bitscore colors: <40, 40-50 , 50-80, 80-200, >200
BLASTP 2.2.24+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
164,496 sequences; 82,071,388 total letters
Query= Eten_7612_orf2
Length=173
Score E
Sequences producing significant alignments: (Bits) Value
tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putat... 198 8e-51
pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative... 155 4e-38
mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiqu... 146 4e-35
xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (pr... 145 7e-35
dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin spec... 144 1e-34
hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin spec... 139 5e-33
mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap1... 137 3e-32
hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH... 137 3e-32
cel:H34C03.2 hypothetical protein; K11835 ubiquitin carboxyl-t... 136 3e-32
dre:568334 ubiquitin specific protease 11-like 133 4e-31
hsa:84669 USP32, NY-REN-60, USP10; ubiquitin specific peptidas... 131 9e-31
mmu:237898 Usp32, 2900074J03Rik, 6430526O11Rik, AW045245; ubiq... 131 9e-31
dre:557981 ubiquitin specific peptidase 15-like; K11837 ubiqui... 131 1e-30
ath:AT4G10570 UBP9; UBP9 (UBIQUITIN-SPECIFIC PROTEASE 9); cyst... 130 2e-30
ath:AT4G10590 UBP10; ubiquitin carboxyl-terminal hydrolase fam... 129 4e-30
hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.... 128 1e-29
ath:AT1G32850 UBP11; UBP11 (UBIQUITIN-SPECIFIC PROTEASE 11); c... 128 1e-29
mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;... 127 1e-29
hsa:9098 USP6, HRP1, TRE17, TRE2, Tre-2, USP6-short; ubiquitin... 127 2e-29
ath:AT2G40930 UBP5; UBP5 (UBIQUITIN-SPECIFIC PROTEASE 5); ubiq... 125 8e-29
mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin sp... 125 9e-29
hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3... 124 2e-28
dre:561425 novel protein similar to vertebrate ubiquitin speci... 124 2e-28
ath:AT5G22030 UBP8; UBP8 (UBIQUITIN-SPECIFIC PROTEASE 8); ubiq... 122 4e-28
cel:F07A11.4 hypothetical protein; K11847 ubiquitin carboxyl-t... 118 1e-26
xla:380243 usp8, MGC53905; ubiquitin specific peptidase 8 (EC:... 113 3e-25
hsa:9101 USP8, FLJ34456, HumORF8, KIAA0055, MGC129718, UBPY; u... 112 5e-25
sce:YJL197W UBP12; Ubiquitin carboxyl-terminal hydrolase, ubiq... 109 6e-24
mmu:84092 Usp8, AI574262, AW557536, Ubpy, mKIAA0055; ubiquitin... 108 1e-23
dre:565434 usp8, fb92h07, wu:fb92h07; ubiquitin specific pepti... 105 1e-22
dre:564054 ubiquitin specific peptidase 2-like; K11833 ubiquit... 93.2 4e-19
dre:100002673 ubiquitin specific peptidase 2-like; K11833 ubiq... 93.2 4e-19
mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific pepti... 87.4 2e-17
dre:494031 usp2a, zgc:92134; ubiquitin specific peptidase 2a (... 86.7 3e-17
hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC... 85.9 6e-17
sce:YDR069C DOA4, DOS1, MUT4, NPI2, SSV7, UBP4; Doa4p (EC:3.1.... 83.2 4e-16
dre:563546 CG14619-like; K11833 ubiquitin carboxyl-terminal hy... 77.4 2e-14
dre:563983 novel protein similar to vertebrate ubiquitin speci... 75.1 1e-13
hsa:57478 USP31, KIAA1203; ubiquitin specific peptidase 31 (EC... 75.1 1e-13
mmu:75083 Usp50, 1700086G18Rik, 4930511O11Rik; ubiquitin speci... 74.7 1e-13
mmu:76179 Usp31, 6330567E21Rik, mKIAA1203; ubiquitin specific ... 72.8 5e-13
dre:406508 usp33, zgc:77308; ubiquitin specific peptidase 33 (... 72.8 6e-13
dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiq... 71.6 1e-12
xla:100036785 usp3; ubiquitin specific peptidase 3 (EC:3.1.2.1... 71.2 2e-12
hsa:27005 USP21, MGC3394, USP16, USP23; ubiquitin specific pep... 71.2 2e-12
mmu:30941 Usp21, ESTM28, Usp16, Usp23, W53272; ubiquitin speci... 71.2 2e-12
cel:E01B7.1 hypothetical protein; K11839 ubiquitin carboxyl-te... 70.9 2e-12
mmu:235441 Usp3, AA409661, BC017156, MGC28886; ubiquitin speci... 70.1 3e-12
hsa:9960 USP3, MGC129878, MGC129879, SIH003, UBP; ubiquitin sp... 69.7 5e-12
cel:ZK328.1 cyk-3; CYtoKinesis defect family member (cyk-3); K... 68.6 1e-11
> tgo:TGME49_063420 ubiquitin carboxyl-terminal hydrolase, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1100
Score = 198 bits (503), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 92/135 (68%), Positives = 109/135 (80%), Gaps = 0/135 (0%)
Query 36 VDLWFATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRL 95
+D FA+GG+ GL NL NT FLN+AVQCLS VLP S YFLSG + ADINE+N MGTQGRL
Sbjct 345 IDEMFASGGICGLSNLGNTCFLNSAVQCLSKVLPLSYYFLSGKFVADINEENVMGTQGRL 404
Query 96 ADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNR 155
A AY TL+ +W E++ PR+LK AVG VREEFLG+ QQD+QEL+AFLLDG+HEDLNR
Sbjct 405 ARAYHATLRDMWFGGESSLAPRDLKAAVGRVREEFLGYNQQDSQELIAFLLDGLHEDLNR 464
Query 156 VRKKPYYEDKIEGCP 170
++KKPYYE KIEG P
Sbjct 465 IKKKPYYESKIEGGP 479
> pfa:PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative
(EC:3.1.2.15); K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=1332
Score = 155 bits (393), Expect = 4e-38, Method: Composition-based stats.
