bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_4916_orf1
Length=145
Score E
Sequences producing significant alignments: (Bits) Value
pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative... 127 8e-30
tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putat... 122 5e-28
dre:393962 usp20, MGC63661, im:7151955, zgc:63661; ubiquitin s... 80.5 2e-15
hsa:10868 USP20, KIAA1003, LSFR3A, VDU2; ubiquitin specific pe... 73.2 2e-13
mmu:74270 Usp20, 1700055M05Rik, AI467231, Vdu2; ubiquitin spec... 71.6 8e-13
dre:569679 usp3, fe50h06, wu:fe50h06; ubiquitin specific pepti... 71.2 1e-12
mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiqu... 69.7 3e-12
xla:100036785 usp3; ubiquitin specific peptidase 3 (EC:3.1.2.1... 67.4 1e-11
mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific pepti... 67.4 1e-11
mmu:235441 Usp3, AA409661, BC017156, MGC28886; ubiquitin speci... 66.6 3e-11
dre:564054 ubiquitin specific peptidase 2-like; K11833 ubiquit... 66.2 3e-11
dre:100002673 ubiquitin specific peptidase 2-like; K11833 ubiq... 66.2 3e-11
xla:100158436 usp20; ubiquitin specific peptidase 20 (EC:3.4.1... 65.9 5e-11
hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin spec... 65.5 5e-11
dre:100334088 ubiquitin specific peptidase 15-like 65.5 5e-11
hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.... 65.5 6e-11
sce:YMR223W UBP8; Ubiquitin-specific protease that is a compon... 65.1 8e-11
hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC... 64.7 9e-11
hsa:9960 USP3, MGC129878, MGC129879, SIH003, UBP; ubiquitin sp... 63.9 1e-10
mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;... 63.9 2e-10
mmu:170822 Usp33, 9830169D19Rik, AA409780, Vdu1; ubiquitin spe... 63.9 2e-10
hsa:23032 USP33, KIAA1097, MGC16868, VDU1; ubiquitin specific ... 63.5 2e-10
dre:494031 usp2a, zgc:92134; ubiquitin specific peptidase 2a (... 63.5 2e-10
dre:100329380 ubiquitin specific peptidase 15-like 61.6 7e-10
dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin spec... 60.8 1e-09
dre:563546 CG14619-like; K11833 ubiquitin carboxyl-terminal hy... 60.1 2e-09
ath:AT2G40930 UBP5; UBP5 (UBIQUITIN-SPECIFIC PROTEASE 5); ubiq... 60.1 2e-09
mmu:216835 Usp43, 9130017K11Rik, B930051C24, C630032K07Rik; ub... 60.1 3e-09
dre:406508 usp33, zgc:77308; ubiquitin specific peptidase 33 (... 59.7 3e-09
hsa:84669 USP32, NY-REN-60, USP10; ubiquitin specific peptidas... 59.7 3e-09
mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap1... 58.5 6e-09
hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH... 58.5 6e-09
xla:380243 usp8, MGC53905; ubiquitin specific peptidase 8 (EC:... 58.5 8e-09
hsa:124739 USP43, FLJ30626; ubiquitin specific peptidase 43 (E... 58.2 1e-08
mmu:237898 Usp32, 2900074J03Rik, 6430526O11Rik, AW045245; ubiq... 57.0 2e-08
hsa:9098 USP6, HRP1, TRE17, TRE2, Tre-2, USP6-short; ubiquitin... 57.0 2e-08
dre:561425 novel protein similar to vertebrate ubiquitin speci... 55.8 4e-08
dre:557981 ubiquitin specific peptidase 15-like; K11837 ubiqui... 55.8 4e-08
xla:495686 usp47; ubiquitin specific peptidase 47; K11857 ubiq... 55.8 5e-08
mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin sp... 55.5 5e-08
hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3... 55.1 7e-08
xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (pr... 55.1 8e-08
dre:565434 usp8, fb92h07, wu:fb92h07; ubiquitin specific pepti... 53.9 2e-07
mmu:30941 Usp21, ESTM28, Usp16, Usp23, W53272; ubiquitin speci... 53.1 3e-07
hsa:27005 USP21, MGC3394, USP16, USP23; ubiquitin specific pep... 53.1 3e-07
mmu:76179 Usp31, 6330567E21Rik, mKIAA1203; ubiquitin specific ... 53.1 3e-07
ath:AT5G22030 UBP8; UBP8 (UBIQUITIN-SPECIFIC PROTEASE 8); ubiq... 53.1 3e-07
hsa:57478 USP31, KIAA1203; ubiquitin specific peptidase 31 (EC... 53.1 3e-07
cel:T05H10.1 hypothetical protein; K11857 ubiquitin carboxyl-t... 53.1 3e-07
dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiq... 52.8 3e-07
> pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1332
Score = 127 bits (320), Expect = 8e-30, Method: Composition-based stats.
