
K11837 ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1178
Score = 37.0 bits (84), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 11/112 (9%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNSVLK--------TLSE 113
PG VGL N + IQ L + PL Y L D + K ++ + ++
Sbjct 567 PGAVGLVNYGNFCYRNAGIQCLARVSPLTQYFLDEDNLDAIKRGNLRRGDAAETTIEYAK 626
Query 114 LMRKIFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLH 165
L+R+++ + K ++P++F A+ + S F EQ D A+LL+ LH
Sbjct 627 LLREMWAAK--KKNIAPNDFNDAIRL-SSDMFECSEQHDCQEFVAFLLDQLH 675
> dre:563983 novel protein similar to vertebrate ubiquitin specific
protease 43 (USP43) (EC:3.1.2.15); K11856 ubiquitin carboxyl-terminal
hydrolase 43 [EC:3.1.2.15]
Length=1122
Score = 36.6 bits (83), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 32/127 (25%)
Query 62 PGCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLLL----LDLSEKQKYNSVLKT------- 110
PG GL N T F ++Q L L YL L +L+E+ + N ++K+
Sbjct 111 PGVQGLKNHGNTCFMNAVVQCLSNTELLAEYLGLEQYKYELNER-RINGMMKSEEVRGEV 169
Query 111 ---LSELMRKIFNRR-------NFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWL 160
L+ L+R ++ +FK +V+ + +F+ Q D L WL
Sbjct 170 TDKLASLVRALWTNDYTPQLSVDFKSVVAKY----------GSQFKGNAQHDALEFLLWL 219
Query 161 LNVLHRD 167
L+ +H D
Sbjct 220 LDCVHED 226
> hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC:3.4.19.12);
K11833 ubiquitin carboxyl-terminal hydrolase
2/21 [EC:3.1.2.15]
Length=605
Score = 36.6 bits (83), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query 63 GCVGLNNLSKTDFFAVIIQSLCTIIPLRNYLL----LLDLSE-KQKYNSVLKTLSELMRK 117
G GL NL T F I+Q L LR+Y L + DL + ++++ ++L++
Sbjct 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQT 324
Query 118 IFNRRNFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHRD 167
I+ + +VSP EF + +F Q D +LL+ LH +
Sbjct 325 IWT-SSPNDVVSPSEFKTQI-QRYAPRFVGYNQQDAQEFLRFLLDGLHNE 372
> ath:AT4G10590 UBP10; ubiquitin carboxyl-terminal hydrolase family
protein; K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=910
Score = 36.2 bits (82), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 55/238 (23%)
Query 28 TFKYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTII 87
T ++L P T ED S + GK G G GL+NL T F +Q L
Sbjct 272 TSNFSLFPRITSEDDGSNSLSIL-GKGEKG-----GLAGLSNLGNTCFMNSALQCLAHTP 325
Query 88 PLRNYLLLLDLSEKQKYNSVLKTLSE-------LMRKIFNRRNFKGIVSPHEFLQAVGVE 140
P+ Y L D S+ ++ L E L++K+++ + + V+P F +
Sbjct 326 PIVEY-FLQDYSDDINRDNPLGMCGELAIAFGDLLKKLWS--SGRNSVAPRAFKTKLA-R 381
Query 141 SKKKFRIGEQSDPLALFAWLLNVLHRD----------------------------QKDKK 172
+F Q D L A+LL+ LH D K
Sbjct 382 FAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYIELKDSDSRPDDEVAEELWNYHKA 441
Query 173 TGGSIIHDCFQGEVLVTDAQSEEGRKT----PFLYLTLDLPPAPIFKDSLDRNMIPTV 226
S+I D QG+ T G+ + PF+YL++ LP +L R+M TV
Sbjct 442 RNDSVIVDVCQGQYKSTLVCPACGKISITFDPFMYLSVPLP------STLTRSMTVTV 493
> hsa:57602 USP36, DUB1; ubiquitin specific peptidase 36 (EC:3.4.19.12);
K11855 ubiquitin carboxyl-terminal hydrolase 36/42
[EC:3.1.2.15]
Length=1123
Score = 36.2 bits (82), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 16/157 (10%)
Query 65 VGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSEKQKYNS--VLKTLSELMRKIFNRR 122
GL+NL T F IQ L PL NYLL + + S +L + + + F
Sbjct 122 AGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFA-- 179
Query 123 NFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHR------DQKDKKTGG- 175
N + P F++ + + + FR G Q D + ++ + + + D++T
Sbjct 180 NSGNAIKPVSFIRDL-KKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQAT 238
Query 176 SIIHDCFQG----EVLVTDAQSEEGRKTPFLYLTLDL 208
+++H F G V + +S P+L + L++
Sbjct 239 TLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEI 275
> mmu:84092 Usp8, AI574262, AW557536, Ubpy, mKIAA0055; ubiquitin
specific peptidase 8 (EC:3.4.19.12); K11839 ubiquitin carboxyl-terminal
hydrolase 8 [EC:3.1.2.15]
Length=1080
Score = 35.4 bits (80), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 6/143 (4%)
Query 30 KYNLNPTYTPEDVARLSAEVFYGKSLDGADFLPGCVGLNNLSKTDFFAVIIQSLCTIIPL 89
+ N P Y +++RLSA + P GL NL T + I+Q LC L
Sbjct 704 RENKPPCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL 763
Query 90 RNYLLLLDLSEKQKYNSVLKTLSELMRK--IFNRRNFKG---IVSPHEFLQAVGVESKKK 144
+Y + +++L E+ + I + + G +SP +F +G + +
Sbjct 764 ADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKVTIG-KINDQ 822
Query 145 FRIGEQSDPLALFAWLLNVLHRD 167
F Q D L +L++ LH D
Sbjct 823 FAGSSQQDSQELLLFLMDGLHED 845
> mmu:72344 Usp36, 2700002L06Rik, mKIAA1453; ubiquitin specific
peptidase 36 (EC:3.1.2.15 3.4.19.12); K11855 ubiquitin carboxyl-terminal
hydrolase 36/42 [EC:3.1.2.15]
Length=1098
Score = 35.4 bits (80), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 37/157 (23%), Positives = 66/157 (42%), Gaps = 16/157 (10%)
Query 65 VGLNNLSKTDFFAVIIQSLCTIIPLRNYLLLLDLSE--KQKYNSVLKTLSELMRKIFNRR 122
GL+NL T F IQ L PL NYLL + + Q +L + M + F
Sbjct 122 AGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHARSCHQGGFCMLCLMQNHMVQAFA-- 179
Query 123 NFKGIVSPHEFLQAVGVESKKKFRIGEQSDPLALFAWLLNVLHR------DQKDKKTGG- 175
N + P F++ + + + FR G Q D + ++ + + + D++T
Sbjct 180 NSGNAIKPVSFIRDL-KKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGYAKLDRQTQAT 238
Query 176 SIIHDCFQG----EVLVTDAQSEEGRKTPFLYLTLDL 208
+++H F G V + +S P+L + L++
Sbjct 239 TLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDIALEI 275
Lambda K H
0.321 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 8828802264
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40