Identities = 72/131 (54%), Positives = 95/131 (72%), Gaps = 2/131 (1%)
Query 40 FATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAY 99
F GG GL+NL NT FLN+++QCLS +L FS YFL+G++ IN N +G GRLA AY
Sbjct 306 FDKGGDRGLINLGNTCFLNSSLQCLSKILKFSNYFLNGSFWNHINYSNPVGQHGRLAKAY 365
Query 100 AKTLKALWASN--ETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVR 157
+TL +W N + + P+ LK A+ E R+EF G+ Q D+QELLAFLLDG+HEDLN +R
Sbjct 366 YETLTEMWKINKRDCPYAPKVLKEAISEKRDEFYGYQQHDSQELLAFLLDGLHEDLNLIR 425
Query 158 KKPYYEDKIEG 168
KKPYYE+K++G
Sbjct 426 KKPYYEEKLQG 436
> mmu:22258 Usp4, F730026I20Rik, KIAA4155, Unp, mKIAA4155; ubiquitin
specific peptidase 4 (proto-oncogene) (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=962
Score = 146 bits (368), Expect = 4e-35, Method: Composition-based stats.
Identities = 65/122 (53%), Positives = 86/122 (70%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+A+QCLS P + YFL Y+A+IN N +G +G +A+AYA+ +
Sbjct 300 GLCGLGNLGNTCFMNSALQCLSNTAPLTEYFLKDEYEAEINRDNPLGMKGEIAEAYAELI 359
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K +W+ +T PR K VG +F G+ QQD+QELLAF+LDG+HEDLNRV+KKPY E
Sbjct 360 KQMWSGRDTHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFILDGLHEDLNRVKKKPYLE 419
Query 164 DK 165
K
Sbjct 420 PK 421
> xla:398480 usp4, MGC130831; ubiquitin specific peptidase 4 (proto-oncogene);
K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=975
Score = 145 bits (366), Expect = 7e-35, Method: Composition-based stats.
Identities = 65/122 (53%), Positives = 87/122 (71%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+A+QCLS P +RYFL+ YK +IN +N +G +G +A AYA+ +
Sbjct 320 GLCGLSNLGNTCFMNSALQCLSNSPPLTRYFLTDEYKKEINRENPLGMKGEIAVAYAELI 379
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ +W+ + + PR K VG +F G+ QQD+QELLAFLLDG+HEDLNRV+KKPY E
Sbjct 380 RQIWSGDHSYVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLE 439
Query 164 DK 165
K
Sbjct 440 LK 441
> dre:449927 usp4, im:7139722, unpEL, wu:fa11d11; ubiquitin specific
protease 4 (proto-oncogene); K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=1006
Score = 144 bits (363), Expect = 1e-34, Method: Composition-based stats.
Identities = 65/121 (53%), Positives = 84/121 (69%), Gaps = 0/121 (0%)
Query 41 ATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYA 100
A GL GL NL NT F+N+A+QCLS P + YFL Y+A+IN +N +G +G +A+AYA
Sbjct 311 AQPGLCGLSNLGNTCFMNSALQCLSNTPPLTEYFLEDRYEAEINRENPLGMRGEIAEAYA 370
Query 101 KTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
+K +W S + PR K VG +F G+ QQD+QELLAFLLDG+HEDLNRV+KKP
Sbjct 371 DLVKQMWLSRSSYVAPRTFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKP 430
Query 161 Y 161
Y
Sbjct 431 Y 431
> hsa:7375 USP4, MGC149848, MGC149849, UNP, Unph; ubiquitin specific
peptidase 4 (proto-oncogene) (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=963
Score = 139 bits (350), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 65/122 (53%), Positives = 85/122 (69%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+A+QCLS P + YFL Y+A+IN N +G +G +A+AYA+ +
Sbjct 300 GLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELI 359
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K +W+ + PR K VG +F G+ QQD+QELLAFLLDG+HEDLNRV+KKPY E
Sbjct 360 KQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLE 419
Query 164 DK 165
K
Sbjct 420 LK 421
> mmu:14479 Usp15, 4921514G19Rik, AI327321, E430033I05Rik, Gcap18,
mKIAA0529; ubiquitin specific peptidase 15 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=981
Score = 137 bits (344), Expect = 3e-32, Method: Composition-based stats.
Identities = 61/122 (50%), Positives = 83/122 (68%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+A+QCLS P + YFL+ Y+ ++N N +G +G +A +YA+ +
Sbjct 287 GLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELI 346
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K +W+ + PR K VG +F G+ QQD QELLAFLLDG+HEDLNR+RKKPY +
Sbjct 347 KQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQ 406
Query 164 DK 165
K
Sbjct 407 LK 408
> hsa:9958 USP15, KIAA0529, MGC131982, MGC149838, MGC74854, UNPH4;
ubiquitin specific peptidase 15 (EC:3.4.19.12); K11835
ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=952
Score = 137 bits (344), Expect = 3e-32, Method: Composition-based stats.
Identities = 61/122 (50%), Positives = 83/122 (68%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+A+QCLS P + YFL+ Y+ ++N N +G +G +A +YA+ +
Sbjct 258 GLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELI 317
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K +W+ + PR K VG +F G+ QQD QELLAFLLDG+HEDLNR+RKKPY +
Sbjct 318 KQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQ 377
Query 164 DK 165
K
Sbjct 378 LK 379
> cel:H34C03.2 hypothetical protein; K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=900
Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats.