Identities = 56/124 (45%), Positives = 84/124 (67%), Gaps = 0/124 (0%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF+N NRW R+K ++ V +P+K EYL+M +IL GL+ + + +P + P YELI VN
Sbjct 1192 LKRFNNTNRWLRTKIDSYVYYPHKDKEYLNMAPYILQDGLKHMTKLNPKYAPLYELIGVN 1251
Query 61 VHSGELGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMRRI 120
H+G L GGHY+AY K+ QWY FNDSCV+ + E + ++ +AY+L Y+L S + +
Sbjct 1252 CHTGSLCGGHYFAYVKLNDQWYNFNDSCVSTIDEAEVNTKNAYLLFYQLISHKNEKFSGY 1311
Query 121 AKVK 124
A+ +
Sbjct 1312 AQTR 1315
> tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1100
Score = 122 bits (305), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 51/81 (62%), Positives = 63/81 (77%), Gaps = 0/81 (0%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRFHN+ R++RSK T+V FPYK G+YLDM +ILP LE + +D P YEL+AVN
Sbjct 1020 LKRFHNIGRFTRSKIGTKVTFPYKAGDYLDMTPYILPESLEMMHAKDQGLAPLYELVAVN 1079
Query 61 VHSGELGGGHYYAYTKIRGQW 81
VHSGELGGGHY+AY K+RG+W
Sbjct 1080 VHSGELGGGHYFAYAKLRGRW 1100
> dre:393962 usp20, MGC63661, im:7151955, zgc:63661; ubiquitin
specific protease 20 (EC:3.1.2.15 3.4.19.12); K11848 ubiquitin
carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15]
Length=913
Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 55/127 (43%), Positives = 71/127 (55%), Gaps = 16/127 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S K N+ V FP E LD+K F L +E PS Y+L++V
Sbjct 586 LKRFRHEVMYSF-KINSHVSFPL---EGLDLKPF--------LAKESPSQITTYDLLSVI 633
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G G GHY AY + I GQWYEF+D VT VHE +A+AY+L Y R S E+S+R
Sbjct 634 CHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNAEAYVLFY--RKSSEESVR 691
Query 119 RIAKVKA 125
+V A
Sbjct 692 ERQRVVA 698
> hsa:10868 USP20, KIAA1003, LSFR3A, VDU2; ubiquitin specific
peptidase 20 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal
hydrolase 20/33 [EC:3.1.2.15]
Length=914
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 55/134 (41%), Positives = 72/134 (53%), Gaps = 18/134 (13%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S K N+ V FP E LD++ F L +E S Y+L++V
Sbjct 586 LKRFRHEVMYS-FKINSHVSFPL---EGLDLRPF--------LAKECTSQITTYDLLSVI 633
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G G GHY AY + I GQWYEF+D VT VHE +A+ Y+L Y R S E++MR
Sbjct 634 CHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNAEGYVLFY--RKSSEEAMR 691
Query 119 RIAKVK--AANRIP 130
+V AA R P
Sbjct 692 ERQQVVSLAAMREP 705
> mmu:74270 Usp20, 1700055M05Rik, AI467231, Vdu2; ubiquitin specific
peptidase 20 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal
hydrolase 20/33 [EC:3.1.2.15]
Length=916
Score = 71.6 bits (174), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 54/134 (40%), Positives = 72/134 (53%), Gaps = 18/134 (13%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S K ++ V FP E LD++ F L +E S Y+L++V
Sbjct 588 LKRFRHEVMYSF-KVSSHVSFPL---EGLDLRPF--------LAKECTSQVTTYDLLSVI 635
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G G GHY AY + I GQWYEF+D VT VHE + +AY+L Y R S E++MR
Sbjct 636 CHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNVEAYVLFY--RKSSEEAMR 693
Query 119 RIAKVK--AANRIP 130
+V AA R P
Sbjct 694 ERQQVVSLAAMREP 707
> dre:569679 usp3, fe50h06, wu:fe50h06; ubiquitin specific peptidase
3
Length=524
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 52/120 (43%), Positives = 64/120 (53%), Gaps = 21/120 (17%)
Query 1 LKRFHNVNRWS---RSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ--YE 55
LKRFH W+ R+K +T V FP LDMK ++L E + S + Y+
Sbjct 415 LKRFH----WTAFLRNKVDTYVEFPMCG---LDMKSYLL--------EPENSLPERCLYD 459
Query 56 LIAVNVHSGE-LGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSRE 114
L AV VH G +G GHY AY + GQWY FNDS VT V E+ A AY+L Y S RE
Sbjct 460 LAAVVVHHGSGIGSGHYTAYGRHEGQWYHFNDSTVTLVSEEAVLKAKAYILFYTEHSDRE 519
> mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiquitin
specific peptidase 4 (proto-oncogene) (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=962
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 48/130 (36%), Positives = 68/130 (52%), Gaps = 17/130 (13%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNP-QYELIAV 59
LKRF + NR+ R K +T V FP + L+M +F+ D S P Y+LIAV
Sbjct 824 LKRF-SYNRYWRDKLDTVVEFPVRA---LNMSEFVC----------DRSARPYVYDLIAV 869
Query 60 NVHSGELGGGHYYAYTKIR--GQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSM 117
+ H G +G GHY AY K R G+WY F+DS V+ ED+ + AY+L Y+ R S
Sbjct 870 SNHYGAMGVGHYTAYAKNRLNGKWYYFDDSSVSLASEDQIVTKAAYVLFYQRRDDECSST 929
Query 118 RRIAKVKAAN 127
+ ++
Sbjct 930 SSLGSFPGSD 939
> xla:100036785 usp3; ubiquitin specific peptidase 3 (EC:3.1.2.15);
K11986 ubiquitin carboxyl-terminal hydrolase 3 [EC:3.1.2.15]
Length=522
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/114 (41%), Positives = 60/114 (52%), Gaps = 23/114 (20%)
Query 1 LKRFHNVNRWS---RSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ---Y 54
LKRFH W+ R+K +T V FP + LDMK F+L E + P+ Y
Sbjct 413 LKRFH----WTAYLRNKVDTYVDFPLRG---LDMKSFLL---------EPENIGPESCLY 456
Query 55 ELIAVNVHSGE-LGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTY 107
+L AV VH G +G GHY AY G+W+ FNDS VT E+ A AY+L Y
Sbjct 457 DLEAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTEEETVAKAKAYILFY 510
> mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific peptidase