Identities = 60/126 (47%), Positives = 83/126 (65%), Gaps = 0/126 (0%)
Query 42 TGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAK 101
T G GL NL NT F+ +A QCLS + P YFL+ Y+ DINE N +GT G LA A +
Sbjct 271 TPGACGLSNLGNTCFMASAFQCLSNMPPLREYFLANTYQNDINEDNPLGTHGHLAMAVGE 330
Query 102 TLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPY 161
+K +W+ + + PR+ K +G+ F G++QQD EL+A++LDG+HEDLNR++KKPY
Sbjct 331 LMKGMWSGDYASINPRKFKSIIGQFAPRFNGYSQQDAHELMAYVLDGLHEDLNRIKKKPY 390
Query 162 YEDKIE 167
ED E
Sbjct 391 IEDSDE 396
> dre:568334 ubiquitin specific protease 11-like
Length=658
Score = 133 bits (334), Expect = 4e-31, Method: Composition-based stats.
Identities = 61/132 (46%), Positives = 84/132 (63%), Gaps = 0/132 (0%)
Query 32 NDSLVDLWFATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGT 91
N + D + G+ GL NL NT F+N+A+QCLS P + YFL Y ++N N +G
Sbjct 279 NSADEDSYRGPPGVCGLTNLGNTCFMNSALQCLSNTPPLTEYFLKNLYLEELNFSNPLGM 338
Query 92 QGRLADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHE 151
+G +A+AYA +K +W+ + PR K VG +FLG+ Q D+QELL+FLLDG+HE
Sbjct 339 KGEIAEAYADVIKQMWSGRHYSVVPRVFKTKVGHFASQFLGYQQHDSQELLSFLLDGLHE 398
Query 152 DLNRVRKKPYYE 163
DLNRV+KK Y E
Sbjct 399 DLNRVKKKEYIE 410
> hsa:84669 USP32, NY-REN-60, USP10; ubiquitin specific peptidase
32 (EC:3.4.19.12); K11837 ubiquitin carboxyl-terminal hydrolase
6/32 [EC:3.1.2.15]
Length=1604
Score = 131 bits (330), Expect = 9e-31, Method: Composition-based stats.
Identities = 56/122 (45%), Positives = 81/122 (66%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GL NL NT F+N+++QC+S P ++YF+SG + ++N N +G +G +A Y +
Sbjct 732 GATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLV 791
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ LW+ + P +L+W + + F GF QQD+QELLAFLLDG+HEDLNRV +KPY E
Sbjct 792 QELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVE 851
Query 164 DK 165
K
Sbjct 852 LK 853
> mmu:237898 Usp32, 2900074J03Rik, 6430526O11Rik, AW045245; ubiquitin
specific peptidase 32 (EC:3.1.2.15); K11837 ubiquitin
carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1604
Score = 131 bits (330), Expect = 9e-31, Method: Composition-based stats.
Identities = 56/122 (45%), Positives = 81/122 (66%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GL NL NT F+N+++QC+S P ++YF+SG + ++N N +G +G +A Y +
Sbjct 732 GATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLV 791
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ LW+ + P +L+W + + F GF QQD+QELLAFLLDG+HEDLNRV +KPY E
Sbjct 792 QELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVE 851
Query 164 DK 165
K
Sbjct 852 LK 853
> dre:557981 ubiquitin specific peptidase 15-like; K11837 ubiquitin
carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1675
Score = 131 bits (329), Expect = 1e-30, Method: Composition-based stats.
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GL NL NT F+N+++QC+S P + YF+SG + ++N N +G +G +A Y +
Sbjct 822 GATGLSNLGNTCFMNSSIQCVSNTKPLTEYFISGRHLYELNRTNPIGMRGHMAKCYGDLV 881
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ LW+ + P +L+W + + F GF QQD+QELLAFLLDG+HEDLNRV +KPY E
Sbjct 882 QELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVE 941
Query 164 DK 165
K
Sbjct 942 LK 943
> ath:AT4G10570 UBP9; UBP9 (UBIQUITIN-SPECIFIC PROTEASE 9); cysteine-type
endopeptidase/ ubiquitin thiolesterase; K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=923
Score = 130 bits (328), Expect = 2e-30, Method: Composition-based stats.
Identities = 63/123 (51%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Query 43 GGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKT 102
GGL GL NL NT F+N+A+QCL+ P YFL Y DIN N +G G LA A+
Sbjct 301 GGLAGLSNLGNTCFMNSALQCLAHTPPIVEYFLQD-YSDDINRDNPLGMCGELAIAFGDL 359
Query 103 LKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYY 162
LK LW+S A PR K + +F G+ Q D+QELLAFLLDG+HEDLN+V++KPY
Sbjct 360 LKKLWSSGRNAVAPRAFKTKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYI 419
Query 163 EDK 165
E K
Sbjct 420 ELK 422
> ath:AT4G10590 UBP10; ubiquitin carboxyl-terminal hydrolase family
protein; K11835 ubiquitin carboxyl-terminal hydrolase
4/11/15 [EC:3.1.2.15]
Length=910
Score = 129 bits (325), Expect = 4e-30, Method: Composition-based stats.
Identities = 62/123 (50%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Query 43 GGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKT 102
GGL GL NL NT F+N+A+QCL+ P YFL Y DIN N +G G LA A+
Sbjct 300 GGLAGLSNLGNTCFMNSALQCLAHTPPIVEYFLQD-YSDDINRDNPLGMCGELAIAFGDL 358
Query 103 LKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYY 162
LK LW+S + PR K + +F G+ Q D+QELLAFLLDG+HEDLN+V++KPY
Sbjct 359 LKKLWSSGRNSVAPRAFKTKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYI 418
Query 163 EDK 165
E K
Sbjct 419 ELK 421
> hsa:8237 USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.19.12);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15
[EC:3.1.2.15]
Length=963
Score = 128 bits (321), Expect = 1e-29, Method: Composition-based stats.
Identities = 58/120 (48%), Positives = 81/120 (67%), Gaps = 0/120 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G+ GL NL NT F+N+A+QCLS V + YFL+ Y ++N +N +G +G +A+AYA +
Sbjct 307 GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLV 366
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K W+ + + P K VG +FLG+ Q D+QELL+FLLDG+HEDLNRV+KK Y E
Sbjct 367 KQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVE 426
> ath:AT1G32850 UBP11; UBP11 (UBIQUITIN-SPECIFIC PROTEASE 11);
cysteine-type endopeptidase/ ubiquitin thiolesterase; K11835
ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=892
Score = 128 bits (321), Expect = 1e-29, Method: Composition-based stats.
Identities = 58/122 (47%), Positives = 81/122 (66%), Gaps = 1/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+ +QCL+ P YFL Y++DIN +N +G +G LA A+ + L
Sbjct 299 GLGGLQNLGNTCFMNSTLQCLAHTPPIVEYFLQD-YRSDINAKNPLGMRGELAIAFGELL 357
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ LW+S + PR K + +F G+ Q D+QE+LAFLLDG+HEDLN+V++KPY E
Sbjct 358 RKLWSSGQNTVAPRAFKTKLARFAPQFSGYNQHDSQEMLAFLLDGLHEDLNKVKRKPYIE 417
Query 164 DK 165
K
Sbjct 418 AK 419
> mmu:236733 Usp11, 6230415D12Rik, KIAA4085, MGC6649, mKIAA4085;
ubiquitin specific peptidase 11 (EC:3.4.19.12); K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=921
Score = 127 bits (320), Expect = 1e-29, Method: Composition-based stats.
Identities = 59/120 (49%), Positives = 80/120 (66%), Gaps = 0/120 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G+ GL NL NT F+N+A+QCLS V + YFL+ Y ++N +N +G +G LA+AYA +
Sbjct 255 GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLV 314
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
K W+ + P K VG +FLG+ Q D+QELL+FLLDG+HEDLNRV+KK Y E
Sbjct 315 KQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVE 374
> hsa:9098 USP6, HRP1, TRE17, TRE2, Tre-2, USP6-short; ubiquitin
specific peptidase 6 (Tre-2 oncogene) (EC:3.4.19.12); K11837
ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1406
Score = 127 bits (318), Expect = 2e-29, Method: Composition-based stats.
Identities = 55/122 (45%), Positives = 82/122 (67%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GL NL NT F+N+++QC+S P ++YF+SG + ++N N +G +G +A Y +
Sbjct 530 GATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLV 589
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ LW+ + + P +L+ + + +F GF QQD+QELLAFLLDG+HEDLNRV +KPY E
Sbjct 590 QELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVE 649
Query 164 DK 165
K
Sbjct 650 LK 651
> ath:AT2G40930 UBP5; UBP5 (UBIQUITIN-SPECIFIC PROTEASE 5); ubiquitin-specific
protease; K11835 ubiquitin carboxyl-terminal
hydrolase 4/11/15 [EC:3.1.2.15]
Length=924
Score = 125 bits (314), Expect = 8e-29, Method: Composition-based stats.
Identities = 60/125 (48%), Positives = 77/125 (61%), Gaps = 1/125 (0%)
Query 41 ATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYA 100
+T GL GL+NL NT F+N+A+QCL F+ YF Y +IN QN +G G LA A+
Sbjct 312 STAGLTGLLNLGNTCFMNSAIQCLVHTPEFASYFQED-YHQEINWQNPLGMVGELALAFG 370
Query 101 KTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
L+ LWA T PR K + +F G+ Q D+QELLAFLLDG+HEDLNRV+ KP
Sbjct 371 DLLRKLWAPGRTPIAPRPFKAKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNRVKHKP 430
Query 161 YYEDK 165
Y +
Sbjct 431 YINSR 435
> mmu:71472 Usp19, 8430421I07Rik, AI047774, Zmynd9; ubiquitin
specific peptidase 19 (EC:3.4.19.12); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1324
Score = 125 bits (313), Expect = 9e-29, Method: Composition-based stats.
Identities = 58/120 (48%), Positives = 76/120 (63%), Gaps = 0/120 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GLVNL NT F+N+ +Q LS +F +++A+IN N +GT GRLA +A L
Sbjct 538 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLL 597
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ALW AF P +LK V +F G+AQ D QE +AFLLDG+HEDLNR++ KPY E
Sbjct 598 RALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTE 657
> hsa:10869 USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3.4.19.12);
K11847 ubiquitin carboxyl-terminal hydrolase 19
[EC:3.1.2.15]
Length=1419
Score = 124 bits (311), Expect = 2e-28, Method: Composition-based stats.
Identities = 58/120 (48%), Positives = 76/120 (63%), Gaps = 0/120 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GLVNL NT F+N+ +Q LS +F +++A+IN N +GT GRLA +A L
Sbjct 596 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLL 655
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ALW AF P +LK V +F G+AQ D QE +AFLLDG+HEDLNR++ KPY E
Sbjct 656 RALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTE 715
> dre:561425 novel protein similar to vertebrate ubiquitin specific
peptidase 19 (USP19); K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1489
Score = 124 bits (311), Expect = 2e-28, Method: Composition-based stats.
Identities = 58/120 (48%), Positives = 75/120 (62%), Gaps = 0/120 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GLVNL NT F+N+ +Q LS YF ++++IN N +GT GRLA +A L
Sbjct 636 GFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRGFESEINCNNPLGTGGRLAIGFAVLL 695
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
+ALW AF P +LK V +F G+AQ D QE +AFLLDG+HEDLNR++ KPY E
Sbjct 696 RALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTE 755
> ath:AT5G22030 UBP8; UBP8 (UBIQUITIN-SPECIFIC PROTEASE 8); ubiquitin
thiolesterase/ ubiquitin-specific protease; K11835 ubiquitin
carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
Length=913
Score = 122 bits (307), Expect = 4e-28, Method: Composition-based stats.