2 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=619
Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 43/113 (38%), Positives = 61/113 (53%), Gaps = 16/113 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF +R SK T V FP + LD+++F + + + Y L AV+
Sbjct 516 LKRFSE-SRIRTSKLTTFVNFPLRD---LDLREF----------ASENTNHAVYNLYAVS 561
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
HSG GGHY AY + + G+W+ FNDS VT + + ++DAY+L YEL S
Sbjct 562 NHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELAS 614
> mmu:235441 Usp3, AA409661, BC017156, MGC28886; ubiquitin specific
peptidase 3 (EC:3.4.19.12); K11986 ubiquitin carboxyl-terminal
hydrolase 3 [EC:3.1.2.15]
Length=520
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 47/117 (40%), Positives = 61/117 (52%), Gaps = 17/117 (14%)
Query 1 LKRFHNVNRWS---RSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELI 57
LKRFH W+ R+K +T V FP + LDMK ++L E + Y+L
Sbjct 411 LKRFH----WTAYLRNKVDTYVQFPLRG---LDMKCYLLEP------ENSGPDSCLYDLA 457
Query 58 AVNVHSGE-LGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSR 113
AV VH G +G GHY AY G+W+ FNDS VT E+ A AY+L Y R +R
Sbjct 458 AVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQAR 514
> dre:564054 ubiquitin specific peptidase 2-like; K11833 ubiquitin
carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
Length=398
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 45/114 (39%), Positives = 60/114 (52%), Gaps = 16/114 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF R SK +T V FP K LD+++F D S N Y L AV+
Sbjct 296 LKRFSEC-RVRTSKLSTFVNFPLKE---LDLREF----------ASDNSVNAVYNLYAVS 341
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSS 112
H+G GGHY AY + G+WY +NDS V+ + + S+DAY+L YE +S
Sbjct 342 NHTGTSLGGHYTAYCRSPCTGEWYTYNDSRVSPMSSSQVCSSDAYVLFYECATS 395
> dre:100002673 ubiquitin specific peptidase 2-like; K11833 ubiquitin
carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
Length=398
Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 45/114 (39%), Positives = 60/114 (52%), Gaps = 16/114 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF R SK +T V FP K LD+++F D S N Y L AV+
Sbjct 296 LKRFSEC-RVRTSKLSTFVNFPLKE---LDLREF----------ASDNSVNAVYNLYAVS 341
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSS 112
H+G GGHY AY + G+WY +NDS V+ + + S+DAY+L YE +S
Sbjct 342 NHTGTSLGGHYTAYCRSPCTGEWYTYNDSRVSPMSSSQVCSSDAYVLFYECATS 395
> xla:100158436 usp20; ubiquitin specific peptidase 20 (EC:3.4.19.12);
K11848 ubiquitin carboxyl-terminal hydrolase 20/33
[EC:3.1.2.15]
Length=840
Score = 65.9 bits (159), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 66/125 (52%), Gaps = 16/125 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S K + V FP E L+++ F L +E S Y+L+AV
Sbjct 512 LKRFRHEVMYSF-KIGSHVSFPL---EGLNLRPF--------LAKECVSRITTYDLLAVI 559
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G GHY +Y + I GQWYEF+D VT VHE +A+AY+L Y R S E++ R
Sbjct 560 CHHGSASSGHYISYCQNVINGQWYEFDDQYVTEVHETVVQNAEAYVLFY--RKSSEEAER 617
Query 119 RIAKV 123
KV
Sbjct 618 ERQKV 622
> hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin specific
peptidase 4 (proto-oncogene) (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=963
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 45/113 (39%), Positives = 64/113 (56%), Gaps = 17/113 (15%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNP-QYELIAV 59
LKRF + NR+ R K +T V FP + L+M +F+ + S P Y+LIAV
Sbjct 825 LKRF-SYNRYWRDKLDTVVEFPIRG---LNMSEFVC----------NLSARPYVYDLIAV 870
Query 60 NVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELR 110
+ H G +G GHY AY K + G+WY F+DS V+ ED+ + AY+L Y+ R
Sbjct 871 SNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRR 923
> dre:100334088 ubiquitin specific peptidase 15-like
Length=391
Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 46/121 (38%), Positives = 66/121 (54%), Gaps = 15/121 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + ++SR K +T V FP + LD F+L + P Y+LI+V+
Sbjct 247 LKRF-SYTKYSREKLDTIVEFPLRD---LDFSGFLLKKTVNSTEPPCP-----YDLISVS 297
Query 61 VHSGELGGGHY--YAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G L GHY YA K GQWY F+DS VT E++ ++ AY+L Y+ R+D +R
Sbjct 298 NHYGGLRDGHYTSYARNKDNGQWYYFDDSKVTYAREEQIVTSAAYLLFYQ----RQDKIR 353
Query 119 R 119
+
Sbjct 354 Q 354
> hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15
[EC:3.1.2.15]
Length=963
Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 45/122 (36%), Positives = 71/122 (58%), Gaps = 15/122 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + ++SR K +T V FP + LD +F++ + E +P +Y+LIAV+
Sbjct 828 LKRF-SYTKFSREKLDTLVEFPIRD---LDFSEFVI----QPQNESNPELY-KYDLIAVS 878
Query 61 VHSGELGGGHY--YAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G + GHY +A K GQW+ F+D+ V+ V+E++ S AY+L Y+ R+D R
Sbjct 879 NHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQ----RQDVAR 934
Query 119 RI 120
R+
Sbjct 935 RL 936
> sce:YMR223W UBP8; Ubiquitin-specific protease that is a component
of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation
complex; required for SAGA-mediated deubiquitination of histone
H2B (EC:3.1.2.15); K11366 ubiquitin carboxyl-terminal
hydrolase 22/27/51 [EC:3.1.2.15]
Length=471
Score = 65.1 bits (157), Expect = 8e-11, Method: Composition-based stats.