Identities = 59/125 (47%), Positives = 78/125 (62%), Gaps = 1/125 (0%)
Query 41 ATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYA 100
T GL GL NL NT F+N+++QCL+ +FL G Y +IN N +G +G +A A+
Sbjct 316 GTLGLTGLQNLGNTCFMNSSLQCLAHTPKLVDFFL-GEYSKEINLDNPLGMKGEIALAFG 374
Query 101 KTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
L++LWA + PR K + +F GF Q D+QELLAFLLDG+HEDLNRV+ KP
Sbjct 375 DLLRSLWAPGASTVAPRTFKAKLARFAPQFSGFNQHDSQELLAFLLDGLHEDLNRVKNKP 434
Query 161 YYEDK 165
Y E K
Sbjct 435 YVEAK 439
> cel:F07A11.4 hypothetical protein; K11847 ubiquitin carboxyl-terminal
hydrolase 19 [EC:3.1.2.15]
Length=1095
Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats.
Identities = 53/117 (45%), Positives = 75/117 (64%), Gaps = 0/117 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GL N+ NT F+NA +Q L + YFL Y+ +INE N +G++GRLA A+A +
Sbjct 421 GYTGLRNIGNTCFMNAVLQMLVNNIELREYFLRNHYQPEINETNPLGSEGRLAKAFADFM 480
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
+W+ ++ A P ++K V E +F FAQ D E L+FLLDG+HED+NRV+KKP
Sbjct 481 HQMWSGHQKAIEPTQIKNIVAEKASQFANFAQHDAHEFLSFLLDGLHEDVNRVKKKP 537
> xla:380243 usp8, MGC53905; ubiquitin specific peptidase 8 (EC:3.1.2.15);
K11839 ubiquitin carboxyl-terminal hydrolase 8
[EC:3.1.2.15]
Length=1063
Score = 113 bits (283), Expect = 3e-25, Method: Composition-based stats.
Identities = 51/126 (40%), Positives = 77/126 (61%), Gaps = 2/126 (1%)
Query 41 ATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYA 100
A L GL NL NT ++N+ +QCL + YF Y+ADIN N +G +G +A+ +
Sbjct 718 AGPALTGLRNLGNTCYMNSILQCLCNTPHLAEYFNKNCYQADINRSNLLGHKGEVAEEFG 777
Query 101 KTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRV--RK 158
+KALW P++ K +G++ E+F G++ QD+QELL FL+DG+HEDLN+ RK
Sbjct 778 CIMKALWTGQYKCISPKDFKITIGKINEQFAGYSHQDSQELLLFLMDGLHEDLNKADNRK 837
Query 159 KPYYED 164
+ E+
Sbjct 838 RQKEEN 843
> hsa:9101 USP8, FLJ34456, HumORF8, KIAA0055, MGC129718, UBPY;
ubiquitin specific peptidase 8 (EC:3.4.19.12); K11839 ubiquitin
carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
Length=1118
Score = 112 bits (281), Expect = 5e-25, Method: Composition-based stats.
Identities = 47/122 (38%), Positives = 76/122 (62%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
L GL NL NT ++N+ +QCL + YF Y+ DIN N +G +G +A+ + +
Sbjct 775 ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIM 834
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
KALW P++ K +G++ ++F G++QQD+QELL FL+DG+HEDLN+ + Y+
Sbjct 835 KALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYK 894
Query 164 DK 165
++
Sbjct 895 EE 896
> sce:YJL197W UBP12; Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific
protease present in the nucleus and cytoplasm
that cleaves ubiquitin from ubiquitinated proteins (EC:3.1.2.15);
K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15
[EC:3.1.2.15]
Length=1254
Score = 109 bits (272), Expect = 6e-24, Method: Composition-based stats.
Identities = 54/126 (42%), Positives = 75/126 (59%), Gaps = 6/126 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G GLVNL NT ++N+A+QCL + YFL Y+ +INE+N +G G +A A++ +
Sbjct 362 GTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLV 421
Query 104 KALWASN------ETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVR 157
+ L+ + AF P K +G F G+ QQD+QE LAFLLD +HEDLNR+
Sbjct 422 QKLFQNRMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRII 481
Query 158 KKPYYE 163
KK Y E
Sbjct 482 KKEYTE 487
> mmu:84092 Usp8, AI574262, AW557536, Ubpy, mKIAA0055; ubiquitin
specific peptidase 8 (EC:3.4.19.12); K11839 ubiquitin carboxyl-terminal
hydrolase 8 [EC:3.1.2.15]
Length=1080
Score = 108 bits (269), Expect = 1e-23, Method: Composition-based stats.
Identities = 46/122 (37%), Positives = 75/122 (61%), Gaps = 0/122 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
L GL NL NT ++N+ +QCL + YF Y+ DIN N +G +G +A+ + +
Sbjct 737 ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIM 796
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKPYYE 163
KALW P++ K +G++ ++F G +QQD+QELL FL+DG+HEDLN+ + ++
Sbjct 797 KALWTGQYRYISPKDFKVTIGKINDQFAGSSQQDSQELLLFLMDGLHEDLNKADNRKRHK 856
Query 164 DK 165
++
Sbjct 857 EE 858
> dre:565434 usp8, fb92h07, wu:fb92h07; ubiquitin specific peptidase
8; K11839 ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
Length=1099
Score = 105 bits (261), Expect = 1e-22, Method: Composition-based stats.