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 5/111 (4%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF ++ S K + + FP YL+MK + ++ E + YELI +
Sbjct 362 LKRFEHLLNGSNRKLDDFIEFP----TYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIV 417
Query 61 VHSGELGGGHYYAYTKIRG-QWYEFNDSCVTAVHEDKCHSADAYMLTYELR 110
H G + GHY A+ KI G QW++FNDS V+++ +++ AY+L Y +R
Sbjct 418 SHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
> hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC:3.4.19.12);
K11833 ubiquitin carboxyl-terminal hydrolase
2/21 [EC:3.1.2.15]
Length=605
Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 16/113 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF +R SK T V FP + LD+++F + + + Y L AV+
Sbjct 502 LKRFSE-SRIRTSKLTTFVNFPLRD---LDLREF----------ASENTNHAVYNLYAVS 547
Query 61 VHSGELGGGHYYAYTKI--RGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
HSG GGHY AY + G+W+ FNDS VT + + ++DAY+L YEL S
Sbjct 548 NHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELAS 600
> hsa:9960 USP3, MGC129878, MGC129879, SIH003, UBP; ubiquitin
specific peptidase 3 (EC:3.4.19.12); K11986 ubiquitin carboxyl-terminal
hydrolase 3 [EC:3.1.2.15]
Length=520
Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 46/114 (40%), Positives = 60/114 (52%), Gaps = 23/114 (20%)
Query 1 LKRFHNVNRWS---RSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ---Y 54
LKRFH W+ R+K +T V FP + LDMK ++L E + P+ Y
Sbjct 411 LKRFH----WTAYLRNKVDTYVEFPLRG---LDMKCYLL---------EPENSGPESCLY 454
Query 55 ELIAVNVHSGE-LGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTY 107
+L AV VH G +G GHY AY G+W+ FNDS VT E+ A AY+L Y
Sbjct 455 DLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVKAKAYILFY 508
> mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;
ubiquitin specific peptidase 11 (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=921
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 45/129 (34%), Positives = 74/129 (57%), Gaps = 15/129 (11%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + ++ SR K +T V FP + LD +F++ + E P +Y+LIAV+
Sbjct 787 LKRF-SFSKISREKLDTLVQFPIRD---LDFSEFVI----KPKNESSPDLY-KYDLIAVS 837
Query 61 VHSGELGGGHY--YAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G + GHY +A K GQW+ F+D+ V+ V+E++ S AY+L Y+ R+D R
Sbjct 838 NHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQ----RQDVGR 893
Query 119 RIAKVKAAN 127
R ++ +++
Sbjct 894 RQSQTSSSD 902
> mmu:170822 Usp33, 9830169D19Rik, AA409780, Vdu1; ubiquitin specific
peptidase 33 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal
hydrolase 20/33 [EC:3.1.2.15]
Length=897
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 68/128 (53%), Gaps = 19/128 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S +K +T V FP E LD++ F L ++ P+ Y+L++V
Sbjct 575 LKRFRHELMFS-TKISTHVSFPL---EGLDLQPF--------LAKDSPAQIVTYDLLSVI 622
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSM- 117
H G GHY AY + + WYEF+D VT V E +A+AY+L Y R S E++
Sbjct 623 CHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFY--RKSSEEAQK 680
Query 118 --RRIAKV 123
RRI+ +
Sbjct 681 ERRRISNL 688
> hsa:23032 USP33, KIAA1097, MGC16868, VDU1; ubiquitin specific
peptidase 33 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal
hydrolase 20/33 [EC:3.1.2.15]
Length=942
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 68/128 (53%), Gaps = 19/128 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S +K +T V FP E LD++ F L ++ P+ Y+L++V
Sbjct 616 LKRFRHELMFS-TKISTHVSFPL---EGLDLQPF--------LAKDSPAQIVTYDLLSVI 663
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSM- 117
H G GHY AY + + WYEF+D VT V E +A+AY+L Y R S E++
Sbjct 664 CHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFY--RKSSEEAQK 721
Query 118 --RRIAKV 123
RRI+ +
Sbjct 722 ERRRISNL 729
> dre:494031 usp2a, zgc:92134; ubiquitin specific peptidase 2a
(EC:3.1.2.15); K11833 ubiquitin carboxyl-terminal hydrolase
2/21 [EC:3.1.2.15]
Length=391
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 45/110 (40%), Positives = 57/110 (51%), Gaps = 16/110 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF R SK +T V FP K LD+++F D S + Y L AV+
Sbjct 292 LKRFSEA-RIRTSKLSTFVNFPMKD---LDLREF----------ASDRSSSAVYNLYAVS 337
Query 61 VHSGELGGGHYYAY--TKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYE 108
HSG GGHY AY G+WY +NDS VT + + S+DAY+L YE
Sbjct 338 NHSGTTMGGHYTAYCCNPENGEWYTYNDSRVTPMSASQVRSSDAYVLFYE 387
> dre:100329380 ubiquitin specific peptidase 15-like
Length=317
Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 53/138 (38%), Positives = 74/138 (53%), Gaps = 30/138 (21%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ-----YE 55
LKRF + +R+ R K +T V FP + LDM +F++ NP Y+
Sbjct 168 LKRF-SYSRYMRDKLDTLVEFPLRD---LDMSEFLI--------------NPHAGVCLYD 209
Query 56 LIAVNVHSGELGGGHYYAYTKI--RGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSR 113
LIAV+ H G +GGGHY AY K GQWY F+DS V+ E++ S AY+L Y+ R
Sbjct 210 LIAVSNHYGGMGGGHYTAYAKNVEDGQWYSFDDSSVSPASEEQIVSKAAYVLFYQ----R 265
Query 114 EDSMRRIAKVKAANRIPP 131
+D++R A +R PP
Sbjct 266 QDTVRGTGYF-ALDREPP 282
> dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin specific
protease 4 (proto-oncogene); K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=1006
Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/115 (41%), Positives = 66/115 (57%), Gaps = 17/115 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ-YELIAV 59
LKRF + NR R K +T V FP + L+M +F+ DP +P Y+LIAV
Sbjct 880 LKRF-SYNRCWRDKLDTVVDFPIRD---LNMSEFVC----------DPKADPYIYDLIAV 925
Query 60 NVHSGELGGGHYYAY--TKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSS 112
+ H G +GGGHY AY K G+WY F+DS V+A ED+ + AY+L Y+ R +
Sbjct 926 SNHYGGMGGGHYTAYGKNKADGKWYYFDDSSVSAATEDQIVTKAAYVLFYQRRDA 980
> dre:563546 CG14619-like; K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=404
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 43/111 (38%), Positives = 57/111 (51%), Gaps = 14/111 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
L RF ++R+S SK+ V FP LD+ GL + P Y+L AV
Sbjct 302 LNRFA-MSRFSISKSTVPVSFPLTA---LDL-------GLFGPVDCGPVL---YDLYAVC 347
Query 61 VHSGELGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
HSG + GHY A + W +NDSCV A+ E+K S AY+L YEL+S
Sbjct 348 NHSGTVNMGHYTAACREEEGWCFYNDSCVDAISEEKLQSNQAYVLFYELKS 398
> ath:AT2G40930 UBP5; UBP5 (UBIQUITIN-SPECIFIC PROTEASE 5); ubiquitin-specific
protease; K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=924
Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 16/114 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQ-YELIAV 59
LKRF + +R + K T V FP LD+ K++ L Q PQ YEL A+
Sbjct 817 LKRF-SYSRSMKHKLETFVNFPIHD---LDLTKYVANKNLSQ---------PQLYELYAL 863
Query 60 NVHSGELGGGHYYAYTKI--RGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
H G +G GHY A+ K+ +WY F+DS ++ ++ED S AY+L Y +S
Sbjct 864 TNHYGGMGSGHYTAHIKLLDDSRWYNFDDSHISHINEDDVKSGAAYVLFYRRKS 917
> mmu:216835 Usp43, 9130017K11Rik, B930051C24, C630032K07Rik;
ubiquitin specific peptidase 43 (EC:3.4.19.12); K11856 ubiquitin
carboxyl-terminal hydrolase 43 [EC:3.1.2.15]
Length=1132
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 20/128 (15%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFIL---------PGGLEQLREED--PS 49
LKRF V R+K +T V FP L+M + PG ++ P+
Sbjct 589 LKRFCQVGE-RRNKLSTLVKFPLSG---LNMAPHVARRSTNSKAGPGPWSSWKQPICLPT 644
Query 50 FNPQ---YELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYM 104
P Y+L AV H G L GGHY AY + + GQWY ++DS V A+ ED+ ++ AY+
Sbjct 645 TYPLDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSTVEALREDEVNTRGAYI 704
Query 105 LTYELRSS 112
L Y+ R+S
Sbjct 705 LFYQKRNS 712
> dre:406508 usp33, zgc:77308; ubiquitin specific peptidase 33
(EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal hydrolase
20/33 [EC:3.1.2.15]
Length=897
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 14/121 (11%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +S +K T V FP E L+M+ F L ++ + Y+L++V
Sbjct 571 LKRFRHELMFS-TKIGTHVSFPL---EGLEMQPF--------LAKDSSALTTTYDLLSVI 618
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSMR 118
H G GHY AY + + WYEF+D VT V E +A+AY+L Y+ + R
Sbjct 619 CHHGTASSGHYIAYCRNELNQLWYEFDDQSVTEVSESCVQNAEAYVLFYKKSNDETQKER 678
Query 119 R 119