Identities = 47/124 (37%), Positives = 75/124 (60%), Gaps = 1/124 (0%)
Query 45 LVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTLK 104
L GL NL NT ++N+ +QCL + + YF Y+ DIN N +G +G +A+ ++ +K
Sbjct 739 LTGLRNLGNTCYMNSILQCLCNTVAMADYFNRNYYQDDINRANILGHKGEVAEEFSVVMK 798
Query 105 ALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRV-RKKPYYE 163
ALW P + K + ++ F + QD+QELL FL+DG+HEDLN+ +++ Y E
Sbjct 799 ALWLGQYKMISPLDFKGTICKINSRFSSYEHQDSQELLLFLMDGLHEDLNKADKRRGYKE 858
Query 164 DKIE 167
++IE
Sbjct 859 EEIE 862
> dre:564054 ubiquitin specific peptidase 2-like; K11833 ubiquitin
carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
Length=398
Score = 93.2 bits (230), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 69/118 (58%), Gaps = 5/118 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GLVGL NL NT F+N+ +QCLS Y L ++ D+N NC + L D +AK
Sbjct 60 GLVGLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRTDLN-NNCRA-KAALMDEFAKLT 117
Query 104 KALW--ASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKK 159
+ +W ASNE A P + K + + F+G+ QQD QE L FLLDG+H ++NRV K
Sbjct 118 QTIWTSASNE-AISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVK 174
> dre:100002673 ubiquitin specific peptidase 2-like; K11833 ubiquitin
carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
Length=398
Score = 93.2 bits (230), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 69/118 (58%), Gaps = 5/118 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GLVGL NL NT F+N+ +QCLS Y L ++ D+N NC + L D +AK
Sbjct 60 GLVGLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRTDLN-NNCRA-KAALMDEFAKLT 117
Query 104 KALW--ASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKK 159
+ +W ASNE A P + K + + F+G+ QQD QE L FLLDG+H ++NRV K
Sbjct 118 QTIWTSASNE-AISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVK 174
> mmu:53376 Usp2, B930035K21Rik, Ubp41; ubiquitin specific peptidase
2 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=619
Score = 87.4 bits (215), Expect = 2e-17, Method: Composition-based stats.
Identities = 45/118 (38%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+ +QCLS Y L Y D+ + T L + +AK +
Sbjct 279 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLGHTSSAHTA--LMEEFAKLI 336
Query 104 KALWASNET-AFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
+ +W S+ P E K + F+G+ QQD QE L FLLDG+H ++NRV +P
Sbjct 337 QTIWTSSPNDVVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARP 394
> dre:494031 usp2a, zgc:92134; ubiquitin specific peptidase 2a
(EC:3.1.2.15); K11833 ubiquitin carboxyl-terminal hydrolase
2/21 [EC:3.1.2.15]
Length=391
Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 46/118 (38%), Positives = 67/118 (56%), Gaps = 3/118 (2%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GLVGL NL NT F+N+ +QCLS Y L +++ D+N N T L + +AK +
Sbjct 56 GLVGLRNLGNTCFMNSILQCLSNTQSLRDYCLHNSHRRDLNNNN--RTHTALMEEFAKLI 113
Query 104 KALWASNETAFGPR-ELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
+ +W S+ + E K + F+G+ QQD QE L FLLDG+H ++NRV +P
Sbjct 114 QTMWTSSSSEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRP 171
> hsa:9099 USP2, UBP41, USP9; ubiquitin specific peptidase 2 (EC:3.4.19.12);
K11833 ubiquitin carboxyl-terminal hydrolase
2/21 [EC:3.1.2.15]
Length=605
Score = 85.9 bits (211), Expect = 6e-17, Method: Composition-based stats.
Identities = 45/118 (38%), Positives = 64/118 (54%), Gaps = 3/118 (2%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
GL GL NL NT F+N+ +QCLS Y L Y D++ + T L + +AK +
Sbjct 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTA--LVEEFAKLI 322
Query 104 KALWASNET-AFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRKKP 160
+ +W S+ P E K + F+G+ QQD QE L FLLDG+H ++NRV +P
Sbjct 323 QTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRP 380
> sce:YDR069C DOA4, DOS1, MUT4, NPI2, SSV7, UBP4; Doa4p (EC:3.1.2.15);
K11839 ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
Length=926
Score = 83.2 bits (204), Expect = 4e-16, Method: Composition-based stats.
Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 9/129 (6%)
Query 37 DLWFATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLA 96
DL FA VGL NL N+ ++N +QC+ ++ FL +Y IN + +G++G LA
Sbjct 557 DLDFA----VGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILA 612
Query 97 DAYAKTLKALW-----ASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHE 151
+A+ + ++ S + + P + K A G V F +QQD QE FLLDG+HE
Sbjct 613 KYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHE 672
Query 152 DLNRVRKKP 160
DLN+ P
Sbjct 673 DLNQCGSNP 681
> dre:563546 CG14619-like; K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=404
Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 50/131 (38%), Positives = 63/131 (48%), Gaps = 15/131 (11%)
Query 43 GGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKT 102
G VGL N+ NT FLNA VQCLS Y L AY D + + L D ++K
Sbjct 59 NGQVGLRNVGNTCFLNAIVQCLSHTRSLRDYCLMRAYVQDKHS----NQEPVLMDEFSKV 114
Query 103 LKALWA--SNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRV---- 156
L LW + ET P + E F G++QQD QE L FLLD +H ++NR
Sbjct 115 LAGLWECDAGETTVNPGKFYRVFKESVPYFSGYSQQDAQEFLRFLLDRLHTEINRRPSKR 174
Query 157 -----RKKPYY 162
RK+P Y
Sbjct 175 PAVIERKEPAY 185
> dre:563983 novel protein similar to vertebrate ubiquitin specific
protease 43 (USP43) (EC:3.1.2.15); K11856 ubiquitin carboxyl-terminal
hydrolase 43 [EC:3.1.2.15]
Length=1122
Score = 75.1 bits (183), Expect = 1e-13, Method: Composition-based stats.
Identities = 44/119 (36%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query 42 TGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMG------TQGRL 95
T G+ GL N NT F+NA VQCLS + Y YK ++NE+ G +G +
Sbjct 110 TPGVQGLKNHGNTCFMNAVVQCLSNTELLAEYLGLEQYKYELNERRINGMMKSEEVRGEV 169
Query 96 ADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLN 154
D A ++ALW ++ T + K V + +F G AQ D E L +LLD +HED N
Sbjct 170 TDKLASLVRALWTNDYTPQLSVDFKSVVAKYGSQFKGNAQHDALEFLLWLLDCVHEDAN 228
> hsa:57478 USP31, KIAA1203; ubiquitin specific peptidase 31 (EC:3.4.19.12);
K11852 ubiquitin carboxyl-terminal hydrolase
31 [EC:3.1.2.15]
Length=1352
Score = 75.1 bits (183), Expect = 1e-13, Method: Composition-based stats.
Identities = 45/125 (36%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKA-------DINEQNCMGTQGR-- 94
G+ GL N NT F+NA +QCLS F+ Y G Y+A D + G QG+
Sbjct 126 GVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQGE 185
Query 95 LADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLN 154
+ + A ++ALW T R+ K V + ++ G +Q D QE L +LLD +HEDLN
Sbjct 186 VTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLN 245
Query 155 RVRKK 159
K+
Sbjct 246 HSVKQ 250
> mmu:75083 Usp50, 1700086G18Rik, 4930511O11Rik; ubiquitin specific
peptidase 50 (EC:3.4.19.12)
Length=390
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 40/112 (35%), Positives = 60/112 (53%), Gaps = 5/112 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G+ GL NL NT ++NA +QCL +V P YFLSG Y + +++C + A+A +
Sbjct 43 GVTGLRNLGNTCYMNAILQCLCSVSPLVEYFLSGKYITAL-KKDC----SEVTTAFAYLM 97
Query 104 KALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNR 155
+W + P AVG + FL QQD QE L ++L+ +HE L +
Sbjct 98 TDMWLGDSDCVSPEIFLSAVGSLYPAFLKKTQQDAQEFLIYVLNELHEALKK 149
> mmu:76179 Usp31, 6330567E21Rik, mKIAA1203; ubiquitin specific
peptidase 31; K11852 ubiquitin carboxyl-terminal hydrolase
31 [EC:3.1.2.15]
Length=1344
Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats.
Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGT---------QGR 94
G+ GL N NT F+NA +QCLS F+ Y G Y+A E QG
Sbjct 121 GVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPEPESEQPAGRGPHGQGE 180
Query 95 LADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLN 154
+ + A ++ALW T R+ K V + ++ G +Q D QE L +LLD +HEDLN
Sbjct 181 VTEQLAHLVRALWTLEYTPQHSRDFKSIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLN 240
Query 155 RVRKK 159
K+
Sbjct 241 HAVKQ 245
> dre:406508 usp33, zgc:77308; ubiquitin specific peptidase 33
(EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal hydrolase
20/33 [EC:3.1.2.15]
Length=897
Score = 72.8 bits (177), Expect = 6e-13, Method: Composition-based stats.
Identities = 43/122 (35%), Positives = 64/122 (52%), Gaps = 11/122 (9%)
Query 42 TGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLS--GAYKADINEQNCMGTQGRLADAY 99
T GL GL N+ NT ++NAA+Q LS P +++FL G K D + L +Y
Sbjct 152 TRGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLECGGLVKTD--------KKPALCKSY 203
Query 100 AKTLKALWASNETAF-GPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRK 158
K + LW N ++ P L + V F G++QQD+QE L L+D +HE+L +
Sbjct 204 QKLVTDLWHKNRNSYVVPTNLFQGIKAVNPMFRGYSQQDSQEFLRCLMDQLHEELKELIP 263
Query 159 KP 160
+P
Sbjct 264 EP 265
> dre:564487 usp31; ubiquitin specific peptidase 31; K11852 ubiquitin
carboxyl-terminal hydrolase 31 [EC:3.1.2.15]
Length=1295
Score = 71.6 bits (174), Expect = 1e-12, Method: Composition-based stats.
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGT-----------Q 92
G+ GL N NT F+NA +QCLS F+ Y Y+ D + T +
Sbjct 89 GVAGLKNHGNTCFMNAILQCLSNTELFAEYLALEQYRGDQTDDEKPKTNGVVGRKGAQDR 148
Query 93 GRLADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHED 152
G + + + ++ALW T R+ K AV ++ G AQ D QE L +LLD +HED
Sbjct 149 GEVTEQLSGLVRALWTFEYTPQHSRDFKNAVSRSAMQYRGNAQHDAQEFLLWLLDRVHED 208
Query 153 LNRV 156
LN +
Sbjct 209 LNHL 212
> xla:100036785 usp3; ubiquitin specific peptidase 3 (EC:3.1.2.15);
K11986 ubiquitin carboxyl-terminal hydrolase 3 [EC:3.1.2.15]
Length=522
Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 45/136 (33%), Positives = 67/136 (49%), Gaps = 12/136 (8%)
Query 30 GLNDSLVDLWFATGGL--VGLVNLANTFFLNAAVQCLSAVLPFSRYFL----------SG 77
L+ L+ + +T L GL NL NT F+NA +Q LS + F YF
Sbjct 143 SLSKKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKT 202
Query 78 AYKADINEQNCMGTQGRLADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQD 137
A + + ++ L + + KTL ALW N+TAF P L + V ++ F G+ QQD
Sbjct 203 AGRRTYHTRSQGDVNVSLVEEFRKTLCALWQGNQTAFSPESLFYVVWKIMPNFRGYQQQD 262
Query 138 TQELLAFLLDGIHEDL 153
E + +LLD +H +L
Sbjct 263 AHEFMRYLLDHLHLEL 278
> hsa:27005 USP21, MGC3394, USP16, USP23; ubiquitin specific peptidase
21 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=565
Score = 71.2 bits (173), Expect = 2e-12, Method: Composition-based stats.