R
Sbjct 679 R 679
> hsa:84669 USP32, NY-REN-60, USP10; ubiquitin specific peptidase
32 (EC:3.4.19.12); K11837 ubiquitin carboxyl-terminal hydrolase
6/32 [EC:3.1.2.15]
Length=1604
Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query 46 EDPSFNPQYELIAVNVHSGELGGGHYYAYTK-IRGQWYEFNDSCVTAVHEDKCHSADAYM 104
ED P Y L A++ HSG LGGGHY Y K +WY +NDS +H D+ + AY+
Sbjct 1502 EDTRIKPIYNLYAISCHSGILGGGHYVTYAKNPNCKWYCYNDSSCKELHPDEIDTDSAYI 1561
Query 105 LTYE 108
L YE
Sbjct 1562 LFYE 1565
> mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap18,
mKIAA0529; ubiquitin specific peptidase 15 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=981
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 52/142 (36%), Positives = 74/142 (52%), Gaps = 30/142 (21%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNP-QYELIAV 59
LKRF + +R+ R K +T V FP LDM +F++ +P+ P +Y LIAV
Sbjct 835 LKRF-SYSRYMRDKLDTLVDFPISD---LDMSEFLI----------NPNAGPCRYNLIAV 880
Query 60 NVHSGELGGGHYYAYTKIR--GQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSM 117
+ H G +GGGHY A+ K + G+WY F+DS V+ ED+ S AY+L Y+ R+D+
Sbjct 881 SNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQ----RQDTF 936
Query 118 ---------RRIAKVKAANRIP 130
R AA IP
Sbjct 937 SGTGFFPLDRETKGASAATGIP 958
> hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH4;
ubiquitin specific peptidase 15 (EC:3.4.19.12); K11835
ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=952
Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 52/142 (36%), Positives = 74/142 (52%), Gaps = 30/142 (21%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNP-QYELIAV 59
LKRF + +R+ R K +T V FP LDM +F++ +P+ P +Y LIAV
Sbjct 806 LKRF-SYSRYMRDKLDTLVDFPIND---LDMSEFLI----------NPNAGPCRYNLIAV 851
Query 60 NVHSGELGGGHYYAYTKIR--GQWYEFNDSCVTAVHEDKCHSADAYMLTYELRSSREDSM 117
+ H G +GGGHY A+ K + G+WY F+DS V+ ED+ S AY+L Y+ R+D+
Sbjct 852 SNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQ----RQDTF 907
Query 118 ---------RRIAKVKAANRIP 130
R AA IP
Sbjct 908 SGTGFFPLDRETKGASAATGIP 929
> xla:380243 usp8, MGC53905; ubiquitin specific peptidase 8 (EC:3.1.2.15);
K11839 ubiquitin carboxyl-terminal hydrolase 8
[EC:3.1.2.15]
Length=1063
Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 16/109 (14%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF RW R K V FP E LD+ +++ P + +Y L V+
Sbjct 957 LKRFSFEGRW-RQKLQAYVDFPL---ESLDLSPYVI----------GPKSSKKYNLFGVS 1002
Query 61 VHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTY 107
H G L GGHY AY K ++ +W++F+D V+ + ++ AYML Y
Sbjct 1003 NHYGGLDGGHYTAYCKNALKQRWFKFDDHDVSDISVSSVKTSAAYMLFY 1051
> hsa:124739 USP43, FLJ30626; ubiquitin specific peptidase 43
(EC:3.4.19.12); K11856 ubiquitin carboxyl-terminal hydrolase
43 [EC:3.1.2.15]
Length=1123
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 28/61 (45%), Positives = 40/61 (65%), Gaps = 2/61 (3%)
Query 54 YELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
Y+L AV H G L GGHY AY + + GQWY ++DS V + ED+ ++ AY+L Y+ R+
Sbjct 652 YDLYAVCNHHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRN 711
Query 112 S 112
S
Sbjct 712 S 712
> mmu:237898 Usp32, 2900074J03Rik, 6430526O11Rik, AW045245; ubiquitin
specific peptidase 32 (EC:3.1.2.15); K11837 ubiquitin
carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1604
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 31/66 (46%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Query 44 REEDPSFNPQYELIAVNVHSGELGGGHYYAYTK-IRGQWYEFNDSCVTAVHEDKCHSADA 102
REE S P Y L A++ HSG LGGGHY Y K +WY +NDS +H D+ + A
Sbjct 1501 REETHS-KPIYNLYAISCHSGILGGGHYVTYAKNPNCKWYCYNDSSCKELHPDEIDTDSA 1559
Query 103 YMLTYE 108
Y+L YE
Sbjct 1560 YILFYE 1565
> hsa:9098 USP6, HRP1, TRE17, TRE2, Tre-2, USP6-short; ubiquitin
specific peptidase 6 (Tre-2 oncogene) (EC:3.4.19.12); K11837
ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1406
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 28/64 (43%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query 46 EDPSFNPQYELIAVNVHSGELGGGHYYAYTK-IRGQWYEFNDSCVTAVHEDKCHSADAYM 104
ED P Y L A++ HSG L GGHY Y K +WY +NDS +H D+ + AY+
Sbjct 1304 EDTHIKPIYNLYAISCHSGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYI 1363
Query 105 LTYE 108
L YE
Sbjct 1364 LFYE 1367
> dre:561425 novel protein similar to vertebrate ubiquitin specific
peptidase 19 (USP19); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1489
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 43/123 (34%), Positives = 58/123 (47%), Gaps = 22/123 (17%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFIL--PGGLEQLREEDPSFNPQYELIA 58
LKRF + R K N V FP + LD+ KF + G ++Q P Y+L A
Sbjct 1257 LKRFSFRSFIWRDKINDMVDFPVRN---LDLSKFCIGHKGDIQQ--------PPIYDLYA 1305
Query 59 VNVHSGELGGGHYYAYTKIRGQ---------WYEFNDSCVTAVHEDKCHSADAYMLTYEL 109
V H G + GGHY AY ++ W F+DS VT V E + + AY+L Y
Sbjct 1306 VINHYGGMIGGHYTAYARLPSDKNSQLSDVGWRLFDDSTVTTVEESQVVTRYAYVLFYRR 1365
Query 110 RSS 112
R+S
Sbjct 1366 RNS 1368
> dre:557981 ubiquitin specific peptidase 15-like; K11837 ubiquitin
carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1675
Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query 47 DPSFNPQYELIAVNVHSGELGGGHYYAYTKIRGQ-WYEFNDSCVTAVHEDKCHSADAYML 105
D Y L A++ HSG +GGGHY Y K + WY +NDS VH D+ + AY+L
Sbjct 1574 DICLESLYNLYAISCHSGIMGGGHYVTYAKNPNEKWYCYNDSSCKEVHSDEIDTDSAYIL 1633
Query 106 TYE 108
YE
Sbjct 1634 FYE 1636
> xla:495686 usp47; ubiquitin specific peptidase 47; K11857 ubiquitin
carboxyl-terminal hydrolase 47 [EC:3.1.2.15]
Length=1350
Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 26/114 (22%)
Query 40 LEQLREEDPSFNPQYELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDK- 96
+E+L + N YEL +V VHSG GGHYYA K GQWY FND V+ + ++
Sbjct 457 IEKLNKSVAEKNSLYELFSVMVHSGSAAGGHYYACIKSFADGQWYSFNDQHVSRITQEDI 516
Query 97 ------------------CHSADAYMLTYELRSSREDSMRRIAKVKAANRIPPH 132
S +AYML Y L++ R A+ A+ P H
Sbjct 517 KKTYGGATGNRGYYSSAFASSTNAYMLMYRLKNP-----ARNAQFLEASEFPEH 565
> mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin
specific peptidase 19 (EC:3.4.19.12); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1324
Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 20/121 (16%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + R K N V FP + LD+ KF + EQL P Y+L AV
Sbjct 1150 LKRFSFRSFIWRDKINDLVEFPVRN---LDLSKFCIGQKEEQL--------PSYDLYAVI 1198
Query 61 VHSGELGGGHYYAYTKIRGQ---------WYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
H G + GGHY A ++ W F+DS VT V E + + AY+L Y R+
Sbjct 1199 NHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRN 1258
Query 112 S 112
S
Sbjct 1259 S 1259
> hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3.4.19.12);
K11847 ubiquitin carboxyl-terminal hydrolase 19
[EC:3.1.2.15]
Length=1419
Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 20/121 (16%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + R K N V FP + LD+ KF + EQL P Y+L AV
Sbjct 1208 LKRFSFRSFIWRDKINDLVEFPVRN---LDLSKFCIGQKEEQL--------PSYDLYAVI 1256
Query 61 VHSGELGGGHYYAYTKIRGQ---------WYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
H G + GGHY A ++ W F+DS VT V E + + AY+L Y R+
Sbjct 1257 NHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRN 1316
Query 112 S 112
S
Sbjct 1317 S 1317
> xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (proto-oncogene);
K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=975
Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 44/111 (39%), Positives = 62/111 (55%), Gaps = 17/111 (15%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNP-QYELIAV 59
LKRF + NR+ R K + V FP + L+M +F+ DP P Y+L+AV
Sbjct 842 LKRF-SYNRFWRDKLDAVVEFPIRD---LNMSEFVC----------DPQAGPFVYDLVAV 887
Query 60 NVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYE 108
+ H G +GGGHY AY K + QWY F+DS V+ ED+ + AY+L Y+
Sbjct 888 SDHYGGMGGGHYTAYAKNQDKDQWYYFDDSSVSPASEDQIVTKAAYVLFYQ 938
> dre:565434 usp8, fb92h07, wu:fb92h07; ubiquitin specific peptidase
8; K11839 ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
Length=1099
Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 15/107 (14%)
Query 3 RFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVNVH 62
RF RW R K T V FP + LD+ ++++ G L+ +Y L AV+ H