Identities = 41/119 (34%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G VGL NL NT FLNA +QCLS+ P + L ++ ++ G L +A+A +
Sbjct 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFADVI 266
Query 104 KALWASNE-TAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRV-RKKP 160
ALW + A P + + F G++QQD QE L L++ +H ++NR R+ P
Sbjct 267 GALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAP 325
> mmu:30941 Usp21, ESTM28, Usp16, Usp23, W53272; ubiquitin specific
peptidase 21 (EC:3.4.19.12); K11833 ubiquitin carboxyl-terminal
hydrolase 2/21 [EC:3.1.2.15]
Length=566
Score = 71.2 bits (173), Expect = 2e-12, Method: Composition-based stats.
Identities = 41/119 (34%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCMGTQGRLADAYAKTL 103
G VGL NL NT FLNA +QCLS+ P + L ++ ++ G L +A+A +
Sbjct 210 GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFADVI 266
Query 104 KALWASNE-TAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRV-RKKP 160
ALW + A P + + F G++QQD QE L L++ +H ++NR R+ P
Sbjct 267 GALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAP 325
> cel:E01B7.1 hypothetical protein; K11839 ubiquitin carboxyl-terminal
hydrolase 8 [EC:3.1.2.15]
Length=811
Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats.
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 2/149 (1%)
Query 26 AVPRGLNDSLVDLWFATGGLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINE 85
A+ R ++DS + G VGL N+ NT F++A +QCL + F + + +N
Sbjct 458 AIHRVVDDSTRNKGRGVPGAVGLFNMGNTCFMSATLQCLFQTPGLAEVFTKKVFVSKVNT 517
Query 86 QNCMGTQGRLADAYAKTLKALWASNETAFGP-RELKWAVGEVREEFLGFAQQDTQELLAF 144
Q+ +G++G ++ +A +W TA P R L+ V + Q D E F
Sbjct 518 QSRLGSKGVISAGFASLSDMIWNGTFTAIRPSRFLQLFSDTVYQPLSDGRQHDASEFQIF 577
Query 145 LLDGIHEDLNRVRKKPYYEDKIEGCPGLS 173
LLD +HED N+ ++ +E G G++
Sbjct 578 LLDALHEDTNQAQRIS-FEQNYHGGAGIA 605
> mmu:235441 Usp3, AA409661, BC017156, MGC28886; ubiquitin specific
peptidase 3 (EC:3.4.19.12); K11986 ubiquitin carboxyl-terminal
hydrolase 3 [EC:3.1.2.15]
Length=520
Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 44/136 (32%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query 30 GLNDSLVDLWFATGGL--VGLVNLANTFFLNAAVQCLSAVLPFSRYFL----------SG 77
LN L+ + +T + GL NL NT F+NA +Q LS + F YF
Sbjct 141 SLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKT 200
Query 78 AYKADINEQNCMGTQGRLADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQD 137
A + + ++ + L + + KTL ALW ++TAF P L + V ++ F G+ QQD
Sbjct 201 AGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQD 260
Query 138 TQELLAFLLDGIHEDL 153
E + +LLD +H +L
Sbjct 261 AHEFMRYLLDHLHLEL 276
> hsa:9960 USP3, MGC129878, MGC129879, SIH003, UBP; ubiquitin
specific peptidase 3 (EC:3.4.19.12); K11986 ubiquitin carboxyl-terminal
hydrolase 3 [EC:3.1.2.15]
Length=520
Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 12/135 (8%)
Query 31 LNDSLVDLWFATGGL--VGLVNLANTFFLNAAVQCLSAVLPFSRYFL----------SGA 78
LN L+ + +T + GL NL NT F+NA +Q LS + F YF A
Sbjct 142 LNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTA 201
Query 79 YKADINEQNCMGTQGRLADAYAKTLKALWASNETAFGPRELKWAVGEVREEFLGFAQQDT 138
+ + ++ L + + KTL ALW ++TAF P L + V ++ F G+ QQD
Sbjct 202 GRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDA 261
Query 139 QELLAFLLDGIHEDL 153
E + +LLD +H +L
Sbjct 262 HEFMRYLLDHLHLEL 276
> cel:ZK328.1 cyk-3; CYtoKinesis defect family member (cyk-3);
K11837 ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
Length=1178
Score = 68.6 bits (166), Expect = 1e-11, Method: Composition-based stats.
Identities = 40/116 (34%), Positives = 55/116 (47%), Gaps = 1/116 (0%)
Query 44 GLVGLVNLANTFFLNAAVQCLSAVLPFSRYFLSGAYKADINEQNCM-GTQGRLADAYAKT 102
G VGLVN N + NA +QCL+ V P ++YFL I N G YAK
Sbjct 568 GAVGLVNYGNFCYRNAGIQCLARVSPLTQYFLDEDNLDAIKRGNLRRGDAAETTIEYAKL 627
Query 103 LKALWASNETAFGPRELKWAVGEVREEFLGFAQQDTQELLAFLLDGIHEDLNRVRK 158
L+ +WA+ + P + A+ + F Q D QE +AFLLD +H + K
Sbjct 628 LREMWAAKKKNIAPNDFNDAIRLSSDMFECSEQHDCQEFVAFLLDQLHTSMYESNK 683
Lambda K H
0.324 0.138 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 4406352944
Database: egene_temp_file_orthology_annotation_similarity_blast_database_866
Posted date: Sep 17, 2011 2:57 PM
Number of letters in database: 82,071,388
Number of sequences in database: 164,496
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40