Sbjct 1003 RFKYEGRW-REKLQTLVDFPL---DNLDLSQYVI-GPKNNLK--------KYNLYAVSNH 1049
Query 63 SGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTY 107
G + GGHY AY K ++ +W++F+D V+ + S AY+ Y
Sbjct 1050 YGGMDGGHYTAYCKNPMKQRWFKFDDHEVSEISSSTVRSPAAYIFFY 1096
> mmu:30941 Usp21, ESTM28, Usp16, Usp23, W53272; ubiquitin specific
peptidase 21 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=566
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 14/109 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
L RF + +R S K++ V FP + L + F D + +P Y+L A+
Sbjct 464 LNRF-STSRGSIKKSSVGVDFPL---QRLSLGDF----------ASDKAGSPVYQLYALC 509
Query 61 VHSGELGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYEL 109
HSG + GHY A + + W+ +NDS V+ V E++ S++ Y+L Y+L
Sbjct 510 NHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQL 558
> hsa:27005 USP21, MGC3394, USP16, USP23; ubiquitin specific peptidase
21 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=565
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 14/109 (12%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
L RF + +R S K++ V FP + L + F D + +P Y+L A+
Sbjct 463 LNRF-SASRGSIKKSSVGVDFPL---QRLSLGDF----------ASDKAGSPVYQLYALC 508
Query 61 VHSGELGGGHYYAYTKIRGQWYEFNDSCVTAVHEDKCHSADAYMLTYEL 109
HSG + GHY A + + W+ +NDS V+ V E++ S++ Y+L Y+L
Sbjct 509 NHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQL 557
> mmu:76179 Usp31, 6330567E21Rik, mKIAA1203; ubiquitin specific
peptidase 31; K11852 ubiquitin carboxyl-terminal hydrolase
31 [EC:3.1.2.15]
Length=1344
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 27/61 (44%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Query 54 YELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
Y+L AV H G + GGHY AY K + G WY F+DS V + ED+ + AY+L Y+ R+
Sbjct 700 YDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRT 759
Query 112 S 112
+
Sbjct 760 A 760
> ath:AT5G22030 UBP8; UBP8 (UBIQUITIN-SPECIFIC PROTEASE 8); ubiquitin
thiolesterase/ ubiquitin-specific protease; K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=913
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 13/109 (11%)
Query 1 LKRFHNVNRWSRSKTNTRVCFPYKTGEYLDMKKFILPGGLEQLREEDPSFNPQYELIAVN 60
LKRF + +R+ ++K V FP + LD+ +I ++ +Y L A++
Sbjct 813 LKRF-SYSRFMKNKLEAYVDFPL---DNLDLSSYI--------SYKNGQTTYRYMLYAIS 860
Query 61 VHSGELGGGHYYAYTKIRG-QWYEFNDSCVTAVHEDKCHSADAYMLTYE 108
H G +GGGHY AY G +WY+F+DS V + ++K ++ AY+L Y+
Sbjct 861 NHYGSMGGGHYTAYVHHGGDRWYDFDDSHVHQISQEKIKTSAAYVLFYK 909
> hsa:57478 USP31, KIAA1203; ubiquitin specific peptidase 31 (EC:3.4.19.12);
K11852 ubiquitin carboxyl-terminal hydrolase
31 [EC:3.1.2.15]
Length=1352
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 27/61 (44%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Query 54 YELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
Y+L AV H G + GGHY AY K + G WY F+DS V + ED+ + AY+L Y+ R+
Sbjct 707 YDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRT 766
Query 112 S 112
+
Sbjct 767 A 767
> cel:T05H10.1 hypothetical protein; K11857 ubiquitin carboxyl-terminal
hydrolase 47 [EC:3.1.2.15]
Length=1326
Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 20/101 (19%)
Query 54 YELIAVNVHSGELGGGHYYAYTKIRGQ--WYEFNDSCV---TAVHEDKC----------H 98
YEL +V VHSG GGHY+AY K Q WY FND+ V T + +K
Sbjct 404 YELFSVMVHSGNAAGGHYFAYIKNLDQDRWYVFNDTRVDFATPLEIEKSFGGHPSGWNQS 463
Query 99 SADAYMLTYELRSSREDSMRRIAKVKAANRIPPHPSEQQQQ 139
+ +AYML Y R +R A+ +N++P H + Q++
Sbjct 464 NTNAYMLMY-----RRIDPKRNARFILSNQLPQHIKDSQEK 499
> dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiquitin
carboxyl-terminal hydrolase 31 [EC:3.1.2.15]
Length=1295
Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 28/61 (45%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
Query 54 YELIAVNVHSGELGGGHYYAYTK--IRGQWYEFNDSCVTAVHEDKCHSADAYMLTYELRS 111
Y+L AV H G + GGHY AY K I GQWY F+DS V V ++ AY+L Y+ R+
Sbjct 678 YDLYAVCNHHGNMHGGHYTAYCKNSIDGQWYCFDDSEVQPVADEDVCQQTAYILFYQRRT 737
Query 112 S 112
+
Sbjct 738 T 738
Lambda K H
0.317 0.132 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 2807590228
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40